123,921 results match your criteria Clinics in Podiatric Medicine and Surgery [Journal]


Regression of human immunodeficiency virus-associated oral Kaposi sarcoma with combined antiretroviral therapy: A case report and literature review.

Head Neck 2018 Dec 15. Epub 2018 Dec 15.

Oral Pathology, Department of Stomatology, University of Sao Paulo School of Dentistry, Sao Paulo, Brazil.

Background: Kaposi's sarcoma (KS) is the most prevalent malignant neoplasia in human immunodeficiency virus positive (HIV+) patients for which the primary mode of management was chemotherapy.

Methods: We have presented the case of a newly diagnosed HIV+ male patient who was diagnosed with a pedunculated nodule in the anterior region of the hard palate, measuring 3.5 cm in diameter and with 2 months of evolution. Read More

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December 2018

Non-adherence to psychotropic medication assessed by plasma levels in newly admitted psychiatric patients.

Psychiatry Clin Neurosci 2018 Dec 15. Epub 2018 Dec 15.

Medical University Innsbruck, Department of Psychiatry, Psychotherapy and Psychosomatics, Division of experimental Psychiatry and Psychotherapy, Austria.

Aims: Non-adherence or partial adherence to psychotropic medication is found in 18-70% of patients. However, many previously used methods for the assessment of adherence (e.g. Read More

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December 2018

The Impact of the Patient-Centered Medical Home on Asthma-Related Visits to the Emergency Room: A Fixed Effects Regression Approach.

Matern Child Health J 2018 Dec 14. Epub 2018 Dec 14.

Department of Health Policy and Administration, Pennsylvania State University, 601A Donald H. Ford Building, University Park, PA, 16802, USA.

Objective To estimate the effect of a patient-centered medical home (PCMH) intervention on asthma-related emergency room (ER) visits of pediatric patients. Methods Patients receiving care at pediatric primary care practices participating in the Florida Pediatric Medical Home Demonstration Project as well as pediatric patients treated at non-participating clinics were identified from 4 years of claims and enrollment data. We estimate several fixed effects logistic regression models using one pre-treatment year and three post-treatment years to investigate whether asthma-related ER visits decreased because of the PCMH intervention. Read More

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December 2018

Strongyloides stercoralis infection in imported and local dogs in Switzerland: from clinics to molecular genetics.

Parasitol Res 2018 Dec 14. Epub 2018 Dec 14.

Small Animal Clinic, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Strongyloides stercoralis is a worldwide-distributed intestinal nematode affecting mainly humans and dogs. Canine strongyloidosis is generally characterised by diarrhoea, malabsorption and bronchopneumonia, and may be fatal in cases of impaired immunity. In recent years, molecular and epidemiological studies suggested that host-adapted populations of S. Read More

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December 2018

Out-of-home informal support important for medication adherence, diabetes distress, hemoglobin A1c among adults with type 2 diabetes.

J Behav Med 2018 Dec 14. Epub 2018 Dec 14.

Department of Family Medicine, University of Michigan, Ann Arbor, MI, USA.

Adults with type 2 diabetes mellitus (T2DM) often receive self-management support from adult children, siblings or close friends residing outside of their home. However, the role of out-of-home support in patients' self-management and well-being is unclear. Patients (N = 313) with HbA1c > 7. Read More

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December 2018

Reasons to stop drinking alcohol among patients with rheumatoid arthritis in Sweden: a mixed-methods study.

BMJ Open 2018 Dec 14;8(12):e024367. Epub 2018 Dec 14.

Spenshult Research and Development Center, Spenshult, Halmstad, Sweden.

Objectives: The aims were to identify patients with rheumatoid arthritis (RA) who had stopped drinking alcohol and compare them with patients drinking alcohol, and to explore reasons for stopping drinking alcohol.

Design: A sequential explanatory mixed methods design was used.

Setting: Six rheumatology clinics in Southern Sweden Better Anti-Rheumatic FarmacOTherapy cohort. Read More

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December 2018

Obinutuzumab pretreatment abrogates tumor lysis risk while maintaining undetectable MRD for venetoclax + obinutuzumab in CLL.

Blood Adv 2018 Dec;2(24):3566-3571

Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.

Early data on venetoclax-containing regimens for the treatment of chronic lymphocytic leukemia (CLL) show promising results with deep remissions, but are hampered by potential risk for tumor lysis syndrome (TLS). Whether optimal duration of venetoclax treatment can be guided by minimal residual disease (MRD) is currently unknown. To study whether TLS risk can be mitigated in an unfit population by introducing preinduction, and whether MRD-guided duration of venetoclax treatment is a feasible and efficacious approach, we performed the Dutch-Belgian Cooperative Trial Group for Hemato-oncology (HOVON) 139/GIVE trial. Read More

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December 2018

Redesigning primary care in the safety net: A qualitative analysis of team-based care implementation.

Healthc (Amst) 2018 Dec 11. Epub 2018 Dec 11.

University of California San Francisco, Center for Vulnerable Populations, Division of General Internal Medicine, United States.

Background: Team-based care is an innovative approach to primary care in which groups of health care professionals work collaboratively to manage care for groups of patients. Safety-net organizations face specific barriers to implementing health care innovations. More research is needed that documents the dynamics that inform implementation and sustainment of innovative practices in the safety net. Read More

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December 2018

Knee MRI Primary Care Ordering Practices for Nontraumatic Knee Pain: Compliance With ACR Appropriateness Criteria and Its Effect on Clinical Management.

J Am Coll Radiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.

Purpose: To evaluate the appropriateness of MRI ordering practices and their effect on clinical management for nontraumatic knee pain at the primary care clinics of a large public urban hospital.

Materials And Methods: In all, 196 consecutive MRIs for nontraumatic knee pain ordered from primary care clinics in a large public urban hospital over an 18-month period were studied. ACR Appropriateness Criteria (AC) scores for nontraumatic knee pain were retrospectively calculated from medical record reviews. Read More

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December 2018

Toward an enhanced understanding of psychological resilience for HIV youth populations.

AIDS Care 2018 Dec 14:1-4. Epub 2018 Dec 14.

a SC SmartState Center for Healthcare Quality, Department of Health Promotion, Education, and Behavior, Arnold School of Public Health , University of South Carolina , Columbia , USA.

Though mother-to-child HIV transmission has been dramatically reduced in the past decade, there are currently an estimated 1.8 million children living with HIV across the globe, and over 30% of all new HIV infections occur among youth ages 15-25. While all youth experience developmental challenges, children and adolescents who are living with HIV must navigate these challenges within the context of high HIV stigma and must cope with a host of psychosocial and health-related challenges. Read More

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December 2018

Validity of a two-item screen for early psychosis.

Psychiatry Res 2018 Dec 3;270:861-868. Epub 2018 Nov 3.

Department of Psychology, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA. Electronic address:

Well-validated screening tools have been developed to identify people at high risk for psychosis, but these are rarely used outside of specialty clinics or research settings. The development of extremely brief and simple screening tools could increase dissemination, especially in settings with low buy-in such as those with low base rates of psychosis and/or time constraints. We sought to identify such a brief measure by modeling participant responses to three psychosis screening questionnaires (Prime Screen; Prodromal Questionnaire-Brief; Youth Psychosis At Risk Questionnaire) in a sample of 139 help-seeking individuals and 335 college students (age range: 12-25). Read More

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December 2018

Usefulness of pre-travel medical examination and vaccination.

Authors:
Hiroshi Watanabe

Nihon Rinsho 2016 Dec;74(12):2047-2051

At present, both the number of Japanese travelers to foreign countries and foreign travel- ers who visit Japan are remarkably increasing. Travel clinic for travelers is well-known in western countries and medical consultation, vaccination, prescription, etc are performed, but that is not popular in Japan yet. Most Japanese travelers to foreign countries do not necessa- rily collect any information concerning the infectious diseases which are endemic in the des- tination and security related with their travel and hesitates to receive the recommended vac- cines or prophylactic for malaria. Read More

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December 2016

Attitudes of Nephrology Nurses Toward Patient Exercise During Hemodialysis.

Nephrol Nurs J 2016 Jul-Aug;43(4):331-337

Senior Research Fellow at Eastern Health-Deakin University Nursing and Midwifery Research Centre, Victoria, Australia.

Exercise programs are rare in hemodialysis clinics. The study goals were to 1) explore nephrology nurses' attitudes toward exercise; 2) compare the attitudes between nephrology nurses who had been exposed and those who had not been exposed to an patient exercise program; and 3) measure the psychometric properties of a survey tool to measure nephrology nurses' attitudes toward intradialytic exercise. Nephrology nurse attitudes were positive toward patients' exercising; however, they did not believe it was their responsibility to conduct the exercise program. Read More

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December 2018

Which patients initiate cognitive processing therapy and prolonged exposure in department of veterans affairs PTSD clinics?

J Anxiety Disord 2018 Nov 20;62:53-60. Epub 2018 Nov 20.

Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Department of Medicine, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA; Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454, USA; Department of Psychology, University of Minnesota, 75 E River Rd, Minneapolis, MN 55455, USA. Electronic address:

The United States Department of Veterans Affairs (VA) provides Cognitive Processing Therapy (CPT) and Prolonged Exposure therapy (PE) for PTSD at all of its facilities, but little is known about systematic differences between patients who do and do not initiate these treatments. VA administrative data were analyzed for 6,251 veterans receiving psychotherapy over one year in posttraumatic stress disorder (PTSD) specialty clinics at nine VA medical centers. CPT and PE were initiated by 2,173 (35%) patients. Read More

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November 2018

Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013-2015: inpatients and outpatients.

Int J Infect Dis 2018 Dec 11. Epub 2018 Dec 11.

Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Background: Hand, foot and mouth disease (HFMD) has been associated with large outbreaks among young children, including severe illness and fatality, in the Asia-Pacific Region since 1997. Severe illness is often associated with enterovirus A71 (EV-A71). Vietnam experienced a large sustained outbreak of 200. Read More

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December 2018
1 Read

Access to Dermatology Services at Free Medical Clinics, A Nationwide Cross-sectional Survey.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Institute of Public and Preventative Health, Augusta University. Electronic address:

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December 2018
2 Reads

Enhancing smoking cessation in Mexico using an e-Health tool in primary healthcare.

Salud Publica Mex 2018 Sep-Oct;60(5):549-558

Department of Biomedical Research, Medical Center, Hackensack University. Hackensack, NJ, US.

Objective: To evaluate an e-Health tool designed to enhance smoking cessation in Mexico in primary healthcare.

Materials And Methods: Smokers 18 years of age and older were recruited in the waiting room of two primary healthcare clinics in Mexico City. Participants used an eHealth smoking cessation tool that included smoking-related assessments, education on pharmacotherapy, and motivational videos. Read More

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December 2017

High prevalence of binge drinking among people living with HIV in four African countries.

J Int AIDS Soc 2018 Dec;21(12):e25202

Service de maladies infectieuses et tropicales, CRCF, CHU de Fann, Dakar, Sénégal.

Introduction: Excessive alcohol consumption leads to unfavourable outcomes in people living with HIV (PLHIV), including reduced adherence to antiretroviral therapy (ART) and engagement into care. However, there is limited information on alcohol consumption patterns among PLHIV in sub-Saharan Africa.

Methods: Using a cross-sectional approach, the Alcohol Use Disorders Identification Test (AUDIT-C) was administered to PLHIV attending HIV clinics in Côte d'Ivoire, Togo, Senegal and Zambia (2013 to 2015). Read More

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December 2018
2 Reads

Dual Therapy Coating on Micro/Nanoscale Porous Polyetheretherketone to Eradicate Biofilms and Accelerate Bone Tissue Repair.

Macromol Biosci 2018 Dec 14:e1800376. Epub 2018 Dec 14.

School of Chemical Engineering, Sichuan University, Chengdu, 610065, China.

Defective osteogenesis and latent infections continue to be two major issues in the therapy of bone tissue regeneration. In this study, a unique hierarchically micro/nanoscale-architecture is first proposed and produced on polyetheretherketone (PEEK). Besides, a "simvastatin-PLLA film-tobramycin microspheres" delivery system is subsequently fabricated to endow the PEEK implant with osteogenic and antibacterial capabilities. Read More

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December 2018

Validation of CollaboRATE and SURE - two short questionnaires to measure shared decision making during CPAP initiation.

J Sleep Res 2018 Dec 13:e12808. Epub 2018 Dec 13.

Department of Clinical Neurophysiology, Linköping University Hospital, Linköping, Sweden.

Adherence to continuous positive airway pressure (CPAP) treatment tends to be low. Brief validated instruments focusing on shared decision making have not been used in a CPAP context. The aim was to investigate factorial structure, categorical functioning of the response scale and differential item functioning across sub-populations of the CollaboRATE and Sure questionnaires among patients with obstructive sleep apnea (OSA) before CPAP treatment is initiated. Read More

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December 2018

Primary signet-ring stromal tumour of the testis: case report with literature review.

APMIS 2019 Jan;127(1):45-49

Institute of Pathology, University of Göttingen, Göttingen, Germany.

Primary signet-ring stromal tumour of the testis (PSRSTT) is a very rare type of primary testicular tumour, which is not actually mentioned in the current WHO categorization of tumours of the male genital organs. In this case we report about histologically and immunohistochemically features of this rare tumour. In the present case, PSRTT was found in the orchiectomy preparation of a 69-year-old man with painless swelling of his left testicle. Read More

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January 2019

Ornithine aminotransferase promoted the proliferation and metastasis of non-small cell lung cancer via upregulation of miR-21.

J Cell Physiol 2018 Dec 13. Epub 2018 Dec 13.

Department of Respiratory Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

The incidence and mortality of lung cancer ranked the first among all types of cancer in China, and non-small cell lung cancer (NSCLC) is the most common type of lung cancer accounting for 85% of all lung cancers. Given that the survival rate of patients with advanced NSCLC is still poor nowadays, identification of novel therapeutic targets and the development of effective therapies are desired for the treatment of NSCLC in clinics. In this study, we reported the upregulation of ornithine aminotransferase (OAT) in NSCLC cells and clinical tumor samples as well as its association with the advanced TNM stage, metastasis, and poor tumor differentiation of lung cancer. Read More

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December 2018

Applicability of telemedicine in the screening of diabetic retinopathy (DR): The first multicentre study in Italy. The No Blind Study.

Diabetes Metab Res Rev 2018 Dec 13:e3113. Epub 2018 Dec 13.

Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.

Aims: Diabetic retinopathy (DR) represents the main cause of blindness among adults in the industrialized Countries. Use of telemedicine could offer an easy, smart specialist fundus oculi examination, as well as putting in a screening program many patients who otherwise would be excluded.

Materials And Methods: The NO Blind is a transversal, multicentre, observational study. Read More

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December 2018

Mortality and losses to follow-up among adolescents living with HIV in the IeDEA global cohort collaboration.

J Int AIDS Soc 2018 Dec;21(12):e25215

TREAT Asia/amfAR, The Foundation for AIDS Research, Bangkok, Thailand.

Introduction: We assessed mortality and losses to follow-up (LTFU) during adolescence in routine care settings in the International epidemiology Databases to Evaluate AIDS (IeDEA) consortium.

Methods: Cohorts in the Asia-Pacific, the Caribbean, Central, and South America, and sub-Saharan Africa (Central, East, Southern, West) contributed data, and included adolescents living with HIV (ALHIV) enrolled from January 2003 and aged 10 to 19 years (period of adolescence) while under care up to database closure (June 2016). Follow-up started at age 10 years or the first clinic visit, whichever was later. Read More

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December 2018

Epidemiology of Facial Fractures among Older Adults: A Retrospective Analysis of a Nationwide Emergency Department Database.

Dent Traumatol 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthodontics, The University of Illinois in Chicago, Chicago, Illinois.

Background/aims: The prevalence of facial fractures among older adults has increased in recent years, and nationwide studies about the epidemiological profile and outcomes of hospital-based ED visits for facial fractures among older adults are scarce. The aim of this study was to provide USA-wide data of hospital-based Emergency Department (ED) visits for facial fractures among older adults, and to investigate the outcomes associated with these visits.

Material And Methods: The Nationwide Emergency Department Sample (NEDS) for the years 2008 to 2014 was used for the present study. Read More

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December 2018

Comparison of Health-Related Quality of Life Between Adjuvant Breast Cancer Treatment Groups.

Oncol Nurs Forum 2019 Jan;46(1):59-70

Bastyr University.

Objectives: To compare the health-related quality of life (HRQOL) of women who did (receivers, n = 372) and did not (intentional nonreceivers, n = 46) receive all recommended adjuvant treatments for breast cancer.

Sample & Setting: Women were recruited through integrative oncology clinics and the Cancer Surveillance System registry in western Washington.

Methods & Variables: A cross-sectional and correlational study using secondary data was conducted. Read More

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January 2019

Cytoreductive prostatectomy: what is the evidence? A systematic review.

Minerva Urol Nefrol 2018 Dec 14. Epub 2018 Dec 14.

Urology Department, Sant'Andrea Hospital, Università degli Studi di Roma « La Sapienza », Rome, Italy.

Introduction: Cytreductive prostatectomy is an experimental surgical approach to metastatic prostate cancer (mPCa), with the scope of improving local symptoms and potentially ameliorate oncologic outcomes. Aim of the current systematic review is to analyze available evidence to support this approach and explore published data a future trial on cytoreductive prostatectomy.

Evidence Acquisition: A systematic review was conducted searching all relevant studies published in PubMed, EMBASE, Cochrane Library, CINAHL, Google Scholar and Ovid database until August 1, 2018. Read More

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December 2018

A rare case of intracardiac fibrosarcoma with myxoid features inducing venous occlusion in a dog - a case report.

BMC Vet Res 2018 Dec 14;14(1):398. Epub 2018 Dec 14.

Department of Pathology, University of Agricultural Sciences and Veterinary Medicine "Ion Ionescu de la Brad", Iași, Romania.

Background: In both humans and animals, cardiac fibrosarcoma is rare among primary cardiac malignant neoplasia. The overall prevalence of cardiac neoplasia in dogs is low, reported to be between 0.17% and 0. Read More

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December 2018
1 Read

Frequency and features of nocturnal enuresis in Pakistani children aged 5 to 16 years based on ICCS criteria: a multi-center cross-sectional study from Karachi, Pakistan.

BMC Fam Pract 2018 Dec 14;19(1):198. Epub 2018 Dec 14.

South Tyneside District Hospital, South Shields, UK.

Background: Nocturnal enuresis (NE) is a common symptom in children worldwide. International Children's Continence Society (ICCS) defines enuresis as either mono-symptomatic, NE with lower urinary tract symptoms and NE with co-morbid conditions. The objectives of this study were to determine the frequencies and types of NE and associated symptoms and conditions in children aged 5 to 16 years based on ICCS criteria. Read More

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December 2018

Unroofed coronary sinus detected by 2D/3D echocardiography in a patient referred to catheter ablation for atrial fibrillation.

J Cardiol Cases 2016 Oct 8;14(4):111-114. Epub 2016 Aug 8.

Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.

A 67-year-old female visited our echo lab for a preoperative screening exam before radiofrequency catheter ablation for atrial fibrillation. Transthoracic echocardiography revealed abnormal color flow signal in the right atrium, and following 2D/3D transesophageal echocardiography proved partial type of unroofed coronary sinus. Absence of associated congenital abnormalities was ruled out by Doppler and contrast echo examinations. Read More

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October 2016

Infertility patients' need and preferences for online peer support.

Reprod Biomed Soc Online 2018 Aug 15;6:80-89. Epub 2018 Nov 15.

Jewish General Hospital, Department of Psychiatry, Montreal, Quebec, Canada.

This study sought to determine the level of interest in online peer support among infertility patients, factors associated with such interest, and preferences for features of an online peer support network. A sample of 236 men and 283 women ( = 519) seeking fertility treatment were recruited from four clinics in Ontario and Quebec, Canada. Participants completed an anonymous online questionnaire assessing demographics, perceived stress and fertility characteristics, in addition to interest in and preferences for online infertility peer support. Read More

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August 2018
2 Reads

Providers' Involvement of Parents, Families, and Family Dynamics in Youth Weight Management Programs.

Glob Pediatr Health 2018 4;5:2333794X18817134. Epub 2018 Dec 4.

East Carolina University, Greenville, NC, USA.

Family-based interventions are the current standard for the treatment of pediatric obesity, yet the details of how providers are involving family members, and the barriers to family involvement, are largely unknown. The objective of this study is to describe how providers in pediatric weight management (PWM) involve family members, identify barriers to family involvement, and how they address challenging family dynamics. A cross-sectional survey was administered to PWM centers/clinics and their providers in the United States and Canada. Read More

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December 2018

Risk Factors for Short- and Long-Term Outcomes in Children With STEC-HUS/D HUS: A Single-Center Experience.

Glob Pediatr Health 2018 4;5:2333794X18816920. Epub 2018 Dec 4.

The Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.

. Hemolytic uremic syndrome (HUS) is one of the common causes for acute kidney injury in childhood. . Read More

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December 2018

An AI-Based Heart Failure Treatment Adviser System.

IEEE J Transl Eng Health Med 2018 23;6:2800810. Epub 2018 Nov 23.

Computer Science DepartmentThe University of Texas at DallasRichardsonTX75080USA.

Management of heart failure is a major health care challenge. Healthcare providers are expected to use best practices described in clinical practice guidelines, which typically consist of a long series of complex rules. For heart failure management, the relevant guidelines are nearly 80 pages long. Read More

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November 2018

Improvements in self-care among patients with diabetes in a remote island in Japan: a pilot study.

J Rural Med 2018 Nov 29;13(2):134-140. Epub 2018 Nov 29.

Minamidaito Village Office, Japan.

The traits of the inhabitants of rural areas could affect clinical improvements. In the rural areas of Japan, a feeling of competitiveness often exists between the members of a community; this competitiveness could prompt patients to exert efforts in improving their health. This study aimed to assess the effects of competitiveness on the clinical outcomes of patients with diabetes. Read More

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November 2018

Light intensity output of visible light communication units and clinicians' knowledge and attitude among Riyadh private clinics.

J Conserv Dent 2018 Nov-Dec;21(6):667-670

Department of Restorative, College of Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.

Background: With the evolution of bonded restorations, visible light-curing units became inseparable from the practice of dentistry. This study was designed to evaluate light intensity output of light-emitting diode (LED) units used in private clinics in Riyadh, Saudi Arabia, and to investigate dentists' knowledge and attitude regarding the usage of light-curing units.

Methodology: Two hundred randomly selected LED units' light intensity output was evaluated using Demetron LED Radiometer-Kerr among evenly distributed private clinics in Riyadh, Saudi Arabia. Read More

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December 2018

Captive to the Clinic: Phase I Clinical Trials as Temporal Total Institutions.

Sociol Inq 2018 Nov 20;88(4):724-748. Epub 2018 Apr 20.

This article develops the concept of to describe how and why individuals voluntarily submit to highly-controlled and often dehumanizing environments. We focus empirically on Phase I clinical trials, which offer compensation to healthy people in exchange for testing investigational pharmaceuticals. Analyzing the experiences of 67 U. Read More

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November 2018

Meta-Analysis Comparing the Incidence of Infective Endocarditis Following Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement.

Am J Cardiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Medicine Division of Cardiovascular Medicine, University of Iowa Hospitals and Clinics, Iowa, Iowa.

Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) is a rare but life-threatening complication. Paravalvular regurgitation, compression of native leaflets, and space between transcatheter valve prosthesis and native valves could dispose TAVI recipients at increased risk of IE compared with SAVR. To assess the comparative risk of IE between TAVI and SAVR, we performed a systematic review and meta-analysis. Read More

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December 2018

Advancing pharmacological treatments for opioid use disorder (ADaPT-OUD): protocol for testing a novel strategy to improve implementation of medication-assisted treatment for veterans with opioid use disorders in low-performing facilities.

Addict Sci Clin Pract 2018 Dec 13;13(1):25. Epub 2018 Dec 13.

Center for Innovation to Implementation, Palo Alto Health Care System, 795 Willow Rd, MC152, Palo Alto, CA, 94304, USA.

Background: In the US, emergency room visits and overdoses related to prescription opioids have soared and the rates of illicit opioid use, including heroin and fentanyl, are increasing. Opioid use disorder (OUD) is associated with higher morbidity and mortality, higher HIV and HCV infection rates, and criminal behavior. Opioid agonist therapy (OAT; methadone and buprenorphine) is proven to be effective in treating OUD and decreasing its negative consequences. Read More

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December 2018

The evaluation of nocturia in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia and the analysis of the curative effect after medical or placebo therapy for nocturia: a randomized placebo-controlled study.

BMC Urol 2018 Dec 13;18(1):115. Epub 2018 Dec 13.

Department of Urology, Beijing Huairou Hospital, Beijing, 101400, China.

Background: To study nocturia in patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) after medical or placebo treatment.

Methods: Patients with LUTS suggestive of BPH from several community clinics were included. Patients completed the International Prostate Symptom Score (I-PSS) questionnaire and a 3-day voiding diary. Read More

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December 2018

[Possibilities of doctor-patient communication - understanding patients' expectations].

Orv Hetil 2018 Dec;159(50):2136-2143

Népegészségtani Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Dóm tér 10., 6720.

Introduction: Nowadays doctor-patient consultation is not limited to personal appointments, there are new technical possibilities to keep contact.

Aim: The aim of our study was to examine the way in which the doctor and patient interact with each other between two personal consultations and how the patients would like to reach their physicians when needed.

Method: Questionnaire survey was done among waiting patients in an outpatient clinic in Budapest. Read More

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December 2018

Future Implications of Using Registered Dietitians in Multidisciplinary Polycystic Ovary Syndrome Treatment.

Healthcare (Basel) 2018 Dec 8;6(4). Epub 2018 Dec 8.

Department of Human Nutrition and Foods, West Virginia University, Morgantown, WV 26506, USA.

Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder in females with insulin resistance playing a key role in pathogenesis. The objective of this study was to investigate current trends and future implications of multidisciplinary PCOS clinics with inclusion of dietitians. A two-phase, formative investigation on practitioners was conducted through an anonymous survey followed by focus groups. Read More

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December 2018

Einschränkungen in der Gehfähigkeit und der Sprunggelenksdorsalflexion bei Kindern nach intensiver Krebsbehandlung.

Klin Padiatr 2018 Dec 13. Epub 2018 Dec 13.

Department of Molecular and Cellular Sports Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.

Background: With improved survival rates in pediatric oncology, the detection of adverse side- and late-effects is gaining increased interest. This cross-sectional study investigated walking abilities and ankle dorsiflexion function in children with cancer.

Patients: Study participants included 16 children with various cancers (4-20 years, patient group) after completion of the intense treatment and 16 age- and gender-matched healthy peers (comparison group). Read More

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December 2018

GRIN2A-related disorders: genotype and functional consequence predict phenotype.

Brain 2018 Dec 12. Epub 2018 Dec 12.

Institute of Human Genetics, University of Leipzig Hospitals and Clinics, Leipzig, Germany.

Alterations of the N-methyl-d-aspartate receptor (NMDAR) subunit GluN2A, encoded by GRIN2A, have been associated with a spectrum of neurodevelopmental disorders with prominent speech-related features, and epilepsy. We performed a comprehensive assessment of phenotypes with a standardized questionnaire in 92 previously unreported individuals with GRIN2A-related disorders. Applying the criteria of the American College of Medical Genetics and Genomics to all published variants yielded 156 additional cases with pathogenic or likely pathogenic variants in GRIN2A, resulting in a total of 248 individuals. Read More

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December 2018

In-silico pelvis and sacroiliac joint motion-A review on published research using numerical analyses.

Clin Biomech (Bristol, Avon) 2018 Dec 6;61:95-104. Epub 2018 Dec 6.

Department of Anatomy, University of Otago, Dunedin, New Zealand; Department of Trauma, Orthopedic and Plastic Surgery, University Hospital of Leipzig, Germany; Orthopaedicus Clinics, Leipzig, Germany.

Background: Computational models of the human pelvis have become highly useful tools to assess mechanisms of injury, diagnostics and treatment options. The purpose of this systematic literature review was to summarize existing pelvic computer models, to assess their comparability and the measures taken for experimental validation.

Methods: Research on virtual simulations of the posterior pelvis and sacroiliac joint available from the ISI Web of Knowledge, PubMed and Scopus databases available until January 2018 were included. Read More

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December 2018
1 Read

The association between perceived injunctive norms toward corporal punishment, parenting support, and risk for child physical abuse.

Child Abuse Negl 2018 Dec 10;88:246-255. Epub 2018 Dec 10.

Tulane University, School of Public Health and Tropical Medicine, Department of Global Community Health and Behavioral Sciences, New Orleans, LA, 70112, USA.

The use of corporal punishment (CP) is a strong risk factor for many poor outcomes for children including child maltreatment. The use of CP occurs within social contexts which are important to understand. Although it is known that perceived social norms regarding CP are related to its use, the specific role that a mother's primary support person plays in influencing attitudes toward and use of CP remains unknown. Read More

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December 2018

Exercise therapy in addition to an orthosis reduces pain more than an orthosis alone in patients with thumb base osteoarthritis: a propensity score matching study.

Arch Phys Med Rehabil 2018 Dec 10. Epub 2018 Dec 10.

Dept. of Plastic, Reconstructive and Hand Surgery, Erasmus Medical Center Rotterdam, the Netherlands; Dept. of Rehabilitation Medicine, Erasmus Medical Center Rotterdam, the Netherlands.

Objective: To compare the effect of exercises and orthotics with orthotics alone on pain and hand function in patients with thumb base (CMC-1) osteoarthritis (OA) and to predict outcomes on pain and hand function of exercises and orthotics.

Design: Prospective cohort study with propensity score matching SETTING: Data collection took place in thirteen outpatient clinics for hand surgery and hand therapy in the Netherlands.

Participants: A consecutive, population-based sample of 173 patients with CMC-1 OA was included in this study of which 84 were matched on baseline demographics and baseline primary outcomes. Read More

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December 2018

The potential of reducing AST testing in hospital settings.

Clin Biochem 2018 Dec 10. Epub 2018 Dec 10.

Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada; McMaster University Medical Centre, Hamilton Health Sciences, Hamilton, Ontario, Canada.

Background: Aspartate aminotransferase (AST) is regularly ordered with alanine aminotransferase (ALT) to assess liver integrity. In many situations, AST testing provides little or no added clinical value, since ALT is more specific and the both enzyme activities highly correlate. The objective of this study is to determine the potential reduction in AST testing, if not performed when ALT results are within reference intervals (RI). Read More

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December 2018

Enhancement of drug electrotransfer by extracellular plasmid DNA.

Arch Biochem Biophys 2018 Dec 10. Epub 2018 Dec 10.

Biophysical Research Group, Vytautas Magnus University, Kaunas, Lithuania. Electronic address:

Electroporation is a widely established method for molecular delivery across electric field perturbed plasma membrane. It can be used as a non-viral DNA transfection method, or as a way to achieve small molecule delivery to or extraction from cells. We examined the possibility of combining the DNA delivery to the cells with small molecule transport across electroporated plasma membrane. Read More

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December 2018

The demographics of vaccine hesitancy in Shanghai, China.

PLoS One 2018 13;13(12):e0209117. Epub 2018 Dec 13.

Department of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.

Background: Vaccine hesitancy has been little studied in low- and middle-income countries but is a potential concern because vaccine refusal may increase the burden of infectious diseases and impede control efforts. The aim of this study was to compare vaccine hesitancy between locals, long-time city residents, and non-locals, who have more recently moved to the city from either other urban or rural areas, in Shanghai, China.

Methods: Parents of infants ≤3 months of age were surveyed at immunization clinics in Shanghai, China. Read More

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December 2018