1,732 results match your criteria Clinical and Experimental Optometry [Journal]


Optical coherence tomography: seeing the unseen.

Clin Exp Optom 2019 May;102(3):193-194

Optometrist in Private Practice, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/cxo.12902DOI Listing

Re: Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Clin Exp Optom 2019 Apr 24. Epub 2019 Apr 24.

School of Medicine, Dentistry and Biomedical Science, Queen's University of Belfast, Belfast, UK.

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http://dx.doi.org/10.1111/cxo.12906DOI Listing

Response to Re: Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Clin Exp Optom 2019 Apr 24. Epub 2019 Apr 24.

Optometry and Vision Science, Flinders University, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1111/cxo.12911DOI Listing

Multiple bilateral choroidal metastases in stage IV lung cancer.

Authors:
Cari L Nealon

Clin Exp Optom 2019 Apr 21. Epub 2019 Apr 21.

Optometry Section, Louis Stokes Cleveland Veterans Affairs Medical Centre, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1111/cxo.12907DOI Listing

Case of paediatric steroid-induced glaucoma showing extremely fast progression with deformation of lamina cribrosa.

Clin Exp Optom 2019 Apr 17. Epub 2019 Apr 17.

Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/cxo.12908DOI Listing

Optical coherence tomography in paediatric clinical practice.

Clin Exp Optom 2019 May 15;102(3):300-308. Epub 2019 Apr 15.

Department of Ophthalmology, The University of Melbourne, Melbourne, Victoria, Australia.

Optical coherence tomography is a non-invasive ocular imaging technique that is frequently used in the diagnosis and monitoring of optic nerve or retinal disease. Advances in optical coherence tomography speed and image processing capability allow increased use of the modality in clinical practice, especially in younger children. This review outlines the challenges involved in imaging children, highlights the technological progress, the importance of acquiring normative data and, finally, focuses on the clinical applicability of optical coherence tomography in our paediatric population with various ocular conditions. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cxo.12909
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http://dx.doi.org/10.1111/cxo.12909DOI Listing
May 2019
2 Reads

Atypical junctional scotoma secondary to optic chiasm atrophy: a case report.

Clin Exp Optom 2019 Apr 4. Epub 2019 Apr 4.

Advanced Care Ocular Disease Service, Southern College of Optometry, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1111/cxo.12903DOI Listing
April 2019
1 Read

Estimation of angle kappa and pupil barycentre configuration in myopic tilted disc syndrome.

Clin Exp Optom 2019 Mar 28. Epub 2019 Mar 28.

Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey.

Background: To evaluate the angle kappa and pupil barycentre configuration in patients with myopic tilted disc syndrome (TDS).

Methods: Thirty-five eyes of 35 patients with TDS were included in the study. Thirty-five eyes of 35 age- and sex-matched healthy subjects were enrolled in the control group. Read More

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http://dx.doi.org/10.1111/cxo.12897DOI Listing
March 2019
1 Read

Ex vivo evaluation of the stability, safety and antibacterial efficacy of an extemporaneous povidone-iodine preparation for ophthalmic applications.

Clin Exp Optom 2019 Mar 28. Epub 2019 Mar 28.

Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Background: Povidone-iodine is used as a cost-effective broad-spectrum antiseptic in the prophylaxis and treatment of certain ocular infections. In this study, the stability, ophthalmic irritation potential and antibacterial efficacy of an extemporaneous povidone-iodine preparation was determined using established ex vivo and in vitro assays.

Methods: Extemporaneous iodine was prepared by simple dilution in normal saline. Read More

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http://dx.doi.org/10.1111/cxo.12899DOI Listing

Quantification of corneal transparency in post-mortem human corneas using laser scatter image analysis.

Clin Exp Optom 2019 Mar 28. Epub 2019 Mar 28.

SCOPE, Vellore Institute of Technology, Vellore, India.

Background: The cornea is a highly transparent structure covering the anterior one-fifth of the eyeball. The suitability of post-mortem donor corneas for keratoplasty is currently qualitatively assessed. This makes inferences prone to bias and subjective variability. Read More

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http://dx.doi.org/10.1111/cxo.12898DOI Listing

Peripheral eye length measurement techniques: a review.

Clin Exp Optom 2019 Mar 20. Epub 2019 Mar 20.

Brien Holden Vision Institute, Sydney, New South Wales, Australia.

Along with the rising myopia epidemic is the increasing interest in any ocular parameter that might inform understanding of myopia progression. The relationship between eye length and myopia has long been established but the recent interest in the central and peripheral retina, eye shape, retinal contour, and refractive error development is attracting more clinical and research interest in peripheral eye length measurements. Therefore, peripheral eye length measurements are an important step in the ongoing research involving the peripheral retina. Read More

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http://dx.doi.org/10.1111/cxo.12892DOI Listing

Imaging choroidal knuckle.

Clin Exp Optom 2019 Mar 19. Epub 2019 Mar 19.

Aditya Birla Sankara Nethralaya, Kolkata, India.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cxo.12895
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http://dx.doi.org/10.1111/cxo.12895DOI Listing
March 2019
3 Reads

Corneal elevation changes after forced eyelid closure in healthy participants and in patients with keratoconus.

Clin Exp Optom 2019 Mar 18. Epub 2019 Mar 18.

Department of Ophthalmology, Eskişehir Osmangazi University Medical School, Eskişehir, Turkey.

Background: To assess pointwise corneal elevation changes after forced eyelid closure test (FECT) in the eyes of healthy subjects and in eyes with keratoconus.

Methods: Twenty-nine subjects with keratoconus and 31 healthy volunteers were evaluated. Patients with keratoconus who had corneal hydrops, apical scarring, corneal thickness ≤ 400 μm, ocular surface disease, contact lens wear on the examination day and a history of corneal cross-linking were excluded. Read More

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http://dx.doi.org/10.1111/cxo.12891DOI Listing
March 2019
1 Read

Four-year changes in corneal biomechanical properties in children.

Clin Exp Optom 2019 Mar 18. Epub 2019 Mar 18.

Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: To determine four-year changes of corneal biomechanical parameters in Iranian children aged seven to eleven years and their correlation with optical components.

Methods: In this four-year prospective cohort study, 468 children aged seven to eleven years who were initially evaluated in 2012 were re-evaluated in 2016-2017. Multi-stage stratified cluster sampling was applied. Read More

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http://dx.doi.org/10.1111/cxo.12890DOI Listing
March 2019
1.256 Impact Factor

Longitudinal changes in outer nuclear layer thickness in soft drusen and reticular pseudodrusen.

Clin Exp Optom 2019 Mar 18. Epub 2019 Mar 18.

Ophthalmology Department, Institut de la Màcula, Barcelona, Spain.

Background: Drusen are seen in the early and intermediate stages of age-related macular degeneration. A retrospective, two-year observational study at a tertiary centre was designed to assess outer nuclear layer thickness in different types of drusen.

Methods: Patients over 50 years of age with predominant soft drusen or reticular pseudodrusen were included in the study. Read More

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http://dx.doi.org/10.1111/cxo.12894DOI Listing
March 2019
2 Reads

Repeatability of wide-field choroidal thickness measurements using enhanced-depth imaging optical coherence tomography.

Clin Exp Optom 2019 May 18;102(3):327-334. Epub 2019 Mar 18.

Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia.

Background: To examine the repeatability of choroidal thickness measurements across a 55° field, in a sample of healthy young adults using wide-field enhanced-depth imaging optical coherence tomography.

Methods: High-resolution wide-field volumetric enhanced-depth imaging scans were obtained from the right eye of 27 adults (mean age 27 ± 5 years) during two sessions, separated by 19 ± 15 days, using the follow-up feature of the Spectralis instrument, while controlling for confounding factors known to influence choroidal thickness. Semi-automatic segmentation of the choroidal boundaries was corrected by a single masked observer. Read More

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http://dx.doi.org/10.1111/cxo.12893DOI Listing

Repeatability of two subjective accommodative amplitude measurements and agreement with an objective method.

Clin Exp Optom 2019 Mar 13. Epub 2019 Mar 13.

School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.

Background: The aim was to compare the repeatability of subjective accommodative amplitude (AA) measurements obtained using the modified push-up and minus-lens methods and determine the agreement with objective AA by an autorefractor.

Methods: The right eyes of 47 adults aged 22-30 years (mean 25.1 ± 1. Read More

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http://dx.doi.org/10.1111/cxo.12884DOI Listing

Long-term corneal multifocal stability following a presbyLASIK technique analysed by a light propagation algorithm.

Clin Exp Optom 2019 Mar 13. Epub 2019 Mar 13.

Department of R&D, Vissum Corporation, Alicante, Spain.

Background: There is a lack of scientific evidence on long-term follow-up of the outcomes of the presbyLASIK techniques. This study aimed to objectively evaluate corneal stability three years following excimer laser central presbyLASIK.

Methods: This is a longitudinal, retrospective, observation of a consecutive series of cases comprising 24 eyes which had been treated by central myopic or hyperopic Presbymax central presbyLASIK. Read More

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http://dx.doi.org/10.1111/cxo.12883DOI Listing
March 2019
1 Read

Corneal confocal microscopy: ready for prime time.

Clin Exp Optom 2019 Mar 4. Epub 2019 Mar 4.

Division of Research, Qatar Foundation, Weill Cornell Medicine-Qatar, Doha, Qatar.

Corneal confocal microscopy is a non-invasive ophthalmic imaging modality, which was initially used for the diagnosis and management of corneal diseases. However, over the last 20 years it has come to the forefront as a rapid, non-invasive, reiterative, cost-effective imaging biomarker for neurodegeneration. The human cornea is endowed with the densest network of sensory unmyelinated axons, anywhere in the body. Read More

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http://dx.doi.org/10.1111/cxo.12887DOI Listing
March 2019
1 Read
1.256 Impact Factor

Psychosocial assessment of potential retinal prosthesis trial participants.

Clin Exp Optom 2019 Mar 4. Epub 2019 Mar 4.

Centre for Eye Research Australia, The University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

Background: As the field of retinal prostheses advances, volunteers are required for device trials, and optimal participant recruitment is vital for intervention success. The aims of this study were: (i) to select tests that assess the psychosocial aspects of visual impairment and develop a psychosocial assessment protocol for persons who may be eligible for participation in retinal prostheses trials; (ii) to investigate correlations between these tests; and (iii) to determine associations between psychosocial factors and a person's interest in participating in a retinal prosthesis (bionic eye) trial.

Methods: Cross-sectional study of 72 adults with advanced retinal degeneration. Read More

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http://dx.doi.org/10.1111/cxo.12889DOI Listing
March 2019
3 Reads

The effect of cycloplegia on biometric measurements using swept-source optical coherence tomography-based biometry.

Clin Exp Optom 2019 Mar 4. Epub 2019 Mar 4.

Haydarpasa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Background: To evaluate the effect of pupil dilation obtained with cyclopentolate on biometric measurements using swept-source optical coherence tomography biometry.

Methods: This study involved 63 eyes of 63 healthy volunteers. After ophthalmic examination, biometry measurements of the participants were obtained with IOL Master 700 (Carl Zeiss Meditec AG, Jena, Germany). Read More

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http://dx.doi.org/10.1111/cxo.12888DOI Listing

Reproducibility in measuring tear samples using a freezing point depression osmometer.

Clin Exp Optom 2019 Feb 28. Epub 2019 Feb 28.

Departamento de Física Aplicada (Area de Optometría), Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain.

Background: Hyperosmolarity of tear fluid has been recognised as a common feature of all types of dry eye disease. This study was designed to assess the inter-session reproducibility of a freezing point depression osmometer (Fiske 110) as the most common and precise way of measuring osmolality, by using two different volumes of tear samples on healthy subjects, and to determine the possible applications of this device in tear film research and clinical practice.

Methods: Measurements were made by using the Fiske 110 osmometer under two different tear sample volumes (4 μl and 2 μl). Read More

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http://dx.doi.org/10.1111/cxo.12886DOI Listing
February 2019
3 Reads

Optical biometry in a commercially available anterior and posterior segment optical coherence tomography device.

Authors:
Piotr Kanclerz

Clin Exp Optom 2019 Feb 22. Epub 2019 Feb 22.

Hygeia Clinic, Gdańsk, Poland.

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http://dx.doi.org/10.1111/cxo.12880DOI Listing
February 2019

The effects of reflected glare and visual field lighting on computer vision syndrome.

Clin Exp Optom 2019 Feb 25. Epub 2019 Feb 25.

Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.

Background: Computer vision syndrome is common and affects performance of visual tasks. Background illumination, light source, light compensation, position of the display, contrast and glare are environmental factors associated with computer vision syndrome. The aim of this study is to investigate the effects of reflected glare and visual field lighting on computer vision syndrome. Read More

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http://dx.doi.org/10.1111/cxo.12878DOI Listing
February 2019

What if we didn't have a journal?

Authors:
Nathan Efron

Clin Exp Optom 2019 Mar;102(2):97-98

School of Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

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http://dx.doi.org/10.1111/cxo.12863DOI Listing

Could adoption of the rural pipeline concept redress Australian optometry workforce issues?

Clin Exp Optom 2019 Feb 23. Epub 2019 Feb 23.

Deakin Optometry, School of Medicine, Deakin University, Geelong, Victoria, Australia.

People living in rural and remote areas have poorer ocular health outcomes compared with those living in metropolitan areas. Reasons for this are multiple and complex but access to care is consistently reported as a defining factor. The geographic maldistribution of eye-care professionals is a major obstacle for regional, rural and remote Australians seeking care. Read More

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http://dx.doi.org/10.1111/cxo.12873DOI Listing
February 2019
1 Read

Optical coherence tomography imaging in keratoconus.

Clin Exp Optom 2019 May 22;102(3):218-223. Epub 2019 Feb 22.

Ophthalmology, Royal Victorian Eye and Ear Hospital, Centre for Eye Research Australia, The University of Melbourne, Melbourne, Victoria, Australia.

Optical coherence tomography (OCT) is being increasingly used as a tool in the diagnosis and management of keratoconus. While elevation-based topography remains essential, there is an expanding role for cross-sectional OCT imaging in the diagnosis of the disease. Images and measurements of corneal thickness, and in particular, epithelial thickness, may be important in diagnosing early cases, and following procedures such as intrastromal corneal ring segments, corneal transplants and corneal collagen cross-linking. Read More

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http://dx.doi.org/10.1111/cxo.12874DOI Listing

Aflibercept therapy in eyes with neovascular age-related macular degeneration and its effect on choroidal thickness.

Clin Exp Optom 2019 Feb 22. Epub 2019 Feb 22.

Department of Ophthalmology, Çukurova University Faculty of Medicine, Adana, Turkey.

Background: The purpose of this study was to investigate changes in best-corrected visual acuity (BCVA), central macular thickness (CMT) and subfoveal choroidal thickness (SCT) after intravitreal aflibercept injections for neovascular age-related macular degeneration (NV-AMD).

Methods: Eighty-nine eyes (48 treatment naive, 41 resistant) were included in this prospective study. All patients were treated with three consecutive monthly injections then every two months as required. Read More

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http://dx.doi.org/10.1111/cxo.12877DOI Listing
February 2019

Bacillary layer detachment: a novel optical coherence tomography finding as part of blunt eye trauma.

Clin Exp Optom 2019 May 21;102(3):343-344. Epub 2019 Feb 21.

Ophthalmology Department, Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

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http://dx.doi.org/10.1111/cxo.12876DOI Listing

Investigation of the relationship between macular pigment levels and rod-mediated dark adaptation in intermediate age-related macular degeneration.

Clin Exp Optom 2019 Feb 21. Epub 2019 Feb 21.

Vision Science Research Group, Department of Optometry and Vision Science, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, UK.

Background: It has been shown that rod-mediated dark adaptation is significantly delayed in ageing, a change which is exacerbated in age-related macular degeneration (AMD). Levels of lutein and zeaxanthin, the two main constituents of macular pigment have been found in rod outer segments, indicating that the macular pigment may have an influence on rod-mediated dark adaptation. The aim of this study was to determine if rod-mediated dark adaptation is associated with central macular pigment levels in individuals with intermediate stage AMD. Read More

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http://dx.doi.org/10.1111/cxo.12882DOI Listing
February 2019

Aniseikonia and anisometropia: implications for suppression and amblyopia.

Clin Exp Optom 2019 Feb 21. Epub 2019 Feb 21.

School of Optometry and Vision Science, The University of Auckland, Auckland, New Zealand.

Aniseikonia is a difference in the perceived size or shape of images between eyes, and can arise from a variety of physiological, neurological, retinal, and optical causes. Aniseikonia is associated with anisometropia, as both anisometropia itself and the optical correction for anisometropia can cause aniseikonia. Image size differences above one to three per cent can be clinically symptomatic. Read More

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http://dx.doi.org/10.1111/cxo.12881DOI Listing
February 2019
1 Read

An algorithm to identify the aetiology of crystalline retinopathy.

Clin Exp Optom 2019 Feb 21. Epub 2019 Feb 21.

Eye Clinic, Providence VA Medical Center, Providence, Rhode Island, USA.

Due to the extensive differential diagnoses and overlapping clinical features, determining the aetiology of a crystalline retinopathy can be challenging. More effective ways are needed to help clinicians isolate the cause of a crystalline retinopathy and determine the appropriate management of concomitant ocular and/or systemic disease. This paper reviews literature on crystalline retinopathy focusing upon the key features of each aetiology, including medical history, laterality, and examination findings. Read More

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http://dx.doi.org/10.1111/cxo.12879DOI Listing
February 2019

Alpha -adrenoceptor agonists inhibit form-deprivation myopia in the chick.

Clin Exp Optom 2019 Jan 30. Epub 2019 Jan 30.

Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: The putative myopia-controlling receptor is thought to be muscarinic acetylcholine receptor subtype M , because mamba toxin-3 can inhibit form-deprivation myopia in chicks at a far lower concentration than atropine. However, mamba toxin-3 is equally potent at the human α -, α -, and α -adrenoceptors. To test the hypothesis that α-adrenoceptors might be involved in regulation of eye growth, the treatment effects of α -adrenoceptor agonists brimonidine, clonidine, and guanfacine, and antagonist yohimbine, on form-deprivation myopia in the chick were measured. Read More

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http://dx.doi.org/10.1111/cxo.12871DOI Listing
January 2019

Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Clin Exp Optom 2019 Jan 29. Epub 2019 Jan 29.

Optometry and Vision Science, Flinders University, Adelaide, South Australia, Australia.

Background: Although being the second most common sight-threatening retinal vascular disease after diabetic retinopathy, the patient-centred impact of retinal vein occlusion has not been well studied. This study aims to understand the quality of life issues in people with retinal vein occlusion using a qualitative methodology.

Methods: In-depth semi-structured interviews were conducted with 17 patients with retinal vein occlusion. Read More

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http://dx.doi.org/10.1111/cxo.12875DOI Listing
January 2019
1 Read

Ocular and visual discomfort associated with smartphones, tablets and computers: what we do and do not know.

Clin Exp Optom 2019 Jan 21. Epub 2019 Jan 21.

School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia.

Smartphone and tablet use in Australia and worldwide is reaching saturation levels and associated visual and ocular discomfort such as headaches, eyestrain, dry eyes and sore eyes are widespread. This review synthesises the available literature and considers these symptoms in the context of a binocular vision and/or ocular surface aetiology. Eye discomfort with smartphones and tablets is discussed alongside similar symptoms reported with desktop computer use. Read More

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http://dx.doi.org/10.1111/cxo.12851DOI Listing
January 2019
3 Reads

Evaluation of tear meniscus dimensions using anterior segment optical coherence tomography in video terminal display workers.

Clin Exp Optom 2019 Jan 17. Epub 2019 Jan 17.

Department of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

Background: To evaluate tear meniscus height and tear meniscus area measured by optical coherence tomography (OCT) and to determine the prevalence of dry eye disease in video display terminal (VDT) users.

Methods: This was a case-control study performed on VDT users. The case group consisted of 53 subjects who vocationally use VDT more than six hours per day and the control group consisted of 49 subjects who used VDT not more than one hour per day. Read More

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http://doi.wiley.com/10.1111/cxo.12872
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http://dx.doi.org/10.1111/cxo.12872DOI Listing
January 2019
12 Reads

Normal-tension glaucoma: managing a case of mistaken identity.

Authors:
Dan Samaha

Clin Exp Optom 2019 Jan 16. Epub 2019 Jan 16.

School of Optometry, University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/cxo.12870DOI Listing
January 2019
1 Read

Anterior segment optical coherence tomography and its clinical applications.

Clin Exp Optom 2019 May 12;102(3):195-207. Epub 2019 Jan 12.

Faculty of Medicine and Health, Save Sight Institute, The University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.

Anterior segment optical coherence tomography (AS-OCT) has become one of the cornerstones of non-contact imaging modalities for assessing such structures as the cornea, anterior chamber angle, aqueous outflow pathway, sclera, and ocular surface structures. As such, it has a broad range of clinical applications, which have been independently reported in the literature. This paper aims to present a review of extant literature on the utility of AS-OCT and its efficacy in clinical applications, and to evaluate the quality of available evidence. Read More

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http://doi.wiley.com/10.1111/cxo.12869
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http://dx.doi.org/10.1111/cxo.12869DOI Listing
May 2019
9 Reads

Molecular evidence for the role of inflammation in dry eye disease.

Clin Exp Optom 2019 Jan 10. Epub 2019 Jan 10.

Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.

Ocular surface inflammation is propagated by a complex series of molecular processes and has been implicated in the pathogenesis of dry eye disease (DED), either as a causal or a downstream effect of ocular surface disease. A state of hyperosmolarity elicits an acute immune response in DED, leading to subsequent activation of the adaptive immune response. This cascade incites dysregulation of the immune system, triggering a vicious cycle of events that causes damage to the ocular surface. Read More

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http://doi.wiley.com/10.1111/cxo.12849
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http://dx.doi.org/10.1111/cxo.12849DOI Listing
January 2019
7 Reads

Multimodal imaging in perifoveal exudative vascular anomalous complex with co-existent diabetic retinopathy.

Clin Exp Optom 2019 Jan 8. Epub 2019 Jan 8.

Deptartment of Retina and Vitreous, Narayana Nethralaya, Benguluru, India.

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http://dx.doi.org/10.1111/cxo.12868DOI Listing
January 2019
1 Read

Latanoprostene bunod ophthalmic solution 0.024%: a new treatment option for open-angle glaucoma and ocular hypertension.

Clin Exp Optom 2019 Jan 7. Epub 2019 Jan 7.

Schwartz Laser Eye Center, Scottsdale, Arizona, USA.

Latanoprostene bunod (LBN) ophthalmic solution 0.024% is a novel, once-daily, nitric oxide-donating prostaglandin analogue for the lowering of intraocular pressure (IOP) in patients with open-angle glaucoma and ocular hypertension. The IOP-lowering actions of LBN are mediated by dual mechanisms of the molecule for increasing aqueous humour outflow. Read More

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http://dx.doi.org/10.1111/cxo.12853DOI Listing
January 2019
3 Reads

Factors influencing the choice of low-vision devices for visual rehabilitation in Stargardt disease.

Clin Exp Optom 2018 Dec 24. Epub 2018 Dec 24.

Department of Vitreoretinal Diseases, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

Background: Stargardt disease is the most common cause of juvenile macular degeneration leading to early central visual loss. Dispensing of correct low-vision devices based on the residual visual function and specific visual requirements of a patient can result in a positive outcome. It is important to know the factors involved in the selection of these devices. Read More

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http://dx.doi.org/10.1111/cxo.12867DOI Listing
December 2018
1 Read

Choroidal changes in human myopia: insights from optical coherence tomography imaging.

Clin Exp Optom 2019 May 19;102(3):270-285. Epub 2018 Dec 19.

School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia.

The choroid is a vascular tissue which plays a range of critical roles in the normal physiology of the eye, such as supplying the outer retina with oxygen and nutrients and the regulation of intraocular pressure. There is also substantial evidence, particularly from animal studies, that the choroid plays an important role in the regulation of eye growth and the development of common refractive errors like myopia. In recent years, advances in optical coherence tomography technology have improved our ability to image and measure the choroid in the human eye. Read More

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http://dx.doi.org/10.1111/cxo.12862DOI Listing
May 2019
2 Reads

A successful 50-year history of anterior lamellar keratoplasty performed for keratoconus in New Zealand.

Clin Exp Optom 2018 Dec 19. Epub 2018 Dec 19.

Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1111/cxo.12866DOI Listing
December 2018
1 Read

An evidence-based approach to the routine use of optical coherence tomography.

Clin Exp Optom 2019 May 17;102(3):242-259. Epub 2018 Dec 17.

Centre for Eye Health, The University of New South Wales, Sydney, New South Wales, Australia.

Optical coherence tomography is an imaging technology that has revolutionised the detection, assessment and management of ocular disease. It is now a mainstream technology in clinical practice and is performed by non-specialised personnel in some settings. This article provides a clinical perspective on the implications of that movement and describes best practice using multimodal imaging and an evidence-based approach. Read More

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http://doi.wiley.com/10.1111/cxo.12847
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http://dx.doi.org/10.1111/cxo.12847DOI Listing
May 2019
10 Reads

Comparison of central corneal thickness measurements with standard ultrasonic pachymetry and optical devices.

Clin Exp Optom 2019 Mar 17;102(2):126-130. Epub 2018 Dec 17.

Department of Ophthalmology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

Background: To compare the repeatability and agreements of central corneal thickness measurements of healthy individuals obtained by Scheimpflug-Placido topographer (Sirius), anterior segment spectral domain optical coherence tomography (Spectralis) (AS-OCT), optical biometry (AL-Scan) and ultrasonic pachymetry.

Methods: Sixty-four eyes of 32 subjects with no ocular or systemic diseases were included in this study. Central corneal thickness measurements performed with Sirius, AS-OCT, optical biometry AL-Scan and ultrasonic pachymetry were compared. Read More

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http://dx.doi.org/10.1111/cxo.12865DOI Listing
March 2019
4 Reads

Intraocular pressure changes in eyes with small incision lenticules and laser in situ keratomileusis.

Clin Exp Optom 2018 Dec 17. Epub 2018 Dec 17.

Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.

Background: Measuring intraocular pressure after refractive surgery is a challenge in the diagnosis, evaluation, and treatment of glaucoma. Intraocular pressure characteristics after laser in situ keratomileusis (LASIK) are well known. However, intraocular pressure measurement and characteristics after small incision lenticule extraction (SMILE) are still unknown, providing an interesting point of comparison in terms of biomechanical differences from LASIK. Read More

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http://dx.doi.org/10.1111/cxo.12861DOI Listing
December 2018
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Debunking a myopic view of nature versus nurture.

Authors:
John L Hopper

Clin Exp Optom 2019 Jan;102(1):1-2

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Carlton, Victoria, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cxo.12850
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http://dx.doi.org/10.1111/cxo.12850DOI Listing
January 2019
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Optical coherence tomography in the investigation of systemic neurologic disease.

Clin Exp Optom 2019 May 11;102(3):309-319. Epub 2018 Dec 11.

Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.

Optical coherence tomography (OCT) is a well-established technique for the clinical examination, diagnosis, severity staging and monitoring of ophthalmic disorders. The application of this technology has more recently been extended beyond ophthalmic disease, whereby it has been demonstrated that OCT can serve as an ophthalmic marker for a range of systemic neurodegenerative disorders, such as Parkinson's disease, multiple sclerosis, Alzheimer's disease and diabetic peripheral neuropathy. This review will focus on the clinical utility of OCT-derived retinal measures for the investigation of these conditions. Read More

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http://dx.doi.org/10.1111/cxo.12858DOI Listing
May 2019
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Low-dose brimonidine for relief of ocular redness: integrated analysis of four clinical trials.

Clin Exp Optom 2019 Mar 7;102(2):131-139. Epub 2018 Dec 7.

Clinical Affairs, Bausch + Lomb, Bridgewater, New Jersey, USA.

Background: The aim of this study was to provide an integrated analysis of safety and efficacy data for brimonidine tartrate ophthalmic solution 0.025 per cent (low-dose; Bausch & Lomb Incorporated), a topical vasoconstrictor for relief of ocular redness.

Methods: Integrated efficacy data from two randomised, double-masked, vehicle-controlled studies in subjects with ocular redness as well as safety data from the two efficacy studies, a vehicle-controlled safety study, and a pharmacokinetic study were analysed. Read More

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http://dx.doi.org/10.1111/cxo.12846DOI Listing
March 2019
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