Mol Omics 2021 Jun;17(3):454-463
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55902, USA. and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA and Center for Individualized Medicine, Mayo Clinic, Rochester, MN 55905, USA and Department of Biological Chemistry, Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Alzheimer's disease (AD) is the most common cause of dementia and is associated with serious neurologic sequelae resulting from neurodegenerative changes. Identification of markers of early-stage AD could be important for designing strategies to arrest the progression of the disease. The brain is rich in lipids because they are crucial for signal transduction and anchoring of membrane proteins. Read More