1,241 results match your criteria Coal Worker's Pneumoconiosis

Interstitial lung abnormalities and interstitial lung diseases associated with cigarette smoking in a rural cohort undergoing surgical resection.

BMC Pulm Med 2022 Apr 29;22(1):172. Epub 2022 Apr 29.

Deparment of Pathology, West Virginia University, Morgantown, WV, USA.

Background: Cigarette smoking is a risk factor for interstitial lung abnormalities (ILAs) and interstitial lung diseases (ILDs). Investigation defining the relationships between ILAs/ILDs and clinical, radiographic, and pathologic findings in smokers have been incomplete. Employing a cohort undergoing surgical resection for lung nodules/masses, we (1) define the prevalence of ILAs/ILDs, (2) delineate their clinical, radiographic and pathologic predictors, and (3) determine their associations with mortality. Read More

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[Analysis on epidemiological characteristics of pneumoconiosis in Qinghai Province from 2011 to 2020].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2022 Mar;40(3):200-203

Department of Public Health, Medical College, Qinghai University, Xining 810001, China Qinghai Center for Disease Control and Prevention, Xining 810007, China.

To analyze the epidemiological characteristics of pneumoconiosis in Qinghai Province from 2011 to 2020, and to provide a basis for the formulation of prevention and control strategy. In April 2021 , the cases of pneumoconiosis were monitored by the Occupational Disease and Health Hazard Factors Monitoring Information System in Qinghai Province from 2011 to 2020. The distribution of pneumoconiosis, the composition of diseases and the working years exposed to dust were analyzed. Read More

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The visceral pleura, lung cancer and lymphatic spread.

David G Healy

Eur J Cardiothorac Surg 2022 Apr 19. Epub 2022 Apr 19.

Department Thoracic Surgery, St Vincent's University Hospital, Dublin, Ireland.

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J Cell Physiol 2022 Apr 13. Epub 2022 Apr 13.

Retraction: "TNF-α-TNFR signal pathway inhibits autophagy and promotes apoptosis of alveolar macrophages in coal worker's pneumoconiosis," by Qingzeng Qian, Xiangke Cao, Bin Wang, Yi Qu, Qingqiang Qian, Zhiqian Sun, Fumin Feng, J Cell Physiol. 2019; 5953-5963: The above article, published online on 23 November 2018 in Wiley Online Library (https://doi.org/10. Read More

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Giant Cell Interstitial Pneumonia In Native, Transplanted And Re-Transplanted Lungs 8 Years Apart Without Known Hard Metal Exposure.

Int J Surg Pathol 2022 Apr 5:10668969221092113. Epub 2022 Apr 5.

Department of Pulmonary and Critical Care Medicine, Cleveland Clinic, Cleveland, Ohio, USA.

Pneumoconioses are a group of non-neoplastic pulmonary disorders caused by inhaled inorganic particles. Well-described pneumoconioses include asbestosis, silicosis, coal worker's pneumoconiosis, chronic beryllium disease, and hard metal lung disease. Giant cell interstitial pneumonia (GIP) is a distinctive and rare pneumoconiosis most frequently found in workers exposed to hard metals, primarily cobalt and tungsten carbide. Read More

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Effects of Light-absorbing Carbons in Intraoperative Molecular Imaging-Guided Lung Cancer Resections.

Mol Imaging Biol 2022 Mar 15. Epub 2022 Mar 15.

Department of Thoracic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Background: One of the novel advancements to enhance the visual aspects of lung cancer identification is intraoperative molecular imaging (IMI), which can reliably detect tumors that would otherwise be missed by standard techniques such as tactile and visual feedback, particularly for sub-centimeter or ground-glass nodules. However, there remains a subset of patients who do not benefit from IMI due to excessive background fluorescence secondary to parenchymal light-absorbing carbon deposition. Our goal was to identify the effects of these carbonaceous materials on the quality of IMI-guided lung cancer resections. Read More

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[Expression and functional SNP loci screen of from coal worker's pneumoconiosis].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2022 Feb;40(2):103-108

College of Public Health of Guizhou Medical University, Guiyang 550004, China Public Health Treatment Center of Guiyang, Guiyang 550004, China.

To detect of gene expression and genotype of the ataxia telangiectasia mutated () from coal workers' pneumoconiosis (CWP) , It is explored whether CWP is related to gene. In October 2020, the relevant information of 264 subjects who received physical examination or medical treatment in the Department of occupational diseases of Guiyang public health treatment center from January 2019 to September 2020 was collected. Through the occupational health examination, 67 healthy people with no history of exposure to occupational hazards were selected as the healthy control group; The coal miners with more than 10 years of coal dust exposure history and small shadow in the lung but not up to the diagnostic criteria were the dust exposure control group, a total of 66 people; The patients with the same history of coal dust exposure and confirmed stage I were coal worker's pneumoconiosis stage I group, a total of 131 people. Read More

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February 2022

Cost-effectiveness of comprehensive preventive measures for coal workers' pneumoconiosis in China.

BMC Health Serv Res 2022 Feb 28;22(1):266. Epub 2022 Feb 28.

Department of Health Statistics, School of Public Health, Jinzhou Medical University, No. 40 Songpo Road, Jinzhou, Liaoning, 121000, People's Republic of China.

Background: Coal workers' pneumoconiosis (CWP) remains one of the most severe occupational diseases in China. Despite the implementation of CWP comprehensive preventive measures, the unreasonable allocation of investment by coal enterprises limits the effect of preventing CWP, especially when the health resources are inadequate. This study aims to evaluate the cost-effectiveness of comprehensive measures for CWP from the perspective of coal enterprises. Read More

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February 2022

Altered lymphatic structure and function in pleural anthracosis: negative role in skip N2 metastasis.

Eur J Cardiothorac Surg 2022 Feb 25. Epub 2022 Feb 25.

Department of General Thoracic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Objectives: The present study investigated whether or not pleural anthracosis is associated with changes in the pleural lymphatic structures or function, which would interfere with nodal skip metastasis.

Methods: This study comprised 2 different case series. In the first series, we observed pleural lymphatic drainage using near-infrared fluorescent endoscopy by the subpleural injection of indocyanine green immediately after thoracotomy for lung cancer. Read More

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February 2022

Estimating mortality from coal workers' pneumoconiosis among Medicare beneficiaries with pneumoconiosis using binary regressions for spatially sparse data.

Am J Ind Med 2022 04 8;65(4):262-267. Epub 2022 Feb 8.

Department of Public Health Sciences, The University of North Carolina at Charlotte, Charlotte, North Carolina, USA.

Background: Coal workers' pneumoconiosis (CWP) is an occupational lung disease due to inhalation of coal dust. We estimated mortality from CWP and other pneumoconioses among Medicare beneficiaries.

Methods: We used the 5% Medicare Limited Claims Data Set, 2011-2014, to identify patients diagnosed with ICD-9-CM 500 (CWP) through 505 (Asbestosis, Pneumoconiosis due to other silica or silicates, Pneumoconiosis due to other inorganic dust, Pneumonopathy due to inhalation of other dust, and Pneumoconiosis, unspecified) codes. Read More

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Analysis of Histopathological Findings of Lung Carcinoma in Czech Black Coal Miners in Association with Coal Workers' Pneumoconiosis.

Int J Environ Res Public Health 2022 01 9;19(2). Epub 2022 Jan 9.

Department of Epidemiology and Public Health, Faculty of Medicine, University of Ostrava, Syllabova 19, 703 00 Ostrava, Czech Republic.

Coal miners with coal workers' pneumoconiosis (CWP, J60 according to ICD-10) were previously found to have a significantly higher risk of lung carcinoma compared to the general male population. The presented study aimed to analyze the (i) incidence of lung carcinoma in miners, (ii) histopathological findings in cohorts with and without CWP, and (iii) effect of smoking cessation on the histopathological profile. Analyzed cohorts consisted of miners with ( = 3476) and without ( = 6687) CWP. Read More

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January 2022

Respiratory health of American Indian and Alaska Native coal miners participating in the Coal Workers' Health Surveillance Program, 2014-2019.

Am J Ind Med 2022 03 14;65(3):162-165. Epub 2022 Jan 14.

Surveillance Branch, Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, USA.

Background: In 2014, a federal rule reduced occupational exposure limits to coal mine dust and expanded medical surveillance eligibility beyond underground miners to surface and contract coal miners. This expansion may have provided an opportunity for more American Indian and Alaska Native (AI/AN) coal miners to participate in screening, since many surface coal mines are located near AI/AN communities and may employ AI/AN miners. Therefore we sought to better understand the respiratory health of AI/AN coal miners by characterizing prevalence of coal workers' pneumoconiosis (CWP), progressive massive fibrosis (PMF), and abnormal lung function in this population. Read More

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Reply: Radiologic Classification of Black Lung: Time for a New Gold Standard?

Ann Am Thorac Soc 2022 Apr;19(4):702-703

University of Illinois Chicago Chicago, Illinois.

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J Zoo Wildl Med 2021 Dec;52(4):1123-1134

Royal Veterinary College, North Mymms, Hatfield, Hertfordshire, AL9 7TA, United Kingdom.

Langurs are Asian primates belonging to the Colobinae subfamily. Langur populations are declining, with most species categorized as threatened by the International Union for Conservation of Nature. Investigation into the threats to population viability and sustainability would be beneficial but there is limited literature available on common diseases or causes of death in these species, either in captive or free-ranging settings. Read More

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December 2021

Heterozygous Ins/Del genotype of the CASP8 rs3834129 polymorphism significantly decreases the risk of coal workers' pneumoconiosis in a Chinese Han population: a case-control study.

Eur Rev Med Pharmacol Sci 2021 Dec;25(24):7726-7733

Department of Pulmonary and Critical Care Medicine, Sinopharm Tongmei General Hospital, Shanxi, China.

Objective: Coal workers' pneumoconiosis (CWP) is a chronic inflammatory and fibrotic pulmonary disease that involves a complex interaction of multiple environmental and genetic factors. Polymorphism, as a genetic factor, may affect the onset of the disease in susceptible populations. The present study investigated the association between the polymorphisms of six genes and CWP risk in a Chinese Han population. Read More

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December 2021

Elucidating the Etiologies of 18F-fluorodeoxyglucose-Avid Mediastinal Lymph Nodes Among Cancer Patients in a Tuberculosis-Endemic Region Using Endobronchial Ultrasound.

Cureus 2021 Nov 7;13(11):e19339. Epub 2021 Nov 7.

Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

Background Non-malignant conditions, including infections (such as tuberculosis [TB]), can mimic malignancy with regards to their uptake of 18F-fluorodeoxyglucose (F-FDG) tracer utilized for positron emission tomography-computed tomography (PET-CT) scan, as part of the diagnostic and staging workup of cancer patients. This poses a diagnostic challenge, for which tissue sampling is decisive. In this study, we aimed to determine the underlying etiologies of F-FDG-avid mediastinal lymph nodes among cancer patients in a TB-endemic demographic using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and the respective sensitivity and specificity of PET-CT and EBUS in diagnosing malignancy. Read More

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November 2021

Coal mine dust lung disease in miners killed in the Upper Big Branch disaster: a review of lung pathology and contemporary respirable dust levels in underground US coal mines.

Occup Environ Med 2022 May 8;79(5):319-325. Epub 2021 Dec 8.

Environmental and Occupational Health Sciences Division, School of Public Health, University of Illinois Chicago, Chicago, Illinois, USA.

Objectives: In 2010, 29 coal miners died due to an explosion at the Upper Big Branch (UBB) mine in West Virginia, USA. Autopsy examinations of 24 individuals with evaluable lung tissue identified 17 considered to have coal workers' pneumoconiosis (CWP). The objectives of this study were to characterise histopathological findings of lung tissue from a sample of UBB fatalities and better understand the respirable dust concentrations experienced by these miners at UBB relative to other US coal mines. Read More

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Exploration study on serum metabolic profiles of Chinese male patients with artificial stone silicosis, silicosis, and coal worker's pneumoconiosis.

Toxicol Lett 2022 Mar 30;356:132-142. Epub 2021 Nov 30.

Department of Occupational Medical and Environmental Health, Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, PR China. Electronic address:

Long-term exposure to inhaled silica dust induces pneumoconiosis, which remains a heavy burden in developing countries. Modern industry provides new resources of occupational SiO leading to artificial stone silicosis especially in developed countries. This study aimed to characterize the serum metabolic profile of pneumoconiosis and artificial stone silicosis patients. Read More

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Assessment of intrathoracic lymph nodes by FDG PET/CT in patients with asbestos-related lung cancer.

J Thorac Dis 2021 Oct;13(10):5925-5932

Department of Surgery, Okayama Rosai Hospital, Chikkomidorimachi, Minamiku, Okayama, Japan.

Background: This study explored the assessment of intrathoracic lymph node metastasis by 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography computed tomography (PET/CT) in patients with asbestos-related lung cancer (ARLC).

Methods: We retrospectively reviewed the data on 35 patients with ARLC who underwent preoperative FDG-PET/CT and surgical resection between January 2012 and December 2018. We collected medical information from medical records and imaging systems and examined the FDG uptake in each lymph nodal region resected by surgery and the presence or absence of pathological lymph node metastasis. Read More

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October 2021

Anthracosis, a Distinct Cause of Vocal Fold Paralysis: Case Series.

J Voice 2021 Nov 6. Epub 2021 Nov 6.

Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Vocal fold paralysis (VFP) can happen in various conditions due to mediastinal LADs, however no study has proposed anthracosis as an etiology. Here we discussed the chest CT features of anthracosis related LADs causing VFP. Among 41 cases of pulmonary anthracosis, 10 had VFP that all were presented with hoarseness. Read More

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November 2021

Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology.

Cancer Res 2021 12 19;81(23):5862-5875. Epub 2021 Oct 19.

Research Unit Analytical Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

Asymptomatic anthracosis is the accumulation of black carbon particles in adult human lungs. It is a common occurrence, but the pathophysiologic significance of anthracosis is debatable. Using high mass resolution matrix-assisted laser desorption/ionization (MALDI) fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging analysis, we discovered noxious carbon-bound exogenous compounds, such as polycyclic aromatic hydrocarbons (PAH), tobacco-specific nitrosamines, or aromatic amines, in a series of 330 patients with lung cancer in highly variable and unique patterns. Read More

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December 2021

[Clinical characteristics of coal worker's peneumoconiosis complicated with acute exacerbation of chronic obstractive pulno-mary disease].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2021 Sep;39(9):661-664

The Third People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830011, China.

To investigate the clinical characteristics of acute exacerbation of acute lung disease (AECOPD) and to provide reference for clinical diagnosis and treatment. From January 2018 to December 2018, 127 patients with AECOPD were investigated retrospectively in March 2020, including 65 cases of pneumoconiosis with AECOPD group, 62 cases of AECOPD group, 127 cases of AECOPD group, the clinical characteristics, length of stay, cost difference and the correlation between pulmonary function and blood gas were analyzed in patients with AECOPD. There was no significant difference in age, height, weight, BMI, ethnicity and smoking between the two groups (>0. Read More

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September 2021

Incidence and disease burden of coal workers' pneumoconiosis worldwide, 1990-2019: evidence from the Global Burden of Disease Study 2019.

Eur Respir J 2021 11 25;58(5). Epub 2021 Nov 25.

Dept of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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November 2021

Bronchial Anthracofibrosis and Tracheobronchomalacia.

Arch Iran Med 2021 06 1;24(6):467-472. Epub 2021 Jun 1.

Afzalipour Hospital Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Background: Tracheobronchomalacia (TBM), presenting with the softening of the walls of trachea and bronchi, can cause respiration problems. Despite the importance of TBM, data on its prevalence and related factors are limited. In the current study, the prevalence and predictive factors of this illness were investigated. Read More

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[Analysis of chronic obstructive pulmonary disease screening questionnaire and pulmonary function test among migrant workers exposed to dust].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2021 Aug;39(8):582-585

Hunan Prevention and Treatment Center for Occupational Diaseases, Changsha 410007, China.

To analyze the application of Chronic Obstructive Pulmonary Disease (COPD) Screening Questionnaire and pulmonary function test in dust-exposed migrant workers. In May 2019, 149 cases of dust exposed migrant workers were selected as the research subjects through the free clinic in the countryside. COPD Screening Questionnaire and lung function test were carried out to analyze the high-risk groups and the influencing factors of positive pulmonary function test results. Read More

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Biochemical and cytological analyses of pleural effusion in patients with lung anthracosis and antracofibrosis.

Ann Med Surg (Lond) 2021 Sep 13;69:102686. Epub 2021 Aug 13.

- Pulmonary and Critical Care Division, Imam Khomeini Hospital, Iranian National Registry Center for Lophomoniasis (INRCL), Mazandaran University of Medical Sciences, Sari, Iran.

Background: Anthracosis and anthracofibrosis are attributed to the deposition of carbon particles along with fibrosis, adhesion, narrowing, and collapse. There has been no study on the characteristics of the pleural fluid in anthracosis. The present study analyzed the biochemical characteristics of pleural effusion in patients with pulmonary anthracosis. Read More

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September 2021

A retrospective observational study of benign anthracotic lymphadenitis and its association with PET avid lymph nodes in patients undergoing cancer evaluation.

J Thorac Dis 2021 Jul;13(7):4228-4235

Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA, USA.

Background: Accurate staging of newly diagnosed or recurrent malignancy is essential for effective treatment. An important first step in staging involves the use of PET/CT to identify areas of FDG avidity. PET/CT however has limitations, including false positive FDG uptake from benign causes. Read More

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A systematic review and meta-analysis on international studies of prevalence, mortality and survival due to coal mine dust lung disease.

PLoS One 2021 3;16(8):e0255617. Epub 2021 Aug 3.

Cancer Council Queensland, Brisbane, Queensland, Australia.

Background: Coal mine dust lung disease comprises a group of occupational lung diseases including coal workers pneumoconiosis. In many countries, there is a lack of robust prevalence estimates for these diseases. Our objective was to perform a systematic review and meta-analysis of published contemporary estimates on prevalence, mortality, and survival for coal mine dust lung disease worldwide. Read More

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November 2021

The mystery of black lungs in a patient with calciphylaxis.

J Nephrol 2021 10 20;34(5):1553-1555. Epub 2021 Jul 20.

Institute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nanjing, 210009, Jiangsu, China.

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October 2021