126,835 results match your criteria Clinics Sao Paulo Brazil[Journal]


The addition of silver affects the deformation mechanism of a twinning-induced plasticity steel: Potential for thinner degradable stents.

Acta Biomater 2019 Apr 17. Epub 2019 Apr 17.

Laboratory for Biomaterials and Bioengineering, Canada Research Chair I in Biomaterials and Bioengineering for the Innovation in Surgery, Department of Min-Met-Materials Engineering, Research Center of CHU de Quebec, Division of Regenerative Medicine, Laval University, Quebec City, QC G1V 0A6, Canada. Electronic address:

While Fe-based alloys have already been reported to possess all mechanical properties required for vascular stenting, their relatively low degradation rate in vivo still constitutes their main bottleneck. The inflammatory reaction generated by a stent is inversely proportional to its mass. Therefore, the tendency in stenting is to lower the section so to reduce the inflammatory reaction. Read More

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http://dx.doi.org/10.1016/j.actbio.2019.04.030DOI Listing

Voice aerodynamics following office-based hyaluronate injection laryngoplasty.

Clin Otolaryngol 2019 Apr 20. Epub 2019 Apr 20.

School of Medicine, Chang Gung University, Taoyuan 333, Taiwan; 259 Wen-Hwa 1st Road, Taoyuan, 333, Taiwan.

Objectives: Neuromuscular control, glottal conformation, and aerodynamics are the major factors affecting voice performance. We aimed to characterize the degree to which voice improvements following office-based intracordal hyaluronate injection laryngoplasty (HIL) depend on changes in voice aerodynamics in patients with unilateral vocal fold paralysis (UVFP), by assessing the correlations between these parameters.

Design: Prospective case series. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/coa.13343
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http://dx.doi.org/10.1111/coa.13343DOI Listing
April 2019
1 Read

Sex-related differences in patients undergoing surgery for shoulder instability: a Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability cohort study.

J Shoulder Elbow Surg 2019 Apr 16. Epub 2019 Apr 16.

University of Kentucky Orthopaedic Surgery and Sports Medicine, Lexington, KY, USA.

Hypothesis And Background: Male sex has been identified as a risk factor for both primary shoulder dislocation and recurrent instability, and male patients more often undergo surgery for instability. Despite published discrepancies between sexes regarding the incidence and surgical rates of shoulder instability, there is little detail on the differences in presentation, mechanism of injury, and intraoperative findings. The purpose of this study was to explore these differences. Read More

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http://dx.doi.org/10.1016/j.jse.2019.02.020DOI Listing

The Impact of Social Determinants of Health on Hospitalization in the Veterans Health Administration.

Am J Prev Med 2019 Apr 16. Epub 2019 Apr 16.

Center for Population Health IT, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Introduction: This study aims to assess the effect of individual and geographic-level social determinants of health on risk of hospitalization in the Veterans Health Administration primary care clinics known as the Patient Aligned Care Team.

Methods: For a population of Veterans enrolled in the primary care clinics, the study team extracted patient-level characteristics and healthcare utilization records from 2015 Veterans Health Administration electronic health record data. They also collected census data on social determinants of health factors for all U. Read More

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http://dx.doi.org/10.1016/j.amepre.2018.12.012DOI Listing

Case study projects by a Korean national research agency: Past 12 years and future.

Complement Ther Clin Pract 2019 May 16;35:48-52. Epub 2019 Jan 16.

Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, NC, 27710, USA. Electronic address:

Objectives: Scientific rigor is a known challenge to establish in heavily individualized practices of traditional medicine. A national research agency in Korea carried out a 12-year project to promote case reports among clinics of Korean Medicine (KM). This report aims at providing challenges, achievements, and thoughts for future endeavors. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.01.007DOI Listing

Complementary medicines use amongst elective surgery patients at a public tertiary hospital: A prospective observational cohort study in Australia.

Complement Ther Clin Pract 2019 May 15;35:284-289. Epub 2019 Mar 15.

School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin University, Perth, Australia. Electronic address:

Background: and purpose. Complementary medicines (CM) use may result in untoward effects perioperatively. The study purpose is to identify CM pattern of use amongst elective surgery patients, and improve effectiveness of information collection relating to CM use. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.03.012DOI Listing

Preconception Care in the Veterans Health Administration.

Semin Reprod Med 2018 Nov 19;36(6):327-339. Epub 2019 Apr 19.

VA Central Office, Women's Health Services, Washington, District of Columbia.

Preconception care (PCC), defined as a set of interventions to help women optimize their health and well-being prior to pregnancy, can improve pregnancy outcomes and is recommended by national organizations including the Centers for Disease Control and Prevention and the American College of Obstetricians and Gynecologists. Women Veterans who use the Department of Veterans Affairs (VA) health care system may face elevated risks of adverse pregnancy and birth outcomes due to a high prevalence of chronic medical and mental health conditions as well as psychosocial stressors including sexual trauma history and intimate partner violence. Many women Veterans of childbearing age experience poverty and homelessness, which are key social determinants of poor reproductive health outcomes. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678753
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http://dx.doi.org/10.1055/s-0039-1678753DOI Listing
November 2018
1 Read

Abortion Providers' experiences and views on self-managed medication abortion, an exploratory study.

Contraception 2019 Apr 16. Epub 2019 Apr 16.

University of Iowa Hospitals and Clinics, Department of Obstetrics and Gynecology, 200 Hawkins Drive, Iowa City, IA, 52242.

Objective: Data on the practice of self-managed medication abortion are limited, in part because this practice takes place purposefully outside of established healthcare systems. Given this, we aimed to ascertain abortion providers' familiarity with self-managed medication abortion and associated complications, compare regional differences, and evaluate provider attitudes.

Study Design: We distributed an online survey to members of Society for Family Planning, Association of Reproductive Health Providers, and the Abortion Care Network between July and September 2017 querying experiences with and opinions about self-managed abortion. Read More

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http://dx.doi.org/10.1016/j.contraception.2019.04.006DOI Listing
April 2019
1 Read

Impact of malaria and hepatitis B co-infection on clinical and cytokine profiles among pregnant women.

PLoS One 2019 19;14(4):e0215550. Epub 2019 Apr 19.

West African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Legon- Accra, Ghana.

Background: The overlap of malaria and chronic hepatitis B (CHB) is common in endemic regions, however, it is not known if this co-infection could adversely influence clinical and immunological responses. This study investigated these interactions in pregnant women reporting to antenatal clinics in Ghana.

Methods: Clinical parameters (hemoglobin, liver function biomarker, peripheral malaria parasitemia, and hepatitis B viremia) and cytokine profiles were assayed and compared across four categories of pregnant women: un-infected, mono-infected with Plasmodium falciparum (Malaria group), mono-infected with chronic hepatitis B virus (CHB group) and co-infected (Malaria+CHB group). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215550PLOS

Assessing for Fetal Alcohol Spectrum Disorder.

J Popul Ther Clin Pharmacol 2019 Jan 23;26(1):e39-e55. Epub 2019 Jan 23.

Canada FASD Research Network.

Background The recommended "gold standard" for Fetal Alcohol Spectrum Disorder (FASD) assessment involves a multidisciplinary diagnostic team and comprehensive battery of neuropsychological tests to evaluate functioning across 10 brain domains. The current Canadian Guideline for diagnosis of FASD outlines a list of test measures for assessment; however, very little research exists to explore which specific tools are being used in clinical practice. Objectives The purpose of the current study was to gain a better understanding of the testing measures used by FASD clinicians in Alberta, Canada. Read More

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http://jptcp.com/index.php/jptcp/article/view/54
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http://dx.doi.org/10.22374/1710-6222.26.1.4DOI Listing
January 2019
1 Read

Predictors and variability of antibiotic prescribing amongst family physicians.

J Antimicrob Chemother 2019 Apr 19. Epub 2019 Apr 19.

Public Health Ontario, Toronto, Ontario, Canada.

Background: Rising rates of antimicrobial resistance are driven by overuse of antibiotics. Characterizing physician antibiotic prescribing variability can inform interventions to optimize antibiotic use.

Objectives: To describe predictors of overall antibiotic prescribing as well as the inter-physician variability in antibiotic prescribing amongst family physicians. Read More

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http://dx.doi.org/10.1093/jac/dkz112DOI Listing

Feasibility of pulmonary valve imaging using transesophageal echocardiography upper esophageal view.

Echocardiography 2019 Apr 19. Epub 2019 Apr 19.

Division of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.

Background: The present study designed to evaluate feasibility of transesophageal echocardiographic (TEE) imaging of the pulmonary valve (PV) at the transaortic upper esophageal (TAUE) window. We hypothesized that patients with larger aorta would be more likely to have visualization of the PV from this TAUE window.

Methods: 2D TEE images of the PV were prospectively acquired by one operator at the TAUE window looking through the aortic arch. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/echo.14332
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http://dx.doi.org/10.1111/echo.14332DOI Listing
April 2019
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Training Pediatric Residents in Literacy Promotion: Residency Directors' Perspectives.

Teach Learn Med 2019 Apr 19:1-8. Epub 2019 Apr 19.

a The Department of Pediatrics , Rutgers Robert Wood Johnson Medical School , New Brunswick , New Jersey , USA.

Phenomenon: The American Academy of Pediatrics and Canadian Pediatric Society recommend that pediatricians incorporate literacy promotion during well child care, but literacy promotion education during pediatric training remains understudied. We sought to understand how literacy promotion training is currently implemented in pediatric residency programs from the perspective of program directors. Approach: We conducted semistructured interviews with all 9 residency program directors in 1 state. Read More

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http://dx.doi.org/10.1080/10401334.2019.1598866DOI Listing
April 2019
1 Read

Patient-Centeredness during In-Depth Consultation in the Outpatient Clinic of a Tertiary Hospital in Korea: Paradigm Shift from Disease to Patient.

J Korean Med Sci 2019 Apr 22;34(15):e119. Epub 2019 Apr 22.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Background: Patient-centered care (PCC) and integrative care approach are widely advocated. However, their implementation usually requires an extended consultation time. Despite significant advances in medical diagnosis and treatment, no studies have examined consultation time and patient centeredness in Korea. Read More

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https://jkms.org/DOIx.php?id=10.3346/jkms.2019.34.e119
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http://dx.doi.org/10.3346/jkms.2019.34.e119DOI Listing
April 2019
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Healthcare Utilization and Treatment Patterns in Diabetic Macular Edema in Korea: a Retrospective Chart Review.

J Korean Med Sci 2019 Apr 22;34(15):e118. Epub 2019 Apr 22.

Department of Ophthalmology, Daegu Catholic University Medical Center, Daegu, Korea.

Background: Limited data exist on real-world treatment patterns for diabetic macular edema (DME) in Korea. In this study, we investigated DME treatment patterns from 2009 to 2014 and the impact of baseline treatment on healthcare resource utilization and visual acuity (VA) outcomes.

Methods: A retrospective cohort chart review of DME patients treated at 11 hospital ophthalmology clinics between January 1, 2012 and December 31, 2013 was conducted. Read More

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http://dx.doi.org/10.3346/jkms.2019.34.e118DOI Listing

Risks of substance uses, alcohol flush response, Helicobacter pylori infection and upper digestive tract diseases-An endoscopy cross-sectional study.

Kaohsiung J Med Sci 2019 Apr 18. Epub 2019 Apr 18.

Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

This study examines the effects of environmental hazards, including tobacco, alcohol/alcohol flush response, areca nut, and Helicobacter pylori (H pylori) infection on upper digestive diseases. This is a multi-hospital-based endoscopy-survey cross-sectional study. Subjects were received upper endoscopies in outpatient clinics at four hospitals in Taiwan between 2008 and 2013. Read More

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http://dx.doi.org/10.1002/kjm2.12071DOI Listing

Swedish Quality Registry for Caries and Periodontal Diseases - a framework for quality development in dentistry.

Int Dent J 2019 Apr 18. Epub 2019 Apr 18.

Public Dental Service, County Council of Värmland, Karlstad, Sweden.

Objectives: There is a need for monitoring dental health and healthcare, as support for quality development, allocation of resources and long-term planning of dental care. The aim of this paper is to describe the concept and implementation of the Swedish Quality Registry for Caries and Periodontal Diseases (SKaPa).

Materials And Methods: The SKaPa receives information by automatic transfer of data daily from electronic patient dental records via secure connections from affiliated dental care organisations (DCOs). Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/idj.12481
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http://dx.doi.org/10.1111/idj.12481DOI Listing
April 2019
1 Read

Student Exposure to Cancer Patients: an Analysis of Clinical Logbooks and Focus Groups in Clinical Year Medical Students.

J Cancer Educ 2019 Apr 17. Epub 2019 Apr 17.

Fiona Stanley Hospital, 11 Robin Warren Dr, Murdoch, WA, 6150, Australia.

Despite cancer being the leading cause of mortality, cancer education and patient exposure are lacking in many medical schools. The aim of this study was to evaluate the nature of cancer patient exposure, relative to the clinical setting for medical students on placement and to explore their experiences. Participants were asked to maintain a logbook of cancer patient encounters and were invited to attend a structured focus group upon completion of the academic year. Read More

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http://dx.doi.org/10.1007/s13187-019-01526-1DOI Listing

Gene expression analysis of follicular cells revealed inflammation as a potential IVF failure cause.

J Assist Reprod Genet 2019 Apr 18. Epub 2019 Apr 18.

Centre de recherche en reproduction, développement et santé intergénérationnelle (CRDSI), Université Laval, 2440 Boulevard Hochelaga, Québec, QC, G1V 0A6, Canada.

Purpose: Hormonal stimulation prior to IVF influences the ovarian environment and therefore impacts oocytes and subsequent embryo quality. Not every patient has the same response to the same treatment and many fail for unknown reasons. Knowing why a cycle has failed and how the follicles were affected would allow clinicians to adapt the treatment accordingly and improve success rate. Read More

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http://dx.doi.org/10.1007/s10815-019-01447-4DOI Listing

Preparation and Evaluation of Liposomes Co-Loaded with Doxorubicin, Phospholipase D Inhibitor 5-Fluoro-2-Indolyl Deschlorohalopemide (FIPI) and D-Alpha Tocopheryl Acid Succinate (α-TOS) for Anti-Metastasis.

Nanoscale Res Lett 2019 Apr 18;14(1):138. Epub 2019 Apr 18.

Institute of Medicinal Biotechnology, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

Tumor metastasis has become a key obstacle to cancer treatment, which causes high mortality. Nowadays, it involves multiple complex pathways, and conventional treatments are not effective due to fewer targets. The aims of the present study were to construct a novel liposome delivery system co-loading a specific PLD inhibitor 5-fluoro-2-indolyldes-chlorohalopemide (FIPI) in combination with antitumor drug doxorubicin (DOX) and functional excipient D-alpha tocopheryl acid succinate (α-TOS) for anti-metastasis. Read More

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http://dx.doi.org/10.1186/s11671-019-2964-4DOI Listing

[Simulation techniques in surgical training programs to become an orthopedic and trauma surgeon : Introduction to the topic].

Authors:
Christian Willy

Unfallchirurg 2019 Apr 18. Epub 2019 Apr 18.

Klinik für Unfallchirurgie, Orthopädie, Septisch-Rekonstruktive Chirurgie, Forschungs- und Behandlungszentrum Rekonstruktion von Defektwunden, Bundeswehrkrankenhaus Berlin, Scharnhorststr. 13, 10115, Berlin, Deutschland.

Numerous professional and societal developments nowadays fundamentally reduce the possibility of mastering all officially prescribed surgical training contents in sufficient quantities and in a target-oriented manner with sufficient operative internal clinical experience from the surgical daily routine. In order to learn key competences, modern simulation technology will have to be integrated into surgical training programs. A meaningful implementation requires a structured procedure for the users, individual clinics or surgical training networks. Read More

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http://dx.doi.org/10.1007/s00113-019-0647-3DOI Listing

A Longitudinal Analysis of Total Pain Scores for a Panel of Patients Treated by Pain Clinics.

Health Serv Res Manag Epidemiol 2019 Jan-Dec;6:2333392818788420. Epub 2019 Apr 8.

Florida Hospital Pain Medicine, Orlando, FL, USA.

Background: There is a critical necessity to identify psychometric properties of the total pain score as a measurement of pain management effectiveness in the clinic.

Purpose: In this article, we perform the analysis of the global pain scores from a panel of patients treated by 10 pain management physicians in a single group practice.

Basic Procedures: The pain measurement consists of 4 pain subscales, namely physical pain, emotions, clinical outcome, and activities. Read More

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http://journals.sagepub.com/doi/10.1177/2333392818788420
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http://dx.doi.org/10.1177/2333392818788420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454651PMC
April 2019
1 Read

Intestinal Perforation in ACTH-Dependent Cushing's Syndrome.

Biomed Res Int 2019 13;2019:9721781. Epub 2019 Mar 13.

Division of Endocrinology and Metabolism, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred more frequently in patients with ectopic ACTH syndrome and in those with a greater than 10-fold elevation of 24-hour urinary free cortisol level. Read More

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http://dx.doi.org/10.1155/2019/9721781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436364PMC

Applying Machine Learning of Erythrocytes Dynamic Antigens Store in Medicine.

Front Mol Biosci 2019 3;6:19. Epub 2019 Apr 3.

Computer Science Department, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia.

Erythrocytes Dynamic Antigens Store (EDAS) is a new discovery. EDAS consists of self-antigens and foreign (non-self) antigens. In patients with infectious diseases or malignancies, antigens of infection microorganism or malignant tumor exist in EDAS. Read More

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https://www.frontiersin.org/article/10.3389/fmolb.2019.00019
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http://dx.doi.org/10.3389/fmolb.2019.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456707PMC
April 2019
1 Read

Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea.

SAGE Open Med 2019 8;7:2050312119842268. Epub 2019 Apr 8.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Objective: To evaluate sleep disturbances in a diverse, contemporary HIV-positive patient cohort and to identify demographic, clinical, and immune correlates.

Methods: A convenience sample of 176 patients from a racially and ethnically diverse HIV-positive patient cohort in an urban population. This was a cross-sectional, epidemiologic study. Read More

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http://dx.doi.org/10.1177/2050312119842268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454647PMC
April 2019
1 Read

Adult Mental Health Outpatients Who Have Minor Children: Prevalence of Parents, Referrals of Their Children, and Patient Characteristics.

Front Psychiatry 2019 2;10:163. Epub 2019 Apr 2.

Health Services Research, SINTEF, Trondheim, Norway.

A strong connection exists between parental mental illness and lifetime mental health risk for their children. Thus, it is important to determine, when parents attend for treatment for their illness, the prevalence and characteristics of parents with a mental illness and identify referral actions for their children. Previous studies indicate that 12-45% of adult mental health service patients are parents with minor children. Read More

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http://dx.doi.org/10.3389/fpsyt.2019.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456127PMC

Retrospective Study of Patients with Hyperphenylalaninemia- Experience from a Tertiary Care Center in Pakistan.

J Pak Med Assoc 2019 Apr;69(4):509-513

Department of Paediatrics and Child Health, Aga Khan University, Karachi.

Objective: To assess the clinical and biochemical features as well as outcome of hyperphenylalaninemia patients.

Methods: The descriptive retrospective study was conducted at the Aga Khan University Hospital, Karachi, and comprised data from January 2013 to February 2017 of plasma amino acid analysed at the Biochemical Genetic Laboratory of patients with phenylalanine levels >120 umol/L. Medical charts of patients registered with the Metabolic Clinics were reviewed, while outside referrals were contacted by telephone to collect data on a pre-structured questionnaire. Read More

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April 2019
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Raised levels of IFN-gamma and IL-13 are associated with pre-diabetes amongst newly diagnosed patients with Tuberculosis.

J Pak Med Assoc 2019 Apr;69(4):468-473

Indus Hospital, Karachi.

Objective: To investigate pre-diabetes and diabetes in newly-diagnosed tuberculosis patients and to assess the association of serum cytokine levels with diabetes status.

Methods: The cross-sectional study was conducted at Indus Hospital and The Aga Khan University Hospital, Karachi from May to November 2015, and included patients of either gender aged 18 years or more with a confirmed diagnosis of tuberculosis who were either newly diagnosed or had received up to 1 month of anti-tuberculosis therapy were included. Patients were enrolled from among those presenting to the clinics at Indus Hospital, Karachi, and the Department of Medicine, Aga Khan University Hospital (AKUH), Karachi. Read More

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April 2019
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Tobacco-related knowledge following a comprehensive tobacco-free workplace program within behavioral health facilities: Identifying organizational moderators.

Patient Educ Couns 2019 Apr 10. Epub 2019 Apr 10.

University of Houston, Department of Psychological, Health, and Learning Sciences, Houston, USA; University of Houston, HEALTH Research Institute, Houston, USA. Electronic address:

Objective: Although smoking prevalence rates among behavioral health consumers is nearly five times that of the general population, evidence-based policies and practices to address tobacco use are uncommon within behavioral health settings. This study assessed changes in non-clinical, general staff and clinician tobacco-related knowledge following brief education provided as part of a comprehensive tobacco-free workplace program implementation and explored organizational moderators of pre- to post-education knowledge change.

Methods: Fifteen behavioral health facilities, comprising hundreds of individual clinics in Texas, participated in a one (for general staff) or two (for clinicians) hour educational session. Read More

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http://dx.doi.org/10.1016/j.pec.2019.04.013DOI Listing

A case study on implantation strategies to mitigate coronary obstruction in a patient receiving transcatheter aortic valve replacement.

J Biomech 2019 Apr 12. Epub 2019 Apr 12.

Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA; Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, USA. Electronic address:

Coronary obstruction is a life threatening complication during and post-transcatheter aortic valve replacement (TAVR). The objective of this preliminary work is to investigate the mechanisms underlying coronary obstruction in a patient after TAVR, in whom coronary obstruction was confirmed in addition to highlighting the importance of pre-procedural planning. The aortic root of an 80-year old male patient with coronary obstruction during TAVR-where a 29 mm SAPIEN 3 was deployed-was segmented from Computed Tomography scans and 3D-printed with compliant material. Read More

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http://dx.doi.org/10.1016/j.jbiomech.2019.04.010DOI Listing

Dirofilaria repens in dogs and humans in Lithuania.

Parasit Vectors 2019 Apr 18;12(1):177. Epub 2019 Apr 18.

Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, Vileikos str. 8, LT-44404, Kaunas, Lithuania.

Background: In Lithuania, the first case of canine subcutaneous dirofilariosis was recorded in 2010. Since then, an increasing number of cases of canine dirofilariosis have been documented in different veterinary clinics throughout the country. Human dirofilariosis was diagnosed in Lithuania for the first time in September 2011. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13071-019-3406-yDOI Listing
April 2019
1 Read

Costs of implementing and sustaining enhanced collaborative care programs involving community partners.

Implement Sci 2019 Apr 18;14(1):37. Epub 2019 Apr 18.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Box 356560, Seattle, WA, 98195-6560, USA.

Background: Collaborative care is an evidence-based program for treating depression in primary care. We sought to expand this model by recruiting clinics interested in incorporating community partners (i.e. Read More

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http://dx.doi.org/10.1186/s13012-019-0882-6DOI Listing

Predictors associated with HIV/AIDS patients dropout from antiretroviral therapy at Mettu Karl Hospital, southwest Ethiopia.

Authors:
Melaku Tadege

BMC Res Notes 2019 Apr 18;12(1):232. Epub 2019 Apr 18.

Department of Statistics, Injibara University, Injibara, Amhara, Ethiopia.

Objective: The aim of this study was to determine the major risk factors of antiretroviral therapy dropout. The retrospective cohort research design was applied. 1512 HIV patients were included from Mettu Karl Hospital in Illubabor Zone, southwest part of Ethiopia from September 2005 to January 2018. Read More

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http://dx.doi.org/10.1186/s13104-019-4267-3DOI Listing

Surgical termination of pregnancy for fetal anomaly: what role can an independent abortion service provider play?

J Obstet Gynaecol 2019 Apr 19:1-6. Epub 2019 Apr 19.

c British Pregnancy Advisory Service , Stratford Upon Avon , UK.

Most hospitals in Great Britain only offer a medical termination of pregnancy for a fetal anomaly (TOPFA) in the second trimester. We describe the safety and acceptability of a surgical TOPFA service delivered by an independent-sector abortion provider. Non-identifiable data for women undergoing TOPFA at British Pregnancy Advisory Service from 1 January 2015 to 31 March 2016 was extracted from existing databases. Read More

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http://dx.doi.org/10.1080/01443615.2019.1568973DOI Listing

Engaging Patients in Primary Care Quality Improvement Initiatives: Facilitators and Barriers.

Am J Med Qual 2019 Apr 18:1062860619842938. Epub 2019 Apr 18.

2 University of Wisconsin-Madison, Madison, WI.

Health care transformation calls for patient engagement in quality improvement (PEQI), yet practice participation remains low. This pilot study of 8 primary care clinics at 7 statewide locations sought to determine the most effective strategies for disseminating a previously successful single-system PEQI intervention. Qualitative data were obtained through site visits, interviews, observations, and journaling. Read More

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http://dx.doi.org/10.1177/1062860619842938DOI Listing

Rural Latino health and the built environment: a systematic review.

Ethn Health 2019 Apr 19:1-26. Epub 2019 Apr 19.

b Department of Public Health Sciences , Clemson University , Clemson , USA.

Objective: This study systematically reviewed literature examining the influence of the rural built environment on Latinos' health outcomes and behaviour in the United States. A secondary aim of the study was to identify strategies developed to address challenges in the rural built environment affecting Latinos' health.

Design: This study followed the reporting guidelines set forth by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Read More

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https://www.tandfonline.com/doi/full/10.1080/13557858.2019.1
Publisher Site
http://dx.doi.org/10.1080/13557858.2019.1606899DOI Listing
April 2019
1 Read

PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells.

Prostate 2019 Apr 18. Epub 2019 Apr 18.

Cancer Biology and Genetics, Queen's Cancer Research Institute, Queen's University, Kingston, Canada.

Background: Accumulating evidence shows that tumor cell-specific genomic changes can influence the cross talk between cancer cells and the surrounding tumor microenvironment (TME). Loss of the PTEN tumor suppressor gene is observed in 20% to 30% of prostate cancers (PCa) when first detected and the rate increases with PCa progression and advanced disease. Recent findings implicate a role for PTEN in cellular type I interferon response and immunosuppression in PCa. Read More

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http://dx.doi.org/10.1002/pros.23808DOI Listing

Corneal Endothelial Decompensation after Ocular Chemical Burn: Description of a New Finding.

Klin Monbl Augenheilkd 2019 Apr 18;236(4):371-376. Epub 2019 Apr 18.

Augenklinik, Universitatsspital Basel, Basel, Switzerland.

Background: Ocular chemical burn is an ophthalmological emergency. Therefore, chemical injuries should be promptly addressed in order to initiate the appropriate treatment as soon as possible and optimize the visual prognosis. We present a retrospective study of ten cases with ocular chemical burn including one with superglue and one with a liquid plaster material injury and describe their clinical course. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0857-6538
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http://dx.doi.org/10.1055/a-0857-6538DOI Listing
April 2019
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Changes in chemsex and sexual behaviour over time, among a cohort of MSM in London and Brighton: Findings from the AURAH2 study.

Int J Drug Policy 2019 Apr 15;68:54-61. Epub 2019 Apr 15.

UCL Centre for Population research in Sexual Health and HIV, Institute for Global Health, UCL, London, United Kingdom. Electronic address:

Background: Recent evidence has suggested that chemsex (the use of mephedrone, crystal methamphetamine and γ -hydroxybutyrate/ γ -butryolactone (GHB/GBL) to enable, enhance and prolong sexual interactions) has increased among men having sex with men (MSM) attending sexual health clinics in large UK cities. To date there has been no data from the UK or Europe that describes changes in chemsex over time within a cohort of MSM.

Methods: The prospective cohort study, Attitudes to and Understanding Risk of Acquisition of HIV over Time (AURAH2), collected online questionnaire data from HIV negative or undiagnosed MSM (at enrolment) from 2015 to 2018, recruited from sexual health clinics. Read More

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http://dx.doi.org/10.1016/j.drugpo.2019.03.021DOI Listing

Akebia Saponin D inhibits the formation of atherosclerosis in ApoE mice by attenuating oxidative stress-induced apoptosis in endothelial cells.

Atherosclerosis 2019 Apr 10;285:23-30. Epub 2019 Apr 10.

Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China. Electronic address:

Background And Aims: Akebia Saponin D (ASD) is a major bioactive triterpenoid saponin compound isolated from the Chinese herb Dipsacus asper wall (DSW). DSW has been long used as an anti-Alzheimer disease and anti-osteoporosis agent in clinics. However, anti-atherosclerotic effects of ASD have not been fully investigated. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.04.202DOI Listing
April 2019
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Automated in vivo screen in zebrafish identifies clotrimazole as targeting a metabolic vulnerability in a melanoma model.

Dev Biol 2019 Apr 15. Epub 2019 Apr 15.

Laboratory of Experimental Cancer Biology, CIBIO Department, University of Trento, Via Sommarive 9, 38123 Povo TN, Italy. Electronic address:

Therapeutic approaches for cutaneous melanoma are flourishing, but despite promising results, there is an increasing number of reported primary or secondary resistance to the growing sets of drugs approved for therapy in the clinics. Combinatorial approaches may overcome resistance, as they may tackle specific weaknesses of melanoma cells, not sufficient on their own, but effective in combination with other therapies. The transgenic zebrafish line kita:ras develops melanoma with high frequency. Read More

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http://dx.doi.org/10.1016/j.ydbio.2019.04.005DOI Listing

Exosomes on the border of species and kingdom intercommunication.

Transl Res 2019 Mar 29. Epub 2019 Mar 29.

Consorcio Regenero, Chilean Consortium for Regenerative Medicine, Santiago, Chile; Cells for Cells, Santiago, Chile; Laboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de los Andes, Santiago, Chile. Electronic address:

Over the last decades exosomes have become increasingly popular in the field of medicine. While until recently they were believed to be involved in the removal of obsolete particles from the cell, it is now known that exosomes are key players in cellular communication, carrying source-specific molecules such as proteins, growth factors, miRNA/mRNA, among others. The discovery that exosomes are not bound to intraspecies interactions, but are also capable of interkingdom communication, has once again revolutionized the field of exosomes research. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19315244193007
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http://dx.doi.org/10.1016/j.trsl.2019.03.008DOI Listing
March 2019
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Factors associated with uncontrolled asthma in adult asthmatics in Kinshasa, Democratic Republic of Congo.

PLoS One 2019 18;14(4):e0215530. Epub 2019 Apr 18.

Department of Epidemiology and Biostatistics, School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of Congo.

Background: The ultimate goal of asthma treatment is long-term control. Uncontrolled asthma is a major public health problem worldwide, but there is a lack of data on asthma control and its causes in the Democratic Republic of Congo (DRC).

Objective: To determine the socio-demographic, environmental, clinical, and biological factors and comorbidities associated with uncontrolled adult asthma in Kinshasa, DRC. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215530PLOS

The role of the transition clinic from pediatric to adult inflammatory bowel disease care.

Curr Opin Gastroenterol 2019 Apr 16. Epub 2019 Apr 16.

Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, Ohio, USA.

Purpose Of Review: The transition of patients from pediatric to adult centered care represents not only the means to transfer medical care to a group of providers who specialize in adult care but also is part of the process of the transfer of healthcare responsibility from the family to a patient. The intent of this review is to provide a summary of some of the important studies published in the past 2 years that advance this knowledge.

Recent Findings: Progress has been made in the recognition of the process of transition, including developing tools to assess transition readiness, improving routes of communication along with patient education. Read More

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http://Insights.ovid.com/crossref?an=00001574-900000000-9920
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http://dx.doi.org/10.1097/MOG.0000000000000535DOI Listing
April 2019
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Obtaining and Modeling Variability in Travel Times From Off-Site Satellite Clinics to Hospitals and Surgery Centers for Surgeons and Proceduralists Seeing Office Patients in the Morning and Performing a To-Follow List of Cases in the Afternoon.

Anesth Analg 2019 Apr 15. Epub 2019 Apr 15.

From the Department of Anesthesiology, Pain Management and Perioperative Medicine, University of Miami, Miami, Florida.

Background: Hospitals achieve growth in surgical caseload primarily from the additive contribution of many surgeons with low caseloads. Such surgeons often see clinic patients in the morning then travel to a facility to do 1 or 2 scheduled afternoon cases. Uncertainty in travel time is a factor that might need to be considered when scheduling the cases of to-follow surgeons. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004148DOI Listing

Screening for hypertension: an elevated office blood pressure measurement is valuable, adding an automated one is even better.

Blood Press Monit 2019 Apr 16. Epub 2019 Apr 16.

Department of Nusing, Université du Québec à Trois-Rivières, Trois-Rivières.

Background: Previous studies have examined the relevance of hypertension (HTN) screening in walk-in clinics. So far, no valid algorithm has been proposed on how to integrate HTN screening in this context. The aim of our study was to assess, in a walk-in clinic setting, the HTN screening strategy for performing an automated office blood pressure (AOBP) measurement following an initially high office blood pressure (OBP) measurement. Read More

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http://dx.doi.org/10.1097/MBP.0000000000000382DOI Listing

Conscience and Religious Freedom Division Marks Its First Anniversary with Action.

Authors:
Sandra H Johnson

Hastings Cent Rep 2019 Mar;49(2):4-5

In January 2018, the Trump administration established the Conscience and Religious Freedom Division within the Department of Health and Human Services' Office of Civil Rights with the explicit goal of intensifying legal protection of religious and conscience objections in health care. The establishment of OCR's new division illustrates the significant powers of administrative agencies to mold the substance of law without seeking legislative action. The mere formation of a division dedicated to protecting conscience rights is already having a significant impact; it is causing health care entities, including hospitals, research organizations, and clinics, to change policies and practices to comply with the declared enforcement strategy. Read More

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http://doi.wiley.com/10.1002/hast.986
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http://dx.doi.org/10.1002/hast.986DOI Listing
March 2019
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Implementing Web-Based Interventions in HIV Primary Care Clinics: Pilot Implementation Evaluation of Positive Health Check.

JMIR Form Res 2019 Apr 18;3(2):e10688. Epub 2019 Apr 18.

Center for Communication Science, RTI International, Durham, NC, United States.

Background: Web-based interventions can help people living with HIV achieve better clinical outcomes and behaviors, but integrating them into clinical practice remains challenging. There is a gap in understanding the feasibility of implementing these interventions in HIV clinic settings from the clinicians' perspective.

Objective: The goal of the research was to determine whether Positive Health Check (PHC)-a Web-based, tailored video counseling tool focused on increasing patient adherence and retention in care and reducing HIV risk among HIV-positive patients-was acceptable, appropriate, and feasible for HIV primary care clinic staff to implement in clinic workflows. Read More

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http://dx.doi.org/10.2196/10688DOI Listing