14,065 results match your criteria Cochrane Database of Systematic Reviews[Journal]


Systemic corticosteroids for the management of cancer-related breathlessness (dyspnoea) in adults.

Cochrane Database Syst Rev 2019 Feb 20;2:CD012704. Epub 2019 Feb 20.

School of Pharmacy, Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.

Background: Dyspnoea is a common symptom in advanced cancer, with a prevalence of up to 70% among patients at end of life. The cause of dyspnoea is often multifactorial, and may cause considerable psychological distress and suffering. Dyspnoea is often undertreated and good symptom control is less frequently achieved in people with dyspnoea than in people with other symptoms of advanced cancer, such as pain and nausea. Read More

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http://dx.doi.org/10.1002/14651858.CD012704.pub2DOI Listing
February 2019
1 Read

Competitions for smoking cessation.

Cochrane Database Syst Rev 2019 Feb 20;2:CD013272. Epub 2019 Feb 20.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: Competitions might encourage people to undertake and/or reinforce behaviour change, including smoking cessation. Competitions involve individuals or groups having the opportunity to win a prize following successful cessation, either through direct competition or by entry into a lottery or raffle.

Objectives: To determine whether competitions lead to higher long-term smoking quit rates. Read More

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http://dx.doi.org/10.1002/14651858.CD013272DOI Listing
February 2019

Interventions for primary vesicoureteric reflux.

Cochrane Database Syst Rev 2019 Feb 20;2:CD001532. Epub 2019 Feb 20.

Analytics Assist, NSW Ministry of Health, 73 Miller St, North Sydney, NSW, Australia, 2060.

Background: Vesicoureteric reflux (VUR) results in urine passing retrograde up the ureter. Urinary tract infections (UTI) associated with VUR have been considered a cause of permanent renal parenchymal damage in children with VUR. Management has been directed at preventing UTI by antibiotic prophylaxis and/or surgical correction of VUR. Read More

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http://dx.doi.org/10.1002/14651858.CD001532.pub5DOI Listing
February 2019

Effectiveness of provision of animal-source foods for supporting optimal growth and development in children 6 to 59 months of age.

Cochrane Database Syst Rev 2019 Feb 19;2:CD012818. Epub 2019 Feb 19.

Brown School/Institute for Public Health, Washington University in St. Louis, 1 Brookings Drive, St. Louis, Missouri, USA, 63130.

Background: Adequate nutrients early in life promote cognitive development and are critical for proper growth and functioning. The effect of individual nutrients consumed through food is often not the same as consuming the same nutrients in supplementary form due to 'food synergy', the biological and chemical interrelations that occur between nutrients. Animal-source foods, such as eggs, meat, fish, and dairy, are energy dense and contain multiple micronutrients and essential fatty acids with high bioavailability. Read More

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http://dx.doi.org/10.1002/14651858.CD012818.pub2DOI Listing
February 2019
1 Read

Surgical interventions for the prevention or treatment of lymphoedema after breast cancer treatment.

Cochrane Database Syst Rev 2019 Feb 19;2:CD011433. Epub 2019 Feb 19.

Department of Plastic Surgery, Helsinki University Hospital, PL 266, Helsinki, Finland, FIN-00029 HUS.

Background: Breast cancer is the most common type of cancer amongst women worldwide, and one distressing complication of breast cancer treatment is breast and upper-limb lymphoedema. There is uncertainty regarding the effectiveness of surgical interventions in both the prevention and management of lymphoedema affecting the arm after breast cancer treatment.

Objectives: 1. Read More

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http://doi.wiley.com/10.1002/14651858.CD011433.pub2
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http://dx.doi.org/10.1002/14651858.CD011433.pub2DOI Listing
February 2019
1 Read

Transcutaneous electrical nerve stimulation (TENS) for chronic pain - an overview of Cochrane Reviews.

Cochrane Database Syst Rev 2019 Feb 19;2:CD011890. Epub 2019 Feb 19.

School of Physiotherapy, The University of Notre Dame Australia, 19 Mouat Street (PO Box 1225), Fremantle, Western Australia, Australia, 6959.

Background: Chronic pain, considered to be pain lasting more than three months, is a common and often difficult to treat condition that can significantly impact upon function and quality of life. Treatment typically includes pharmacological and non-pharmacological approaches. Transcutaneous electrical nerve stimulation (TENS) is an adjunct non-pharmacological treatment commonly recommended by clinicians and often used by people with pain. Read More

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http://dx.doi.org/10.1002/14651858.CD011890.pub2DOI Listing
February 2019

Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer.

Cochrane Database Syst Rev 2019 Feb 18;2:CD012873. Epub 2019 Feb 18.

Medical Oncology Department, Concord Repatriation General Hospital, Concord, New South Wales, Australia, 2139.

Background: Anthracyclines and taxanes are chemotherapeutic agents widely used in a sequential regimen in the adjuvant and neoadjuvant treatment of early breast cancer to reduce the risk of cancer recurrence. Standard practice is to administer anthracycline-based chemotherapy followed by a taxane. Anthracyclines tend to be administered first as they were established before taxanes for treatment of early breast cancer. Read More

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http://dx.doi.org/10.1002/14651858.CD012873.pub2DOI Listing
February 2019
1 Read

Late erythropoiesis-stimulating agents to prevent red blood cell transfusion in preterm or low birth weight infants.

Cochrane Database Syst Rev 2019 Feb 15;2:CD004868. Epub 2019 Feb 15.

Neonatal Intensive Care Unit, Neocare Hospital, Mumbai Naka, Nashik, Maharashtra, India, 422002.

Background: Preterm infants have low plasma levels of erythropoietin (EPO), providing a rationale for the use of erythropoiesis-stimulating agents (ESAs) to prevent or treat anaemia. Darbepoetin (Darbe) and EPO are currently available ESAs.

Objectives: To assess the effectiveness and safety of late initiation of ESAs, between eight and 28 days after birth, in reducing the use of red blood cell (RBC) transfusions in preterm or low birth weight infants. Read More

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http://dx.doi.org/10.1002/14651858.CD004868.pub5DOI Listing
February 2019

Transcatheter arterial chemoembolisation followed by three-dimensional conformal radiotherapy versus transcatheter arterial chemoembolisation alone for primary hepatocellular carcinoma in adults.

Cochrane Database Syst Rev 2019 Feb 16;2:CD012244. Epub 2019 Feb 16.

Clinical Research Center, South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, 232 Waihuan Dong Road, Guangzhou, Guangdong, China, 510006.

Background: Hepatocellular carcinoma, also called malignant hepatoma, is a primary malignancy of the liver. Despite regular surveillance conducted in high-risk populations, most people with hepatocellular carcinoma are diagnosed at an advanced stage. Consequently, only a minority of people with the disease are suitable for surgical resection when diagnosed. Read More

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http://dx.doi.org/10.1002/14651858.CD012244.pub2DOI Listing
February 2019

Antibiotic treatment for newborns with congenital syphilis.

Cochrane Database Syst Rev 2019 Feb 15;2:CD012071. Epub 2019 Feb 15.

C/o Cochrane Pregnancy and Childbirth Group, Department of Women's and Children's Health, The University of Liverpool, First Floor, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, UK, L8 7SS.

Background: Congenital syphilis continues to be a substantial public health problem in many parts of the world. Since the first use of penicillin for the treatment of syphilis in 1943, which was a notable early success, it has remained the preferred and standard treatment including for congenital syphilis. However, the treatment of congenital syphilis is largely based on clinical experience and there is extremely limited evidence on the optimal dose or duration of administration of penicillin or the use of other antibiotics. Read More

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http://dx.doi.org/10.1002/14651858.CD012071.pub2DOI Listing
February 2019

Aquablation of the prostate for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.

Cochrane Database Syst Rev 2019 Feb 13;2:CD013143. Epub 2019 Feb 13.

Department of Urology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Korea, South.

Background: New, minimally invasive surgeries have emerged as alternatives to transurethral resection of the prostate (TURP) for the management of lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). Aquablation is a novel, minimally invasive, water-based therapy, combining image guidance and robotics for the removal of prostatic tissue.

Objectives: To assess the effects of Aquablation for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. Read More

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http://dx.doi.org/10.1002/14651858.CD013143.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373984PMC
February 2019

Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders.

Cochrane Database Syst Rev 2019 Feb 13;2:CD009824. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Melaka Manipal Medical College, Bukit Baru, Jalan Batu, Hampar, Melaka, Malaysia, 75150.

Background: Congenital bleeding disorders can cause obstetric haemorrhage during pregnancy, labour and following delivery. Desmopressin acetate (DDAVP) is found to be an effective drug which can reduce the risk of haemorrhage and can also stop bleeding in certain congenital bleeding disorders. Its use in pregnancy has been controversial. Read More

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http://dx.doi.org/10.1002/14651858.CD009824.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373982PMC
February 2019
1 Read

Calcium antagonists for acute ischemic stroke.

Cochrane Database Syst Rev 2019 Feb 13;2:CD001928. Epub 2019 Feb 13.

Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45, Changchun Street, Beijing, Beijing, China, 100053.

Background: The sudden loss of blood supply in ischemic stroke is associated with an increase of calcium ions within neurons. Inhibiting this increase could protect neurons and might reduce neurological impairment, disability, and handicap after stroke.

Objectives: To assess the effects of calcium antagonists for reducing the risk of death or dependency after acute ischemic stroke. Read More

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http://dx.doi.org/10.1002/14651858.CD001928.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373522PMC
February 2019
1 Read

Relapse prevention interventions for smoking cessation.

Cochrane Database Syst Rev 2019 Feb 13;2:CD003999. Epub 2019 Feb 13.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Background: A number of treatments can help smokers make a successful quit attempt, but many initially successful quitters relapse over time. Several interventions have been proposed to help prevent relapse.

Objectives: To assess whether specific interventions for relapse prevention reduce the proportion of recent quitters who return to smoking. Read More

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http://doi.wiley.com/10.1002/14651858.CD003999.pub5
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http://dx.doi.org/10.1002/14651858.CD003999.pub5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372978PMC
February 2019
4 Reads

Active versus expectant management for women in the third stage of labour.

Cochrane Database Syst Rev 2019 Feb 13;2:CD007412. Epub 2019 Feb 13.

School of Nursing and Midwifery, Trinity College Dublin, 24 D'Olier Street, Dublin, Ireland.

Background: Active management of the third stage of labour involves giving a prophylactic uterotonic, early cord clamping and controlled cord traction to deliver the placenta. With expectant management, signs of placental separation are awaited and the placenta is delivered spontaneously. Active management was introduced to try to reduce haemorrhage, a major contributor to maternal mortality in low-income countries. Read More

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http://dx.doi.org/10.1002/14651858.CD007412.pub5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372362PMC
February 2019
2 Reads

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders.

Cochrane Database Syst Rev 2019 Feb 12;2:CD010734. Epub 2019 Feb 12.

Office of the Chief Scientist, The George Institute for Global Health, University of New South Wales, Sydney, Australia.

Background: Iodine deficiency disorders (IDD) affect close to 1.9 billion people worldwide, and are a major public health concern in many countries. Among children, iodine deficiency is the main cause of potentially preventable deficits of central nervous system development and impairment of cognitive function, as well as goitre and hypothyroidism in people of all ages. Read More

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http://dx.doi.org/10.1002/14651858.CD010734.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370918PMC
February 2019
2 Reads

Nerve-sparing radical hysterectomy compared to standard radical hysterectomy for women with early stage cervical cancer (stage Ia2 to IIa).

Cochrane Database Syst Rev 2019 Feb 12;2:CD012828. Epub 2019 Feb 12.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, 123 Mitraparb Road, Amphur Muang, Khon Kaen, Thailand, 40002.

Background: Radical hysterectomy is one of the standard treatments for stage Ia2 to IIa cervical cancer. Bladder dysfunction caused by disruption of the pelvic autonomic nerves is a common complication following standard radical hysterectomy and can affect quality of life significantly. Nerve-sparing radical hysterectomy is a modified radical hysterectomy, developed to permit resection of oncologically relevant tissues surrounding the cervical lesion, while preserving the pelvic autonomic nerves. Read More

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http://dx.doi.org/10.1002/14651858.CD012828.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370917PMC
February 2019
1 Read

N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication.

Cochrane Database Syst Rev 2019 Feb 12;2:CD012357. Epub 2019 Feb 12.

Department of Evidence-Based Medicine, Intensive Care, Gastroenterology, Petrópolis Medical School, Av Barao do Rio Branco, 1003, Petrópolis, RJ, Brazil, 25680-120.

Background: Helicobacter pylori (H pylori) is one of the most common pathogens to establish and cause infection in human beings, affecting about 50% of the world's population. Prevalence may be as high as 83% in Latin American countries and as low as 17% in North America. Approximately 20% of infected people will manifest disease; people at high risk include those who live in low- and middle-income countries with poor sanitary conditions, since the mechanism of transmission seems to be oral-oral or faecal-oral (mostly during infancy). Read More

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http://dx.doi.org/10.1002/14651858.CD012357.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370586PMC
February 2019
5 Reads

Exercise-based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator.

Cochrane Database Syst Rev 2019 Feb 12;2:CD011828. Epub 2019 Feb 12.

Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark, 2100.

Background: An effective way of preventing sudden cardiac death is the use of an implantable cardioverter defibrillator (ICD). In spite of the potential mortality benefits of receiving an ICD device, psychological problems experienced by patients after receiving an ICD may negatively impact their health-related quality of life, and lead to increased readmission to hospital and healthcare needs, loss of productivity and employment earnings, and increased morbidity and mortality. Evidence from other heart conditions suggests that cardiac rehabilitation should consist of both exercise training and psychoeducational interventions; such rehabilitation may benefit patients with an ICD. Read More

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http://doi.wiley.com/10.1002/14651858.CD011828.pub2
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http://dx.doi.org/10.1002/14651858.CD011828.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371011PMC
February 2019
4 Reads

Combined hormonal contraceptives for heavy menstrual bleeding.

Cochrane Database Syst Rev 2019 Feb 11;2:CD000154. Epub 2019 Feb 11.

Department of Obstetrics and Gynaecology, University of Auckland, Private Bag 92019, Auckland, New Zealand, 1142.

Background: Menorrhagia or heavy menstrual bleeding (HMB) is an excessive blood loss that impairs a woman's quality of life, either physical, emotional, social or material. It is benign and not associated with pregnancy or any other gynaecological or systemic disease. Medical treatments used to reduce excessive menstrual blood loss (MBL) include prostaglandin synthetase inhibitors, antifibrinolytics, oral contraceptive pills, and other hormones. Read More

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http://dx.doi.org/10.1002/14651858.CD000154.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369862PMC
February 2019
3 Reads

Exercise training for advanced lung cancer.

Cochrane Database Syst Rev 2019 Feb 11;2:CD012685. Epub 2019 Feb 11.

Exercise Medicine Research Institute, Edith Cowan University, 270 Joondalup Drive, Joondalup, Australia, 6027.

Background: Patients with advanced lung cancer have a high symptom burden, which is often complicated by coexisting conditions. These issues, combined with the indirect effects of cancer treatment, can cumulatively lead patients to continued deconditioning and low exercise capacity. This is a concern as exercise capacity is considered a measure of whole body health, and is critical in a patient's ability to participate in life activities and tolerate difficult treatments. Read More

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http://dx.doi.org/10.1002/14651858.CD012685.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371641PMC
February 2019

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease.

Cochrane Database Syst Rev 2019 Feb 8;2:CD012839. Epub 2019 Feb 8.

Division of Digestive Diseases, University of California Los Angeles, 100 UCLA Medical Plaza, Suite 345, Los Angeles, California, USA, 90095.

Background: Inflammatory bowel disease (IBD), comprised of Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic mucosal inflammation, frequent hospitalizations, adverse health economics, and compromised quality of life. Diet has been hypothesised to influence IBD activity.

Objectives: To evaluate the efficacy and safety of dietary interventions on IBD outcomes. Read More

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http://dx.doi.org/10.1002/14651858.CD012839.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368443PMC
February 2019
1 Read

Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.

Cochrane Database Syst Rev 2019 Feb 8;2:CD003032. Epub 2019 Feb 8.

Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, P.le L.A. Scuro, 10, Verona, Verona, Italy, 37134.

Background: This is an updated version of the Cochrane Review previously published in 2017.Absence seizures (AS) are brief epileptic seizures which present in childhood and adolescence. Depending on clinical features and electroencephalogram (EEG) findings they are divided into typical, atypical absences, and absences with special features. Read More

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http://dx.doi.org/10.1002/14651858.CD003032.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367681PMC
February 2019

Antibiotics for induction and maintenance of remission in Crohn's disease.

Cochrane Database Syst Rev 2019 Feb 7;2:CD012730. Epub 2019 Feb 7.

Department of Medicine, University of Western Ontario, London, ON, Canada.

Background: Several antibiotics have been evaluated in Crohn's disease (CD), however randomised controlled trials (RCTs) have produced conflicting results.

Objectives: To assess the efficacy and safety of antibiotics for induction and maintenance of remission in CD.

Search Methods: We searched MEDLINE, Embase, CENTRAL, the Cochrane IBD Group Specialized Register and Clinicaltrials. Read More

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http://dx.doi.org/10.1002/14651858.CD012730.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366891PMC
February 2019
4 Reads

WITHDRAWN: Ozone therapy for the treatment of dental caries.

Cochrane Database Syst Rev 2019 Feb 7;2:CD004153. Epub 2019 Feb 7.

The Old Courthouse Dental Practice, 277 High Street, Dorking, Surrey, UK, RH4 1RY.

Background: Dental caries is a bacterially mediated disease characterised by demineralisation of the tooth surface, which may lead to cavitation, discomfort, pain and eventual tooth loss. Ozone is toxic to certain bacteria in vitro and it has been suggested that delivering ozone into a carious lesion might reduce the number of cariogenic bacteria. This possibly could arrest the progress of the lesion and may, in the presence of fluoride, perhaps allow remineralisation to occur. Read More

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http://dx.doi.org/10.1002/14651858.CD004153.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366652PMC
February 2019

WITHDRAWN: Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth.

Cochrane Database Syst Rev 2019 Feb 7;2:CD006384. Epub 2019 Feb 7.

Department of Dental Materials and Prosthesis, School of Dentistry of Ribeirão Preto, University of São Paulo, Av do Café s/nº, Ribeirão Preto, São Paulo, Brazil, 14040-904.

Background: Endodontic treatment of root canals or root canal treatment is a frequently performed dental procedure and is carried out on teeth in which irreversible pulpitis has led to necrosis (death) of the dental pulp (nerve). Removal of the necrotic tissue remnants and cleaning and shaping of the root canal are important phases of root canal treatment. Treatment options include the use of hand and rotary instruments and methods using ultrasonic or sonic equipment. Read More

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http://dx.doi.org/10.1002/14651858.CD006384.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366532PMC
February 2019

Ureteral stent versus no ureteral stent for ureteroscopy in the management of renal and ureteral calculi.

Cochrane Database Syst Rev 2019 Feb 6;2:CD012703. Epub 2019 Feb 6.

Department of Urology, University of Minnesota, 420 Delaware Street SE, MMC 394, Minneapolis, Minnesota, USA.

Background: Ureteroscopy combined with laser stone fragmentation and basketing is a common approach for managing renal and ureteral stones. This procedure is associated with some degree of ureteral trauma. Ureteral trauma may lead to swelling, ureteral obstruction, and flank pain and may require subsequent interventions such as hospital admission or secondary ureteral stent placement. Read More

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http://doi.wiley.com/10.1002/14651858.CD012703.pub2
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http://dx.doi.org/10.1002/14651858.CD012703.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365118PMC
February 2019
6 Reads

Thoracic endovascular repair (TEVAR) versus open surgery for blunt traumatic thoracic aortic injury.

Cochrane Database Syst Rev 2019 Feb 6;2:CD006642. Epub 2019 Feb 6.

NHS Grampian, Foresterhill Road, Aberdeen, UK, AB25 2ZN.

Background: Blunt traumatic thoracic aortic injury (BTAI) is a life-threatening surgical emergency associated with mortality up to 8000 per year, most commonly caused by rapid acceleration/deceleration injury sustained through motor vehicle accident and/or blunt thoracic trauma. BTAI has high pre-hospital mortality following the primary injury, with only 10% to 15% of patients surviving long enough to reach the hospital. Open surgical repair had remained the standard treatment option for BTAI since successfully introduced in 1959. Read More

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http://dx.doi.org/10.1002/14651858.CD006642.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363984PMC
February 2019
1 Read

Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted.

Cochrane Database Syst Rev 2019 Feb 5;2:CD006542. Epub 2019 Feb 5.

Department of Paediatric Dentistry, Leeds Dental Institute, Clarendon Way, Leeds, UK, LS2 9LU.

Background: Traumatic dental injuries are common. One of the most severe injuries is when a permanent tooth is knocked completely out of the mouth (avulsed). In most circumstances the tooth should be replanted as quickly as possible. Read More

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http://doi.wiley.com/10.1002/14651858.CD006542.pub3
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http://dx.doi.org/10.1002/14651858.CD006542.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363052PMC
February 2019
6 Reads

Subacromial decompression surgery for rotator cuff disease.

Cochrane Database Syst Rev 2019 01 17;1:CD005619. Epub 2019 Jan 17.

Monash Department of Clinical Epidemiology, Cabrini Institute and Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia, 3144.

Background: Surgery for rotator cuff disease is usually used after non-operative interventions have failed, although our Cochrane Review, first published in 2007, found that there was uncertain clinical benefit following subacromial decompression surgery.

Objectives: To synthesise the available evidence of the benefits and harms of subacromial decompression surgery compared with placebo, no intervention or non-surgical interventions in people with rotator cuff disease (excluding full thickness rotator cuff tears).

Search Methods: We searched CENTRAL, MEDLINE, Embase, Clinicaltrials. Read More

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http://doi.wiley.com/10.1002/14651858.CD005619.pub3
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http://dx.doi.org/10.1002/14651858.CD005619.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357907PMC
January 2019
13 Reads

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn.

Cochrane Database Syst Rev 2019 Feb 1;2:CD011724. Epub 2019 Feb 1.

Department of Paediatrics, Lund University, Skåne University Hospital, Lund, Sweden.

Background: Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It can be treated with either aspiration with a syringe (using a needle or an angiocatheter) or a chest tube inserted in the anterior pleural space and then connected to a Heimlich valve or an underwater seal with continuous suction.

Objectives: To compare the efficacy and safety of needle aspiration (either with immediate removal of the needle or with the needle left in situ) to intercostal tube drainage in the management of neonatal pneumothorax (PTX). Read More

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http://doi.wiley.com/10.1002/14651858.CD011724.pub3
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http://dx.doi.org/10.1002/14651858.CD011724.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357997PMC
February 2019
9 Reads

Interventions to promote patient utilisation of cardiac rehabilitation.

Cochrane Database Syst Rev 2019 Feb 1;2:CD007131. Epub 2019 Feb 1.

School of Kinesiology and Health Science, York University, 4700 Keele Street, Toronto, Ontario, Canada, M4P 2L8.

Background: International clinical practice guidelines routinely recommend that cardiac patients participate in rehabilitation programmes for comprehensive secondary prevention. However, data show that only a small proportion of these patients utilise rehabilitation.

Objectives: First, to assess interventions provided to increase patient enrolment in, adherence to, and completion of cardiac rehabilitation. Read More

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http://doi.wiley.com/10.1002/14651858.CD007131.pub4
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http://dx.doi.org/10.1002/14651858.CD007131.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360920PMC
February 2019
2 Reads

Interventions for treating urinary incontinence after stroke in adults.

Cochrane Database Syst Rev 2019 Feb 1;2:CD004462. Epub 2019 Feb 1.

Faculty of Health and Wellbeing, University of Central Lancashire, Room 416, Brook Building, Preston, Lancashire, UK, PR1 2HE.

Background: Urinary incontinence can affect 40% to 60% of people admitted to hospital after a stroke, with 25% still having problems when discharged from hospital and 15% remaining incontinent after one year.This is an update of a review published in 2005 and updated in 2008.

Objectives: To assess the effects of interventions for treating urinary incontinence after stroke in adults at least one-month post-stroke. Read More

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http://doi.wiley.com/10.1002/14651858.CD004462.pub4
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http://dx.doi.org/10.1002/14651858.CD004462.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355973PMC
February 2019
7 Reads

Interventions for intra-operative pain relief during postpartum mini-laparotomy tubal ligation.

Cochrane Database Syst Rev 2019 Feb 1;2:CD011807. Epub 2019 Feb 1.

Department of Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: Postpartum mini-laparotomy tubal ligation (PPTL) is a contraceptive method that works by interrupting the patency of the fallopian tubes. Several methods are used for intraoperative pain relief, such as systemic administration of opioids or intraperitoneal instillation of lidocaine.

Objectives: To evaluate the effectiveness of and adverse effects associated with interventions for pain relief in women undergoing PPTL. Read More

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http://doi.wiley.com/10.1002/14651858.CD011807.pub2
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http://dx.doi.org/10.1002/14651858.CD011807.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356148PMC
February 2019
6 Reads

Exercise for preventing falls in older people living in the community.

Cochrane Database Syst Rev 2019 Jan 31;1:CD012424. Epub 2019 Jan 31.

Institute for Musculoskeletal Health, School of Public Health, Faculty of Medicine and Health, The University of Sydney, PO Box 179, Missenden Road, Sydney, NSW, Australia, 2050.

Background: At least one-third of community-dwelling people over 65 years of age fall each year. Exercises that target balance, gait and muscle strength have been found to prevent falls in these people. An up-to-date synthesis of the evidence is important given the major long-term consequences associated with falls and fall-related injuries OBJECTIVES: To assess the effects (benefits and harms) of exercise interventions for preventing falls in older people living in the community. Read More

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http://dx.doi.org/10.1002/14651858.CD012424.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360922PMC
January 2019
2 Reads

Risk assessment tools for the prevention of pressure ulcers.

Cochrane Database Syst Rev 2019 01 31;1:CD006471. Epub 2019 Jan 31.

School of Nursing & Midwifery, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, Ireland, D2.

Background: Use of pressure ulcer risk assessment tools or scales is a component of the assessment process used to identify individuals at risk of developing a pressure ulcer. Use of a risk assessment tool is recommended by many international pressure ulcer prevention guidelines, however it is not known whether using a risk assessment tool makes a difference to patient outcomes. We conducted a review to provide a summary of the evidence pertaining to pressure ulcer risk assessment in clinical practice, and this is the third update of this review. Read More

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http://dx.doi.org/10.1002/14651858.CD006471.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354222PMC
January 2019
1 Read

Aerobic physical exercise for adult patients with haematological malignancies.

Cochrane Database Syst Rev 2019 01 31;1:CD009075. Epub 2019 Jan 31.

Cochrane Haematological Malignancies Group, Department I of Internal Medicine, University Hospital of Cologne, Kerpener Str. 62, Cologne, Germany.

Background: Although people with haematological malignancies have to endure long phases of therapy and immobility, which is known to diminish their physical performance level, the advice to rest and avoid intensive exercises is still common practice. This recommendation is partly due to the severe anaemia and thrombocytopenia from which many patients suffer. The inability to perform activities of daily living restricts them, diminishes their quality of life and can influence medical therapy. Read More

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http://dx.doi.org/10.1002/14651858.CD009075.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354325PMC
January 2019
1 Read

Phosphodiesterase 5 inhibitors for pulmonary hypertension.

Cochrane Database Syst Rev 2019 Jan 31;1:CD012621. Epub 2019 Jan 31.

Department of Respiratory Medicine, The Alfred Hospital, Commercial Rd, Melbourne, Australia, 3004.

Background: Pulmonary hypertension (PH) comprises a group of complex and heterogenous conditions, characterised by elevated pulmonary artery pressure, and which left untreated leads to right-heart failure and death. PH includes World Health Organisation (WHO) Group 1 pulmonary arterial hypertension (PAH); Group 2 consists of PH due to left-heart disease (PH-LHD); Group 3 comprises PH as a result of lung diseases or hypoxia, or both; Group 4 includes PH due to chronic thromboembolic occlusion of pulmonary vasculature (CTEPH), and Group 5 consists of cases of PH due to unclear and/or multifactorial mechanisms including haematological, systemic, or metabolic disorders. Phosphodiesterase type 5 (PDE5) inhibitors increase vasodilation and inhibit proliferation. Read More

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http://dx.doi.org/10.1002/14651858.CD012621.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354064PMC
January 2019
1 Read

Continuous positive airway pressure (CPAP) for acute bronchiolitis in children.

Cochrane Database Syst Rev 2019 01 31;1:CD010473. Epub 2019 Jan 31.

Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi, Delhi, India, 110029.

Background: Acute bronchiolitis is one of the most frequent causes of emergency department visits and hospitalisation in children. There is no specific treatment for bronchiolitis except for supportive treatment, which includes ensuring adequate hydration and oxygen supplementation. Continuous positive airway pressure (CPAP) aims to widen the lungs' peripheral airways, enabling deflation of overdistended lungs in bronchiolitis. Read More

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http://dx.doi.org/10.1002/14651858.CD010473.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354031PMC
January 2019
1 Read

General health checks in adults for reducing morbidity and mortality from disease.

Cochrane Database Syst Rev 2019 01 31;1:CD009009. Epub 2019 Jan 31.

Nordic Cochrane Centre, Rigshospitalet, Blegdamsvej 9, 7811, Copenhagen, Denmark, 2100.

Background: General health checks are common elements of health care in some countries. They aim to detect disease and risk factors for disease with the purpose of reducing morbidity and mortality. Most of the commonly used individual screening tests offered in general health checks have been incompletely studied. Read More

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http://dx.doi.org/10.1002/14651858.CD009009.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353639PMC
January 2019
1 Read

Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women.

Cochrane Database Syst Rev 2019 01 31;1:CD009218. Epub 2019 Jan 31.

Instituto Nacional de Salud Pública, Av. Universidad No. 655, Cuernavaca, Morelos, Mexico.

Background: Anaemia is a condition in which the number of red blood cells is insufficient to meet physiologic needs; it is caused by many conditions, particularly iron deficiency. Traditionally, daily iron supplementation has been a standard practice for preventing and treating anaemia. However, its long-term use has been limited, as it has been associated with adverse side effects such as nausea, constipation, and teeth staining. Read More

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http://dx.doi.org/10.1002/14651858.CD009218.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360921PMC
January 2019
2 Reads

Interventions to reduce shoulder pain following gynaecological laparoscopic procedures.

Cochrane Database Syst Rev 2019 Jan 30;1:CD011101. Epub 2019 Jan 30.

Women's Centre, Gloucestershire Hospitals NHS Foundation Trust, Gloucester Royal Hospital, Gloucester, UK, GL1 3NN.

Background: Laparoscopy is a common procedure used to diagnose and treat various gynaecological conditions. Shoulder-tip pain (STP) as a result of the laparoscopy occurs in up to 80% of women, with potential for significant morbidity, delayed discharge and readmission. Interventions at the time of gynaecological laparoscopy have been developed in an attempt to reduce the incidence and severity of STP. Read More

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http://dx.doi.org/10.1002/14651858.CD011101.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353625PMC
January 2019

Mesenchymal stromal cells as treatment or prophylaxis for acute or chronic graft-versus-host disease in haematopoietic stem cell transplant (HSCT) recipients with a haematological condition.

Cochrane Database Syst Rev 2019 Jan 30;1:CD009768. Epub 2019 Jan 30.

Systematic Review Initiative, NHS Blood and Transplant, Level 2, John Radcliffe Hospital, Headington, Oxford, Oxon, UK, OX3 9BQ.

Background: Recipients of allogeneic haematopoietic stem cell transplants (HSCT) can develop acute or chronic, or both forms of graft-versus-host disease (a/cGvHD), whereby immune cells of the donor attack host tissues. Steroids are the primary treatment, but patients with severe, refractory disease have limited options and a poor prognosis. Mesenchymal stromal cells (MSCs) exhibit immunosuppressive properties and are being tested in clinical trials for their safety and efficacy in treating many immune-mediated disorders. Read More

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http://dx.doi.org/10.1002/14651858.CD009768.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353308PMC
January 2019

Exercise-based cardiac rehabilitation for adults with heart failure.

Cochrane Database Syst Rev 2019 01 29;1:CD003331. Epub 2019 Jan 29.

Institute of Health Research, University of Exeter Medical School, Exeter, UK.

Background: Chronic heart failure (HF) is a growing global health challenge. People with HF experience substantial burden that includes low exercise tolerance, poor health-related quality of life (HRQoL), increased risk of mortality and hospital admission, and high healthcare costs. The previous (2014) Cochrane systematic review reported that exercise-based cardiac rehabilitation (CR) compared to no exercise control shows improvement in HRQoL and hospital admission among people with HF, as well as possible reduction in mortality over the longer term, and that these reductions appear to be consistent across patient and programme characteristics. Read More

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http://dx.doi.org/10.1002/14651858.CD003331.pub5DOI Listing
January 2019

School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review.

Cochrane Database Syst Rev 2019 01 28;1:CD011651. Epub 2019 Jan 28.

Centre for Child Health, Blizard Institute, Queen Mary University of London, London, UK, E1 2AT.

Background: Asthma is a common respiratory condition in children that is characterised by symptoms including wheeze, shortness of breath, chest tightness, and cough. Children with asthma may be able to manage their condition more effectively by improving inhaler technique, and by recognising and responding to symptoms. Schools offer a potentially supportive environment for delivering interventions aimed at improving self-management skills among children. Read More

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http://dx.doi.org/10.1002/14651858.CD011651.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353176PMC
January 2019

Topiramate for juvenile myoclonic epilepsy.

Cochrane Database Syst Rev 2019 01 28;1:CD010008. Epub 2019 Jan 28.

Department of Neurology, Xuanwu Hospital, Capital Medical University, Changchun Street 45, Beijing, China, 100053.

Background: Topiramate is a newer broad-spectrum antiepileptic drug (AED). Some studies have shown the benefits of topiramate in the treatment of juvenile myoclonic epilepsy (JME). However, there are no current systematic reviews to determine the efficacy and tolerability of topiramate in people with JME. Read More

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http://doi.wiley.com/10.1002/14651858.CD010008.pub4
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http://dx.doi.org/10.1002/14651858.CD010008.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353083PMC
January 2019
4 Reads

Pharmacotherapies for cannabis dependence.

Cochrane Database Syst Rev 2019 01 28;1:CD008940. Epub 2019 Jan 28.

Monash Addiction Research Centre, Monash University, Peninsula Campus, McMahons Road, Frankston, VIC, Australia, 3199.

Background: Globally, cannabis use is prevalent and widespread. There are currently no pharmacotherapies approved for treatment of cannabis use disorders.This is an update of a Cochrane Review first published in the Cochrane Library in Issue 12, 2014. Read More

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http://doi.wiley.com/10.1002/14651858.CD008940.pub3
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http://dx.doi.org/10.1002/14651858.CD008940.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360924PMC
January 2019
6 Reads

Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for the treatment of in-stent restenosis of the femoropopliteal arteries.

Cochrane Database Syst Rev 2019 01 26;1:CD012510. Epub 2019 Jan 26.

Division of Vascular Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Room H287, 2075 Bayview Avenue, Toronto, ON, Canada, M4N 3M5.

Background: Stents are placed in the femoropopliteal arteries for numerous reasons, such as atherosclerotic disease, the need for dissection, and perforation of the arteries, and can become stenosed with the passage of time. When a stent develops a flow-limiting stenosis, this process is known as "in-stent stenosis." It is thought that in-stent restenosis is caused by a process known as "intimal hyperplasia" rather than by the progression of atherosclerotic disease. Read More

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http://dx.doi.org/10.1002/14651858.CD012510.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353053PMC
January 2019
1 Read

Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women.

Cochrane Database Syst Rev 2019 Jan 25;1:CD010871. Epub 2019 Jan 25.

Clinical Research Institute, Faculty of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.

Background: The genital infection caused by Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) globally. The infection is mainly asymptomatic in women, thus it can produce infertility and chronic pelvic pain. In men infection is mainly symptomatic, but can evolve to prostatitis. Read More

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http://dx.doi.org/10.1002/14651858.CD010871.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353232PMC
January 2019
3 Reads

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults.

Cochrane Database Syst Rev 2019 01 24;1:CD012041. Epub 2019 Jan 24.

General Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, Hampshire, UK, SO16 6YD.

Background: Acute respiratory distress syndrome (ARDS) is an overwhelming systemic inflammatory process associated with significant morbidity and mortality. Pharmacotherapies that moderate inflammation in ARDS are lacking. Several trials have evaluated the effects of pharmaconutrients, given as part of a feeding formula or as a nutritional supplement, on clinical outcomes in critical illness and ARDS. Read More

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http://dx.doi.org/10.1002/14651858.CD012041.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353063PMC
January 2019
6 Reads