2,033,235 results match your criteria Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology [Journal]


Comparative Analysis of the Exposure and Surgical Freedom of the Endoscopic Extended Minipterional Craniotomy and the Transorbital Endoscopic Approach to the Anterior and Middle Cranial Fossae.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: Numerous minimally invasive approaches to the skull base have been successively developed. Knowledge of the surgical nuances of a specific approach may facilitate approach selection. This study sought to compare the nuances of an extended version of the minipterional craniotomy (EMPT) with those of the transorbital endoscopic approach (TOEA) to the anterior and middle cranial fossae (ACF and MCF, respectively). Read More

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December 2018

Comparative immunogenicity of enhanced seasonal influenza vaccines in older adults: a systematic review and meta-analysis.

J Infect Dis 2018 Dec 14. Epub 2018 Dec 14.

Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Introduction: A number of enhanced influenza vaccines have been developed for use in older adults, including the high-dose, MF59-adjuvanted, and intradermal vaccines.

Methods: We conducted a systematic review examining the improvements in antibody responses measured by the hemagglutination inhibition (HAI) assay associated with these enhanced vaccines, compared to each other, and compared to standard-dose vaccine using random effects models.

Results: Thirty-nine trials were included. Read More

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December 2018

A comparative study of thermal stability of TNT, RDX, CL20 and ANTA explosives using UV 266nm-time resolved photoacoustic pyrolysis technique.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Dec 6;211:212-220. Epub 2018 Dec 6.

Advanced Centre of Research in High Energy Materials (ACRHEM), University of Hyderabad, 500046, India. Electronic address:

The paper reports the potential use of UV based pulsed photoacoustic spectroscopy to study the thermal stability of some well-known premier explosives such as TNT, RDX, CL20, and ANTA between 30 and 350°C range. The thermal PA spectra of samples were recorded using fourth harmonic wavelength i.e. Read More

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December 2018

When is a "cryptic" species not a cryptic species: A consideration from the Holarctic micro-landsnail genus Euconulus (Gastropoda: Stylommatophora).

Mol Phylogenet Evol 2018 Dec 11. Epub 2018 Dec 11.

Department of Botany and Zoology, Masaryk University, Kotlářská 2, CZ-61137, Brno, Czechia. Electronic address:

Naive use of molecular data may lead to ambiguous conclusions, especially within the context of "cryptic" species. Here, we integrated molecular and morphometric data to evaluate phylogenetic relationships in the widespread terrestrial micro-snail genus, Euconulus. We analyzed mitochondrial (16S + COII) and nuclear (ITS1 + ITS2) sequence across 94 populations from Europe, Asia and North America within the nominate species E. Read More

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December 2018

Acoustic prepulse inhibition in male and female prairie voles: Implications for models of neuropsychiatric illness.

Behav Brain Res 2018 Dec 11. Epub 2018 Dec 11.

Oregon Health & Science University, Portland, OR, United States; VA Portland Health Care System, Portland, OR. United States. Electronic address:

Sensory gating, the ability to suppress sensory information of irrelevant stimuli, is affected in several neuropsychiatric diseases, notably schizophrenia and autism. It is currently unclear how these deficits interact with other hallmark symptoms of these disorders, such as social withdrawal and difficulty with interpersonal relationships. The highly affiliative prairie vole (Microtus ochrogaster) may be an ideal model organism to study the neurobiology underlying social behavior. Read More

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December 2018

Cellular landmarks of Trypanosoma brucei and Leishmania mexicana.

Mol Biochem Parasitol 2018 Dec 11. Epub 2018 Dec 11.

The Peter Medawar Building for Pathogen Research, University of Oxford, South Parks Road, Oxford, OX1 3SY, UK. Electronic address:

The kinetoplastids Trypanosoma brucei and Leishmania mexicana are eukaryotes with a highly structured cellular organisation that is reproduced with great fidelity in each generation. The pattern of signal from a fluorescently tagged protein can define the specific structure/organelle that this protein localises to, and can be extremely informative in phenotype analysis in experimental perturbations, life cycle tracking, post-genomic assays and functional analysis of organelles. Using the vast coverage of protein subcellular localisations provided by the TrypTag project, an ongoing project to determine the localisation of every protein encoded in the T. Read More

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December 2018

Identification of putative non-host essential genes and novel drug targets against Acinetobacter baumannii by in silico comparative genome analysis.

Microb Pathog 2018 Dec 11. Epub 2018 Dec 11.

Department of Biochemistry, Abdul Wali Khan University, Mardan, Pakistan.

Acinetobacter baumannii, the gram-negative bacteria emerged as an extremely critical pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit resistivity towards various classes of antibiotics that shows that there is a dire need to search more drug targets by exploiting the full genome of the bacteria. Read More

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December 2018

Iron-associated protein interaction networks reveal the key functional modules related to survival and virulence of Pasteurella multocida.

Microb Pathog 2018 Dec 11. Epub 2018 Dec 11.

Department of Zoology, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand; Omics Center for Agriculture, Bioresources, Food, and Health, Faculty of Science, Kasetsart University (OmiKU), Bangkok, 10900, Thailand. Electronic address:

Pasteurella multocida causes respiratory infectious diseases in a multitude of birds and mammals. A number of virulence-associated genes were reported across different strains of P. multocida, including those involved in the iron transport and metabolism. Read More

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December 2018

A scoping review to map empirical evidence regarding key domains and questions in the clinical pathway of delirium in palliative care.

J Pain Symptom Manage 2018 Dec 11. Epub 2018 Dec 11.

Division of Palliative Care, Dept of Medicine, University of Ottawa; Ottawa, ON, Canada; Bruyère Continuing Care; Ottawa, ON, Canada; Bruyère Research Institute; Ottawa, ON, Canada; Ottawa Hospital Research Institute; Ottawa, ON, Canada.

Context: Based on the clinical care pathway of delirium in palliative care (PC), a published analytic framework (AF) formulated research questions in key domains and recommended a scoping review to identify evidence gaps.

Objectives: To produce a literature map for key domains of the published AF: screening; prognosis and diagnosis; management and the health-related outcomes.

Methods: A standard scoping review framework was used by an interdisciplinary study team of nurse and physician delirium researchers, an information specialist and review methodologists to conduct the review. Read More

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December 2018

Interactions of mannose binding-lectin with red blood cells by employing cationic quantum dots.

Int J Biol Macromol 2018 Dec 11. Epub 2018 Dec 11.

Departamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil. Electronic address:

Mannose-binding lectin (MBL) plays important roles by interacting with specific molecular patterns on cell surfaces, triggering first-line host defense. We investigated the MBL interaction with healthy red blood cell membranes as well as its effects on the membrane rheology. We explored electrostatic interactions between cationic quantum dots (QDs) and negatively charged red blood cell surfaces to quantitatively evaluate membrane electrical charges as well as to investigate the MBL binding to healthy erythrocytes. Read More

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December 2018

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.

Cell 2018 Dec;175(7):1931-1945.e18

Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute (QBI), University of California San Francisco, San Francisco, CA, USA; The J. David Gladstone Institutes, San Francisco, CA, USA. Electronic address:

Mosquito-borne flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), are a growing public health concern. Systems-level analysis of how flaviviruses hijack cellular processes through virus-host protein-protein interactions (PPIs) provides information about their replication and pathogenic mechanisms. We used affinity purification-mass spectrometry (AP-MS) to compare flavivirus-host interactions for two viruses (DENV and ZIKV) in two hosts (human and mosquito). Read More

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December 2018

The Role of Common Factors in Psychotherapy Outcomes.

Annu Rev Clin Psychol 2018 Dec 14. Epub 2018 Dec 14.

Department of Clinical, Neuro-, and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, 1081 BT Amsterdam, The Netherlands; email:

Psychotherapies may work through techniques that are specific to each therapy or through factors that all therapies have in common. Proponents of the common factors model often point to meta-analyses of comparative outcome studies that show all therapies have comparable effects. However, not all meta-analyses support the common factors model; the included studies often have several methodological problems; and there are alternative explanations for finding comparable outcomes. Read More

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December 2018
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The Drying Kinetics of Salt Solution Droplets: Water Evaporation Rates and Crystallisation.

J Phys Chem B 2018 Dec 14. Epub 2018 Dec 14.

The drying and crystallisation of solution droplets is a problem of broad relevance, determining the micro-structures of particles formed in spray drying, the phase of particles delivered by, for example, aerosol formulations for inhalation therapies, and the impact of aerosols on radiative forcing and climate. The ephemeral nature of free-droplets, particularly when considering the drying kinetics of droplets with highly volatile constituents, has often precluded the accurate measurement of transient properties such as droplet size and composition, preventing the robust assessment of predictive models of droplet drying rates, nucleation and crystallisation. Here, we report novel measurements of the drying kinetics of individual aqueous sodium chloride solution droplets using a comparative-kinetics electrodynamic balance to isolate and trap single aerosol droplets (radius ~ 25 µm). Read More

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December 2018

Unbiased Measurement of Phosphate and Phosphorus Speciation in Surface Waters.

Environ Sci Technol 2018 Dec 14. Epub 2018 Dec 14.

Trace-level phosphate analysis and phosphorus speciation in surface water remained challenging due to adsorption and phosphate uptake by microorganisms. In this study a two-dimensional ion chromatography separation coupled to electrospray ionization high-resolution mass spectrometry (2D-IC-ESI-MS) allowed isotope dilution quantitation of phosphate with simultaneous analysis of eleven phosphate-containing metabolites and two inorganic condensed phosphates. Samples were collected from Lake St. Read More

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December 2018

Comparison of classical and transgenic genetic sexing strains of Mediterranean fruit fly (Diptera: Tephritidae) for application of the sterile insect technique.

PLoS One 2018 14;13(12):e0208880. Epub 2018 Dec 14.

Insect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria.

The development of genetic sexing strains (GSSs) based on classical genetic approaches has revolutionized the application of the sterile insect technique (SIT) against the Mediterranean fruit fly Ceratitis capitata (Wiedemann) (Diptera: Tephritidae). The global use of Mediterranean fruit fly GSS for SIT applications as part of area-wide integrated pest management (AW-IPM) programmes is testimony to their effectiveness. During recent years, transgenic sexing strains (TSSs) have been developed through genetic engineering techniques offering the possibility to produce male-only progeny by introducing female embryonic lethal genes and to increase the efficacy to identify released sterile males by means of the expression of fluorescent transgene markers. Read More

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December 2018

A Prospective Comparative Study Between Subcuticular and Sutureless Technique of Skin Closure Following External Dacryocystorhinostomy.

Ophthalmic Plast Reconstr Surg 2018 Dec 7. Epub 2018 Dec 7.

Orbit Oculoplasty Reconstructive and Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, India.

Purpose: To compare the cosmetic outcome of the surgical scar of external dacryocystorhinostomy by the subcuticular versus sutureless technique.

Methods: This was a prospective interventional randomized control study conducted at tertiary level hospital. Fifty patients of primary-acquired nasolacrimal duct obstruction were included in this study. Read More

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December 2018
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Comparison of Distraction Osteogenesis and Single-Stage Remodeling for Correction of Unilateral Coronal Craniosynostosis.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Division of Plastic and Reconstructive Surgery, Dalhousie University, Halifax.

Background: Unilateral coronal craniosynostosis is a challenging condition in craniofacial surgery. Frontoorbital advancement by single-stage resorbable remodeling and distraction osteogenesis (DO) techniques have known intraoperative differences, but their comparative outcomes are less well characterized.

Methods: A systematic literature search of the MEDLINE, EMBASE, LILACS, and Web of Science databases was conducted. Read More

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December 2018

Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics.

FASEB J 2018 Dec 14:fj201801843R. Epub 2018 Dec 14.

Laboratory of Bioenergetics and Biomembranes, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.

Bioenergetic failure, oxidative stress, and changes in mitochondrial morphology are common pathologic hallmarks of amyotrophic lateral sclerosis (ALS) in several cellular and animal models. Disturbed mitochondrial physiology has serious consequences for proper functioning of the cell, leading to the chronic mitochondrial stress. Mitochondria, being in the center of cellular metabolism, play a pivotal role in adaptation to stress conditions. Read More

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December 2018

[Study of cone-beam CT in evaluating the electrode array of cochlear implantation postoperatively].

Authors:
Y S Song S S Gong

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1371-1373

Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

To explore ways of evaluating morphological information of cochlea electrode in post cochlear implantation patients, and so as to make sure its value of clinical usage.A series of 52 patients who were diagnosed as severe to profound sensorineural hearing loss and received cochlear implantation were admitted. All the patients had cone-beam CT scanning of the operated side 1 or 2 days after operation. Read More

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September 2018

[The comparison of two chemiluminescent models for assessing anti-oxidative activity of blood serum of patients with liver pathology].

Klin Lab Diagn 2018 ;63(1):16-21

The Federal state budget scientifc institution "the Russian cardiologic R&D production complex" of Minzdrav of Russia, 121552, Moscow, Russia.

The comparative assessment was carried out concerning anti-oxidation activity of blood serum of patients with liver pathology using two chemiluminescent techniques with different models of free radical oxidation: «Hb-Н2О2-luminol» и «ABAP-luminol». The reliable but low correlation of results was established (r=0,798) related mainly to difference in mechanisms of initiation of free radicals and effect of blood serum on initiation process. This effect is stronger manifested in model «Hb-Н2О2-luminol». Read More

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January 2018

Comparative study between Plate-Graff, Plate-Cage and peek cage in cervical spine fusion.

Acta Ortop Mex 2018 Jul-Aug;32(4):203-208

Spine Surgery Service. National Institute of Rehabilitation Luis Guillermo Ibarra Ibarra. Mexico City. Mexico.

Objective: To compare results of Plate-Graff, Plate-Cage and PEEK cage in patients with cervical stenosis.

Material And Methods: Prospective, with before and after intervention and comparative study. From January 2005 to October 2011 we included 37 patients (male: 48. Read More

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December 2018

Relationships among general health, job satisfaction, work engagement and job features in nurses working in a public hospital: A cross-sectional study.

J Clin Nurs 2018 Dec 14. Epub 2018 Dec 14.

Multidisciplinary Group of Integral Cares (GIMCI), Av. Menéndez Pidal, s/n, 14004, Córdoba, Spain.

Aim And Objective: To describe relations among health, job satisfaction, work engagement and job features in Spanish nurses working in a public hospital.

Background: It has been established that nursing staff health affects the quality of their work and is associated with job satisfaction, work engagement and different job features. Understanding the relationships among these variables could provide useful information to improve staff performance and prevent work-related illnesses. Read More

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December 2018

Molecular cloning and comparative analysis of transcripts encoding chemosensory proteins from two plant bugs, Lygus lineolaris and Lygus hesperus.

Insect Sci 2018 Dec 13. Epub 2018 Dec 13.

USDA-ARS Arid Land Agricultural Center, Maricopa, AZ, 85138, USA.

Chemosensory proteins (CSPs) are soluble carrier proteins typically characterized by a six-helix bundle structure joined by two disulfide bridges and a conserved Cys spacing pattern (C1-X -C2-X -C3-X -C4). CSPs are functionally diverse with reported roles in chemosensation, immunity, development, and resistance. To expand our molecular understanding of CSP function in plant bugs, we used recently developed transcriptomic resources for Lygus lineolaris and Lygus hesperus to identify 17 and 14 CSP-like sequences, respectively. Read More

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December 2018

Estimating the global distribution of field size using crowdsourcing.

Glob Chang Biol 2019 Jan 22;25(1):174-186. Epub 2018 Nov 22.

International Institute for Applied Systems Analysis, ESM, Laxenburg, Austria.

There is an increasing evidence that smallholder farms contribute substantially to food production globally, yet spatially explicit data on agricultural field sizes are currently lacking. Automated field size delineation using remote sensing or the estimation of average farm size at subnational level using census data are two approaches that have been used. However, both have limitations, for example, automatic field size delineation using remote sensing has not yet been implemented at a global scale while the spatial resolution is very coarse when using census data. Read More

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January 2019

Understanding others: emotion recognition abilities in humans and other animals.

Genes Brain Behav 2018 Dec 13:e12544. Epub 2018 Dec 13.

Genetics of Cognition laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy.

Emotion recognition represents the ability to encode an ensemble of sensory stimuli providing information about the emotional state of another individual. This ability is not unique to humans. An increasing number of studies suggests that many aspects of higher order social functions, including emotion recognition, might be present in species ranging from primates to rodents, indicating a conserved role of these abilities in social animals. Read More

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December 2018

Description of Paraclostridium bifermentans subsp. muricolitidis subsp. nov., emended description of Paraclostridium bifermentans (Sasi Jyothsna et al., 2016), and creation of Paraclostridium bifermentans subsp. bifermentans subsp. nov.

Microbiol Immunol 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Microbiology, Aichi Gakuin University Graduate School of Pharmaceutical Science, 1-100 Kusumoto-cho, Nagoya, Aichi, 464-8650, Japan.

Taxonomic studies of strain PAGU 1678 , an obligately anaerobic, Gram-stain positive, spore-forming bacterium isolated from Biobreeding rat feces, were performed. This strain has been demonstrated that the ability to exacerbate pathosis in a mouse model of dextran sulfate sodium-induced ulcerative colitis. Phylogenetic analysis based on the 16S rRNA gene showed high homology with Paraclostridium bifermentans. Read More

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December 2018

Mononuclear cell collection for extracorporeal photopheresis by using the "off-line" system: A comparative study between COBE Spectra and Spectra Optia devices.

J Clin Apher 2018 Dec 14. Epub 2018 Dec 14.

Hemathology and Hemotherapy Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background: Extracorporeal photopheresis (ECP) is an efficient and established therapy to treat acute and chronic graft vs host disease (GVHD). Using an "off-line" method, the first step (mononuclear cell [MNC] collection) is decisive, as long as a high MNC yield and purity in the collected product is desirable. Two "off-line" devices were compared: the COBE Spectra and the Spectra Optia (Terumo BCT), using both continuous and intermittent protocols. Read More

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December 2018

Developmental regulation of lifelong dental experiences and beliefs in Guangzhou and Hong Kong.

Gerodontology 2018 Dec 14. Epub 2018 Dec 14.

Cooperative Research Centre for Oral Health Science Melbourne Dental School, University of Melbourne, Melbourne, Victoria, Australia.

Aims: The aim of this study was to explain through the life-course and life-span perspectives of developmental regulation theory the controls on dental experiences and beliefs throughout the lives of older people in Guangzhou and Hong Kong.

Background: Dental diseases and disabilities among older people are serious public health concerns in China.

Methods: A facilitator conducted eight focus groups, three in Hong Kong and five in Guangzhou, involving a total of 51 participants. Read More

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December 2018

Clinical effectiveness and safety of erythropoietin-stimulating agents for the treatment of low- and intermediate-1-risk myelodysplastic syndrome: a systematic literature review.

Br J Haematol 2018 Dec 13. Epub 2018 Dec 13.

Service d'Hématologie Clinique, Hôpital St. Louis and Paris 7 University, Paris, France.

Many patients with lower-risk myelodysplastic syndrome (MDS) experience anaemia, which has negative consequences. Erythropoiesis-stimulating agents (ESAs) and their biosimilars are used to treat anaemia in MDS and, currently, epoetin alfa and darbepoetin alfa are commonly used and recommended by clinical guidelines. To better understand the evidence available on the use of ESAs for anaemia in lower-risk MDS, we conducted a systematic literature review to identify randomized and nonrandomized prospective studies reporting on clinical efficacy/effectiveness, patient-reported quality of life (QoL), and safety. Read More

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December 2018

Design and validation of a "Peristomal Lesion Scale" for peristomal skin assessment.

Int Wound J 2018 Dec 13. Epub 2018 Dec 13.

Department of Molecular Medicine, University of Padova, Padova, Italy.

Many people in Italy undergo ostomy because of illness, and this can have negative psychological and physical effects. It is estimated that 15%-43% of ostomates suffer from skin complications in the peristomal area. During their life, many ostomates experience at least one peristomal lesion, and they turn to stomal therapy centres where trained nurses provide patient care and manage skin complications. Read More

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December 2018
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Comparative effectiveness of radiotherapy for early-stage hormone receptor-positive breast cancer in elderly women using real-world data.

Cancer Med 2018 Dec 12. Epub 2018 Dec 12.

Pharmaceutical Outcomes & Policy (POP), College of Pharmacy, University of Florida, Gainesville, Florida.

Background: Radiotherapy is the recommended treatment after breast-conserving surgery (BCS) for early-stage breast cancer (BC). However, there is no clear evidence whether radiotherapy after BCS improves the survival of elderly women diagnosed with early-stage hormone receptor-positive (HR+) BC. The aim of this study was to investigate the survival benefit associated with radiotherapy plus hormonal therapy vs hormonal therapy alone after BCS for early-stage HR+ BC patients. Read More

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December 2018

A New Era of Cardiac Cell Therapy: Opportunities and Challenges.

Adv Healthc Mater 2018 Dec 13:e1801011. Epub 2018 Dec 13.

Department of Molecular Biomedical Sciences and Comparative Medicine Institute, North Carolina State University, Raleigh, NC, 27607, USA.

Myocardial infarction (MI), caused by coronary heart disease (CHD), remains one of the most common causes of death in the United States. Over the last few decades, scientists have invested considerable resources on the study and development of cell therapies for myocardial regeneration after MI. However, due to a number of limitations, they are not yet readily available for clinical applications. Read More

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December 2018

Life satisfaction in children with attention deficit hyperactivity disorder: Looking beyond proxy reports.

J Child Adolesc Psychiatr Nurs 2018 Dec 12. Epub 2018 Dec 12.

Oregon Health & Science University (OSHU), La Grande Campus, Portland, Oregon.

Problem: A common clinical approach to children with attention deficit hyperactivity disorder (ADHD) is to view them through an adult-proxy report of problems. There is little evidence on how children with ADHD evaluate their life satisfaction, how their evaluations compare with unaffected children, or how their perspectives might inform clinical practice.

Methods: A parallel convergent mixed-methods design was used to interview 20 children (aged, 7-11 years) with ADHD. Read More

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December 2018

Comparative proteomics of Helicobacter pylori strains reveals geographical features rather than genomic variations.

Genes Cells 2018 Dec 12. Epub 2018 Dec 12.

Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku Kyoto, Japan, 606-8501.

Helicobacter pylori, a pathogen of various gastric diseases, has many genome sequence variants. Thus, the pathogenesis and infection mechanisms of the H. pylori-driven gastric diseases have not been elucidated. Read More

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December 2018

Radial Glia in Echinoderms.

Dev Neurobiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Biology, University of North Florida, Jacksonville, Florida.

Radial glial cells are crucial in vertebrate neural development and regeneration. It has been recently proposed that this neurogenic cell type might be older than the chordate lineage itself and might have been present in the last common deuterostome ancestor. Here, we summarize the results of recent studies on radial glia in echinoderms, a highly regenerative phylum of marine invertebrates with shared ancestry to chordates. Read More

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December 2018

Comparative assessment of the intrinsic sensitivity of crop species and wild plant species to plant protection products and their active substances, and potential implications for the risk assessment - A literature review.

Integr Environ Assess Manag 2018 Dec 12. Epub 2018 Dec 12.

tier3 solutions GmbH, Kolberger Str. 61-63, D-51381 Leverkusen, Germany.

A comprehensive critical review was undertaken aiming to compare the intrinsic sensitivity of terrestrial plant species (crop species and non-crop wild species) using published literature and unpublished proprietary data generated for the registration of plant protection products (PPPs), and a database was compiled. Data were assessed in order to answer the question whether crops differ from non-crop plants in their intrinsic sensitivity to PPPs. Endpoints were assessed considering further potentially relevant parameters by means of different methods, including a quotient approach, where overall crop-endpoints were divided by matching wild species endpoints. Read More

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December 2018

Histopathological analysis of papillary thyroid carcinoma detected during ultrasound screening examinations in Fukushima.

Cancer Sci 2018 Dec 11. Epub 2018 Dec 11.

Department of Radiation Molecular Epidemiology, Atomic Bomb Disease Institute, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.

Thyroid ultrasound screening of young residents in Fukushima prefecture of Japan demonstrated high detection rate of papillary thyroid carcinoma (PTC). Detailed morphological analysis of these tumors was not presented to date. This study sets out to evaluate changes in histopathological and invasive characteristics of Fukushima PTC with time after the nuclear accident of March 2011 in all available cases and in different age subgroups. Read More

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December 2018

Reliability, validity, and sensitivity of the Chinese Short-Form 36 Health Survey version 2 (SF-36v2) in women with breast cancer.

J Eval Clin Pract 2018 Dec 12. Epub 2018 Dec 12.

School of Nursing, Xi'an Jiaotong University Health Science Centre, Xi'an, China.

Rationale, Aims, And Objectives: The psychometrics of the Short-Form 36 Health Survey version 2 (SF-36v2) in female breast cancer patients remains unknown. This study aimed to test the reliability, validity, and sensitivity of the Chinese SF-36v2 in women with breast cancer.

Methods: The sample included 326 eligible participants. Read More

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December 2018

Influence of canine donor plasma hemostatic protein concentration on quality of cryoprecipitate.

J Vet Intern Med 2018 Dec 11. Epub 2018 Dec 11.

Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Background: Cryoprecipitate (CRYO) is a plasma component containing high concentrations of factor VIII (FVIII), von Willebrand factor (VWF), and fibrinogen. Because Greyhounds are reported to have lower plasma VWF and fibrinogen concentrations, their plasma may not yield high potency CRYO.

Objectives: To determine if plasma hemostatic protein concentration is a good predictor of CRYO potency and if a difference exists in quality of CRYO prepared from Greyhounds versus non-Greyhounds. Read More

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December 2018

Commentary on Simon et al. 2018: "Comparative economic evaluation of quetiapine plus lamotrigine combination vs quetiapine monotherapy (and folic acid vs placebo) in patients with bipolar depression (CEQUEL)".

Authors:
Denise Razzouk

Bipolar Disord 2018 Dec 11. Epub 2018 Dec 11.

Centre of Economic Mental Health, Department of Psychiatry, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.

Simon et al. conducted a 52-week prospective cost-utility analysis (CUA) of 201 people with bipolar depression to assess the add-on lamotrigine effectiveness and efficacy (CEQUEL study ) in combination with quetiapine. To that end, they compared health gain using the EuroQol 5D- 3L (EQ-5D) between a quetiapine-only and quetiapine plus lamotrigine regimen in a multi-centre randomized control CEQUEL trial conducted in the United Kingdom and Austria with a health and social care perspective. Read More

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December 2018

3D Printed Microfluidic Mixers-A Comparative Study on Mixing Unit Performances.

Small 2018 Dec 10:e1804326. Epub 2018 Dec 10.

Institute of Technical Chemistry, Leibniz University Hannover, Callinstraße 5, 30167, Hannover, Germany.

One of the basic operations in microfluidic systems for biological and chemical applications is the rapid mixing of different fluids. However, flow profiles in microfluidic systems are laminar, which means molecular diffusion is the only mixing effect. Therefore, mixing structures are crucial to enable more efficient mixing in shorter times. Read More

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December 2018

Covalent Vs Non-Covalent inhibition: Tackling Drug Resistance in EGFR - A Thorough Dynamic Perspective.

Chem Biodivers 2018 Dec 11. Epub 2018 Dec 11.

University of KwaZulu-Natal, Westville, School of Health Sciences, School of Health Sciences, University of, Not Available, 4001, Durban, SOUTH AFRICA.

A persistent challenge in the treatment of non-small cell lung cancer (NSCLC) with EGFR is the emergence of drug-resistant caused by somatic mutations. The EGFR L858R/T790M double mutant (EGFRDM) was found to be the most alarming variant. Despite the development of a wide range of inhibitors, none of them could inhibit EGFRDM effectively. Read More

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December 2018

Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study.

J Cosmet Dermatol 2018 Dec 9. Epub 2018 Dec 9.

Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Many methods have been performed to achieve a satisfying outcome in acne scars but some of them were high cost and also were associated with low results and some complications.

Objectives: To evaluate and compare the efficacy and safety therapy of glycolic acid (GA) peel, microneedling with dermapen and a combination of both procedures in treatment of atrophic acne scars.

Patents And Methods: This study was conducted on 30 patients suffering from acne scars. Read More

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December 2018

Evolution of physiotherapy scholarship: A comparative bibliometric analysis of two decades of English published work.

Physiother Res Int 2018 Dec 10:e1760. Epub 2018 Dec 10.

Executive Office, National Council of State Boards of Nursing, Chicago, IL, USA.

Objectives: To undertake a bibliometric analysis of the physiotherapy literature at two points in time to identify similarities, differences, and the evolution of scholarship over a 40-year time-frame.

Method: To undertake a quantitative comparative analysis of the published and indexed scholarship literature contained within Scopus relating to physiotherapy over two 10-year time windows-1978-1987 and 2008-2017. The method used, bibliometrics, is capable of identifying the nature of scholarship, the key actors, and how the focus and methods used to conduct studies have changed. Read More

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December 2018

Hepatitis E virus infection in swine workers: A meta-analysis.

Zoonoses Public Health 2018 Dec 10. Epub 2018 Dec 10.

Department of Epidemiology, Fudan University School of Public Health, Key Laboratory of Public Health Safety (Ministry of Education), Shanghai, China.

Hepatitis E virus (HEV) infects both humans and animals. Swine has been confirmed to be the principal natural reservoir, which raises a concern that HEV infection would be substantially increasing among swine workers. The present study calculated the pooled prevalence of IgG antibodies against HEV among swine workers and the general population in previous cross-sectional studies. Read More

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December 2018

Morphology and Phylogeny of Calyptospora paranaidji n. sp. (Eimeriorina: Calyptosporidae), an Apicomplexan Parasite of the Hepatic Tissue of Cichla piquiti Kullander & Ferreira, 2006, From a Reservoir in the Brazilian Amazon Region.

J Eukaryot Microbiol 2018 Dec 10. Epub 2018 Dec 10.

Postgraduate Program in Biology of Infectious and Parasitic Agents /, Federal University of Pará - PPgBAIP / UFPA. Research Laboratory Carlos Azevedo / Federal Rural University of the Amazon - LPCA / UFRA, Pará, Brazil.

The coccidians of the family Calyptosporidae are parasites of the tissue and organs of fish and aquatic invertebrates, in particular in the tropical region. In contrast with other apicomplexans of the suborder Eimeriorina, the diversity and ecology of the species of the genus Calyptospora have been poorly investigated, resulting in a lacuna that restricts the understanding of the distribution and prevalence of this group of eukaryote microparasites in the Amazon region. In the present study, the integrated comparative analysis of morphological characteristics, histological and structural traits, and the sequences of a fragment of the 18S rRNA gene, provides support for the identification of a new species of Calyptospora, found parasitising the hepatic tissue of the piscivorous blue peacock bass, Cichla piquiti, captured in the reservoir of the Estreito hydroelectric dam on the middle Tocantins River in northern Brazil. Read More

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December 2018
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A Comparative Analysis of the Injury Patterns and In-Hospital Mortality Rates of Belted and Unbelted Motor-Vehicle Occupants - Puerto Rico, January 2000 to December 2014.

P R Health Sci J 2018 Diciembre;37(4):213-219

Puerto Rico Trauma Hospital, Puerto Rico Medical Center, San Juan, PR; Department of Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, PR.

Objective: Motor vehicle collisions (MVCs) constitute a leading source of morbidity and mortality worldwide. Seatbelt use has been associated with reduced mortality in MVCs. In Puerto Rico, the impact of seatbelt use on MVC deaths has not been evaluated, although they represent a major public health threat. Read More

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December 2018

Oncologic outcomes in prostate cancer patients treated with robot-assisted radical prostatectomy: results from a single institution series with more than 10 years follow up.

Minerva Urol Nefrol 2018 Dec 14. Epub 2018 Dec 14.

Department of Urology, OLV Aalst, Belgium.

Background: Robot-assisted radical prostatectomy (RARP) has gained increasing diffusion as standard of care in the surgical treatment of prostate cancer (PCa) patients, even in the absence of robust long-term oncologic comparative data. To report oncologic outcomes of RARP at more than 10 years follow up.

Methods: We retrospectively evaluated 173 consecutive PCa patients underwent RARP between 2002 and 2005 at a single European center with complete clinic and pathologic data and potential follow up of at least 10 years. Read More

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December 2018

Intra-epidemic genome variation in highly pathogenic African swine fever virus (ASFV) from the country of Georgia.

Virol J 2018 Dec 14;15(1):190. Epub 2018 Dec 14.

Laboratory of the Ministry of Agriculture, Tbilisi, Georgia.

Background: African swine fever virus (ASFV) causes an acute hemorrhagic infection in suids with a mortality rate of up to 100%. No vaccine is available and the potential for catastrophic disease in Europe remains elevated due to the ongoing ASF epidemic in Russia and Baltic countries. To date, intra-epidemic whole-genome variation for ASFV has not been reported. Read More

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December 2018

Comparative dynamics of peritoneal cell immunophenotypes in sheep during the early and late stages of the infection with Fasciola hepatica by flow cytometric analysis.

Parasit Vectors 2018 Dec 14;11(1):640. Epub 2018 Dec 14.

Animal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Campus de Rabanales, Ctra. Madrid-Cádiz, km 396, 14014, Córdoba, Spain.

Background: The peritoneal cell populations (PCP) are thought to play a crucial role during the early immune response in Fasciola hepatica infection while newly excysted juveniles (NEJ) are migrating in the peritoneal cavity (PC) towards the liver. In this study, we aimed to determine the immunophenotypes of the PCP and to analyse the dynamics of the recruitment of the PCP during the early and late stage of the infection in sheep infected with F. hepatica. Read More

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December 2018
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