39,667 results match your criteria Colonoscopy


Label-Free Multiphoton Endomicroscopy for Minimally Invasive In Vivo Imaging.

Adv Sci (Weinh) 2019 Apr 25;6(8):1801735. Epub 2019 Feb 25.

Institute of Medical Biotechnology Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) Paul-Gordan-Str. 3 91052 Erlangen Germany.

Multiphoton microscopy of cellular autofluorescence and second harmonic generation from collagen facilitates imaging of living cells and tissues without the need for additional fluorescent labels. Here, a compact multiphoton endomicroscope for label-free in vivo imaging in small animals via side-viewing needle objectives is presented. Minimal invasive imaging at cellular resolution is performed in colonoscopy of mice without surgical measures and without fluorescent dyes as a contrast agent. Read More

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http://dx.doi.org/10.1002/advs.201801735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468963PMC

Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy.

Nat Biomed Eng 2018 Oct 10;2(10):741-748. Epub 2018 Oct 10.

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.

The detection and removal of precancerous polyps via colonoscopy is the gold standard for the prevention of colon cancer. However, the detection rate of adenomatous polyps can vary significantly among endoscopists. Here, we show that a machine-learning algorithm can detect polyps in clinical colonoscopies, in real time and with high sensitivity and specificity. Read More

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http://dx.doi.org/10.1038/s41551-018-0301-3DOI Listing
October 2018

The Mexican consensus on the diagnosis and treatment of diverticular disease of the colon.

Rev Gastroenterol Mex 2019 Apr 20. Epub 2019 Apr 20.

División de Cirugía, Instituto Nacional de Ciencias Médicas y Nutrición «Salvador Zubirán», Ciudad de México, México.

Since the publication of the 2008 guidelines on the diagnosis and treatment of diverticular disease of the colon by the Asociación Mexicana de Gastroenterología, significant advances have been made in the knowledge of that disease. A systematic review of articles published in the medical literature from January 2008 to July 2018 was carried out to revise and update the 2008 guidelines and provide new evidence-based recommendations. All high-quality articles in Spanish and English published within that time frame were included. Read More

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http://dx.doi.org/10.1016/j.rgmx.2019.01.002DOI Listing

Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study.

Korean J Gastroenterol 2019 Mar;73(3):152-158

, Wonju; Department of Biostatistics, Yonsei University.

Background/aims: Despite the many reports of colonoscopy complications worldwide, few studies have been performed at the population level in Korea. In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group.

Methods: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2019.73
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http://dx.doi.org/10.4166/kjg.2019.73.3.152DOI Listing
March 2019
1 Read

Herpes Simplex Virus Proctitis Masquerading as Rectal Cancer.

Diseases 2019 Apr 21;7(2). Epub 2019 Apr 21.

Department of Pathology and Laboratory Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.

Herpes simplex virus (HSV) is the leading cause of proctitis in HIV-infected individuals. However, no cases of rectal masses secondary to HSV infection have been reported to date. Herein, we present the case of a 45-year-old man with HIV infection who developed rectal pain and bleeding, along with dysuria and voiding difficulty. Read More

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http://dx.doi.org/10.3390/diseases7020036DOI Listing

Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis.

J Proteomics 2019 Apr 19. Epub 2019 Apr 19.

Bioprocess Engineering, Otto von Guericke University, Universitätsplatz 2, Magdeburg 39106, Germany. Electronic address:

Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory bowel diseases (IBD) of the gastrointestinal tract. This study used non-invasive LC-MS/MS to find disease specific microbial and human proteins which might be used later for an easier diagnosis. Therefore, 17 healthy controls, 11 CD patients and 14 UC patients but also 13 Irritable Bowel Disease (IBS) patients, 8 Colon Adenoma (CA) patients, and 8 Gastric Carcinoma (GCA) patients were investigated. Read More

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http://dx.doi.org/10.1016/j.jprot.2019.04.009DOI Listing

Efficacy of Fecal Microbiota Transplantation for Clostridium difficile Infection in Children.

Clin Gastroenterol Hepatol 2019 Apr 19. Epub 2019 Apr 19.

Boston Children's Hospital, Boston, MA. Electronic address:

Background & Aims: Fecal microbiota transplantation (FMT) is commonly used to treat Clostridium difficile infection (CDI). CDI is an increasing cause of diarrheal illness in pediatric patients, but the effects of FMT have not been well studied in children. We performed a multi-center retrospective cohort study of pediatric and young adult patients to evaluate the efficacy, safety, and factors associated with a successful FMT for the treatment of CDI. Read More

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http://dx.doi.org/10.1016/j.cgh.2019.04.037DOI Listing

Detection rates of dysplasia in patients with inflammatory bowel disease using dye-based chromoendoscopy compared with standard- and high-definition white-light colonoscopy: a systematic review and meta-analysis.

Gastrointest Endosc 2019 Apr 19. Epub 2019 Apr 19.

Division of Gastroenterology, Beth Israel Deaconess Medical Center.

Background: Patients with ulcerative colitis have an increased risk of colorectal cancer. We sought to assess the comparative efficacy of standard white-light endoscopy (SDWLE) or high-definition white-light endoscopy (HDWLE) versus dye-based chromoendoscopy through a meta-analysis and rating the quality of evidence using the GRADE system.

Methods: A systematic review of the literature in PubMed, EMBASE, and Web of Sciences was performed through April 2018. Read More

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http://dx.doi.org/10.1016/j.gie.2019.04.219DOI Listing

The Effect of Allogenic Versus Autologous Fecal Microbiota Transfer on Symptoms, Visceral Perception and Fecal and Mucosal Microbiota in Irritable Bowel Syndrome: A Randomized Controlled Study.

Clin Transl Gastroenterol 2019 Apr 15. Epub 2019 Apr 15.

Nutrition-Gut-Brain Interactions Research Centre, Faculty of Health and Medicine, School of Medical Sciences, Örebro University, Örebro, Sweden.

Objectives: Fecal microbiota transfer (FMT) is suggested as a potential treatment for patients with irritable bowel syndrome (IBS). We aimed to study the effect of allogenic and autologous FMT on IBS symptoms, visceral sensitivity, and compositional changes in fecal and mucosa-adherent microbiota.

Methods: Seventeen patients with IBS were randomized either to receive fecal material from a healthy donor (allogenic) or to receive their own fecal material (autologous). Read More

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http://dx.doi.org/10.14309/ctg.0000000000000034DOI Listing

Cost savings following faecal microbiota transplantation for recurrent infection.

Therap Adv Gastroenterol 2019 10;12:1756284819843002. Epub 2019 Apr 10.

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200 Aarhus N, Denmark.

Background: Recurrent infection (rCDI) is becoming increasingly common. Faecal microbiota transplantation (FMT) is effective for rCDI, but the costs of an FMT and hospital cost savings related to FMT are unknown. The aim of this study was to calculate the cost of an FMT and the total hospital costs before and after FMT. Read More

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http://dx.doi.org/10.1177/1756284819843002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460887PMC

Cecal Mucosal Myxoma: The First Report of a New Type of Mesenchymal Colon Polyp.

Int J Surg Pathol 2019 Apr 22:1066896919843625. Epub 2019 Apr 22.

1 University of Rochester, Rochester, NY, USA.

Myxomas are benign mesenchymal neoplasms of unknown etiology that most commonly occur in the cardiac atrium; however, other reported sites include the skin, joints, skeletal muscles, maxillofacial bones, and sinonasal tract. Myxomas involving the gastrointestinal (GI) tract are rare and are limited to a few published case reports. We are presenting, to our knowledge, the first case report of a mucosal myxoma in the colon presenting as a colonic polyp. Read More

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http://dx.doi.org/10.1177/1066896919843625DOI Listing

Comparative evaluation of novel screening strategies for colorectal cancer screening in China (TARGET-C): a study protocol for a multicentre randomised controlled trial.

BMJ Open 2019 Apr 20;9(4):e025935. Epub 2019 Apr 20.

Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Introduction: Screening for colorectal cancer (CRC) is effective in reducing the disease burden. However, high-level evidence from randomised controlled trials on the effectiveness of CRC screening modalities is still lacking. We will conduct a large-scale multicentre randomised controlled trial in China to evaluate the effectiveness and cost-effectiveness of different CRC screening strategies. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025935DOI Listing

Response.

Gastrointest Endosc 2019 05;89(5):1071-1073

Department of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1016/j.gie.2019.01.015DOI Listing

Total underwater colonoscopy: still murky.

Gastrointest Endosc 2019 05;89(5):1071

Division of Gastroenterology, Sacramento Veterans Affairs Medical Center, University of California Davis Medical Center, Sacramento, California, USA.

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http://dx.doi.org/10.1016/j.gie.2018.12.002DOI Listing

Abdominal Lymphoma Presenting as Terminal Ileitis: A Case Report.

J Emerg Med 2019 Apr 16. Epub 2019 Apr 16.

Department of Emergency Medicine, Cincinnati Children's Hospital and Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Background: Most pediatric patients with lymphoma do not have classic symptoms of fever, night sweats, and weight loss. Lymphoma can present as vague symptoms and may mimic common pediatric abdominal emergencies. In this case report, we present a child who presented with abdominal pain and who was initially misdiagnosed as having a surgical emergency. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07364679193013
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http://dx.doi.org/10.1016/j.jemermed.2019.03.004DOI Listing
April 2019
2 Reads

Time to Follow-up After Colorectal Cancer Screening by Health Insurance Type.

Am J Prev Med 2019 May;56(5):e143-e152

Office of Disease Prevention, NIH, Bethesda, Maryland.

Introduction: The purpose of this study was to test the hypothesis that patients with Medicaid insurance or Medicaid-like coverage would have longer times to follow-up and be less likely to complete colonoscopy compared with patients with commercial insurance within the same healthcare systems.

Methods: A total of 35,009 patients aged 50-64years with a positive fecal immunochemical test were evaluated in Northern and Southern California Kaiser Permanente systems and in a North Texas safety-net system between 2011 and 2012. Kaplan-Meier estimation was used between 2016 and 2017 to calculate the probability of having follow-up colonoscopy by coverage type. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07493797193003
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http://dx.doi.org/10.1016/j.amepre.2019.01.005DOI Listing
May 2019
1 Read

Submucosal mucoid as a late complication after appendectomy-A case report.

Int J Surg Case Rep 2019 Apr 5;58:37-40. Epub 2019 Apr 5.

Radiological Department, Klatovy Hospital, Plzeňská 929, 339 01, Klatovy II, Czech Republic.

Introduction: Shortly after an operation infection, intraabdominal abscess, seroma, haemorrhage or development of paralytic ileus may occur. Postoperative adhesions, nonspecific abdominal pain without signs of obstruction, incisional hernia and appendicitis or mucocele in appendiceal stump present common late complications. We present a unique case of a late complication after appendectomy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612193017
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http://dx.doi.org/10.1016/j.ijscr.2019.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475718PMC
April 2019
1 Read

Intestinal Perforation in ACTH-Dependent Cushing's Syndrome.

Biomed Res Int 2019 13;2019:9721781. Epub 2019 Mar 13.

Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred more frequently in patients with ectopic ACTH syndrome and in those with a greater than 10-fold elevation of 24-hour urinary free cortisol level. Read More

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http://dx.doi.org/10.1155/2019/9721781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436364PMC

A case of screening colonoscopy using linked-color imaging to detect ulcerative colitis-associated colorectal cancer.

Dig Liver Dis 2019 Apr 15. Epub 2019 Apr 15.

Digestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.

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http://dx.doi.org/10.1016/j.dld.2019.03.010DOI Listing

Narrow-band Imaging for Detection of Neoplasia at Colonoscopy: a Meta-analysis of Data From Individual Patients in Randomized Controlled Trials.

Gastroenterology 2019 Apr 15. Epub 2019 Apr 15.

Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, and Oxford NIHR Biomedical Research Centre, Oxford OX3 9DU, UK. Electronic address:

Background & Aims: Adenoma detection rate (ADR) is an important quality assurance measure for colonoscopy. Some studies suggest that narrow band imaging (NBI) may be more effective at detection of adenomas than white-light endoscopy (WLE) when bowel preparation is optimal. We conducted a meta-analysis of data from individual patients in randomized controlled trials that compared the efficacy of NBI to WLE in detection of adenomas. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193570
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http://dx.doi.org/10.1053/j.gastro.2019.04.014DOI Listing
April 2019
5 Reads

Recommended Cancer Screening in Accountable Care Organizations: Trends in Colonoscopy and Mammography in the Medicare Shared Savings Program.

J Oncol Pract 2019 Apr 18:JOP1800352. Epub 2019 Apr 18.

1 Brigham and Women's Hospital, Boston, MA.

Purpose: Accountable care organizations (ACOs) are a delivery and payment model designed to encourage integrated, high-value care. We designed a study to test the association between ACOs and two recommended cancer screening tests, colonoscopy for colorectal cancer and mammography for breast cancer.

Methods: Using the random 20% sample of Medicare claims, beneficiaries were attributed to ACO or non-ACO cohorts on the basis of providers' enrollment in the Medicare Shared Savings Program. Read More

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http://dx.doi.org/10.1200/JOP.18.00352DOI Listing
April 2019
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Intraoperative colonoscopy in laparoscopic colorectal surgery: A review of recent publications.

Asian J Endosc Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, The University Hong Kong-Shenzhen Hospital, Shenzhen, China.

Introduction: Laparoscopic colorectal resection is becoming the gold standard for treating colorectal cancers because it offers superior short-term and comparable long-time outcomes compared to open surgery. Intraoperative colonoscopy (IOC) is increasingly performed for tumor localization and mucosal assessment. The aim of this report was to review the safety and efficacy of IOC in laparoscopic colorectal surgery. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ases.12704
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http://dx.doi.org/10.1111/ases.12704DOI Listing
April 2019
3 Reads

A provider feedback intervention to increase uptake of colorectal cancer screening in a Swiss academic general practice.

BMJ Open Qual 2019 3;8(1):e000452. Epub 2019 Mar 3.

Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

Colorectal cancer (CRC) cancer screening uptake is low in our diverse, outpatient teaching clinic. A state-level public screening programme was recently launched that provides faecal immunochemical tests or screening colonoscopy to all citizens aged 50-69 years via mailed invitations, with the possibility of earlier, opportunistic inclusion. Mailed outreach is expected to be rolled out over the next 5 years. Read More

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http://dx.doi.org/10.1136/bmjoq-2018-000452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440588PMC

The efficacy of fecal microbiota transplantation for patients with chronic pouchitis: A case series.

Clin Case Rep 2019 Apr 12;7(4):782-788. Epub 2019 Mar 12.

Department of Medicine Shiga University of Medical Science Otsu Japan.

Pouchitis is one of the most common complications that develop after restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Single fecal microbiota transplantation (FMT) by colonoscopy was performed safely on three patients with pouchitis. However, the efficacy of FMT on pouchitis was limited. Read More

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http://dx.doi.org/10.1002/ccr3.2096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452488PMC

Usefulness of Ustekinumab for Treating a Case of Myelodysplastic Syndrome-Associated Inflammatory Bowel Disease.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.

Autoimmune diseases including inflammatory bowel disease (IBD) occur in association with myelodysplastic syndrome (MDS). MDS-associated IBD frequently demonstrates a complicated course. We herein report the first case with MDS-associated IBD that was successfully treated with ustekinumab (UST), an anti-interleukin (IL) 12/23p40 monoclonal antibody. Read More

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http://dx.doi.org/10.2169/internalmedicine.2495-18DOI Listing
April 2019
1 Read
0.967 Impact Factor

The Usefulness of Video Capsule Endoscopy in Evaluating Gastrointestinal Manifestations of Immunoglobulin A Vasculitis.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Second Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Japan.

Objective Immunoglobulin (Ig) A vasculitis (IgAV) is a systemic vasculitis characterized by purpura and gastrointestinal involvement showing abdominal pain that usually occurs after the emergence of purpura. Criteria for evaluating gastrointestinal manifestations of IgAV are unavailable at present, so we conducted a study to investigate the usefulness of video capsule endoscopy (VCE) for detecting gastrointestinal manifestations of IgAV. Methods The clinical data of 10 patients who underwent VCE for IgAV at our hospital from 2012 to 2017 were collected. Read More

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http://dx.doi.org/10.2169/internalmedicine.2097-18DOI Listing
April 2019
1 Read

Concerns regarding the recommendations of the British Society of Gastroenterology's lower GI bleeding guidelines.

Gut 2019 Apr 17. Epub 2019 Apr 17.

Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

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http://dx.doi.org/10.1136/gutjnl-2019-318582DOI Listing
April 2019
1 Read

A case of ectopic pancreas in the ileum presenting as obscure gastrointestinal bleeding and abdominal pain.

BMC Gastroenterol 2019 Apr 17;19(1):57. Epub 2019 Apr 17.

Clinic of Gastroenterology, Nephrourology and Surgery, Vilnius University, Santariskiu street 2, 08406, Vilnius, LT, Lithuania.

Background: Ectopic pancreas is an infrequent submucosal tumor in the gastrointestinal tract defined as a pancreatic tissue lacking vascular or anatomic continuity with the main body of the pancreas. Ectopic pancreas in the ileum is a rare and often an incidental finding. We report a case of ectopic pancreas in the ileum causing obscure gastrointestinal bleeding and episodes of abdominal pain. Read More

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http://dx.doi.org/10.1186/s12876-019-0971-7DOI Listing
April 2019
1 Read

En bloc resection for 10-20 mm polyps to reduce post-colonoscopy cancer and surveillance.

Clin Gastroenterol Hepatol 2019 Apr 14. Epub 2019 Apr 14.

Endoscopy Unit, Humanitas University, Rozzano, Milano, Italy.

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http://dx.doi.org/10.1016/j.cgh.2019.04.022DOI Listing
April 2019
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Association of Adenoma and Proximal Sessile Serrated Polyp Detection Rates With Endoscopist Characteristics.

JAMA Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio.

Importance: Research demonstrates adenoma detection rate (ADR) and proximal sessile serrated polyp detection rate (pSSPDR) are associated with endoscopist characteristics including sex, specialty, and years in practice. However, many studies have not adjusted for other risk factors associated with colonic neoplasia.

Objective: To assess the association between endoscopist characteristics and polyp detection after adjusting the factors included in previous studies as well as other factors. Read More

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2019.0564DOI Listing
April 2019
1 Read

Screening Colonoscopy Should Be Available to All.

JAMA Surg 2019 Apr 17. Epub 2019 Apr 17.

Department of Surgery, Baylor University Medical Center, Dallas, Texas.

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2019.0565DOI Listing
April 2019
1 Read

Impact of Automated Time-released Reminders on Patient Preparedness for Colonoscopy.

J Clin Gastroenterol 2019 Apr 15. Epub 2019 Apr 15.

Division of Gastroenterology, Hepatology and Endoscopy.

Goals: To evaluate the effect of an automated time-released colonoscopy reminder program on preparation quality and the rates of canceled procedures.

Background: Patients missing colonoscopy appointments or arriving with inadequate bowel preparations result in delays in care and increase in health care costs.

Study: We initiated a quality improvement program which included switching to a split-dose preparation and delivering preparation instructions and appointment reminders via text messages and emails sent with an automated time-released HIPAA-compliant software platform. Read More

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http://dx.doi.org/10.1097/MCG.0000000000001211DOI Listing
April 2019
1 Read

Clinical usefulness of magnifying colonoscopy for the diagnosis of ulcerative colitis-associated neoplasia.

Dig Endosc 2019 Apr;31 Suppl 1:36-42

Division of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.

Background And Aim: The aim of this investigation was to evaluate the efficacy of Japanese magnifying colonoscopic classifications for ulcerative colitis-associated neoplasia (UCAN).

Methods: We reviewed the colonoscopy records from 2011 to 2018 at our institutions and identified cases of endoscopically or surgically resected UCAN observed by magnifying narrow-band imaging (NBI) endoscopy and magnifying chromoendoscopy. Association between magnifying endoscopic classification and histopathological findings was investigated retrospectively. Read More

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http://dx.doi.org/10.1111/den.13382DOI Listing
April 2019
3 Reads

Recurrence of adenoma after curative endoscopic submucosal dissection for a rectal intramucosal adenocarcinoma in adenoma.

Endosc Int Open 2019 Apr 12;7(4):E621-E624. Epub 2019 Apr 12.

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

 A 71-year-old female underwent endoscopic submucosal dissection (ESD) for a subcircumferential lateral-spreading rectal tumor. Pathological examination showed an intramucosal adenocarcinoma in villous adenoma (size: 155 × 140 mm), which had been curatively resected with negative margins. However, follow-up colonoscopy revealed a tumor at the ulcer scar site, which soon grew into a circumferential lesion. Read More

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http://dx.doi.org/10.1055/a-0867-9737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461547PMC
April 2019
1 Read

The impact of personalised risk information compared to a positive/negative result on informed choice and intention to undergo colonoscopy following colorectal Cancer screening in Scotland (PERICCS) - a randomised controlled trial: study protocol.

BMC Public Health 2019 Apr 16;19(1):411. Epub 2019 Apr 16.

Psychology, University of Stirling, Stirling, FK9 4LA, UK.

Background: In Scotland a new, easier to complete bowel screening test, the Faecal Immunochemical Test (FIT), has been introduced. This test gives more accurate information about an individual's risk of having colorectal cancer (CRC), based on their age and gender, and could lead to fewer missed cancers compared to the current screening test. However, there is no evidence of the effect on colonoscopy uptake of providing individuals with personalised risk information following a positive FIT test. Read More

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http://dx.doi.org/10.1186/s12889-019-6734-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469206PMC
April 2019
1 Read

Bridging Warfarin Before Colonoscopy in Patients with Atrial Fibrillation.

Am Fam Physician 2019 Apr;99(8):519-524

University of Colorado Health Sciences Library, Denver, CO, USA.

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April 2019
2 Reads

Implicit domain adaptation with conditional generative adversarial networks for depth prediction in endoscopy.

Int J Comput Assist Radiol Surg 2019 Apr 15. Epub 2019 Apr 15.

Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, London, UK.

Purpose: Colorectal cancer is the third most common cancer worldwide, and early therapeutic treatment of precancerous tissue during colonoscopy is crucial for better prognosis and can be curative. Navigation within the colon and comprehensive inspection of the endoluminal tissue are key to successful colonoscopy but can vary with the skill and experience of the endoscopist. Computer-assisted interventions in colonoscopy can provide better support tools for mapping the colon to ensure complete examination and for automatically detecting abnormal tissue regions. Read More

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http://dx.doi.org/10.1007/s11548-019-01962-wDOI Listing

Increased Healthcare Utilization by Patients With Inflammatory Bowel Disease Covered by Medicaid at a Tertiary Care Center.

Inflamm Bowel Dis 2019 Apr 16. Epub 2019 Apr 16.

Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, New York, USA.

Background: Low socioeconomic status has been linked with numerous poor health outcomes, but data are limited regarding the impact of insurance status on inflammatory bowel disease (IBD) outcomes. We aimed to characterize utilization of healthcare resources by IBD patients based on health insurance status, using Medicaid enrollment as a proxy for low socioeconomic status.

Methods: We retrospectively identified adult patients with IBD engaged in a colorectal cancer surveillance colonoscopy program from July 2007 to June 2017. Read More

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http://dx.doi.org/10.1093/ibd/izz060DOI Listing
April 2019
1 Read

Pancytopenia as a Consequence of Sepsis and Intravenous Antibiotic Drug Toxicity.

Cureus 2019 Feb 1;11(2):e3994. Epub 2019 Feb 1.

Internal Medicine, Ocala Regional Medical Center/ University of Central Florida College of Medicine, Ocala, USA.

This case involves a 62-year-old male with a prior history of epidural abscess and L1-L2 osteodiscitis who was admitted because of low back pain. The patient was previously treated for methicillin-susceptible Staphylococcus aureus (MSSA) discitis in the L1/L2 vertebral region with intravenous (IV) nafcillin through a peripherally inserted central catheter (PICC). However, he returned after four months with recurrent low back pain along with chills and fever. Read More

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https://www.cureus.com/articles/17399-pancytopenia-as-a-cons
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http://dx.doi.org/10.7759/cureus.3994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443538PMC
February 2019
2 Reads

Colitis cystica profunda of the rectum with adenomatous dysplastic features: Radiologic-pathologic correlation.

Radiol Case Rep 2019 Jun 3;14(6):740-745. Epub 2019 Apr 3.

Radiology Department, Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso 86100, Italy.

Colitis cystica profunda is a rare nonneoplastic condition characterized by the presence of mucus-containing cysts in the submucosa of the right colon and rectum. The etiology is unclear, with a few cases reported in the literature. The presenting symptoms and signs may mimic colorectal adenocarcinoma. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447733PMC
June 2019
2 Reads

Colonoscopy and colorectal cancer rates among octogenarians and nonagenarians: nationwide study of US veterans.

Clin Interv Aging 2019 26;14:609-614. Epub 2019 Mar 26.

Department of Gastroenterology, VA Stratton Medical Center, Albany, NY 12208, USA.

Background: According to Surveillance, Epidemiology and End Results (SEER) database, colorectal cancer (CRC) is the fourth most common type of cancer and second highest in cancer-related death after lung cancer. The SEER database is geographically limited, currently present in only 10-12 states. Though this gives a good approximation about the overall direction of CRC incidence and prevalence, we need more nationwide data to compare numbers. Read More

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http://dx.doi.org/10.2147/CIA.S192497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440444PMC

Validation of US evaluation of ulcerative colitis activity.

Ultrasound Med Biol 2019 Apr 12. Epub 2019 Apr 12.

Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Kita-ku, Sapporo, Japan.

This study was aimed at validating the inter-rater grading agreement for assessing disease activity in patients with established ulcerative colitis (UC) using transabdominal ultrasonography (US) versus colonoscopy (CS). Fifty-seven patients underwent US and CS at four facilities. UC disease activity was assessed using the original US grading system and CS Matts classification. Read More

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http://dx.doi.org/10.1016/j.ultrasmedbio.2019.02.018DOI Listing
April 2019
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Effect of video monitor size on polyp detection: a prospective, randomized, controlled trial.

Gastrointest Endosc 2019 Apr 12. Epub 2019 Apr 12.

Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Background And Aims: The adenoma detection rate (ADR) is the most important quality metric for colonoscopy. Numerous factors are known to influence ADR. However, no data on the effect of monitor size on ADR exist. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165107193158
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http://dx.doi.org/10.1016/j.gie.2019.03.1172DOI Listing
April 2019
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Modifiable Factors Associated with Quality of Bowel Preparation Among Hospitalized Patients Undergoing Colonoscopy.

J Hosp Med 2019 Apr 8;14:E1-E6. Epub 2019 Apr 8.

Center for Value-Based Care Research, Medicine Institute, Cleveland Clinic, Cleveland, Ohio.

Introduction: Inadequate bowel preparation (IBP) is a common problem in hospitalized patients; however, little is known about how to prevent IBP. In a large, multihospital system, we evaluated the association between modifiable factors and IBP rate.

Methods: We reviewed data from adult (≥18 years) inpatients undergoing colonoscopy between January 2011 and June 2017. Read More

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https://www.journalofhospitalmedicine.com/jhospmed/article/1
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http://dx.doi.org/10.12788/jhm.3173DOI Listing
April 2019
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Factors predicting the colorectal adenoma detection rate in colonoscopic screening of a Chinese population: A prospective study.

Medicine (Baltimore) 2019 Apr;98(15):e15103

Department of Gastroenterology and Hepatology.

Colorectal cancer has high incidence and mortality. Early diagnosis could increase patient survival, but early diagnosis has been poor in China for the past decades. The purpose of this study is to assess the polyp detection rate (PDR) and adenoma detection rate (ADR) by colonoscopy in a Chinese population, and to determine the risk factors for adenoma. Read More

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http://dx.doi.org/10.1097/MD.0000000000015103DOI Listing
April 2019
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Complete Regression of Giant Inflammatory Polyp after Treatment with Adalimumab.

Case Rep Gastrointest Med 2019 7;2019:5347637. Epub 2019 Mar 7.

Lebanese University, School of Medicine, Lebanon.

Giant inflammatory polyps (GIPs) are a rare complication of IBD resulting from chronic regenerative and healing processes leading to a polypoid formation on inflamed mucosa. We reported a case of GIP in a patient with long standing left-sided ulcerative colitis (UC); a well circumscribed sessile GIP was found during a colonoscopy for colorectal cancer screening on a normal colonic mucosa in the cecum. After a severe flare of the left-sided colitis and due to partial response to steroids patient was treated with adalimumab; new colonoscopy after 6 months shows complete disappearance of the GIP previously described. Read More

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https://www.hindawi.com/journals/crigm/2019/5347637/
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http://dx.doi.org/10.1155/2019/5347637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431470PMC
March 2019
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Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study.

Gut 2019 Apr 13. Epub 2019 Apr 13.

Gastroenterology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Background And Aims: Serrated polyposis syndrome (SPS) is associated with an increased risk of colorectal cancer (CRC). International guidelines recommend surveillance intervals of 1-2 years. However, yearly surveillance likely leads to overtreatment for many. Read More

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http://dx.doi.org/10.1136/gutjnl-2018-318134DOI Listing
April 2019
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What is the Hang Up With Optical Diagnosis of Diminutive Colorectal Polyps?

Clin Gastroenterol Hepatol 2019 Apr 10. Epub 2019 Apr 10.

University of Colorado Anschutz Medical Center, Aurora, Colorado, United States; Rocky Mountain Regional Veterans Affairs Hospital, Aurora, Colorado, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193037
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http://dx.doi.org/10.1016/j.cgh.2019.04.017DOI Listing
April 2019
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Cost-Effectiveness of Colonoscopy-Based Colorectal Cancer Screening in Childhood Cancer Survivors.

J Natl Cancer Inst 2019 Apr 13. Epub 2019 Apr 13.

Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

Background: Childhood Cancer Survivors (CCS) are at increased risk of developing colorectal cancer (CRC) compared to the general population, especially those previously exposed to abdominal or pelvic radiation therapy (APRT). However, the benefits and costs of CRC screening in CCS are unclear. In this study, we evaluated the cost-effectiveness of early-initiated colonoscopy screening in CCS. Read More

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http://dx.doi.org/10.1093/jnci/djz060DOI Listing
April 2019
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Laparoscopic Ovarian Transposition Before Pelvic Chemo-radiotherapy in a Young Female Patient with Rectal Cancer - A Video Vignette.

Colorectal Dis 2019 Apr 13. Epub 2019 Apr 13.

Colorrectal Sugery Unit, Donostia University Hospital.

In this video, we describe bilateral laparoscopic ovarian transposition (OT) as an alternative surgical approach for ovarian hormonal function preservation prior to pelvic chemo-radiotherapy for rectal cancer. A 29 years old woman presented with rectal bleeding, progressive tenesmus and frequency of defaecation. Colonoscopy revealed a concentric ulcerated rectal mass and histological examination confirmed the diagnosis of a rectal adenocarcinoma. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/codi.14644
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http://dx.doi.org/10.1111/codi.14644DOI Listing
April 2019
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