168,679 results match your criteria Cold Agglutinin Disease
Sleep 2018 Dec 12. Epub 2018 Dec 12.
Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA.
Sleep abnormalities are common among children with neurodevelopmental disorders. The human chr16p11.2 microdeletion is associated with a range of neurological and neurobehavioral abnormalities. Read More
Ann Bot 2018 Dec 12. Epub 2018 Dec 12.
Institute of Botany, The Czech Academy of Sciences, Průhonice, Czech Republic.
Background And Aims: Alpine cushion plants can initially facilitate other species during ecological succession, but later on can be negatively affected by their development, especially when beneficiaries possess traits allowing them to overrun their host. This can be reinforced by accelerated warming favouring competitively strong species over cold-adapted cushion specialists. However, little empirical research has addressed the trait-based mechanisms of these interactions. Read More
Cell Rep 2018 Dec;25(11):3215-3228.e9
Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA; School of Biomedical Sciences and Engineering, The University of Maine, Orono, ME 04469, USA; Tufts University School of Medicine, 145 Harrison Avenue, Boston, MA 02111, USA. Electronic address:
Molecular- and cellular-based therapies have the potential to reduce obesity-associated disease. In response to cold, beige adipocytes form in subcutaneous white adipose tissue and convert energy stored in metabolic substrates to heat, making them an attractive therapeutic target. We developed a robust method to generate a renewable source of human beige adipocytes from induced pluripotent stem cells (iPSCs). Read More
Korean J Intern Med 2018 Dec 13. Epub 2018 Dec 13.
Lung Research Institute of Hallym University College of Medicine, Chuncheon, Korea.
Background/aims: Inhaled corticosteroids (ICS) are a treatment of choice for eosinophilic airway diseases, but their efficacy for other causes of chronic cough is controversial.
Methods: We conducted a prospective observational study to determine the ICS efficacy and clinical predictors of response to ICS in patients with upper airway cough syndrome (UACS) or unexplained chronic cough (UCC). Sixty-eight patients with UACS and 33 patients with UCC (duration of cough ≥ 8 weeks) were treated with ICS: 250 µg of fluticasone propionate or 400 µg of budesonide twice a day at physician's discretion. Read More
PLoS One 2018 12;13(12):e0207936. Epub 2018 Dec 12.
Department of Biology, Stanford University, Stanford, California, United States of America.
Species are shifting their ranges due to climate change, many moving to cooler and higher locations. However, with elevation increase comes oxygen decline, potentially limiting a species' ability to track its environment depending on what mechanisms it has available to compensate for hypoxic stress. Pikas (Family Ochotonidae), cold-specialist small mammal species, are already undergoing elevational range shifts. Read More
PLoS One 2018 12;13(12):e0207765. Epub 2018 Dec 12.
Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, United States of America.
Mindfulness practices are increasingly being utilized as a method for cultivating well-being. The term mindfulness is often used as an umbrella for a variety of different practices and many mindfulness-based interventions (MBIs) contain multiple styles of practice. Despite the diversity of practices within MBIs, few studies have investigated whether constituent practices produce specific effects. Read More
Vector Borne Zoonotic Dis 2018 Dec 12. Epub 2018 Dec 12.
Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University , Harbin, PR China .
Bluetongue (BT) is a noncontagious disease affecting domestic and wild ruminants. Outbreaks of BT can cause serious economic losses. Although the causative agent, BT virus (BTV) is endemic in China, a comprehensive analysis has yet to be conducted examining the spatial distribution and risk factors of the virus throughout the Inner Mongolia province. Read More
J Water Health 2018 Dec;16(6):958-969
School of Architectural and Surveying & Mapping Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, Jiangxi, China E-mail:
Aerobic granular sludge (AGS) was preserved using an agar embedding method to maintain its stability. No obvious damage was imposed on the granular appearance during 30 days of cold and dry storage, but the granular microstructure had an uneven surface with a large number of holes. The results were consistent with the extinction of microbial communities and the monitored consumption of extracellular polymeric substances, in which granular specific oxygen utilization rate and mixed liquor volatile suspended solids/mixed liquor suspended solids ratio, respectively, decreased by 72. Read More
Mol Biotechnol 2018 Dec 11. Epub 2018 Dec 11.
Department of Biomedical Chemistry, Faculty of Chemistry, University of Gdańsk, ul. Wita Stwosza 63, 80-308, Gdańsk, Poland.
Nucleases are an important group of hydrolases that degrade nucleic acids, with broad spectrum of applications in science and industry. In this paper, we report the identification and characterization of the nuclease from extremely psychrophilic bacterium Psychromonas ingrahamii that grows exponentially at 5 °C, but may also grow at even lower temperatures (down to - 12 °C). The putative endonuclease I gene, identified in the genome of P. Read More
Sci Adv 2018 Dec 7;4(12):eaau4869. Epub 2018 Dec 7.
Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziądzka 5, PL-87-100 Toruń, Poland.
We report on the first Earth-scale quantum sensor network based on optical atomic clocks aimed at dark matter (DM) detection. Exploiting differences in the susceptibilities to the fine-structure constant of essential parts of an optical atomic clock, i.e. Read More
Front Cell Infect Microbiol 2018 27;8:416. Epub 2018 Nov 27.
Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
is a bacterium that not only survives, but also thrives, proliferates, and remains infective at cold-storage temperatures, making it an adept foodborne pathogen. We analyzed the differences in gene expression between IP32953 grown at 3 and 28°C to investigate which genes were significantly more expressed at low temperature at different phases of growth. We isolated and sequenced the RNA from six distinct corresponding growth points at both temperatures to also outline the expression patterns of the differentially expressed genes. Read More
Case Rep Hematol 2018 13;2018:7586719. Epub 2018 Nov 13.
Division of Hematology and Medical Oncology, Department of Medicine, Mount Sinai Beth Israel, Mount Sinai Hospital, New York, NY, USA.
Paroxysmal cold hemoglobinuria (PCH) is a rare form of cold autoimmune hemolytic anemia first discovered in the early 20th century in adults with tertiary syphilis. Today, it is more commonly seen in children as a life-threatening anemia during a viral upper respiratory tract infection (URI). Although respiratory syncytial virus (RSV) has previously been reported to cause PCH in a child, herein we present the first documented case in an adult. Read More
EPMA J 2018 Dec 12;9(4):387-391. Epub 2018 Nov 12.
Department of Ophthalmology, University of Basel, Mittlere Strasse 91, CH-4031 Basel, Switzerland.
Background: There are many risk factors contributing to glaucomatous optic neuropathy. Beside increased intraocular pressure, vascular factors play a prominent role, particularly low blood pressure (BP), and vascular dysregulation. Both of them are essential components of the Flammer syndrome. Read More
Infect Drug Resist 2018 26;11:2461-2469. Epub 2018 Nov 26.
Department of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China,
Purpose: causes serious infections globally, including invasive pneumococcal disease (IPD). We analyze clinical features of pediatric IPD cases identified in China and antibiotic susceptibility of isolated pneumococcal strains.
Methods: Confirmed pediatric IPD patients were prospectively recruited to the study. Read More
Neuropsychiatr Dis Treat 2018 26;14:3231-3240. Epub 2018 Nov 26.
Psychological Centre for Adolescents and Children, The Affiliated 102 Hospital of The Second Military Medical University of People's Liberation Army of China, Shanghai, China,
Objective: To explore the effect of repetitive transcranial magnetic stimulation (rTMS) combined with atomoxetine (ATX) in the treatment of attention-deficit hyperactivity disorder (ADHD).
Methods: Sixty-four patients with newly diagnosed ADHD were enrolled from January 2016 to October 2017 from Psychological Centre for Adolescents and Children at 102th Hospital of People's Liberation Army of China. These patients were randomly assigned to three groups according to treatment method: the rTMS group, the ATX group, and the rTMS+ ATX group. Read More
Clin Ophthalmol 2018 20;12:2377-2382. Epub 2018 Nov 20.
Department of Internal Medicine, Phramongkutklao Hospital, Bangkok, Thailand,
Purpose: Tetracaine is one of the most common eye drops that are used for analgesia in clinical practice. However, it causes ocular burning sensation when instilled. This study aimed to compare the effects of the cold and room temperature tetracaine on burning sensation. Read More
J Parasit Dis 2018 Dec 19;42(4):630-635. Epub 2018 Oct 19.
4Department of Zoology, Faculty of Science, Damanhour University, Damanhûr, 21634 Egypt.
Patients with chronic renal failure are more susceptible to infections due to acquired immunodeficiency caused by uremia. Parasitic infections are one of the significant causes of morbidity and mortality in those patients, So we aimed to assess the prevalence of spp. and other protozoan infections in patients undergoing hemodialysis in Qena Governorate, Upper Egypt. Read More
Sci Rep 2018 Dec 11;8(1):17771. Epub 2018 Dec 11.
King Abdullah University of Science and Technology (KAUST), Red Sea Research Center (RSRC), Thuwal, 23955-6900, Saudi Arabia.
Ocean warming with climate change is forcing marine organisms to shift their distributions polewards and phenology. In warm tropical seas, evolutionary adaptation by local species to warming will be crucial to avoid predicted desertification and reduction in diversity. However, little is known about the adaptation of phytoplankton in warm seas. Read More
J Clin Neurosci 2018 Dec 8. Epub 2018 Dec 8.
Department of Neurology, Kirikkale University, Faculty of Medicine, Yenişehir Mahallesi, Ankara Road 7.Km., Kırıkkale Üniversitesi Kampüsü, 71450 Yahşihan, Kırıkkale, Turkey. Electronic address:
Clinical diagnosis of carpal tunnel syndrome (CTS) is confirmed by nerve conduction studies (NCS). In some cases, NCS may be normal. We aimed to demonstrate changes of distal motor latency (DML) and nerve conduction velocity (NCV) pathology of demyelination in entrapment neuropathy with cold application in case of clinical CTS with normal NCS. Read More
BMC Genomics 2018 Dec 11;19(1):898. Epub 2018 Dec 11.
Biology Department, Concordia University, 7141, Sherbrooke, W. Montreal (Quebec), H4B 1R6, Canada.
Background: Members of the Early Salt Induced 3 (Esi3/RCI2/PMP3) gene family in plants have been shown to be induced in response to both biotic and abiotic stresses and to enhance stress tolerance in both transgenic plants and Saccharomyces cerevisiae. Esi3 was first identified as a salt stress induced gene in the salt tolerant wild wheat grass, Lophopyrum elongatum, and subsequently homologous genes in many other species were found to be members of the gene family. These include Arabidopsis thaliana and Oryza sativa where they are referred to as Rare Cold Inducible 2 (RCI2), and Zea mays where they are referred to as Plasma Membrane Protein 3 (PMP3). Read More
J Cardiol Cases 2013 Feb 8;7(2):e48-e50. Epub 2012 Dec 8.
Department of Second Section of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fuxing Street, Guishan Township, Taoyuan County 33305, Taiwan.
Loss of voice due to vocal cord paralysis, as in Ortner syndrome, is secondary to left recurrent laryngeal nerve palsy. Cardiovascular cause should be listed as a differential diagnosis of hoarseness and is incumbent upon the diagnostic physician to be familiar with the condition. A 56-year-old male presented to our emergency department with shortness of breath due to severe mitral regurgitation. Read More
J Plant Physiol 2018 Dec 4;232:188-199. Epub 2018 Dec 4.
Department of Plants and Crops, Ghent University, Coupure links 653, 9000 Gent, Belgium. Electronic address:
We studied metabolic adaptations to cold stress in roses and identified genes in the carbohydrate pathway during acclimation and deacclimation. A field experiment with four rose cultivars belonging to different USDA plant hardiness zones was set up in Melle, Belgium (51° 0' N, 3° 48' E). The more cold-hardy cultivars ('Dagmar Hastrup' and 'John Cabot') reached their lowest LT value in December, indicating a rapid acclimation after the first occurrence of frost. Read More
J Clin Apher 2018 Dec 8. Epub 2018 Dec 8.
Department of Clinical Hematology - Blood Bank and Hemostasis, Onassis Cardiac Surgery Center, Kallithea, Greece.
Background: Perioperative therapeutic plasma exchange in patients with cardiovascular diseases poses several challenges, including alterations in intravascular volume, serum electrolytes, the coagulation cascade, and drug pharmacokinetics.
Methods: This review article summarizes different indications of plasma exchange for patients requiring cardiac surgery based on reported case reports and case series.
Results: The most common reported indication is plasma exchange for the management of allosensitized cardiac transplant candidate patients in combination with immunosuppressive regimens, which increases the likelihood of obtaining a cross-match-negative allograft, improving post-transplant clinical outcome. Read More
J Small Anim Pract 2018 Dec 11. Epub 2018 Dec 11.
Clinic for Small Animal Surgery and Reproduction, Ludwig-Maximilians-University, Munich 80539, Germany.
Objectives: To compare the efficacy of polyhexanide, cold argon plasma and saline in reducing bacterial bio-burden in dog bite wounds.
Materials And Methods: Prospective blinded randomised clinical trial. Dogs were randomly assigned to one of the treatment groups by lottery and bacterial cultures obtained before and after treatment were compared. Read More
Evolution 2018 Dec 11. Epub 2018 Dec 11.
Division of Ecology and Evolution, Research School of Biology, The Australian National University, 0200, Canberra, ACT, Australia.
Testing hypotheses on the drivers of clade evolution and trait diversification provides insight into many aspects of evolutionary biology. Often, studies investigate only the intrinsic biological properties of organisms as the causes of diversity, however extrinsic properties of a clade's environment, particularly geological history, may also offer compelling explanations. The Andes are a young mountain chain known to have shaped many aspects of climate and diversity of South America. Read More
Biotechnol Prog 2018 Dec 8:e2764. Epub 2018 Dec 8.
Department of Chemical Engineering, 1280 Main Street West, McMaster University, Hamilton, Ontario, Canada, L8S 4L7.
Rolling circle amplification (RCA), polymerase chain reaction (PCR), and loop-mediated isothermal amplification (LAMP), are powerful tools that can be used for gene manipulation, pathogen detection, and infectious disease diagnostics. However, these techniques require trained personnel, as the pipetting steps involved can lead to contamination and, consequently, erroneous results. Furthermore, many of the reagents used in molecular biology are thermally labile and must be kept within a cold-chain. Read More
Int Endod J 2018 Dec 8. Epub 2018 Dec 8.
Miadent Oral and Dental Health Center, Ankara, Turkey.
Aim: to compare the incidence, intensity and prediction of postoperative pain after glide path preparation with manual, continuous rotary and a novel reciprocating glide path instrument.
Methodology: The study included 240 patients, which were treated by 4 specialists according to a planned treatment protocol. Following access cavity preparation and prior to glide path preparation, the subjects were randomly assigned to 1 of the 3 groups according to the glide path instrument by choosing a sealed envelope containing the group name: R-Pilot (VDW, Munich, Germany), ProGlider (Dentsply Sirona, Ballaigues, Switzerland) and stainless-steel K-files (Dentsply Sirona) (n = 80). Read More
Eur J Cancer Care (Engl) 2018 Dec 10:e12976. Epub 2018 Dec 10.
Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Lin-Ko, Taiwan.
The purpose of this study was to evaluate the longitudinal incidence, severity, pattern of changes or predictors of oxaliplatin-induced peripheral neuropathy (OXAIPN) in Taiwanese patients with colorectal cancer. A longitudinal repeated measures study design was employed, and 77 participants were recruited from the colorectal and oncology departments of two teaching medical centres in Taiwan. Physical examinations were performed, and self-reports regarding adverse impacts of OXAIPN and quality of life were obtained at five time points throughout 12 cycles of chemotherapy (C/T). Read More
J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.
Histology and Cell Biology Department, Faculty of Medicine, Minia University, Minia, Egypt.
Omega-3 fatty acids are gaining attention as a therapeutic agent of many diseases. Their protective effect in a variety of diseases has been demonstrated. To the best of our knowledge, this is the first study on omega-3 fatty acids related to acute cold-restraint stress (CRS) induced hepatic dysfunction in rats. Read More
J Pharm Pharmacol 2018 Dec 10. Epub 2018 Dec 10.
Department of Pharmacology, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Objectives: The role of nuclear factor-2 erythroid related factor-2 (Nrf2) activator, berberine (BBR), has been established in rat model of streptozotocin induced diabetic neuropathy. Around 30-40% of cancer patients, on paclitaxel (PTX) chemotherapy develop peripheral neuropathy. The present study was contemplated with the aim of establishing the neuropathy preventive role of BBR, in paclitaxel induced peripheral neuropathy model in rats. Read More
Environ Sci Pollut Res Int 2018 Dec 8. Epub 2018 Dec 8.
Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan, 250100, PR China.
In the present study, the performance of surface flow constructed wetlands (SFCWs) added with different dosage of biochar (group A 0%, group B 10%, group C 20%; v/v) was investigated, to evaluate the effect of biochar on nitrogen removal of a constructed wetland. No significant difference was observed in NH-N removal among three groups even during different seasons. Labile organic carbon released from biochar distinctly enhanced denitrification process, which improved NO-N removal efficiency by 4. Read More
Cogn Affect Behav Neurosci 2018 Dec 7. Epub 2018 Dec 7.
Dipartimento di Psicologia, Università di Bologna, Bologna, Italy.
The ventromedial prefrontal cortex (vmPFC) is known to play a key role in reward processing and decision making. However, its relative contribution to affect-rich ("hot") and affect-poor ("cold") decisions is not fully understood. Damage to vmPFC is associated with impaired performance on laboratory tasks of decision making under ambiguity and risk. Read More
Mol Biol Evol 2018 Dec 7. Epub 2018 Dec 7.
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, USA.
Meiotic recombination comprises crossovers and non-crossovers. Recombination, crossover in particular, shuffles mutations and impacts both the level of genetic polymorphism and the speed of adaptation. In many species, the recombination rate varies across the genome with hot- and cold-spots. Read More
Heliyon 2018 Dec 1;4(12):e00999. Epub 2018 Dec 1.
Research Laboratories in Sciences Applied to Food, Canadian Irradiation Center, INRS-Institut Armand-Frappier, Institute of Nutraceutical and Functional Foods, 531 Boulevard des Prairies, Laval, Québec, H7V 1B7, Canada.
Some pathogens might develop favorable global adaptation in response to certain stress treatments resulting in enhanced virulence and/or resistance to a different stress. β-lactam resistance, as well as and genes involved in this resistance, were studied to evaluate their possible role in O157:H7 () radioresistance. adapted to 25, 15 or 7 μg/mL of kanamycin or carbenicillin, were produced and treated with sensitization (0. Read More
Transplant Direct 2018 Nov 23;4(11):e400. Epub 2018 Oct 23.
Division of Organ Transplantation, Department of Surgery, UMass Memorial Medical Center, University of Massachusetts, Worcester, MA.
Background: It remains controversial if arterial perfusion in addition to portal vein perfusion during machine preservation improves liver graft quality. Comparative studies using both techniques are lacking. We studied the impact of using single or dual machine perfusion of donation after circulatory death rat livers. Read More
Plast Reconstr Surg Glob Open 2018 Oct 3;6(10):e1839. Epub 2018 Oct 3.
Division of Plastic Surgery, University of Alberta, Edmonton, Alberta, Canada.
The nose plays a critical role in olfaction, air filtration and humidification, and facial aesthetics. Most nasal amputations result from animal bites, human bites, and lacerations from glass. Successful replantation yields the best aesthetic and functional outcomes and is preferred compared with multistage nasal reconstruction. Read More
Front Microbiol 2018 26;9:2824. Epub 2018 Nov 26.
Department of Food Science, Faculty of Agriculture and Food Sciences, Institute of Nutrition and Functional Foods, Université Laval, Québec City, QC, Canada.
The aim of this study was to evaluate the impact of chitosan film, with bacteriocin divergicin 35 incorporate, on growth of in Cold smoked salmon. The simples of Cold-smoked wild salmon were inoculated with and treated with chitosan (100 kDa, 94.7% de-acetylated) and divergicin M35 was stored for 3 weeks at 4-8°C. Read More
Proteome Sci 2018 24;16:20. Epub 2018 Nov 24.
1Department of Bioresource Engineering, Macdonald Campus, McGill University, 21,111 Lakeshore Boulevard, Sainte-Anne-de-Bellevue, Quebec H9X 3V9 Canada.
Background: Abiotic stress reduces photosynthetic yield and plant growth, negatively impacting global crop production and is a major constraint faced by agriculture. However, the knowledge on the impact on plants under extremely high irradiance is limited. We present the first in-depth proteomics analysis of plants treated with a method developed by our research group to generate a light gradient using an extremely intense light. Read More
Trauma Case Rep 2018 Dec 27;18:42-45. Epub 2018 Nov 27.
Department of Orthopaedic and Traumatology, Penang General Hospital, Georgetown, Malaysia.
Open traumatic scapulothoracic dissociation is a rare and devastating injury. We are reporting a 21-year-old male factory worker who sustained a traumatic open scapulothoracic dissociation. His left arm was caught in conveyer belts resulting the arm, scapula, clavicle, and pectoral muscle torn from the body by tremendous traction force. Read More
J Transplant 2018 8;2018:9205083. Epub 2018 Nov 8.
Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada.
Background: Recent changes in the demographic of cardiac donors and recipients have modulated the rate and risk, associated with posttransplant diabetes mellitus (PTDM). We investigated the secular trends of the risk of PTDM at 1 year and 3 years after transplantation over 30 years and explored its effect on major outcomes.
Methods: Three hundred and three nondiabetic patients were followed for a minimum of 36 months, after a first cardiac transplantation performed between 1983 and 2011. Read More
PLoS One 2018 11;13(12):e0208721. Epub 2018 Dec 11.
Institute for Materials Discovery, University College London, London, United Kingdom.
The present work investigates the process of frosting formation on arched copper samples with different surface temperatures, calculated the thickness of the frost layer by using the scale method, and analyzed frost lodging, melting, and other phenomena that appeared during the frost-formation process. The results showed that the frosting process on an arched surface can be divided into ice-film formation, rapid growth of the frost layer, and stable growth of the frost layer. Meanwhile, the phenomena of frost-branch breakage, lodging, and melting were observed. Read More
PLoS One 2018 11;13(12):e0202375. Epub 2018 Dec 11.
Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry, Shaanxi Normal University, Xi'an, China.
Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs, which increasingly drawn researchers' attention in recent years as their importance in regulating gene expression at the transcriptional and post-transcriptional levels. With the development of high-throughput sequencing and bioinformatics, circRNAs have been widely analysed in animals, but the understanding of characteristics and function of circRNAs is limited in plants, especially in maize. Here, 3715 unique circRNAs were predicted in Zea mays systematically, and 8 of 12 circRNAs were validated by experiments. Read More
Front Microbiol 2018 23;9:2873. Epub 2018 Nov 23.
Geomicrobiology, GEOMAR Helmholtz Centre for Ocean Research Kiel, Kiel, Germany.
Deep-sea hydrothermal vents may provide one of the largest reservoirs on Earth for hydrogen-oxidizing microorganisms. Depending on the type of geological setting, hydrothermal environments can be considerably enriched in hydrogen (up to millimolar concentrations). As hot, reduced hydrothermal fluids ascend to the seafloor they mix with entrained cold, oxygenated seawater, forming thermal and chemical gradients along their fluid pathways. Read More
J Vis Exp 2018 Nov 20(141). Epub 2018 Nov 20.
Institute of Vegetables, Zhejiang Academy of Agricultural Sciences; State Key Lab Breeding Base for Sustainable Control of Plant Pest and Disease, Zhejiang Academy of Agricultural Sciences;
MicroRNAs (miRNAs) are endogenous small non-coding RNAs of about 20 - 24 nt, known to play important roles in plant development and adaptation. There is an accumulating evidence showing that the expressions of certain miRNAs are altered when grafting, an agricultural practice commonly used by farmers to improve crop tolerance to biotic and abiotic stresses. Bottle gourd is an inherently climate-resilient crop compared to many other major cucurbits, including watermelon, rendering it one of the most widely used rootstocks for the latter. Read More
Med Sci Sports Exerc 2018 Dec 5. Epub 2018 Dec 5.
Department of Kinesiology, Kansas State University, Manhattan, KS.
Introduction: the aim of the current investigation was to examine if dietary nitrate supplementation would improve vascular control in hypertensive post-menopausal women (PMW). We tested the hypotheses that acute dietary nitrate supplementation would 1) significantly decrease arterial blood pressure (BP) at rest and during exercise; 2) increase limb blood flow during steady-state exercise; and 3) improve functional sympatholysis during steady-state (SS) exercise.
Methods: ten hypertensive PMW underwent a randomized, double-blind placebo-controlled trial with a nitrate-rich (NR) or nitrate poor (NP) supplement. Read More
Int J Rehabil Res 2018 Dec 10. Epub 2018 Dec 10.
Istituti Clinici Scientifici Maugeri, IRCCS, Bioengineering Unit of Veruno Institute (NO) Italy.
The aim of this study was to analyse the Cold Intolerance Symptom Severity (CISS) questionnaire in its Italian validated version, using Rasch analysis, to gain insights for a possible refinement of the questionnaire. The CISS was administered to a convenience sample of 96 consecutively recruited outpatients with upper limb peripheral nerve injury. Data were analysed using Rasch analysis. Read More
Exp Anim 2018 Dec 10. Epub 2018 Dec 10.
School of Energy and Environment Engineering, Zhongyuan University of Technology.
Inhalation of pathogenic bacteria transported by particulate matter (PM) presents an important potential threat to human health. Therefore, the pulmonary toxicity in mice caused by Staphylococcus aureus (S. aureus) and PM as individual matter and mixtures was studied. Read More
Scand J Pain 2018 Dec 7. Epub 2018 Dec 7.
School of Psychology, Keele University, Keele, Staffordshire, UK.
Background and aims Prior research indicates that swearing increases pain tolerance and decreases pain perception in a cold pressor task. In two experiments, we extend this research by testing whether taboo hand gesticulations have a similar effect. Methods Study 1 focused on males and females who, across two trials, submerged an extended middle finger (taboo) and an extended index finger (control) in ice water until discomfort necessitated removal. Read More
J Endocrinol 2019 Feb;240(2):257-269
Naomi Berrie Diabetes Center, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Fat remodeling has been extensively explored through protein deacetylation, but not yet acetylation, as a viable therapeutic approach in the management of obesity and related metabolic disorders. Here, we investigated the functions of key acetyltransferases CBP/p300 in adipose remodeling and their physiological effects by generating adipose-specific deletion of CBP (Cbp-AKO), p300 (p300-AKO) and double-knockout (Cbp/p300-AKO) models. We demonstrated that Cbp-AKO exhibited marked brown remodeling of inguinal WAT (iWAT) but not epididymal WAT (eWAT) after cold exposure and that this pattern was exaggerated in diet-induced obesity (DIO). Read More
J Nucl Med 2018 Dec 7. Epub 2018 Dec 7.
Children's Hospital Boston, United States.
The purpose of this study was to assess image quality and quantitative brain PET across a multi-center consortium. All academic centers and children's hospitals in the Pediatric Brain Tumor Consortium (PBTC) scanned a phantom developed by the Society of Nuclear Medicine and Molecular Imaging Clinical Trials Network (SNMMI CTN) for the validation of brain PET studies associated with clinical trials. The phantom comprises 2 separate, fillable sections: a resolution/uniformity section and a clinical simulation section. Read More