2,050,333 results match your criteria Comparative Effectiveness Research [Journal]


Types of materials for frontalis sling surgery for congenital ptosis.

Cochrane Database Syst Rev 2019 Apr 23;4:CD012725. Epub 2019 Apr 23.

Department of Ophthalmology, Montefiore Medical Center, Albert Einstein College of Medicine, 3332 Rochambeau Avenue, 3rd Floor, Bronx, NY, USA, 10467.

Background: Congenital ptosis is a drooping of one or both eyelids at birth, often due to poor development of the levator palpebrae superioris muscle. This can result in amblyopia, astigmatism, and ocular torticollis and therefore may necessitate surgical intervention in early childhood if visual development is compromised. Patients may have varied levels of levator function. Read More

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http://dx.doi.org/10.1002/14651858.CD012725.pub2DOI Listing

An ecological view of measurement: focus on multilevel model explanation of differential item functioning.

Psicothema 2019 May;31(2):194-203

University of British Columbia.

Background: The 3rd Regional Comparative and Explanatory Study reports, analyses and compares academic results in mathematics, sciences, and reading for 15 Latin American countries. Validity is the foundation of a testing procedure, and the process of validation is important to the overall success of educational assessment as a whole. This methodological study deals specifically with an ecological point of view which includes and situates the person, process, context, and time of the testing situation. Read More

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http://dx.doi.org/10.7334/psicothema2018.303DOI Listing

Sociodemographic variables, risk factors, and protective factors contributing to youth recidivism.

Psicothema 2019 May;31(2):128-133

Universitat Jaume I.

Background: This study explores the predictive capabilities of sociodemographic characteristics and risk and protective factors for youth recidivism while comparing two analytical methodologies; logistic prediction models and qualitative comparative analysis models.

Methods: information from the judicial files of 389 young offenders (14-19.03 years) were gathered from the Juvenile Court and risk and protective factors were extracted from the administration of the Youth Level Service/Case Management Inventory. Read More

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http://dx.doi.org/10.7334/psicothema2018.257DOI Listing

COMPARATIVE EFFICACY AND SAFETY OF THREE CURRENT CLINICAL TREATMENTS FOR GIRLS WITH CENTRAL PRECOCIOUS PUBERTY: A NETWORK META-ANALYSIS.

Endocr Pract 2019 Apr 23. Epub 2019 Apr 23.

From: 1Department of Nutrition, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

: The optimal treatment for girls with central precocious puberty (CPP) is unknown. We conducted a network meta-analysis to evaluate the efficacy and safety of existing treatments to provide credible clinical guidelines. We compared gonadotropin-releasing hormone analogue (GnRHa) therapy, GnRHa plus growth hormone (GH) combination therapy, and no-treatment therapy to treat girls with CPP by performing an electronic search for studies in PubMed, Embase, Chinese National Knowledge Infrastructure databases, and Wanfang Data from their inception until 30 September 2018. Read More

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http://journals.aace.com/doi/10.4158/EP-2019-0008
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http://dx.doi.org/10.4158/EP-2019-0008DOI Listing
April 2019
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A comparative study on the effectiveness of herbal extracts vs 2.5% benzoyl peroxide in the treatment of mild to moderate acne vulgaris.

J Cosmet Dermatol 2019 Apr 23. Epub 2019 Apr 23.

Skin Center, Srinakharinwirot University, Bangkok, Thailand.

Background: Although there is a standard guideline for the treatment of acne, it is still a common skin disease, and suboptimal medication adherence is a major reason for treatment failure. Herbal extracts are an interesting alternative medicine because they consist of a variety of active ingredients. Moreover, herbal extracts may have improved therapeutic efficacy because of the combination of various herbs. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.12962
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http://dx.doi.org/10.1111/jocd.12962DOI Listing
April 2019
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Knowledge and expertise in care practices: the role of the peer worker in mental health teams.

Sociol Health Illn 2019 Apr 23. Epub 2019 Apr 23.

Population Health Research Institute, St George's University of London, London, UK.

Our research examines how different forms of knowledge and expertise are increasingly important in caring for people experiencing mental illness. We build on theoretical developments regarding multiple ontologies of knowing about illness. We examine how experiential knowledge of mental health problems, learned by being subject to illness rather than through objective study, is enacted in mental healthcare teams. Read More

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http://dx.doi.org/10.1111/1467-9566.12944DOI Listing

What Prompts Policy Change? Comparative Analyses of Efforts to Create Age-Friendly Cities in 14 Cities in Indonesia.

J Aging Soc Policy 2019 Apr 23:1-21. Epub 2019 Apr 23.

a SurveyMETER , Yogyakarta , Indonesia.

Four years after an age-friendly city (AFC) assessment across Indonesia, this article presents a comparative analysis of policy changes that have taken place across different AFC dimensions and factors associated with more and less change. Nine of fourteen cities initiated changes, ranging from public declarations, regulations, and creation or expansion of services. Our findings suggest that the AFC assessment can offer a means to engage policy makers, which in turn may facilitate city-level change, particularly for larger cities with more substantive budgets and more consolidated rather than dispersed leadership; however, no single factor represented a sufficient or necessary condition for change. Read More

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http://dx.doi.org/10.1080/08959420.2019.1589889DOI Listing

Psychopharmacology and ethnicity: A comparative study on Senegalese and Italian men.

World J Biol Psychiatry 2019 Apr 23:1-8. Epub 2019 Apr 23.

a Dipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry , University of Pisa , Pisa , Italy.

Objectives: Ethnicity represents a crucial factor in influencing response to psychotropic drugs. Some data indicate that functional polymorphisms of two candidate genes of the serotonin (5-HT) transporter (SERT) may affect the response to selective 5-HT reuptake inhibitors (SSRIs). The present study aimed to compare the platelet SERT, through the specific [H]paroxetine ([H]Par) binding, and plasma oxytocin (OT) levels in 20 Senegalese and in 20 Italian men. Read More

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http://dx.doi.org/10.1080/15622975.2019.1583373DOI Listing

A simple method to estimate noise levels in the workplace based on self-reported speech communication effort in noise.

Int J Audiol 2019 Apr 23:1-4. Epub 2019 Apr 23.

e Institute of Sound and Vibration Research , University of Southampton , Southampton , UK.

Objective: To validate a method using self-reported speech communication effort in noise to estimate occupational noise levels by comparing with measured noise levels.

Design: A comparative observational study. Reported vocal effort to communicate with a person at a distance of 1. Read More

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http://dx.doi.org/10.1080/14992027.2019.1600203DOI Listing

A study on the effect of nutrient intake on the body mass index of mothers of children with food allergies.

Asian Pac J Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Department of Pediatrics, Osaka Prefecture Medical Center for Respiratory and Allergic Diseases, 3-7-1, Habikino, Habikino, Osaka Prefecture, 583-8588, Japan.

Background: No previous studies have reported the effect of the presence of children with food allergies (FAs) on the diet and body mass index (BMI) of mothers. Therefore, we conducted a dietary survey and considered nutrients that influenced BMI of mothers.

Objective: Subjects included 554 mothers-305 mothers of children with FAs (FA mothers; aged 38. Read More

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http://dx.doi.org/10.12932/AP-260718-0377DOI Listing

Evaluation of sleep quality in adolescent patients with osteosarcoma using Pittsburgh Sleep Quality Index.

Eur J Cancer Care (Engl) 2019 Apr 23:e13065. Epub 2019 Apr 23.

Department of Orthopedic Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

The sleep quality of patients with osteosarcoma (OS) was poorly understood. We aimed to evaluate the prevalence of sleep dysfunction in adolescent patients with OS using the Pittsburgh Sleep Quality Index (PSQI) and to further investigate the psychometric properties of the PSQI in this cohort of patients. Fifty four adolescent patients with OS who underwent chemotherapy treatment in our clinic centre were included. Read More

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http://dx.doi.org/10.1111/ecc.13065DOI Listing

An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows.

J Vet Pharmacol Ther 2019 Apr 23. Epub 2019 Apr 23.

Institute of Computational Comparative Medicine (ICCM), Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas.

Penicillin G is widely used in food-producing animals at extralabel doses and is one of the most frequently identified violative drug residues in animal-derived food products. In this study, the plasma pharmacokinetics and tissue residue depletion of penicillin G in heavy sows after repeated intramuscular administrations at label (6.5 mg/kg) and 5 × label (32. Read More

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http://dx.doi.org/10.1111/jvp.12766DOI Listing

Exploring patient perspectives of prediabetes and diabetes severity: a qualitative study.

Psychol Health 2019 Apr 23:1-14. Epub 2019 Apr 23.

e Family Medicine , Uniformed Services University of the Health Sciences , Bethesda , MD , USA.

Objective: This qualitative study sought to identify and describe patients' variant perceptions of disease severity after receiving a type 2 diabetes (T2DM) or prediabetes (preDM) diagnosis.

Design: Researchers interviewed 29 patients from two US medical centers to ascertain perceptions of severity. We used the constant comparative method from a grounded theory approach to identify themes from patients' perspectives that inform their disease severity. Read More

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http://dx.doi.org/10.1080/08870446.2019.1604955DOI Listing

Mediterranean versus Western Diet Effects on Caloric Intake, Obesity, Metabolism, and Hepatosteatosis in Nonhuman Primates.

Obesity (Silver Spring) 2019 May;27(5):777-784

Department of Pathology and Comparative Medicine, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.

Objective: This study aimed to determine the effects of humanlike Western and Mediterranean diets on caloric intake, obesity, metabolism, and hepatosteatosis in an established nonhuman primate model of obesity, cardiometabolic syndrome, type 2 diabetes, and atherosclerosis.

Methods: A 38-month, randomized, preclinical, nonhuman primate primary prevention trial of 38 socially housed, middle-aged adult females was conducted. The monkeys were characterized during a 7-month baseline phase while consuming chow and then randomized to either Western or Mediterranean diets; the groups were balanced on baseline characteristics. Read More

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http://dx.doi.org/10.1002/oby.22436DOI Listing

X-linked cutaneous mosaicism in a dog.

Vet Dermatol 2019 Apr 22. Epub 2019 Apr 22.

Institute of Genetics, Vetsuisse Faculty, University of Bern, 3001, Bern, Switzerland.

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http://dx.doi.org/10.1111/vde.12748DOI Listing

Partners' experiences of living with a person with an eating disorder: A grounded theory study.

J Adv Nurs 2019 Apr 22. Epub 2019 Apr 22.

Department of Nursing and Midwifery, Trinity College Dublin, Ireland.

Aim: To explore the experiences of intimate partners of people with an eating disorder.

Design: Qualitative grounded theory study.

Methods: In-depth interviews were conducted with 18 partners of people with an eating disorder from 2013 - 2016. Read More

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http://dx.doi.org/10.1111/jan.14032DOI Listing

A bridge too far in naming species: A total evidence approach does not support recognition of four species inDesertifilum (Cyanobacteria).

J Phycol 2019 Apr 23. Epub 2019 Apr 23.

Departamento de Procesos y Tecnología, Universidad Autónoma Metropolitana-Cuajimalpa, Cuajimalpa, Av. Vasco de Quiroga 4871, C.P. 05300, Ciudad de México, México.

A population of Desertifilum (Cyanobacteria, Oscillatoriales) from an oligotrophic desertic biotope was isolated and characterized using a polyphasic approach including molecular, morphological, and ecological information. The population was initially assumed to be a new species based on ecological and biogeographic separation from other existing species, however, phylogenetic analyses based on sequences of the 16S rRNA gene and 16S-23S ITS region, placed this strain clearly within the type species, Desertifilum tharense. Comparative analysis of morphology, 16S rRNA gene similarity, 16S-23S ITS secondary structure, and percent dissimilarity of the ITS regions for all characterized strains supports placing the six Desertifilum strains (designated as PD2001/TDC17, UAM-C/S02, CHAB7200, NapGTcm17, IPPAS B-1220, and PMC 872. Read More

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http://dx.doi.org/10.1111/jpy.12867DOI Listing

Comparative fatty acids composition and cholesterol content in Bactrian (Camelus bactrianus) and dromedary camel (Camelus dromedarius) meat.

Trop Anim Health Prod 2019 Apr 22. Epub 2019 Apr 22.

Al-Farabi Kazakh National University, 71 av. Al-Farabi, Almaty, Kazakhstan, 050040.

The present study is aimed at comparing the fatty acid profiles, cholesterol, and atherogenicity index of Bactrian and dromedary camel meat by using discriminant analysis to identify the more discriminating fatty acids. Six muscles were sampled from nine Bactrian and nine dromedary camels and analyzed for fatty acid parameters and cholesterol content. The mean fatty acid profiles differed in higher proportion between species than between muscles. Read More

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http://dx.doi.org/10.1007/s11250-019-01894-2DOI Listing

Genome-Wide Identification and Comparative Expression Profile Analysis of the Long-Chain Acyl-CoA synthetase (LACS) Gene Family in Two Different Oil Content Cultivars of Brassica napus.

Biochem Genet 2019 Apr 22. Epub 2019 Apr 22.

Chongqing Engineering Research Center for Rapeseed, College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, China.

Long-chain acyl-CoA synthetase (LACS) is one of the key enzymes involved in fatty acid metabolism, including phospholipid biosynthesis, triacylglycerol (TAG) biosynthesis, and fatty acid β-oxidation in plants. However, the characterization of LACSs family in seed oil biosynthesis of Brassica napus (B. napus) remains unknown. Read More

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http://link.springer.com/10.1007/s10528-019-09921-5
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http://dx.doi.org/10.1007/s10528-019-09921-5DOI Listing
April 2019
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Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex.

Chromosome Res 2019 Apr 23. Epub 2019 Apr 23.

Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA.

Canine histiocytic malignancies (HM) are rare across the general dog population, but overrepresented in certain breeds, such as Bernese mountain dog and flat-coated retriever. Accurate diagnosis relies on immunohistochemical staining to rule out histologically similar cancers with different prognoses and treatment strategies (e.g. Read More

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http://dx.doi.org/10.1007/s10577-019-09606-0DOI Listing

Genome sequencing and characterization of three Bacillus cereus-specific phages, DK1, DK2, and DK3.

Arch Virol 2019 Apr 22. Epub 2019 Apr 22.

Department of Food Science & Technology, Jinan University, Huangpu Ave. 601, Guangzhou, 510632, China.

In the study, three Bacillus cereus-specific phages, named DK1, DK2 and DK3, belonging to the family Podoviridae, were isolated from Pearl River water and sludge in Guangzhou, China. The genomes of DK1, DK2 and DK3 were 27,180 bp, 26,357 bp, and 26,865 bp in length and contained 49, 45 and 46 open reading frames, respectively. Among the three phages, DK2 shared the highest genome sequence similarity (96% identity) with DK3. Read More

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http://dx.doi.org/10.1007/s00705-019-04258-1DOI Listing

Qualitative and quantitative variations in liver function thresholds among clinical trials in cancer: a need for harmonization.

Cancer Chemother Pharmacol 2019 Apr 22. Epub 2019 Apr 22.

Division of Hematology-Oncology, Tufts Medical Center, Boston, MA, 02111, USA.

Purpose: The liver is critically involved in drug metabolism pathways and the potential for hepatic toxicity is significant with specific cancer therapeutics. Variations in the definition of liver function thresholds that may generate heterogeneity of toxicity and efficacy outcomes across therapeutics trials in cancer require assessment.

Methods: A random sample of therapeutic trials in cancer (n = 500, general category), trials using hepatotoxic drugs (abiraterone, pazopanib: n = 181), trials using drugs metabolized by the liver (doxorubicin, vincristine: n = 606), and therapeutic trials in hepatic dysfunction (n = 49) were each identified on clinicaltrials. Read More

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http://link.springer.com/10.1007/s00280-019-03821-6
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http://dx.doi.org/10.1007/s00280-019-03821-6DOI Listing
April 2019
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The environmental obesogen bisphenol A increases macrophage self-renewal.

Cell Tissue Res 2019 Apr 22. Epub 2019 Apr 22.

Institute of Neurobiology, University of Ulm, Albert-Einstein-Allee, 11 89081, Ulm, Germany.

Self-renewal of macrophages is important for the healthy development and replenishment of tissue-resident macrophage pools. How this mechanism is controlled by endocrine signals is still largely unexplored. Here, we show that the endocrine disruptor bisphenol A (BPA) increases macrophage self-renewal. Read More

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http://dx.doi.org/10.1007/s00441-019-03019-5DOI Listing

Metagenome to phenome approach enables isolation and genomics characterization of Kalamiella piersonii gen. nov., sp. nov. from the International Space Station.

Appl Microbiol Biotechnol 2019 Apr 23. Epub 2019 Apr 23.

Jet Propulsion Laboratory, Biotechnology and Planetary Protection Group, M/S 89-2, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA, 91109, USA.

Several evolutionarily distinct, near full-length draft metagenome-resolved genomes (MRG), were assembled from sequences recovered from the International Space Station (ISS) environments. The retrieval of MRGs facilitated the exploration of a large collection of archived strains (~ 500 isolates) and assisted in isolating seven related strains. The whole genome sequences (WGS) of seven ISS strains exhibited 100% identity to the 4. Read More

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http://dx.doi.org/10.1007/s00253-019-09813-zDOI Listing

Ultrasound assisted batch operation for the adsorption of hexavalent chromium onto engineered nanobiocomposite.

Heliyon 2019 Apr 12;5(4):e01491. Epub 2019 Apr 12.

Department of Chemistry, University of Kalyani, Kalyani 741235, West Bengal, India.

The study demonstrates the comparative retention characteristics of chromium from aqueous environment on iron(III) cellulose nanocomposite bead under conventional (C-ads) and ultrasound assisted (U-ads) batch adsorption operation. Optimization of process parameters was achieved varying pH, contact/sonication time, initial Cr(VI) concentration, adsorbent dose at fixed solution temperature. Equilibrium was achieved within 5 h and 30 min of contact time in C-ads and U-ads respectively. Read More

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http://dx.doi.org/10.1016/j.heliyon.2019.e01491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465586PMC

Comparison between Roche Integra 400 plus and Abbott Architect ci8200 in Alanine aminotransferase assay.

Pract Lab Med 2019 May 22;15:e00121. Epub 2019 Mar 22.

Central Laboratory of Mohammed VI University Hospital of Oujda City, Morocco.

Background: The aim of this work is to present the results of a comparative study between the ALT assay on Integra 400 plus Roche Diagnostic versus Architect ci8200 of Abbott Diagnostic.

Methods: A total of 200 patients hospitalized in the various departments of the university hospital Mohammed VI of Oujda were prospectively tested on two systems: Abbott Architect ci8200 and Roche Integra 400 plus. Both analyzers use the spectrophotometric technique by coupling the transamination reaction to the oxidation-reduction reaction at NAD. Read More

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http://dx.doi.org/10.1016/j.plabm.2019.e00121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462767PMC

Enantioselective Box Behenken Optimized HPLC-DAD Method for the Simultaneous Estimation of Alogliptin Enantiomorphs in Pharmaceutical Formulations and their Pharmacokinetic Study in Rat Plasma.

Adv Pharm Bull 2019 Feb 21;9(1):147-158. Epub 2019 Feb 21.

Pharmaceutical Chemistry Department, Delhi Institute of Pharmaceutical Sciences & Research, University of Delhi, Sector 3 Pushp Vihar, Mehrauli Badarpur Road, New Delhi -110017, India.

A stereoselective high performance liquid chromatographic analytical method with photodiode array detector was developed and validated as per the International Conference on Harmonization (ICH) guidelines for the determination of alogliptin (ALO) enantiomers in formulations and rat plasma. Enantiomeric separation was performed on a Phenomenex Lux Cellulose-2 chiral column. Box-Behnken design was used to identify the optimum conditions of the three independent variables for the desired output responses. Read More

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http://dx.doi.org/10.15171/apb.2019.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468233PMC
February 2019

In Silico Exploration of Aryl Halides Analogues as Checkpoint Kinase 1 Inhibitors by Using 3D QSAR, Molecular Docking Study, and ADMET Screening.

Adv Pharm Bull 2019 Feb 21;9(1):84-92. Epub 2019 Feb 21.

Faculty of Science, Moulay Ismail University, Meknes, Morocco.

In this review, a set of aryl halides analogs were identified as potent checkpoint kinase 1 (Chk1) inhibitors through a series of computer-aided drug design processes, to develop models with good predictive ability, highlight the important interactions between the ligand and the Chk1 receptor protein and determine properties of the new proposed drugs as Chk1 inhibitors agents. Three-dimensional quantitative structure-activity relationship (3D-QSAR) modeling, molecular docking and absorption, distribution, metabolism, excretion and toxicity (ADMET) approaches are used to determine structure activity relationship and confirm the stable conformation on the receptor pocket. The statistical analysis results of comparative -molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) models that employed for a training set of 24 compounds gives reliable values of Q (0. Read More

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https://apb.tbzmed.ac.ir/Abstract/apb-19609
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http://dx.doi.org/10.15171/apb.2019.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468235PMC
February 2019
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Quantitative genetics of gastrointestinal strongyle burden and associated body condition in feral horses.

Int J Parasitol Parasites Wildl 2019 Aug 6;9:104-111. Epub 2019 Apr 6.

Department of Ecosystem and Public Health, University of Calgary, 3280 Hospital Drive, Calgary, AB, T2N 4Z6, Canada.

Variability in host resistance or tolerance to parasites is nearly ubiquitous, and is of key significance in understanding the evolutionary processes shaping host-parasite interactions. While ample research has been conducted on the genetics of parasite burden in livestock, relatively little has been done in free-living populations. Here, we investigate the sources of (co)variation in strongyle nematode faecal egg count (FEC) and body condition in Sable Island horses, a feral population in which parasite burden has previously been shown to negatively correlate with body condition. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132244183014
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http://dx.doi.org/10.1016/j.ijppaw.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462499PMC

Artificially decreased dissolved oxygen increases the persistence of in water.

Int J Parasitol Parasites Wildl 2019 Aug 7;9:100-103. Epub 2019 Apr 7.

Department of Biomedical and Diagnostic Sciences, University of Tennessee College of Veterinary Medicine, 2407 River Drive, Knoxville, TN, 37996, USA.

Water containing organic material has been shown to increase the persistence of the avian pathogenic protozoa, . We hypothesized that the decrease in dissolved oxygen due to microbes in the organic material could increase persistence of the microaerophilic trichomonads. Using simulated birdbaths, we determined 1) the levels of dissolved oxygen in distilled water with various amounts of organic material, 2) the concentration of the oxygen-scavenging enzyme Oxyrase needed to achieve the dissolved oxygen levels obtained in organic material contaminated water, and finally, 3) the persistence of two isolates in Oxyrase®-supplemented water. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2019.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463543PMC

Hemostatic Abnormality and Associated Factors in Diabetic Patients at Jimma University Specialized Hospital, Jimma, Southwest Ethiopia: A Comparative Cross-sectional Study.

Ethiop J Health Sci 2019 Mar;29(2):251-258

School of Medical Laboratory Sciences, Jimma University, Jimma, Ethiopia.

Background: Diabetes mellitus is a group of heterogeneous disorders of multiple etiologies characterized by chronic hyperglycemia resulting from defects in insulin secretion and/or insulin action. Diabetes mellitus has been reported to disturb normal hemostasis by various mechanisms. However, data on hemostasis of diabetic patients in the study area are lacking. Read More

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http://dx.doi.org/10.4314/ejhs.v29i2.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460446PMC

Haematological traits co-vary with migratory status, altitude and energy expenditure: a phylogenetic, comparative analysis.

Sci Rep 2019 Apr 23;9(1):6351. Epub 2019 Apr 23.

Department of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5A 1S6, Canada.

Aerobic capacity is assumed to be a main predictor of workload ability and haematocrit (Hct) and haemoglobin (Hb) have been suggested as key determinants of aerobic performance. Intraspecific studies have reported increases in Hct and Hb in response to increased workload. Furthermore, Hct and Hb vary markedly among individuals and throughout the annual cycle in free-living birds and it has been suggested that this variation reflects adaptive modulation of these traits to meet seasonal changes in energy demands. Read More

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http://www.nature.com/articles/s41598-019-42921-4
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http://dx.doi.org/10.1038/s41598-019-42921-4DOI Listing

[Comparative analysis of the nutritional quality of products intended for public children against public adult from packaging].

Rev Esp Salud Publica 2019 Feb 28;93. Epub 2019 Feb 28.

Instituto de Investigación Sanitaria del Principado de Asturias. Grupo de Comportamiento Suicida y Salud Pública (CSSP). Oviedo. España.

Objective: Food advertising to attract children has always been the order of the day for industries. In recent years, due to the epidemic of childhood obesity in developed countries, legislation is increasingly strict in this regard. The purpose of this study is to compare the products targeted in their labeling to children with other similar products that do not include childish advertising to assess whether there are nutritional differences between them. Read More

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February 2019

Specific function and modulation of teleost monocytes/macrophages: polarization and phagocytosis.

Zool Res 2019 May 28;40(3):146-150. Epub 2019 Mar 28.

Laboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo Zhejiang 315211, China.

Macrophages exist in most tissues and play a variety of functions in vertebrates. Teleost fish species are found in most aquatic environments throughout the world and are quite diverse for a group of vertebrate animals. Due to whole genome duplication and environmental adaptation, teleost monocytes/macrophages possess a variety of different functions and modulations compared with those of mammals. Read More

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http://dx.doi.org/10.24272/j.issn.2095-8137.2019.035DOI Listing

A comparative study of carcass characteristics and meat quality in genetic resources Pekin ducks and commercial crossbreds.

Asian-Australas J Anim Sci 2019 Feb 14. Epub 2019 Feb 14.

Department of Animal Sciences, Faculty of Animal Science and Biology, UTP University of Science and Technology, Bydgoszcz 85084, Poland.

Objective: The study was aimed to compare carcass traits, physicochemical and textural properties of meat in two different genotypes of Pekin ducks with regard to sex effect.

Methods: The study involved 120 Pekin ducks - 30 males and 30 females of strain P33 (Polish native Pekin ducks) and 30 males and 30 females of Star 53 HY (commercial hybrid Pekin ducks). At 49 d of age, 48 birds (12 males and 12 females of each genotype) were selected for dissection. Read More

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http://dx.doi.org/10.5713/ajas.18.0790DOI Listing
February 2019

Transdifferentiation of bovine epithelial towards adipocytes in the presence of myoepithelium.

Asian-Australas J Anim Sci 2019 Apr 15. Epub 2019 Apr 15.

Department of Veterinary Surgery and Radiology, Faculty of Veterinary and Animal Sciences, Institute of Agricultural Sciences, Banaras Hindu University,Varanasi-221005, Uttar Pradesh, India.

Orchastric changes in the mammary glands are vital, especially during the lactaction. The secretary epithelial cells together with the supporting myoepithelial and stromal cells function cordially to secrete milk.Increase in the number of luminal epithelial cells and a decrease in adipocytes are visible during lactation, whereas the reverse happens in the involution. Read More

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http://dx.doi.org/10.5713/ajas.18.0806DOI Listing

Serum and Urine Albumin and Response to Loop Diuretics in Heart Failure.

Clin J Am Soc Nephrol 2019 Apr 22. Epub 2019 Apr 22.

Department of Internal Medicine, Section of Cardiovascular Medicine,

Background And Objectives: Diuretic resistance can limit successful decongestion of patients with heart failure. Because loop diuretics tightly bind albumin, low serum albumin and high urine albumin can theoretically limit diuretic delivery to the site of action. However, it is unknown if this represents a clinically relevant mechanism of diuretic resistance in human heart failure. Read More

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http://dx.doi.org/10.2215/CJN.11600918DOI Listing

Advancing the therapeutic potential of indoleamides for tuberculosis.

Antimicrob Agents Chemother 2019 Apr 22. Epub 2019 Apr 22.

Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Indole-2-carboxamide derivatives are inhibitors of MmpL3, the cell wall associated mycolic acid transporter of (Mtb). In the present study, we characterized indoleamide effects on bacterial cell morphology and re-evaluated pharmacokinetics and efficacy using an optimized oral formulation. Morphologically, indoleamide-treated Mtb cells demonstrated significantly higher numbers of dimples near the poles or septum, which may serve as the mechanism of cell death for this bactericidal scaffold. Read More

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http://dx.doi.org/10.1128/AAC.00343-19DOI Listing

Information infrastructure and quality person-centred support in supported accommodation: An integrative review.

Patient Educ Couns 2019 Mar 22. Epub 2019 Mar 22.

Graduate School of Health, University of Technology, Sydney, Australia. Electronic address:

Objectives: To integrate findings on the information infrastructure for people with intellectual or developmental disability (I/DD) living in supported accommodation, to understand how documentation use impacts person-centred support.

Methods: We conducted an integrative literature review. Following screening by two independent reviewers, we included English language peer-reviewed empirical studies (n = 34) on documentation use for people with I/DD in domestic-scale supported accommodation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07383991183077
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http://dx.doi.org/10.1016/j.pec.2019.03.008DOI Listing

Prophylactic antibiotic regimens in dental implant failure: A systematic review and meta-analysis.

J Am Dent Assoc 2019 Apr 19. Epub 2019 Apr 19.

Background: In this systematic review and meta-analysis, the authors examine the efficacy of antibiotic prophylaxis (AP) and specific antibiotic regimens for prevention of dental implant failure in patients who are healthy overall.

Types Of Studies Reviewed: The authors independently conducted electronic database and manual searches to identify randomized controlled trials (RCTs). The authors selected articles on the basis of eligibility criteria and assessed for risk of bias by using the Cochrane Handbook. Read More

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http://dx.doi.org/10.1016/j.adaj.2018.10.015DOI Listing

Late Middle Pleistocene hominin teeth from Tongzi, southern China.

J Hum Evol 2019 May 28;130:96-108. Epub 2019 Mar 28.

Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), Paseo de la Sierra de Atapuerca s/n, 09002, Burgos, Spain; UCL Anthropology, 14 Taviton Street, WC1H 0BW, London, UK.

In 1972 and 1983, four hominin teeth were recovered from Yanhui Cave, Tongzi, southern China and assigned to later Homo erectus or archaic Homo sapiens. The teeth can be dated to approximately 172,000-240,000 years before present. Here, in addition to the standard morphological comparisons, we reevaluate the morphology of the hominin teeth using geometric morphometric analyses and micro-computed tomography (micro-CT) scans. Read More

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http://dx.doi.org/10.1016/j.jhevol.2019.03.001DOI Listing

Speeding in the slow lane: Phylogenetic comparative analyses reveal that not all human life history traits are exceptional.

J Hum Evol 2019 May 9;130:36-44. Epub 2019 Mar 9.

Department of Evolutionary Anthropology, Duke University, 108 Biological Sciences Building, Campus Box 90383, Durham, NC 27708-9976, USA; Duke Global Health Institute, Duke University, 310 Trent Drive, Durham, NC 27710, USA.

Humans are thought to exhibit an unusual suite of life history traits relative to other primates, with a longer lifespan, later age at first reproduction, and shorter interbirth interval. These assumptions are key components of popular hypotheses about human life history evolution, but they have yet to be investigated phylogenetically. We applied two phylogenetic comparative methods to investigate whether these human life history traits differ from expectations based on other primates: one fits and selects between Brownian and Ornstein-Uhlenbeck models of trait evolution; the other tests for phylogenetic outliers by predicting phenotypic characteristics based on trait covariation and phylogeny for a species of interest. Read More

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http://dx.doi.org/10.1016/j.jhevol.2018.12.007DOI Listing

Vascular repair after firearm injury is associated with increased morbidity and mortality.

J Vasc Surg 2019 May;69(5):1524-1531.e1

Center for Clinical Translational Epidemiology and Comparative Effectiveness Research, Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Mass. Electronic address:

Objective: Firearm injuries have high morbidity and mortality. Presentation of injuries requiring concurrent vascular repair and its outcomes are unclear. Our study's objective was to characterize the injury details and to assess the associated mortality and morbidity after vascular repair. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.07.081DOI Listing

A prospective randomized comparative study on 60 Indian patients of melasma, comparing pixel Q-switched NdYAG (1064 nm), super skin rejuvenation (540 nm) and ablative pixel erbium YAG (2940 nm) lasers, with a review of the literature.

J Cosmet Laser Ther 2019 Apr 23:1-11. Epub 2019 Apr 23.

a Department of Dermatology and Aesthetic Surgery , Aura Skin Institute , Chandigarh , India.

Background: Treating melasma is a challenge due to suboptimal efficacy and recurrence encountered with most modalities. There is inadequate literature regarding the use of lasers for melasma in Indian skin. We compared three modalities SSR (Super Skin Rejuvenation 540 nm), PQSNDY (pixel Q-switched Nd: YAG 1064 nm), and ablative pixel-Er: YAG (2940 nm) laser in melasma, amongst Indian patients. Read More

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http://dx.doi.org/10.1080/14764172.2019.1605447DOI Listing

A Loop-Mediated Isothermal Amplification Assay for Rapid Detection of that Causes Soft Rot in Konjac.

Int J Mol Sci 2019 Apr 19;20(8). Epub 2019 Apr 19.

The Key Lab of Plant Pathology of Hubei Province, Huazhong Agricultural University, Wuhan 430070, China.

Bacterial soft rot caused by species is a serious disease in konjac (), a healthy source of starch particularly in East Asia. An effective diagnostic method is crucial to control the disease and reduce losses in konjac production. In this study, we evaluated a loop-mediated isothermal amplification (LAMP) assay with a specific primer set for the rapid and accurate detection of . Read More

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http://dx.doi.org/10.3390/ijms20081937DOI Listing

Broad Environmental Tolerance for a Host-Phage Pair Isolated from the Cargill Solar Saltworks, Newark, CA, USA.

Microorganisms 2019 Apr 19;7(4). Epub 2019 Apr 19.

Department of Biological Sciences, California State University, Long Beach, CA 90840, USA.

Phages greatly influence the ecology and evolution of their bacterial hosts; however, compared to hosts, a relatively low number of phages, especially halophilic phages, have been studied. This study describes a comparative investigation of physicochemical tolerance between a strain of the halophilic bacterium, , isolated from the Cargill Saltworks (Newark, CA, USA) and its associated phage. The host grew in media between pH 6-8. Read More

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http://dx.doi.org/10.3390/microorganisms7040106DOI Listing

Comparative Study of Phenolic Profiles, Antioxidant and Antiproliferative Activities in Different Vegetative Parts of Ramie ( L.).

Molecules 2019 Apr 19;24(8). Epub 2019 Apr 19.

Department of Food Science, Stocking Hall, Cornell University, Ithaca, NY 14853, USA.

Ramie ( L.) is usually cultivated as a fiber crop, but it is also well known for its potential use in animal feeding with viable commercial applications. In this study, the phenolics profile as well as cellular antioxidant and antiproliferative activities were investigated in free and bound fractions of six different vegetative parts from L. Read More

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http://dx.doi.org/10.3390/molecules24081551DOI Listing

Novel Molecular Signatures in the PIP4K/PIP5K Family of Proteins Specific for Different Isozymes and Subfamilies Provide Important Insights into the Evolutionary Divergence of this Protein Family.

Genes (Basel) 2019 Apr 21;10(4). Epub 2019 Apr 21.

Department of Biochemistry and Biomedical Sciences McMaster University, Hamilton, ON L8N 3Z5, Canada.

Members of the PIP4K/PIP5K family of proteins, which generate the highly important secondary messenger phosphatidylinositol-4,5-bisphosphate, play central roles in regulating diverse signaling pathways. In eukaryotic organisms, multiple isozymes and subfamilies of PIP4K/PIP5K proteins are found and it is of much interest to understand their evolution and species distribution and what unique molecular and biochemical characteristics distinguish specific isozymes and subfamilies of proteins. We report here the species distribution of different PIP4K/PIP5K family of proteins in eukaryotic organisms and phylogenetic analysis based on their protein sequences. Read More

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http://dx.doi.org/10.3390/genes10040312DOI Listing

Recognition of Emotion Intensities Using Machine Learning Algorithms: A Comparative Study.

Sensors (Basel) 2019 Apr 21;19(8). Epub 2019 Apr 21.

Electrical Engineering and Computer Science Department, The University of Toledo, 2801 W Bancroft St, MS 308, Toledo, OH 43606, USA.

Over the past two decades, automatic facial emotion recognition has received enormous attention. This is due to the increase in the need for behavioral biometric systems and human-machine interaction where the facial emotion recognition and the intensity of emotion play vital roles. The existing works usually do not encode the intensity of the observed facial emotion and even less involve modeling the multi-class facial behavior data jointly. Read More

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http://dx.doi.org/10.3390/s19081897DOI Listing

Defining the Genetic Basis of Plant⁻Endophytic Bacteria Interactions.

Int J Mol Sci 2019 Apr 20;20(8). Epub 2019 Apr 20.

Department of Plant Anatomy and Cytology, Faculty of Biology and Environmental Protection, University of Silesia in Katowice, 40-032 Katowice, Poland.

Endophytic bacteria, which interact closely with their host, are an essential part of the plant microbiome. These interactions enhance plant tolerance to environmental changes as well as promote plant growth, thus they have become attractive targets for increasing crop production. Numerous studies have aimed to characterise how endophytic bacteria infect and colonise their hosts as well as conferring important traits to the plant. Read More

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http://dx.doi.org/10.3390/ijms20081947DOI Listing
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