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    Sclerosing mesenteritis: a systematic review of 192 cases.
    Clin J Gastroenterol 2017 Feb 14. Epub 2017 Feb 14.
    Gastroenterology Center of Connecticut, Clinical Instructor of Medicine, Yale University School of Medicine, Hamden, 06518, CT, USA.
    Introduction: Sclerosing mesenteritis includes a spectrum of inflammatory disorders involving the adipose tissue of the bowel mesentery.

    Aim: To perform a systematic review of previously reported cases of sclerosing mesenteritis (SM) to determine the epidemiology, risk factors, methods of diagnosis, treatment patterns and outcomes for this disease.

    Methods: Medline, PubMed, Google Scholar and Cochrane database were searched using keywords mesenteric panniculitis, retractile mesenteritis, mesenteric lipodystrophy and sclerosing mesenteritis. Read More

    Lipophagic Panniculitis of Childhood: A Case Report and Comprehensive Review of the Literature.
    Am J Dermatopathol 2017 Feb 10. Epub 2017 Feb 10.
    *Weill Cornell Medical College, New York, NY; and Departments of †Dermatology, and ‡Pathology and Laboratory Medicine, NYPH-Weill Cornell Medicine, New York, NY.
    Lipophagic panniculitis of childhood is a rare condition notable clinically for an inflammatory panniculitis followed by the development of permanent lipoatrophy. In this regard, the term lipoatrophic panniculitis has been used synonymously with lipophagic panniculitis. Additional designations include lipophagic lipoatrophic panniculitis and annular lipoatrophic panniculitis of the ankles. Read More

    [An analysis of clinical characteristics of twelve cases of mesenteric panniculitis].
    Zhonghua Nei Ke Za Zhi 2017 Feb;56(2):112-115
    Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
    Objective: Mesenteric panniculitis is an idiopathic, uncommon disease involving the adipose tissue of mesentery. The etiology, diagnosis and treatment are still unnoticed. We thus reported a case series to improve the understanding of this rare disorder. Read More

    Pancreatitis, panniculitis and polyarthritis (PPP-) syndrome caused by post-pancreatitis pseudocyst with mesenteric fistula. Diagnosis and successful surgical treatment. Case report and review of literature.
    Int J Surg Case Rep 2017 Jan 18;31:170-175. Epub 2017 Jan 18.
    University Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Electronic address:
    Introduction: Pancreatitis, panniculitis and polyarthritis syndrome is a very rare extra-pancreatic complication of pancreatic diseases.

    Presentation Of Case: While in most cases this syndrome is caused by acute or chronic pancreatitis, we report a case of a 62-year-old man presenting with extensive intraosseous fat necrosis, polyarthritis and panniculitis caused by a post-pancreatitis pseudocyst with a fistula to the superior mesenteric vein and extremely high blood levels of lipase. This became symptomatic 2. Read More

    [Pancreatic Panniculitis in Patients with Chronic Pancreatitis: Case Report and Review of Literature].
    Korean J Gastroenterol 2017 Jan;69(1):83-86
    Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
    Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease. It has been postulated that pancreatic panniculitis is caused by the systemic activity of pancreatic enzymes that lead to microcirculatory disturbances. We report a 41-year-old heavy alcoholic woman with pancreatic panniculitis that coexisted with acute and chronic pancreatitis. Read More

    Panniculitis: A summary.
    Semin Diagn Pathol 2016 Dec 27. Epub 2016 Dec 27.
    Section of Dermatopathology,Dermatopathology, Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, Charlottesville, VA, USA. Electronic address:
    The diagnosis of panniculitis is felt to be a confusing topic by some pathologists. This summarical article presents inflammatory diseases of the subcutis in a systematic fashion, based on whether they are centered on fibrovascular septa or the adipose lobules, and whether morphologic vasculitis is present or not. Septocentric, non-vasculitis disorders include erythema nodosum, panniculitis that follows the use of "biological" therapeutic agents, lipodermatosclerosis, post-irradiation panniculitis, morphea profunda, and necrobiosis lipodica profunda. Read More

    Subcutaneous panniculitis-like T-cell lymphoma.
    Proc (Bayl Univ Med Cent) 2017 Jan;30(1):76-77
    Departments of Medical Oncology (Sugeeth, Narayanan) and Pathology (Jayasudha, Nair), Regional Cancer Centre, Trivandrum 695011, India.
    Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare form of skin lymphoma that is localized primarily to the subcutaneous adipose tissue without involvement of the lymph nodes. Clinically, the skin lesions mimic lipomas, while histologically they resemble panniculitis. We report a case of a young woman with SPTCL. Read More

    Clinical characteristics, differential diagnosis, and treatment outcome of subcutaneous panniculitis-like T-cell lymphoma: a literature review of published Japanese cases.
    Eur J Dermatol 2017 Feb;27(1):34-41
    Department of Dermatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
    Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare subtype of non-Hodgkin lymphoma that shows phenotypic features of cytotoxic T cells and preferentially involves subcutaneous tissue. SPTCL is believed to show an indolent clinical course, unless patients develop haemophagocytic syndrome. Various reported therapies include corticosteroids, immunosuppressive drugs, and chemotherapies. Read More

    Clinical significance of mesenteric panniculitis-like abnormalities on abdominal computerized tomography in patients with malignant neoplasms.
    World J Gastroenterol 2016 Dec;22(48):10601-10608
    Eli D Ehrenpreis, Grigory Roginsky, University of Chicago, Center for the Study of Complex Diseases, Gastroenterology, NorthShore University HealthSystem, Highland Park Hospital, Highland Park, IL 60035, United States.
    Aim: To clarify the association of malignancy with mesenteric panniculitis-like changes on computed tomography (CT).

    Methods: All abdominal CT scans performed at NorthShore University HealthSystem showing mesenteric panniculitis from January 2005 to August 2010 were identified in the Radnet (RadNet Corporation, Los Angeles, CA) database. Patients with a new or known diagnosis of a malignancy were included for this analysis. Read More

    Subcutaneous panniculitis-like T-cell lymphoma with haemophagocytic syndrome during tocilizumab therapy for juvenile idiopathic arthritis.
    Clin Exp Rheumatol 2017 Jan-Feb;35(1):174. Epub 2017 Jan 5.
    Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
    ****************************************************************************. Read More

    Decreased adipose tissue zinc content is associated with metabolic parameters in high fat fed Wistar rats.
    Acta Sci Pol Technol Aliment 2016 Jan-Mar;15(1):99-105
    Department of Biochemistry, Orenburg State Medical University, Orenburg, Russia.
    Background: Limited data on adipose tissue zinc content in obesity exist. At the same time, the association between adipose tissue zinc content and metabolic parameters in dietary-induced obesity is poorly studied. Therefore, the primary objective of this study is to assess adipose tissue zinc content and its association  with morphometric parameters, adipokine spectrum, proinflammatory cytokines, and apolipoprotein profile in high fat fed Wistar rats. Read More

    [A rare cause of severe panniculitis].
    Z Rheumatol 2017 Jan 5. Epub 2017 Jan 5.
    ACURA-Rheumazentrum Baden-Baden, Rotenbachtalstr. 5, 76530, Baden-Baden, Deutschland.
    A 58-year-old patient presented with a severe, episodic panniculitis of the upper legs. Necrosis of the fatty tissue and a suspected superinfection led to amputation of one leg. The panniculitis was caused by a hereditary deficiency of alpha-1 antitrypsin (AAT) due to a ZZ mutation of the AAT gene. Read More

    Occurrence of ticks in the subcutaneous tissue of red foxes, Vulpes vulpes in Czech Republic and Romania.
    Ticks Tick Borne Dis 2017 Feb 9;8(2):309-312. Epub 2016 Dec 9.
    Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Calea Mănăștur 3-5, Cluj-Napoca, 400372, Romania.
    An extensive survey of parasites in red foxes (Vulpes vulpes) was independently conducted in Romania and the Czech Republic. Carcasses were examined by necropsy, and small, dark nodules apparently containing ticks were noticed in the subcutaneous tissue of several foxes. Histopathological examination was performed using hematoxylin and eosin (HE) staining. Read More

    Inflammatory Skin Conditions Associated With Radiotherapy.
    Actas Dermosifiliogr 2016 Dec 20. Epub 2016 Dec 20.
    Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
    Radiotherapy for cancer is used increasingly. Because skin cells undergo rapid turnover, the ionizing radiation of radiotherapy has collateral effects that are often expressed in inflammatory reactions. Some of these reactions-radiodermatitis and recall phenomenon, for example-are very familiar to dermatologists. Read More

    Methotrexate-induced panniculitis in a patient with rheumatoid arthritis.
    Acta Dermatovenerol Alp Pannonica Adriat 2016 Dec;25(4):79-81
    Pathology and Laboratory Medicine Department, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE.
    Methotrexate-induced accelerated nodulosis (MIAN) is not an uncommon adverse effect associated with the use of the methotrexate in rheumatoid arthritis. Limited case reports describe panniculitis as a pathological finding in this setting. A 31-year-old female with seropositive rheumatoid arthritis on methotrexate therapy presented with a 2-week history of sudden onset of painful infiltrated subcutaneous nodules on both forearms. Read More

    Redundant plantar skin folds.
    Rom J Morphol Embryol 2016 ;57(3):1085-1088
    Department of Rheumatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania;
    A 46-year-old female patient presented with photosensitivity, symmetric arthritis, episodic plantar pain and strikingly redundant plantar skin folds, likely due to lipoatrophy after recurrent episodes of plantar panniculitis. In this context, leukopenia with lymphopenia, thrombocytopenia and positive antinuclear antibodies were revelatory for systemic lupus erythematosus. However, a small cerebriform plantar collagenoma, along with discrete dysmorphic features with downslanting palpebral fissures and mild right ptosis, second and third syndactyly and a larger first right toe since childhood, and early-onset bilateral ovarian cystadenoma, suggested a minimal Proteus syndrome. Read More

    Subcutaneous panniculitis-like T-cell lymphoma with macrophage activation syndrome treated by cyclosporine and prednisolone.
    Indian Dermatol Online J 2016 Nov-Dec;7(6):529-532
    Consultant Dermatologist, Centre for Skin Diseases and Laser Treatment, Bhopal, Madhya Pradesh, India.
    Subcutaneous panniculitis-like T-cell lymphoma (SPTCL; α/β T-cell subtype) is a distinct variantof cutaneous T-cell lymphomas, which presents as inflammatory subcutaneous nodules. A 17-year-old male presented with recurrent fever with concomitant facial swelling, pedal edema, hepatosplenomegaly, and mildly tender subcutaneous plaques in generalized distribution along with patches of scarring alopecia on scalp. There were features of macrophage activation syndrome in the form of hemophagocytosis in the bone marrow, pancytopenia, high serum lactate dehydrogenase levels, low fibrinogen clotting activity, prolonged activated prothrombine time (aPTT), increased serum ferritin, hypoalbuminemia, and hypertriglyceridemia. Read More

    Cutaneous lymphomas with a panniculitic presentation.
    Semin Diagn Pathol 2016 Nov 29. Epub 2016 Nov 29.
    Dept. of Dermatology, B1-Q-93, Leiden University Center, PO Box 9600, 2300 RC Leiden, The Netherlands. Electronic address:
    Subcutaneous panniculitis-like T-cell lymphoma and primary cutaneous gamma/delta T-cell lymphoma are the two most common types of cutaneous T-cell lymphoma presenting with panniculitis-like lesions. In this article the characteristic clinical, histological and immunophenotypical features of these conditions are reviewed and criteria to differentiate these tumors from other benign and malignant lymphoproliferations presenting with panniculitis-like lesions are discussed. Read More

    Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome: MRI features of intraosseous fat necrosis involving the feet and knees.
    Skeletal Radiol 2017 Feb 7;46(2):279-285. Epub 2016 Dec 7.
    Department of Pathology, Inje University College of Medicine, Busan Paik Hospital, Busan, South Korea.
    Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome is extremely rare and presents as a triad of the three diseases. The patient usually presents with mild or absent abdominal symptoms. Here, we report on a case of a 66-year-old male who presented with pain and swelling in both legs and mild abdominal pain. Read More

    Lipofilling: A New Therapeutic Option for the Treatment of Lupus Panniculitis-Induced Atrophy.
    Case Rep Dermatol 2016 Sep-Dec;8(3):323-326. Epub 2016 Nov 15.
    Paris Diderot-Sorbonne Paris Cité University, Paris, France; Department of Dermatology, Saint Louis Hospital (AP-HP), Paris, France; INSERM Unit U1163, Institut Imagine, Necker-Enfants Malades Hospital, Paris, France.
    Lupus panniculitis is a rare manifestation of cutaneous lupus erythematosus, which may lead to major aesthetic sequelae with a severe impact on patients' quality of life. We report 2 cases supporting the short- and long-term efficacy and safety of lipofilling in the treatment of lupus panniculitis-induced atrophy. These observations pave the way for prospective, larger-scale studies in patients with scarring lupus panniculitis, provided that the autoimmune pathogenic process is in complete, stable remission. Read More

    Purulent lupus panniculitis unmasked by FDG-PET/CT scan: A case report.
    Medicine (Baltimore) 2016 Nov;95(48):e5478
    aDepartment of Internal Medicine bDepartment of Nuclear Medicine cDepartment of Intensive Care Medicine, Martini Hospital, Groningen, The Netherlands.
    Rationale: Lupus panniculitis (LP) is a unique variant of cutaneous lupus erythematosus. Clinical manifestations are typically mild and include erythema, nodules, and small ulcers. In certain cases, diagnosing LP may be challenging. Read More

    Minocycline successfully treats exaggerated granulomatous hypersensitivity reaction to Mw immunotherapy.
    Dermatol Ther 2016 Nov 28. Epub 2016 Nov 28.
    Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
    Mycobacterium W (Mw) vaccine has been found to be effective in the treatment of leprosy and warts. Despite increasing use of Mw immunotherapy, data on its safety is limited. We report a series of eight patients who developed persisting injection site granulomatous reaction following Mw immunotherapy and were successfully treated with minocycline. Read More

    Dermatologic Manifestations of Monogenic Autoinflammatory Diseases.
    Dermatol Clin 2017 Jan;35(1):21-38
    Translational Autoinflammatory Disease Studies, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Building 10, Room 6D-47B, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address:
    Autoinflammatory disorders are sterile inflammatory conditions characterized by episodes of early-onset fever, rash, and disease-specific patterns of organ inflammation. Gain-of-function mutations in innate danger-sensing pathways, including the inflammasomes and the nucleic acid sensing pathways, play critical roles in the pathogenesis of IL-1 and Type-I IFN-mediated disorders and point to an important role of excessive proinflammatory cytokine signaling, including interleukin (IL)-1b , Type-I interferons, IL-18, TNF and others in causing the organ specific immune dysregulation. The article discusses the concept of targeting proinflammatory cytokines and their signaling pathways with cytokine blocking treatments that have been life changing for some patients. Read More

    Isolated omental panniculitis in a child with abdominal pain: case report.
    Arch Argent Pediatr 2016 Dec;114(6):e425
    Department of Pediatric Surgery, Katip Celebi University Faculty of Medicine. Izmir, Turkey.
    Isolated omental panniculitis is a rare entity mostly seen in adults. It presents with the inflammation of the fatty tissue of the omentum. The symptoms may vary from local (e. Read More

    Alpha-1 Antitrypsin Deficiency: Current Perspective from Genetics to Diagnosis and Therapeutic Approaches.
    Curr Med Chem 2016 Nov 18. Epub 2016 Nov 18.
    U.O.C. of Geriatrics - Unit of Respiratory Pathophysiology and Thoracic Endoscopy, , Campus Bio Medico University and Teaching Hospital, Via Alvaro del Portillo 200, 00128 - Rome, Italy.
    Alpha-1 antitrypsin (A1AT) is a 52-kDa, acute phase glycoprotein encoded by the protease inhibitor (PI) locus, located on the long arm of chromosome 14 (14q31-32.3). Its structure is composed of a total of 7 exons, 4 coding (II, III, IV, and V) and 3 non-coding (Ia, Ib, and Ic). Read More

    Lenalidomide for refractory cutaneous manifestations of pediatric systemic lupus erythematosus.
    Lupus 2016 Nov 10. Epub 2016 Nov 10.
    Department of Pediatrics, Duke University Medical Center, Durham, USA.
    Objective: Cutaneous manifestations of pediatric systemic lupus erythematosus cause significant morbidity. Lenalidomide, a thalidomide analogue, has shown promise treating cutaneous lupus erythematosus in adults. Our objective was to evaluate lenalidomide's efficacy and safety in treating refractory cutaneous manifestations of pediatric systemic lupus erythematosus. Read More

    Linear Sclerodermoid Lupus Erythematosus Profundus in a Child.
    Am J Dermatopathol 2016 Dec;38(12):904-909
    *Ackerman Academy of Dermatopathology, New York, NY; †Department of Dermatology, Kasr Alainy Faculty of Medicine, Cairo University, Giza, Egypt; ‡Departments of Internal Medicine and Pathology and Laboratory Medicine, Texas A&M University Health Science Center, Dallas, TX; §Department of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ; and ¶Department of Dermatology, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY.
    Lupus erythematosus panniculitis, also known as lupus profundus, is a variant in the clinicopathological spectrum of lupus erythematosus (LE) affecting about 2%-3% of LE patients. A linear configuration of LE panniculitis has been reported rarely with rare reports describing the coexistence of different forms of cutaneous LE and localized morphea. In this study, the authors present a 9-year-old girl with linear arrangement of subcutaneous nodules on her left forearm. Read More

    Recent advances in understanding and treating COPD related to α1-antitrypsin deficiency.
    Expert Rev Respir Med 2016 Dec 4;10(12):1281-1294. Epub 2016 Nov 4.
    b Department of Medicine , Pediatrics Pennsylvania State University College of Medicine at Hershey Medical Center , Hershey , PA , USA.
    Introduction: Alpha-1-antitrypsin deficiency (AATD) is an orphan disease that predisposes individuals to COPD and liver disease. The following is a comprehensive review of AATD from epidemiology to treatment for physicians who treat COPD or asthma. Areas covered: In this comprehensive review of alpha-1-antitrypsin deficiency, we describe the historical perspective, genetics, epidemiology, clinical presentation and symptoms, screening and diagnosis, and treatments of the condition. Read More

    Inflammatory leg nodules: A clinical and investigational study.
    Natl Med J India 2016 May-Jun;29(3):141-145
    Department of Dermatology and Venereology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
    Background: Inflammatory leg nodules are a diagnostically challenging group of dermatoses with limited tools for diagnosis. Considerable overlapping patterns exist despite their distinct clinical and histological features. We attempted to understand if undertaking investigations and studying the clinical course and treatment response can help in differentiating these dermatoses. Read More

    Cohort study of mesenteric panniculitis and its relationship to malignancy.
    Br J Surg 2016 Nov 12;103(12):1727-1730. Epub 2016 Aug 12.
    Colorectal Unit, Department of Surgery, Christchurch Hospital, Christchurch, 8011, New Zealand.
    Background: Mesenteric panniculitis (MP) is a rare condition that historically has been associated with the presence of malignancy. Paraneoplastic phenomena in general regress with cure and in most cases with treatment of the cancer. This study was undertaken to determine whether MP regressed with cancer treatment and cure. Read More

    [Mesenteric panniculitis associated with acute pancreatitis: about a case].
    Pan Afr Med J 2016 8;24:206. Epub 2016 Jul 8.
    Service de Chirurgie Générale Hôpital Des FSI La Marsa, Tunisie.
    Mesenteric panniculitis is a nonspecific inflammation involving the mesentery. Its clinical presentation is variable depending on the stage of the disease. Clinical signs are usually pain but half of the patients remain asymptomatic. Read More

    Erythema Nodosum-Like Panniculitis as a False-Positive 18F-FDG PET/CT in Advanced Melanoma Treated With Dabrafenib and Trametinib.
    Clin Nucl Med 2017 Jan;42(1):44-46
    From the Departments of *Nuclear Medicine, and †Oncology, Marqués de Valdecilla University Hospital, Molecular Imaging Group (IDIVAL), University of Cantabria, Santander, Spain.
    We present a 35-year-old woman with left axillary mass. Histopathological analysis revealed metastatic infiltration for BRAF-mutant melanoma. F-FDG PET/CT showed bilateral axillary lymphadenopathy as well as bone and subcutaneous metastases. Read More

    Cold-associated perniosis of the thighs histopathologically mimicking lupus. Six observations.
    J Eur Acad Dermatol Venereol 2016 Sep 16. Epub 2016 Sep 16.
    Service de dermatologie, Hôpital Henri Mondor, Assistance Publique-Hôpitaux de Paris, Créteil, France.
    Background: Equestrian cold panniculitis has been described since 1980 in horse riders or in stable employees. Histological aspect is underdescribed.

    Patients And Methods: We describe clinical and histological features of six horse riding or stable employees patients presenting with upper lateral thigh lesions during the winter months between 2014 and 2016 in our dermatological department. Read More

    Nicolau syndrome and localized panniculitis: a report of dual diagnoses with an emphasis on morphea profunda-like changes following injection with glatiramer acetate.
    J Cutan Pathol 2016 Nov 8;43(11):1056-1061. Epub 2016 Sep 8.
    Department of Dermatology, Oregon Health and Sciences University, Portland, OR, USA.
    Glatiramer acetate, given as a 40 mg subcutaneous injection thrice weekly, was recently approved by the FDA based on data suggesting better compliance and a more favorable side effect profile compared to lower dose, daily dosing. The most commonly reported adverse events are transient injection site reactions involving redness and pain at the site; however, more pronounced panniculitis and lipoatrophy have also been reported. Here, we present the case of a 51-year-old female treated with higher dose glatiramer acetate who presented with a cutaneous injection site reaction consistent with Nicolau syndrome. Read More

    Cutaneous manifestations in inflammatory bowel disease: a single institutional study of non-neoplastic biopsies over 13 years.
    J Cutan Pathol 2016 Nov 26;43(11):946-955. Epub 2016 Aug 26.
    Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, USA.
    Background: Skin is commonly affected by extraintestinal manifestations of inflammatory bowel disease (IBD), but a controlled, systematic histopathologic analysis of cutaneous lesions is lacking.

    Methods: A total of 4147 classified IBD [Crohn disease (CD) or ulcerative colitis (UC); 2000-2013] resections were cross referenced with skin biopsies. Associated non-neoplastic skin biopsies were categorized by basic reaction pattern and neutrophilic vs. Read More

    Pancreatic disease, panniculitis, polyarthrtitis syndrome successfully treated with total pancreatectomy: Case report and literature review.
    Int J Surg Case Rep 2016 28;28:223-226. Epub 2016 Sep 28.
    Division of General Surgery, Sanchinarro Hospital, San Pablo University, Madrid, Spain.
    Introduction: Pancreatic disease can be complicated by extrabdominal manifestations such as panniculitis and polyarthritis. The symptomatic triad comprising pancreatic disease, panniculitis and polyarthritis is also known as PPP syndrome and is characterized by severe chronic sequels and high mortality rate. We describe a case of PPP syndrome successfully treated with spleen preserving total pancreatectomy; in addition we performed a literature review. Read More

    A Young Woman with Panniculitis and Cytopenia who Later Developed Coagulopathy.
    J Assoc Physicians India 2016 Feb;64(2):65-67
    Professor, Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh.
    A young woman presented with panniculitis, fever and blood cytopenias, later going on to develop hemophagocytic lymphohistiocytosis. Further evaluation revealed the presence of subcutaneous panniculitis like T-cell lymphoma (SPTCL). With this case we present an approach to panniculitis, a commonly encountered skin manifestation with a wide range of differentials. Read More

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