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    Severe panniculitis and polyarthritis caused by acinar cell carcinoma arising from an ectopic pancreas.
    BMJ Case Rep 2017 Nov 21;2017. Epub 2017 Nov 21.
    Department of Pathology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium.
    The pancreatitis, panniculitis and polyarthritis (PPP) syndrome is a rare condition caused by pancreatic diseases, such as acute or chronic pancreatitis or pancreatic carcinoma. We report the first case of PPP syndrome caused by metastatic acinar cell carcinoma from an ectopic pancreas. The symptoms were successfully managed by the treatment of the metastatic carcinoma. Read More

    Analysis of Bacterial and Fungal Nucleic Acid in Canine Sterile Granulomatous and Pyogranulomatous Dermatitis and Panniculitis.
    Vet Pathol 2017 Jan 1:300985817738316. Epub 2017 Jan 1.
    1 Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
    Next generation sequencing (NGS) studies are revealing a diverse microbiota on the skin of dogs. The skin microbiota of canine sterile granulomatous and pyogranulomatous dermatitis (SGPD) has yet to be investigated using NGS techniques. NGS targeting the 16S rRNA and ITS-1 region of bacterial and fungal DNA, respectively, were used to investigate if bacterial and fungal DNA were associated with skin lesions in cases of canine SGPD. Read More

    Paradoxical Adipose Hypertrophy (PAH) After Cryolipolysis.
    Aesthet Surg J 2017 Nov 14. Epub 2017 Nov 14.
    Plastic and Aesthetic Surgery Department, Hopital Tenon, Paris, France. Private practice, Paris, France. Department of Dermatology, Hopital Tenon, Paris, France. Anatomopathology Laboratory, Hopital Tenon, Paris, France.
    Background: Cryolipolysis is a minimally invasive technique used to decrease local adipose tissue by thermal cooling. Paradoxical adipose hypertrophy (PAH) is a rare complication of cryolipolysis with important aesthetic consequences.

    Objectives: The objective of this study was to describe four cases of PAH after a cryolipolysis treatment. Read More

    Sclerosing mesenteritis diagnosed with computed tomography and ultrasound-guided needle biopsy: the utility of the coaxial technique.
    Clin J Gastroenterol 2017 Nov 16. Epub 2017 Nov 16.
    Department of Gastroenterology and Hepatology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, Okayama, 710-8602, Japan.
    Here we report a case of sclerosing mesenteritis that we diagnosed with needle biopsy under the guidance of computed tomography (CT) and ultrasound (US) observation. An 82-year-old woman presented with appetite loss, weight loss and epigastric pain. CT of the abdomen and pelvis revealed increased density of the mesentery adjacent to the small bowel and enlarged lymph nodes. Read More

    Post-irradiation morphoea of the breast: a case report and review of the literature.
    Histopathology 2017 Aug 14. Epub 2017 Aug 14.
    Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
    We describe a 44-year-old female with triple-negative breast cancer who developed skin erythaema, sclerosis and contracture of her entire right breast 15 months after completion of post-lumpectomy chemotherapy and radiotherapy, consistent with post-irradiation morphoea (PIM). PIM is a rare complication of breast irradiation that impairs a patient's quality of life. PIM is located usually at the radiation port or in the surrounding tissue. Read More

    Subcutaneous Panniculitis-Like T-Cell Lymphoma Presenting as a Local Inflammation of a Thigh in an 8-Month-Old Child.
    European J Pediatr Surg Rep 2017 Jan 28;5(1):e68-e70. Epub 2017 Oct 28.
    Department of Pediatrics, Hematology and Oncology, Pomorski Uniwersytet Medyczny w Szczecinie, Szczecin, Poland.
    During infancy, skin inflammation is usually treated in basic pediatric care. In this study, we present a case of an 8-month-old girl with a 2-month history of an inflammation of the thigh treated locally by ointments and oral antibiotics in basic and dermatological care. The patient had a history of fever, sweating, and failure to thrive. Read More

    An Unexpected Etiology of Pancreatic Panniculitis: A Case Report.
    J Pancreat Cancer 2017 1;3(1):1-4. Epub 2017 Jan 1.
    Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213.
    Background: Pancreatic panniculitis is a rare cause of subcutaneous fat necrosis secondary to elevated serum levels of pancreatic enzymes. It is most often associated with pancreatic acinar cell carcinoma, but has also been seen in patients with pancreatitis.

    Case Report: We present a case of a 64 year old Caucasian man without symptoms of pancreatitis who presents with pancreatic panniculitis manifesting in multiple subcutaneous ulcerating nodules of the bilateral lower extremities, discovered to have a previously unreported etiology for this condition. Read More

    Sterile nodular panniculitis with lung and lymph node involvement in a Siberian tiger (Panthera tigris altica).
    J Vet Med Sci 2017 Oct 30. Epub 2017 Oct 30.
    State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.
    A 2- to 4-year-old uncastrated male Siberian tiger (Panthera tigris altica) bred in a local wild animal park presented with generalized clinical signs including abdominal pain, fever, lethargy, and anorexia, along with subcutaneous nodules along the trunk. The patient subsequently died of chronic, progressive dyspnea despite 45 days of antibiotic treatment. At necropsy, mesenteric fat inflammation and multiple subcutaneous, peritoneal, and intraabdominal nodules were observed. Read More

    An Overlooked Potentially Treatable Disorder: Idiopathic Mesenteric Panniculitis.
    Med Princ Pract 2017 Oct 26. Epub 2017 Oct 26.
    Objective: The aim of this study was to determine the prevalence of mesenteric panniculitis (MP) and to describe its clinical characteristics, therapy and outcome.

    Subjects And Methods: This retrospective study was carried out among patients defined as MP according to computed tomography (CT) scans from January 2012 to December 2015. The CT images were reanalyzed by study radiologists to confirm the previous MP diagnosis. Read More

    Primary Cutaneous Acral CD8(+) T-Cell Lymphoma.
    Arch Pathol Lab Med 2017 Nov;141(11):1469-1475
    From the Sections of Hematopathology (Drs Hathuc and Smith) and Dermatopathology (Dr Hristov) in the Department of Pathology, University of Michigan Medical Center, Ann Arbor.
    Primary cutaneous acral CD8(+) T-cell lymphoma is a new provisional entity in the 2016 revision of the World Health Organization classification of lymphoid neoplasms. This is a challenging diagnosis because of its rarity, as well as its morphologic and immunophenotypic overlap with other CD8(+) cytotoxic lymphoid proliferations. Appropriate classification of this entity is crucial because of its indolent clinical behavior compared with other CD8(+) T-cell lymphomas. Read More

    SELF-HEALING JUVENILE CUTANEOUS MUCINOSIS: Clinical and histopathologic findings of nine cases: the relevance of long-term follow-up.
    J Am Acad Dermatol 2017 Oct 21. Epub 2017 Oct 21.
    Department of Dermatology, Centre National de Référence des Maladies Génétiques à Expression Cutanée (MAGEC), Hôpital Universitaire Necker-Enfants Malades, APHP, Paris, France; Unité INSERM U 1163, University Paris-Descartes; Institut Imagine, Sorbonne Cité University, Paris, France.
    Background: Self-healing juvenile cutaneous mucinosis (SHJCM) is a rare disorder and the pathogenesis and long-term prognosis are unknown.

    Objectives: To elucidate the clinical and histopathologic characteristics, pathogenesis and outcome in patients with SHJCM.

    Methods: Retrospective study of 9 patients with SHCJM. Read More

    Orbital T-cell lymphoma versus lupus panniculitits: a T-cell-mediated spectrum of orbital lymphoproliferative disease.
    Orbit 2017 Oct 17:1-3. Epub 2017 Oct 17.
    b The Oculoplastic and Orbital Surgery Department of Wills Eye Hospital , Thomas Jefferson University Hospital , Philadelphia , PA , USA.
    This is a case description of a single male patient found to have T-cell-mediated inflammation and lymphoproliferation of the orbit. Chronic T-cell-mediated inflammatory disease can pose a diagnostic challenge particularly in its differentiation from a neoplastic process. The histopathology in this case demonstrated features of both lupus erythematosus panniculitis and features of orbital T-cell lymphoma. Read More

    Cold-Induced Dermatoses: Case Report and Review of Literature.
    Am J Dermatopathol 2017 Sep 27. Epub 2017 Sep 27.
    *Department of Anatomic Pathology, University Hospital Jose Eleuterio Gonzalez, Monterrey, Mexico; †Department of Dermatology, West Virginia University, Morgantown, WV; and ‡Department of Pathology, West Virginia University, Morgantown, WV.
    Cold panniculitis and perniosis are the most common cold-induced dermatologic disorders and are clinically characterized by indurated and erythematous nodules and plaques that develop at sites exposed to excessive cold and wet conditions. Cold panniculitis is most commonly seen in infants, but adult cases involving the thighs of equestrians are well known and have come to be known as equestrian cold panniculitis or equestrian perniosis. Recently, similar cases have been described in nonequestrian settings with the prolonged use of ice-packs or other cold-therapy devices. Read More

    Associations between anti-melanoma differentiation-associated gene 5 antibody and demographics, clinical characteristics and laboratory results of patients with dermatomyositis: A systematic meta-analysis.
    J Dermatol 2017 Oct 6. Epub 2017 Oct 6.
    Department of Rheumatology, Huai'an First People's Hospital, Nanjing Medical University, Jiangsu, China.
    Anti-melanoma differentiation-associated gene 5 (MDA5) antibody is a specific biomarker in patients with dermatomyositis (DM). Results from several studies that examined the relationship between anti-MDA5 antibody and the demographics, clinical characteristics and laboratory results of DM patients have been conflicting. The purpose of this study was to identify the relationship, if any, of anti-MDA5 antibody with demographics, clinical characteristics and laboratory results of DM patients. Read More

    Sclerosing mesenteritis: a benign cause of mesenteric mass lesions.
    Pan Afr Med J 2017 28;27:228. Epub 2017 Jul 28.
    Surgery Service, Hospital Center Lisboa Central, Lisboa, Portugal.
    Sclerosing mesenteritis is a rare disease of the mesentery. Associations with surgery, trauma, autoimmunity and paraneoplastic syndrome have been suggested, but most of the cases remain idiopathic. Diagnosis is often incidental, based upon the finding of a single or multiple mesenteric lesions on abdominal CT and histopathological confirmation. Read More

    Variation in Clinical Characteristics of Women versus Men Preoperative for Laparoscopic Roux-en-Y Gastric Bypass: Analysis of 83,059 Patients.
    Am Surg 2017 Sep;83(9):947-951
    Variation by sex in preoperative clinical characteristics of female and male laparoscopic Roux-en-Y gastric bypass (LRYGB) patients has not been evaluated comprehensively. The objective of our study was to identify clinical differences between morbidly obese women and men seeking LRYGB. Data from 83,059 patients in the Surgical Review Corporation's Bariatric Outcomes Longitudinal Database who were about to undergo LRYGB was analyzed in two groups: women (n = 65,325) and men (n = 17,734). Read More

    Nodular Vasculitis in a Patient With Crohn's Disease on Vedolizumab.
    Am J Dermatopathol 2017 Sep 20. Epub 2017 Sep 20.
    *Division of Dermatology, University of California, Los Angeles, CA; and †Department of Dermatology, University of California, Irvine, Irvine, CA.
    Erythema induratum (EI), or nodular vasculitis (NV), is a type of panniculitis that is often associated with vasculitis affecting various-sized veins, venules, and arteries in reaction to various causative factors. Historically, EI was highly linked to tuberculosis, but in 1946, Montgomery first proposed the term NV to describe cases of EI not associated with tuberculosis. Only 2 reports of NV associated with inflammatory bowel disease have been reported in the literature. Read More

    Self-limiting Ibrutinib-Induced Neutrophilic Panniculitis.
    Am J Dermatopathol 2017 Sep 20. Epub 2017 Sep 20.
    Department of Dermatology, UT Southwestern Medical Center, Dallas, TX.
    Neutrophilic panniculitis is a relatively rare condition, characterized by predominantly neutrophilic inflammation in the subcutaneous fat. Rarely, neutrophilic panniculitis may be induced by chemotherapeutics or targeted molecular therapies, including the Bruton tyrosine kinase inhibitor ibrutinib. Previously reported cases of ibrutinib-induced panniculitis were suppressed with sustained low-dose steroid therapy while continuing ibrutinib therapy. Read More

    A case of leprosy, erythema nodosum leprosum, and hemophagocytic syndrome: A continuum of manifestations of same agent-host interactions.
    Intractable Rare Dis Res 2017 Aug;6(3):230-233
    Department of Medicine, All India Institute of Medical Sciences, Delhi, India.
    A young adult man with 4-years history of lepromatous leprosy (received irregularly multidrug therapy) presented with two and half years history of symptoms suggestive of chronic erythema nodosum leprosum (ENL), initially responded to steroids and thalidomide, but later on failed. During the last 2-months, he developed fever, vomiting, and subsequently altered sensorium. On evaluation, he had hepatosplenomegaly, hyponatremia, hyperferritinemia, hemophagocytosis in bone marrow aspiration, lobular panniculitis in skin biopsy, and multiple parenchymal nodules in chest imaging. Read More

    Subcutaneous Fat Necrosis of the Newborn With Initial Hypocalcemia and Familial Recurrence: A Case Report.
    J Cutan Med Surg 2017 Sep 1:1203475417733459. Epub 2017 Sep 1.
    1 Division of Paediatric Medicine, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, Canada.
    Subcutaneous fat necrosis of the newborn (SFNN) is a rare disorder characterised by indurated plaques or nodules with or without erythema, typically distributed over the cheeks, extremities, posterior trunk, buttocks, and thighs, and appears during the first 2 weeks of life. It is commonly associated with perinatal asphyxia and, while usually self-limited, can lead to severe hypercalcemia. There is no known familial association. Read More

    Alpha-1-antitrypsin deficiency: Genetic variations, clinical manifestations and therapeutic interventions.
    Mutat Res 2017 Jul 18;773:14-25. Epub 2017 Mar 18.
    Department of Biotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, India. Electronic address:
    Alpha-1-antitrypsin (AAT) is an acute phase secretory glycoprotein that inhibits neutrophil proteases like elastase and is considered as the archetype of a family of structurally related serine-protease inhibitors termed serpins. Serum AAT predominantly originates from liver and increases three to five fold during host response to tissue injury and inflammation. The AAT deficiency is unique among the protein-misfolding diseases in that it causes target organ injury by both loss-of-function and gain-of-toxic function mechanisms. Read More

    Diagnosis of mesenteric panniculitis in the multi-detector computed tomography era. Association with malignancy and surgical history.
    Saudi Med J 2017 Oct;38(10):1013-1018
    Diagnostic Radiology Department, The Jordan University Hospital, Amman, Jordan. E-mail.
    Objectives: To assess the prevalence and associations of mesenteric panniculitis (MP) using multi-detector CT (MDCT).

    Methods: This retrospective study included 4758 consecutive patients who underwent abdomino-pelvic MDCT between January 2012 and December 2014 at Jordan University Hospital, Amman, Jordan. Radiological database was searched for MP diagnosis and patients with suspected MP were re-evaluated by an experienced radiologist to confirm the diagnosis. Read More

    [Pathologic subtyping of primary lymphoma of breast and prognostic analysis].
    Zhonghua Bing Li Xue Za Zhi 2017 Sep;46(9):618-622
    Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
    Objective: To investigate the pathological types and prognostic factors of primary lymphoma of breast (PLB). Methods: The clinical pathological data of 115 cases of PLB during October 2006 to October 2016 were retrospectively analyzed, and the basic clinical and pathological data, pathology types and the immunohistochemical slides by EliVision two-step method for staining were summarized. Results: Almost all the patients were women (113/115), and the median age was 52 years old (range: 27 to 81 years old). Read More

    Erythema nodosum-like panniculitis mimicking disease recurrence: A novel toxicity from immune checkpoint blockade therapy-Report of 2 patients.
    J Cutan Pathol 2017 Dec 13;44(12):1080-1086. Epub 2017 Oct 13.
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
    Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed substantial therapeutic benefit in patients with clinically advanced solid malignancies. However, autoimmune toxicities are common and often significant adverse events with these agents. While rash and pruritus remain the most common cutaneous complications in treated patients, novel dermatologic toxicities related to immune checkpoint blockade continue to emerge as the number of patients exposed to immunotherapy increases. Read More

    Pseudomembranous changes in the dermis: A novel observation and potential clue for evolving lipodermatosclerosis?
    J Cutan Pathol 2017 Dec 19;44(12):1070-1074. Epub 2017 Sep 19.
    Department of Pathology, Western General Hospital and the University of Edinburgh, Edinburgh, UK.
    Lipodermatosclerosis (LDS) is a well-recognized form of fibrosing panniculitis. Although chronic cases are readily diagnosed, early and evolving lesions may be clinically mistaken for cellulitis and other forms of panniculitis. Most pathologists are familiar with a pseudomembranous type of fat necrosis as a useful feature of chronic LDS. Read More

    Oral and maxillofacial non-Hodgkin lymphomas: Case report with review of literature.
    Medicine (Baltimore) 2017 Sep;96(35):e7890
    aDepartment of Head Neck Surgery, Hainan Cancer Hospital, Haikou, Hainan bDepartment of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
    Rationale: Lymphomas take up about 14% of all head-neck malignancies, out of which 97% are non-Hodgkin lymphomas (NHL). The clinical courses, treatment responses, and prognoses of NHLs vary with different subtypes and anatomic sites. In the Chinese population (including the Taiwanese), head-neck NHLs are often seen with the tonsils, nasal cavity, nasal sinus, and the nasopharynx. Read More

    Pancreatic Panniculitis and Polyarthritis.
    Curr Rheumatol Rep 2017 Aug 26;19(10):62. Epub 2017 Aug 26.
    Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Ulmenweg 18, 91054, Erlangen, Germany.
    Purpose Of Review: Polyarthritis can have numerous reasons and may thus constitute a challenge for differential diagnosis. One rare potential reason for sterile polyarthritis is underlying pancreatic disease with systemic hyperlipasemia, most often accompanied by painful skin lesions caused by a subcutaneous inflammatory process known as panniculitis. Systematic evidence on pancreatic panniculitis and polyarthritis is limited, particularly regarding its feature as facultative paraneoplasia with underlying intra- or even extra-pancreatic malignancy. Read More

    [(18)F-FDG PET/CT Manifestation and Clinical Analysis of Subcutaneous Panniculitis-Like T-Cell Lymphoma].
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 2017 Aug;25(4):1047-1052
    Department of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
    Objective: To explore the clinical presentation, imaging characteristics of (18)F-FDG PET/CT and prognosis of patients with subcutaneous panniculitis-like T-cell lymphoma (SPTCL).

    Methods: The images and clinical data of 7 patients with pathologically confirmed SPTCL who underwent (18)F-FDG PET/CT were retrospectively analyzed.

    Results: Six patients displayed multiple subcutaneous nodules or deeply seated plaques, most commonly on the extremities and trunk, and one patient showed a single lesion on his face. Read More

    Immunohistochemistry reveals an increased proportion of MYC-positive cells in subcutaneous panniculitis-like T-cell lymphoma compared with lupus panniculitis.
    J Cutan Pathol 2017 Nov 6;44(11):925-930. Epub 2017 Sep 6.
    Department of Pathology, Stanford University School of Medicine, Stanford, California.
    Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a malignant primary cutaneous T-cell lymphoma that shares significant clinical, histopathologic and immunophenotypic overlap with lupus erythematosus panniculitis (LEP).

    Methods: We performed immunohistochemistry for the MYC oncoprotein on 23 cases of SPTCL (1 CD8 negative) and 12 cases of LEP to evaluate if there are quantitative or qualitative differences in protein expression of this marker in these entities.

    Results: In SPTCL cases, the percentage of all cells that were c-Myc positive ranged from 0. Read More

    Clinical Practice Recommendations on Indication and Timing of Hematopoietic Cell Transplantation in Mature T Cell and NK/T Cell Lymphomas: An International Collaborative Effort on Behalf of the Guidelines Committee of the American Society for Blood and Marrow Transplantation.
    Biol Blood Marrow Transplant 2017 Nov 7;23(11):1826-1838. Epub 2017 Aug 7.
    Vanderbilt University Medical Center, Nashville, Tennessee.
    Recognizing the significant biological and clinical heterogeneity of mature T cell and natural killer (NK)/T cell lymphomas, the American Society for Blood and Marrow Transplantation invited experts to develop clinical practice recommendations related to the role of autologous hematopoietic cell transplantation (auto-HCT) and allogeneic HCT (allo-HCT) for specific histological subtypes. We used the GRADE methodology to aid in moving from evidence to decision making and ultimately to generating final recommendations. Auto-HCT in front-line consolidation is recommended in peripheral T cell lymphoma not otherwise specified (PTCL-NOS), angioimmunoblastic T cell lymphoma (AITL), anaplastic large cell lymphoma-anaplastic lymphoma kinase (ALCL-ALK)-negative, NK/T cell (disseminated), enteropathy-associated T cell lymphoma (EATL), and hepatosplenic lymphomas. Read More

    Mucocutaneous Manifestations in Patients with Rheumatoid Arthritis: A Cross-sectional Study from Eastern India.
    Indian J Dermatol 2017 Jul-Aug;62(4):411-417
    Department of Dermatology, Venereology, and Leprosy, R. G. Kar Medical College, Kolkata, West Bengal, India.
    Background: Cutaneous manifestations are fairly common in rheumatoid arthritis (RA) and they can help in early diagnosis, prompt treatment, and hence reduced morbidity from the disease.

    Aims: The objective of the present study was to find out the different patterns of dermatoses in a group of patients with RA from Eastern India.

    Methodology: Consecutive patients fulfilling the American Rheumatism Association 1987 revised criteria for the classification of RA and who had different dermatoses were included in this cross-sectional study done over a period of 8 years in a tertiary care hospital in Eastern India. Read More

    Erythema Ab Igne Caused By Laptop Computer.
    Open Access Maced J Med Sci 2017 Jul 22;5(4):490-492. Epub 2017 Jul 22.
    Universita degli Studi di Messina, Policlinico Universitario, Via Consolare Valeria, Messina, Sicilia 98125, Italy.
    Erythema ab igne (EAI) represents the stereotype of a modern technology induced disease. Originally produced by repeated exposure of the skin to a heat source, more often because of habits related to the job or personal activities, this condition now tends to occur more frequently, being associated with a variety of modern instruments. The aim of our report is to discuss this strange medical condition with a focus on clinical features, possible confounding differential diagnoses and recommendations for prevention. Read More

    Well-differentiated inflammatory liposarcoma with metastasis in a 6-y-old cat.
    J Vet Diagn Invest 2017 Nov 6;29(6):896-899. Epub 2017 Aug 6.
    Departments of Veterinary Clinical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI (Alvarez, Shaffer).
    Liposarcomas are rare malignant tumors showing adipocytic differentiation. We report a well-differentiated liposarcoma in a 6-y-old, male neutered cat with a prominent inflammatory component and metastatic spread to the lungs. The patient was initially presented because of fever, lethargy, and a firm subcutaneous inguinal mass. Read More

    An Atypical Presentation of Chronic Atrophic Gastritis: Hemolytic Anemia and Mesenteric Panniculitis.
    Case Rep Hematol 2017 3;2017:5498034. Epub 2017 Jul 3.
    Albert Einstein Medical Center, Philadelphia, PA, USA.
    Microangiopathic hemolytic anemia (MAHA) requires an aggressive approach since primary thrombotic microangiopathy syndromes such as thrombotic thrombocytopenic purpura (TTP) can progress rapidly to a fatal outcome. Differential diagnosis can be challenging even for an experienced hematologist. We present a case of a 52-year-old male who presented with symptoms of mesenteric panniculitis and showed signs of MAHA. Read More

    Low-dose G-CSF improves fat graft retention by mobilizing endogenous stem cells and inducing angiogenesis, whereas high-dose G-CSF inhibits adipogenesis with prolonged inflammation and severe fibrosis.
    Biochem Biophys Res Commun 2017 Sep 26;491(3):662-667. Epub 2017 Jul 26.
    Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, Guang Zhou, Guang Dong, PR China. Electronic address:
    Background: Hematopoietic stem cells (HSCs) promote fat graft survival by modulating its revascularization. The authors hypothesize that mobilization of HSCs by G-CSF will improve fat graft survival. Hence, we evaluated the effect of different doses of G-CSF on fat grafting. Read More

    MYCOBACTERIUM INTRACELLULARE INFECTION CAUSING A RETROPERITONEAL MASS IN A BINTURONG (ARCTICTIS BINTURONG).
    J Zoo Wildl Med 2017 Jun;48(2):544-548
    A 19-yr-old castrated male binturong ( Arctictis binturong ) with a history of recurrent pyogranulomatous panniculitis, lymphangitis, and dermatitis was presented for evaluation of hyporexia and tenesmus. A large caudal abdominal mass was palpated on physical examination. On ultrasound, the mass encircled and obstructed the left ureter, resulting in hydroureter and hydronephrosis. Read More

    [Paniculitis as manifestation of prolonged febrile syndrome: Case report].
    Rev Chil Pediatr 2017 Jun;88(3):398-403
    Departamento Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
    Fever of unknown origin (FUO) is defined as fever over 7 to 10 days without a diagnosis despite a complete initial study. The most frequent causes are infections, autoimmune and tumors. Even though most cases are self-limited there is a minority that has an underlying etiology with an ominous forecast, encouraging a systematized study. Read More

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