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    4121 results match your criteria Cold Panniculitis

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    The Histopathological Spectrum of Pseudolymphomatous Infiltrates in Cutaneous Lupus Erythematosus.
    Am J Dermatopathol 2017 Jun 20. Epub 2017 Jun 20.
    *Research Unit Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria; †Anatomic Pathology Unit, Hospital Universitário Polydoro Ernani de São Thiago, Universidade Federal de Santa Catarina, Florianópolis, Brazil; ‡Anatomic Pathology Unit, Macerata General Hospital, Macerata, Italy; §Anatomic Pathology Unit, Department of Surgical Science and Integrated Diagnostics, University of Genoa, IRCCS AOU San Martino IST, Genoa, Italy; ¶Dermatopathology Unit, San Gallicano Dermatology Institute, Rome, Italy; ‖Department of Dermatology, Galliera Hospital, Genoa, Italy; **School of Pathology, University of Milan, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milan, Italy; and ††Department of Dermatology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
    The occurrence of pseudolymphomatous infiltrates in cutaneous lupus erythematosus (cLE) is described mainly in lupus panniculitis and lupus tumidus/lymphocytic infiltration of the skin (Jessner-Kanof). We collected 15 cases of pseudolymphomatous cLE other than lupus panniculitis and lupus tumidus (M:F = 4:11; age range: 23-79 years; mean age: 50.9 years; median age: 57 years). Read More

    Alpha-1 antitrypsin Pi*SZ genotype: estimated prevalence and number of SZ subjects worldwide.
    Int J Chron Obstruct Pulmon Dis 2017 8;12:1683-1694. Epub 2017 Jun 8.
    Pneumology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
    The alpha-1 antitrypsin (AAT) haplotype Pi*S, when inherited along with the Pi*Z haplotype to form a Pi*SZ genotype, can be associated with pulmonary emphysema in regular smokers, and less frequently with liver disease, panniculitis, and systemic vasculitis in a small percentage of people, but this connection is less well established. Since the detection of cases can allow the application of preventive measures in patients and relatives with this congenital disorder, the objective of this study was to update the prevalence of the SZ genotype to achieve accurate estimates of the number of Pi*SZ subjects worldwide, based on studies performed according to the following criteria: 1) samples representative of the general population, 2) AAT phenotyping characterized by adequate methods, and 3) selection of studies with reliable results assessed with a coefficient of variation calculated from the sample size and 95% confidence intervals. Studies fulfilling these criteria were used to develop tables and maps with an inverse distance-weighted (IDW) interpolation method, to provide numerical and geographical information of the Pi*SZ distribution worldwide. Read More

    A case of malignant peritoneal mesothelioma suggesting the utility of combining double-contrast radiography and endoscopy with computed tomography for diagnosis.
    Clin J Gastroenterol 2017 Jun 23. Epub 2017 Jun 23.
    Department of Gastroenterology, Kumamoto Chuo Hospital, 1-5-1, Tainoshima, Minami-ku, Kumamoto, Kumamoto, 862-0965, Japan.
    A 68-year-old woman presented with abdominal pain, weight loss, and vomiting. Enhanced computed tomography (CT) showed slightly increased density in the mesentery and edema of the third portion of the duodenum and proximal jejunum. Little ascites, but no primary lesion, lymph node metastases, or distant metastases, were observed. Read More

    High-frequency ultrasound features in a case of gouty panniculitis.
    Dermatol Online J 2017 Jun 15;23(6). Epub 2017 Jun 15.
    Department of Dermatology, Hospital Universitario Infanta Sofía, Madrid, Spain.
    Gouty panniculitis is caused by the deposition of urate crystals in the subcutaneous tissue, accompanied by a lobular panniculitis. It presents as subcutaneous nodules, most commonly located on the lower extremities. Being an unusual clinical presentation of gout, the sonographic findings of gouty panniculitis have been scarcely described in the literature. Read More

    Lupus mastitis as a first manifestation of systemic disease: About two cases with a review of the literature.
    Eur J Radiol 2017 Jul 6;92:124-131. Epub 2017 May 6.
    Centre de recherche et d'investigation des maladies du sein (CRID), Department of Radiology, Hôtel-Dieu de Montréal, Centre Hospitalier Universitaire de Montréal (CHUM), Canada.
    Lupus mastitis is an uncommon manifestation of systemic lupus erythematosus (SLE) that affects the subcutaneous fat in the breast, much like lupus panniculitis, but additionally involves the mammary gland. We report on two women for whom lupus mastitis was the initial manifestation of SLE and provide a literature review of 34 additional cases reported in the Anglo-Saxon and French literature since 1971, making this the largest review to date. Lupus mastitis (LM) can manifest clinically as subcutaneous masses that may be painful, or may present cutaneous involvement such as thickening and discolouration. Read More

    Panniculitis Associated with MEK Inhibitor Therapy: An Uncommon Adverse Effect.
    Case Rep Dermatol 2017 Jan-Apr;9(1):80-85. Epub 2017 Mar 21.
    aDepartment of Dermatology, Université Paul Sabatier-Toulouse III et Institut Universitaire du Cancer de Toulouse, Toulouse, France.
    The combination of MEK inhibitor (cobimetinib, trametinib) and BRAF inhibitor (vemurafenib, dabrafenib) is now the first-line treatment in patients with BRAF V600-mutated metastatic melanoma. This association reduces cutaneous adverse events induced by BRAF inhibitors alone, including photosensitivity, hand-foot syndrome, hyperkeratosis, alopecia, skin papillomas, keratoacanthomas, and squamous-cell carcinomas. While panniculitis has exceptionally been reported with BRAF inhibitors, this rare side effect has never been described with the use of MEK inhibitors. Read More

    Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and radiological features.
    BMC Gastroenterol 2017 Jun 13;17(1):75. Epub 2017 Jun 13.
    Department of Medicine, Division of Gastroenterology, Hospital of Trelleborg, Trelleborg, Sweden.
    Background: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis (MP) is a radiological finding and its relation to clinical SM is not fully understood. The aims of this study were to determine whether any correlation could be found between the radiological findings and the clinical disease course. Read More

    Pancreatic acinar cell carcinoma presenting with panniculitis, successfully treated with FOLFIRINOX: A case report.
    Mol Clin Oncol 2017 Jun 5;6(6):866-870. Epub 2017 May 5.
    Department of Comprehensive Clinical Oncology, Faculty of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
    Pancreatic acinar cell carcinoma (PACC) is a rare tumor of the exocrine pancreas, representing only 1% of all pancreatic malignancies. A 50-year-old man presented with edema of the thumb joints bilaterally, followed by an appearance of masses in the bilateral lower extremities and fever (38°C). The masses were diagnosed as panniculitis by skin biopsy, and multiple intraperitoneal masses were incidentally detected on pelvic magnetic resonance imaging performed to investigate the leg abnormalities. Read More

    Lysinibacillus massiliensis Panniculitis Masquerading as Erythema Nodosum: A Case Report.
    Open Forum Infect Dis 2017 6;4(2):ofx072. Epub 2017 Apr 6.
    Infectious Diseases.
    Lysinibacillus massiliensis, formerly Bacillus massiliensis, is an environmental Gram-positive bacillus that is generally non-pathogenic. Rare case reports in immunosuppressed patients have described sepsis with this organism. In this study, we report a case of L massiliensis as a cause of infectious panniculitis mimicking erythema nodosum after infusion of autologous adipose-derived stem cells in an immunosuppressed patient with refractory Crohn's disease. Read More

    Lupus profundus limited to a site of trauma: Case report and review of the literature.
    Int J Womens Dermatol 2017 Jun 5;3(2):117-120. Epub 2017 May 5.
    St. George Hospital, Sydney, Australia.
    Lupus erythematosus profundus (LEP) is a rare form of chronic cutaneous lupus erythematosus. We report on a case of a 56-year-old Caucasian woman who presented with a single, persistent, painful rash on the left hip and lateral aspect of the left upper thigh, which had been present for 2.5 years. Read More

    Cutaneous Manifestations of Medium- and Large-Vessel Vasculitis.
    Clin Rev Allergy Immunol 2017 May 26. Epub 2017 May 26.
    Université Pierre et Marie Curie-Paris VI, Assistance Publique-Hôpitaux de Paris, Service de Dermatologie-Allergologie, Hôpital Tenon, 4 rue de la Chine, 75020, Paris, France.
    Dermatologic manifestations are observed in almost all systemic vasculitides, even in large-and medium-vessel vasculitides, although such vessels are not found in the skin. Cutaneous manifestations may be related to a direct skin localization of the systemic vasculitis or a non-specific process associated with the vasculitis. According to the 2012 International Chapel Hill consensus, the two major variants of large-vessel vasculitides are Takayasu arteritis and giant-cell arteritis. Read More

    Bumps in the Road: Panniculitis in Children and Adolescents Treated with Vemurafenib.
    Pediatr Dermatol 2017 May;34(3):337-341
    Division of Dermatology, Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois.
    Vemurafenib is increasingly being used to treat nonmelanoma tumors that are positive for the BRAF V600E mutation. We report three children who presented with panniculitis induced by vemurafenib while undergoing treatment for central nervous system tumors and review the literature. Read More

    [Pathergic postsurgical-induced Pyoderma gangrenosum].
    Rev Med Liege 2017 May;72(5):227-232
    Service de Chirurgie Plastique, Esthétique et Reconstructrice, Clinique Saint-Vincent de Rocourt (CHC), Liège, Belgique.
    Pyoderma gangrenosum (PG) is a rare pustular and ulcerative inflammatory disease belonging to the group of neutrophilic dermatoses. It is frequently associated with systemic immune diseases. In this context the PG can be exceptionally triggered by tissue trauma such as surgery (pathergy). Read More

    Alpha-1-antitrypsin deficiency-related panniculitis: two cases with diverse clinical courses.
    Clin Exp Dermatol 2017 Jul 17;42(5):520-522. Epub 2017 May 17.
    Department of Dermatology, Galway University Hospital, Galway, Ireland.
    Alpha-1-antitrypsin deficiency (AATD)-related panniculitis is an extremely rare and underdiagnosed entity, and there is a paucity of data on its treatment. We report two cases of AATD-related panniculitis. The first was a 24-year-old woman with known AATD who presented with painful leg ulcers refractory to treatment with corticosteroids and colchicine. Read More

    Coinfection by Streptococcus phocae and cetacean morbillivirus in a short-beaked common dolphin Delphinus delphis.
    Dis Aquat Organ 2017 May;124(3):247-252
    Veterinary Histology and Pathology, Institute of Animal Health, Veterinary College, University of Las Palmas de Gran Canaria, Trasmontana s/n, Arucas 35413, Las Palmas de Gran Canaria, Spain.
    We describe gross, histopathological, and immunohistochemical features of Streptococcus phocae and cetacean morbillivirus coinfection in a short-beaked common dolphin Delphinus delphis. Major gross findings were cutaneous purulent nodules in the tail fluke, vegetative mitral valve endocarditis, and presumed postpartum pyometra. Histologic examination revealed bacterial septicemia characterized by widespread intravascular coccoid bacterial emboli. Read More

    Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat.
    JFMS Open Rep 2016 Jul-Dec;2(2):2055116916672786. Epub 2016 Oct 11.
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA.
    Case Summary: A domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs. Histopathologic examination of skin biopsies collected throughout the course of disease revealed chronic pyogranulomatous ulcerative dermatitis. Aerobic bacterial skin cultures yielded growth of a methicillin-resistant Staphylococcus aureus and Corynebacterium amycolatum. Read More

    Cutaneous Lymphomas with Cytotoxic Phenotype.
    Surg Pathol Clin 2017 Jun 28;10(2):409-427. Epub 2017 Mar 28.
    Dermatopathology Laboratory, St John's Institute of Dermatology, St Thomas' Hospital, South Wing, Staircase C, Westminster Bridge Road, London SE1 7EH, UK. Electronic address:
    Primary cutaneous cytotoxic lymphomas are T-cell or natural killer-cell lymphomas that express 1 or more cytotoxic markers. These neoplasms constitute a spectrum of diseases. In this review, an overview of clinical, morphologic, and phenotypical features of each subtype is provided. Read More

    Sonography of Dermatologic Emergencies.
    J Ultrasound Med 2017 May 4. Epub 2017 May 4.
    Departments of Imaging and Dermatology, Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues, Faculty of Medicine, University of Chile, Santiago, Chile.
    Dermatologic conditions may be the subjects of potential emergency consultations, and the knowledge of their sonographic appearance can facilitate an early diagnosis and management. In this pictorial essay, the sonographic dermatologic anatomy, technique, and conditions that can be supported by a prompt sonographic diagnosis are reviewed. The sonographic signs that may help diagnose these entities are discussed with a practical approach. Read More


    Skin manifestations among GATA2-deficient patients.
    Br J Dermatol 2017 Apr 25. Epub 2017 Apr 25.
    Dermatology Department, CHU Rennes, Rennes, France.
    GATA2 mutations have been identified in various diseases, such as monoMAC syndrome, Emberger syndrome, familial myelodysplastic syndrome, acute myeloid leukemia, and dendritic cell, monocyte, B and NK cell deficiency. These syndromes present a wide range of clinical features, dominated by severe infections and haematological disorders such as myelodysplastic syndrome. Up to 70% of GATA2-mutated patients have dermatological features, mainly genital or extra-genital warts, panniculitis or erythema nodosum, and lymphedema. Read More

    An unusual location of gouty panniculitis: A case report.
    Medicine (Baltimore) 2017 Apr;96(16):e6733
    aDepartment of Visceral Surgery bInstitute of Pathology, University Hospital CHUV, Lausanne, Switzerland.
    Rationale: Gouty panniculitis, characterised by the deposition of monosodium urate crystals in subcutaneous tissue, is a rare clinical manifestation of gout.

    Patient Concerns: The case of a 67-year-old man is reported, who presented an erythematous nodule on the upper part of the right buttock suspicious for an abscess. This was in the context of chemotherapy for non-Hodgkin's lymphoma. Read More

    Biological and clinical significance of tryptophan-catabolizing enzymes in cutaneous T-cell lymphomas.
    Oncoimmunology 2017 10;6(3):e1273310. Epub 2017 Feb 10.
    Department of Dermatology and Allergology, University of Helsinki and Helsinki University Central Hospital , Helsinki, Finland.
    Indoleamine 2,3-deoxygenase 1 (IDO1) induces immune tolerance in the tumor microenvironment (TME) and is recognized as a potential therapeutic target. We studied the expression of both IDO1 and the related tryptophan 2,3-dioxygenase (TDO) in several different subtypes of cutaneous T-cell lymphoma (CTCL), and evaluated the kynurenine (KYN) pathway in the local TME and in patient sera. Specimens from the total of 90 CTCL patients, including mycosis fungoides (MF, n = 37), lymphomatoid papulosis (LyP, n = 36), primary cutaneous anaplastic large cell lymphoma (pcALCL, n = 4), subcutaneous panniculitis-like T-cell lymphoma (SPTCL n = 13), and 10 patients with inflammatory lichen ruber planus (LRP), were analyzed by immunohistochemistry (IHC), immunofluorescence (IF), quantitative PCR, and/or liquid chromatography-tandem mass spectrometry (LC-MS/MS). Read More

    [Erythema nodosum : a panniculitis of diverse origins].
    Rev Med Liege 2017 Jan;72(1):43-44
    Service de Dermatologie, CHU de Liège, site du Sart Tilman, Liège, Belgique.
    Erythema nodosum is an acute nodular panniculitis, mainly affecting young women. Diverse etiologies are evoked, but the most frequent are sarcoidosis (Löfgren syndrome), streptococcal infections, yersiniosis and inflammatory enteropathies. Antalgic drugs and rest are usually adequate in this condition, which is spontaneously of favourable evolution. Read More

    Remission of subcutaneous panniculitis-like T-cell lymphoma in a pregnant woman after treatment with oral corticosteroids as monotherapy.
    JAAD Case Rep 2017 Mar 20;3(2):87-89. Epub 2017 Mar 20.
    Department of Dermatology, University of California at San Francisco, San Francisco, California; Department of Pathology, University of California at San Francisco, San Francisco, California.
    Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare form of cutaneous T-cell lymphoma characterized by neoplastic α/β T cells infiltrating subcutaneous tissues in a lobular pattern. Few data support the optimal treatment regimen for patients, given the rarity of this condition, and even fewer data describe treatment when diagnosed during pregnancy. We describe a case of SPTCL in a pregnant patient who achieved clinical remission after treatment with corticosteroid monotherapy. Read More

    Idiopathic pleural panniculitis with recurrent pleural effusion not associated with Weber-Christian disease.
    Open Med (Wars) 2016 19;11(1):394-398. Epub 2016 Nov 19.
    Department of Medicine and Surgery, University of Salerno, Baronissi Campus, Via S. Allende, 84081 Baronissi, Salerno, Italy.
    A 82-year-old patient with dyspnea and a recurrent history of pleural effusion was admitted into our unit. He performed a Chest computed tomography showing right pleural effusion. Video-assisted thoracoscopy (VATS) exploratory showed parietal pleural thickening of adipose tissue. Read More

    Nódulos subcutáneos faciales de 3 meses de evolución.
    Dermatol Online J 2017 Feb 15;23(2). Epub 2017 Feb 15.
    Dermatology Department, Dermatologist, Complejo Hospitalario de Granada, Granada, Spain.
    Siliconomas are subcutaneous nodules that usuallyappear as a consequence of the migration of freesilicon implanted in other locations. They are morefrequent in women with abnormal breast implants,such as poly implant prostheses (PIP), but they may alsoappear after illegal injection of free silicone. We reporta 57-year-old woman who attended our Dermatologyclinic complaining of relapsing facial panniculitis ofunknown origin. Read More


    Combination of dabrafenib plus trametinib for BRAF and MEK inhibitor pretreated patients with advanced BRAF(V600)-mutant melanoma: an open-label, single arm, dual-centre, phase 2 clinical trial.
    Lancet Oncol 2017 Apr 4;18(4):464-472. Epub 2017 Mar 4.
    Department of Medical Oncology, UZ Brussel, Brussels, Belgium. Electronic address:
    Background: Patients with BRAF(V600)-mutant melanoma benefit from treatment with the combination of BRAF and MEK inhibitors, but resistance and disease progression develops in most patients. Preclinical studies and case studies have indicated that acquired resistance to BRAF inhibition can be reversible. We aimed to assess the anti-tumour activity of rechallenge with BRAF plus MEK inhibition in a prospective clinical trial. Read More

    Bacteremia with Raoultella planticola in the setting of acute pancreatitis complicated with acute cholangitis.
    Rev Esp Enferm Dig 2017 Jun;109(6):479
    Aparato digestivo, Hospital Universitario de Guadalajara.
    The bacterium Raoultella planticola (R planticola) is a rare pathogen in humans. We report a case of mild acute pancreatitis (MAP) of biliary origin with cholangitis and bacteremia with R planticola in association with pancreatic panniculitis (PP). We present the case report of a 55-year-old woman. Read More

    Sclerosing mesenteritis: a systematic review of 192 cases.
    Clin J Gastroenterol 2017 Apr 14;10(2):103-111. Epub 2017 Feb 14.
    Gastroenterology Center of Connecticut, Clinical Instructor of Medicine, Yale University School of Medicine, Hamden, 06518, CT, USA.
    Introduction: Sclerosing mesenteritis includes a spectrum of inflammatory disorders involving the adipose tissue of the bowel mesentery.

    Aim: To perform a systematic review of previously reported cases of sclerosing mesenteritis (SM) to determine the epidemiology, risk factors, methods of diagnosis, treatment patterns and outcomes for this disease.

    Methods: Medline, PubMed, Google Scholar and Cochrane database were searched using keywords mesenteric panniculitis, retractile mesenteritis, mesenteric lipodystrophy and sclerosing mesenteritis. Read More

    Lipophagic Panniculitis of Childhood: A Case Report and Comprehensive Review of the Literature.
    Am J Dermatopathol 2017 Mar;39(3):217-224
    *Weill Cornell Medical College, New York, NY; andDepartments of †Dermatology, and‡Pathology and Laboratory Medicine, NYPH-Weill Cornell Medicine, New York, NY.
    Lipophagic panniculitis of childhood is a rare condition notable clinically for an inflammatory panniculitis followed by the development of permanent lipoatrophy. In this regard, the term lipoatrophic panniculitis has been used synonymously with lipophagic panniculitis. Additional designations include lipophagic lipoatrophic panniculitis and annular lipoatrophic panniculitis of the ankles. Read More

    [An analysis of clinical characteristics of twelve cases of mesenteric panniculitis].
    Zhonghua Nei Ke Za Zhi 2017 Feb;56(2):112-115
    Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
    Objective: Mesenteric panniculitis is an idiopathic, uncommon disease involving the adipose tissue of mesentery. The etiology, diagnosis and treatment are still unnoticed. We thus reported a case series to improve the understanding of this rare disorder. Read More

    Pancreatitis, panniculitis and polyarthritis (PPP-) syndrome caused by post-pancreatitis pseudocyst with mesenteric fistula. Diagnosis and successful surgical treatment. Case report and review of literature.
    Int J Surg Case Rep 2017 18;31:170-175. Epub 2017 Jan 18.
    University Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Electronic address:
    Introduction: Pancreatitis, panniculitis and polyarthritis syndrome is a very rare extra-pancreatic complication of pancreatic diseases.

    Presentation Of Case: While in most cases this syndrome is caused by acute or chronic pancreatitis, we report a case of a 62-year-old man presenting with extensive intraosseous fat necrosis, polyarthritis and panniculitis caused by a post-pancreatitis pseudocyst with a fistula to the superior mesenteric vein and extremely high blood levels of lipase. This became symptomatic 2. Read More

    [Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature].
    Korean J Gastroenterol 2017 Jan;69(1):83-86
    Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
    Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease. It has been postulated that pancreatic panniculitis is caused by the systemic activity of pancreatic enzymes that lead to microcirculatory disturbances. We report a 41-year-old heavy alcoholic woman with pancreatic panniculitis that coexisted with acute and chronic pancreatitis. Read More

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