- Naomi Tsurikisawa,
- Chiyako Oshikata,
- Maiko Watanabe,
- Takahiro Tsuburai,
- Takeshi Kaneko,
- Hiroshi Saito
Clin Exp Allergy 2018 Jun 16. Epub 2018 Jun 16.
Clinical Research Center, National Hospital Organization Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku Sagamihara, Kanagawa, Japan, 252-0392.
Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a disease characterized by allergic granulomatosis, necrotizing vasculitis, and peripheral blood eosinophilia. Interleukin (IL)-33, thymic stromal lymphopoietin (TSLP), and type-2 innate lymphoid cells (ILC2) are involved in the innate and type-2 immune responses in EGPA. However, the relationships among these molecules and the mechanisms underlying the development of EGPA remain unknown. Read More