4,696 results match your criteria Clubfoot


The Predictive Value of Radiographs and the Pirani Score for Later Additional Surgery in Ponseti-Treated Idiopathic Clubfeet, an Observational Cohort Study.

Children (Basel) 2022 Jun 10;9(6). Epub 2022 Jun 10.

Erasmus MC, Sophia Children's Hospital, 3015 CN Rotterdam, The Netherlands.

There are few validated predictors of the need for additional surgery in idiopathic clubfeet treated according to the Ponseti method. Our aim was to examine if physical examination (Pirani score) and radiographs at the age of three months (after initial correction of the clubfeet) can predict the future need for additional surgery. In this retrospective cohort study, radiographs of idiopathic clubfeet were made at the age of three months. Read More

View Article and Full-Text PDF

Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.

Cell Mol Life Sci 2022 Jun 21;79(7):375. Epub 2022 Jun 21.

Department of Genetics and Endocrinology, Guangzhou Women and Children's Medical Center, the Affiliated Hospital of Guangzhou Medical University, 9 Jinsui Road, Guangzhou, China.

The SLC25A32 dysfunction is associated with neural tube defects (NTDs) and exercise intolerance, but very little is known about disease-specific mechanisms due to a paucity of animal models. Here, we generated homozygous (Slc25a32 and Slc25a32) and compound heterozygous (Slc25a32) knock-in mice by mimicking the missense mutations identified from our patient. A homozygous knock-out (Slc25a32) mouse was also generated. Read More

View Article and Full-Text PDF

The impact of socio-economic factors on parental non-adherence to the Ponseti protocol for clubfoot treatment in low- and middle-income countries: A scoping review.

EClinicalMedicine 2022 Jun 12;48:101448. Epub 2022 May 12.

The Program in Global Surgery and Social Change, Harvard Medical School, 641 Huntington Ave, Boston, MA 02115, United States.

Background: The Ponseti treatment is considered the gold standard for clubfoot globally, but requires strong engagement from parents. The aim of this review is to assess the impact of socio-economic factors on the presence of drop-out, relapse or non-compliance during Ponseti treatment in low and middle-income countries (LMICs).

Methods: This scoping review includes all articles available from inception until 4. Read More

View Article and Full-Text PDF

Clubfoot and its implications for the locomotion of a medieval skeleton from Estremoz, Portugal.

Int J Paleopathol 2022 Jun 11;38:13-17. Epub 2022 Jun 11.

Biology Department, University of Évora, Portugal; Research Centre for Anthropology and Health, University of Coimbra, Portugal.

Objective: This study describes foot bone anomalies and the degenerative changes associated with locomotion adaptations.

Materials: An adult male (approximately 29-46 years old) from Estremoz, Portugal (13th-15th century).

Methods: The skeletal anomalies observed in this skeleton were described and measurements were compared between both sides of the individual and with the mean of the adult males from the same collection. Read More

View Article and Full-Text PDF

Disability and Quality of Life After Talectomy for Arthrogryposis Multiplex Congenita.

Foot Ankle Int 2022 Jun 14:10711007221104076. Epub 2022 Jun 14.

Department of Orthopedics, Health Science University Baltalimani Bone Diseases Education and Research Hospital, Istanbul, Turkey.

Background: Arthrogryposis multiplex congenita (AMC) is one of the causes of rigid and resistant clubfoot. Talectomy is considered as a primary or salvage procedure for recurrent equinovarus deformity in these patients. We conducted this study to assess patients with AMC who underwent talectomy for the correction of foot and ankle deformities in terms of health-related quality of life and disability. Read More

View Article and Full-Text PDF

Kinematic differences in the presentation of recurrent congenital talipes equinovarus (clubfoot).

Gait Posture 2022 May 27;96:195-202. Epub 2022 May 27.

Griffith Centre of Biomedical and Rehabilitation Engineering (GCORE), Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD 4222, Australia; Queensland Children's Motion Analysis Service, Department of Orthopaedic Surgery Queensland Children's Hospital, Brisbane, QLD 4101, Australia; Research Development Unit, Caboolture and Kilcoy Hospitals, Metro North Health, Caboolture, QLD 4510, Australia.

Background: The tibialis anterior tendon transfer (TATT) is the suggested surgical intervention in the Ponseti method for treatment of dynamic recurrent congenital talipes equinovarus (clubfoot) presenting as hindfoot varus and forefoot supination during the swing phase of gait. The indication for surgery, however, is typically based on visual assessment, which does not sufficiently examine the variability of foot motion in this cohort.

Research Question: The aim of this research was to determine whether subgroups, based on foot model kinematics, existed within a clubfoot cohort being considered for TATT surgery. Read More

View Article and Full-Text PDF

Surgical Management of the Undercorrected and Overcorrected Severe Club Foot Deformity.

Foot Ankle Clin 2022 Jun 11;27(2):491-512. Epub 2022 May 11.

Department of Orthopaedic Surgery, University of Colorado School of Medicine; Steps2Walk.

Managing complications of clubfoot deformities can be very challenging. Some patients present with recurrent clubfoot and residual symptoms, and some present with overcorrection leading to a severe complex flatfoot deformity. Both can lead to long-term degenerative changes of the foot and ankle joints owing to deformity caused by unbalanced loading. Read More

View Article and Full-Text PDF

Attaining a British consensus on managing idiopathic congenital talipes equinovarus up to walking age.

Bone Joint J 2022 Jun;104-B(6):758-764

Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Aims: The aim of this study was to gain an agreement on the management of idiopathic congenital talipes equinovarus (CTEV) up to walking age in order to provide a benchmark for practitioners and guide consistent, high-quality care for children with CTEV.

Methods: The consensus process followed an established Delphi approach with a predetermined degree of agreement. The process included the following steps: establishing a steering group; steering group meetings, generating statements, and checking them against the literature; a two-round Delphi survey; and final consensus meeting. Read More

View Article and Full-Text PDF

The demographics of talipes equinovarus in Indiana, with a particular emphasis on comparisons between clubfoot types.

J Pediatr Orthop B 2022 May 30. Epub 2022 May 30.

Orthopedic Surgery, Riley Children's Hospital, Indianapolis, Indiana.

Talipes equinovarus (TEV) can be an isolated idiopathic deformity or associated with various syndromes. The purpose of our study was to examine the demographics of TEV in Indiana. All TEV patients from 2010 to 2019 from our institution were reviewed, recording standard demographic variables. Read More

View Article and Full-Text PDF

Anatomical Structures Responsible for CTEV Relapse after Ponseti Treatment.

Children (Basel) 2022 Apr 19;9(5). Epub 2022 Apr 19.

Medical Department, Aristotelion University of Thessaloniki, 54124 Thessaloniki, Greece.

Relapse of deformity after a successful Ponseti treatment remains a problem for the management of clubfoot. An untreated varus heel position and restricted dorsal flexion of the ankle are the main features of recurrences. We analyze the anatomical structures responsible for these recurrences. Read More

View Article and Full-Text PDF

The foot drawing method: reliability of measuring foot length and outward rotation in children with clubfoot.

BMC Musculoskelet Disord 2022 May 28;23(1):506. Epub 2022 May 28.

Department of Clinical Sciences Lund, Orthopedics, Lund University, Skane University Hospital, 221 85, Lund, Sweden.

Background: The Ponseti method is the gold standard for clubfoot treatment. However, relapse and residual gait deviations are common, and follow-up until 7 years of age is recommended. We evaluated the reliability of the foot drawing method, a new instrument for the follow-up of clubfoot. Read More

View Article and Full-Text PDF

Initiating Ponseti management in preterm infants with clubfoot at term age.

J Child Orthop 2022 Apr 30;16(2):141-146. Epub 2022 Apr 30.

Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Macquarie Park, NSW, Australia.

Purpose: Currently, the optimal time to initiate treatment among preterm infants with clubfoot is unknown. The aim of this study was to describe treatment outcomes up to 1 year post-correction following Ponseti management in infants who were born preterm but treated at term age.

Methods: A retrospective chart audit was conducted at a major pediatric hospital on preterm infants with clubfoot who commenced Ponseti management at term age (≥37 weeks of gestation). Read More

View Article and Full-Text PDF

Are early antero-posterior and lateral radiographs predictive of clubfoot relapse requiring surgical intervention in children treated by Ponseti method?

J Child Orthop 2022 Feb 5;16(1):35-45. Epub 2022 Apr 5.

Department of Paediatric Orthopaedics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.

Purpose: To investigate the value of antero-posterior and lateral radiographs in predicting clubfoot relapse after treatment with the Ponseti method.

Methods: This was a retrospective review of 104 children (157 feet) younger than 3 months of age with idiopathic clubfoot treated using the Ponseti method at our institution between January 2007 and December 2014. All patients underwent Achilles tenotomy and were divided into two groups according to the need for further surgery to correct the deformity: relapsed group (24 patients; 36 feet) and non-relapsed group (80 patients; 121 feet). Read More

View Article and Full-Text PDF
February 2022

Ultrasound measurements in clubfoot treated with the Ponseti method and risk factors for recurrence: A retrospective study.

J Child Orthop 2022 Feb 5;16(1):46-54. Epub 2022 Apr 5.

University of Montreal, Montreal, QC, Canada.

Background: Recurrence remains the main challenge in the treatment of clubfoot. The primary goal of this study is to determine if ultrasound measurements are associated with recurrence after successful management with the Ponseti method. Furthermore, other factors are identified which can be associated with recurrence of the deformity. Read More

View Article and Full-Text PDF
February 2022

Talipes Equinovarus in Loeys-Dietz Syndrome.

J Pediatr Orthop 2022 May 25. Epub 2022 May 25.

Departments of Orthopaedic Surgery.

Background: Loeys-Dietz syndrome (LDS) commonly presents with foot deformities, such as talipes equinovarus (TEV), also known as "clubfoot." Although much is known about the treatment of idiopathic TEV, very little is known about the treatment of TEV in LDS. Here, we summarize the clinical characteristics of patients with LDS and TEV and compare clinical and patient-reported outcomes of operative versus nonoperative treatment. Read More

View Article and Full-Text PDF

Establishment of a control induced pluripotent stem cell line SMBCi018-A from a patient with congenital talipes equinovarus.

Stem Cell Res 2022 Jul 17;62:102814. Epub 2022 May 17.

Department of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University, Ji'nan 250014, Shandong, China; Biomedical Sciences College, Shandong Medicinal Biotechnology Centre, Shandong First Medical University& Shandong Academy of Medical Sciences, Ji'nan 250062, Shandong, China; Key Lab for Biotech-Drugs of National Health Commission, Ji'nan 250062, Shandong, China; Key Lab for Rare & Uncommon Diseases of Shandong Province, Ji'nan 250062, Shandong, China. Electronic address:

Congenital talipes equinovarus (CTEV) is a congenital malformation affecting approximately 1/700-1/1000 of live borns. To date extensive epidemiological and biological studies have been operated to solve this issue, the most meaningful findings in clubfoot genetics involve PITX1 variants, which were associated with clubfoot phenotype in mice and humans. According to recent studies, the PITX1-TBX4 transcriptional pathway regulatory for early limb development has identified a key developmental pathway in clubfoot etiology by the common disease-rare hypothesis. Read More

View Article and Full-Text PDF

Correction of a Complex Foot Deformity With V and Y Osteotomy and Ilizarov Method.

J Foot Ankle Surg 2022 Feb 15. Epub 2022 Feb 15.

Orthopaedic Clinic, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.

Many authors consider the Ilizarov method as the best choice for correction of complex multiplanar foot deformities. Fifty-one patients, for a total of 55 feet, underwent V or Y osteotomy (respectively 32 and 23), 12 were due to congenital clubfoot outcomes, 11 were from post-traumatic pathologies, 9 from hemimelia, 7 from Charcot-Marie-Tooth, 5 from poliomyelitis, 3 from spina bifida, 2 from myopathy, 2 from poly-epiphyseal dysplasia, 1 from achondroplasia, 1 from arthrogryposis, 1 patient from Charcot's foot and 1 rheumatoid arthritis. All patients were contacted to undergo AOFAS and EQ-5D-5L questionnaire. Read More

View Article and Full-Text PDF
February 2022

Incidence of Congenital Clubfoot: Preliminary Data from Italian CeDAP Registry.

Int J Environ Res Public Health 2022 04 29;19(9). Epub 2022 Apr 29.

Unit of Orthopaedics and Traumatology, University of Trieste, Strada di Fiume, 34149 Trieste, Italy.

(1) Background: We find the incidence of clubfoot in Italy from "Certificate of Delivery Care Registry (CeDAP)", a database of the Italian Ministry of Health, the most comprehensive public data available for this purpose. (2) Methods: The CeDAP registry is a web system that provides epidemiological and sociodemographic information about newborns. It started on 1 January 2002, following the ministerial Decree no. Read More

View Article and Full-Text PDF

Clinically Detected Leg Length Discrepancy in Patients With Idiopathic Clubfoot Deformity: Prevalence and Outcomes.

J Pediatr Orthop 2022 May 10. Epub 2022 May 10.

The Hospital for Sick Children, Toronto, ON, Canada.

Background: This study evaluates the prevalence and outcomes of patients with idiopathic clubfoot and clinically detected limb length discrepancy (LLD).

Methods: This is a retrospective cohort study of idiopathic clubfoot patients in a Research Ethics Board-approved clubfoot registry. Patients with LLD ≥0. Read More

View Article and Full-Text PDF

Achilles tendon surgery in clubfoot: Are long term sequelae predictable?

Pediatr Med Chir 2022 May 3;44(1). Epub 2022 May 3.

Pediatric Orthopedic and Traumatology Unit, Children's Hospital, AON SS Antonio e Biagio e Cesare Arrigo, Alessandria.

Congenital Clubfoot (CCF) treatment involves a surgical procedure on the Achilles tendon most of the time, i.e. tenotomy or, in selected cases, Z-plasty lengthening. Read More

View Article and Full-Text PDF

Eight-year Review of a Clubfoot Treatment Program in Pakistan With Assessment of Outcomes Using the Ponseti Technique: A Retrospective Study of 988 Patients (1,458 Clubfeet) Aged 0 to 5 Years at Enrollment.

J Am Acad Orthop Surg Glob Res Rev 2022 04 1;6(4). Epub 2022 Apr 1.

From the Indus Hospital and Health Network, Karachi, Pakistan (Ahmed and Moosa); Interactive Research and Development, Karachi, Pakistan (Muhammad, Iftikhar, and Samad); the Department of Orthopaedics (Khan and Chinoy), and the Department of Paediatric Surgery, The Indus Hospital, Karachi, Pakistan (Samad).

Objective: To conduct an 8-year retrospective review of a clubfoot treatment program using the Ponseti technique with close monitoring of outcomes.

Methods: Between October 2011 and August 2019, 988 children with 1,458 idiopathic clubfeet were enrolled, ages ranging from new born up to 5 years. Ponseti treatment was used, and progress was monitored by comparing mean Pirani scores at enrollment (P1), initiation of bracing (P2), and end of treatment (P3) or most recent visit (P4) for children under treatment. Read More

View Article and Full-Text PDF

Idiopathic Congenital Talipes Equinovarus in Wisconsin Newborns: Incidence and Associated Risk Factors.

WMJ 2022 Apr;121(1):36-40

Department of Orthopaedic Surgery, Children's Wisconsin, Milwaukee, Wisconsin.

Introduction: Clubfoot, also known as idiopathic congenital talipes equinovarus, is one of the most common pediatric deformities affecting 1 to 2 in every 1,000 live births. We sought to provide the first known analysis of incidence of clubfoot diagnoses in the most populous region of Wisconsin as well as risk factors associated with the deformity.

Methods: We conducted a retrospective study on children treated for clubfoot at Children's Wisconsin from January 1, 2004, through December 31, 2018. Read More

View Article and Full-Text PDF

Subtalar dislocation: a narrative review.

Musculoskelet Surg 2022 Apr 18. Epub 2022 Apr 18.

Department of Orthopaedics and Traumatology, Rovereto Hospital, Rovereto, Italy.

Background: Subtalar joint dislocation (1% of all dislocations) is the permanent loss of articular relationships in the talonavicular and talocalcaneal joints, without other involvement of the foot. Dislocation can occur medially (85%), laterally (15%), posteriorly (2.5%) and anteriorly (1%). Read More

View Article and Full-Text PDF

Romanian patients' access to clubfoot treatment services.

J Med Life 2022 Feb;15(2):278-283

Department of Public Health, Faculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, Cluj-Napoca, Romania.

The number of clubfoot new cases in Romania is on the rise. According to orthopedic research, the Ponseti method is the elective treatment for clubfeet. This paper aims to provide an overview of the current facilitators and barriers in accessing clubfoot treatment services in Romania and to assess the impact of care-related factors on patients' well-being. Read More

View Article and Full-Text PDF
February 2022

Measuring Foot Abduction Brace Wear Time Using a Single 3-Axis Accelerometer.

Sensors (Basel) 2022 Mar 22;22(7). Epub 2022 Mar 22.

Shaare Zedek Medical Center, Jerusalem 9103102, Israel.

The recommended treatment for idiopathic congenital clubfoot deformity involves a series of weekly castings, surgery, and a period of bracing using a foot abduction brace (FAB). Depending on the age of the child, the orthotic should be worn for periods that reduce in duration as the child develops. Compliance is vital to achieve optimal functional outcomes and reduce the likelihood of reoccurrence, deformity, or the need for future surgery. Read More

View Article and Full-Text PDF

What is New in Pediatric Orthopaedic Foot and Ankle.

J Pediatr Orthop 2022 May-Jun 01;42(5):e448-e452

Department of Orthopaedic Surgery, Stanford University, Redwood City, CA.

Background: This paper aims to report on the last 5 years of relevant research on pediatric foot and ankle pathology with specific focus on clubfoot, congenital vertical talus, toe walking, tarsal coalitions, pes planovalgus with or without accessory navicular, foot and ankle trauma, and talar dome osteochondritis dessicans.

Methods: The Browzine platform was used to review the table of contents for all papers published in the following target journals related to the treatment of pediatric foot and ankle conditions. Search results were further refined to include clinical trials and randomized controlled trials published from March 1, 2015 to November 15, 2021. Read More

View Article and Full-Text PDF

Staged Correction of Severe Recurrent Clubfoot Deformity With Dislocation of the Chopart Joint Using a Hexapod External Fixator and Unconventional Arthrodesis.

J Am Acad Orthop Surg Glob Res Rev 2022 04 7;6(4). Epub 2022 Apr 7.

From the Department of Orthopaedic Surgery, Henry Ford Hospital, Detroit, MI.

Despite success of the Ponseti method, a subset of patients with clubfeet experience residual deformity. Surgical release after unsuccessful serial casting can lead to residual clubfoot deformities, including a flat-top talus. We present a case of a 17-year-old boy with a dysmorphic ankle and a complete dorsal dislocation of the Chopart joint. Read More

View Article and Full-Text PDF

Tibialis Anterior and Posterior Tendon Transfer for Clubfoot Relapse in a Child with Duchenne Muscular Dystrophy: A Case Report.

JBJS Case Connect 2022 04 6;12(2). Epub 2022 Apr 6.

Department of Orthopaedic Surgery, Stanford University School of Medicine, Palo Alto, California.

Case: A boy with bilateral congenital clubfoot, Kleefstra syndrome, and Duchenne muscular dystrophy (DMD) developed clubfoot relapse after excellent initial correction with the Ponseti method and maintenance abduction bracing. A traditional clubfoot tibialis anterior transfer was augmented with a tibialis posterior tendon transfer, given underlying DMD at ages 7 and 10 years for the right foot and left foot, respectively.

Conclusion: This case illustrates successful maintenance of correction using combined tibialis anterior and tibialis posterior tendon transfer. Read More

View Article and Full-Text PDF

Semirigid Fiberglass Casting for the Early Management of Clubfoot: A Single-Center Experience.

Cureus 2022 Feb 28;14(2):e22683. Epub 2022 Feb 28.

Orthopaedics, Pediatric Specialists of Virginia, Fairfax, USA.

Background Semirigid fiberglass (SRF) is an alternative material to plaster of Paris (POP) for idiopathic clubfoot casting in the Ponseti method. The purpose of this study was to evaluate early clinical outcomes in a series of idiopathic clubfoot patients treated with SRF at a single institution and to compare these findings to historical norms with POP casting present in the literature. Methods A series of idiopathic clubfoot patients managed exclusively with SRF in the Ponseti method was identified. Read More

View Article and Full-Text PDF
February 2022

Factors predictive of Ponseti casting for treating clubfoot: analysis of Bayesian Poisson regression model.

Eur Rev Med Pharmacol Sci 2022 03;26(6):1868-1875

Department of Public Health, North South University, Dhaka, Bangladesh.

Objective: Clubfoot is a growing public health concern in Bangladesh, with the incidence of approximately 0.64 to 6.8 in every 1000 live births. Read More

View Article and Full-Text PDF