Clin Exp Dermatol 2018 Jan 8. Epub 2018 Jan 8.
Department ofDermatology, Medical School of Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China.
: The prevalence of anxiety and depression is significantly higher in individuals with psoriasis than in the general population. Clinical data also show that anti-anxiety and antidepression drugs can reduce skin lesions in patients with psoriasis, but the actual mechanism is still poorly understood.Aim
: To investigate whether brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrKB) signalling plays a role in the mechanism underlying psoriasis with depression and anxiety behaviours. Read More