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    131 results match your criteria Cnidaria Envenomation

    1 OF 3

    Crude venom from nematocysts of Pelagia noctiluca (Cnidaria: Scyphozoa) elicits a sodium conductance in the plasma membrane of mammalian cells.
    Sci Rep 2017 Jan 23;7:41065. Epub 2017 Jan 23.
    Paracelsus Medical University, Institute of Pharmacology and Toxicology, Strubergasse 21, Salzburg, A-5020, Austria.
    Cnidarians may negatively impact human activities and public health but concomitantly their venom represents a rich source of bioactive substances. Pelagia noctiluca is the most venomous and abundant jellyfish of the Mediterranean Sea and possesses a venom with hemolytic and cytolytic activity for which the mechanism is largely unknown. Here we show that exposure of mammalian cells to crude venom from the nematocysts of P. Read More

    Characterising the enzymatic profile of crude tentacle extracts from the South Atlantic jellyfish Olindias sambaquiensis (Cnidaria: Hydrozoa).
    Toxicon 2016 Sep 8;119:1-7. Epub 2016 May 8.
    Laboratório de Imunopatologia, Instituto Butantan, Av. Vital Brasil 1500, 05503-900 São Paulo, SP, Brazil. Electronic address:
    Jellyfish venoms are of medical and biotechnological importance, with toxins displaying antimicrobial, analgesic and anti-tumor activities. Although proteolytic enzymes have also been described, detailed characterisation of these proteins is scant in Olindias spp. High throughput mass spectrometry profiling of cnidarian venoms has become increasingly popular since the first description of the proteomic profile of putative toxins isolated from nematocysts of the hydrozoan jellyfish Olindias sambaquiensis describing the presence of orthologous enzymes as presented in venoms of advanced species as snakes. Read More

    The magnitude of severe box jellyfish cases on Koh Samui and Koh Pha-ngan in the Gulf of Thailand.
    BMC Res Notes 2016 Feb 17;9:108. Epub 2016 Feb 17.
    Epidemiology Bureau, Department of Disease Control, Ministry of Public Health, Nonthaburi, 10100, Thailand.
    Background: Despite recent deaths caused by box jellyfish envenomation occurring on the islands of Samui and Pha-ngan in the Gulf of Thailand, many people do not believe box jellyfish can kill humans and many people dismiss the problem as insignificant. More evidence has been requested from the communities in order to evaluate the need for and the implementation of sustainable prevention measures. We aimed to determine the magnitude of cases of severe stinging by box jellyfish and describe the characteristics of these cases on the islands of Samui and Pha-ngan in Surat Thani Province from 1997 to 2015. Read More

    Experimental Assays to Assess the Efficacy of Vinegar and Other Topical First-Aid Approaches on Cubozoan (Alatina alata) Tentacle Firing and Venom Toxicity.
    Toxins (Basel) 2016 Jan 11;8(1). Epub 2016 Jan 11.
    Békésy Laboratory of Neurobiology, Pacific Biosciences Research Center, School of Ocean and Earth Science and Technology, University of Hawaii at Manoa, Honolulu HI 96822, USA.
    Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that (1) recapitulate live-tentacle stings; (2) allow quantitation and imaging of cnidae discharge; (3) allow primary quantitation of venom toxicity; and (4) employ rigorous controls. We report the implementation of an integrated array of three experimental approaches designed to meet the above-stated criteria. Read More

    Protective effects of batimastat against hemorrhagic injuries in delayed jellyfish envenomation syndrome models.
    Toxicon 2015 Dec 4;108:232-9. Epub 2015 Nov 4.
    Marine Bio-pharmaceutical Institute, Second Military Medical University, Shanghai 200433, China; Department of Marine Biotechnology, Faculty of Naval Medicine, Second Military Medical University, Shanghai 200433, China. Electronic address:
    Previously, we established delayed jellyfish envenomation syndrome (DJES) models and proposed that the hemorrhagic toxins in jellyfish tentacle extracts (TE) play a significant role in the liver and kidney injuries of the experimental model. Further, we also demonstrated that metalloproteinases are the central toxic components of the jellyfish Cyanea capillata (C. capillata), which may be responsible for the hemorrhagic effects. Read More

    Apoptosis-like cell death induced by nematocyst venom from Chrysaora helvola Brandt jellyfish and an in vitro evaluation of commonly used antidotes.
    Comp Biochem Physiol C Toxicol Pharmacol 2016 Feb 30;180:31-9. Epub 2015 Oct 30.
    Department of Cell Biology and Genetics, Guangxi Medicinal University, Nanning 530021, China. Electronic address:
    The present work investigated the in vitro cytotoxicity of nematocyst venom (NV) from Chrysaora helvola Brandt (C. helvola) jellyfish against human MCF-7 and CNE-2 tumor cell lines. Potent cytotoxicity was quantified using the MTT assay (LC50=12. Read More

    Severe Toxic Skin Reaction Caused by a Common Anemone and Identification of the Culprit Organism.
    J Travel Med 2015 Jul-Aug;22(4):269-71
    Koç University Hospital, Istanbul, Turkey.
    In a marine envenomation, identification of the culprit organism can be difficult. In this case report, we present our method to identify snakelocks anemone (Anemonia viridis or formerly Anemonia sulcata) as the culprit of a severe toxic skin reaction. A. Read More

    Ancient Venom Systems: A Review on Cnidaria Toxins.
    Toxins (Basel) 2015 Jun 18;7(6):2251-71. Epub 2015 Jun 18.
    Venom Evolution Lab, School of Biological Sciences, the University of Queensland, St. Lucia 4072, QLD, Australia.
    Cnidarians are the oldest extant lineage of venomous animals. Despite their simple anatomy, they are capable of subduing or repelling prey and predator species that are far more complex and recently evolved. Utilizing specialized penetrating nematocysts, cnidarians inject the nematocyst content or "venom" that initiates toxic and immunological reactions in the envenomated organism. Read More

    Transcriptome and venom proteome of the box jellyfish Chironex fleckeri.
    BMC Genomics 2015 May 27;16:407. Epub 2015 May 27.
    Infectious Diseases Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
    Background: The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe localized and systemic effects that are potentially life-threatening. In this study, a combined transcriptomic and proteomic approach was used to identify C. Read More

    Jellyfish Stings: A Practical Approach.
    Wilderness Environ Med 2015 Sep 29;26(3):422-9. Epub 2015 Apr 29.
    Department of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
    Jellyfish have a worldwide distribution. Their stings can cause different reactions, ranging from cutaneous, localized, and self-limited to serious systemic or fatal ones, depending on the envenoming species. Several first aid treatments are used to manage such stings but few have evidence behind their use. Read More

    Hemolytic venoms from marine cnidarian jellyfish - an overview.
    J Venom Res 2014 23;5:22-32. Epub 2014 Jul 23.
    Department of Earth, Environment and Life Sciences, University of Genova, I-16132 Genova, Italy.
    Cnidarian jellyfish are viewed as an emergent problem in several coastal zones throughout the world. Recurrent outbreaks pose a serious threat to tourists and bathers, as well as to sea-workers, involving health and economical aspects. As a rule, cnidarian stinging as a consequence of nematocyst firing induces merely local symptoms but cardiovascular or neurological complications can also occur. Read More

    Digital ischaemia: a rare but severe complication of jellyfish sting.
    Hong Kong Med J 2014 Oct;20(5):460-3
    Division of Hand and Microsurgery, Department of Orthopaedics, Prince of Wales Hospital, Shatin, Hong Kong.
    We report a case of digital ischaemia in a 31-year-old man who presented with sudden hand numbness, swelling, and cyanosis 4 days after a jellyfish sting. This is a rare complication of jellyfish sting, characterised by a delayed but rapid downhill course. Despite serial monitoring with prompt fasciotomy and repeated debridement, he developed progressive ischaemia in multiple digits with gangrenous change. Read More

    Vinegar and Chironex fleckeri stings - reply.
    Diving Hyperb Med 2014 Jun;44(2):102-3
    Emergency Department Cairns Base Hospital and Australian Institute of Tropical Health and Medicine; School of Public Health and Tropical Medicine, Centre for Biodiscovery and Molecular Development of Therapeutics, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Queensland, Australia.

    An in-vitro examination of the effect of vinegar on discharged nematocysts of Chironex fleckeri.
    Diving Hyperb Med 2014 Mar;44(1):30-4
    Queensland Emergency Medical Research Foundation (QEMRF), Queensland Tropical Health Alliance, School of Public Health and Tropical Medicine, Centre for Biodiscovery and Molecular Development of Therapeutics, Faculty of Medicine, Health and Molecular Sciences, James Cook University, Queensland, Australia.
    Objective: To determine the effect acetic acid (vinegar) has on discharged nematocysts in a simulated sting from Chironex fleckeri.

    Method: This research was performed in 2 parts: 1 C. fleckeri tentacles placed on amniotic membrane were electrically stimulated, and venom washings collected before and after application of vinegar. Read More

    Identification of two novel cytolysins from the hydrozoan Olindias sambaquiensis (Cnidaria).
    J Venom Anim Toxins Incl Trop Dis 2014 Mar 25;20(1):10. Epub 2014 Mar 25.
    São Paulo Experimental Coast Campus, São Paulo State University (UNESP - Univ Estadual Paulista), São Vicente, São Paulo State, Brazil.
    Background: Although the hydrozoan Olindias sambaquiensis is the most common jellyfish associated with human envenomation in southeastern and southern Brazil, information about the composition of its venom is rare. Thus, the present study aimed to analyze pharmacological aspects of O. sambaquiensis venom as well as clinical manifestations observed in affected patients. Read More

    Ocean enemy's lasting sting: chronic cutaneous reaction after Cnidarian attack.
    J R Nav Med Serv 2013 ;99(3):169-70
    Department of Plastic Surgery, University Hospitals Birmingham NHS Foundation Trust.
    Cnidaria stings cause a wide range of cutaneous and systemic symptoms, normally occurring shortly after the venomous insult (1). We report a case of worsening cutaneous reaction over an eight-year period following a Cnidaria attack sustained whilst maritime swimming. The lesion was characterised by severe, ulcerating chronic inflammation that required wide local excision and skin grafting. Read More

    Detection of microvasculature alterations by synchrotron radiation in murine with delayed jellyfish envenomation syndrome.
    Toxicon 2014 Apr 6;81:48-53. Epub 2014 Feb 6.
    Department of Marine Biotechnology, Faculty of Naval Medicine, Second Military Medical University, Shanghai 200433, China. Electronic address:
    Using the tentacle extract (TE) from the jellyfish Cyanea capillata, we have previously established a delayed jellyfish envenomation syndrome (DJES) model, which is meaningful for clinical interventions against jellyfish stings. However, the mechanism of DJES still remains unclear. Thus, this study aimed to explore its potential mechanism by detecting TE-induced microvasculature alterations in vivo and ex vivo. Read More

    Box jellyfish envenomation: case report of effective lemon and oil emulsion treatment.
    Trop Doct 2014 Apr 11;44(2):106-7. Epub 2013 Dec 11.
    Medical Student, Loma Linda University School of Medicine, USA.
    Box jellyfish are highly venomous and numerous possible treatments for envenomation have already been reported in the published literature. The hand of a 55-year-old scuba diver was stung in the Gulf of Guinea resulting in two crops of coalescing vesicles with intense pain and lymphadenopathy. Traditional therapies such as hot water, cold packs and acetic acid were ineffective. Read More

    Interventions for the symptoms and signs resulting from jellyfish stings.
    Cochrane Database Syst Rev 2013 Dec 9(12):CD009688. Epub 2013 Dec 9.
    Sydney School of Medicine, The University of Sydney, Edward Ford Building, A27, Sydney, NSW, Australia, 2006.
    Background: Jellyfish envenomations are common amongst temperate coastal regions and vary in severity depending on the species. Stings result in a variety of symptoms and signs, including pain, dermatological reactions and, in some species, Irukandji syndrome (including abdominal/back/chest pain, tachycardia, hypertension, sweating, piloerection, agitation and sometimes cardiac complications). Many treatments have been suggested for the symptoms and signs of jellyfish stings. Read More

    Biology and ecology of Irukandji jellyfish (Cnidaria: Cubozoa).
    Adv Mar Biol 2013 ;66:1-85
    CSIRO Marine and Atmospheric Research, Castray Esplanade, Hobart, Tasmania, Australia. Electronic address:
    Irukandji stings are a leading occupational health and safety issue for marine industries in tropical Australia and an emerging problem elsewhere in the Indo-Pacific and Caribbean. Their mild initial sting frequently results in debilitating illness, involving signs of sympathetic excess including excruciating pain, sweating, nausea and vomiting, hypertension and a feeling of impending doom; some cases also experience acute heart failure and pulmonary oedema. These jellyfish are typically small and nearly invisible, and their infestations are generally mysterious, making them scary to the general public, irresistible to the media, and disastrous for tourism. Read More

    In vitro effects on human heart and skeletal cells of the venom from two cubozoans, Chironex fleckeri and Carukia barnesi.
    Toxicon 2013 Dec 29;76:310-5. Epub 2013 Oct 29.
    Emergency Department, Cairns Base Hospital, Cairns 4870, Australia; Queensland Tropical Health Alliance (QTHA), James Cook University, McGregor Road, Cairns 4878, Australia; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, McGregor Road, Cairns 4878, Australia. Electronic address:
    Although Chironex fleckeri and Carukia barnesi cause significant human envenomation, research into their effects in human models or human cells has been limited. In this in vitro study we have presented data that shows that although C. fleckeri is highly cytotoxic to human cardiac and skeletal muscle cells, C. Read More

    [Marine envenomation by box-jellyfish in a tourist in Cambodia].
    Bull Soc Pathol Exot 2013 Oct 26;106(4):229-32. Epub 2013 Sep 26.
    Service des maladies infectieuses et tropicales, Groupe hospitalier Pitié-Salpêtrière, Paris, France.
    We report a case of box-jellyfish related envenomation in a 40 year old tourist that occurred in Sihanoukville, Cambodia, in the Gulf of Thailand. Symptoms that appeared within a few minutes associated intense pain, hand edema and large edematous and erythematous flagellations in the stung skin areas. Antibiotics and corticosteroids were delivered. Read More

    Clinical marine toxicology: a European perspective for clinical toxicologists and poison centers.
    Toxins (Basel) 2013 Aug 2;5(8):1343-52. Epub 2013 Aug 2.
    Centre Antipoison, Hôpital Sainte Marguerite, 270 Boulevard Sainte Marguerite, Marseille 13009, France.
    Clinical marine toxicology is a rapidly changing area. Many of the new discoveries reported every year in Europe involve ecological disturbances--including global warming--that have induced modifications in the chorology, behavior, and toxicity of many species of venomous or poisonous aquatic life including algae, ascidians, fish and shellfish. These changes have raised a number of public issues associated, e. Read More

    Mitochondrial dysfunction contributes to the cytotoxicity induced by tentacle extract from the jellyfish Cyanea capillata in rat renal tubular epithelial NRK-52E cells.
    Toxicon 2013 Nov 2;74:1-7. Epub 2013 Aug 2.
    Department of Marine Biotechnology, Faculty of Naval Medicine, Second Military Medical University, Shanghai 200433, China.
    Our previous studies have shown that tentacle extract (TE) from the jellyfish Cyanea capillata could induce a delayed jellyfish envenomation syndrome with severe multiple organ dysfunctions, among which renal injury with tubular necrosis seemed to be most serious. So, in this study, we aimed to explore the toxic effect of TE on rat renal tubular epithelial NRK-52E cells. Based on the previous findings that TE could cause oxidative damage in erythrocytes, the effects of TE on cell oxidative stress conditions, including ROS production and lipid peroxidation, and mitochondrial dysfunction associated with cell death were investigated in NRK-52E cells. Read More

    An outbreak of Portuguese man-of-war (Physalia physalis - Linnaeus, 1758) envenoming in Southeastern Brazil.
    Rev Soc Bras Med Trop 2013 Sep-Oct;46(5):641-4
    Introduction: Portuguese man-of-war, Physalia physalis (Linnaeus, 1758), are cnidarians capable of discharging intracellular organelles filled with venom, resulting in severe envenomation in humans.

    Methods: We report the clinical and therapeutic aspects of 331 accidents involving Portuguese man-of-war in an outbreak on the coast of the State of São Paulo, Brazil.

    Results: The clinical manifestations of envenomation were rare and mild and mostly local, systemic reactions; there was a low rate of late complications. Read More

    Long-term analysis of Irukandji stings in Far North Queensland.
    Diving Hyperb Med 2013 Mar;43(1):9-15
    School of Marine and Tropical Biology, James Cook University, Australia.
    Introduction: We reviewed the occurrence, trends, definition and severity of the Irukandji syndrome for the Cairns region of North Queensland, Australia.

    Methods: A retrospective analysis of patient files from two sources was conducted: historic accounts kept by Dr Jack Barnes for the period 1942 to 1967, and records from the Emergency Unit in Cairns Base Hospital for 1995 to 2007.

    Results: There has been a significant increase in the length of the Irukandji season since it was first reliably recorded (15 days in 1961; 151 days in 2002); however, annual numbers of envenomations were highly variable. Read More

    Jellyfish stings and their management: a review.
    Mar Drugs 2013 Feb 22;11(2):523-50. Epub 2013 Feb 22.
    Department of Molecular Medicine, Padua University, Padua 35128, Italy.
    Jellyfish (cnidarians) have a worldwide distribution. Despite most being harmless, some species may cause local and also systemic reactions. Treatment of jellyfish envenomation is directed at: alleviating the local effects of venom, preventing further nematocyst discharges and controlling systemic reactions, including shock. Read More

    Irukandji syndrome: a widely misunderstood and poorly researched tropical marine envenoming.
    Diving Hyperb Med 2012 Dec;42(4):214-23
    School of Marine and Tropical Biology, James Cook University, Australia.
    Irukandji syndrome is a poorly defined set of symptoms that occur after envenoming by certain species of jellyfish, primarily cubozoans or 'box jellyfish'. Envenomed victims can show symptoms ranging from headaches, severe pain, nausea and vomiting to pulmonary oedema, cardiac failure and severe hypertension resulting in death. Historically, this syndrome appears to have been misdiagnosed and reported cases are undoubtedly a significant underestimation of the prevalence of this syndrome. Read More

    An unusual marine envenomation following a rope contact: a report on nine cases of dermatitis caused by Pennaria disticha.
    Toxicon 2013 Jan 19;61:125-8. Epub 2012 Nov 19.
    Family Medicine, American Hospital, Istanbul, Turkey.
    We would like to present the clinical course of nine patients who had an acute, painful dermatitis following contact with a rope used as a swimming area liner in the sea. The macroscopic and microscopic analysis of the fouling on the rope retrospectively, revealed Pennaria disticha as the causative organism. To our knowledge, there is no previous report on P. Read More

    Exploiting the nephrotoxic effects of venom from the sea anemone, Phyllodiscus semoni, to create a hemolytic uremic syndrome model in the rat.
    Mar Drugs 2012 Jul 23;10(7):1582-604. Epub 2012 Jul 23.
    Renal Replacement Therapy, Division of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
    In the natural world, there are many creatures with venoms that have interesting and varied activities. Although the sea anemone, a member of the phylum Coelenterata, has venom that it uses to capture and immobilise small fishes and shrimp and for protection from predators, most sea anemones are harmless to man. However, a few species are highly toxic; some have venoms containing neurotoxins, recently suggested as potential immune-modulators for therapeutic application in immune diseases. Read More

    Portuguese man-of-war (Physalia physalis) envenomation on the Aquitaine Coast of France: an emerging health risk.
    Clin Toxicol (Phila) 2012 Aug 11;50(7):567-70. Epub 2012 Jul 11.
    Centre Antipoison, Place Amélie Raba Léon, Bordeaux, France.
    Context: The Portuguese man-o-war is a cnidaria classically found in tropical waters. It can cause serious and even life-threatening envenomation in swimmers, surfers and seafarers. Presence of the Atlantic species Physalia physalis has long been reported in European coastal waters but was always an exceptional event. Read More

    Review of fatal and severe cases of box jellyfish envenomation in Thailand.
    Asia Pac J Public Health 2015 Mar 28;27(2):NP1639-51. Epub 2012 Jun 28.
    Ministry of Public Health, Muang, Nonthaburi, Thailand.
    The study aimed to describe severe and fatal cases of box jellyfish stings in Thailand. Medical records were reviewed and patients, relatives, health staffs, and witnesses were interviewed. The pictures of suspected box jellyfish were sent via e-mail to experts in the toxic jellyfish network for further identification. Read More

    Evidence-based treatment of jellyfish stings in North America and Hawaii.
    Ann Emerg Med 2012 Oct 6;60(4):399-414. Epub 2012 Jun 6.
    Department of Emergency Medicine, Division of Medical Toxicology, UCSD Medical Center, University of California, San Diego, San Diego, CA, USA.
    We performed a systematic review of the evidence supporting various treatments for envenomation by jellyfish (cnidarian) and related organisms in North America and Hawaii. Our review produced 19 pertinent primary articles. Current research demonstrates variable response to treatment, often with conflicting results according to species studied, which contributes to considerable confusion about what treatment is warranted and efficacious. Read More

    Australian carybdeid jellyfish causing "Irukandji syndrome".
    Toxicon 2012 May 14;59(6):617-25. Epub 2012 Feb 14.
    Intensive Care Unit, Royal Children's Hospital, Flemington Road, Parkville 3052, Australia.
    The Australian carybdeid jellyfish associated with Irukandji syndrome is Carukia barnesi, (Barnes' jellyfish). Other Australian carybdeid jellyfish that may be associated with the syndrome include Carukia shinju, Carybdea xaymacana, Malo maxima, Malo kingi, Alatina mordens, Gerongia rifkinae, and Morbakka fenneri ("Morbakka"). These small jellyfish are difficult to capture and identify. Read More

    Neurotoxin localization to ectodermal gland cells uncovers an alternative mechanism of venom delivery in sea anemones.
    Proc Biol Sci 2012 Apr 2;279(1732):1351-8. Epub 2011 Nov 2.
    Department of Molecular Biology and Ecology of Plants, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, 69978 Tel Aviv, Israel.
    Jellyfish, hydras, corals and sea anemones (phylum Cnidaria) are known for their venomous stinging cells, nematocytes, used for prey and defence. Here we show, however, that the potent Type I neurotoxin of the sea anemone Nematostella vectensis, Nv1, is confined to ectodermal gland cells rather than nematocytes. We demonstrate massive Nv1 secretion upon encounter with a crustacean prey. Read More

    Irukandji sydrome in the Torres Strait: a series of 8 cases.
    Wilderness Environ Med 2011 Dec 14;22(4):338-42. Epub 2011 Oct 14.
    Thursday Island Hospital, Torres Strait and Northern Peninsula Area Health Service, Far North Queensland, North Queensland, Australia.
    Objective: To review the presentations of a series of patients with suspected Irukandji syndrome in the Torres Strait, where the syndrome has hitherto been unknown or undocumented, in order to identify at-risk groups and improve the management of this condition in the region.

    Methods: A mixed retrospective-prospective review of eight cases of patients with suspected Irukandji syndrome in the Torres Strait, with a focus on the differences between the clinical presentations and patient outcomes.

    Results: Irukandji syndrome is the most likely explanation, based on current knowledge, of this series of marine envenomation syndromes in the Torres Strait. Read More

    Target organ identification of jellyfish envenomation using systemic and integrative analyses in anesthetized dogs.
    J Pharmacol Toxicol Methods 2011 Sep-Oct;64(2):173-9. Epub 2011 Jul 29.
    Department of Pharmacology and Toxicology, College of Veterinary Medicine, Gyeongsang National University, Jinju, 660-701, South Korea.
    Proper treatment of jellyfish envenomed patients can be successfully achieved only from an understanding of the overall functional changes and alterations in physiological parameters under its envenomation. The majority of previous investigations on jellyfish venoms have covered only a couple of parameters at a time. Unlike most other fragmentary jellyfish studies, we employed an integrative toxicological approach, including hemodynamics, clinical chemistry and hematology analyses, using N. Read More

    Conus magus vs. Irukandji syndrome: a computational approach of a possible new therapy.
    Brain Res Bull 2011 Oct 12;86(3-4):195-202. Epub 2011 Jul 12.
    Department of Food Science, Sapientia Hungarian University of Transylvania, Miercurea Ciuc, Romania.
    The Irukandji syndrome is caused by the sting of some small jellyfish species. The syndrome has severe life-threatening consequences. The exacerbating pain and cardiovascular symptoms (tachycardia and hypertension) are hard to control in many cases. Read More

    Fatal and severe box jellyfish stings, including Irukandji stings, in Malaysia, 2000-2010.
    J Travel Med 2011 Jul-Aug;18(4):275-81. Epub 2011 Jun 15.
    Divers Alert Network Asia-Pacific, Ashburton, Melbourne, VIC 3147, Australia.
    Background: Jellyfish are a common cause of injury throughout the world, with fatalities and severe systemic events not uncommon after tropical stings. The internet is a recent innovation to gain information on real-time health issues of travel destinations, including Southeast Asia.

    Methods: We applied the model of internet-based retrospective health data aggregation, through the Divers Alert Network Asia-Pacific (DAN AP), together with more conventional methods of literature and media searches, to document the health significance, and clinical spectrum, of box jellyfish stings in Malaysia for the period January 1, 2000 to July 30, 2010. Read More

    Bluebottle envenomation-induced crystalline keratopathy.
    Cornea 2011 Jul;30(7):835-7
    Department of Pathology, School of Medical Sciences, University of New South Wales, Sydney, Australia.
    Purpose: To report a patient who developed a crystalline keratopathy after bluebottle envenomation of the cornea.

    Method: Case report with histopathological correlation and literature review.

    Results: A 61-year-old man presented to the Ophthalmology clinic after he was stung in the left eye by a bluebottle while swimming in the sea. Read More

    Biological activity of sea anemone proteins: I. Toxicity and histopathology.
    Indian J Exp Biol 2010 Dec;48(12):1225-32
    Centre of Advanced Study in Marine Biology, Annamalai University, Portonovo 608 502, India.
    The crude as well as partially purified protein fractions from anemone species viz. Heteractis magnifica, Stichodactyla haddoni and Paracodylactis sinensis, collected from the Gulf of Mannar, south east coast of India were found to be toxic at different levels to mice. The mice showed behavioral changes such as loss of balance, opaque eyes, tonic convulsions, paralysis, micturiction, flexing of muscles, prodding (insensitive to stimulii), foaming from mouth and exophthalmia. Read More

    Mediterranean jellyfish venoms: a review on scyphomedusae.
    Mar Drugs 2010 Apr 4;8(4):1122-52. Epub 2010 Apr 4.
    Dipartimento di Biologia, Università di Genova, Viale Benedetto XV 5, I-16132, Genova, Italy.
    The production of natural toxins is an interesting aspect, which characterizes the physiology and the ecology of a number of marine species that use them for defence/offence purposes. Cnidarians are of particular concern from this point of view; their venoms are contained in specialized structures--the nematocysts--which, after mechanical or chemical stimulation, inject the venom in the prey or in the attacker. Cnidarian stinging is a serious health problem for humans in the zones where extremely venomous jellyfish or anemones are common, such as in temperate and tropical oceanic waters and particularly along several Pacific coasts, and severe cases of envenomation, including also lethal cases mainly induced by cubomedusae, were reported. Read More

    Tropical dermatology: marine and aquatic dermatology.
    J Am Acad Dermatol 2009 Nov;61(5):733-50; quiz 751-2
    Department of Dermatology at Universidade Estadual Paulista, Botucatu, Vital Brazil Hospital, Instituto Butantan and Marine School of Biology, São Paulo State, São Paulo, Brazil.
    Unlabelled: Dermatoses caused by marine organisms are frequently seen in dermatology clinics worldwide. Cutaneous injuries after exposure to marine environments include bacterial and fungal infections and lesions caused by aquatic plants and protists. Some of these diseases are well known by dermatologists, such as Vibrio vulnificus septicemia and erysipeloid, but others are uncommon, such as envenomation caused by ingestion or contact with certain dinoflagellates or cyanobacteria, which are associated with rashes that can begin within minutes after exposure. Read More

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