Search Our Scientific Publications & Authors

Wounds 2021 Mar;33(3):E24-E27

Division of Pressure Ulcer Prevention, Graduate School of Medical Sciences, Kyushu University, Japan.

Introduction: Reports of retroperitoneal infection related to a sacral pressure injury (PI) are rare, and none of the reports described the direct spread of infection through the sacrum to the retroperitoneum. The authors present, to their knowledge, the first report of a severely infected PI that showed full-thickness sacral destruction and direct retroperitoneal penetration.

Case Report: A 63-year-old female was referred for management of a stage 4 sacral PI complicated by a retroperitoneal abscess. Read More

Wounds 2021 Feb;33(2):E20-E23

Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, Minnesota.

Introduction: Delayed wound healing and ulceration in radiated tissue is a surgical challenge. Autologous fat grafting can reverse skin changes secondary to radiation such as fibrosis, scarring, contracture, and pain. Adipose-derived stem cells are thought to contribute to the regenerative properties of fat. Read More

Ann Plast Surg 2021 Apr 21. Epub 2021 Apr 21.

From the Department of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

Background: Complication rates after spinal surgery are high, in part because of surgical advancements that have made procedures available to a broader range of medically complicated patients. The high rates of infection, hematoma, and dehiscence resulting in open wounds after spinal surgery often warrant plastic surgery involvement. In this study, we aim to examine the effects of preoperative and operative risk factors on complication rates, reoperation rates, and hospital length of stay after flap reconstruction of spinal defects. Read More

Int J Low Extrem Wounds 2021 Apr 15:15347346211004305. Epub 2021 Apr 15.

University Hospital Brno, Masaryk University, Jihomoravský, Czech Republic.

Necrotizing fasciitis is a life-threatening skin and soft tissue infection associated with high morbidity and mortality in adult patients. This infection can present as either type 1 infection caused by a mixed microflora (, , sp., and sp. Read More

J Craniofac Surg 2021 Apr 5. Epub 2021 Apr 5.

Plastic Surgery and Burns Unit, Schneider Children's Medical Center of Israel Department of Plastic Surgery and Burns, Rabin Medical Center, affiliated with the Sackler Faculty of Medicine, Petah Tikva, Israel.

Abstract: Pediatric scalp defects may be challenging, due to their variant tension level and specific etiologies. Tissue characteristics and pre- and post-management considerations may pose difficulties to reconstruction in the pediatric patient. Primary closure is the preferred surgical technique but is not always possible. Read More

Medicine (Baltimore) 2021 Feb;100(7):e24791

Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University.

Rationale: Despite significant advances in surgical techniques and implants, the clinical outcome of high-energy pilon fractures remains unsatisfactory, which continues to represent numerous challenges for orthopedic trauma surgeons.

Patient Concerns: A 62-year-old man injured his right ankle after falling from a 3 m high place. There were no open wounds or other complications. Read More

J Surg Case Rep 2021 Jan 18;2021(1):rjaa562. Epub 2021 Jan 18.

Lewis Gale Medical Center, Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA.

This case of bowel obstruction with multiple postoperative complications provides unique insight into the challenges faced by providers caring for intellectually disabled patients with acute surgical abdominal pathology and poor compliance. In this case, the component separation was utilized as a method of facilitated wound closure and compliance in a postoperative course highlighted by both dehiscence and wound infection. The patient, only able to communicate the presence of abdominal pain due to his disability, was surgically managed for a bowel obstruction secondary to a cecal volvulus. Read More

BMJ Case Rep 2021 Jan 25;14(1). Epub 2021 Jan 25.

Academic Department of Trauma & Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK

A 35-year-old woman attended the emergency department after sustaining a reverse oblique proximal femur fracture, which was amenable to intramedullary nailing. Her presentation was complicated by a background of severe generalised recessive dystrophic epidermolysis bullosa, with extensive blistering of most of her skin, including the area over the standard surgical incision sites. For the successful management of this case, extensive input from the multidisciplinary team was required, with the team facing several challenges. Read More

Wounds 2020 Dec;32(12):E71-E75

Department of Orthopaedic Surgery, University Medical Center Maribor, Maribor, Slovenia.

Introduction: The advantages of using negative pressure wound therapy with instillation and dwell time (NPWTi-d) of a topical solution that dwells on the wound have been shown to include removal of fibrinous and bacterial exudate and increased granulation tissue formation. The treatment is best suited for chronic, complex wounds with areas of nonviable tissue on the wound surface.

Case Report: A 73-year-old female with spondylolisthesis and stenosis of the spinal canal experienced dehiscence formation of the postoperative wound with continuous exudate after fusion and decompression surgery (TLIF L4-L5) of the lumbar spine. Read More

Nano Today 2021 Feb 20;36. Epub 2020 Dec 20.

Division of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Cambridge, MA 02139, USA.

Sutures, staples, clips and skin closure strips are used as the gold standard to close wounds after an injury. In spite of being the present standard of care, the utilization of these conventional methods is precarious amid complicated and sensitive surgeries such as vascular anastomosis, ocular surgeries, nerve repair, or due to the high-risk components included. Tissue adhesives function as an interface to connect the surfaces of wound edges and prevent them from separation. Read More

Am Surg 2020 Dec 18:3134820923297. Epub 2020 Dec 18.

92602 Department of Surgery, Maine Medical Center, Portland, ME, USA.

Background: The combination of traumatic simultaneous diaphragmatic rupture and chest wall herniation remains rare, with 42 cases of traumatic transdiaphragmatic intercostal hernia (TDIH) reported in the literature since 1946. An accurate count of cases is difficult to obtain, as TDIH nomenclature has been variable. Risk factors for traumatic TDIH are not well established. Read More

Prim Health Care Res Dev 2020 12 16;21:e63. Epub 2020 Dec 16.

Nursing Services, National Healthcare Group Polyclinics, Singapore.

Aim: To explore the experiences of patients living with diabetic lower extremity amputation (DLEA) and its post-amputation wound in primary care.

Background: DLEA, including both minor and major amputation, is a life-altering condition that brings numerous challenges to an individual's life. Post-amputation physical wound healing is complicated and challenging because of wound dehiscence and prolonged healing times. Read More

Am J Case Rep 2020 Dec 5;21:e927461. Epub 2020 Dec 5.

Department of Surgery, Azevedo Lima State General Hospital, Niterói, RJ, Brazil.

BACKGROUND Duodenal trauma usually consists of retroperitoneal lesions. Its management can be complicated by the location of the injury and difficulty in making an early diagnosis. Duodenal injuries are divided into blunt and penetrating trauma, and the possible results are hematoma, laceration, and devascularization. Read More

Minerva Med 2020 Dec 2. Epub 2020 Dec 2.

Stem Cell Institute, University of Science, Ho Chi Minh City, Viet Nam.

Wound healing, especially of chronic wounds, is still an unmet therapeutic area since assessment and management are extremely complicated. Although many efforts have been made to treat wounds, all strategies have achieved limited results for chronic wounds. Stem cell-based therapy is considered a promising approach for complex wounds such as those occurring in diabetics. Read More

Int Orthop 2021 01 16;45(1):233-240. Epub 2020 Nov 16.

Tanta University, Tanta, Egypt.

Purpose: Complex ankle fractures accompanied with infection and segmental bone loss are a worrying issue. This prospective study was conducted to explore the effectiveness of using Ilizarov concepts in achieving salvage arthrodesis and reconstructing post-debridement defects in such complicated scenarios.

Methods: A total of 44 consecutive patients (mean age 35. Read More

World J Surg Oncol 2020 Nov 14;18(1):301. Epub 2020 Nov 14.

General Surgery III, ASST Papa Giovanni XXIII, Bergamo, Italy.

Background: Treatment of esophageal perforations and postoperative anastomotic leaks of the upper gastrointestinal tract remains a challenge. Endoluminal vacuum-assisted closure (E-Vac) therapy has positively contributed, in recent years, to the management of upper gastrointestinal tract perforations by using the same principle of vacuum-assisted closure therapy of external wounds. The aim is to provide continuous wound drainage and to promote tissue granulation, decreasing the needed time to heal with a high rate of leakage closure. Read More

J Med Case Rep 2020 Nov 14;14(1):221. Epub 2020 Nov 14.

Department of Thoracic Surgery, National Hospital Organization Himeji Medical Center, Himeji, Japan.

Background: Intraoperative contralateral pneumothorax during one-lung ventilation is a rare but life-threatening complication. Although the exact incidence is unknown, only 14 cases with this complication have been reported until now.

Case Presentation: A 67-year-old Japanese man with a weight of 80 kg, height of 162. Read More

Nagoya J Med Sci 2020 Aug;82(3):487-498

Department of Biomedical Sciences, College of Life and Health Science, Chubu University, Kasugai, Japan.

Impaired wound healing is one of the most common complications of diabetes, and is known to be caused by multiple complicated factors. For instance, impaired angiogenesis, neuropathy, and hyperglycemia all function to delay subsequent wound closure. Alternatively, moist wound healing, which provides an appropriate environment for wounds, was reported to permit rapid healing by managing wound exudate. Read More

Int J Low Extrem Wounds 2020 Oct 30:1534734620968378. Epub 2020 Oct 30.

Columbia University Medical Center, New York, NY, USA.

Diabetes mellitus affects hundreds of millions of people worldwide, each of which have up to a 25% risk of developing a diabetic foot ulcer (DFU) during their lifetime. With poor DFU healing rates using standard of care, advanced treatments are introduced to attempt to close the wound. The objective of this preliminary clinical evaluation was to evaluate lower extremity ulcers treated with a novel bioengineered wound product (BWP). Read More

Antibiotics (Basel) 2020 Aug 19;9(9). Epub 2020 Aug 19.

Triticum Exploitatie BV, 6222NK Maastricht, The Netherlands.

Diabetic ulcers are at risk of becoming chronic and infected, as diabetics have hampered vascular structures, limiting oxygen and nutrient supply. These wounds can lead to pain, malodor, functional problems, and amputation. The current rise in antibiotic resistance demands for complementary therapies. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Aug;23(8):745-751

Department of Colorectal Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, Guangzhou, Guangdong 510655, China.

To preliminarily evaluate the feasibility and safety of laparoscopic Parks procedure for chronic radiation proctopathy (CRP). A descriptive cohort study was carried out. The clinical and follow-up data of 19 patients who received laparoscopic Parks procedure due to CRP in the Sixth Affiliated Hospital of Sun Yat-sen University from July 2013 to March 2019 were retrospectively analyzed. Read More

J Wound Care 2020 Aug;29(Sup8):S12-S17

Village Podiatry Centers, Smyrna, GA, US.

Objective: The objective of this study was to assess the clinical effectiveness of surgically implanted cryopreserved human umbilical cord allograft in treating hard-to-heal wounds with and without osteomyelitis.

Method: In this single-centre, retrospective investigation, wounds (average size 6.9±10. Read More

J Pediatr Intensive Care 2020 Sep 13;9(3):218-221. Epub 2020 Jan 13.

Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Foreign body-related injuries to aerodigestive tract and large neck vessels are rare but can be catastrophic if not identified and treated in time. We report an infant with impacted foreign body (pen cap) in the pharynx which went unnoticed until it led to the formation of a fistula with the internal jugular vein (IJV) and massive hemorrhage. His course was complicated by ventilator-associated pneumonia, air leaks, shock, acute kidney injury, prolonged mechanical ventilation, and pharyngocutaneous fistula. Read More

J Wound Care 2020 Jul;29(Sup7):S6-S15

Ofstead & Associates, Inc., 1360 Energy Park Drive, Suite 300, St. Paul, MN 55102.

Background: Wound infections result in considerable morbidity, mortality and healthcare costs. Antibiotic resistance has complicated wound healing, and new, non-antibiotic-based treatment methods are being developed.

Aims: To evaluate evidence on the safety, efficacy and real-world effectiveness of electroceutical devices (ECDs) that provide continuous electrical stimulation to wounds. Read More

Wound Manag Prev 2020 07;66(7):33-38

Division of Plastic Surgery, University of Mississippi Medical Center, Jackson, Mississippi.

Os styloideum is an accessory wrist bone at the base of the second and third metacarpals. Similar to metacarpal bossing, chronic pain secondary to the development of osteoarthritis and tendon irritation is common. Conservative management consists of splinting and steroid injections, with surgical resection being the definitive treatment. Read More

Angiol Sosud Khir 2020 ;26(2):175-182

Department of Vascular Surgery, Municipal Multimodality Hospital #2, Saint Petersburg, Russia.

Described herein is a clinical case report regarding a patient presenting with traumatic rupture of the aortic isthmus with the development of a pseudoaneurysm occupying virtually the entire posterior mediastinum and measuring 20?10 cm in size. He was immediately treated as an emergency to undergo prosthetic reconstruction of the portion of the aortic arch and descending thoracic aorta by means of temporary bypass grafting with a synthetic graft in order to protect the visceral organs. The postoperative period was complicated by oesophageal perforation with the formation of an oesophago-paraprosthetic fistula, infection of the vascular graft, accompanied by the development of pleural empyema and mediastinitis. Read More

Zhonghua Shao Shang Za Zhi 2020 Jun;36(6):451-457

Department of Gynecologic Oncology, Hunan Cancer Hospital, Changsha 410008, China.

To explore the selection and effects of flap/myocutaneous flap repair methods for the defect after perineum tumor resection. From January 2011 to February 2017, 31 patients with vulvar tumor who were admitted to Hunan Cancer Hospital underwent repair of wound after tumor resection with various flaps/myocutaneous flaps. The patients were composed of 5 males and 26 females, aged 39-76 years, with 27 vulvar cancer and 4 Paget's disease in primary diseases. Read More

Transplant Proc 2020 Nov 21;52(9):2839-2843. Epub 2020 Jun 21.

Division of Transplant Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address:

Background: Intestinal transplantation (ITx) is performed as an isolated ITx or as a part of multivisceral transplantation for intestinal failure secondary to short gut syndrome, inflammatory bowel disease, trauma, and sequelae of chronic parenteral nutrition dependence. Wound complications after ITx are very common, and abdominal wound closure cannot be immediately achieved in half of cases.

Case Presentation: A 25-year-old man sustained an abdominal crush injury causing complete loss of his small intestine, requiring an isolated ITx in March 2016. Read More

Int Orthop 2020 07 30;44(7):1341-1352. Epub 2020 May 30.

Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, 10 C. Heymanslaan, Entrance 75, Route 740, 9000, Ghent, East Flanders, Belgium.

Purpose: Adequate exposure in revision of total shoulder arthroplasty (TSA) is important for optimal prosthesis placement and functional results. A clavicular osteotomy in difficult cases of revision TSA is a useful surgical technique that increases the superior exposure area, provides safer dissection, minimizes damage to the anterior deltoid muscle, improves glenoid access, and allows for superior dislocation of the humeral component. There is a paucity of literature analyzing the clavicular osteotomy during challenging cases of revision TSA. Read More

J Adhes Dent 2020 ;22(3):249-254

Purpose: The management of complicated crown-root fractures is challenging for endodontic restoration. The present case describes a patient who sustained trauma to the maxillary right central incisor.

Materials And Methods: Clinical and radiographic examination showed a complicated crown-root fracture and incomplete root development with periapical radiolucency and inadequate endodontic treatment with overfilling. Read More