8,025 results match your criteria Colloids and surfaces. B Biointerfaces[Journal]


Dual drug loaded liposome bearing apigenin and 5-Fluorouracil for synergistic therapeutic efficacy in colorectal cancer.

Colloids Surf B Biointerfaces 2019 Apr 16;180:9-22. Epub 2019 Apr 16.

School of Medical Science and Technology, Indian Institute of Technology, Kharagpur, 721302, India. Electronic address:

Multidrug-based combinatorial therapeutic regiments which target multiple pathways simultaneously are being utilized as a therapeutic strategy of choice due to reduction in toxicity profile and enhancement of therapeutic index of the individual drugs. 5-Fluorouracil is a clinically approved drug which has limited response rate in the realm of colorectal cancer amelioration, hence our study aims to improve its efficacy by aiming the simultaneous delivery of 5-Flurouracil and apigenin which is naturally occurring flavone abundantly present in fruit and vegetables through a single liposome to combat and control colorectal cancer effectively in-vitro and in-vivo. The liposomal nanocarrier bearing the anti-tumorigenic agent apigenin was designed in this study in order to improve the bioavailability of the flavone while at the same time achieve combinatorial drug regime with 5- Fluorouracil. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.035DOI Listing
April 2019
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Improved electrocatalytic activity of Au@FeO magnetic nanoparticles for sensitive dopamine detection.

Colloids Surf B Biointerfaces 2019 Apr 16;180:1-8. Epub 2019 Apr 16.

Electroorganic Division, CSIR-Central Electrochemical Research Institute, Karaikudi 630003, India. Electronic address:

Substantially, noble metals are important for the development of low-cost, sensitive, selective, superior performance, and portable electrochemical sensors. Herein, we describe gold (Au) nanoparticles (NPs) systematically decorated with magnetic FeO nanocomposites on the fabrication of sensitive dopamine sensor is described. Magnetic Au@FeO nanocomposites were prepared by reducing HAuCl on the surfaces of FeO nanoparticles. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.034DOI Listing

Protein corona variation in nanoparticles revisited: A dynamic grouping strategy.

Colloids Surf B Biointerfaces 2019 Apr 3;179:505-516. Epub 2019 Apr 3.

Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran; Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Bio-nano interface investigation models are mainly based on the type of proteins present on corona, bio-nano interaction responses and the evaluation of final outcomes. Due to the extensive diversity in correlative models for investigation of nanoparticles biological responses, a comprehensive model considering different aspects of bio-nano interface from nanoparticles properties to protein corona fingerprints appeared to be essential and cannot be ignored. In order to minimize divergence in studies in the era of bio-nano interface and protein corona with following therapeutic implications, a useful investigation model on the basis of RADAR concept is suggested. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.003DOI Listing

Simultaneous controlled release of 5-FU, DOX and PTX from chitosan/PLA/5-FU/g-C3N4-DOX/g-C3N4-PTX triaxial nanofibers for breast cancer treatment in vitro.

Colloids Surf B Biointerfaces 2019 Apr 13;179:495-504. Epub 2019 Apr 13.

Young Researchers & Elite Club, Tehran North Branch, Islamic Azad University, Tehran, Iran. Electronic address:

In the present study, the tri-layer nanofibers were synthesized via triaxial electrospinning process to control the sustained delivery of Doxorubicin (DOX), Paclitaxel (PTX) and 5- fluorouracil (5-FU) anticancer drugs from nanofibers. The 5-FU molecules were incorporated into the core solution (chitosan/polyvinyl alcohol (CS/PVA)) to fabricate the CS/PVA/5-FU inner layer of nanofibers. The intermediate layer was prepared from poly(lactic acid)/chitosan (PLA/CS) nanofibers. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.026DOI Listing

Vesicle formation by ultrashort alkyl-phosphonic acids and serine in aqueous solutions.

Colloids Surf B Biointerfaces 2019 Mar 27;179:488-494. Epub 2019 Mar 27.

College of Food & Biology Engineering, Zhejiang Gongshang University, Hangzhou, Zhejiang 310035, China. Electronic address:

Vesicles possess unique biofilm structures and offer biomimetic advantages for drug and gene delivery. Herein, we report the spontaneous vesicle formation from ultrashort alkyl-phosphonic acids in the presence of amino acids. The aggregation characteristics and self-assembly structures of vesicles in aqueous solution were investigated by using dynamic light scattering, zeta potential, and cryo-transmission electron microscopy. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.055DOI Listing
March 2019
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Superoxide dismutase in nanoarchaeosomes for targeted delivery to inflammatory macrophages.

Colloids Surf B Biointerfaces 2019 Mar 28;179:479-487. Epub 2019 Mar 28.

Nanomedicine Research & Development Center, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Saenz Peña 352, Bernal, B1876BXD, Argentina. Electronic address:

Oxidative stress plays an essential role in the pathogenesis and progression of inflammatory bowel disease. Co-administration of antioxidants and anti-inflammatory drugs has shown clinical benefits. Due to its significant reactive oxygen species (ROS) scavenging ability, great interest has been focused on superoxide dismutase (SOD) for therapeutic use. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.061DOI Listing
March 2019
2 Reads

Mussel-inspired hybrid coating functionalized porous hydroxyapatite scaffolds for bone tissue regeneration.

Colloids Surf B Biointerfaces 2019 Apr 14;179:470-478. Epub 2019 Apr 14.

Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, 610031, China.

The scaffold for bone tissue engineering should possess proper porosity, adequate mechanical properties, cell affinity for cell attachment, and the capability to bind bioactive agents to induce cell differentiation. In this study, we successfully prepared a porous hydroxyapatite (HA) scaffold that is functionalized by poly(L-lysine)/polydopamine (PLL/PDA) hybrid coating. The PLL/PDA coating takes advantages of the high protein and cell affinity of PDA, as well as the biodegradability of PLL. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.024DOI Listing

A mussel-inspired carboxymethyl cellulose hydrogel with enhanced adhesiveness through enzymatic crosslinking.

Colloids Surf B Biointerfaces 2019 Mar 21;179:462-469. Epub 2019 Mar 21.

State Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai, 200237, China; Engineering Research Center of Materials Chemical Engineering of Xinjiang Bingtuan, Key Laboratory of Materials Chemical Engineering of Xinjiang Uygur Autonomous Region, Shihezi University, Shihezi, 832000, China. Electronic address:

In order to replace conventional sutures in wound closing applications, favorable hydrogels with strong wet tissue adhesion and biocompatibility have attracted considerable attention. Herein, inspired by mussel adhesive protein, a series of dopamine modified carboxymethyl cellulose (CMC-DA) hydrogels were prepared in situ using enzymatic crosslinking in the presence of horseradish peroxidase (HRP) and HO. The biomimetic CMC-DA hydrogel exhibited about 6-fold enhanced wet tissue adhesion strength (28. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.044DOI Listing

Facile fabrication of PEG-coated PLGA microspheres via SPG membrane emulsification for the treatment of scleroderma by ECM degrading enzymes.

Colloids Surf B Biointerfaces 2019 Apr 14;179:453-461. Epub 2019 Apr 14.

Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Department of Bioengineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. Electronic address:

We developed a facile fabrication method for preparing poly(ethylene glycol)(PEG)-coated poly (lactic-co-glycolic acid) (PLGA) microspheres with homogeneous size distribution via a combination of mPEG-b-PLGA and Shirasu Porous Glass membrane emulsification. Subsequently, extracellular matrix (ECM) degrading enzymes, collagenase (COLase) or hyaluronidase (HAse) were loaded into the microspheres. The obtained microspheres exhibited a sustained release of COLase or HAse over 10 days. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193025
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http://dx.doi.org/10.1016/j.colsurfb.2019.04.028DOI Listing
April 2019
4 Reads

Preparation of letrozole dispersed pHEMA/AAm-g-LDPE drug release system: In-vitro release kinetics for the treatment of endometriosis.

Colloids Surf B Biointerfaces 2019 Apr 8;179:445-452. Epub 2019 Apr 8.

King Saud University, Advanced Manufacturing Institute, Riyadh, 11421, Saudi Arabia.

This paper focuses on the development of a drug delivery system for systemically controlled release of a poorly soluble drug, letrozole. The work meticulously describes the preparation and characterizations of 2-hydroxyethyl methacrylate (HEMA) polymerization onto hydrophilic acrylamide grafted low-density polyethylene (AAm-g-LDPE) surface for targeted drug release system. The surface morphology and thickness measurement of coated pHEMA layer were measured using scanning electron microscopy (SEM). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193023
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http://dx.doi.org/10.1016/j.colsurfb.2019.04.014DOI Listing
April 2019
5 Reads

Unraveling the solubilization and cytotoxicity study of poorly water-soluble anti-inflammatory drug in aqueous Gemini surfactants solution with physicochemical characterization and simulation study.

Colloids Surf B Biointerfaces 2019 Mar 28;179:437-444. Epub 2019 Mar 28.

Applied Chemistry Department, Sardar Vallabhbhai National Institute of Technology (SVNIT), Ichchhanath, Surat, 395 007, Gujarat, India. Electronic address:

This work investigates the use of quaternary ammonium based Gemini surfactants (GS) to examine the solubilization and stabilization of a poorly water soluble anti-inflammatory drug Diclofenac (Df). Here we demonstrate the effect of pH on the suspension profile of Df release where it exhibits maximum solubility and absorbance at pH = 10. Interaction process of such cationic GS with Df have been systematically characterized using tensiometry and UV-vis spectroscopy techniques from pre-micellar to post-micellar regions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193020
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.059DOI Listing
March 2019
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Corrosion resistance and antibacterial properties of hydroxyapatite coating induced by gentamicin-loaded polymeric multilayers on magnesium alloys.

Colloids Surf B Biointerfaces 2019 Apr 13;179:429-436. Epub 2019 Apr 13.

College of Materials Science and Engineering, Chongqing University of Technology, Chongqing, 400065, China.

As a result of their good biocompatibility, bioactivity, and mechanical properties, magnesium (Mg) alloys have received considerable attention as next generation biodegradable implants. Herein, in order to achieve a proper degradation rate and good antibacterial ability, we reported a novel hydroxyapatite coating induced by gentamicin (GS)-loaded polymeric multilayers for the surface treatment of the Mg alloy. The coating was characterized by X-ray diffraction, fourier transform infrared spectroscopy and scanning electron microscopy. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.029DOI Listing

Interaction between charged lipid vesicles and point- or rod-like trivalent ions.

Colloids Surf B Biointerfaces 2019 Feb 20;178:525-529. Epub 2019 Feb 20.

Faculty of Health Sciences, University of Ljubljana, Zdravstvena 5, SI-1000 Ljubljana, Slovenia. Electronic address:

This work examines the influence of the charge distribution of trivalent cations on their interaction with soft anionic particles, using a combination of experimental measurements and theoretical modelling. In particular, we perform electrophoresis measurements to determine the zeta-potential of anionic liposomes in the presence of spermidine and lanthanum cations. We work in a range of electrolyte concentration where a reversal in the electrophoretic mobility of the liposomes is expected; however, unlike the case of lanthanum cations, spermidine does not induce mobility reversal of liposomes. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.02.010DOI Listing
February 2019

Neuroprotective effect of Dictyopteris divaricata extract-capped gold nanoparticles against oxygen and glucose deprivation/reoxygenation.

Colloids Surf B Biointerfaces 2019 Mar 29;179:421-428. Epub 2019 Mar 29.

Biomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea; Department of Laboratory Medicine, Pusan National University Hospital, Busan 49241, Republic of Korea.

Combination therapy remains a promising approach to ameliorate cerebral ischemia injury. Nevertheless, the primary mechanism of the neuroprotective properties of Dictyopteris divaricata extract-capped gold nanoparticles (DD-GNPs) is not completely understood. DD-GNPs displayed maximum absorption at 525 nm and a diameter of 62. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.066DOI Listing

Quantification of drugs encapsulated in liposomes by H NMR.

Colloids Surf B Biointerfaces 2019 Mar 31;179:414-420. Epub 2019 Mar 31.

Centre of Biological Engineering, University of Minho, Braga, Portugal. Electronic address:

Liposomes are one of the most important and extensively studied drug delivery system due to their ability to encapsulate different kinds of drugs. Exploiting the advantages of H Nuclear Magnetic Resonance (NMR) spectrometry, we established a rapid and easy method for quantification of drugs encapsulated in liposomes. An internal standard, pyridine, was used for quantitative determination of drug concentration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193018
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.039DOI Listing
March 2019
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In-vitro blood and vascular compatibility of sirolimus-eluting organic/inorganic hybrid stent coatings.

Colloids Surf B Biointerfaces 2019 Apr 9;179:405-413. Epub 2019 Apr 9.

Research Institute of Advanced Manufacturing Technology, Korea Institute of Industrial Technology, Incheon, 21999, Republic of Korea. Electronic address:

The surface characteristics of coronary stents play a pivotal role in inhibiting in-stent restenosis and late-stent thrombosis. In this study, a sol-gel-derived silica xerogel-chitosan hybrid coating was applied to Co-Cr stent and was reported, for the first time, as a biocompatible drug delivery tool in vascular stent application. A dense and uniform chitosan-silica xerogel hybrid coating (<1-μm thick) was applied on bare Co-Cr material. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.018DOI Listing

Formulation, clinical and histopathological assessment of microemulsion based hydrogel for UV protection of skin.

Colloids Surf B Biointerfaces 2019 Apr 8;179:393-404. Epub 2019 Apr 8.

Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, P.O. Box: 91388-13944, Islamic Republic of Iran.

The aim of this study was to prepare a microemulsion based hydrogel containing sesame oil and evaluate its topical application in preventing the harmful effects of UV radiation on the guinea pig's skin using histopathologic and clinical findings. Sesame oil with high antioxidant content and unique chemical and physiological properties is a suitable candidate for the evolution of UV protection on skin. Applying this natural oil in microemulsion formulation containing particles with nanometer size can enhance its efficacy. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.015DOI Listing

A novel oil-based suspension of a micro-environmental, pH-modifying solid dispersion for parenteral delivery: Formulation and stability evaluation.

Colloids Surf B Biointerfaces 2019 Apr 3;179:382-392. Epub 2019 Apr 3.

The Department of Veterinary Parasitology, College of Veterinary Medicine, China Agricultural University, Hai Dian District, Beijing, 100193, China. Electronic address:

The objective of this study was to evaluate a novel oil-based suspension as a potential parenteral drug delivery system for drugs with poor water solubility. Most of the new active pharmaceutical ingredients are weak acid or basic drugs with pH-dependent solubility. To limit this dependence, use of micro-environmental pH-modifying solid dispersions (micro pHm SD) has been proved to increase the bioavailability of these drugs. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.001DOI Listing

The effect of salts in aqueous media on the formation of the BSA corona on SiO nanoparticles.

Colloids Surf B Biointerfaces 2019 Apr 6;179:374-381. Epub 2019 Apr 6.

Department of Chemical and Biochemical Engineering, 4133 Seamans Center for the Engineering Arts and Sciences, The University of Iowa, Iowa City, IA, USA. Electronic address:

Protein-nanoparticle interactions are garnering attention due to their potential impacts on human health and environmental contamination. The colloidal properties of nanoparticles (NPs) in aqueous media may differ in the presence of natural materials such as salts and proteins. In this study, the interactions between bovine serum albumin (BSA) and fumed hydrophilic silicon dioxide (SiO) NPs were studied in aqueous solutions under variable pH or ion composition. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.012DOI Listing

Strontium-incorporated mineralized PLLA nanofibrous membranes for promoting bone defect repair.

Colloids Surf B Biointerfaces 2019 Apr 6;179:363-373. Epub 2019 Apr 6.

College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai, 201620, China. Electronic address:

Mineralized scaffolds, which are fabricated by electrodeposition, mimic the chemistry of natural bone and have attracted a great amount of attention due to their rapid and simple production. In this study, mineralized electrospun polylactic acid (PLLA) nanofibrous membranes containing different amounts of strontium (Sr) were fabricated by an electrodeposition method for potential use in bone regeneration applications. In vitro assays, including cell proliferation and osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells (BMSCs) grown on these membranes and in vivo cranial bone defect repair assays, were carried out. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.011DOI Listing
April 2019
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A facile strategy to fabricate a pH-responsive mesoporous silica nanoparticle end-capped with amphiphilic peptides by self-assembly.

Colloids Surf B Biointerfaces 2019 Mar 11;179:352-362. Epub 2019 Mar 11.

Center of Clinical Laboratory Medicine of Zhongda Hospital, Southeast University, Nanjing, 210009, China; Medical School, Southeast University, Nanjing, 210009, China. Electronic address:

A facile strategy with no modification processes was demonstrated to fabricate a pH-responsive end-capped mesoporous silica nanoparticle (MSN)-based drug delivery system (DDS). The simple but smart nanovalve systems were constructed by the self-assembly behavior of unbonded peptide-based amphiphile (P45) in the presence of Doxorubicin hydrochloride (Dox). A series of characterizations confirmed that the DDSs had been successfully fabricated. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.019DOI Listing
March 2019
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Small gold nanorods-loaded hybrid albumin nanoparticles with high photothermal efficacy for tumor ablation.

Colloids Surf B Biointerfaces 2019 Apr 1;179:340-351. Epub 2019 Apr 1.

School of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 16419, Republic of Korea. Electronic address:

Photothermal therapy using gold nanorods (AuNRs) has gained great attention for cancer therapy because AuNRs emit heat and induce tumor cell death responding to the near infrared light. However, the anticancer efficiency of AuNRs alone is undermined by its poor in vivo stability and potential toxicity. The prime purpose of this study was to send more AuNRs into tumors to more fully ablate them. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193021
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.068DOI Listing
April 2019
3 Reads

In situ synthesis of magnetic iron oxide nanoparticles in chitosan hydrogels as a reaction field: Effect of cross-linking density.

Colloids Surf B Biointerfaces 2019 Apr 3;179:334-339. Epub 2019 Apr 3.

Graduate School of Biomedical Engineering, Tohoku University, Sendai, Japan.

Magnetic iron oxides such as magnetite and γ-hematite have attracted considerable attention as thermoseeds for hyperthermia treatment because of their ability to generate heat under an alternating magnetic field. Control of the particle size and their combination with biocompatible polymers are expected to be beneficial for optimization of the nanoparticles. These processes can be accomplished through the synthesis of magnetite in gels, as the network structure of the polymer gel can control the grain growth of the magnetite. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193022
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http://dx.doi.org/10.1016/j.colsurfb.2019.04.004DOI Listing
April 2019
4 Reads

Carbamide peroxide nanoparticles for dental whitening application: Characterization, stability and in vivo/in situ evaluation.

Colloids Surf B Biointerfaces 2019 Apr 4;179:326-333. Epub 2019 Apr 4.

Post Graduation Program in Pharmaceutical Sciences, Federal University of Santa Catarina (UFSC), Brazil.

Carbamide peroxide is the popular home dental whitening agent. However, it has critical stability. Nanoparticles have been applied to develop products with advantages properties as better efficacy and stability increase. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.006DOI Listing

Characterization and synergistic antibacterial potential of green synthesized silver nanoparticles using aqueous root extracts of important medicinal plants of Pakistan.

Colloids Surf B Biointerfaces 2019 Apr 8;179:317-325. Epub 2019 Apr 8.

Biotechnology Program, Department of Environmental Sciences, COMSATS University Islamabad, Abbottabad Campus, 22060, Abbottabad, Pakistan. Electronic address:

In the past few years, biologically synthesized silver nanoparticles (AgNPs) have been standout amongst the most utilized nanoparticles both in the field of therapeutics and clinical practices. Therefore, the current study aimed to synthesize AgNPs for the first time using aqueous root extracts of important plants of Pakistan i.e. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.016DOI Listing

Enhanced osteogenic differentiation of bone mesenchymal stem cells on magnesium-incorporated titania nanotube arrays.

Colloids Surf B Biointerfaces 2019 Apr 8;179:309-316. Epub 2019 Apr 8.

Institute of Biology and Medicine, College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, 430081, China. Electronic address:

Although titanium and its alloys have been widely used as implants in orthopaedics and dentals, it is still a challenge to realize excellent bioactivity of titanium surface. In this report, magnesium ion incorporated titania nanotube arrays (MgNT) was fabricated on Ti surface through electrochemical anodization and hydrothermal treatment. The magnesium loading capacity and release kinetics were controlled by modulating the conditions in the hydrothermal treatment process. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193023
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http://dx.doi.org/10.1016/j.colsurfb.2019.04.013DOI Listing
April 2019
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Biomimetic mineralisation of eggshell membrane featuring natural nanofiber network structure for improving its osteogenic activity.

Colloids Surf B Biointerfaces 2019 Apr 4;179:299-308. Epub 2019 Apr 4.

Biomaterial Research Laboratory, Department of Material Science and Engineering, College of Chemistry and Materials, Jinan University, Guangzhou, 510632, PR China; Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Guangzhou, 510632, PR China.

Designing reasonably priced bioactive organic-inorganic hybrid materials featuring osteogenic activity has received a significant interest in the bone tissue engineering field. In this study, eggshell membrane (ESM), which consists mostly of proteins exhibiting fibrous network structure, was utilised innovatively as a template to prepare eggshell membrane/hydroxyapatite (ESM-HA) composites using a versatile biomimetic mineralisation technique. In addition, the surface morphology and composition, hydrophilicity, crystallinity, and thermal stability of both sides of ESM and ESM-HA composites were systematically studied. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.009DOI Listing
April 2019
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A novel non-enzymatic HO sensor using ZnMnO microspheres modified glassy carbon electrode.

Colloids Surf B Biointerfaces 2019 Apr 4;179:293-298. Epub 2019 Apr 4.

College of Sciences, Shanghai University, Shanghai, 200444, PR China. Electronic address:

With a facile solvothermal technique, ZnMnO microspheres were synthesized in this work, which were used as enzyme mimics for the electrocatalytic reduction of HO. The morphology, crystal phase and structure of the ZnMnO microspheres underwent characterization under X-ray diffraction spectroscopy, Raman spectroscopy, energy-dispersive spectroscopy, and scanning electron microscopy. The synthesized ZnMnO microspheres showed an average diameter of 2 μm with great crystallinity, and exhibited excellent catalytical activity towards HO electroreduction in alkaline media. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.008DOI Listing
April 2019
4 Reads

Casein nanomicelle as an emerging biomaterial-A comprehensive review.

Colloids Surf B Biointerfaces 2019 Mar 25;179:280-292. Epub 2019 Mar 25.

School of Pharmacy, Monash University, Bandar Sunway, Malaysia; Faculty of Pharmacy, DIT University, Dehradun, India; Global Asia in The 21st Century (GA21) Multidisciplinary Research Platform Monash University Bandar Sunway Malaysia. Electronic address:

Casein nanomicelles, a major fraction of milk protein, are emerging as a novel drug delivery system owing to their various structural and functional properties. Casein is further divided into α-, β- and κ-casein, and to date various models have been proposed to describe casein structure, but still no definite structure presenting a detailed assembly of the casein micelle has been found. Thus far, the submicellar model and Horne and Holt model are the most accepted models. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.051DOI Listing

One-pot reactive electrospinning of chitosan/PVA hydrogel nanofibers reinforced by halloysite nanotubes with enhanced fibroblast cell attachment for skin tissue regeneration.

Colloids Surf B Biointerfaces 2019 Mar 27;179:270-279. Epub 2019 Mar 27.

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

In this study, in situ glyoxal crosslinked chitosan/poly (vinyl alcohol) (PVA) hydrogel nanofibers reinforced with halloysite nanotubes (HNT) were prepared by the electrospinning method without needing post-treatment for stabilization of the nanofibers in aqueous media. FTIR spectroscopy approved the formation of acetal bonds between glyoxal and hydroxyl groups of PVA and chitosan. Morphological studies by SEM/EDX and TEM in accordance with XRD patterns proved that HNT was successfully incorporated into the crosslinked chitosan/PVA nanofibers. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.054DOI Listing
March 2019
2 Reads

Organic-inorganic nanocomposites fabricated via functional ionic liquid as the bridging agent for Laccase immobilization and its application in 2,4-dichlorophenol removal.

Colloids Surf B Biointerfaces 2019 Apr 3;179:260-269. Epub 2019 Apr 3.

State Key Laboratory of Materials-Oriented Chemical Engineering, School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 210009, China; Shandong Key Laboratory of Water Pollution Control and Resource Reuse, China. Electronic address:

In this study, organic-inorganic nanocomposite including mesoporous silica SBA-15 and chitosan was combined using carboxyl-functionalized ionic liquid as the bridging agent (SBA-CIL-CS), and which was characterized by scanning electron microscope, Fourier transform infrared spectroscopy, thermogravimetric analysis, and nitrogen adsorption-desorption isotherms. Thus prepared nanocomposite was applied to laccase immobilization via physical adsorption (SBA-CIL-CS-Lac) and utilized in 2,4-dichlorophenol (2,4-DCP) removal for the first time. SBA-CIL-CS-Lac showed relatively high immobilization efficiency, activity retention (75. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.002DOI Listing

Albumin-MnO gated hollow mesoporous silica nanosystem for modulating tumor hypoxia and synergetic therapy of cervical carcinoma.

Colloids Surf B Biointerfaces 2019 Apr 1;179:250-259. Epub 2019 Apr 1.

Department of Gynecology, The First People's Hospital of Yunnan Province, Kunming University of Science and Technology, Kunming, PR China. Electronic address:

Currently, some approaches in cancer therapy have gradually shifted from a focus on monotherapy to combined therapy, which results in considerable superadditive therapeutic effects. Herein, bovine serum albumin integrated manganese dioxide nanoparticles (BSA-MnO) was synthesized via a biomineralization strategy. Then, the BSA-MnO nanoparticles was anchored on the surface of the chemotherapeutic drug doxorubicin (DOX) and photosensitizer chlorine e6 (Ce6) co-loaded hollow mesoporous silica nanospheres (BSA-MnO@HMSNs-DOX-Ce6, BMHDC) through the formation of disulfide bonds. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.070DOI Listing
April 2019
1 Read

Evaluation of the biocompatibility and skin hydration potential of vitamin E-loaded lipid nanosystems formulations: In vitro and human in vivo studies.

Colloids Surf B Biointerfaces 2019 Apr 3;179:242-249. Epub 2019 Apr 3.

UCIBIO, REQUIMTE, Laboratory of Pharmaceutical Technology/Centre of Research in Pharmaceutical Sciences, Faculty of Pharmacy, Porto University, Porto, Portugal; FP-ENAS (UFP Energy, Environment and Health Research Unit), CEBIMED (Biomedical Research Centre), Faculty of Health Sciences, Fernando Pessoa University, Porto, Portugal. Electronic address:

Lipid-based nanosystems, such as nanostructured lipid carriers (NLC) and nanoemulsions (NE) have been described as promising alternatives to conventional formulations for increase skin hydration. Besides, these systems have been used as efficient vehicles for lipophilic molecules that improve skin properties (e.g. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.036DOI Listing
April 2019
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Ionic strength for tailoring the synthesis of monomodal stealth cationic liposomes in microfluidic devices.

Colloids Surf B Biointerfaces 2019 Mar 27;179:233-241. Epub 2019 Mar 27.

University of Campinas, UNICAMP, School of Chemical Engineering, PO BOX 6066, 13086-090, Campinas, SP, Brazil. Electronic address:

In this work, we describe a hydrodynamic flow-focusing microfluidic process to produce stealth cationic liposomes (SCL), stabilized with poly(ethylene glycol) (PEG), with uniform and reproducible features. Through cryogenic transmission electron microscopy (cryo-TEM) characterization and real-time monitoring, we verified the formation of multi-sized lipid self-aggregates, which can be attributed to micelles formation. These structures tend to undergo deposition within the PDMS/glass microchannels through intermolecular interactions with the glass walls, hindering not only the process reproducibility but also the final biological application of the SCL products. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.056DOI Listing
March 2019
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Immunoreactivity changes of human serum albumin and alpha-1-microglobulin induced by their interaction with dendrimers.

Colloids Surf B Biointerfaces 2019 Apr 4;179:226-232. Epub 2019 Apr 4.

Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland. Electronic address:

Dendrimers are hyperbranched polymers for delivery of therapeutic genetic material to cancer cells. The fine tuning chemical modifications of dendrimers allow for the modification of the composition. The architecture and the properties of dendrimers are key factors to improve their in vitro and in vivo properties such as biocompatibility with cells and tissues and their pharmacokinetic/pharmacodynamic behavior. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.065DOI Listing
April 2019
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ROS-responsive targeting micelles for optical imaging-guided chemo-phototherapy of cancer.

Colloids Surf B Biointerfaces 2019 Apr 3;179:218-225. Epub 2019 Apr 3.

Department of Hepatobiliary & Pancreatic Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, China. Electronic address:

The combination of chemotherapy and phototherapy gives rise to a boom in cancer therapy methodology. An all-in-one nanoplatform is of particular interest for increased safety and efficacy geared toward personalized precision medicine. However, low drug loading efficiency, random dispersion and distribution without visualization are widespread concerns. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.005DOI Listing

Biological properties of a bionic scaffold for esophageal tissue engineering research.

Colloids Surf B Biointerfaces 2019 Apr 2;179:208-217. Epub 2019 Apr 2.

Department of Otorhinolaryngology, Lihuili Hospital of Ningbo University, Ningbo 315211, China. Electronic address:

Polyurethane is a good matrix material with wide application prospects in tissue engineering because of its adjustable and mechanical properties. A novel biodegradable crosslinked poly(ester urethane) (CPU) with flexible poly(caprolactone) (PCL) and hydrophilic poly(ethylene glycol) (PEG) components has been synthesized using a ferric iron catalyst in our laboratory. In the present study, to promote the interaction between the CPU material and cells, the material was superficially modified by silk fibroin (SF) grafting using an aminolysis and glutaraldehyde crosslinking method to achieve a biocompatible material, CPU-SF. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.072DOI Listing
April 2019
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Surface lattice resonance of line array of poly (glycidyl methacrylate) with CdS quantum dots for label-free biosensing.

Colloids Surf B Biointerfaces 2019 Apr 2;179:199-207. Epub 2019 Apr 2.

Department of Materials Science and Engineering, National Taiwan University of Science and Technology, 43, Sec 4, Keelung Rd., Taipei, 106, Taiwan, ROC; Applied Research Center for Thin-Film Metallic Glass, National Taiwan University of Science and Technology, Taipei, 10607, Taiwan, ROC. Electronic address:

One dimensional plasmonic grating is a kind of resonant electromagnetic wave absorber with a characteristic wavelength. This study focusses on one-dimensional plasmonic grating consisting of poly (glycidyl methacrylate) (PGMA) brushes and CdS quantum dots (CdQDs) fabrication and PGMA chains grafted on a primary substrate in a line array continued by the immobilization of biotin-modified CdQDs. PGMA brush line array (PBLA) of plasmonic grating exhibited an absorptance at 441 nm while at the same time, CdQDs immobilized with PBLA showed characteristic absorbance at 396 nm. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.073DOI Listing
April 2019
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Encapsulated functionalized stereocomplex PLA particles: An effective system to support mucolytic enzymes.

Colloids Surf B Biointerfaces 2019 Apr 1;179:190-198. Epub 2019 Apr 1.

Department of Chemistry and Industrial Chemistry, University of Genoa, Via Dodecaneso 31, 16146, Genoa, Italy. Electronic address:

In this work, the preparation of a novel enzyme carrier based on a polymer multicomponent system was assessed. Indeed, the design of the above system considered several issues that are the need of applying a biodegradable polymer carrier, characterized by a nanometric dimension, thus suitable to diffuse into the dense mucus structure, with functionalities capable of interacting/reacting with enzymes but resistant to enzymatic degradation. The particles were prepared from solutions containing equimolar amount of high-molecular-weight poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA) and by applying the nanoprecipitation method. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.071DOI Listing
April 2019
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Role of hydrophobicity in tuning the intracellular uptake of dendron-based fluorophores for in vitro metal ion sensing.

Colloids Surf B Biointerfaces 2019 Mar 28;179:180-189. Epub 2019 Mar 28.

Department of Chemistry, Indian Institute of Technology Madras (IIT M), Chennai, India. Electronic address:

Fluorophores are used for sensing biologically relevant ions, toxic metals or pathogenic markers. However, the mode of entry of such fluorophores into the cell greatly depends on their size, shape, surface charge, functional groups, and hydrophobicity. In particular, the influence of hydrophobicity on the intracellular uptake of fluorophores is poorly investigated. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.062DOI Listing
March 2019
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Enhanced visible-light-driven photocatalytic disinfection using AgBr-modified g-CN composite and its mechanism.

Colloids Surf B Biointerfaces 2019 Apr 2;179:170-179. Epub 2019 Apr 2.

State Key Joint Laboratory of Environment Simulation and Pollution Control, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Haidian District, Beijing 100085, PR China.

In this study, novel AgBr-modified g-CN (AgBr/g-CN) photocatalysts were prepared by an adsorption-deposition method and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Brunauer-Emmett-Teller (BET), and ultraviolet-visible spectroscopy (UV-vis). Furthermore, the photocatalytic disinfection performance on Escherichia coli (ATCC 15597) was investigated. The as-prepared photocatalysts exhibited well crystalline structures and morphologies with CN and exhibited a stronger bacterial inactivation than that of pristine g-CN. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.074DOI Listing

One step bulk modification of poly(L-lactic acid) composites with functional additives to improve mechanical and biological properties for cardiovascular implant applications.

Colloids Surf B Biointerfaces 2019 Mar 29;179:161-169. Epub 2019 Mar 29.

College of Life Sciences Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea. Electronic address:

Poly(L-lactic acid) (PLLA) has been widely used as a promising biomaterial in biomedical applications due to its biodegradability and high mechanical strength. However, because of the inherent brittleness, low impact resistance, and weak thermal stability of PLLA, the modification process is usually required to utilize it for biomedical devices. Furthermore, acidic byproducts resulting from the hydrolysis of PLLA after implantation reduce the pH of the surrounding environment and cause inflammatory responses in the implanted area, leading to the failure of their clinical applications. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.067DOI Listing
March 2019
3 Reads

Study of target spacing of thermo-sensitive carrier on the activity recovery of immobilized penicillin G acylase.

Colloids Surf B Biointerfaces 2019 Apr 1;179:153-160. Epub 2019 Apr 1.

Department of Physics and Engineering, Frostburg State University, Maryland, 21532, United States. Electronic address:

The immobilized penicillin G acylase (PGA) is an important industrial catalyst, the activity recovery rate of it directly affects enterprise efficiency. How to improve the enzyme activity recovery rate has been a research focus in this field. Based on the above problems, this work further improved the activity recovery rate by adjusting the target spacing for the first time. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.064DOI Listing
April 2019
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4.152 Impact Factor

In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice.

Colloids Surf B Biointerfaces 2019 Mar 28;179:143-152. Epub 2019 Mar 28.

Institute of Macromolecular Chemistry AS CR, Heyrovsky Sq. 1888/2, 162 06, Prague 6, Czech Republic.

The imaging of healthy tissues and solid tumors benefits from the application of nanoparticle probes with altered pharmacokinetics, not available to low molecular weight compounds. However, the distribution and accumulation of nanoprobes in vivo typically take at least tens of hours to be efficient. For nanoprobes bearing a radioactive label, this is contradictory to the requirement of minimizing the radiation dose for patients by using as-short-as-feasible half-life radionuclides in diagnostics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193020
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.057DOI Listing
March 2019
4 Reads

Production of 3D printed polylactide scaffolds with surface grafted hydrogel coatings.

Colloids Surf B Biointerfaces 2019 Apr 1;179:136-142. Epub 2019 Apr 1.

Warsaw University of Technology, Faculty of Chemical and Process Engineering, Department of Biotechnology and Bioprocess Engineering, Waryńskiego 1, 00-645 Warsaw, Poland; Centre for Advanced Materials and Technologies CEZAMAT, Warsaw University of Technology, Poleczki 19, 02-822 Warsaw, Poland. Electronic address:

The aim of this work was to elaborate the 3D printed polylactide (PLA) polymeric scaffolds and, subsequently, study the possibility of coating thereof with a biomedical polyvinylpyrrolidone (PVP) hydrogel through the previously patented protocol. Such materials have a potential to be applied in biomedical engineering, e.g. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193021
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.069DOI Listing
April 2019
5 Reads

Cationic poly(cyclodextrin)/alginate nanocapsules: From design to application as efficient delivery vehicle of 4-hydroxy tamoxifen to podocyte in vitro.

Colloids Surf B Biointerfaces 2019 Mar 28;179:128-135. Epub 2019 Mar 28.

Université Paris Est, ICMPE (UMR 7182), CNRS, UPEC, F-94320 Thiais, France. Electronic address:

Most of the drug molecules are partially insoluble in aqueous solution and then may accumulate in fat tissues hampering efficient therapy. Innovative drug delivery strategies have emerged in industry or academia over the last decades, however preserving the activity of the encapsulated drug, having high drug loading capacity and controlling drug release kinetics, are still challenging. In this context, we explored the preparation of new nanocarriers, namely nanocapsules, via a templating method, and using polysaccharides exhibiting biological functions. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.060DOI Listing
March 2019
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Layer-by-layer coated porous 3D printed hydroxyapatite composite scaffolds for controlled drug delivery.

Colloids Surf B Biointerfaces 2019 Mar 28;179:121-127. Epub 2019 Mar 28.

Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, 430074, China; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. Electronic address:

Interconnected porous scaffolds are widely used in the applications of tissue repair and regeneration. Sustained local delivery of drugs and growth factors around the implanted scaffolds could accelerate the growth of cells and contribute to the regeneration of damaged tissues. In this study, porous hydroxyapatite composite scaffolds were prepared through 3D bio-printing for bone tissue engineering and were subsequently coated with chitosan and sodium hyaluronate by layer-by-layer (LBL) deposition. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193021
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.063DOI Listing
March 2019
6 Reads

Green synthesis of Pluronic stabilized reduced graphene oxide: Chemical and biological characterization.

Colloids Surf B Biointerfaces 2019 Mar 25;179:94-106. Epub 2019 Mar 25.

Toxicology Division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram 695 012, Kerala, India. Electronic address:

The wonder material graphene has numerous potential applications in nanoelectronics, biomedicine, storage devices, etc. Synthesis of graphene is highly challenging due to the toxic chemicals used and its low yield. In the present study, a facile green route for synthesis of reduced graphene oxide (rGO) was carried out using ascorbic acid as reducing agent. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.043DOI Listing
March 2019
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A method based on amino-modified magnetic nanoparticles to extract DNA for PCR-based analysis.

Colloids Surf B Biointerfaces 2019 Mar 6;179:87-93. Epub 2019 Mar 6.

Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, Shanghai Academy of Agricultural Sciences, Shanghai, 201403, China. Electronic address:

DNA extraction using magnetic particles (MPs) is a simple and rapid process. MPs directly combine with DNA, thereby facilitating removal of impurities in complex samples by magnetic attraction. Amino-modified magnetic nanoparticles (AMNPs) have been described as poor substrates for DNA extraction because it was difficult to desorb DNA from the AMNPs for downstream assays. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09277765193014
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http://dx.doi.org/10.1016/j.colsurfb.2019.03.005DOI Listing
March 2019
3 Reads

In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy.

Colloids Surf B Biointerfaces 2019 Mar 16;179:77-86. Epub 2019 Mar 16.

Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China. Electronic address:

Copper (Cu) has a good antibacterial effect and micro-arc oxidation (MAO) coating has good corrosion resistance for magnesium (Mg) alloys. If they are combined together, the coated Mg alloy is expected to have both good corrosion resistance and antibacterial effect. In this work, the degradation, antibacterial property and cytotoxicity of a Cu-containing MAO coating on an extruded Mg-2Zn-1Gd-0. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2019.03.023DOI Listing
March 2019
4.152 Impact Factor