131,902 results match your criteria Colloids and surfaces. B Biointerfaces[Journal]


Self-faceting of emulsion droplets as a route to solid icosahedra and other polyhedra.

J Colloid Interface Sci 2018 Dec 2;538:541-545. Epub 2018 Dec 2.

Department of Physics, Bar-Ilan University, Ramat-Gan 5290002, Israel; Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 5290002, Israel. Electronic address:

Hypothesis: Temperature-controlled self-faceting of liquid droplets has been recently discovered in surfactant-stabilized alkane-in-water emulsions. We hypothesize that similar self-faceting may occur in emulsion droplets of UV-polymerizable linear hydrocarbons. We further hypothesize that the faceted droplet shapes can be fixed by UV-initiated polymerization, thus providing a new route towards the production of solid polyhedra. Read More

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December 2018

Prolonging food shelf-life by dual actives release from multi-layered polymer particles.

Colloids Surf B Biointerfaces 2018 Dec 4;175:281-290. Epub 2018 Dec 4.

Department of Materials Science and Engineering, Indian Institute of Technology, Delhi, 110016, India. Electronic address:

Biodegradable polymer based 'controlled release packaging' technology has ability to release packaging actives in controlled manner to prolong the food shelf-life. Currently available systems are not sufficiently capable of releasing multiple actives in sustainable fashion. Hence, the purpose of this study was to develop dual actives (antioxidant and antibacterial) loaded multilayered microparticles in one step and to release them at rates suitable for long-term inhibition of bacterial growth as well as lipid oxidation in food. Read More

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December 2018

Ln(III) chelates-functionalized carbon quantum dots: Synthesis, optical studies and multimodal bioimaging applications.

Colloids Surf B Biointerfaces 2018 Nov 22;175:272-280. Epub 2018 Nov 22.

State Key Laboratory of Environmental and Biological Analysis and Department of Chemistry, Hong Kong Baptist University, Waterloo Road, Hong Kong, China. Electronic address:

The carbon quantum dots termined with amine groups (CQDs-NH) were synthesized in one-pot hydrothermal method with citric acid as carbon source and branched polyethylenimine (BPEI) as passive agent, which was then covalently linked to 1, 4, 7, 10-tetraazacyclononane (DOTA) framework to yield CQDs-DOTA. The CQDs-DOTA provide excellent ligand scaffolds for the chelation of lanthanide ions, yielding the related complexes CQDs-DOTA-Ln (Ln = Eu, Tb, Yb and Gd). The successful preparation of CQDs-DOTA-Ln was validated by TEM, XRD, XPS, and FT-IR spectroscopy. Read More

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November 2018

Lecithin doped electrospun poly(lactic acid)-thermoplastic polyurethane fibers for hepatocyte viability improvement.

Colloids Surf B Biointerfaces 2018 Sep 28;175:264-271. Epub 2018 Sep 28.

College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, China. Electronic address:

The development of hepatocyte cultures in vitro holds great significance in the study of bioartificial liver support systems. Electrospun fiber cultures have received widespread attention as an effective method to culture hepatocytes in vitro. Polylactic acid (PLA) -a synthetic polymer with high biocompatibility and biodegradability- is widely used to fabricate electrospun fibers in the biomedical field. Read More

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September 2018

Organization of Particle Islands Via Light-Powered Fluid Pumping.

Angew Chem Int Ed Engl 2018 Dec 13. Epub 2018 Dec 13.

Pennsylvania State University, Department of Chemistry, 104 Chemistry Building, 16802, University Park, UNITED STATES.

The field of active matter holds promise for applications in particle assembly, cargo and drug delivery, and sensing. In pursuit of these capabilities, researchers have produced a suite of nanomotors, fluid pumps, and particle assembly strategies. Although promising, there are many challenges, especially for mechanisms that rely on chemical propulsion. Read More

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December 2018

Smart complex fluids based on two-antennary oligoglycines.

ChemSusChem 2018 Dec 12. Epub 2018 Dec 12.

BULGARIA.

Antennary oligoglycines are synthetic products, obtained by preliminary molecular design. Equal-length antennae are built of glycine residues jointed by C-end to oligoamine branching core with amine group at the N-terminus exposed outside. Results from a systematic research on properties of aqueous solutions containing two-antennary oligoglycine with four glycine portions are reported here. Read More

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December 2018

Vibrational Modes and Dynamic Heterogeneity in a Near-Equilibrium 2D Glass of Colloidal Kites.

Phys Rev Lett 2018 Nov;121(22):228003

Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People's Republic of China.

Using video microscopy and particle-tracking techniques developed for dense Brownian systems of polygons, we study the structure-dynamics relationship in a near-equilibrium 2D glass consisting of anisotropic Penrose kite-shaped colloids. Detailed vibrational properties of kite glasses, both translational and rotational, are obtained using covariance matrix techniques. Different from other colloidal glasses of spheres and ellipsoids, the vibrational modes of kite glasses at low frequencies show a strong translational character with spatially localized rotational modes and extended translational modes. Read More

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November 2018

Supramolecular Modification of ABC Triblock Terpolymers in Confinement Assembly.

Nanomaterials (Basel) 2018 Dec 10;8(12). Epub 2018 Dec 10.

Physical Chemistry, University of Duisburg-Essen, 47057 Duisburg, Germany.

The self-assembly of AB diblock copolymers in three-dimensional (3D) soft confinement of nanoemulsions has recently become an attractive bottom up route to prepare colloids with controlled inner morphologies. In that regard, ABC triblock terpolymers show a more complex morphological behavior and could thus give access to extensive libraries of multicompartment microparticles. However, knowledge about their self-assembly in confinement is very limited thus far. Read More

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December 2018

Purification and characterization of a biosurfactant produced by Bacillus subtilis in cashew apple juice and its application in the remediation of oil-contaminated soil.

Colloids Surf B Biointerfaces 2018 Nov 27;175:256-263. Epub 2018 Nov 27.

Department of Chemical Engineering, Universidade Federal do Ceará, Brazil.

The ability of some microorganisms to use clarified cashew apple juice as carbon and energy source for biosurfactant production was assessed under strict controlled conditions. Twelve strains of Bacillus were isolated and evaluated regarding their biosurfactant production capabilities. The biosurfactant obtained with these selected strains showed the capacity of decreasing the surface tension of water from 72. Read More

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November 2018
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Spontaneous assembly of colloidal vesicles driven by active swimmers.

Authors:
Luca Angelani

J Phys Condens Matter 2018 Nov 30. Epub 2018 Nov 30.

CNR, Rome, ITALY.

We explore the self-assembly process of colloidal structures immersed in active baths. By considering low-valence particles we numerically investigate the irreversible aggregation dynamics originated by the presence of run-and-tumble swimmers. We observe the formation of long closed chains -- vesicles -- densely filled by active swimmers. Read More

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November 2018

Crystalloid coloading vs. colloid coloading in elective Caesarean section: postspinal hypotension and vasopressor consumption, a prospective, observational clinical trial.

J Anesth 2018 Dec 6. Epub 2018 Dec 6.

Department of Anaesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.

Background: Maternal hypotension is a common side effect of spinal anaesthesia for Caesarean section. The combination of colloid coloading and vasopressors was considered our standard for its prevention and treatment. As the safety of hydroxyethyl starch is under debate, we replaced colloid with crystalloid coloading. Read More

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December 2018

Self-assembled CpG oligodeoxynucleotides conjugated hollow gold nanospheres to enhance cancer-associated immunostimulation.

Colloids Surf B Biointerfaces 2018 Dec 3;175:248-255. Epub 2018 Dec 3.

Key Laboratory of Coal Conversion & New Carbon Materials of Hubei Province, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, PR China. Electronic address:

To realize efficiently cellular uptake and enhance the immunostimulation, thiolated cytosine-phosphate-guanine (CpG) oligodeoxynucleotides (ODNs) were self-assembled on hollow gold nanospheres (HGNs) to form CpG-HGNs. The cellular uptake of CpG-HGNs in immune cells was studied in RAW 264.7 cells. Read More

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December 2018

Photothermally controlled drug release system with high dose loading for synergistic chemo-photothermal therapy of multidrug resistance cancer.

Colloids Surf B Biointerfaces 2018 Dec 5;175:239-247. Epub 2018 Dec 5.

Laboratory of Environmental Sciences and Technology, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences, Urumqi, Xinjiang 830011, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China. Electronic address:

Chemotherapy is an important first-line strategy for tumor therapy in cancer treatment, but multidrug resistance (MDR) is a major problem that reduces the efficacy of chemotherapeutics. Herein, we report a novel photothermally controlled intelligent drug release system (AuNP@mSiO-DOX-FA) with a large amount of drugs loading for synergistic chemo-photothermal therapy of MDR in breast cancer. The nanoplatform utilized gold nanoparticles as a hyperthermia core, and large-mesoporous silica as a shell for doxorubicin (DOX) loading. Read More

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December 2018

Crystalloids vs. colloids for fluid resuscitation in the Intensive Care Unit: A systematic review and meta-analysis.

J Crit Care 2018 Nov 30;50:144-154. Epub 2018 Nov 30.

Meridian HealthComms, Plumley Moor Road, Plumley, UK. Electronic address:

Purpose: Guidelines recommend crystalloids for fluid resuscitation in sepsis/shock and switching to albumin in cases where crystalloids are insufficient. We evaluated hemodynamic response to crystalloids/colloids in critically ill adults.

Materials And Methods: The primary research question was: "Are crystalloids sufficient for volume replacement in severe indications (intensive care unit [ICU]/critical illness)?" Randomized, controlled trials (RCTs) were identified using PubMed and EMBASE, and screened against predefined inclusion/exclusion criteria. Read More

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November 2018

New Insights into Black Carbon Nanoparticle-induced Dispersibility of Goethite Colloids and Configuration-dependent Sorption for Phenanthrene.

Environ Sci Technol 2018 Dec 12. Epub 2018 Dec 12.

Black carbon nanoparticles (nano-BC) are one of the most active components in pyrogenic carbonaceous matter and involve in many biogeochemical processes. This study investigated heteroaggregation of nano-BC with goethite (a model of natural mineral colloids) and the configuration effect of heteroaggregates on phenanthrene (PHE) sorption. Nano-BC could significantly enhance the dispersion of goethite via heteroaggregation when its concentration was higher than the critical concentration (Cc). Read More

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December 2018

Directional freezing of binary colloidal suspensions: a model for size fractionation of graphene oxide.

Soft Matter 2018 Dec 12. Epub 2018 Dec 12.

Center of Soft Matter Physics and Its Applications, Beihang University, Beijing 100191, China.

The performance of graphene oxide (GO)-based materials strongly depends on the lateral size and size distribution of GO nanosheets. Various methods are employed to prepare GO nanosheets with a narrow size distribution. One promising method was proposed recently, directional freezing of a GO aqueous dispersion at a controlled growth rate of the freezing front. Read More

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December 2018

A High-Throughput Magnetic Nanoparticle-Based Semi-Automated Antibody Phage Display Biopanning.

Methods Mol Biol 2019 ;1904:377-400

Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia.

Panning is a common process used for antibody selection from phage antibody libraries. There are several methods developed for a similar purpose, namely streptavidin mass spectrometry immunoassay (MSIA™) Disposable Automation Research Tips, magnetic beads, polystyrene immunotubes, and microtiter plate. The advantage of using a magnetic particle processor system is the ability to carry out phage display panning against multiple target antigens simultaneously in parallel. Read More

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January 2019
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A novel MUC1 aptamer-modified PLGA-epirubicin-PβAE-antimir-21 nanocomplex platform for targeted co-delivery of anticancer agents in vitro and in vivo.

Colloids Surf B Biointerfaces 2018 Dec 4;175:231-238. Epub 2018 Dec 4.

Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Conventional chemotherapy suffers from several drawbacks, including toxic side effects together with the development of resistance to the chemical agents. Therefore, exploring alternative therapeutic approaches as well as developing targeted delivery systems are in demand. Oligonucleotide-based therapy has emerged as a promising and alternative procedure for treating malignancies involving gene-related diseases. Read More

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December 2018

Synthesizing, characterizing, and toxicity evaluating of Phycocyanin-ZnO nanorod composites: A back to nature approaches.

Colloids Surf B Biointerfaces 2018 Dec 4;175:221-230. Epub 2018 Dec 4.

Division of Industrial & Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), P.O. Box 14155-6343, Tehran, Iran. Electronic address:

C-Phycocyanin pigment was purified from a native cyanobacterial strain using a novel consecutive multi-step procedure and utilized for the first time for the green synthesis of phycocyanin-zinc oxide nanorods (PHY-ZnO NRs) by a simple, low-cost and eco-friendly approach. The PHY-ZnO NRs were characterized using UV-vis spectroscopy, X-ray diffraction (XRD), zeta potential measurement, FTIR, SEM, TEM, differential scanning calorimetry (DSC), thermogravimetric (TGA), and EDX spectroscopy analysis. The UV-vis spectra showed an absorption band at 364 nm which is characteristic of ZnO nanoparticles (ZnONPs). Read More

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December 2018

Effects of crystalloids and colloids on microcirculation, central venous oxygen saturation, and central venous-to-arterial carbon dioxide gap in a rabbit model of hemorrhagic shock.

J Anesth 2018 Dec 10. Epub 2018 Dec 10.

Department of Cardiovascular Surgery, Tokyo Women's Medical University, 8-1, Kawadacho Shinjuku-ku, Tokyo, 162-8666, Japan.

Objective: The effects of hydroxyethyl starch (HES) on microcirculation, central venous oxygen saturation (ScvO), and the central venous-to-arterial carbon dioxide gap (dCO) are studied in a rabbit model of hemorrhagic shock for elucidating the advantages and drawbacks of resuscitation with HES compared with crystalloids.

Methods: An ear chamber and sublingual mucosa were used to examine blood vessels by intravital microscopy. Hemorrhagic shock was induced by removing nearly half of the blood volume. Read More

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December 2018

Regulation of phosphorus bioavailability by iron nanoparticles in a monomictic lake.

Sci Rep 2018 Dec 10;8(1):17736. Epub 2018 Dec 10.

Australian Rivers Institute, Griffith University, Griffith, Australia.

Dissolved reactive phosphorous (DRP) in lake systems is conventionally considered to predominate over other dissolved P species, however, this view neglects an important set of interactions that occurs between P and reactive iron hydroxide surfaces. This study addresses the coupling of P with dispersed iron nanoparticles in lakes, an interaction that may fundamentally alter the bioavailability of P to phytoplankton. We used diffusive gradients in thin films (DGT) and ultrafiltration to study Fe-P coupling in the water column of a monomictic lake over a hydrological year. Read More

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December 2018

Improving vaccines against using synthetic glycans.

Proc Natl Acad Sci U S A 2018 Dec 7. Epub 2018 Dec 7.

Department of Biomolecular Systems, Max-Planck Institute of Colloids and Interfaces, 14476 Potsdam, Germany;

remains a deadly disease in small children and the elderly even though conjugate and polysaccharide vaccines based on isolated capsular polysaccharides (CPS) are successful. The most common serotypes that cause infection are used in vaccines around the world, but differences in geographic and demographic serotype distribution compromises protection by leading vaccines. The medicinal chemistry approach to glycoconjugate vaccine development has helped to improve the stability and immunogenicity of synthetic vaccine candidates for several serotypes leading to the induction of higher levels of specific protective antibodies. Read More

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December 2018
2 Reads

DNA nanostructures doped with lanthanide ions for highly sensitive UV photodetectors.

Colloids Surf B Biointerfaces 2018 Dec 1;175:212-220. Epub 2018 Dec 1.

Sungkyunkwan Advanced Institute of Nanotechnology (SAINT) and Department of Physics, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address:

Deoxyribonucleic acid (DNA) and lanthanide ions (Ln) exhibit exceptional optical properties that are applicable to the development of nanoscale devices and sensors. Although DNA nanostructures and Ln ions have been investigated for use in the current state of technology for more than a few decades, researchers have yet to develop DNA and Ln based ultra-violet (UV) photodetectors. Here, we fabricate Ln (such as holmium (Ho), praseodymium (Pr), and ytterbium (Yb))‒doped double crossover (DX)‒DNA lattices through substrate-assisted growth and salmon DNA (SDNA) thin films via a simple drop-casting method on oxygen (O) plasma-treated substrates for high performance UV photodetectors. Read More

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December 2018

Designing of fatty acid-surfactant conjugate based nanomicelles of morin hydrate for simultaneously enhancing anticancer activity and oral bioavailability.

Colloids Surf B Biointerfaces 2018 Nov 28;175:202-211. Epub 2018 Nov 28.

School of Nano Sciences, Central University of Gujarat, Gandhinagar, 382030, Gujarat, India. Electronic address:

Morin hydrate (MH) is a naturally occurring polyphenolic flavonol compound. It has been recently investigated for its many biological activities such as anti-inflammatory, anticancer, antioxidant, antiarthritic, antifertility, antiplasmodic and anticancer. Though these outcomes are very promising, its low aqueous solubility and oral bioavailability restrict its clinical uses. Read More

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November 2018

Quantitative evaluation of different fractions of extracellular polymeric substances derived from Paenibacillus mucilaginosus against the toxicity of gold ions.

Colloids Surf B Biointerfaces 2018 Nov 28;175:195-201. Epub 2018 Nov 28.

College of Life Sciences, Nanjing Normal University, No.1, WenYuan Road, QiXia District, Nanjing, Jiangsu Province, 210023, China. Electronic address:

The reductive detoxification of microbes is of significant importance as toxic high oxidation-state metals are ubiquitous in the environment. As a protective interface, extracellular polymeric substances (EPS) are known to play an important role in reducing the toxicity, the relative contribution of different EPS fractions in the process of microbial reductive detoxification remains not to be understood. In this study, we used toxic gold ions (Au) and EPS fractions from Paenibacillus mucilaginosus as an example to quantitatively assess the relative contribution of different EPS fractions in the process of the reductive detoxification. Read More

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November 2018

Insight into the mechanism and factors on encapsulating basic model protein, lysozyme, into heparin doped CaCO.

Colloids Surf B Biointerfaces 2018 Nov 29;175:184-194. Epub 2018 Nov 29.

School of Ophthalmology and Optometry, Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang Province, 325035, PR China; Wenzhou Institute of Biomaterials and Engineering, CNITECH, CAS, Wenzhou, Zhejiang Province, 325001, PR China; Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province, Wenzhou Institute of Biomaterials and Engineering, CAS, Wenzhou, Zhejiang Province, 325001, PR China. Electronic address:

Porous CaCO microparticles are considered as one of the most popular and effective carriers for protein loading. Most of current studies have centered on elucidating particle formation and enhancing the protein loading efficiency, very few reports on the kinetics, driving forces and factors on protein loading process. Here, we took lysozyme as the basic model protein to investigate the kinetics, driving forces on protein loading and factors controlling loading efficiency into porous Hep/CaCO microparticles by various techniques (protein quantification assay, QCM-D, SEM, BET, Zeta sizer, TGA, CLSM, CD spectrum, bioactive assay). Read More

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November 2018

A carefully designed nanoplatform based on multi walled carbon nanotube wrapped with aptamers.

Colloids Surf B Biointerfaces 2018 Nov 27;175:175-183. Epub 2018 Nov 27.

Centro de Desenvolvimento da Tecnologia Nuclear, 31270-901 Belo Horizonte, MG, Brazil. Electronic address:

The interaction between carbon nanotubes (CNTs) and biological molecules of diagnostic and therapeutic interest, as well as the internalization of the CNTs-biomolecules complexes in different types of cell, has been extensively studied due to the potential use of these nanocomplexes as multifunctional nanoplatforms in a great variety of biomedical applications. The effective use of these nanobiotechnologies requires broad multidisciplinary studies of biocompatibility, regarding, for example, the in vitro and in vivo nanotoxicological assays, the capacity to target specific cells and the evaluation of their biomedical potential. However, the first step to be reached is the careful obtainment of the nanoplatform and the understanding of the actual surface composition and structural integrity of the complex system. Read More

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November 2018
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Clotrimazole multiple W/O/W emulsion as anticandidal agent: Characterization and evaluation on skin and mucosae.

Colloids Surf B Biointerfaces 2018 Nov 29;175:166-174. Epub 2018 Nov 29.

Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Granada, University Campus of Cartuja, 18071 Granada, Spain; Nanoscience and Nanotechnology Institute (IN2UB), University of Barcelona, 645 Diagonal Ave., 08028 Barcelona, Spain. Electronic address:

Clotrimazole (CLT) was formulated in a multiple W/O/W emulsion (ME) with the aim of evaluating its potential as topical anticandidal agent and comparing with marketed products. A previously evaluated CLT-ME was selected and physicochemically characterized. The in vitro release behavior and the ex vivo permeation profiles were assessed using Franz diffusion cells using three different types of biological membranes: human skin and porcine buccal, sublingual and vaginal mucosae. Read More

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November 2018

Study on MgSr(PO) bioceramics as potential bone grafts.

Colloids Surf B Biointerfaces 2018 Nov 30;175:158-165. Epub 2018 Nov 30.

School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, People's Republic of China. Electronic address:

Magnesium (Mg) and strontium (Sr), which are essential nutrient elements in the natural bone, positively affect the osteogenic activity even in wide ranges of ion concentrations. However, it remains unknown whether magnesium-strontium phosphates [MgSr(PO)] are potential bone grafts for accelerating bone regeneration. Herein, a serial of MgSr(PO), including Mg(PO), MgSr(PO), MgSr(PO), MgSr(PO) and Sr(PO), were synthesized using a solid-state reaction approach. Read More

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November 2018

Topical gel of Metformin solid lipid nanoparticles: A hopeful promise as a dermal delivery system.

Colloids Surf B Biointerfaces 2018 Nov 28;175:150-157. Epub 2018 Nov 28.

Pharmaceutics Research Laboratory, School of Life Sciences, University of Sussex, Brighton, BN1 9QJ, UK; Drug Applied Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:

The aim of the present study was to enhance the skin delivery of metformin by making solid lipid nanoparticles containing metformin using the ultra-sonication method. To achieve the optimum skin delivery for metformin, the effects of the ratio of two surfactants (Tween:Span) on nanoparticles properties and their performance were investigated. Photon correlation spectroscopy, scanning electron microscopy (SEM), Powder X-ray Diffractometer (PXRD), Fourier transform infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC) were used to characterize the solid state of metformin in solid lipid nanoparticles. Read More

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November 2018

Enhanced oral bioavailability and brain uptake of Darunavir using lipid nanoemulsion formulation.

Colloids Surf B Biointerfaces 2018 Nov 22;175:143-149. Epub 2018 Nov 22.

Faculty of Pharmacy, The M.S. University of Baroda, Vadodara, 390002, Gujarat, India. Electronic address:

The present work aimed to formulate Darunavir loaded lipid nanoemulsion to increase its oral bioavailability and enhance brain uptake. Various batches of lipid nanoemulsion of Darunavir were prepared by high pressure homogenization using soya bean oil, egg lecithin and Tween 80. The optimized batch DNE-3 had globule size of 109. Read More

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November 2018

Alcohol dehydrogenase on inorganic powders: Zeta potential and particle agglomeration as main factors determining activity during immobilization.

Colloids Surf B Biointerfaces 2018 Nov 29;175:136-142. Epub 2018 Nov 29.

Technical University of Denmark, DTU Chemical Engineering, Søltofts Plads, Building 229, 2800 Kgs, Lyngby, Denmark. Electronic address:

Alcohol dehydrogenase from Saccharomyces cerevisiae was immobilized on different inorganic support materials, i.e. powders of AlO, SiC, TiO and YSZ-8, by covalent bonding and physical adsorption. Read More

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November 2018

Co-delivery of paclitaxel and doxorubicin using mixed micelles based on the redox sensitive prodrugs.

Colloids Surf B Biointerfaces 2018 Dec 1;175:126-135. Epub 2018 Dec 1.

Department of Pharmaceutics, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong Province, 250012, China. Electronic address:

A strategy of preparing mixed micelles containing both DOX prodrug and PTX prodrug was developed, i.e., synthesizing a DOX conjugate and a PTX conjugate started with the same biocompatible amphiphilic copolymer, TPGS and DTDPA, a linker containing disulfide bond. Read More

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December 2018

Preparation and characterization of metallomicelles of Ru(II). Cytotoxic activity and use as vector.

Colloids Surf B Biointerfaces 2018 Nov 29;175:116-125. Epub 2018 Nov 29.

Departamento de Química Física, Facultad de Química, Universidad de Sevilla, c/ Prof. García González nº 1, Seville, 41012, Spain. Electronic address:

The use of nanovectors in several medicinal treatments has reached a great importance in the last decade. Some drugs need to be protected to increase their lifetimes in the blood flow, to avoid degradation, to be delivered into target cells or to decrease their side effects. The goal of this work was to design and prepare nanovectors formed by novel surfactants derived from the [Ru(bpy)] complex. Read More

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November 2018

Glycyrrhetinic acid-conjugated polymeric prodrug micelles co-delivered with doxorubicin as combination therapy treatment for liver cancer.

Colloids Surf B Biointerfaces 2018 Nov 30;175:106-115. Epub 2018 Nov 30.

Department of Pharmaceutics, School of Pharmacy, Ningxia Medical University, No. 1160, Shengli Street, Yinchuan, 750004, China; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, 750004, China. Electronic address:

Significant synergy of doxorubicin (DOX) and glycyrrhizic acid (GA) in inhibiting the proliferation of cancer cells was demonstrated in the human hepatocellular carcinoma cell line, HepG2. A novel polymeric prodrug micellar carrier based on polyethylene glycol-derivatized GA (PEG-Fmoc-GA), was developed for co-delivery of DOX as a combined anti-cancer treatment. The PEG-Fmoc-GA polymeric prodrug micelles achieved a more effective synergistic action on cell proliferation inhibition and apoptosis induction, when co-delivered with DOX, which can be attributed to the dual effect of the cleaved GA and loaded DOX. Read More

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November 2018

NaYF@Yb,Ho,Au/GO-nanohybrid materials for SERS applications-Pb(II) detection and prediction.

Colloids Surf B Biointerfaces 2018 Nov 19;174:598-606. Epub 2018 Nov 19.

Department of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu - 212013, PR China.

Nowadays, nano hybrid materials (NHMs) with latent applications have been employed in different fields, particularly for sensor applications. Among NHMs, GO based - upconversion NHMs system is an emerging area for the rapid detection of different hazardous materials either as an aptamer based or free-labeled sensing techniques. For the detection of Pb(II) in water, NaYF@Yb,Ho,Au/GO-NaYF@Yb,Ho,Au NHMs system was developed. Read More

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November 2018

Remediation of cadmium, lead and zinc in contaminated soil with CETSA and MA/AA.

J Hazard Mater 2018 Dec 1;366:177-183. Epub 2018 Dec 1.

College of Environmental Sciences, Sichuan Agricultural University, Wenjiang, 611130, PR China.

Soil washing, which is used to remove heavy metals from soil, is dependent on suitable washing agents. However, there is still a lack of economical, environmentally friendly washing agents with high removal efficiency. In this study, three washing agents, carboxyalkylthiosuccinic acid (CETSA), copolymer of maleic and acrylic acid (MA/AA) and ethylenediamine tetra acetic acid (EDTA), were used to remove heavy metals from contaminated soil. Read More

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December 2018
5 Reads

A sensitive biosensing method for detecting of ultra-trace amounts of AFB1 based on "Aptamer/reduced graphene oxide" nano-bio interaction.

Colloids Surf B Biointerfaces 2018 Dec 1;175:98-105. Epub 2018 Dec 1.

Department of Chemistry, Payame Noor University (PNU), P.O. Box: 19395-4697, Tehran, Iran. Electronic address:

A simple, low-cost and sensitive label-free aptasensor assembled with assisting reduced graphene oxide nanosheets as the signal amplifier was fabricated and applied for detecting ultra-low levels of Aflatoxin B1(AFB1) through a nano-bio interaction system. The conditions of different modified glassy carbon electrodes as the base of aptasensor were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). The performance of the fabricated aptasensor was evaluated by FESEM, HRTEM and AFM images. Read More

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December 2018
2 Reads

Elaboration of a thermosensitive smart biomaterial: From synthesis to the ex vivo bioadhesion evaluation.

Colloids Surf B Biointerfaces 2018 Nov 30;175:91-97. Epub 2018 Nov 30.

CIRIMAT, Université de Toulouse 3 - Paul Sabatier, CNRS, Toulouse, France. Electronic address:

Alginate and chitosan are polysaccharides that are widely used in the biomedical field, especially as wound dressings. Controlled bioadhesion is an advanced functionality that offers the potential to reduce injuries due to the stripping-off of the biomaterial. Herein, we report the efficient grafting of poly-N(isopropylacryamide) (PNIPAM), a thermosensitive polymer that exhibits a lower critical solution temperature (LCST) at 32 °C on the alginate/chitosan polyelectrolyte complex (PEC) surface. Read More

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November 2018
3 Reads

Evaluation of hetero-multivalent lectin binding using a turbidity-based emulsion agglutination assay.

Colloids Surf B Biointerfaces 2018 Nov 28;175:84-90. Epub 2018 Nov 28.

Dept. of Chemical Engineering, Texas A&M University, College Station, TX, 77843, USA. Electronic address:

Lectin hetero-multivalency, binding to two or more different types of ligands, has been demonstrated to play a role in case of both LecA (a Pseudomonas aeruginosa adhesin) and Cholera Toxin subunit B (a Vibrio cholerae toxin). In order to screen the ligand candidates that involve in hetero-multivalent binding from large molecular libraries, we present a turbidity-based emulsion agglutination (TEA) assay that can be conducted in a high-throughput format using the standard laboratory instruments and reagents. The benefit of this assay is that it relies on the use of emulsions that can be formed using ultrasonication, minimizing the bottleneck of substrate surface functionalization. Read More

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November 2018
2 Reads

Chitosan microparticles embedded with multi-responsive poly(N-vinylcaprolactam-co-itaconic acid-co-ethylene-glycol dimethacrylate)-based hydrogel nanoparticles as a new carrier for delivery of hydrophobic drugs.

Colloids Surf B Biointerfaces 2018 Nov 22;175:73-83. Epub 2018 Nov 22.

Laboratory of Polymers, Department of Chemical Engineering, Engineering School of Lorena, University of São Paulo, EEL-USP, Estrada Municipal do Campinho, s/n, 12602-810, Lorena, SP, Brazil. Electronic address:

In this paper, chitosan was used as protective agent for dual temperature-/pH-sensitive poly(N-vinylcaprolactam-co-itaconic acid-co-ethylene- glycol dimethacrylate)- based hydrogel nanoparticles (poly(NVCL-co-IA-co-EGDMA)) aiming avoid their undesirable colloidal destabilization at different conditions of body human tissues. Thus, poly(NVCL-co-IA-co-EGDMA) was embedded into chitosan and a new solid dispersion was prepared via spray-drying and ketoprofen was used as carrier. Two different sizes of hydrogel nanoparticles (120. Read More

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November 2018
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A dual-sensitive mesoporous silica nanoparticle based drug carrier for cancer synergetic therapy.

Colloids Surf B Biointerfaces 2018 Nov 28;175:65-72. Epub 2018 Nov 28.

College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address:

A multifunctional envelope-type mesoporous silica nanoparticle (MSN) was delicately designed for subcellular co-delivery of drug and therapeutic peptide to tumor cells. Firstly, a kind of cell apoptosis peptide (KLAKLAK) (KLA) was anchored on surface of MSN via disulfide bond to obtain MSN-SS-KLA. Subsequently, anticancer drug doxorubicin hydrochloride (DOX) was loaded into the pores of MSN-SS-KLA. Read More

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November 2018
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Ligand density and linker length are critical factors for multivalent nanoparticle-receptor interactions.

ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.

Although there is a large number of studies available evaluating the therapeutic efficacy of targeted polymeric nanoparticles, little is known about the critical attributes that can further influence their uptake into target cells. In this study, varying cRGD ligand densities (0-100% surface functionalization) were combined with different PEG spacer lengths (2/3.5/5kDa) and the specific receptor binding of targeted core-shell structured PLGA/PLA-PEG nanoparticles was evaluated using αβ integrin overexpressing U87MG glioblastoma cells. Read More

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December 2018
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Colloidal FeIII, MnIII, CoIII and CuII hydroxides stabilized by starch as catalysts of water oxidation reaction with one electron oxidant Ru(bpy)33.

Chemphyschem 2018 Dec 6. Epub 2018 Dec 6.

Boreskov Institute of Catalysis RAS, pr. Lavrenteva 5, 630000, Novosibirsk, RUSSIAN FEDERATION.

Colloidal catalysts for water oxidation to dioxygen, which are stable on storage and under the reaction conditions, are synthesized based on CoIII, MnIII, FeIII and CuII hydroxides. Stabilization of the colloids with dextrated starch allows the process of hydroxide ageing to be stopped at the stage of the formation of primary nuclei (ca. 2-3 nm from TEM data). Read More

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December 2018
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Anaphylaxis to intravenous gelatin-based solutions: a case series examining clinical features and severity.

Anaesthesia 2018 Dec 5. Epub 2018 Dec 5.

Department of Anaesthesia and Peri-operative Medicine, Monash University, Melbourne, Vic., Australia.

The proportion of patients receiving intravenous gelatin-based colloids has increased in the last decade due to safety concerns about starch-based products. Recent research suggests hypersensitivity reactions to intravenous gelatin-based solutions occur at similar rates per administration as non-depolarising neuromuscular blocking agents such as rocuronium (6.2/100,000 administrations). Read More

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December 2018
3 Reads

Special features of monolayer characteristics of N-alkanoyl substituted threonine amphiphiles.

Phys Chem Chem Phys 2018 Dec 6. Epub 2018 Dec 6.

Max Planck Institute of Colloids and Interfaces, D-14424 Potsdam/Golm, Germany.

The monolayers of N-alkanoyl substituted threonine amphiphiles, similar to those of other N-alkanoyl-substituted amino acid amphiphiles, point to substantial differences in the main characteristics compared to usual amphiphilic monolayers. π-A measurements of the enantiomeric and racemic forms of N-alkanoyl-substituted threonine monolayers with C16 and C18 chain lengths reveal that, independent of the alkyl chain length, all compression curves are located above the corresponding decompression curves. A theoretical model developed for the kinetics of two-dimensional condensation of Langmuir monolayers can describe this behavior concluding the attachment of monomers to large aggregates. Read More

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December 2018
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Postoperative Visual Loss: A Report of One Patient With Unilateral Blindness After Orthognathic Surgery.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Oral and Maxillofacial Department, Roger Salengro Hospital, CHU Lille.

Introduction: Blindness after orthognathic surgery may be the result of the surgical procedure itself or the consequence of factors induced by general anesthesia. However, the exact mechanism between is not known. The purpose of this article is to present a case of a postoperative visual loss after orthognathic surgery under general anesthesia concluding with a brief literature review about this topic. Read More

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November 2018
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Maternal anaesthesia in open and fetoscopic surgery of foetal open spinal neural tube defects: A 6-year observational study.

Eur J Anaesthesiol 2018 Nov 30. Epub 2018 Nov 30.

From the Anaesthesiology and Intensive Care Department (SM, IG, MP, RP, DB, MdN), Maternal-Fetal Medicine Department (NM, SA, EC), Paediatric Surgery Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain (CG, JAM, ML).

Background: Prenatal myelomeningocele repair by open surgery can improve the neurological prognosis of children with this condition. A shift towards a fetoscopic approach seems to reduce maternal risks and improve obstetric outcomes.

Objective: The aim of this study was to report on the anaesthetic management of women undergoing prenatal open or fetoscopic surgery for neural tube defects. Read More

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November 2018
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Kinetically Controlled Self-Assembly of Block Copolymers into Segmented Worm-Like Micelles in Microfluidic Chips.

Langmuir 2018 Dec 3. Epub 2018 Dec 3.

Kinetically controlled self-assembly of block copolymers (BCPs) in solution is an efficient route to fabricate complex hierarchical colloids which are of great importance for nanoencapsulation, microreactors, and biomimics. Herein, segmented worm-like micelles (SWMs) with controllable size are generated by self-assembly of polystyrene-block-poly(4-vinyl pyridine) (PS-b-P4VP) in microfluidic channel. Different from the assembly of BCPs off-chip at the same solution properties, it is found that the fabricated SWMs are kinetically controlled assemblies with thermodynamic metastable structures, which are formed by orderly aggregation of preformed spherical micelles due to fast mixing process in microfluidic channels. Read More

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December 2018
4.457 Impact Factor

Role of electrostatic interactions in oil-in-water emulsions stabilized by heteroaggregation: an experimental and simulation study.

Langmuir 2018 Dec 3. Epub 2018 Dec 3.

Oil-in-water emulsion stabilization by heteroaggregation of hydrophilic particles without surfactant is of importance in a wide range of applications, however the stabilization mechanism is little described. To shed light on the early stage of the stabilization mechanism, a model system composed of an oil wax phase dispersed in water with oppositely charged colloidal particles, is studied experimentally and numerically. Experiments show that the colloids do not penetrate deeply in the oil phase suggesting that adsorption of the colloidal particles on the wax droplets is mainly due to electrostatic interactions. Read More

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December 2018