38,811 results match your criteria Colonoscopy


Cold snare polypectomy: indications, devices, techniques, outcomes and future.

Dig Endosc 2018 Dec 14. Epub 2018 Dec 14.

Digestive Disease Center, Showa Inan General Hospital, Komagane, Japan.

Colonoscopy has been shown to reduce the risk of colon cancer by enabling the removal of precancerous lesions. Although the cold snare and hot snare polypectomy have similar retrieval rates and complete resection rates, the rates of delayed bleeding tend to be lower with cold snare polypectomy than with hot snare polypectomy, especially for patients taking antithrombotic agents. However, among cold snares there may be differences in terms of the completeness of polyp excision, as complete removal appears more likely with thin-wire dedicated cold snares compared to the traditional, thick-wire cold snares. Read More

View Article
December 2018

Cost-effectiveness of a patient navigation intervention to increase colonoscopy screening among low-income adults in New Hampshire.

Cancer 2018 Dec 12. Epub 2018 Dec 12.

Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.

Background: Colonoscopy is the most widely used colorectal cancer (CRC) screening test in the United States. Through the detection and removal of potentially precancerous polyps, it can prevent CRC. However, CRC screening remains low among adults who are recommended for screening. Read More

View Article
December 2018

Gut microbiota in patients after surgical treatment for colorectal cancer.

Environ Microbiol 2018 Dec 10. Epub 2018 Dec 10.

Department of Oncological and Laparoscopic Surgery, the First Affiliated Hospital of Harbin Medical University, Harbin, China, 150001.

Background: Colorectal cancer (CRC) is a common disease worldwide that is strongly associated with the gut microbiota. However, little is known regarding the gut microbiota after surgical treatment.

Methods: 16S rRNA gene sequencing was used to evaluate differences in gut microbiota among colorectal adenoma patients, CRC patients, CRC postoperative patients and healthy controls by comparing gut microbiota diversity, overall composition and taxonomic signature abundance. Read More

View Article
December 2018

Necrotizing fasciitis following colonoscopy in the setting of ulcerative colitis.

ANZ J Surg 2018 Dec 9. Epub 2018 Dec 9.

Department of Plastic and Reconstructive Surgery, Peninsula Health, Melbourne, Victoria, Australia.

View Article
December 2018

An Uncommon Presentation of Leiomyoma Cecum as a Subcutaneous Abscess of the Right Flank.

Cureus 2018 Oct 9;10(10):e3432. Epub 2018 Oct 9.

Otolaryngology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Cecal leiomyomas are rare benign tumors of smooth muscle arising from the colonic muscularis mucosa or muscularis propria. They are usually asymptomatic in nature and, if symptomatic, may present as pain in the abdomen, intestinal obstruction, or bleeding. In some cases, leiomyoma can cause free perforation leading to peritonitis. Read More

View Article
October 2018
1 Read

Primary signet ring cell carcinoma of the cervix: A case report with review of the literature.

Taiwan J Obstet Gynecol 2018 Dec;57(6):862-866

Department of Obstetrics and Gynecology, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan. Electronic address:

Objective: Primary cervical signet ring cell carcinoma (PCSRCC) is extremely rare. In this paper, we describe a case presenting with PCSRCC.

Case Report: The 48-year-old woman visited the gynecological department because of postmenopausal bleeding. Read More

View Article
December 2018

Participation in a population-based screening for colorectal cancer using the faecal immunochemical test decreases mortality in 5 years.

Eur J Gastroenterol Hepatol 2018 Dec 12. Epub 2018 Dec 12.

OSTEBA, Basque Office for Health Technology Assessment, Ministry of Health, Basque Government, Vitoria-Gasteiz.

Background: The steady increase in colorectal cancer (CRC) could be reversed through timely secondary prevention (screening) as a main strategy. The aims of this study were to determine the main features of CRC, survival rate and related factors for different types of identified CRCs in a population-based screening programme using the faecal immunochemical test (FIT).

Materials And Methods: The CRCs in the susceptible population to be screened between 2009 and 2014 were identified and classified into four groups: (a) nonscreening-detected CRC (diagnosed before first screening invitation and nonparticipants), (b) screening-detected CRC, (c) interval cancer (IC) FIT (diagnosed between screening rounds after a negative FIT) and (d) IC colonoscopy (diagnosed before the colonoscopy surveillance, which is recommended after the screening colonoscopy). Read More

View Article
December 2018

Alberta Family Physician Electronic Endoscopy study: Quality of 1769 colonoscopies performed by rural Canadian family physicians.

Can Fam Physician 2018 Dec;64(12):e553-e560

Professor and Chair in the Department of Family Medicine at the University of Alberta.

Objective: To determine whether rural FP colonoscopists in Alberta are achieving benchmarks in colonoscopy quality.

Design: Prospective, multicentre observational study.

Setting: Alberta. Read More

View Article
December 2018

The novel latex agglutination turbidimetric immunoassay system for simultaneous measurements of calprotectin and hemoglobin in feces.

Intest Res 2018 Dec 14. Epub 2018 Dec 14.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Background/aims: Fecal calprotectin (Fcal) as well as the fecal immunochemical test (FIT) are useful biomarkers for detecting activity and mucosal healing in inflammatory bowel diseases. Here, we report the performance of simultaneous measurements of Fcal and FIT for ulcerative colitis (UC) patients using the newly-developed latex agglutination turbidimetric immunoassay (LATIA) system.

Methods: Fcal and hemoglobin were measured by the LATIA system in 152 UC patients who underwent colonoscopy. Read More

View Article
December 2018

Current Role of Endoscopic Ultrasonography in Rectal Cancer Evaluation During Multidisciplinary Therapy.

Curr Health Sci J 2015 Jul-Sep;41(3):259-263. Epub 2015 Mar 15.

5Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy of Craiova, Romania; Department of Endoscopy, Copenhagen University Hospital Herlev, Denmark.

We report the case of a patient presenting in the Gastroenterology Department with intermittent rectal bleeding during the past year. A diagnosis of a low rectal adenocarcinoma was based on colonoscopy examination with biopsies, and staging procedures included transrectal endoscopic ultrasonography and magnetic resonance imaging of the abdomen and pelvis (cT2N0M0). Consequently the patient was referred for pre-operative chemoradiotherapy, achieving a complete clinical response as documented by repeated EUS and MRI examinations. Read More

View Article

Increased serological, cancer-associated protein biomarker levels at diagnosis of large bowel adenoma: Risk of subsequent primary malignancy?

Acta Oncol 2018 Dec 7:1-7. Epub 2018 Dec 7.

a Department of Surgical Gastroenterology, Center for Surgical Research , Hvidovre Hospital , Hvidovre , Denmark.

Background: Blood-based, cancer-associated biomarkers may detect subjects at risk of having neoplastic diseases. The aim of the present study was to evaluate whether elevated serological protein biomarker levels may identify adenoma patients, who are at increased risk of being diagnosed with subsequent primary malignancy.

Methods: Levels of CEA, CA19-9, TIMP-1 and YKL-40 were determined in blood samples collected prior to diagnostic bowel endoscopy due to symptoms of colorectal neoplasia. Read More

View Article
December 2018

Patient-reported complications related to colonoscopy: a prospective feasibility study of an email-based survey.

Acta Oncol 2018 Dec 7:1-6. Epub 2018 Dec 7.

a Department of Surgery , Odense University Hospital , Odense, Denmark.

Objective: This prospective pilot study assessed the feasibility of electronic email-based questionnaires about patient-reported complications after colonoscopy.

Material And Methods: A newly internally validated questionnaire on patient-reported complications related to colonoscopy was conducted as an online survey.

Results: Out of 200 patients (mean age 65 years), 83% completed the first questionnaire immediately after the procedure, 77% completed the second follow-up questionnaire after 24 h at home, and 70% the third one after 30 d. Read More

View Article
December 2018

[Gastrointestinal endoscopies in the elderly].

Soins Gerontol 2018 Jul - Aug;23(132):17-20

Service de médecine gériatrique, Hupifo, site Ambroise-Paré (AP-HP), 9 avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France. Electronic address:

There are numerous indications for gastrointestinal endoscopies in elderly people. These include notably bleeding of the digestive tract, unexplained anorexia, abdominal pain, a pathology of the colon or screening for cancerous lesions. These examinations are carried out by a multidisciplinary team. Read More

View Article
December 2018

Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study.

Fam Pract 2018 Dec 12. Epub 2018 Dec 12.

The Health Improvement Institute (THIS), University of Cambridge, Cambridge, UK.

Background: Large variation in measures of diagnostic activity has been described previously between English general practices, but related predictors remain understudied.

Objective: To examine associations between general practice population and characteristics, with the use of urgent referrals for suspected cancer, and use of endoscopy.

Methods: Cross-sectional observational study of English general practices. Read More

View Article
December 2018
1.842 Impact Factor

The "Difficult" Colorectal Polyps and Adenomas: Practical Aspects.

Dig Dis 2018 Dec 12:1-6. Epub 2018 Dec 12.

Background: Colonoscopy is the gold standard for adenoma detection. All endoscopists who perform colonoscopy must by mandate be skilled to perform polypectomy. However, there are significant differences between endoscopists in terms of the polyp detection rate and in the effectiveness of polypectomy. Read More

View Article
December 2018
2 Reads

Demographic and comorbidity predictors of adherence to diagnostic colonoscopy in the Danish Colorectal Cancer Screening Program: a nationwide cross-sectional study.

Clin Epidemiol 2018 23;10:1733-1742. Epub 2018 Nov 23.

Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark,

Background: Predictors of participation in colorectal cancer screening with a stool sample screening modality have been widely studied, but adherence to subsequent diagnostic colonoscopy after a positive screening test has received less attention. We aimed to determine predictors of adherence to diagnostic colonoscopy in the Danish Colorectal Cancer Screening Program.

Methods: We conducted a cross-sectional study using data from National Health Service registries. Read More

View Article
November 2018

Bladder Invasion in Patients with Advanced Colorectal Carcinoma.

Indian J Surg Oncol 2018 Dec 23;9(4):547-551. Epub 2018 Jul 23.

5Department of Biotechnology and Microbiology, Karnatak University, Dharwad, 580003 Karnataka India.

Involvement of the bladder by colorectal cancer is sufficiently rare to be encountered by an individual surgeon on an infrequent basis. Extirpative procedures for advanced colorectal cancers can involve partial/total bladder resections. In patients without evidence of distant metastatic disease, a reasonable therapeutic effect can be expected when negative surgical margins are obtained. Read More

View Article
December 2018

Faecal immunochemical tests (FIT) versus colonoscopy for surveillance after screening and polypectomy: a diagnostic accuracy and cost-effectiveness study.

Gut 2018 Dec 11. Epub 2018 Dec 11.

Cancer Screening and Prevention Research Group (CSPRG), Department of Surgery and Cancer, Imperial College London, London, UK.

Objective: The English Bowel Cancer Screening Programme (BCSP) recommends 3 yearly colonoscopy surveillance for patients at intermediate risk of colorectal cancer (CRC) postpolypectomy (those with three to four small adenomas or one ≥10 mm). We investigated whether faecal immunochemical tests (FITs) could reduce surveillance burden on patients and endoscopy services.

Design: Intermediate-risk patients (60-72 years) recommended 3 yearly surveillance were recruited within the BCSP (January 2012-December 2013). Read More

View Article
December 2018

Contribution of the OC Sensor immunoassay in comparison to the Hemoccult II guaiac-test in organized colorectal cancer screening.

Eur J Epidemiol 2018 Dec 8. Epub 2018 Dec 8.

Service d'Hépato-gastro-entérologie, CHU Angers, 4, rue Larrey, 49933, Angers Cedex 09, France.

Colorectal cancer (CRC) is a major cause of cancer-related death of worldwide with high incidence and mortality rate, accessible to a screening program in France, first with guaiac- based fecal occult blood test (g-FOBT) then with fecal immunochemical tests (FIT), since 2015, because of better accuracy. The aim of our study was to compare the characteristics of screen-detected lesions in two successive CRC screening campaigns, using two different tests (Hemoccult II and OC Sensor) in the department of Maine-et-Loire, and to precise the performance of these tests [participation rate, detection rates (DR), positive predictive value (PPV)]. Participants, invited by CAP SANTE 49, with polyps or cancer at the colonoscopy after a positive screening test between 01/01/2013 and 31/12/2016 were included. Read More

View Article
December 2018

The role of intravenous Contrast Agent in the Sonographic Assessment of Crohn's Disease Activity: Is Contrast Agent Injection Necessary?

J Crohns Colitis 2018 Dec 8. Epub 2018 Dec 8.

Department of Radiology, Valencia (SPAIN).

Background: the literature shows that contrast-enhanced ultrasound (CEUS) is superior to wall thickness or color Doppler imaging (CDI) in predicting disease activity using endoscopy as the reference standard.

Objective: to determine in patients with Crohn´s disease (CD) whether the evaluation of wall thickness or CDI before CEUS examination could help decide when the injection of contrast agent is justified as a means for detecting disease activity as determined at endoscopy, without reducing the accuracy of ultrasound.

Material & Methods: 180 patients with CD underwent both colonoscopy and US, including mural thickness, CDI and CEUS evaluation, prospectively as part of clinical care. Read More

View Article
December 2018

[Fecal microbiota transplantation through colonoscopy for Clostridium difficile recurrent infection. Report of eight cases].

Rev Med Chil 2018 Aug;146(8):823-830

Departamento de Medicina Interna, Clínica Las Condes, Santiago, Chile.

Background: Most cases of Clostridium difficile infection (CDI) respond to a standard course of antibiotics, however recurrent CDI is becoming common and alternative therapeutic strategies are needed. In this scenario, fecal microbiota transplantation (FMT) has been suggested.

Aim: To describe the efficacy and safety of FMT for the treatment of recurrent CDI. Read More

View Article

[Ruptured ascending colonic varices in a patient with alcoholic liver cirrhosis treated using topical skin adhesive:a case study].

Nihon Shokakibyo Gakkai Zasshi 2018 ;115(12):1087-1093

Third Department of Internal Medicine, Nara Medical University.

A 59-year-old man had been admitted to our hospital because of general malaise and abdominal fullness caused by massive ascites. He was diagnosed with alcoholic liver cirrhosis. Following the removal of ascites, he was referred to our department because of hematochezia. Read More

View Article
January 2018

Performance of colorectal cancer screening in the European Union Member States: data from the second European screening report.

Gut 2018 Dec 10. Epub 2018 Dec 10.

SSD Epidemiologia e screening - CPO, University Hospital 'Città della Salute e della Scienza', Turin, Italy.

Objective: To present comparative data about the performance of colorectal cancer (CRC) screening programmes in the European Union Member States (EU MSs).

Design: Cross-sectional study. We analysed key performance indicators-participation rate, positivity rate (PR), detection rate (DR) and positive predictive value for adenomas and CRC-based on the aggregated quantitative data collected for the second EU screening report. Read More

View Article
December 2018
14.660 Impact Factor

Compared Abilities of Endoscopic Techniques to Increase Colon Adenoma Detection Rates: A Network Meta-analysis.

Clin Gastroenterol Hepatol 2018 Dec 6. Epub 2018 Dec 6.

Division of Gastroenterology, University of California San Diego, La Jolla, California; Division of Biomedical Informatics, University of California San Diego, La Jolla, California.

Background And Aims: Adenoma detection rate (ADR) is a quality metric for colorectal cancer screening. We performed a systematic review and network meta-analysis to assess the overall and comparative efficacies of different endoscopic techniques in adenoma detection.

Methods: We performed a systematic review of published articles and abstracts, through March 15, 2018, to identify randomized controlled trials of adults undergoing colonoscopy that compared the efficacy of different devices in detection of adenomas. Read More

View Article
December 2018

Safety and efficacy of hot avulsion as an adjunct to endoscopic mucosal resection (with videos).

Gastrointest Endosc 2018 Dec 5. Epub 2018 Dec 5.

Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University School of Medicine. Electronic address:

Background: Excision of all visible neoplastic tissue is the goal of endoscopic mucosal resection (EMR) of colorectal laterally spreading tumors (LSTs). Flat and fibrotic tissue can resist snaring. Ablation of visible polyps is associated with high recurrence rates. Read More

View Article
December 2018
1 Read

[Knowledge and attitude among general practitioners in Andalusia (Spain) on the identification of subjects at high risk of breast and colorectal cancer].

Semergen 2018 Oct 24. Epub 2018 Oct 24.

Médico de Familia, Unidad de Gestión Clínica Ciudad Jardín, Distrito Sanitario Málaga-Guadalhorce, Málaga, España. Electronic address:

Aims: To assess the knowledge and attitude among general practitioners in Andalusia on the identification of subjects with elevated risk for breast cancer, colorectal cancer, and hereditary cancers, as well as to detect barriers to accessibility to the screening programs.

Methods: A descriptive, cross-sectional study was conducted based on an online survey of 24 questions. Data are shown as frequencies, and association tests were statistically used. Read More

View Article
October 2018

Artificial intelligence and computer-aided diagnosis in colonoscopy: current evidence and future directions.

Lancet Gastroenterol Hepatol 2019 Jan 6;4(1):71-80. Epub 2018 Dec 6.

Wellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London, UK; Division of Surgery & Interventional Science, University College London, London, UK; Gastrointestinal Services, University College London Hospital, London, UK.

Computer-aided diagnosis offers a promising solution to reduce variation in colonoscopy performance. Pooled miss rates for polyps are as high as 22%, and associated interval colorectal cancers after colonoscopy are of concern. Optical biopsy, whereby in-vivo classification of polyps based on enhanced imaging replaces histopathology, has not been incorporated into routine practice because it is limited by interobserver variability and generally only meets accepted standards in expert settings. Read More

View Article
January 2019

The Adult Well-Male Examination.

Am Fam Physician 2018 Dec;98(12):729-737

University of Michigan Medical School, Ypsilanti, MI, USA.

The adult well-male examination should provide evidence-based guidance toward the promotion of optimal health and well-being. The medical history should focus on tobacco and alcohol use, risk of human immunodeficiency virus and other sexually transmitted infections, and diet and exercise habits. The physical examination should include blood pressure screening, and height and weight measurements to calculate body mass index. Read More

View Article
December 2018

Clostridium septicum: A usual suspect? Aortic rupture following right hemicolectomy: A case report.

Int J Surg Case Rep 2018 Nov 22;54:51-54. Epub 2018 Nov 22.

Department of Surgery, Epworth Health, Melbourne Australia; Gastrointestinal Clinical Institute, Epworth HealthCare, Melbourne Australia.

Introduction: There is a known association between Clostridium Septicum, mycotic aneurysm and colon neoplasm.

Case Presentation: We report the case of a 90 year old female admitted with abdominal pain to the general surgery unit. Admission CT scan demonstrated a thick walled caecum and pericaecal inflammation suspicious for a perforated carcinoma. Read More

View Article
November 2018
4 Reads

A case of duodenal hemorrhage due to arteriovenous malformation around a serous cystic neoplasm.

Surg Case Rep 2018 Dec 5;4(1):140. Epub 2018 Dec 5.

Department of Hepato-Biliary-Pancreatic Surgery, Shizuoka Cancer Center, 1007, Shimo-Nagakubo, Sunto-Nagaizumi, Shizuoka, 4118777, Japan.

Background: No reports have so far described arteriovenous malformation (AVM) in the pancreas caused by a tumor. We herein report a case of pancreatoduodenectomy for a patient who developed duodenal hemorrhage due to AVM developed around serous cystic neoplasm (SCN) of the pancreas.

Case Presentation: A 79-year-old man was referred to our hospital because of anemia (Hb 7. Read More

View Article
December 2018
3 Reads

Endoscopy Is Relatively Safe in Patients with Acute Ischemic Stroke and Gastrointestinal Hemorrhage.

Dig Dis Sci 2018 Dec 5. Epub 2018 Dec 5.

Department of Gastroenterology, New York Medical College, Valhalla, NY, 10595, USA.

Background: Gastrointestinal hemorrhage (GIH) is reported to occur in 1-8% of patients admitted with acute ischemic stroke (AIS). AIS is considered to be a relative contraindication to GIE.

Aims: Evaluate the outcomes of gastrointestinal endoscopy (GIE) in patients hospitalized with AIS and GIH. Read More

View Article
December 2018
2 Reads

Usefulness of transabdominal ultrasonography for assessing ulcerative colitis: a prospective, multicenter study.

J Gastroenterol 2018 Dec 5. Epub 2018 Dec 5.

Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7 Kita-ku, Sapporo, 060-8638, Japan.

Background: Transabdominal ultrasonography (US) has been reported to be a useful tool for evaluating ulcerative colitis (UC) although with less well-established data than for Crohn's disease. This prospective multicenter study aimed to establish the usefulness of US compared with colonoscopy (CS) for assessing disease extent and activity of UC.

Methods: Altogether, 173 patients with UC were prospectively enrolled, among whom 156 were eligible for this study. Read More

View Article
December 2018
1 Read

Colonoscopy-related complications in a nationwide immunochemical fecal occult blood test-based colorectal cancer screening program.

Clin Epidemiol 2018 13;10:1649-1655. Epub 2018 Nov 13.

Department of Digestive Diseases K, Bispebjerg Hospital, Copenhagen, Denmark.

Background: The Danish national screening program for colorectal cancer (CRC) consists of an immunochemical fecal occult blood test (iFOBT) followed by colonoscopy. The Danish Colorectal Cancer Screening Database (DCCSD) records data on the incidence of hospital-registered complications after colonoscopy. However, the validity of these data is unknown, and the incidence of complications is potentially underreported. Read More

View Article
November 2018

Risk of Post-polypectomy Bleeding With Uninterrupted Clopidogrel Therapy in an Industry-independent, Double-blind, Randomized Trial.

Gastroenterology 2018 Oct 25. Epub 2018 Oct 25.

Department of Medicine & Therapeutics, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China (SAR); State Key Laboratory of Digestive Disease, LKS Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China (SAR).

Background & Aims: Guidelines recommend withholding clopidogrel 7 days before polypectomy to reduce bleeding risk, but these were written based on limited evidence. We investigated whether uninterrupted clopidogrel therapy increases the risk of delayed post-polypectomy bleeding in patients undergoing colonoscopy.

Methods: We identified patients receiving clopidogrel for cardiovascular disease undergoing elective colonoscopies in Hong Kong, from 28 February 2012 through 11 April 2018. Read More

View Article
October 2018
2 Reads

Invitation to Screening Colonoscopy in the Population at Familial Risk for Colorectal Cancer.

Dtsch Arztebl Int 2018 Oct;115(43):715-722

Institute for General Medicine, Faculty of Medicine, University of Halle-Wittenberg, Halle; Institute for Health and Nursing Sciences, Faculty of Medicine, University of Halle-Wittenberg, Halle; Director Emeritus, Department of Medicine C, Ludwigshafen Hospital, c/o LebensBlicke Foundation, Ludwigshafen; Department of Internal Medicine I, Ulm University Hospital, Ulm; Department of Medicine I, Braunschweig Municipal Hospital, Braunschweig; Department of Gastroenterology, Celle General Hospital, Celle; Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen; Faculty of Human and Health Sciences, University of Bremen; Institute for Medical Epidemiology, Biometrics, and Information Science, Faculty of Medicine, University of Halle-Wittenberg, Halle; Nursing Research Unit, Halle University Hospital, Halle: Madeleine Ritter-Herschbach, MScN, RN; Department for Health, University of Bath, Claverton Down, Bath, UK.

Background: Screening colonoscopy can lower the incidence of colorectal cancer (CRC), yet participation rates are low even in groups at high risk. The goal of this study was to double the rate of participation in screening colonoscopy among persons at familial risk and then to determine the frequency of neoplasia in this risk group.

Methods: In a nationwide, cluster-randomized, multicenter study, first-degree relatives (FDR) of patients with CRC across Germany received written informational materials concerning the familial risk of CRC, along with an invitation to undergo colonoscopy. Read More

View Article
October 2018
1 Read

Image-Enhanced Endoscopy in Lower Gastrointestinal Diseases: Present and Future.

Clin Endosc 2018 Nov 30;51(6):534-540. Epub 2018 Nov 30.

Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

From dye-assisted conventional chromoendoscopy to novel virtual chromoendoscopy, image-enhanced endoscopy (IEE) is continuously evolving to meet clinical needs and improve the quality of colonoscopy. Dye-assisted chromoendoscopy using indigo carmine or crystal violet, although slightly old-fashioned, is still useful to emphasize the pit patterns of the colonic mucosa and predict the histological structures of relevant lesions. Equipment-based virtual chromoendoscopy has the advantage of being relatively easy to use. Read More

View Article
November 2018
3 Reads

Screening initiation with FIT or colonoscopy: Post-hoc analysis of a pragmatic, randomized trial.

Prev Med 2018 Dec 1;118:332-335. Epub 2018 Dec 1.

Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States of America; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States of America; Harold C. Simmons Comprehensive Cancer Center, Dallas, TX, United States of America; Department of Medicine, UC San Diego Medical Center, San Diego, CA, United States of America; Veterans Affairs San Diego Healthcare System, San Diego, CA, United States of America.

Screening with FIT or colonoscopy can reduce CRC mortality. In our pragmatic, randomized trial of screening outreach over three years, patients annually received mailed FITs or colonoscopy invitations. We examined screening initiation after each mailing and crossover from the invited to other modality. Read More

View Article
December 2018
1 Read

[Association of serum inflammatory cytokines and Resolvin D1 concentration with pathological stage of colon cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1285-1290

Department of General Surgery, Fudan University Affliated Zhongshan Hospital, Shanghai 200032, China. Email:

Objective: To investigate the levels of serum inflammatory cytokines and Resolvin D1 (RvD1) and their association with pathological staging of colon cancer.

Methods: Clinical data of 50 colon cancer patients (colon cancer group) admitted to the General Surgery Department of Zhongshan Hospital of Fudan University from January to December 2016 and 5 ml of whole blood specimen were collected at admission. During the same period, 50 healthy volunteers were enrolled (healthy volunteer group). Read More

View Article
November 2018
1 Read

A unique case of ileal Dieulafoy's lesion diagnosed and treated by cap-assisted water immersion colonoscopy.

VideoGIE 2018 Dec 4;3(12):401-402. Epub 2018 Oct 4.

Division of Gastroenterology, Sacramento Veterans Affairs Medical Center, Veterans Affairs Northern California Health Care System, University of California, Davis School of Medicine, Sacramento, California, USA.

View Article
December 2018

EndCancer: development and pilot testing of multimedia recruitment for a text message campaign to increase cancer screening.

Mhealth 2018 31;4:50. Epub 2018 Oct 31.

Department of Community and Behavioral Health, Colorado School of Public Health, Aurora, CO 80045, USA.

Background: Colorectal cancer (CRC) is the second leading cause of cancer mortality in the US but is preventable with timely colonoscopy screening. Although CRC incidence and mortality have been decreasing and screening rates increasing, southeastern Coloradans in particular remain in great need of CRC screening. Media outreach campaigns have previously proven successful in this region, and local clinical partners expressed interest in text messaging and social media community outreach. Read More

View Article
October 2018

Low-literacy Level Instructions and Reminder Calls Improve Patient Handling of Fecal Immunochemical Test Samples.

Clin Gastroenterol Hepatol 2018 Nov 29. Epub 2018 Nov 29.

Division of Gastroenterology, University of California, San Francisco, San Francisco, CA, United States; Center for Vulnerable Populations, University of California, San Francisco, San Francisco, CA, United States. Electronic address:

Background & Aims: The fecal immunochemical test (FIT) is an alternative to colonoscopy and can increase overall screening for colorectal cancer (CRC). However, little is known about the frequency of and reasons for mishandled FIT samples.

Methods: We performed a prospective study, nested within a randomized controlled trial of patients, recruited from December 2015 through August 2017, who were not up to date with colorectal cancer screening (50-75 years old). Read More

View Article
November 2018
1 Read

Patients Prescribed Direct-acting Oral Anticoagulants Have Low Risk of Post-Polypectomy Complications.

Clin Gastroenterol Hepatol 2018 Nov 29. Epub 2018 Nov 29.

Division of Gastroenterology, San Francisco Veterans Affairs Medical Center, University of California San Francisco, San Francisco, CA, United States.

Background & Aims: Use of direct-acting oral anticoagulants (DOACs) is increasing, but little is known about the associated risks in patients undergoing colonoscopy with polypectomy. We aimed to determine the risk of post-polypectomy complications in patients prescribed DOACs.

Methods: We performed a retrospective analysis using the Clinformatics Data Mart Database (a de-identified administrative database from a large national insurance provider) to identify adults who underwent colonoscopy with polypectomy or endoscopic mucosal resection (EMR) from January 1, 2011, through December 31, 2015. Read More

View Article
November 2018
6 Reads

Appendiceal Mucocele - Unexpected Finding in Colonoscopy.

Clin Gastroenterol Hepatol 2018 Nov 28. Epub 2018 Nov 28.

Hospital Garcia de Orta, Gastroenterology department, Almada, Portugal; CUF Almada Clínica, Gastroenterology department, Almada, Portugal.

View Article
November 2018
2 Reads

Clinical Features and Outcomes of Patients With Acute Mesenteric Ischemia and Concomitant Colon Ischemia: A Retrospective Cohort Study.

J Surg Res 2019 Jan 31;233:231-239. Epub 2018 Aug 31.

Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.

Background: Early identification of patients with acute mesenteric ischemia (AMI) involving the large bowel may play a decisive role in improving the prognosis of AMI. This study aims to compare the outcomes between patients with isolated AMI and AMI patients with colon involvement (CI) and to identify the predictors of worse outcomes. The different surgical modalities for AMI patients with CI were also evaluated. Read More

View Article
January 2019
1 Read

A Case of Asymptomatic Syphilitic Proctitis.

Sex Transm Dis 2018 Dec 3. Epub 2018 Dec 3.

Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles.

The incidence of syphilis is increasing. Syphilitic proctitis involving the rectal mucosa often presents with pain on defecation, rectal bleeding, or ulceration. We present a case of asymptomatic syphilitic proctitis diagnosed upon a routine screening colonoscopy. Read More

View Article
December 2018
2 Reads

CORR Insights®: Proximal Femur Hounsfield Units on CT Colonoscopy Correlate With Dual-energy X-ray Absorptiometry.

Authors:
Wayne Cheng

Clin Orthop Relat Res 2018 Nov 27. Epub 2018 Nov 27.

W. Cheng, Professor, Department of Orthopedic Surgery, VA Loma Linda Health Care System, San Bernardino, CA, USA.

View Article
November 2018
1 Read

A National Bowel Cancer Screening Programme using FIT: Achievements and challenges.

Cancer Prev Res (Phila) 2018 Dec 4. Epub 2018 Dec 4.

BowelScreen, National Screening Service.

Colorectal Cancer (CRC) accounts for 11% of all cancer deaths in Ireland. With the aim of diagnosing these cancers at an earlier stage, and detecting pre-malignant lesions, the National Screening Service offered a Faecal Immunochemical Test (FIT) to all individuals aged 60-69. All individuals in the age range were contacted by post and invited to participate in the programme. Read More

View Article
December 2018

Combined Gastric and Colorectal Cancer Screening-A New Strategy.

Int J Mol Sci 2018 Dec 3;19(12). Epub 2018 Dec 3.

Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.

Background: Our aim was to evaluate the feasibility of a serological assessment of gastric cancer risk in patients undergoing colonoscopy in countries with low-to-moderate incidence rates.

Methods: Serum samples were prospectively collected from 453 patients (>50 years old) undergoing colonoscopies. Of these, 279 (61. Read More

View Article
December 2018
2 Reads

Colonic metastasis from infiltrating ductal breast carcinoma in a male patient: A case report.

Int J Surg Case Rep 2018 Nov 16;54:34-38. Epub 2018 Nov 16.

Department of Surgery, Palmetto Healthcare System, University of South Carolina Medical School, 2 Medical Park Road, Columbia, SC 29203, United States. Electronic address:

Introduction: A colonic metastasis from infiltrating breast ductal carcinoma is a rare phenomenon in the literature, especially in a male.

Presentation Of Case: We present a rare case of a 55-year-old male with a past medical history of breast cancer who presented with signs and symptoms of appendicitis. A computed tomography (CT) scan revealed acute appendicitis in addition to a 2. Read More

View Article
November 2018
6 Reads