2,244 results match your criteria Colitis Ischemic


Colon Involvement in Necrotizing Pancreatitis: Incidence, Risk Factors, and Outcomes.

Ann Surg 2020 Jul 7. Epub 2020 Jul 7.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.

Objective: To investigate the incidence, risk factors, and outcomes of colon involvement in patients with necrotizing pancreatitis.

Summary/background Data: Necrotizing pancreatitis is characterized by a profound inflammatory response with local and systemic implications. Mesocolic involvement can compromise colonic blood supply leading to ischemic complications; however, few data exist regarding this problem. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004149DOI Listing

Reply to "Detailed Pathophysiology of Ischemic Colitis following Plasma Donation".

Intern Med 2020 Jun 30. Epub 2020 Jun 30.

Department of Critical and Intensive Care Medicine, Shiga University of Medical Science, Japan.

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http://dx.doi.org/10.2169/internalmedicine.5232-20DOI Listing

Detailed Pathophysiology of Ischemic Colitis following Plasma Donation.

Intern Med 2020 Jun 30. Epub 2020 Jun 30.

Second Department of Medicine, University of Toyama, Japan.

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http://dx.doi.org/10.2169/internalmedicine.4959-20DOI Listing

Ischemic Colitis in Buerger's Disease: Case Presentation and Review.

Cureus 2020 May 26;12(5):e8303. Epub 2020 May 26.

Clinical Gastroenterology & Internal Medicine, Merit Health Rankin & William Carey University College of Osteopathic Medicine, Brandon, USA.

Buerger's disease is a type of vasculitis that predominantly affects small to medium arteries and the veins of the upper and lower extremities. Intestinal vessels are rarely involved. This is a case report of a 38-year-old male, smoker, with known Buerger's disease who was found to have ischemic colitis of the sigmoid colon on biopsy and inferior mesenteric artery occlusion on computed tomography (CT) angiography. Read More

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http://dx.doi.org/10.7759/cureus.8303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317139PMC

Predictors of mortality following emergency open colectomy for ischemic colitis: a single-center experience.

World J Emerg Surg 2020 Jun 29;15(1):40. Epub 2020 Jun 29.

Unit of Digestive and HPB surgery, CARE Department, Henri Mondor Hospital, AP-HP, and Université Paris Est, UPEC, 51 Avenue du Maréchal de Lattre de Tassigny, 94010, Créteil, France.

Background: Ischemic colitis (IC) is a severe emergency in gastrointestinal surgery. The aim of the present study was to identify the predictors of postoperative mortality after emergent open colectomy for IC treatment. Additionally, we compared postoperative outcomes of patients undergoing emergent colectomy due to aortic surgery-related IC (AS-IC group) vs. Read More

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http://dx.doi.org/10.1186/s13017-020-00321-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325045PMC

[Chronic pancreatitis with IBS-like syndrome: approach to therapy].

Ter Arkh 2020 Apr 27;92(2):61-66. Epub 2020 Apr 27.

Sechenov First Moscow State Medical University (Sechenov University).

Aim: To determine approaches of the exacerbations treatment of chronic pancreatitis (CP) with IBS (irritable bowel syndrome)-like syndrome.

Materials And Methods: 312 patients with exacerbation of CP were observed and received standard therapy: antispasmodics, enzymes, proton pump inhibitors. 85 (27. Read More

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http://dx.doi.org/10.26442/00403660.2020.02.000518DOI Listing

All-cause and cause-specific mortality in microscopic colitis: a Danish nationwide matched cohort study.

Aliment Pharmacol Ther 2020 Jul 25;52(2):319-328. Epub 2020 Jun 25.

Department of Gastroenterology, Zealand University Hospital, Køge, Denmark.

Background: The long-term natural history of microscopic colitis remains uncertain.

Aim: To describe the mortality in a large unselected cohort of patients with microscopic colitis.

Methods: All Danish patients above 18 years with an incident diagnosis of microscopic colitis from 2001 to 2018 were identified from nationwide registries and compared to age- and sex-matched controls (variable 1:10 ratio). Read More

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http://dx.doi.org/10.1111/apt.15868DOI Listing

Abdominal Surgery in Patients with a Ventricular Assist Device: A Single Center Experience in Israel.

Isr Med Assoc J 2020 Jun;22(6):369-373

Surgical Division, Hillel Yaffe Medical Center, Hadera, Israel.

Background: Left ventricular assist devices (LVADs) are used more commonly in patients with advanced-stage heart failure. Some of these patients may require elective or urgent abdominal surgical procedures.

Objectives: To determine the outcomes of the management of LVAD-supported patients who underwent elective and urgent abdominal surgical procedures in our institution. Read More

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Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion.

World J Hepatol 2020 May;12(5):184-206

Departments of Pharmacology and Pathology, School of Medicine, University of Zagreb, Zagreb 10000, Croatia.

Background: The Pringle maneuver [portal triad obstruction(PTO)] provides huge disturbances during ischemia and even more thereafter in reperfusion. Contrarily, a possible solution may be stable gastric pentadecapeptide BPC 157, with already documented beneficial effects in ischemia/reperfusion conditions. Recently, BPC 157, as a cytoprotective agent, successfully resolved vessel occlusions in rats (ischemic colitis; deep vein thrombosis, superior anterior pancreaticoduodenal vein; bile duct cirrhosis) through rapid collateral vessel recruitment to circumvent vessel occlusion. Read More

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http://dx.doi.org/10.4254/wjh.v12.i5.184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280862PMC

Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial.

Sci Rep 2020 Jun 12;10(1):9537. Epub 2020 Jun 12.

Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark.

Remote ischemic conditioning (RIC) by repetitive brief periods of limb ischemia and reperfusion renders organs more resistant to ischemic injury. The protection is partly through down-regulation of the inflammatory response. Our aim was to investigate the clinical and anti-inflammatory effects of RIC in patients with active ulcerative colitis (UC). Read More

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http://dx.doi.org/10.1038/s41598-020-65692-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293253PMC
June 2020
5.078 Impact Factor

A rare case of myxedema ascites and uncommon complication of ischemic colitis.

Am J Emerg Med 2020 May 14. Epub 2020 May 14.

Department of Gastroenterology, SUNY Upstate Medical University, 750 E. Adams Street, Syracuse, NY 13210, USA. Electronic address:

Myxedema Ascites is a rare finding of primary hypothyroidism, thereby leading to delayed diagnosis. However, prompt treatment with levothyroxine leads to complete resolution of the condition. We present a rare case of myxedema ascites in an elderly female and highlight the importance of early diagnosis and management. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.05.021DOI Listing

Thoracic endovascular repair for retrograde acute type A aortic dissection as an alternative choice.

Gen Thorac Cardiovasc Surg 2020 Jun 10. Epub 2020 Jun 10.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, 6-1, Kishibeshinmachi, Suita, Osaka, Japan.

Objective: The purpose of this study was to determine the clinical outcomes of thoracic endovascular aortic repair in 8 patients with acute type A aortic dissection with an entry tear in the descending aorta.

Subjects And Methods: From January 2016 to December 2018, eight patients (mean age 76 years; range 54-92 years) were treated by thoracic endovascular aortic repair due to high operative risk for conventional open repair. All patients had significant comorbidities, and two had critical organ malperfusion due to aortic dissection. Read More

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http://dx.doi.org/10.1007/s11748-020-01397-0DOI Listing

[Contrast-Enhanced Ultrasound as a Diagnostic Tool in Diseases of the Digestive Tract].

Authors:
Daniel Weiss

Praxis (Bern 1994) 2020 ;109(8):615-630

Radiologie Spital STS-AG, Thun.

Contrast-Enhanced Ultrasound as a Diagnostic Tool in Diseases of the Digestive Tract Contrast-enhanced ultrasound is a good diagnostic tool in certain gastrointestinal diseases. Inflammation of the gastric and the bowel wall can often be distinguished from neoplastic alterations. Gastric and duodenal stenosis can be depicted with the use of oral contrast, and after stenting the patency can be documented. Read More

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http://dx.doi.org/10.1024/1661-8157/a003488DOI Listing
January 2020

Idiopathic myointimal hyperplasia of the mesenteric veins: Case report and review of the literature.

JGH Open 2020 Jun 27;4(3):345-350. Epub 2019 Dec 27.

Department of Pathology St Vincent's Hospital Fitzroy Victoria Australia.

In 1991, Genta and Haggitt described four patients with segmental ischemic colitis caused by idiopathic myointimal hyperplasia in the small mesenteric veins (IMHMV). There are now 33 published cases of IMHMV in the literature; however, this condition is still sufficiently rare that it poses a diagnostic challenge to pathologists and clinicians and is often clinically or histologically confused with inflammatory bowel disease (IBD) or ischemic colitis. IMHMV is characterized by intimal smooth muscle hyperplasia resulting in thickened small and medium-sized mesenteric veins (with arterial sparing). Read More

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http://dx.doi.org/10.1002/jgh3.12297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273708PMC

Coronavirus disease 2019 (COVID-19) and ischemic colitis: An under-recognized complication.

Am J Emerg Med 2020 May 27. Epub 2020 May 27.

Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, United States; Department of Infectious Disease, Saint Michael's Medical Centre, New York Medical College, NJ, United States.

COVID-19 has spread worldwide, with more than 2.5 million cases and over 80,000 deaths reported by the end of April 2020. In addition to pulmonary symptoms, gastrointestinal symptoms have been increasingly recognized as part of the disease spectrum. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.05.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251350PMC
May 2020
1.152 Impact Factor

M2 Macrophages and Phenotypic Modulation of Intestinal Smooth Muscle Cells Characterize Inflammatory Stricture Formation in the Rat.

Am J Pathol 2020 May 29. Epub 2020 May 29.

Gastrointestinal Diseases Research Unit and Queen's University, Kingston, Ontario, Canada. Electronic address:

The progression of Crohn disease to intestinal stricture formation is poorly controlled, and the pathogenesis is unclear, although increased smooth muscle mass is present. Earlier, stricture formation was described in the rat model of TNBS-induced colitis, now re-examined for early cellular features of stricture development. Although inflammation of the mid-descending colon typically resolved, a subset showed characteristic stricturing by day 16, with an inflammatory infiltrate in the neuromuscular layers that included eosinophils, CD3-positive T cells, and CD68-positive macrophages. Read More

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http://dx.doi.org/10.1016/j.ajpath.2020.05.015DOI Listing

Systematic review and meta-analysis on prophylactic aortic side branch embolization to prevent type II endoleaks.

J Vasc Surg 2020 May 19. Epub 2020 May 19.

Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.

Objective: Type II endoleaks are the most common type of endoleaks after EVAR and may cause late sac expansion and rupture. To prevent this, prophylactic embolization of aortic side branches has been suggested. The aim of this review was to assess the current evidence for this prophylactic treatment and its association with sac size enlargement, as well as rate of and re-intervention for type II endoleaks. Read More

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http://dx.doi.org/10.1016/j.jvs.2020.05.020DOI Listing

Endovascular Versus Open Repair for Ruptured Complex Abdominal Aortic Aneurysms: A Propensity Weighted Analysis.

Ann Vasc Surg 2020 May 18. Epub 2020 May 18.

Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA.

Background: This study evaluates 30-day mortality after endovascular aneurysm repair (EVAR) versus open repair for ruptured complex abdominal aortic aneurysms (cAAAs), including juxtarenal, pararenal, suprarenal, and extent IV thoracoabdominal aortic aneurysms (TAAA) in a real-world setting.

Methods: The Targeted Vascular Module from the American College of Surgeons National Surgical Quality Improvement Program was queried to identify patients undergoing repair for ruptured cAAA from 2011 to 2017. Primary endpoint was 30-day mortality. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.04.073DOI Listing

Surgical approach for acute ischemic colitis after scuba diving: A case report.

Ulus Travma Acil Cerrahi Derg 2020 May;26(3):482-485

Division of Colorectal Surgery, Department of General Surgery, Chonnam National University Hospital, Gwangju-Korea.

The clinical manifestations that may occur due to decompression during scuba diving vary widely, but only mild symptoms have been reported mainly in the gastrointestinal tract. In particular, ischemic colitis caused by air embolism is rare. We report a case of full-thickness ischemic colitis treated with failed conservative treatment but successfully treated surgically. Read More

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http://dx.doi.org/10.14744/tjtes.2019.67523DOI Listing

Hepatobiliary Scintigraphy in Cholecystocolonic Fistula.

Clin Nucl Med 2020 Aug;45(8):626-627

From the AdventHealth Medical Group Radiology at Central Florida, Orlando, FL.

We report a case of a 50-year-old man diagnosed with cholecystocolonic fistula (CCF), confirmed by scintigraphy. After negative initial radiologic workup, a colonoscopy revealed findings of right-sided ischemic colitis. Soon after, a febrile episode prompted a repeat abdominal CT scan demonstrating a possible CCF, later confirmed with a nuclear medicine hepatobiliary scintigraphy and treated surgically. Read More

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http://dx.doi.org/10.1097/RLU.0000000000003083DOI Listing

Mass-forming ischemic colitis that mimics colon cancer.

Chin Med J (Engl) 2020 May;133(10):1253-1254

Division of Colorectal Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.

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http://dx.doi.org/10.1097/CM9.0000000000000800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249714PMC

Fulminant Ischemic Pancolitis: A Severe Variant of Ischemic Colitis.

Cureus 2020 Apr 18;12(4):e7720. Epub 2020 Apr 18.

Surgery, Bethesda Hospital East, Boynton Beach, USA.

We present the case of a 75-year-old female with abdominal pain and a sudden change in mental status. She progressed rapidly with manifestations of acidosis without episodes of bloody bowel movements or diarrhea. The patient underwent emergent exploratory laparotomy, and a diagnosis of fulminant ischemic pancolitis was made with visual confirmation of infarcted colon from cecum to proximal rectum leading to subtotal colectomy and ileostomy. Read More

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http://dx.doi.org/10.7759/cureus.7720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233966PMC

Ischemic colitis induced by indigo naturalis in a patient with ulcerative colitis: a case report.

BMC Gastroenterol 2020 May 15;20(1):154. Epub 2020 May 15.

Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, 776, 1 Sunhwan-ro, Seowon-gu, Cheongju, 28644, Korea.

Background: Indigo naturalis is a Chinese herbal medicine that has currently been used to treat various inflammatory diseases, including ulcerative colitis. Recently, there are several reports concerning severe adverse events associated with indigo naturalis.

Case Presentation: We described a case of a 44-year-old female with ulcerative colitis who presented with lower abdominal pain and hematochezia. Read More

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http://dx.doi.org/10.1186/s12876-020-01301-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229623PMC

Nintedanib and ischemic colitis: Signal assessment with the integrated use of two types of real-world evidence, spontaneous reports of suspected adverse drug reactions, and observational data from large health-care databases.

Pharmacoepidemiol Drug Saf 2020 May 12. Epub 2020 May 12.

Uppsala Monitoring Centre, Uppsala, Sweden.

Purpose: Statistical screening of Vigibase, the global database of individual case safety reports, highlighted an association between the MedDRA Preferred Term (PT) "colitis" and nintedanib. Nintedanib is a protein kinase inhibitor authorized in accelerated regulatory procedures for the treatment of idiopathic pulmonary fibrosis (IPF). The aim of this report is to describe the integration of two types of real-world evidence, spontaneous reports of adverse drug reactions (ADR), and observational health data (OHD) in the assessment of a post-authorization safety signal of ischemic colitis. Read More

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http://dx.doi.org/10.1002/pds.5022DOI Listing

Curative embolization of iatrogenic inferior mesenteric arteriovenous fistula 14 years after right hemicolectomy.

Ann Gastroenterol 2020 May-Jun;33(3):318-320. Epub 2020 Mar 14.

Department of Radiology, Interventional Radiology Unit, AHEPA University Hospital of Thessaloniki (Adam Hatzidakis), Greece.

Inferior mesenteric arteriovenous fistula (IMAVF) is a rare condition with 40 reported cases. It can be of congenital, idiopathic or acquired etiology. Acquired IMAVF occurs after trauma or has an iatrogenic origin due to abdominal interventions, mainly operations involving the left hemi-colon. Read More

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http://dx.doi.org/10.20524/aog.2020.0463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196613PMC

Pathologic Manifestations of Gastrointestinal and Hepatobiliary Injury in Immune Checkpoint Inhibitor Therapy.

Arch Pathol Lab Med 2020 Apr 27. Epub 2020 Apr 27.

From the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.

Context.—: Immune checkpoint inhibitors (CPIs), including cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) inhibitors and the programmed death receptor-1 (PD-1)/programmed death ligand-1 (PD-L1) inhibitors, are being increasingly used for treating many advanced malignancies. However, CPI therapy is also associated with gastrointestinal and hepatobiliary adverse effects. Read More

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http://dx.doi.org/10.5858/arpa.2020-0070-RADOI Listing

Ischemic Colitis Associated with Low-volume Oral Sulfate Solution for Bowel Preparation.

Korean J Gastroenterol 2020 Apr;75(4):216-219

Departments of Internal Medicine, Wonkwang University Sanbon Hospital, Gunpo, Korea.

Ischemic colitis resulting from bowel preparation for colonoscopy is extremely rare, with only a small number of cases with polyethylene glycol having been reported. Here, we present a patient with ischemic colitis after administration of a low-volume oral sulfate solution (OSS). A 49-year-old female without any significant medical history experienced abdominal pain, vomiting, and hematochezia after ingestion of OSS. Read More

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http://dx.doi.org/10.4166/kjg.2020.75.4.216DOI Listing

Pre-operative endovascular occlusion for unresectable metastatic carcinoid tumor: technique and initial results.

Abdom Radiol (NY) 2020 Aug;45(8):2554-2560

Department of Radiology, Icahn School of Medicine at Mount Sinai Hospital, 1 Gustave Levy Place, Box 1234, New York, NY, 10029, USA.

Purpose: Surgery is the only curative therapy for carcinoid patients; however, many are unresectable due to direct involvement of the superior mesenteric artery (SMA) branches. In these patients, we sought to improve surgical outcomes via arterial skeletonization of the SMA prior to surgical resection.

Materials And Methods: After left radial access, the SMA was catheterized, angiography was performed, and balloon occlusion was achieved in the tumor vessel. Read More

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http://dx.doi.org/10.1007/s00261-020-02534-2DOI Listing

Gastrointestinal Ultrasound (GIUS) in Intestinal Emergencies - An EFSUMB Position Paper.

Ultraschall Med 2020 Apr 20. Epub 2020 Apr 20.

Haukeland University Hospital, National Centre for Ultrasound in Gastroenterology, Bergen, Norway.

An interdisciplinary group of European experts summarizes the value of gastrointestinal ultrasound (GIUS) in the management of three time-critical causes of acute abdomen: bowel obstruction, gastrointestinal perforation and acute ischemic bowel disease. Based on an extensive literature review, statements for a targeted diagnostic strategy in these intestinal emergencies are presented. GIUS is best established in case of small bowel obstruction. Read More

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http://dx.doi.org/10.1055/a-1147-1295DOI Listing

Major acute cardiovascular events in patients with inflammatory bowel disease.

Coron Artery Dis 2020 Apr 16. Epub 2020 Apr 16.

Department of Medicine, MedStar Washington Hospital Center, Washington, DC.

Background: Systemic inflammation and immune-mediated diseases have been associated with ischemic heart disease in addition to traditional risk factors. In this study, we investigate associations between inflammatory bowel disease (IBD) and acute cardiovascular events.

Methods: An observational study where patient data were extracted from our health system patient pool of 3 917 894. Read More

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http://dx.doi.org/10.1097/MCA.0000000000000899DOI Listing

Clinical outcomes after internal iliac artery embolization prior to endovascular aortic aneurysm repair.

Int Angiol 2020 Mar 26. Epub 2020 Mar 26.

Division of Vascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea -

Background: Aortic anatomy is important in determining the success or failure of endovascular aortic aneurysm repair (EVAR). Endoleak is another issue which should be addressed for a long-term durability of the procedure. Internal iliac artery (IIA) embolization is required to prevent type II endoleak when the iliac landing zone is not sufficient such that the iliac limb should be extended down to the external iliac artery (EIA). Read More

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http://dx.doi.org/10.23736/S0392-9590.20.04328-XDOI Listing

A case of stricture-type ischemic colitis from excessive alcohol consumption, with follow-up to rule out colon cancer.

Fukushima J Med Sci 2020 Apr 24;66(1):60-66. Epub 2020 Mar 24.

Department of Rheumatology, Fukushima Medical University School of Medicine.

A 69-year-old man was admitted to Hanawa Kousei Hospital with acute hepatitis attributed to alcohol consumption. His condition improved with conservative treatment. Computed tomography (CT) showed localized thickening of the colonic wall at the splenic flexure;carcinoembryonic antigen level was slightly elevated to 9. Read More

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http://dx.doi.org/10.5387/fms.2019-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7269883PMC

Low-profile Zenith Alpha™ Thoracic Stent Graft Modification Using Preloaded Wires for Urgent Repair of Thoracoabdominal and Pararenal Abdominal Aortic Aneurysms.

Ann Vasc Surg 2020 Mar 20. Epub 2020 Mar 20.

Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN. Electronic address:

Background: The aim of this study is to describe a modification technique using the low-profile Cook Zenith Alpha™ thoracic stent graft, and addition of a preloaded wire system, for urgent repair of pararenal (PRA) and thoracoabdominal (TAAA) aortic aneurysms.

Methods: We analyzed 20 consecutive patients who underwent urgent physician modified endograft repair (PMEG) of PRA and TAAA at 2 institutions. The low-profile Cook Zenith Alpha Thoracic stent graft was modified in accordance with each specific patient anatomic characteristics. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.02.022DOI Listing

Stent-assisted balloon dilatation of chronic aortic dissection.

J Thorac Cardiovasc Surg 2020 Feb 19. Epub 2020 Feb 19.

Department of Cardiac and Vascular Surgery; Hôpital Européen Georges Pompidou, AP-HP, Paris, France; INSERM U970, Faculté de Médecine Paris-Descartes, Université Paris 5, Paris, France.

Background: The treatment of complicated chronic aortic dissection remains controversial. We previously reported encouraging early results with the stent-assisted balloon-induced intimal disruption and relamination of aortic dissection (STABILISE) technique for treating complicated acute aortic dissections. However, to date there have been no specific reports on the treatment of complicated chronic aortic dissections with this technique. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2020.01.081DOI Listing
February 2020

Vasovagal Reaction and Ischemic Colitis Following Blood Donation.

Intern Med 2020 Jun 19;59(12):1515-1517. Epub 2020 Mar 19.

Department of Critical and Intensive Care Medicine, Shiga University of Medical Science, Japan.

Vasovagal reactions are the most common type of adverse reaction after blood donation; however, there are no reports of ischemic colitis as an adverse reaction after blood donation. A previously healthy 55-year-old woman suffered loss of consciousness at the end of her first plasma donation. She was diagnosed with a vasovagal reaction and received hydration. Read More

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http://dx.doi.org/10.2169/internalmedicine.4219-19DOI Listing

Polydeoxyribonucleotide Exerts Therapeutic Effect by Increasing VEGF and Inhibiting Inflammatory Cytokines in Ischemic Colitis Rats.

Biomed Res Int 2020 21;2020:2169083. Epub 2020 Feb 21.

Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

Ischemic colitis is resulted from an inadequate blood supply to a segment or entire colon. Polydeoxyribonucleotide (PDRN), extracted from salmon sperm, has been reported to exert anti-inflammatory and anti-ischemic effects through the adenosine A receptor (AR). We investigated whether PDRN possesses therapeutic effectiveness on ischemic colitis rats. Read More

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http://dx.doi.org/10.1155/2020/2169083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056995PMC
February 2020

Systemic Lupus Erythematosus Presenting with Ischemic Proctitis and Abdominal Compartment Syndrome.

Case Rep Gastrointest Med 2020 13;2020:5723403. Epub 2020 Feb 13.

Department of Medicine, Section of Pulmonary and Critical Care Medicine, West Virginia University, Morgantown, WV, USA.

Ischemic colitis and proctitis is a rare manifestation of systemic lupus erythematosus (SLE) and results from mesenteric vasculitis. Owing to diverse blood supply and presence of multiple collaterals, rectum is the least effected site in SLE enteritis. Ischemic proctocolitis as the presenting feature of SLE is exceedingly rare, with only three cases reported in the published scientific literature. Read More

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http://dx.doi.org/10.1155/2020/5723403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040385PMC
February 2020

Effects of Ginkgo biloba on Diseases Related to Oxidative Stress.

Planta Med 2020 Apr 25;86(6):376-386. Epub 2020 Feb 25.

Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Marília, São Paulo, Brazil.

(GB) is one of the most widely used phytotherapeutic products in the world, and its extract has beneficial properties for the treatment of several pathologies, such as diabetic cardiomyopathy, neurodegenerative diseases, cataracts, hearing loss, myocardial lesion, hippocampus neuronal lesions, morphometry testicular changes, and liver damage. This review aims to investigate the effects of GB on diseases related to oxidative stress. Databases such as MEDLINE/PUBMED and EMBASE were consulted, and PRISMA guidelines were used to build the review. Read More

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http://dx.doi.org/10.1055/a-1109-3405DOI Listing

Pneumatosis cystoides intestinalis induced by the alpha-glucosidase inhibitor complicated from sigmoid volvulus in a diabetic patient.

Int J Colorectal Dis 2020 May 24;35(5):943-946. Epub 2020 Feb 24.

Department of General and Digestive Surgery, Simone Veil Hospital, 14 rue Saint-Prix, 95600, Eaubonne, France.

Introduction: We present the case of a diabetic patient on treatment with acarbose who had presented a sigmoid volvulus with localized cystic pneumatosis of the sigmoid colon.

Case Report: A 72-year-old patient with a medical history of atrial fibrillation, DNID in treatment since 10 years by acarbose. The patient was admitted to the emergency for abdominal pain and occlusive syndrome since 48 h without fever or nausea or vomiting. Read More

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http://dx.doi.org/10.1007/s00384-020-03549-3DOI Listing

Distinct patterns of interleukin-12/23 and tumor necrosis factor α synthesis by activated macrophages are modulated by glucose and colon cancer metabolites.

Chin J Physiol 2020 Jan-Feb;63(1):7-14

Graduate Institute of Physiology, National Taiwan University College of Medicine, Taipei, Taiwan.

Chronic inflammation is a major risk factor for colitis-associated colorectal carcinoma (CRC). Macrophages play a key role in altering the tumor microenvironment by producing pro-inflammatory and anti-inflammatory cytokines. Our previous studies showed that glucose metabolism conferred death resistance for tumor progression and exerted anti-inflammatory effects in ischemic gut mucosa. Read More

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http://dx.doi.org/10.4103/CJP.CJP_75_19DOI Listing
February 2020

Association of decreased variation of coefficient R-R interval with ischemic colitis and small bowel obstruction.

PLoS One 2020 12;15(2):e0228117. Epub 2020 Feb 12.

Department of Gastroenterology, Hashimoto Municipal Hospital, Hashimoto, Wakayama, Japan.

Background: The parasympathetic nervous system exerts and controls intestinal tone. Several studies have suggested that the coefficient of the R-R intervals (CVRR) is useful for evaluating the parasympathetic nervous system.

Objectives: This study aimed to evaluate the relationship between gastrointestinal emergencies, specifically ischemic colitis (IC) and small bowel obstruction (SBO), and the autonomic nervous system. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228117PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015401PMC

A multiple myeloma patient who developed ischemic colitis during lenalidomide treatment: A rare case report.

J Oncol Pharm Pract 2020 Feb 6:1078155219900910. Epub 2020 Feb 6.

Hematology Clinic and Bone Marrow Transplantation Unit, University of Health Sciences Ankara, Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Ankara, Turkey.

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http://dx.doi.org/10.1177/1078155219900910DOI Listing
February 2020

[Colonic ischemia after open and endovascular aortic surgery : Epidemiology, Risk Factors, Diagnosis And Therapy].

Chirurg 2020 Feb;91(2):169-178

Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.

Despite the successful establishment of endovascular techniques, colonic ischemia continues to be a serious complication of aortic surgery.The risk factors for colonic ischemia include aortic aneurysm rupture, prolonged aortic clamping, perioperative hypotension, the need for catecholamine therapy, occlusion of the hypogastric arteries and renal insufficiency.The clinical presentation of postoperative colonic ischemia is often unspecific. Read More

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http://dx.doi.org/10.1007/s00104-020-01113-xDOI Listing
February 2020

Impact of comorbidity on hospitalizations in individuals newly diagnosed with multiple sclerosis: A longitudinal population-based study.

Mult Scler Relat Disord 2020 May 22;40:101955. Epub 2020 Jan 22.

College of Pharmacy & Nutrition, University of Saskatchewan, 107 Wiggins Rd, Saskatoon, SK S7N 5E5, Canada. Electronic address:

Background: It has been suggested that comorbidity in subjects with multiple sclerosis (MS) increases the risk of hospitalizations, although few studies have examined this, and rarely in an incident population.

Methods: Incident MS cases were identified retrospectively from administrative data in Saskatchewan, Canada (1996 - 2017) using a validated definition (≥3 hospital, physician or drug claims for MS); the date of the first claim for MS or a demyelinating condition was considered the index date. All hospitalizations occurring after the index were included in the analyses. Read More

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http://dx.doi.org/10.1016/j.msard.2020.101955DOI Listing

Successful surgical management of mesenteric inflammatory veno-occlusive disease.

Surg Case Rep 2020 Jan 21;6(1):27. Epub 2020 Jan 21.

Department of Pathology, Teikyo University School of Medicine, Tokyo, Japan.

Background: The term "mesenteric inflammatory veno-occlusive disease (MIVOD)" is used to describe an ischemic injury resulting from phlebitis or venulitis that affects the bowel or mesentery in the absence of arteritis. MIVOD is difficult to diagnose because of its rarity and frequent confusion with other diseases. The incidence and etiology of MIVOD remain unclear; only a few cases have been reported. Read More

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http://dx.doi.org/10.1186/s40792-020-0796-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973805PMC
January 2020

Clinical, imaging, endoscopic findings, and management of patients with CMV colitis: a single-institute experience.

Emerg Radiol 2020 Jun 18;27(3):277-284. Epub 2020 Jan 18.

Department of Radiology, University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Cleveland, OH, 44106, USA.

Purpose: To evaluate clinical, laboratory, imaging, endoscopic findings, treatment, and outcomes of patients with CMV colitis.

Methods: The electronic medical records of 652 patients who had an impression of colitis of unspecified etiology via endoscopic findings between 2011 and 2019 were retrospectively reviewed. There were 9 patients with biopsy-proven CMV colitis and associated CT imaging performed within 1 month of diagnosis. Read More

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http://dx.doi.org/10.1007/s10140-020-01750-zDOI Listing

Dosing of Antimycotic Treatment in Sepsis-Induced Liver Dysfunction by Functional Liver Testing with LiMAx®.

Case Rep Crit Care 2019 26;2019:5362514. Epub 2019 Dec 26.

Department of Anesthesiology, Surgical Intensive Care, Emergency and Pain Medicine, Ruhr University Bochum, Klinikum Herford, Herford, Germany.

Background: Sepsis-treatment is one of the major challenges in our time. Especially fungal infections play an important role in patient's morbidity and mortality. In patients with septic shock, liver function is often significantly impaired and therefore also hepatic drug metabolism is altered. Read More

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http://dx.doi.org/10.1155/2019/5362514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948309PMC
December 2019