4,443 results match your criteria Cold Panniculitis


The mesenteric panniculitis: a truly idiopathic disease?

Minerva Gastroenterol Dietol 2019 Feb 12. Epub 2019 Feb 12.

Department of Radiology, San Paolo Hospital, Milan, Italy.

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http://dx.doi.org/10.23736/S1121-421X.19.02564-9DOI Listing
February 2019

Mesenteric Panniculitis in Sjögren's Syndrome: A New Systemic Manifestation to Consider?

Eur J Case Rep Intern Med 2018 24;5(4):000788. Epub 2018 Apr 24.

Department of Internal Medicine A, Coimbra Hospital and University Center, Coimbra, Portugal.

The association between mesenteric panniculitis and Sjögren's syndrome, although rare, is starting to be recognized. Usually, mesenteric panniculitis is symptomatic, presenting with either general or gastrointestinal symptoms. Sjögren's syndrome is an autoimmune disease that typically affects secretory glands, but may have serious systemic involvement. Read More

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http://dx.doi.org/10.12890/2018_000788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346754PMC

Neutrophilic Panniculitis in a child with MYSM1 deficiency.

Pediatr Dermatol 2019 Feb 12. Epub 2019 Feb 12.

Paediatric Haematology Unit, Mubarak Al-Kabeer Hospital, Kuwait.

Neutrophilic panniculitis (NP) with myelodysplasia has been described in adults but not in children. We report a case of NP associated with myelodysplasia in a child with MYSM1 deficiency, a newly described syndrome with primary immunodeficiency (PI), bone marrow failure, and developmental aberrations. Read More

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http://dx.doi.org/10.1111/pde.13757DOI Listing
February 2019

Pediatric Subcutaneous Panniculitis-like T-Cell Lymphoma With Hemophagocytosis Showing Complete Resolution With the BFM90 Protocol: Case Report and Review of Literature.

J Pediatr Hematol Oncol 2019 Feb 5. Epub 2019 Feb 5.

Clinical Haematology and Bone Marrow Transplantation, Christian Medical College, Ludhiana, Punjab.

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a distinct subtype of peripheral T-cell lymphoma associated with aggressive clinical behavior. Since its original description, it has continued to be a rare disease, and <200 cases have been reported in literature. We report an 11-year-old boy who presented with SPTCL and hemophagocytic lymphohistiocytosis (HLH) and responded to high-dose multiagent chemotherapy. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001434DOI Listing
February 2019
4 Reads

Histoplasma panniculitis in a patient with systemic lupus erythematosus.

An Bras Dermatol 2019 Jan-Feb;94(1):96-98

Department of Infectious Diseases, Hospital Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Histoplasmosis usually presents primarily as lung infection. Occasionally, mainly in immunocompromised hosts, it can spread and cause systemic manifestations. Skin lesions have been reported in 10 to 15 percent of cases of disseminated histoplasmosis, and panniculitis has been described as an unusual form of presentation in affected patients. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20197636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360956PMC
September 2017
2 Reads

Alpha-1 Antitrypsin Substitution for Extrapulmonary Conditions in Alpha-1 Antitrypsin Deficient Patients.

Chronic Obstr Pulm Dis 2018 Sep 19;5(4):267-276. Epub 2018 Sep 19.

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder which most commonly manifests as pulmonary emphysema. Accordingly, alpha-1 antitrypsin (AAT) augmentation therapy aims to reduce the progression of emphysema, as achieved by life-long weekly slow-drip infusions of plasma-derived affinity-purified human AAT. However, not all AATD patients will receive this therapy, due to either lack of medical coverage or low patient compliance. Read More

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http://dx.doi.org/10.15326/jcopdf.5.4.2017.0161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361480PMC
September 2018
2 Reads

Panniculitis in rheumatology: features of course and outcomes.

Ter Arkh 2018 May;90(5):55-60

V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia.

Aim: The study of the course and outcomes of panniculitis (PN) in modern rheumatology practice.

Materials And Methods: We observed 209 patients (pts) (f-185, m-24 in age 17 to 80 years) with the input diagnosis "Erythema nodosum? Undifferentiated panniculitis?" and duration of illness in from 1 week to 25 years, observed in V.A. Read More

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http://dx.doi.org/10.26442/terarkh201890555-60DOI Listing
May 2018
1 Read

Breast involvement in mixed connective tissue disease.

Radiol Case Rep 2019 Apr 17;14(4):430-435. Epub 2019 Jan 17.

Department of Pathology, Mount Sinai Downtown Union Square. 10 Union Square East, NY 10003, New York, USA.

To date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors' knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient with mixed connective tissue disease with coarse sheet-like calcifications on mammography bilaterally, which increased over time corresponding to rise in levels of anti-dsDNA. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348285PMC
April 2019
1 Read

[Immunoglobulin G4 Unrelated Idiopathic Mesenteric Sclerosis].

Korean J Gastroenterol 2019 Jan;73(1):50-55

Division of Gastroenterology, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

Sclerosing mesenteritis is a rare benign disease with a prevalence of 0.16-3.4% and is characterized by chronic nonspecific inflammation and extensive fibrosis in the adipose tissue of the mesentery although the exact pathogenesis is still elusive. Read More

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http://dx.doi.org/10.4166/kjg.2019.73.1.50DOI Listing
January 2019

Subcutaneous panniculitis-like T-cell lymphoma responsive to combination therapy with methotrexate and corticosteroids.

Dermatol Online J 2018 Sep 15;24(9). Epub 2018 Sep 15.

Department of Dermatology, Oregon Health & Science University, Portland, Oregon.

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare condition that falls underneath the umbrella of primary cutaneous T-cell lymphomas (CTCLs). SPTCL can be very difficult to diagnose as it may mimic other subtypes of CTCL, such as γ/δ T-cell lymphoma (TCL), or other forms of panniculitis. Confirmation of diagnosis often requires immunohistochemical analysis and is essential for proper prognosis and therapeutic management. Read More

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September 2018
5 Reads

Efficacy of baricitinib in the treatment of chilblains associated with the type I interferonopathy Aicardi-Goutières syndrome.

Arthritis Rheumatol 2019 Jan 22. Epub 2019 Jan 22.

Department of Immunology.

Aicardi-Goutières syndrome (AGS) is a rare early-onset auto-inflammatory disease characterized by basal ganglia calcification, chronic cerebrospinal fluid (CSF) lymphocytosis, and elevated type I interferon (IFN) levels in the CSF (1, 2). Typical clinical manifestations include developmental delay, intellectual impairment, chilblain, panniculitis, glaucoma, and autoimmunity overlapping with systemic lupus erythematosus (SLE) This article is protected by copyright. All rights reserved. Read More

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http://doi.wiley.com/10.1002/art.40805
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http://dx.doi.org/10.1002/art.40805DOI Listing
January 2019
9 Reads

Panniculitis in childhood-onset systemic lupus erythematosus: a multicentric cohort study.

Adv Rheumatol 2019 Jan 18;59(1). Epub 2019 Jan 18.

Pediatric Rheumatology Unit, Children's Institute, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, Brazil.

Objective: To evaluate prevalence, clinical manifestations, laboratory abnormalities, treatment and outcome in a multicenter cohort of childhood-onset systemic lupus erythematosus (cSLE) patients with and without panniculitis.

Methods: Panniculitis was diagnosed due to painful subcutaneous nodules and/or plaques in deep dermis/subcutaneous tissues and lobular/mixed panniculitis with lymphocytic lobular inflammatory infiltrate in skin biopsy. Statistical analysis was performed using Bonferroni correction(p < 0. Read More

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https://advancesinrheumatology.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s42358-019-0049-9DOI Listing
January 2019
4 Reads

A case of erythema nodosum-like panniculitis induced by nivolumab in a patient with oesophageal cancer.

Australas J Dermatol 2019 Jan 17. Epub 2019 Jan 17.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/ajd.12970DOI Listing
January 2019
1 Read

Polymyositis with antisynthetase syndrome presented with lobular panniculitis: A case report.

Clin Case Rep 2019 Jan 22;7(1):128-130. Epub 2018 Nov 22.

Division of Dermatology, Faculty of Medicine Phramongkutklao Hospital Bangkok Thailand.

Panniculitis is rarely seen in polymyositis. To the best of our knowledge, we report the first case of panniculitis which precedes the antisynthetase syndrome. Read More

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http://dx.doi.org/10.1002/ccr3.1839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333058PMC
January 2019
1 Read

Mesenteric panniculitis: comparison of computed tomography findings in patients with and without malignancy.

Clin Exp Gastroenterol 2019 27;12:1-8. Epub 2018 Dec 27.

Department of Radiology, Jordan University of Science and Technology, King Abdullah University Hospital, Irbid, Jordan,

Purpose: The aim was to compare computed tomography (CT) findings between patients with mesenteric panniculitis (MP) with and without known malignancy.

Patients And Methods: We retrospectively analyzed 116 consecutive patients who were diagnosed with MP on the basis of CT findings and categorized them according to the absence (Group 1: 73 patients) or presence (Group 2: 43 patients) of malignancy. Patient age and sex, diameter, size, mass effect, location, and fat density of the MP mass, presence of a pseudocapsule and/or halo sign, and lymph node status were compared between the two groups. Read More

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http://dx.doi.org/10.2147/CEG.S182513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311320PMC
December 2018
1 Read

Post-erysipela panniculitis ossificans of the lower leg treated with pentoxifylline.

Dermatol Ther 2019 Jan 14:e12821. Epub 2019 Jan 14.

Department of Clinical-Surgical, Diagnostic, and Pediatric Science, Institute of Dermatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

We report the case of a female patient who developed a firm, wooden-like, nonpitting edema of the left lower leg after a dermo-hypodermitis. The clinical picture was accompanied by intense pain, strongly impacting the patient's quality of life. A soft-tissue ultrasound demonstrated several millimetric hyperechoic linear lesions whose histopathological examination was conclusive for panniculitis ossificans. Read More

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http://doi.wiley.com/10.1111/dth.12821
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http://dx.doi.org/10.1111/dth.12821DOI Listing
January 2019
8 Reads

Familial lupus panniculitis: two cases, same diagnosis, what evolution?

G Ital Dermatol Venereol 2019 Jan 9. Epub 2019 Jan 9.

Dermatological Unit, Department of Clinical and Molecular Sciences, Polytehnic Marche University, Ancona, Italy.

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http://dx.doi.org/10.23736/S0392-0488.18.06151-5DOI Listing
January 2019

Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction.

Dermatol Res Pract 2018 29;2018:5276528. Epub 2018 Nov 29.

Department of Physiotherapy, Federal University of São Carlos, São Carlos, Brazil.

Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Read More

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http://dx.doi.org/10.1155/2018/5276528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304526PMC
November 2018
2 Reads

Equestrian cold panniculitis in a cold-storage-room worker.

J Dermatol 2019 Jan 10. Epub 2019 Jan 10.

Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://doi.wiley.com/10.1111/1346-8138.14772
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http://dx.doi.org/10.1111/1346-8138.14772DOI Listing
January 2019
5 Reads

Superficial and Deep Cutaneous Involvement by RAS-Associated Autoimmunne Leukoproliferative Disease (RALD Cutis): A Histologic Mimicker of Histiocytoid Sweet Syndrome.

Am J Dermatopathol 2018 Dec 26. Epub 2018 Dec 26.

Department of Pathology, Florida Hospital Orlando, Orlando, FL.

RAS-associated autoimmune leukoproliferative disease (RALD) is a recently described noninfectious and nonmalignant clinical syndrome characterized by autoimmune disorders, massive splenomegaly, modest lymphadenopathy, and monocytosis. On the molecular level, RALD is defined by somatic mutations of either NRAS or KRAS gene in a subset of hematopoietic cells. To date, there is a dearth of well-documented histopathologic description of cutaneous involvement by RALD in the literature. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001332DOI Listing
December 2018
3 Reads

Utility of CD123 immunohistochemistry in differentiating lupus erythematosus from cutaneous T-cell lymphoma.

Histopathology 2018 Dec 31. Epub 2018 Dec 31.

Department of Pathology, University of Michigan, Ann Arbor, MI.

Aims: Histopathologic overlap between lupus erythematosus and certain types of cutaneous T-cell lymphoma (CTCL) is well documented. CD123+ plasmacytoid dendritic cells (PDCs) are typically increased in lupus erythematosus, but have not been well studied in CTCL. We aimed to compare CD123 immunostaining and histopathologic features in these conditions. Read More

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http://dx.doi.org/10.1111/his.13817DOI Listing
December 2018
1 Read

Rare T-Cell Subtypes.

Cancer Treat Res 2019 ;176:195-224

Department of Haematology, Peter MacCallum Cancer Centre, Melbourne, Australia.

There are a number of rare T-cell lymphoma subtypes that may be encountered in clinical practice. In recent years, improved immunohistochemical techniques and molecular tumor profiling have permitted refinement of some of the diagnostic categories in this group, as well as the recognition of distinct conditions not previously well elucidated. In this chapter, we cover the diagnostic and clinical features of some of the more common of these conditions, including subcutaneous panniculitis-like T-cell lymphoma, cutaneous gamma-delta T-cell lymphoma, enteropathy-associated T-cell lymphoma, monomorphic epitheliotropic intestinal T-cell lymphoma, primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma, CD4-positive small/medium T-cell lymphoproliferative disorder, and acral CD8-positive T-cell lymphoma. Read More

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http://dx.doi.org/10.1007/978-3-319-99716-2_10DOI Listing
January 2019
1 Read

Weber-Christian disease: a case report.

Vnitr Lek 2018 ;64(10):961-965

Weber-Christian disease is a rare disease from the group of chronic fibrosing conditions characterized by inflamma-tion of the adipose tissue - panniculitis and fibrosing with frequent systemic manifestations. Etiopathogenesis of the disease is not fully known, participation of autoimmune mechanisms is anticipated. Here, we report a case of a patient with this rare disease, diagnosed after a long and demanding diagnostic process, including repeated lapa-rotomies. Read More

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January 2018
7 Reads

Development of Lobular Panniculitis Long After Completing the Personalized Peptide Vaccine Therapy.

Am J Case Rep 2018 Dec 27;19:1530-1535. Epub 2018 Dec 27.

Cancer Vaccine Center, Kurume University, Kurume, Fukuoka, Japan.

BACKGROUND Personalized peptide vaccine therapy is regarded as a well-tolerated, safe and effective immunotherapy for patients with advanced cancers. Herein we report an exceptional case of a patient with advanced pancreatic cancer who developed delayed lobular panniculitis at sites corresponding to vaccine injections. CASE REPORT A 64-year-old Japanese female visited our clinic due to thirst and polydipsia; she was diagnosed as having type 2 diabetes. Read More

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http://dx.doi.org/10.12659/AJCR.912418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322063PMC
December 2018
1 Read

Hashimoto's encephalopathy in a patient with septal panniculitis: a case report.

Reumatismo 2018 Dec 20;70(4):268-269. Epub 2018 Dec 20.

Clinica Reumatologica, Policlinico San Martino, Genova.

Hashimoto's encephalopathy (HE) is an autoimmune form of encephalopathy, associated with autoimmune thyroiditis. Its prevalence is estimated to be 2:100,000. HE is characterized by behavioral changes, mental confusion, dysarthria, ataxia, psychosis, paranoia, convulsions, hallucinations, headache and hyperthermia. Read More

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http://dx.doi.org/10.4081/reumatismo.2018.1090DOI Listing
December 2018

Pancreatic panniculitis and solid pseudopapillary tumor of the pancreas: A case report.

World J Clin Cases 2018 Dec;6(15):1036-1041

Department of Pancreatic Surgery, West China Hospital/West China School of Medicine, Sichuan University, Chengdu 610041, Sichuan Province, China.

Solid pseudopapillary tumor of the pancreas (SPTP), also known as solid and papillary epithelial neoplasm of the pancreas, is a rare pancreatic exocrine tumor that is difficult to diagnose before surgery. Pancreatic panniculitis is a rare type that occurs in less than 3% of all patients with pancreatic diseases. We here report a 19-year-old woman who presented with persistent left upper quadrant pain without obvious cause for 1 d. Read More

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http://www.wjgnet.com/2307-8960/full/v6/i15/1036.htm
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http://dx.doi.org/10.12998/wjcc.v6.i15.1036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288509PMC
December 2018
1 Read

Malignant masquerade sclerosing mesenteritis: A case report and review.

Int J Surg Case Rep 2018 3;53:265-268. Epub 2018 Nov 3.

Indraprastha Apollo Hospital Delhi, India.

Mesenteric panniculitis (MP), also known as sclerosing mesenteritis (SM), retractile mesenteritis or mesenteric lipodystrophy, is a rarely diagnosed inflammatory condition of unknown etiology that involves the mesenteric adipose tissue. We are presenting a case of sclerosing mesenteritis which presented us with features suggestive of malignant lesion and turned out to be benign one. An elderly gentleman of 68 years male presented to us with history of nonprogressive pain abdomen since 2 months associated with low grade fever and on and off constipation. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263015PMC
November 2018
5 Reads

Vasculitis in Systemic Autoinflammatory Diseases.

Front Pediatr 2018 3;6:377. Epub 2018 Dec 3.

Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Autoinflammatory diseases (AID) are diseases of the innate immune system, characterized by recurrent episodes of localized or systemic inflammation. Vasculitis may accompany AID. The causes of the association of vasculitis with monogenic AID are still debated. Read More

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http://dx.doi.org/10.3389/fped.2018.00377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287042PMC
December 2018
15 Reads

Clinical, Epidemiological, and Etiological Changes in Erythema Nodosum.

Isr Med Assoc J 2018 Dec;20(12):770-772

Department of Internal Medicine F, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Background: Erythema nodosum (EN) is the most common type of panniculitis, commonly secondary to infectious diseases.

Objectives: To elucidate the causative factors and the clinical presentation of patients with EN (2004-2014) and to compare their data to those reported in a previous study.

Methods: A retrospective study was conducted of all patients diagnosed with EN who were hospitalized at Soroka University Medical Center (2004-2014). Read More

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December 2018
4 Reads

Hematopoietic stem cell transplantation for subcutaneous panniculitis-like T-cell lymphoma: single center experience in an Asian population.

Int J Hematol 2019 Feb 13;109(2):187-196. Epub 2018 Dec 13.

Division of Hematology, Department of Medicine, Taipei Veterans General Hospital, No. 201, Sec 2, Shih-Pai Road, Taipei, 112, Taiwan.

Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is a rare form of cytotoxic T-cell lymphoma. It is believed that SPTL in patients without hemophagocytic syndrome (HPS) follows an indolent course; in contrast, SPTL in patients with HPS has been associated with unfavorable survival. To provide more clinical data on SPTL in Asian populations and to identify optimal therapeutic strategies for SPTL, we assessed the clinicopathological features and long-term follow-up data of 10 Taiwanese SPTL patients diagnosed at a single center. Read More

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http://dx.doi.org/10.1007/s12185-018-02568-9DOI Listing
February 2019
3 Reads
1.679 Impact Factor

Cutaneous T-cell lymphoma (CTCL), rare subtypes: five case presentations and review of the literature.

Chin Clin Oncol 2018 Nov 21. Epub 2018 Nov 21.

Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer and Weill Cornell Medical College, New York, NY, USA.

The vast majority of cutaneous T-cell lymphomas (CTCL) are encompassed by mycosis fungoides and CD30+ lymphoproliferative disorder (LPD), however rare distinct CTCLs have been defined. The current edition of the World Health Organization (WHO) includes 12 CTCL subtypes with discrete diagnosable clinical, histologic and phenotypic features. The rarest subtypes, i. Read More

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http://dx.doi.org/10.21037/cco.2018.11.01DOI Listing
November 2018
5 Reads

Nodular Panniculitis with Hemophagocytic Lymphohistiocytosis.

Chin Med J (Engl) 2018 Dec;131(23):2860-2861

Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

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http://dx.doi.org/10.4103/0366-6999.246077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278194PMC
December 2018

Diagnostic histochemistry in non-neoplastic skin diseases.

Semin Diagn Pathol 2018 Nov 16;35(6):390-398. Epub 2018 Oct 16.

PRW Laboratories, Charlottesville, VA, USA.

Non-neoplastic skin lesions comprise a sizable group of disorders with variable etiologies and clinical manifestations. They can be grouped into vesiculopustular dermatitides; spongiotic and psoriasiform diseases; lichenoid dermatitides; lymphoid infiltrates of the dermis; granulomatous processes; bullous disorders; vasculopathies; panniculitides; deposition disorders; and defects in maintenance of dermal connective tissue. The use of histochemical methods continues to be an indispensable adjunct to conventional microscopy in the further characterization of such lesions. Read More

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http://dx.doi.org/10.1053/j.semdp.2018.10.006DOI Listing
November 2018
4 Reads

Rare Cutaneous T-Cell Lymphomas.

Hematol Oncol Clin North Am 2019 Feb;33(1):135-148

Department of Dermatology, University of Pittsburgh, 3708 Fifth Avenue, 5th Floor, Suite 500.68, Pittsburgh, PA 15213, USA. Electronic address:

Rare lymphoma includes the entities that occur in less than 1% of cases of all lymphomas. Although the percentage is low, there are more than eight lymphomas classified as rare lymphomas. This article describes clinical presentation, diagnosis, prognosis, and management of the most common rare lymphomas, including primary cutaneous γδ T-cell lymphoma, primary cutaneous CD4 small/medium T-cell lymphoproliferative disorder, primary cutaneous acral CD8 T-cell lymphoma, primary cutaneous CD8 aggressive epidermotropic cytotoxic T-cell lymphoma, extranodal NK-/T-cell lymphoma, nasal type, and subcutaneous panniculitis-like T-cell lymphoma. Read More

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http://dx.doi.org/10.1016/j.hoc.2018.08.004DOI Listing
February 2019
1 Read

Nodular vasculitis associated with lung adenocarcinoma.

An Bras Dermatol 2018 Nov/Dec;93(6):887-889

Department of Dermatology and Venereology, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

Nodular vasculitis is an uncommon type of panniculitis. It was firstly associated to the infection by Mycobacterium tuberculosis and named erythema induratum of Bazin, however nowadays it has been associated with several other underlying disorders and it is better described as nodular vasculitis. Concerning its relationship with malignant conditions, there is only one reported case, in association with metastatic colon adenocarcinoma. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256222PMC
February 2019
2 Reads

New data in causes of autoinflammatory diseases.

Joint Bone Spine 2018 Nov 22. Epub 2018 Nov 22.

Centre national de référence des maladies auto-inflammatoires et de l'amylose inflammatoire (CEREMAIA), 94270 Le Kremlin-Bicêtre, France; Cellules souches, plasticité cellulaire, médecine régénératrice et immunothérapies, Inserm, Université de Montpellier, 34090 Montpellier, France; Département de génétique médicale, maladies rares et médecine personnalisée, CHU de Montpellier, 34295 Montpellier, France.

The spectrum of factors known to mediate autoinflammation has broadened recently to include not only interleukin-1 (IL-1) and interferon, but also abnormalities that impair NF-κB pathway negative regulation. The NF-κB pathway is activated upon contact of a ligand with tumor necrosis factor receptor 1 (TNFR1) and plays a pivotal role in triggering the inflammatory process by producing major cytokines such as IL-1, IL-6, and TNF. Negative regulation of the NF-κB pathway, which is essential to stop the inflammatory process, depends on the level of ubiquitination of the proteins associated with TNFR1 and of other intermediate compounds. Read More

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http://dx.doi.org/10.1016/j.jbspin.2018.11.003DOI Listing
November 2018
15 Reads

Tocilizumab treatment in refractory polyarteritis nodosa: a case report and review of the literature.

Rheumatol Int 2019 Feb 21;39(2):337-344. Epub 2018 Nov 21.

Asklepios Klinik Altona, Rheumatologie, Klinische Immunologie, Nephrologie, Paul-Ehrlich-Straße 1, 22763, Hamburg, Germany.

Polyarteritis nodosa (PAN) is a rare systemic vasculitis affecting multiple organs. Current standard treatment includes the use of glucocorticoids and cyclophosphamide. Unfortunately, some patients do not respond to this treatment and other therapeutic options are needed. Read More

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http://dx.doi.org/10.1007/s00296-018-4210-2DOI Listing
February 2019
15 Reads

Relapsed subcutaneous panniculitis-like T cell lymphoma evaluated by FDG PET/CT: A clinical case report.

Medicine (Baltimore) 2018 Nov;97(46):e12980

Department of Nuclear Medicine.

Rationale: Subcutaneous panniculitis-like T cell lymphoma (SPTCL) is a rare primary cutaneous T cell lymphomas expressing α/β T cell receptors that preferentially involves subcutis, and few reports have investigated the diagnosis of suspicious relapsed SPTCL using F-fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography/computed tomography (PET/CT).

Patient Concerns: A 15-year-old woman complaining of a growing painless subcutaneous mass on perinaeum recurred 2 months ago, suggestive of suspicious relapsed SPTCL, underwent FDG PET/CT for diagnosis and treatment follow-up.

Diagnosis: Based on the feature of FDG PET/CT images which revealed multiple increased FDG-avid subcutaneous adipose tissue lesions on the left upper arm, the left chest and perinaeum, involvement of bilateral inguinal lymph nodes, and the effective chemotherapy, she was diagnosed with relapsed SPTCL. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811160-0001
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http://dx.doi.org/10.1097/MD.0000000000012980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257464PMC
November 2018
13 Reads
5.723 Impact Factor

Author Correction: Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome.

Nat Genet 2019 Jan;51(1):196

Department of Human Genetics, McGill University, Montreal, Quebec, Canada.

In the version of this article originally published, the main-text sentence "In three patients of European ancestry, we identified the germline variant encoding p.Ile97Met in TIM-3, which was homozygous in two (P12 and P13) and heterozygous in one (P15) in the germline but with no TIM-3 plasma membrane expression in the tumor" misstated the identifiers of the two homozygous individuals, which should have been P13 and P14. The error has been corrected in the HTML, PDF and print versions of the paper. Read More

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http://dx.doi.org/10.1038/s41588-018-0304-8DOI Listing
January 2019
15 Reads

Vemurafenib-induced histiocytoid neutrophilic panniculitis simulating myeloid leukaemia cutis.

Cancer Biol Ther 2019 14;20(3):237-239. Epub 2018 Nov 14.

d Department of Pathology , Hospital Universitari General de Catalunya-QuirónSalud, Universitat Internacional de Catalunya , Sant Cugat del Vallés, Barcelona , Spain.

Neutrophilic panniculitis is an infrequent but characteristic adverse event under therapy with BRAF inhibitors (BRAFi). Since the approval of vemurafenib for treatment of metastatic melanoma in 2011, only two cases of neutrophilic panniculitis in malignancies other than melanoma have been published. Histiocytoid infiltrates of immature neutrophils resembling histiocytes or myelocytes have been reported in Sweet's syndrome and rarely in other neutrophilic dermatoses. Read More

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https://www.tandfonline.com/doi/full/10.1080/15384047.2018.1
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http://dx.doi.org/10.1080/15384047.2018.1529113DOI Listing
November 2018
10 Reads
3.072 Impact Factor

Immunoglobulin G4-related disease with recurrent uveitis and kidney tumor mimicking childhood polyarteritis nodosa: a rare case report.

Acta Reumatol Port 2018 Jul-Sep;43(3):226-229

Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

Introduction: Immunoglobulin G4-related disease (IgG4-RD) is an condition rarely reported in children. Additionally, IgG4-RD may rarely mimic vasculitis in adults and may infrequently present with uveitis. In our service, 6,198 patients were followed-up and only one (0. Read More

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November 2018
4 Reads

Lobular panniculitis associated with chikungunya fever: A case report.

IDCases 2018 29;14:e00462. Epub 2018 Oct 29.

Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.

Chikungunya fever is a mosquito-borne viral disease classically characterized by an acute onset of fever, arthralgia, and skin rash. In this article, we report the acute febrile illness of an adult female with arthropathy and morbilliform eruptions. The patient developed panniculitis lesions on both shins. Read More

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http://dx.doi.org/10.1016/j.idcr.2018.e00462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214869PMC
October 2018

A solitary presentation of panniculitis in a patient with a history of breast cancer.

Ann Med Surg (Lond) 2018 Dec 17;36:54-57. Epub 2018 Oct 17.

Tecnologico de Monterrey, Hospital San Jose, Servicio de Patologia, Mexico.

Introduction: Panniculits presents as an inflammation of the subcutaneous adipose tissue of the skin. In breast, panniculitis is very rare and is usually a manifestation of underlying inflammatory conditions. The typical presentation is palpable tender nodules, which in cases of breast panniculitis, triggers an extensive work up to exclude a malignancy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S20490801183021
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http://dx.doi.org/10.1016/j.amsu.2018.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206327PMC
December 2018
15 Reads

Sterile Pyogranulomatous Dermatitis and Panniculitis.

Vet Clin North Am Small Anim Pract 2019 Jan;49(1):27-36

Department of Clinical Sciences, James L. Voss Veterinary Teaching Hospital, 300 West Drake Road, Fort Collins, CO 80525, USA. Electronic address:

Canine sterile pyogranulomatous dermatitis and panniculitis is an infrequently described syndrome. No autoantigen, or exogenous antigen, inflammatory stimulus has been identified. This syndrome is characterized by pyogranulomatous nodules, plaques, and ulcers of variable extent and severity. Read More

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http://dx.doi.org/10.1016/j.cvsm.2018.08.003DOI Listing
January 2019
1 Read

Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome.

Nat Genet 2018 Dec 29;50(12):1650-1657. Epub 2018 Oct 29.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada.

Subcutaneous panniculitis-like T cell lymphoma (SPTCL), a non-Hodgkin lymphoma, can be associated with hemophagocytic lymphohistiocytosis (HLH), a life-threatening immune activation that adversely affects survival. T cell immunoglobulin mucin 3 (TIM-3) is a modulator of immune responses expressed on subgroups of T and innate immune cells. We identify in ~60% of SPTCL cases germline, loss-of-function, missense variants altering highly conserved residues of TIM-3, c. Read More

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http://dx.doi.org/10.1038/s41588-018-0251-4DOI Listing
December 2018
2 Reads

Pancreatitis panniculitis polyarthritis syndrome with multiple bone infarcts.

QJM 2019 Jan;112(1):43-44

Department of Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

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http://dx.doi.org/10.1093/qjmed/hcy244DOI Listing
January 2019

Clinicopathologic, immunophenotypic, and molecular analysis of subcutaneous panniculitis-like T-cell lymphoma: A retrospective study in a tertiary care center.

J Cutan Pathol 2019 Jan 20;46(1):44-51. Epub 2018 Nov 20.

Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTL) as strictly defined by World Health Organization-European Organization for Research and Treatment of Cancer classification is a rare cytotoxic α/β T-cell lymphoma, characterized by primary involvement of subcutaneous tissue mimicking panniculitis.

Objectives: To describe the clinicopathologic, immunophenotypic, and molecular features of SPTL.

Methods: A 10-year retrospective study of 18 patients diagnosed with SPTL was thoroughly reviewed according to clinicopathology, immunophenotype, and T-cell receptor (TCR) gene rearrangement. Read More

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http://dx.doi.org/10.1111/cup.13377DOI Listing
January 2019

Use of QuantiFERON-TB Gold to determine the aetiology of idiopathic erythema induratum: A case report.

SAGE Open Med Case Rep 2018 10;6:2050313X18804076. Epub 2018 Oct 10.

Toronto Regional Dermatology and Wound Healing Clinic, Mississauga, ON, Canada.

Although rare, erythema induratum is the most common entity presenting as lobular panniculitis with vasculitis. It is usually caused by a hypersensitivity reaction to , although other aetiologies have been reported. We present a case of a 73-year-old male with multiple recurring tender erythematous nodules on the backs of both calves and shins. Read More

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http://journals.sagepub.com/doi/10.1177/2050313X18804076
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http://dx.doi.org/10.1177/2050313X18804076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180361PMC
October 2018
7 Reads

[Diffuse cutaneous lesions].

Rev Med Interne 2018 Oct 14. Epub 2018 Oct 14.

Service de médecine interne et maladies systémiques, CHU Dijon Bourgogne, 14, rue Paul-Gaffarel, 21000 Dijon, France.

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https://linkinghub.elsevier.com/retrieve/pii/S02488663183071
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http://dx.doi.org/10.1016/j.revmed.2018.09.009DOI Listing
October 2018
3 Reads

Mesenteric Panniculitis With Lupus Demonstrated on 18F-FDG PET/CT.

Clin Nucl Med 2018 Dec;43(12):e479-e481

From the Department of Nuclear Medicine, Algemeen Ziekenhuis Sint-Jan Brugge-Oostende, Oostende, Belgium.

We describe the F-FDG PET/CT findings in a rare case of mesenteric panniculitis caused by systemic lupus. A previous CT had raised suspicion of a space-occupying lesion in the left hypochondrium in a context of aspecific constitutional symptoms and inflammatory parameters. The diagnosis of panniculitis was confirmed at laparoscopic biopsy directed by the PET findings. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002306DOI Listing
December 2018
15 Reads