13,409 results match your criteria Colonic Obstruction

Ileo-colic lipomatosis complicated by cecum perforation and mimicking acute appendicitis: a case report.

Acta Biomed 2022 Jun 29;93(S1):e2022208. Epub 2022 Jun 29.

S.O.C. Chirurgia Generale, P.O. Santissima Trinità, Cagliari, Italy..

Lipomatosis of the colon is rare in clinical practice although the majority of cases are found incidentally. In rare circumstances, patients may presents with acute complications such as bowel obstruction, intussusception, or perforation. Here we report a case of colonic lipomatosis that present as localized peritonitis mimicking acute appendicitis in a young COVID patient. Read More

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Colorectal carcinoma presenting as spontaneous colocutaneous fistula - A rare case report and review of literature.

Int J Surg Case Rep 2022 Jun 24;96:107346. Epub 2022 Jun 24.

Department of Pathology, Shree Birendra Hospital, Chhauni, Kathmandu 44600, Nepal.

Introduction And Importance: Colon cancer presenting as spontaneous enterocutaneous fistula are rare with only few cases reported in the literature. Such presentation signifies locally advanced disease with poorer outcomes. Enterocutaneous fistula increases morbidity and mortality in cancer and may potentially delay the definitive care. Read More

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Recurrent spontaneous pneumoperitoneum secondary to intestinal dilatation caused by allied disorders of Hirschsprung's disease: a case report.

BMC Gastroenterol 2022 Jun 27;22(1):316. Epub 2022 Jun 27.

Division of General Internal Medicine, Department of Primary Care & Family Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Diseases (Peking Union Medical College Hospital), Beijing, 100730, China.

Background: Allied disorders of Hirschsprung's disease (ADHD) mainly present with bowel obstruction, intestinal dilatation, and chronic constipation, while recurrent spontaneous pneumoperitoneum was rarely reported. We aimed to report a case of recurrent spontaneous pneumoperitoneum caused by ADHD.

Case Presentation: A 59-year-old female patient presented with progressive and severe constipation in the past 30 years. Read More

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Malignant Gastrointestinal Neuroectodermal Tumor: A New Kid on the Block?

J Comput Assist Tomogr 2022 Jun 28. Epub 2022 Jun 28.

From the Department of Abdominal Radiology, The University of Texas MD Anderson Cancer Center.

Abstract: Also referred to as "osteoclast-rich, clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLGT)," malignant gastrointestinal neuroectodermal tumor is a newly described, rare, aggressive sarcoma that commonly arises in the small bowel, stomach, and colon. Histogenesis is likely from an autonomous nervous system-related primitive cell of neural crest origin. The hallmark genetic finding of EWS-CREB1 or EWS-ATF1 fusion transcripts clinches the diagnosis. Read More

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Recurrence-Free Survival Outcomes Based on Novel Classification Combining Lymphovascular Invasion, Perineural Invasion, and T4 Status in Stage II-III Colon Cancer.

Cancer Manag Res 2022 20;14:2031-2040. Epub 2022 Jun 20.

Department of Surgery, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong-si, Gyeonggi, 445-170, Republic of Korea.

Background: T4 tumor, lymphovascular invasion (LVI) and perineural invasion (PNI) are regarded as one of risk factors and associated with poor outcomes in colorectal cancer. The relationship between these three combined risk factors and the prognosis for colon cancer is not yet clear. The purpose of this study was to evaluate the prognostic value of combining the risk factors T4 tumor, LVI, and PNI in stage II-III colon cancer. Read More

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[Delayed gastric emptying after surgery for transverse colon cancer: diagnosis, management and prevention].

P Chi S H Huang

Zhonghua Wei Chang Wai Ke Za Zhi 2022 Jun;25(6):493-499

Department of Colorectal Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, China.

Delayed gastric emptying is a syndrome of gastric motility disorder with slow gastric emptying as the main sign, provided that mechanical factors such as intestinal obstruction and anastomotic stricture are excluded. The incidence of delayed gastric emptying after colon cancer surgery is 1.4%, mainly after transverse colon cancer surgery. Read More

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Metastatic Large Cell Neuroendocrine Carcinoma of the Colon: A Case Report.

Cureus 2022 Jun 19;14(6):e26075. Epub 2022 Jun 19.

Department of Internal Medicine, Wayne State University School of Medicine, Rochester Hills, USA.

Colorectal neuroendocrine tumors are rare entities, with large cell neuroendocrine carcinomas occurring less frequently. We report a case of an 83-year-old male who presented with symptoms of intestinal obstruction. A computed tomography scan of the abdomen and pelvis revealed a high-grade large bowel obstruction secondary to an irregular exophytic soft tissue mass within the ascending colon, with extensive metastatic disease. Read More

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The Prognostic Reliability of Lymphovascular Invasion for Patients with T3N0 Colorectal Cancer in Adjuvant Chemotherapy Decision Making.

Cancers (Basel) 2022 Jun 8;14(12). Epub 2022 Jun 8.

Department of Colon and Rectal Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

Lymphovascular invasion (LVI) is a high-risk feature guiding decision making for adjuvant chemotherapy. We evaluated the prognostic importance and reliability of LVI as an adjuvant chemotherapy indicator in 1634 patients with pT3N0 colorectal cancer treated with curative radical resection between 2012 and 2016. LVI and perineural invasion (PNI) were identified in 382 (23. Read More

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Over-the-catheter endoscope replacement for stenting in patients with inaccessible malignant colonic obstruction with coexisting peritoneal carcinomatosis.

Dig Endosc 2022 Jun 23. Epub 2022 Jun 23.

Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Although a large-caliber endoscope (LCE) is indispensable for through-the-scope placement of a self-expandable metallic stent (SEMS) in patients with malignant colonic obstruction (MCO), inaccessibility of the target obstructing lesion (TOL) by the endoscope is a significant cause of unsuccessful procedures. We herein present a novel salvage procedure when the TOL is not directly accessible by an LCE in conditions such as coexisting peritoneal carcinomatosis involving the colon. The salvage procedure, termed over-the-catheter endoscope replacement (OCER), starts with an ultraslim endoscope suitable for deep insertion beyond a tortuous colon for traversing a guidewire through the TOL. Read More

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Obstructing primary squamous cell carcinoma of caecum: A case report.

Ann Med Surg (Lond) 2022 Jun 6;78:103907. Epub 2022 Jun 6.

Department of Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, India.

Squamous cell carcinoma (SCC) of the colon is a rare malignancy and usually a pathological surprise. Clinical presentation is usually very similar to adeno carcinoma variety. We report a case of a 56 year old male with primary SCC of caecum presenting as small bowel obstruction and managed with surgery and adjuvant chemotherapy. Read More

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Comparison of Oncologic Outcomes Between Incomplete Obstructive Colon Cancer and Non-Obstructive Colon Cancer by Tumor Location.

Front Oncol 2022 6;12:914299. Epub 2022 Jun 6.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Introduction: Obstruction in colon cancer is a well-known risk factor for worse oncologic outcomes. However, studies on differences in survival of patients with incomplete obstructive colon cancer (IOCC) by tumor location are insufficient. Thus, the aim of this study was to compare oncologic outcomes between IOCC and non-obstructive colon cancer (NOCC) according to tumor location. Read More

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Clinico-pathological characteristics of obstructing colorectal cancer and its management outcomes at a tertiary referral center of Eastern Nepal.

BMC Gastroenterol 2022 Jun 21;22(1):303. Epub 2022 Jun 21.

Department of Surgery, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.

Background: The aim of this study is to explore the treatment strategies being followed for patients with obstructing colorectal cancer (OCRC) at our institute and to know the management outcomes.

Methods: This study included 28 patients who were diagnosed with obstructing colorectal cancer (OCRC) either preoperatively or intraoperatively over a period of 5 years.

Results: Most were in the younger age group with mean age of 49. Read More

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High-Grade Colonic Stricture After a Severe Case of COVID-19 Pneumonia.

Am Surg 2022 Jun 21:31348221109811. Epub 2022 Jun 21.

Division of Colon and Rectal Surgery, Department of Surgery, 23387Mayo Clinic, Phoenix, AZ, USA.

Extrapulmonary involvement of coronavirus-19 disease (COVID-19) is being documented and studied at an increasing frequency. Specifically, gastrointestinal involvement is hypothesized to occur due to cellular entry via the ACE2 receptor found in gastrointestinal epithelial cells, causing inflammation and symptoms such as abdominal pain, nausea/vomiting, and diarrhea. We present the case of a 45-year-old female with recent severe COVID-19 infection and early gastrointestinal symptoms who later presented with worsening abdominal pain, nausea, vomiting, and constipation after initial discharge. Read More

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MFE40-the active fraction of Mume Fructus alcohol extract-alleviates Crohn's disease and its complications.

J Ethnopharmacol 2022 Jun 17;296:115465. Epub 2022 Jun 17.

School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China. Electronic address:

Ethnopharmacological Relevance: Mume Fructus (MF) is a well-known traditional Chinese medicine used to treat chronic cough, prolonged diarrhea, and other inflammation-related diseases. We previously confirmed the anti-colitis effect of its ethanol extract on a 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced Crohn's disease (CD) rat model. However, the active ingredients and underlying mechanisms of MF remain unknown. Read More

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Recurrent abdominal distention, colonic ulcer is a cause or a consequence?

Gastroenterology 2022 Jun 15. Epub 2022 Jun 15.

Department of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. Electronic address:

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Pyloric Stenosis: A Rare Manifestation of Crohn's Disease.

J Community Hosp Intern Med Perspect 2022 31;12(1):39-42. Epub 2022 Jan 31.

Department of Gastroenterology, Blanchard Valley Health System, Findlay, OH, USA.

We are presenting a rare case of pyloric stenosis due to Crohn's disease. A 53-year-old woman with prior history of colonic Crohn's disease was admitted to the hospital with gastric outlet obstruction. Esophagogastroduodenoscopy demonstrated pyloric stenosis and biopsy was consistent with Crohn's disease. Read More

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January 2022

Perioperative and oncologic outcomes of interval colectomy performed by acute care surgeons after stenting as a bridge to surgery for left-sided malignant colonic obstruction are non-inferior to the outcomes of colorectal surgeons in the elective setting: single center experience.

Eur J Trauma Emerg Surg 2022 Jun 16. Epub 2022 Jun 16.

Head-in-Chief. General, Digestive and Transplantation Surgery Department, University Regional Hospital, Malaga, Spain.

Purpose: To analyze if perioperative and oncologic outcomes with stenting as a bridge to surgery (SEMS-BS) and interval colectomy performed by acute care surgeons for left-sided occlusive colonic neoplasms (LSCON) are non-inferior to those obtained by colorectal surgeons for non-occlusive tumors of the same location in the full-elective context.

Methods: From January 2011 to January 2021, patients with LSCON at University Regional Hospital in Málaga (Spain) were directed to a SEMS-BS strategy with an interval colectomy performed by acute care surgeons and included in the study group (SEMS-BS). The control group was formed with patients from the Colorectal Division elective surgical activity dataset, matching by ASA, stage, location and year of surgery on a ratio 1:2. Read More

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[Obstructed colon cancer: which strategy in 2022?]

Rev Med Suisse 2022 Jun;18(786):1192-1199

Service de chirurgie viscérale, Département de chirurgie, Centre hospitalier universitaire vaudois et Université de Lausanne, 1011 Lausanne.

The key priority for obstructed colon cancer (OCC) is urgent resolution of the large bowel obstruction with ideally no compromise of oncological outcomes and low initial and permanent ostomy rates. Proactive management is pivotal to decrease the risk of perforation and septic shock. Staged procedures have an important place to provide optimal treatment and offer similar treatment and outcomes as in the elective setting. Read More

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Evaluation and treatment of the post pull-through Hirschsprung patient who is not doing well; Update for 2022.

Semin Pediatr Surg 2022 Apr 18;31(2):151164. Epub 2022 Apr 18.

Division of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, DC, United States. Electronic address:

After operative intervention for Hirschsprung disease (HD) a child should thrive, be fecally continent, and avoid recurrent episodes of abdominal distention and enterocolitis. This is unfortunately not the case for a significant number of patients who struggle following their pull-through procedure. Many clinicians are puzzled by these outcomes as they can occur in patients who they believe have had a technically satisfactory described operation. Read More

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[Ogilvie´s syndrome as a rare complication of lumbar stenosis surgery: report of two cases and literature review].

Pan Afr Med J 2022 4;42. Epub 2022 May 4.

Service de Neurochirurgie, Centre Hospitalier Universitaire, Guadeloupe, France.

Ogilvie´s syndrome is an acute colonic pseudo-obstruction, characterized by massive colonic distension in the absence of mechanical cause. It is a very rare pathology after spinal surgery. We report two cases in the neurosurgery department of the University Hospital of Guadeloupe. Read More

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Acute Scrotal Abdomen: An Epitome of Negligence in Rural India.

Cureus 2022 May 6;14(5):e24784. Epub 2022 May 6.

General Surgery, Dr. Sampurnanand Medical College, Jodhpur, IND.

An inguinoscrotal hernia is considered to be giant when it passes beyond the midpoint of the thigh in a standing position. It is a rare condition that can lead to complications such as obstruction and perforation. Here, we present the case of a 35-year-old male who was diagnosed with a giant inguinoscrotal hernia with transverse colon perforation peritonitis. Read More

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Detection methods of synchronous colorectal lesions in proximal colon for patients with obstructive colorectal cancer: a literature review.

Expert Rev Gastroenterol Hepatol 2022 Jun 13:1-9. Epub 2022 Jun 13.

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, Peking, China.

Introduction: Colorectal cancer holds a high morbidity and mortality rate. As a common method for colorectal cancer detection, colonoscopy has difficulty in passing through the malignant stenosis in patients with obstructive colorectal cancer, which results in incomplete detection and missed diagnosis. The missed synchronous lesions increase the risk of metachronous cancer. Read More

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Short-term Outcomes of Elective Surgery Following Self-Expandable Metallic Stent and Neoadjuvant Chemotherapy in Patients With Left-Sided Colon Cancer Obstruction.

Dis Colon Rectum 2022 May 30. Epub 2022 May 30.

General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Background: Colonic stenting reduces morbidity and stoma formation for left-sided colon cancer obstruction, and prolonged interval between stenting and surgery with neoadjuvant chemotherapy administered might result in a lower stoma rate and tumor reduction.

Objective: To evaluate the short-term outcomes of elective surgery following colonic stenting compared with elective surgery following colonic stenting and neoadjuvant chemotherapy in patients with left-sided colon cancer obstruction.

Design: A prospective multicenter cohort study. Read More

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A Novel Technique with Ileal Mesentery to Reconstruct the Pelvic Peritoneum after Pelvic Dissection with End-Colostomy for Rectal Cancer.

Dis Colon Rectum 2022 May 25. Epub 2022 May 25.

Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

Background: After abdominoperineal resection, low anterior resection, and end-colostomy for lower rectal cancer, it is necessary to reconstruct the pelvic peritoneum to avoid small bowel obstruction, perineal hernia, and radiation enteritis in patients for whom postoperative radiotherapy is planned. However, pelvic peritoneal closure is technically difficult in patients who lack enough peritoneum to cover the defect or have received neoadjuvant radiation and have a rigid pelvis.

Impact Of Innovation: The impact of this innovation is to reconstruct the pelvic peritoneum with the distal ileal mesentery laparoscopically. Read More

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FuZhengHuaYuJiangZhuTongLuoFang Prescription Modulates Gut Microbiota and Gut-Derived Metabolites in UUO Rats.

Front Cell Infect Microbiol 2022 20;12:837205. Epub 2022 May 20.

Department of Nephrology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Background: Alteration of intestinal flora and metabolites is closely related to chronic kidney disease (CKD) across early to advanced stages. FuZhengHuaYuJiangZhuTongLuoFang prescription (FZHY) is a Chinese herb that has been proven to effectively treat CKD, but the underlying mechanism is not clear.

Methods: Rats were subjected to intragastric treatment with FZHY 7, 14, and 21 days after unilateral ureteral obstruction (UUO) surgery, and kidney tissue, colon tissue, serum, and stool samples were collected. Read More

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Oxaliplatin-Induced Sinusoidal Obstruction Syndrome Masquerading as Colorectal Liver Metastasis: A Case Report.

J Gastrointest Cancer 2022 Jun 6. Epub 2022 Jun 6.

Department of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Ernest Borges Road, Parel, Mumbai, 400012, India.

Introduction: Oxaliplatin-based chemotherapy is commonly used in adjuvant treatment of colon cancer as well as in neoadjuvant setting in patients with liver metastases. However oxaliplatin can cause damage to non-tumor bearing liver which presents as sinusoidal obstructive syndrome (SOS). These changes are difficult to differentiate from metastasis clinic-radiologically and manifests as sinusoidal dilatation, peliosis and nodular regenerative hyperplasia. Read More

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Risk factors for metachronous peritoneal carcinomatosis after radical resection for patients with nonmetastatic pT3-4 colon cancer.

J Surg Oncol 2022 Jun 4. Epub 2022 Jun 4.

Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Background: Patients with nonmetastatic pT3-4 colon cancers are prone to develop metachronous peritoneal carcinomatosis (mPC). Risk factors for mPC and the influence of mutant kirsten rat sarcoma viral oncogene (KRAS)/neuroblastoma rat sarcoma (NRAS)/v-raf murine sarcoma viral oncogene homolog B1 (BRAF) and DNA mismatch repair (MMR) status on mPC remain to be described in these patients.

Method: All enrolled patients were identified from the prospectively collected colorectal cancer database of a tertiary referral hospital between 2013 and 2018. Read More

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Differences in clinical outcomes according to the time interval between the bridge to surgery stenting and surgery for left-sided malignant colorectal obstruction.

World J Surg Oncol 2022 Jun 3;20(1):178. Epub 2022 Jun 3.

Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-ku, Gwangju, 501-757, Republic of Korea.

Background: Self-expandable metal stent (SEMS) placement is commonly used as a bridge to surgery (BTS) for left-sided malignant colorectal obstruction (MCO). However, the optimal time interval between BTS stenting and surgery for left-sided MCO is unclear, and the results of previous studies are conflicting. This study aimed to determine the differences in clinical outcomes according to the time interval between BTS stenting and surgery in left-sided MCO. Read More

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Giant Proximal Right Colon Submucosal Hematoma Leading to a Large Bowel Obstruction.

Cureus 2022 Apr 29;14(4):e24599. Epub 2022 Apr 29.

General Surgery, Texas Tech University Health Sciences Center, Amarillo, USA.

A 41-year-old female with a previous history of chronic obstructive pulmonary disease (COPD) and polycythemia presented to the emergency department with worsening shortness of breath and cough which progressed to respiratory distress requiring mechanical ventilation. During her hospital stay, she developed abdominal distention followed by a fever and a four-point decrease in hemoglobin. A non-contrasted abdominopelvic CT scan was ordered which showed a very large retroperitoneal hematoma adjacent to the right colon with subtle active bleeding. Read More

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Hirschsprung-Associated Enterocolitis: Transformative Research from Bench to Bedside.

Eur J Pediatr Surg 2022 Jun 1. Epub 2022 Jun 1.

Department of General Surgery, Capital Institute of Pediatrics, Beijing, Beijing, China.

Hirschsprung disease (HSCR) is a congenital disease that is characterized by the absence of intrinsic ganglion cells in the submucosal and myenteric plexuses of the distal colon and is the most common cause of congenital intestinal obstruction. Hirschsprung-associated enterocolitis (HAEC) is a life-threatening complication of HSCR, which can occur either before or after surgical resection of the aganglionic bowel. Even though HAEC is a leading cause of death in HSCR patients, its etiology and pathophysiology remain poorly understood. Read More

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