4,351 results match your criteria Clubfoot


Talipes Equinus Deformity Caused by Fibrous Gastrocnemius Muscle Contracture After Direct Contusion in Football Players: Report of Two Cases.

J Foot Ankle Surg 2020 Jul - Aug;59(4):816-820

Professor, Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.

Two main causes of gastrocnemius contracture have been considered: 1) congenital deformities in pediatric patients, such as limb-length discrepancy, cerebral palsy, flatfoot, and clubfoot; and 2) secondary conditions such as immobilization for trauma or a nonfunctional limb. Talipes equinus deformity caused by fibrous gastrocnemius contracture after a direct muscle contusion is extremely rare. We describe 2 cases of talipes equinus deformity caused by fibrous gastrocnemius muscle contracture after a direct contusion in football players. Read More

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http://dx.doi.org/10.1053/j.jfas.2019.10.004DOI Listing

Mandibular-Pelvic-Patellar syndrome (MPP) is a novel PITX1-related disorder due to alteration of PITX1 transactivation ability.

Hum Mutat 2020 Jun 29. Epub 2020 Jun 29.

Service de génétique, Centre de Référence Anomalies du Développement et Centre de Compétences Maladies Osseuses Constitutionnelles, Hospices Civils de Lyon, Bron, France.

PITX1 is a homeobox transcription factor essential for hindlimb morphogenesis. Two PITX1-related human disorders have been reported to date: PITX1 ectopic expression causes Liebenberg syndrome, characterized by malformation of upper limbs showing a "lower limb" appearance; PITX1 deletions or missense variation cause a syndromic picture including clubfoot, tibial hemimelia and preaxial polydactyly. We report two novel PITX1 missense variants, altering PITX1 transactivation ability, in three individuals from two unrelated families showing a distinct recognizable autosomal dominant syndrome, including first branchial arch, pelvic, patellar and male genital abnormalities. Read More

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http://dx.doi.org/10.1002/humu.24070DOI Listing

Associated anomalies in cases with congenital clubfoot.

Am J Med Genet A 2020 Jun 26. Epub 2020 Jun 26.

Laboratoire de Génétique Médicale, Faculté de Médecine, Strasbourg cedex, France.

Congenital clubfoot CTEV is a common congenital anomaly, its etiology is unclear and its pathogenesis is controversial. Cases with CTEV often have other non-CTEV associated congenital anomalies. The purpose of this study was to assess the prevalence and the types of these associated anomalies in a defined population. Read More

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http://dx.doi.org/10.1002/ajmg.a.61721DOI Listing

Resistive index and peak systolic velocity for congenital talipes equinovarus: A color Doppler ultrasonography study.

Jt Dis Relat Surg 2020 26;31(2):169-174. Epub 2020 Mar 26.

Harran Üniversitesi Tıp Fakültesi Ortopedi ve Travmatoloji Anabilim Dalı, 63300 Şanlıurfa, Türkiye.

Objectives: This study aims to investigate whether resistive index (RI) and peak systolic velocity (PSV) are suitable parameters to determine if a clubfoot differs from feet of the normal population.

Patients And Methods: Fifty-four feet of 27 clubfoot patients (22 males, 5 females; mean age 30.4±16. Read More

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http://dx.doi.org/10.5606/ehc.2020.72283DOI Listing

The role of clubfoot training programmes in low- and middle-income countries: a systematic review.

Trop Doct 2020 Jun 23:49475520931343. Epub 2020 Jun 23.

Professor, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK.

While adoption of the Ponseti method has continued gradually, its use to manage patients with congenital talipes equinovarus (CTEV) has been limited in low- and middle-income countries (LMICs) for a number of reasons including a lack of clinical training on technique and lack of appropriate clinical equipment. There are a frequent number of emerging studies that report on the role of clubfoot training programmes; however, little is known in regard to cumulative benefits. A systematic review was undertaken through Medline, the Cochrane Library and Web of Science for studies analysing clubfoot training programmes. Read More

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http://dx.doi.org/10.1177/0049475520931343DOI Listing
June 2020
0.528 Impact Factor

Treatment for Clubfoot: Stockinette Versus Webril Cast Padding in the Ponseti Method.

J Pediatr Orthop 2020 Jun 19. Epub 2020 Jun 19.

Division of Orthopaedic Surgery, Children's Hospital of Eastern Ontario, Ottawa, ON.

Background: The Ponseti method of serial manipulation and casting revolutionized the treatment of one of the most common congenital orthopaedic conditions-clubfoot-resulting in less surgical morbidity and better functional results. Several studies have examined aspects of nonoperative treatment but none have explored the effect of different types of undercast padding.

Methods: The authors performed a randomized controlled trial comparing cotton Stockinette and Webril undercast padding using the Ponseti method. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001617DOI Listing

Successful Ponseti-treated Clubfeet at Age 2 Years: What is the Rate of Surgical Intervention After This?

J Pediatr Orthop 2020 Jun 17. Epub 2020 Jun 17.

Texas Scottish Rite Hospital for Children, Dallas, Texas.

Background: In recent decades, nonoperative Ponseti casting has become the standard of care in the treatment of idiopathic clubfoot. However, the rate of recurrence, even after successful Ponseti treatment is not insignificant. The purpose of this study was to determine the future rate, timing, and type of surgery needed in patients whose idiopathic clubfeet treated by Ponseti casting were considered successful at the age of 2 years. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001614DOI Listing

Global prevalence estimates of three chronic musculoskeletal conditions: club foot, juvenile idiopathic arthritis and juvenile systemic lupus erythematosus.

Pediatr Rheumatol Online J 2020 Jun 12;18(1):49. Epub 2020 Jun 12.

Population Health Sciences Institute, Newcastle University, The Medical School, Framlington Place, Newcastle upon Tyne, Tyne and Wear, NE24HH, UK.

Background: Musculoskeletal (MSK) conditions are a major source of morbidity and disability. There is a lack of global comparable data on the burden of MSK conditions in children and young people. Our aim was to estimate the global prevalence of three MSK conditions - Talipes Equinovarus (Clubfoot), Juvenile Idiopathic Arthritis (JIA) and Juvenile Systemic Lupus Erythematosus (JSLE). Read More

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http://dx.doi.org/10.1186/s12969-020-00443-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291758PMC

Rare and duplications containing in clubfoot.

J Med Genet 2020 Jun 9. Epub 2020 Jun 9.

Department of Neurology, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA

Introduction: Congenital clubfoot is a common birth defect that affects at least 0.1% of all births. Nearly 25% cases are familial and the remaining are sporadic in inheritance. Read More

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http://dx.doi.org/10.1136/jmedgenet-2020-106842DOI Listing

What a paediatrician should know about congenital clubfoot.

Ital J Pediatr 2020 Jun 4;46(1):78. Epub 2020 Jun 4.

University of Trieste, Piazzale Europa 1, Trieste, Italy.

Clubfoot is the most frequent congenital malformation of the foot, affecting more than 1-2 subjects per 1.000 newborns. Without appropriate treatment, a child with congenital clubfoot will never be able to walk physiologically with a dramatic impact on the quality of life. Read More

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http://dx.doi.org/10.1186/s13052-020-00842-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271518PMC

Talipes Equinovarus Treatment in Infants Treated by the Ponseti Method Compared With Posterior-Only Release: A Mid-Childhood Comparison of Results.

J Foot Ankle Surg 2020 May 29. Epub 2020 May 29.

Orthopedic Surgeon, Instituto Biomecánica de Valencia, Universitat Politècnica de València, València, Spain; Orthopedic Surgeon, Grupo de Tecnología Sanitaria del IBV, CIBER de Bioingeniería, Biomateriales y Nanomedicina, Valencia, Spain.

The aim of this study is to evaluate children in middle childhood with clubfoot treated with Ponseti method vs posterior-only release and to compare their results to a control group with 4 modules (physical examination, gait study, radiographic measurements, and questionnaires). From 01/01/2004 until 01/01/2009, 31 children (45 feet) were treated with the posterior-only release protocol and 22 patients (34 feet) were treated with the Ponseti method. In 2016, patients were evaluated and compared with 25 children without neuromuscular disorders. Read More

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http://dx.doi.org/10.1053/j.jfas.2018.12.046DOI Listing

Results of JESS (Joshi's External Stabilizing System) in Relapsed, Neglected and Neurogenic Clubfoot in an Age Group of 2-10 Years.

Ortop Traumatol Rehabil 2020 Apr;22(2):121-129

Postgraduate Department of Orthopaedics Hospital For Bone and Joint Surgery Government Medical College Srinagar, Kashmir, India.

Background: Joshi's External Stabilization System (JESS) is an external fixator based methodology to correct different deformities of club foot using differential distraction.

Material And Methods: 31 difficult clubfeet feet in 24 patients who were neglected, neurogenic or relapsed were treated using JESS between July 2013 to June 2015 with an average follow-up of 4. 2 years. Read More

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http://dx.doi.org/10.5604/01.3001.0014.1170DOI Listing

Does generalized joint hypermobility influence the Ponseti treatment of clubfoot patients?

J Pediatr Orthop B 2020 May 22. Epub 2020 May 22.

David Geffen School of Medicine.

Objectives: Previous investigators have suggested a role for generalized joint hypermobility (GJH) in the etiology of clubfoot deformity, while others have suggested its presence may influence treatment outcomes. We sought to determine if GJH was associated with the demographics, treatment, or propensity to relapse of patients whose clubfeet were managed using the Ponseti method.

Methods: Fifty-seven patients with Ponseti-treated clubfeet comprised the cohort; median age 61 months (range, 38-111 months). Read More

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http://dx.doi.org/10.1097/BPB.0000000000000747DOI Listing

Plantar Pressure Distribution of Right and Left Foot in Bilateral Clubfoot Treated by Ponseti Method: A Correlation Analysis.

Med Sci Monit 2020 May 22;26:e921990. Epub 2020 May 22.

Department of Orthopedics, Xijing Hospital, The Air Force Medical University, Xi'an, Shaanxi, China (mainland).

BACKGROUND Congenital clubfoot is a common pediatric orthopedic deformity that can be corrected by Ponseti method, and pedobarographic analysis has been used to assess the outcomes. However, the relationship between the plantar pressure distribution of the right and left foot in children with bilateral clubfoot has not been studied. In this study, the pedobarographic data of patients with bilateral clubfoot who were treated by the Ponseti method were reviewed, and a correlation analysis was conducted to clarify the relationship between the right and left foot. Read More

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http://dx.doi.org/10.12659/MSM.921990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261003PMC

Remote monitoring of clubfoot treatment with digital photographs in low resource settings: Is it accurate?

PLoS One 2020 15;15(5):e0232878. Epub 2020 May 15.

Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom.

Background: Clinical examination and functional assessment are often the first steps to assess outcome of clubfoot treatment. Clinical photographs may be an adjunct used to assess treatment outcomes in lower resourced settings where physical review by a specialist is limited. We aimed to evaluate the diagnostic performance of photographic images of patients with clubfoot in assessing outcome following treatment. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0232878PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228114PMC

Interventions for congenital talipes equinovarus (clubfoot).

Cochrane Database Syst Rev 2020 05 15;5:CD008602. Epub 2020 May 15.

Department of Health Professions, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Background: Congenital talipes equinovarus (CTEV), also known as clubfoot, is a common congenital orthopaedic condition characterised by an excessively turned-in foot (equinovarus) and high medial longitudinal arch (cavus). If left untreated it can result in long-term disability, deformity and pain. Interventions can be conservative (such as splinting or stretching) or surgical. Read More

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http://dx.doi.org/10.1002/14651858.CD008602.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265154PMC

Guided Growth for Ankle Valgus Deformity: The Challenges of Hardware Removal.

J Pediatr Orthop 2020 May 8. Epub 2020 May 8.

Department of Pediatric Orthopedic Surgery, Shriners Hospitals for Children, Greenville, SC.

Background: Ankle valgus deformity is associated with conditions such as clubfoot, cerebral palsy, and myelodysplasia. Guided growth strategies using a transphyseal screw provide effective correction of ankle valgus deformity. When correction occurs before skeletal maturity, screw removal is required to prevent overcorrection in the coronal plane. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001583DOI Listing

Correction of the Neglected Clubfoot in the Adolescent and Adult Patient.

Foot Ankle Clin 2020 Jun;25(2):205-220

Alder Hey Children's Hospital, East Prescot Road, Liverpool L14 5AB, UK.

Clubfoot is a complex 4-dimensional deformity involving the hindfoot, midfoot, and forefoot. The fourth dimension is time. Treatment aims at achieving a pain-free, plantigrade, and mobile foot but, over time, flexible deformities become fixed and more difficult to manage. Read More

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http://dx.doi.org/10.1016/j.fcl.2020.02.008DOI Listing

Managing Severe Foot and Ankle Deformities in Global Humanitarian Programs.

Foot Ankle Clin 2020 Jun 2;25(2):183-203. Epub 2020 Apr 2.

Steps2Walk, 1209 Harbor Island Walk, Baltimore, MD 21230, USA. Electronic address:

The severe foot and ankle deformities the authors' organization has encountered in humanitarian programs worldwide are more complicated than those surgeons treat in daily practice in developed countries. Severity of deformity, patients' economic limitations, patients' expectations and realistic needs in life, availability of surgical instrumentation, the local team's understanding of foot and ankle surgery and their ability to do consultation for patients postoperatively, and compliance of patients all account for success of the surgery. Regardless of the effort surgeons make, complications and recurrence occur. Read More

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http://dx.doi.org/10.1016/j.fcl.2020.01.001DOI Listing

Increased Microvessel and Arteriole Density in the Contracted Side of the Relapsed Clubfoot.

J Pediatr Orthop 2020 May 5. Epub 2020 May 5.

Institute of Physiology of the Czech Academy of Sciences.

Background: Clubfoot deformity (pes equinovarus) is one of the most common birth defects, and its etiology is still unknown. Initial clubfoot treatment is based on the Ponseti method throughout most of the world. Despite the effectiveness of this therapy, clubfoot may relapse. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001563DOI Listing

Clinical outcomes of iatrogenic complex clubfoot treated with modified Ponseti method.

Int Orthop 2020 May 6. Epub 2020 May 6.

Private Office Pediatric Orthopaedics, Yıldızposta Cad. Emekli Subayevleri, 34. Blok, Daire: 1, İstanbul, Turkey.

Introduction: There are not enough studies demonstrating the results of the modified Ponseti method on iatrogenic complex clubfoot that occurs due to errors during the application of the method for treating idiopathic clubfoot. The present study aimed to present the treatment results of the modified method reported by Ponseti for treating feet that became complex solely due to errors during casting.

Methods: Patients with the confirmed diagnosis of iatrogenic complex clubfoot were according to initial physicians' report and photographs were included in this retrospective case series study. Read More

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http://dx.doi.org/10.1007/s00264-020-04529-6DOI Listing

The influence of laterality, sex and family history on clubfoot severity.

J Child Orthop 2020 Apr;14(2):145-150

Department of Paediatric Orthopaedics, Anna Meyer Children's Hospital, Florence, Italy.

Purpose: Epidemiological studies on idiopathic clubfeet have shown a typical distribution consistent across ethnic groups: bilaterality in about 50% of cases and a male to female ratio of 2:1. Whether this corresponds also to differences in severity according to laterality and sex has been poorly evaluated. As well, the correlation between family history and severity has not been previously investigated. Read More

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http://dx.doi.org/10.1302/1863-2548.14.190184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184649PMC

Prenatal clubfoot increases the risk for clinically significant chromosomal microarray results - Analysis of 269 singleton pregnancies.

Early Hum Dev 2020 Jun 20;145:105047. Epub 2020 Apr 20.

Genetics Institute, Carmel Medical Center, affiliated to the Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel. Electronic address:

Objective: To examine the detection rate of clinically significant chromosomal microarray analysis (CMA) results in singleton pregnancies with clubfoot.

Methods: Data from all CMA tests in singleton pregnancies with sonographic diagnosis of clubfoot (talipes equinovarus) performed between January 2013 and September 2017 were retrospectively obtained from the Israeli Ministry of Health computerized database. The rates of clinically significant CMA results in fetuses with clubfoot were compared to the general population risk, based on a local cohort of 5541 pregnancies with no major sonographic anomalies. Read More

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http://dx.doi.org/10.1016/j.earlhumdev.2020.105047DOI Listing

Preference-based measures of health-related quality of life in congenital mobility impairment: a systematic review of validity and responsiveness.

Health Econ Rev 2020 Apr 21;10(1). Epub 2020 Apr 21.

School of Health Sciences, Fron Heulog, Bangor University, Gwynedd, LL57 2EF, Wales, UK.

Introduction: Mobility impairment is the leading cause of disability in the UK. Individuals with congenital mobility impairments have unique experiences of health, quality of life and adaptation. Preference-based outcomes measures are often used to help inform decisions about healthcare funding and prioritisation, however the applicability and accuracy of these measures in the context of congenital mobility impairment is unclear. Read More

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http://dx.doi.org/10.1186/s13561-020-00270-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175543PMC

The Influence of Achilles Tenotomy and Compliance with Foot Abduction Orthosis on the Relapse Rate of Ponseti Treatment for Idiopathic Clubfoot: A Regional Study.

J Foot Ankle Surg 2020 Jul - Aug;59(4):784-787. Epub 2020 Apr 16.

Professor, Pediatric Division, Soroka Medical Center, Ben Gurion University Beer-Sheva, Israel.

The Ponseti method for treating idiopathic clubfoot is based on gradual manipulations and corrective plaster castings followed by a years-long period of use of a foot orthosis. The role of surgery is limited. The factors that may affect outcome and their influence are subject of controversy. Read More

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http://dx.doi.org/10.1053/j.jfas.2019.12.007DOI Listing

A retrospective study of idiopathic clubfoot managed by Ponseti method using Pirani and Dimeglio scoring, in Indian population: a minimum 3-year follow-up.

J Pediatr Orthop B 2020 Apr 13. Epub 2020 Apr 13.

Department of Pediatric Orthopaedics, Indraprastha Apollo Hospital, New Delhi, India.

Congenital talipo-equino-varus (CTEV) is one of the most common congenital deformities affecting children in India with an incidence of 1.19/1000 live births. Ponseti treatment regimen has been established as the gold standard of care for idiopathic clubfoot. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000728DOI Listing

Influence of Beginning Time of Casting for Clubfoot Treatment by Ponseti Method in Different Age Group Infants: A Retrospective Study.

Indian J Orthop 2020 Feb 24;54(1):55-59. Epub 2020 Jan 24.

Department of Orthopaedics, S N Medical College, Jodhpur, India.

Background: The clubfoot is one of the commonly found congenital deformities in newborn. The Ponseti method is the most effective nonoperative clubfoot management method. It is based on understanding of pathoanatomy of clubfoot. Read More

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http://dx.doi.org/10.1007/s43465-019-00004-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093653PMC
February 2020
0.624 Impact Factor

Use of PROMIS in Assessment of Children With Ponseti-treated Idiopathic Clubfoot: Better Scores With Greater Than 3 Years of Brace Use.

J Pediatr Orthop 2020 Mar 31. Epub 2020 Mar 31.

Orthopaedics, Shriners Hospitals for Children-Northern California, Sacramento, CA.

Background: Patient-Reported Outcomes Measurement Information System (PROMIS) is a well-validated tool used to measure health-related quality of life for children and adolescents with chronic medical conditions. The current study evaluates PROMIS scores in 3 domains for children with Ponseti-treated idiopathic clubfoot.

Methods: This is a retrospective cohort study of 77 children, ages 5 to 16 years, treated by Ponseti protocol for idiopathic clubfoot. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001556DOI Listing

Normalization of Forefoot Supination After Tibialis Anterior Tendon Transfer for Dynamic Clubfoot Recurrence.

J Pediatr Orthop 2020 Mar 20. Epub 2020 Mar 20.

Department of Paediatric Orthopaedics.

Background: We aimed to evaluate the effect of tibialis anterior tendon transfer (TATT) on foot motion in children with clubfoot recurrence after initial Ponseti treatment.

Methods: Children with dynamic clubfoot recurrence after initial Ponseti treatment who underwent TATT between 2014 and 2017 were considered for inclusion. Exclusion criteria were neurological disease, split transfer of the tendon, additional bone or joint invasive surgery, and initial treatment abroad. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001542DOI Listing

A combined method for binning coupling angles to define coordination patterns.

J Biomech 2020 Apr 3;103:109598. Epub 2020 Jan 3.

Movement Science Laboratory, Scottish Rite for Children, Dallas, TX, USA. Electronic address:

The vector coding technique has been used to quantify coordination of two joints, segments, and/or planes during cyclic activities, such as walking. Coordination patterns can be identified by categorizing the tangent lines of an angle-angle plot by their direction, termed "coupling angle binning" or "phase binning". In the literature the ranges of directions, or "bins", originally divided by Chang et al. Read More

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http://dx.doi.org/10.1016/j.jbiomech.2020.109598DOI Listing

Does an overcorrected clubfoot caused by surgery or by the Ponseti method behave differently?

Gait Posture 2020 03 19;77:308-314. Epub 2020 Feb 19.

Department of Orthopaedic Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Rathsberger Str. 57, D-91054 Erlangen, Bavaria, Germany.

Background: Overcorrection is a recognized problem following surgical treatment of congenital clubfoot. Recently this complication has also been mentioned following Ponseti treatment.

Research Question: Do overcorrected clubfeet (OCCF) caused by surgery behave differently from those caused by Ponseti treatment in terms of segmental motion of the feet and show differences in the severity of deformity on X-rays?

Methods: Children between 7 and 12 years with OCCF were included in this study. Read More

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http://dx.doi.org/10.1016/j.gaitpost.2020.02.012DOI Listing

Anterior Distal Hemiepiphysiodesis of Tibia for Treatment of Recurrent Equinus Deformity Due to Flat-Top Talus in Surgically Treated Clubfoot.

J Foot Ankle Surg 2020 Mar - Apr;59(2):418-422

Associate Professor, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Associate Professor, Imam Reza Hospital, Birjand University of Medical Sciences, Birjand, Iran.

Treatment of persistent or recurrent equinus after repeated surgical releases can be challenging in patients with clubfoot. Anterior distal tibial epiphysiodesis has recently been used in patients with recurrent progressive equinus deformity, with inconsistent outcomes. Herein, we used this technique in a carefully selected subgroup (8 children, 9 feet) of patients with a severe equinus deformity and a flat-top talus. Read More

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http://dx.doi.org/10.1053/j.jfas.2019.08.018DOI Listing
December 2018

Is the Denis Browne Splint a Myth? A Long-Term Prospective Cohort Study in Clubfoot Management using Denis Browne Splint Versus Daily Exercise Protocol.

J Foot Ankle Surg 2020 Mar - Apr;59(2):314-322

Professor, Pediatric Orthopedics & Limb Reconstructive Surgeries, Tanta University, Tanta, Egypt.

The Ponseti technique is successful in idiopathic clubfoot management. However, the leading cause of relapse and recurrence is nonadherence to the Denis Brown bracing protocol. This necessitates more extensive soft tissue surgeries. Read More

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http://dx.doi.org/10.1053/j.jfas.2019.08.026DOI Listing
December 2018
0.979 Impact Factor

Results of a Standard versus an Accelerated Ponseti Protocol for Clubfoot: A Prospective Randomized Study.

Clin Orthop Surg 2020 Mar 13;12(1):100-106. Epub 2020 Feb 13.

Postgraduate Department of Orthopaedics, Government Medical College, Srinagar, India.

Background: The aim of this study was to compare the results of the standard once-weekly Ponseti casting technique to an accelerated twice-weekly regimen in our population cohort.

Methods: A prospective randomized controlled study was conducted with a total of 100 consecutive patients (158 feet) being enrolled for the study. Fifty patients were randomized to each group and followed up for at least one year. Read More

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http://dx.doi.org/10.4055/cios.2020.12.1.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031442PMC

Combined 3D analysis of lower-limb morphology and function in children with idiopathic equinovarus clubfoot: A preliminary study.

Orthop Traumatol Surg Res 2020 Feb 26. Epub 2020 Feb 26.

Institut de biomécanique humaine Georges-Charpak, Arts et Métiers ParisTech, 75013 Paris, France.

Introduction: In children treated for idiopathic equinovarus clubfoot (EVCF), the relation between morphologic defects on clinical examination and standard X-ray on the one hand and functional abnormalities on the other is difficult to objectify. The aim of the present study was to demonstrate the feasibility of combined 3D analysis of the foot and lower limb based on biplanar EOS radiographs and gait analysis. The study hypothesis was that this provides better understanding of abnormalities in form and function. Read More

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http://dx.doi.org/10.1016/j.otsr.2019.11.013DOI Listing
February 2020

Letter to the Editor Brace compliance in clubfoot: Clinical signs.

J Clin Orthop Trauma 2020 Mar-Apr;11(2):344-346. Epub 2019 Jan 28.

Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi-31, India.

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http://dx.doi.org/10.1016/j.jcot.2019.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026544PMC
January 2019

Comparison of three different methods of anterior tibial tendon transfer for relapsed clubfoot: A pilot study.

J Clin Orthop Trauma 2020 Mar-Apr;11(2):240-244. Epub 2018 Sep 7.

Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, 110031, India.

Introduction: The commonly techniques for anterior tibial tendon transfer (ATTT) for clubfoot are split transfers (Hoffer), whole transfers to cuboid (Garceau) or 3rd cuneiform (Ponseti). We compared these surgical ATTT methods for relapsed clubfoot.

Material And Methods: Thirty relapsed clubfoot (46 feet) patients initially treated with Ponseti casting technique were prospectively randomized for ATTT techniques. Read More

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http://dx.doi.org/10.1016/j.jcot.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026582PMC
September 2018

Nwdps protocol - A simple functional outcome assessment tool for clubfoot correction and a review of literature.

J Clin Orthop Trauma 2020 Mar-Apr;11(2):236-239. Epub 2019 May 8.

Department of Paediatrics, PGIMER & Dr Ram Manohar Lohia Hospital, New Delhi, 110001, India.

Introduction: Various clubfoot severity scoring systems are known to us. Dimeglio and Pirani Scoring systems are most widely used. Also, various treatment outcome measures have been proposed by researchers to assess patient satisfaction and results of treatment. Read More

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http://dx.doi.org/10.1016/j.jcot.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026552PMC

Correlation of scores with number of Ponseti casts required for clubfoot correction in the older child.

J Clin Orthop Trauma 2020 Mar-Apr;11(2):232-235. Epub 2019 Apr 20.

Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, 110031, India.

Background: We examined the correlation between initial Pirani and Dimeglio scores and their individual components to the number of casts for older clubfoot children.

Methods: Twenty seven patients (39 feet) aged 2-11 years with idiopathic clubfeet were treated using the Ponseti technique and correlation with number of corrective casts calculated. The number of cast required was counted from application of primary cast to the time of initiation of the foot abduction orthosis. Read More

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http://dx.doi.org/10.1016/j.jcot.2019.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026520PMC

Results of Modified Ponseti Technique in and a review of literature.

J Clin Orthop Trauma 2020 Mar-Apr;11(2):222-231. Epub 2019 May 7.

Department of Pediatrics, PGIMER & RML Hospital, New Delhi, India.

Introduction: Serial Ponseti casting achieves deformity correction in early presenting idiopathic clubfoot cases normally in around 7 casts. However, there are resistant patients where correction requires more casts than usual. In such patients a modification in standard technique might be required right from the beginning. Read More

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http://dx.doi.org/10.1016/j.jcot.2019.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026550PMC

The 5-Year Outcome of the Ponseti Method in Children With Idiopathic Clubfoot and Arthrogryposis.

J Pediatr Orthop 2020 Feb 6. Epub 2020 Feb 6.

Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE.

Background: The Ponseti method effectively treats idiopathic clubfoot, but its effectiveness in treating the stiffer clubfoot associated with arthrogryposis is less clear. The purpose of this study was to assess the comparative effectiveness of the Ponseti method in 5-year-old children with either idiopathic clubfoot or clubfoot due to arthrogryposis.

Methods: The outcomes of the Ponseti method were retrospectively evaluated in children with idiopathic clubfoot and clubfoot associated with arthrogryposis. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001524DOI Listing
February 2020

Arthrodesis of the Foot or Ankle in Adult Patients with Congenital Clubfoot.

Cureus 2019 Dec 29;11(12):e6505. Epub 2019 Dec 29.

Orthopaedics, Stanford University, Stanford, USA.

Background Although clubfoot that was corrected in childhood rarely recurs in adulthood, persistent deformities or arthritic pain may require further treatment during adulthood. Little evidence exists on the operative procedures utilized in adult clubfoot patients, who were previously treated for congenital clubfoot in childhood, for residual or recurrent deformity or pain. Objective The objective of this study is to characterize the types and frequencies of procedures utilized in adult clubfoot patients, who were previously treated for congenital clubfoot in childhood. Read More

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http://dx.doi.org/10.7759/cureus.6505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988724PMC
December 2019

Effect of inbreeding on the "Club Foot" disorder in Arabian Pureblood horses reared in Italy.

Open Vet J 2019 10 29;9(3):273-280. Epub 2019 Sep 29.

Department of Veterinary Science, University of Pisa, Pisa, Italy.

Background: "The Club Foot" (or "Mismatched Foot") is an acquired or congenital flexural deformity of the distal interphalangeal joint, caused by a shortening of the musculotendinous unit of the deep digital flexor tendon.

Aim: The aim of this research was to detect the incidence of the disorder in Arabian Pureblood horses, attempting to understand its causes and to analyze a possible role of inbreeding in its expression. In this breed, in fact, the pathology is widespread because in the environment of origin, the rocky desert, a hard and almost goat's hoof is not disabling so the selection against this disorder has never been done. Read More

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http://dx.doi.org/10.4314/ovj.v9i3.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794396PMC
October 2019

Integrated bioinformatics analysis of potential pathway biomarkers using abnormal proteins in clubfoot.

PeerJ 2020 20;8:e8422. Epub 2020 Jan 20.

Department of Pediatric Orthopaedics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: As one of the most common major congenital distal skeletal abnormalities, congenital talipes equinovarus (clubfoot) affects approximately one in one thousandth newborns. Although several etiologies of clubfoot have been proposed and several genes have been identified as susceptible genes, previous studies did not further explore signaling pathways and potential upstream and downstream regulatory networks. Therefore, the aim of the present investigation is to explore abnormal pathways and their interactions in clubfoot using integrated bioinformatics analyses. Read More

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http://dx.doi.org/10.7717/peerj.8422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977474PMC
January 2020

Calpainopathy: Description of a Novel Mutation and Clinical Presentation with Early Severe Contractures.

Genes (Basel) 2020 01 25;11(2). Epub 2020 Jan 25.

Grupo de Investigación en Psiquiatría (GIPSI), Departamento de Psiquiatría, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.

Presented here are five members of a family that was ascertained from an isolated, consanguineous, indigenous Amerindian community in Colombia that was affected with calpain 3-related, limb-girdle muscular dystrophy type R1. These patients are homozygous for a unique and novel deletion of four bases (TGCC) in exon 3 of the calpain 3 gene () (NM_000070.2; NP_000061. Read More

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http://dx.doi.org/10.3390/genes11020129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074289PMC
January 2020

Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells.

Stem Cell Res 2020 03 17;43:101712. Epub 2020 Jan 17.

School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Ji'nan, Shandong, China; Shandong Medicinal Biotechnology Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, Shandong, China; Key Laboratory for Biotech-Drugs of National Health Commission, Ji'nan, Shandong, China. Electronic address:

A human induced pluripotent stem cell (iPSC) line (SMBCi002-A) was established from amniocytes (amniotic fluid cells, AFDCs) from a 16-week-old female fetus with clubfoot. Reprogramming and enhancing factors OCT4, SOX2, KLF4, MYC, LIN28 and EBNA1 were delivered using a nonintegrative strategy based on episomal plasmids. Validation assays indicated that this iPSC line has full pluripotency, differentiation potential and genetic stability. Read More

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http://dx.doi.org/10.1016/j.scr.2020.101712DOI Listing

Radiological study of anatomical bony arrangement of the clubfoot deformity and its correlation with the Pirani clinical scoring system: A multicenter study.

Sudan J Paediatr 2019 ;19(2):101-109

Department of Paediatrics and Child Health, Faculty of Medicine University of Gezira, Wad Medani, Sudan.

Club foot or congenital talipes equinovarus (CTEV) is a common developmental disorder of the foot, affecting 1 per 1,000 live births. The main goal of this study is to evaluate the anatomical bony arrangement of the clubfoot deformity radiologically and to correlate this arrangement with the Pirani clinical scoring system. This descriptive, analytical study was conducted in three centres in Sudan. Read More

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http://dx.doi.org/10.24911/SJP.106-1573461977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962271PMC
January 2019