127 results match your criteria Coccidioidomycosis Thoracic


Thoracic Endemic Fungi in the United States: Importance of Patient Location.

Radiographics 2021 Mar-Apr;41(2):380-398. Epub 2021 Feb 5.

From the Department of Clinical Radiology, University of Missouri-Columbia, 1 Hospital Dr, Columbia, MO 65212 (J.R.K., A.H.); Department of Radiology, University of Southern California, Los Angeles, Calif (L.F.B.); Departments of Diagnostic Radiology (C.F.) and Pathology (D.S.), Oregon Health Sciences & University, Portland, Ore; and Department of Diagnostic Radiology, University of Kansas Medical Center, Kansas City, Kan (C.M.W.).

The digitization of radiographic studies along with high-speed transmission of images has formed the basis of teleradiology, which has become an integral component in the workflow of a contemporary radiology practice. It is with this advent and growing utilization of teleradiology that the significance of the source location of images has gained importance. Specifically, the importance of where the patient resides and what endemic fungi occur in that location cannot be underestimated. Read More

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February 2021

An Acute Pulmonary Coccidioidomycosis Coinfection in a Patient Presenting With Multifocal Pneumonia With COVID-19.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620972244

Private Practice, Bakersfield, CA, USA.

The ongoing coronavirus disease-2019 (COVID-19) pandemic has been the focus of health care workers as it has affected millions of people and cost hundreds of thousands of lives around the world. As hospitals struggle to identify and care for those afflicted with COVID-19, it is easy to overlook endemic diseases that potentially worsen or mimic the pulmonary manifestations or may coinfect those with COVID-19. In this case report, we present the case of a 48-year-old Hispanic female who was admitted with respiratory distress from an acute COVID-19 infection but was also found to have acute pulmonary coccidioidomycosis infection and was treated successfully. Read More

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November 2020

Clinical implications of pulmonary nodules detected in children.

Pediatr Pulmonol 2021 01 19;56(1):203-210. Epub 2020 Nov 19.

Division of Pediatric Respiratory Medicine, Department of Pediatrics, Rady Children's Hospital San Diego, University of California San Diego, San Diego, California, USA.

Introduction: The management of children found to have pulmonary nodules is not well established. We determined how often diagnostic testing was pursued, the outcome of diagnostic testing, and how often pulmonary nodules were given a definitive diagnosis.

Method: A retrospective review of patients found to have pulmonary nodules. Read More

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January 2021

Spinal Coccidioidomycosis: A Complication From Medication Noncompliance.

Cureus 2020 Jul 20;12(7):e9304. Epub 2020 Jul 20.

Pathology, Texas Tech University Health Sciences Center, Lubbock, USA.

Spinal coccidioidomycosis is a rare disseminated form of coccidioidomycosis infection. According to the literature, majority of patients are African American males. We present a rare case of spinal coccidioidomycosis in a young, Caucasian female with coccidioidomycosis meningitis at age 16 years who presented with bilateral lower extremity weakness after antifungal medication lapse for one year. Read More

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Endemic Fungi Presenting as Community-Acquired Pneumonia: A Review.

Semin Respir Crit Care Med 2020 Aug 6;41(4):522-537. Epub 2020 Jul 6.

Indiana University, School of Medicine, Pulmonary Critical Care Medicine, Thoracic Transplantation Program, Indianapolis, Indiana.

In endemic areas, dimorphic fungal infections due to , and account for up to 30% of cases of community-acquired pneumonia. Because respiratory manifestations are often indistinguishable from common bacterial causes of pneumonia, the diagnosis of pulmonary histoplasmosis, blastomycosis, and coccidioidomycosis is often delayed and associated with antibiotics overuse. In addition to being highly endemic to certain regions of North America, dimorphic fungi have global significance due to established areas of endemicity in all six inhabited continents, an increasingly interconnected world of travelers and transported goods, and a changing epidemiology as a result of global heating and anthropomorphic land utilization. Read More

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Bicavitary eosinophilic effusion in a dog with coccidioidomycosis.

J Vet Intern Med 2020 Jul 24;34(4):1582-1586. Epub 2020 May 24.

Department of Pathology and Population Medicine, College of Veterinary Medicine, Midwestern University, Glendale, Arizona, USA.

This is a case of coccidioidomycosis in a dog, examined for vomiting and labored breathing. Physical examination and thoracic and abdominal imaging revealed pleural and peritoneal effusions, both of which exhibited neutrophilic inflammation with a substantial eosinophilic component. The dog had positive IgM and IgG coccidioidomycosis titers at initial evaluation. Read More

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Case 2-2020: A 64-Year-Old Man with Fever and Respiratory Failure.

N Engl J Med 2020 Jan;382(3):276-285

From the Department of Internal Medicine, Yale School of Medicine, New Haven, CT (M.M.A.); and the Departments of Radiology (V.V.M.), Pathology (J.A.V., S.E.T.), and Medicine (S.E.T.), Massachusetts General Hospital, and the Departments of Radiology (V.V.M.), Pathology (J.A.V., S.E.T.), and Medicine (S.E.T.), Harvard Medical School - both in Boston.

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January 2020

Pulmonary Coccidioidomycosis Diagnosed by Endobronchial Ultrasound With Fine Needle Aspiration Biopsy of a Paratracheal Pulmonary Nodule.

J Bronchology Interv Pulmonol 2019 10;26(4):e63-e65

Interventional Pulmonary and Advanced Diagnostics, Dignity Health Norton Thoracic Institute, Phoenix, AZ.

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October 2019

A 37-Year-Old Man With Pleuritic Chest Pain.

Chest 2019 07;156(1):e15-e21

Pulmonary, Critical Care, and Sleep Medicine Section, Veterans Affairs Medical Center, La Jolla, CA; Division of Pulmonary, Critical Care, and Sleep Medicine, University of California San Diego School of Medicine, San Diego, CA.

Case Presentation: A 37-year-old man with poorly controlled type 2 diabetes presented with severe right-sided pleuritic chest pain, respiratory splinting, and cough. Two weeks earlier, he had been evaluated at an urgent care for cough and was prescribed a 5-day course of azithromycin for bronchitis. He then presented to our ED reporting mild, right-sided pleuritic chest pain. Read More

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Diagnosis of Fungal Infections. A Systematic Review and Meta-Analysis Supporting American Thoracic Society Practice Guideline.

Ann Am Thorac Soc 2019 09;16(9):1179-1188

Evidence-Based Practice Center, Mayo Clinic, Rochester, Minnesota.

Prompt diagnosis of invasive fungal infections is important because of the associated morbidity and mortality; however, diagnosis is challenging because of the nonspecific symptoms and radiographic findings. To conduct a systematic review and meta-analysis of studies that evaluated the diagnostic accuracy of serum and bronchoalveolar lavage (BAL) galactomannan (GM) and serum or BAL polymerase chain reaction (PCR) in patients with suspected invasive aspergillosis (IA), β-d-glucan in critically ill patients at risk for candidiasis or candidemia, and serology testing and antigen detection in patients with endemic mycoses (histoplasmosis, blastomycosis, and coccidioidomycosis). Studies were selected and appraised by pairs of reviewers. Read More

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September 2019

Endemic pulmonary fungal diseases in immunocompetent patients: an emphasis on thoracic imaging.

Expert Rev Respir Med 2019 03 31;13(3):263-277. Epub 2019 Jan 31.

a Department of Radiology , Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.

Introduction: Systemic endemic mycoses are prevalent in specific geographical areas of the world and are responsible for high rates of morbidity and mortality in these populations, and in immigrants and travelers returning from endemic regions. The most common fungal infections that can affect the lungs of immunocompetent patients include histoplasmosis, coccidioidomycosis, paracoccidioidomycosis, blastomycosis, sporotrichosis, aspergillosis, and cryptococcosis. Diagnosis and management of these diseases remain challenging, especially in non-endemic areas due to the lack of experience. Read More

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West African Man with a Cavitary Pneumonia and Cutaneous Nodule.

Am J Trop Med Hyg 2019 01;100(1):5-6

Division of Infectious Diseases, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona.

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January 2019

Tomographic assessment of thoracic fungal diseases: a pattern and signs approach.

Radiol Bras 2018 Sep-Oct;51(5):313-321

Department of Radiology, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.

Pulmonary fungal infections, which can be opportunistic or endemic, lead to considerable morbidity and mortality. Such infections have multiple clinical presentations and imaging patterns, overlapping with those of various other diseases, complicating the diagnostic approach. Given the immensity of Brazil, knowledge of the epidemiological context of pulmonary fungal infections in the various regions of the country is paramount when considering their differential diagnoses. Read More

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October 2018

Coccidioidomycosis in Nonhuman Primates: Pathologic and Clinical Findings.

Vet Pathol 2018 11 2;55(6):905-915. Epub 2018 Aug 2.

2 Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.

Coccidioidomycosis in nonhuman primates has been sporadically reported in the literature. This study describes 22 cases of coccidioidomycosis in nonhuman primates within an endemic region, and 79 cases of coccidioidomycosis from the veterinary literature are also reviewed. The 22 cases included baboons ( n = 10), macaques ( n = 9), and chimpanzees ( n = 3). Read More

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November 2018

Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease.

Respiration 2018;96(3):283-301. Epub 2018 Jun 28.

Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.

Systemic endemic mycoses cause high rates of morbidity and mortality in certain regions of the world and the real impact on global health is not well understood. Diagnosis and management remain challenging, especially in low-prevalence settings, where disease awareness is lacking. The main challenges include the variability of clinical presentation, the fastidious and slow-growing nature of the fungal pathogens, the paucity of diagnostic tests, and the lack of options and toxicity of antifungal drugs. Read More

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October 2019

Fever after recent travel.

Authors:
Habib Rehman

Cleve Clin J Med 2017 Nov;84(11):840-846

Clinical Associate Professor, Department of Medicine, Regina Qu'Appelle Health Region, Regina, SK, Canada.

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November 2017

The Imitation Game: A 55-Year-Old Man With a Lung and Adrenal Mass.

J Bronchology Interv Pulmonol 2017 10;24(4):e52-e54

*Department of Pulmonary, Critical Care and Sleep Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA †Department of Hospital Medicine Medicine Institute, Cleveland Clinic, Cleveland, OH ‡Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

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October 2017

Spinal Coccidioidomycosis: A Current Review of Diagnosis and Management.

World Neurosurg 2017 Dec 24;108:69-75. Epub 2017 Aug 24.

Department of Neurosurgery, Barrow Neurological Institute, Saint Joseph's Hospital and Medical Center, Phoenix, Arizona, USA. Electronic address:

Objective: Coccidioidomycosis is an invasive fungal disease that may present with extrathoracic dissemination. Patients with spinal coccidioidomycosis require unique medical and surgical management. We review the risk factors and clinical presentations, discuss the indications for surgical intervention, and evaluate outcomes and complications after medical and surgical management. Read More

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December 2017

[A case of coccidioidomycosis in Turkey imported from the United States of America].

Mikrobiyol Bul 2017 Apr;51(2):183-190

Istanbul University Istanbul Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Turkey.

Coccidioidomycosis caused by Coccidioides immitis or Coccidioides posadasii is a rare infectious disease except in endemic regions. In this report the third documented imported case of coccidioidomycosis in Turkey was presented. A thirty-year-old male patient was admitted to our hospital with fever and purulent drainage from his chest tube. Read More

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Hydropneumothorax from a Ruptured Coccidioides Cavity.

Authors:
Charles W Lanks

Am J Respir Crit Care Med 2017 Jul;196(2):240

Department of Medicine, Harbor-University of California, Los Angeles Medical Center, Torrance, California.

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Executive Summary: 2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis.

Clin Infect Dis 2016 09;63(6):717-22

Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona.

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. Infectious Diseases Society of America considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances. Read More

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September 2016

2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis.

Clin Infect Dis 2016 09 27;63(6):e112-46. Epub 2016 Jul 27.

Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona.

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. Infectious Diseases Society of America considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances. Read More

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September 2016

Thoracic lymphadenopathy in benign diseases: A state of the art review.

Respir Med 2016 Mar 1;112:10-7. Epub 2016 Feb 1.

Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil. Electronic address:

Lymphadenopathy is a common radiological finding in many thoracic diseases and may be caused by a variety of infectious, inflammatory, and neoplastic conditions. This review aims to describe the patterns of mediastinal and hilar lymphadenopathy found in benign diseases in immunocompetent patients. Computed tomography is the method of choice for the evaluation of lymphadenopathy, as it is able to demonstrate increased size of individual nodes, abnormalities of the interface between the mediastinum and lung, invasion of surrounding fat, coalescence of adjacent nodes, obliteration of the mediastinal fat, and hypo- and hyperdensity in lymph nodes. Read More

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Peritoneal Coccidioidomycosis: a Rare Case Report and Review of the Literature.

J Gastrointestin Liver Dis 2015 Dec;24(4):527-30

Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305 USA.

Coccidioidomycosis is a fungal infection endemic to the southwestern United States that typically causes a self-limited pulmonary illness. Extrapulmonary dissemination is extremely rare and typically localized to the skin, bone, and meninges. The gastrointestinal system has generally been thought to be spared from this disease. Read More

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December 2015

Empyema necessitatis: unique presentation in a coccidioidomycosis case.

Am J Respir Crit Care Med 2015 Apr;191(8):964-6

1 Universidad Autónoma de Nuevo León Monterrey, México.

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Case 209: Disseminated coccidioidal spondylodiskitis.

Radiology 2014 Sep;272(3):914-8

From the Department of Radiology, Nassau University Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554.

History A 46-year-old Hispanic man with a medical history of diabetes and hepatitis C and an unclear history of prior infectious disease presented to the emergency department of a community medical center in the northeastern United States with a 3-month history of back pain. The patient was originally from Mexico and had been living in the United States for approximately 1 year. Physical examination at the time of admission was noncontributory. Read More

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September 2014

Pulmonary coccidioidomycosis: pictorial review of chest radiographic and CT findings.

Radiographics 2014 Jul-Aug;34(4):912-25

From the Department of Radiology, Olive View-UCLA Medical Center, 14445 Olive View Dr, 2D115, Sylmar, CA 91342 (C.M.J., M.K.P., M.D.); Imaging Services, West Los Angeles VA Medical Center, Los Angeles, Calif (C.M.J., P.B.); and Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, Calif (C.M.J., N.B.N., M.K.P., M.D., P.B.).

Pulmonary coccidioidomycosis is a fungal disease endemic to the desert regions of the southwestern United States, Mexico, Central America, and South America. The incidence of reported disease increased substantially between 1998 and 2011, and the infection is encountered beyond the endemic areas because of a mobile society. The disease is caused by inhalation of spores of Coccidioides species. Read More

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November 2015

Video-assisted thoracoscopic surgery for patients with pulmonary coccidioidomycosis.

J Thorac Cardiovasc Surg 2014 Oct 8;148(4):1217-23. Epub 2014 Feb 8.

Division of Cardiovascular and Thoracic Surgery, Mayo Clinic Hospital, Phoenix, Ariz. Electronic address:

Objective: The study objective was to evaluate the use of video-assisted thoracoscopic surgery for removal of pulmonary sequelae of the fungal infection coccidioidomycosis.

Methods: Retrospective chart review of all patients with pulmonary coccidioidomycosis treated surgically at our tertiary care center between January 1, 2009, and August 31, 2012.

Results: Of 2166 patients treated for pulmonary coccidioidomycosis, 58 (2. Read More

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October 2014

Rare manifestations of coccidioidomycosis.

J La State Med Soc 2013 May-Jun;165(3):137-9

Tulane University Medical Center, New Orleans, USA.

Involvement of the central nervous system and extrapulmonary sites by Coccidioides immitis is reported primarily in patients with cell-mediated immune deficiency. We present a case of a patient with no prior history of immunosuppression who presented to a public hospital in New Orleans with disseminated Coccidioides infection. Read More

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December 2013

Pediatric coccidioidomycosis in central California: a retrospective case series.

Clin Infect Dis 2013 Jun 5;56(11):1579-85. Epub 2013 Mar 5.

Department of Pediatrics, Children's Hospital Central California, Madera, CA 93638, USA.

Background: Coccidioidomycosis, an endemic fungal infection seen throughout the southwestern United States, is not well described in children.

Methods: We performed a retrospective observational study of all children admitted to Children's Hospital Central California with coccidioidomycosis from 1 January 2010 to 1 September 2011.

Results: Thirty-three children, aged 6 months to 17 years, were hospitalized during the study period. Read More

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