458 results match your criteria Clinical Utility of Evoked Potentials


Clinical utility of cervical vestibular-evoked myogenic potentials in predicting residual dizziness after benign paroxysmal positional vertigo.

Clin Neurophysiol 2018 Nov 22;130(1):95-100. Epub 2018 Nov 22.

Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objectives: In the present study, the value of cervical vestibular-evoked myogenic potential (cVEMP) as a predictive factor for residual dizziness after recovery of benign paroxysmal positional vertigo (BPPV) was evaluated.

Methods: The present study included 65 patients who had BPPV and underwent cVEMP testing. Patients were divided into two groups depending on the presence or absence of residual dizziness after recovery of BPPV. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2018.11.005DOI Listing
November 2018
1 Read

Clinical utility of contact heat evoked potentials (CHEPs) in a case of mentalis nerve lesion.

Clin Neurophysiol Pract 2018 7;3:74-77. Epub 2018 Apr 7.

EMG and Motor Control Unit, Hospital Clínic, University of Barcelona, Barcelona, Spain.

Objective: Nociceptive evoked potentials are still infrequently used in electrodiagnostic studies of single patients. We report a case in which the results of contact heat evoked potentials (CHEPs) provided unique information for the diagnosis.

Methods: After biopsy for a local cementoma, a 21-year-old woman presented with neuropathic pain in the distribution of her left mentalis nerve. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S2467981X183001
Publisher Site
http://dx.doi.org/10.1016/j.cnp.2018.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133906PMC
April 2018
1 Read

Evidence of neurophysiological improvement of early manifestations of small-fiber dysfunction after liver transplantation in a patient with familial amyloid neuropathy.

Clin Neurophysiol Pract 2018 17;3:40-44. Epub 2018 Feb 17.

EMG and Motor Control Section, Neurology Department, Hospital Clinic, University of Barcelona, Barcelona, Spain.

Introduction: Small fiber polyneuropathy (SFP) is a common heralding clinical manifestation of damage to the nervous system in patients with familial amyloidosis. The diagnosis of SFP is a significant factor in the decision to treat a previously asymptomatic gene carrier, as treatment would prevent irreversible nerve damage. This requires detection of the earliest but unequivocal signs of peripheral nerve involvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cnp.2018.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133776PMC
February 2018

Visual Evoked Potentials as a Biomarker in Multiple Sclerosis and Associated Optic Neuritis.

J Neuroophthalmol 2018 Sep;38(3):350-357

Department of Neurology, Institute of Experimental Neurology-INSPE, San Raffaele University Hospital, Milan, Italy.

: ABSTRACT:: Multiple sclerosis (MS) is an inflammatory, degenerative disease of the central nervous system (CNS) characterized by progressive neurological decline over time. The need for better "biomarkers" to more precisely capture and track the effects of demyelination, remyelination, and associated neuroaxonal injury is a well-recognized challenge in the field of MS. To this end, visual evoked potentials (VEPs) have a role in assessing the extent of demyelination along the optic nerve, as a functionally eloquent CNS region. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WNO.0000000000000704DOI Listing
September 2018
7 Reads

Effect of attention bias modification on event-related potentials in patients with irritable bowel syndrome: A preliminary brain function and psycho-behavioral study.

Neurogastroenterol Motil 2018 Oct 30;30(10):e13402. Epub 2018 Jul 30.

Center for Health and Community Medicine, Nagasaki University, Nagasaki, Japan.

Background: Attention bias modification normalizes electroencephalographic abnormalities in alpha and beta power percentages related to attention in patients with irritable bowel syndrome (IBS). Yet, it is unknown whether ABM contributes to the normalization of event-related potentials (ERP) in these patients. We hypothesized that ERP related to attention deficit would be normalized after ABM implementation in individuals with IBS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nmo.13402DOI Listing
October 2018

Somatosensory Evoked Potentials as a Tool to Evaluate Brainstem Herniation in the Neuroscience Intensive Care Unit.

Cureus 2018 Apr 6;10(4):e2443. Epub 2018 Apr 6.

Neurology, Texas Tech University Health Sciences Center Paul L Foster School of Medicine.

Somatosensory evoked potentials (SSEPs) are a sensitive, minimally invasive technique used to localize dysfunction of myelinated peripheral and central axons in the nervous system. The utility of SSEPs in acutely assessing central nervous system function in brainstem herniation in the neuroscience intensive care unit (NICU) has not been well established. We discuss a case of an 18-year-old, postpartum female who presented with intermittent headache, diplopia, nausea/vomiting and cachexia following delivery two months prior. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.2443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990027PMC
April 2018
5 Reads

[Clinical utility of evoked potentials in the field of addiction medicine].

Rev Med Suisse 2018 Jun;14(610):1189-1192

Secteur de psychiatrie et de psychothérapie de l'adulte, Réseau fribourgeois de santé mentale, Rue de l'Hôpital 140, 1633 Marsens.

Cognitive impairment is a frequent consequence of chronic and excessive alcohol consumption with impact on the daily lives of the concerned persons. Recovery during abstinence phases is often only partial. Improvement of cognitive functions has often a positive and lasting effect on the quality of live and the clinical symptoms of the patients suffering from an alcohol use disorder. Read More

View Article

Download full-text PDF

Source
June 2018
10 Reads

Response properties of the human frequency-following response (FFR) to speech and non-speech sounds: level dependence, adaptation and phase-locking limits.

Int J Audiol 2018 Sep 15;57(9):665-672. Epub 2018 May 15.

b School of Communication Sciences & Disorders , University of Memphis , Memphis , TN , USA.

Objective: The frequency-following response (FFR) is a neurophonic potential used to assess auditory neural encoding at subcortical stages. Despite the FFR's empirical and clinical utility, basic response properties of this evoked potential remain undefined.

Design: We measured FFRs to speech and nonspeech (pure tone, chirp sweeps) stimuli to quantify three key properties of this potential: level-dependence (I/O functions), adaptation and the upper limit of neural phase-locking. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14992027.2018.1470338DOI Listing
September 2018
4 Reads

Safeness and Utility of Concomitant Intraoperative Monitoring with Intraoperative Magnetic Resonance Imaging in Children: A Pilot Study.

World Neurosurg 2018 Jul 27;115:e637-e644. Epub 2018 Apr 27.

Clinical Neuroscience Center, Department of Neurosurgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Background: High-field intraoperative magnetic resonance imaging (MRI) has become increasingly available in neurosurgery centers. There is little experience with combined intraoperative MRI and intraoperative neurophysiologic monitoring (IONM). We report the first series, to our knowledge, of pediatric patients undergoing brain tumor surgery with 3T intraoperative MRI and IONM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.04.123DOI Listing

Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice.

Cerebellum 2018 Oct;17(5):628-653

Department of Neurology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany.

The purpose of this consensus paper is to review electrophysiological abnormalities and to provide a guideline of neurophysiological assessments in cerebellar ataxias. All authors agree that standard electrophysiological methods should be systematically applied in all cases of ataxia to reveal accompanying peripheral neuropathy, the involvement of the dorsal columns, pyramidal tracts and the brainstem. Electroencephalography should also be considered, although findings are frequently non-specific. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12311-018-0937-2DOI Listing
October 2018
2 Reads

Auditory Mismatch Negativity and P300a Elicited by the "Optimal" Multi-feature Paradigm in Early Schizophrenia.

Clin EEG Neurosci 2018 Jul 4;49(4):238-247. Epub 2018 Mar 4.

2 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.

The mismatch negativity (MMN) is an EEG-derived event-related potential (ERP) elicited by any violation of a predicted auditory "rule," regardless of whether one is attending to the stimuli and is thought to reflect updating of the stimulus context. Redirection of attention toward a rare, distracting stimulus event, however, can be measured by the subsequent P3a component of the P300. Chronic schizophrenia patients exhibit robust MMN deficits, as well as reductions in P3a amplitude. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1550059418761459DOI Listing
July 2018
6 Reads

Test-Retest Reliability of Dual-Recorded Brainstem versus Cortical Auditory-Evoked Potentials to Speech.

J Am Acad Audiol 2018 Feb;29(2):164-174

School of Communication Sciences and Disorders, University of Memphis, Memphis, TN.

Background: Auditory-evoked potentials have proven useful in the objective evaluation of sound encoding at different stages of the auditory pathway (brainstem and cortex). Yet, their utility for use in clinical assessment and empirical research relies critically on the precision and test-retest repeatability of the measure.

Purpose: To determine how subcortical/cortical classes of auditory neural responses directly compare in terms of their internal consistency and test-retest reliability within and between listeners. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3766/jaaa.16167DOI Listing
February 2018
4 Reads

Neurophysiology of the pelvic floor in clinical practice: a systematic literature review.

Funct Neurol 2017 Oct/Dec;22(4):173-193

Neurophysiological testing of the pelvic floor is recognized as an essential tool to identify pathophysiological mechanisms of pelvic floor disorders, support clinical diagnosis, and aid in therapeutic decisions. Nevertheless, the diagnostic value of these tests in specific neurological diseases of the pelvic floor is not completely clarified. Seeking to fill this gap, the members of the Neurophysiology of the Pelvic Floor Study Group of the Italian Clinical Neurophysiology Society performed a systematic review of the literature to gather available evidence for and against the utility of neurophysiological tests. Read More

View Article

Download full-text PDF

Source
August 2018
6 Reads

Electrophysiology of Olfactory and Optic Nerve in Outpatient and Intraoperative Settings.

J Clin Neurophysiol 2018 Jan;35(1):3-10

Departments of Neurological Surgery and.

Evoked potentials are time-locked electrophysiologic potentials recorded in response to standardized stimuli using scalp electrodes. These responses provide good temporal resolution and have been used in various clinical and intraoperative settings. Olfactory evoked potentials (OEPs) may be used as an adjunct tool in identifying patients of Parkinson disease and Alzheimer dementia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WNP.0000000000000416DOI Listing
January 2018
3 Reads

Electrophysiology of Extraocular Cranial Nerves: Oculomotor, Trochlear, and Abducens Nerve.

J Clin Neurophysiol 2018 Jan;35(1):11-15

Departments of Neurological Surgery and.

The utility of extraocular cranial nerve electrophysiologic recordings lies primarily in the operating room during skull base surgeries. Surgical manipulation during skull base surgeries poses a risk of injury to multiple cranial nerves, including those innervating extraocular muscles. Because tumors distort normal anatomic relationships, it becomes particularly challenging to identify cranial nerve structures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WNP.0000000000000417DOI Listing
January 2018
8 Reads

Clinical Utility of Intraoperative Motor-Evoked Potential Monitoring to Prevent Postoperative Spinal Cord Injury in Thoracic and Thoracoabdominal Aneurysm Repair: An Audit of the Japanese Association of Spinal Cord Protection in Aortic Surgery Database.

Anesth Analg 2018 03;126(3):763-768

From the Department of Anesthesiology, National Cerebral and Cardiovascular Center, Suita, Japan.

Background: Spinal cord ischemic injury is the most devastating sequela of descending and thoracoabdominal aortic surgery. Motor-evoked potentials (MEPs) have been used to intraoperatively assess motor tract function, but it remains unclear whether MEP monitoring can decrease the incidence of postoperative motor deficits. Therefore, we reviewed multicenter medical records of patients who had undergone descending and thoracoabdominal aortic repair (both open surgery and endovascular repair) to assess the association of MEP monitoring with postoperative motor deficits. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00000539-201803000-0001
Publisher Site
http://dx.doi.org/10.1213/ANE.0000000000002749DOI Listing
March 2018
16 Reads

Altered Neurocognitive Processing of Tactile Stimuli in Patients with Complex Regional Pain Syndrome.

J Pain 2018 Apr 8;19(4):395-409. Epub 2017 Dec 8.

Department of Psychological Sciences, Faculty of Psychology, Health and Society, University of Liverpool, Liverpool, United Kingdom; CamPAIN Group, Department of Anaesthesia, University of Cambridge, Cambridge, United Kingdom. Electronic address:

Chronic pain in complex regional pain syndrome (CRPS) has been linked to tactile misperceptions and deficits in somatotopic representation of the affected limb. In this study, we identify altered cognitive processing of tactile stimuli in CRPS patients that we propose marks heterogeneity in tactile decision-making mechanisms. In a case-control design, we compared middle- and late-latency somatosensory evoked potentials in response to pseudorandomized mechanical stimulation of the digits of both hands (including CRPS-affected and nonaffected sides) between 13 CRPS patients and 13 matched healthy controls. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpain.2017.11.008DOI Listing
April 2018
8 Reads

Word Processing in Children With Autism Spectrum Disorders: Evidence From Event-Related Potentials.

J Speech Lang Hear Res 2017 Dec;60(12):3441-3455

Vanderbilt Kennedy Center for Research on Human Development and Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.

Purpose: This investigation was conducted to determine whether young children with autism spectrum disorders exhibited a canonical neural response to word stimuli and whether putative event-related potential (ERP) measures of word processing were correlated with a concurrent measure of receptive language. Additional exploratory analyses were used to examine whether the magnitude of the association between ERP measures of word processing and receptive language varied as a function of the number of word stimuli the participants reportedly understood.

Method: Auditory ERPs were recorded in response to spoken words and nonwords presented with equal probability in 34 children aged 2-5 years with a diagnosis of autism spectrum disorder who were in the early stages of language acquisition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1044/2017_JSLHR-S-17-0011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111525PMC
December 2017
7 Reads

Motor cortex excitability in seizure-free STX1B mutation carriers with a history of epilepsy and febrile seizures.

Clin Neurophysiol 2017 12 20;128(12):2503-2509. Epub 2017 Oct 20.

Department of Neurology & Stroke, and Hertie Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany. Electronic address:

Objective: Mutations in STX1B encoding the presynaptic protein syntaxin-1B are associated with febrile seizures with or without epilepsy. It is unclear to what extent these mutations are linked to abnormalities of cortical glutamatergic or GABAergic neurotransmission. We explored this question using single- and paired-pulse transcranial magnetic stimulation (TMS) excitability markers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2017.10.008DOI Listing
December 2017
9 Reads

Practice guideline: Cervical and ocular vestibular evoked myogenic potential testing: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Neurology 2017 Nov 1;89(22):2288-2296. Epub 2017 Nov 1.

From the Department of Neurology (T.D.F.), Barrow Neurological Institute and University of Arizona College of Medicine, Phoenix; Department of Neurology (J.G.C.), Prince of Wales Hospital, Clinical School, University of New South Wales and Neuroscience Research Australia, Randwick, Sydney; Departments of Neurology (K.A.K., B.C.) and Neurosurgery (J.F.), University of Michigan, Ann Arbor; Department of Audiology and Neurotology (K.B.), Karolinska University Hospital, Stockholm, Sweden; Department of Neurology and German Center for Dizziness and Balance Disorders (M.S.), University of Munich, Germany; Department of Neurology (H.L.), Keimyung University School of Medicine, Daegu, South Korea; Department of Neurology (M.F.W.), Case Western Reserve University, and Louis Stokes Cleveland Veterans Affairs Medical Center, OH; Bronson Neuroscience Center (E.A.), Kalamazoo, MI; and Department of Neurology (D.S.G.), Charleston Area Medical Center, WV.

Objective: To systematically review the evidence and make recommendations with regard to diagnostic utility of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP, respectively). Four questions were asked: Does cVEMP accurately identify superior canal dehiscence syndrome (SCDS)? Does oVEMP accurately identify SCDS? For suspected vestibular symptoms, does cVEMP/oVEMP accurately identify vestibular dysfunction related to the saccule/utricle? For vestibular symptoms, does cVEMP/oVEMP accurately and substantively aid diagnosis of any specific vestibular disorder besides SCDS?

Methods: The guideline panel identified and classified relevant published studies (January 1980-December 2016) according to the 2004 American Academy of Neurology process.

Results And Recommendations: Level C positive: Clinicians may use cVEMP stimulus threshold values to distinguish SCDS from controls (2 Class III studies) (sensitivity 86%-91%, specificity 90%-96%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000004690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705249PMC
November 2017
19 Reads

A novel low-cost approach for navigated transcranial magnetic stimulation.

Restor Neurol Neurosci 2017 ;35(6):601-609

Department of Physical Medicine and Rehabilitation, University of Michigan Medical School, Ann Arbor, MI, USA.

Background: Transcranial magnetic stimulation (TMS) is commonly used for assessing or modulating brain excitability. However, the credibility of TMS outcomes depends on accurate and reliable coil placement during stimulation. Navigated TMS systems can address this issue, but these systems are expensive for routine use in clinical and research environments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/RNN-170751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738908PMC
July 2018
3 Reads

EEG and ERP biomarkers of Alzheimer's disease: a critical review.

Front Biosci (Landmark Ed) 2018 Jan 1;23:183-220. Epub 2018 Jan 1.

National Institute of Clinical Neurosciences, 57 Amerikai ut, Budapest, 1145, Hungary.

Here we critically review studies that used electroencephalography (EEG) or event-related potential (ERP) indices as a biomarker of Alzheimer's disease. In the first part we overview studies that relied on visual inspection of EEG traces and spectral characteristics of EEG. Second, we survey analysis methods motivated by dynamical systems theory (DST) as well as more recent network connectivity approaches. Read More

View Article

Download full-text PDF

Source
January 2018
13 Reads

Post-tetanic transcranial motor evoked potentials augment the amplitude of compound muscle action potentials recorded from innervated and non-innervated muscles.

Spine J 2018 05 1;18(5):740-746. Epub 2017 Sep 1.

Department of Orthopaedic Surgery, Nara Medical University, 840 Shijo-cho, Kashihara City, Nara 6348522, Japan.

Background Context: Transcranial electrical stimulation used to produce motor evoked potentials (TES-MEPs) and subsequent compound muscle action potential (CMAP) recording is widely used to monitor motor function during surgery when there is risk of damaging the spinal cord. Nonetheless, some muscles do not produce CMAP amplitudes sufficient for intraoperative monitoring.

Purpose: This study aimed to investigate the utility of tetanic stimulation at single and multiple peripheral nerve sites for augmenting CMAP amplitudes recorded from innervated and non-innervated muscles. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15299430173096
Publisher Site
http://dx.doi.org/10.1016/j.spinee.2017.08.249DOI Listing
May 2018
10 Reads

The Clinical Utility of Vestibular-Evoked Myogenic Potentials in the Diagnosis of Ménière's Disease.

Front Neurol 2017 15;8:415. Epub 2017 Aug 15.

School of Speech Language Pathology and Audiology, Université de Montréal, Montreal, QC, Canada.

Ménière's disease (MD) is a condition that has been proposed over 150 years ago, which involves audiological and vestibular manifestations, such as aural fullness, tinnitus, vertigo, and fluctuating hearing thresholds. Over the past few years, many researchers have assessed different techniques to help diagnose this pathology. Vestibular-evoked myogenic potential (VEMP) is an electrophysiological method assessing the saccule (cVEMP) and the utricule (oVEMP). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2017.00415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559476PMC
August 2017
5 Reads

Comparison of visual evoked potential monitoring during spine surgeries under total intravenous anesthesia versus balanced general anesthesia.

Clin Neurophysiol 2017 10 9;128(10):2006-2013. Epub 2017 Aug 9.

The Ohio State University Wexner Medical Center, Department of Anesthesiology, Columbus, OH, USA; The Ohio State University Wexner Medical Center, Department of Neurological Surgery, Columbus, OH, USA.

Objective: To determine the comparison of its clinical utility and safety profile for visual evoked potential (VEP) monitoring during prone spine surgeries under total intravenous anesthesia (TIVA) versus balanced general anesthesia using the SightSaver™ visual stimulator.

Methods: The protocol was designed asa pilot, single center, prospective, randomized, and double-arm study. Subjects were randomized to receive either TIVA or balanced general anesthesia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2017.07.420DOI Listing
October 2017
11 Reads

Emotion regulation in adolescents: An ERP study.

Biol Psychol 2017 10 10;129:52-61. Epub 2017 Aug 10.

Research Department of Clinical, Educational and Health Psychology, University College London & The Anna Freud National Centre for Children and Families, London, United Kingdom.

Aims: The use of emotion regulation strategies can reduce the intensity of negative emotional experiences. Event related potentials (ERPs), specifically the late positive potential (LPP), are known to be sensitive to this modulation in adults. This is the first study to explore the neural correlates of expressive suppression in adolescents. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopsycho.2017.08.001DOI Listing
October 2017
13 Reads

Auditory brainstem response (ABR) profiling tests as diagnostic support for schizophrenia and adult attention-deficit hyperactivity disorder (ADHD).

Acta Neuropsychiatr 2018 Jun 14;30(3):137-147. Epub 2017 Aug 14.

Department of Neuroscience, Psychiatry,Uppsala University,Uppsala University Hospital,Uppsala,Sweden.

Objective: To evaluate the performances of two auditory brainstem response (ABR) profiling tests as potential biomarkers and diagnostic support for schizophrenia and adult attention-deficit hyperactivity disorder (ADHD), respectively, in an investigator-initiated blinded study design.

Method: Male and female patients with schizophrenia (n=26) and adult ADHD (n=24) meeting Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM IV) diagnostic criteria and healthy controls (n=58) comprised the analysis set (n=108) of the total number of study participants (n=119). Coded sets of randomized ABR recordings were analysed by an independent party blinded to clinical diagnoses before a joint code-breaking session. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/neu.2017.24DOI Listing
June 2018
25 Reads

Ethambutol optic neuropathy.

Curr Opin Ophthalmol 2017 Nov;28(6):545-551

aBaylor College of Medicine bDepartment of Ophthalmology, Blanton Eye Institute, Houston Methodist Hospital cDepartments of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medicine dDepartment of Ophthalmology, UTMB, Galveston, University of Iowa Hospitals and Clinics, Texas A and M College of Medicine eUniversity of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

Purpose Of Review: We provide a summary of the epidemiology, clinical findings, management and outcomes of ethambutol-induced optic neuropathy (EON). Ethambutol-induced optic neuropathy is a well-known, potentially irreversible, blinding but largely preventable disease. Clinicians should be aware of the importance of patient and physician education as well as timely and appropriate screening. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICU.0000000000000416DOI Listing
November 2017
9 Reads

Warning criteria for intraoperative neurophysiologic monitoring.

Curr Opin Anaesthesiol 2017 Oct;30(5):557-562

aDepartment of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region bShandong Provincial Hospital cDepartment of Neurology, Qilu Hospital, Shandong University dBinzhou People's Hospital, Shandong eDepartment of Anaesthesia and Intensive Care, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences fDepartment of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.

Purpose Of Review: Intraoperative changes in somatosensory (SEP) and motor evoked potentials (MEPs) may indicate potential injury to the spinal cord and will require timely intervention to prevent permanent damage. This review focuses on the validity of currently recommended warning criteria for intraoperative evoked potential monitoring.

Recent Findings: Current guideline recommends a decrease in SEP amplitude by 50% and MEP amplitude by 50-100% as warning signals for injury to the ascending sensory and descending motor pathway, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ACO.0000000000000505DOI Listing
October 2017
24 Reads

Brainstem Auditory Evoked Potentials for diagnosing Autism Spectrum Disorder, ADHD and Schizophrenia Spectrum Disorders in adults. A blinded study.

Psychiatry Res 2017 11 6;257:21-26. Epub 2017 Jul 6.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; School of Medical Sciences, Örebro University, Örebro, SE-70182 Örebro, Sweden; University Health Care Research Centre, Örebro University, Örebro, Sweden. Electronic address:

The aim of the present study was to examine the clinical utility of complex auditory brainstem response (c-ABR) and investigate if c-ABR is helpful in the diagnostic procedure. Thirty-one adult psychiatric patients, thoroughly diagnosed with autism spectrum disorder (ASD) (n=16), ADHD (n=8), or schizophrenia spectrum disorder (SSD) (n=7) and 15 healthy controls (HC), were blindly assessed with SensoDetect BERA. This c-ABR correctly identified psychiatric diagnoses in 4 patients (13%) and provided partially correct diagnoses in 11 more patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psychres.2017.06.085DOI Listing
November 2017
10 Reads

Utility of somatosensory evoked potentials in the assessment of response to IVIG in a long-lasting case of chronic immune sensory polyradiculopathy.

BMC Neurol 2017 Jul 1;17(1):127. Epub 2017 Jul 1.

Neurology Unit, Circolo & Macchi Foundation Hospital - Insubria University - DBSV, Viale L. Borri 57, 21100, Varese, Italy.

Background: Chronic immune sensory polyradiculopathy (CISP) identifies a progressive acquired peripheral dysimmune neuropathy recognized as a chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) variant. We describe a young woman with a thirteen-year history of CISP with a belated variable response to intravenous immunoglobulin (IVIG) and an almost erratic anticipation of symptoms between IVIG cycles. The association of IVIG and corticosteroids, immunosuppressants, plasmapheresis, did not lead to clinical improvement and was characterized by significant side effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12883-017-0906-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494125PMC
July 2017
16 Reads

Utility of Intraoperative Monitoring in the Resection of Spinal Cord Tumors: An Analysis by Tumor Location and Anatomical Region.

Spine (Phila Pa 1976) 2018 02;43(4):287-294

Department of Neurosurgery, University of Cincinnati, Cincinnati, OH.

Study Design: Retrospective review of institutional data.

Objective: The aim of this study was to assess the utility of somatosensory-evoked potentials (SSEP) and transcranial electric motor-evoked potentials (MEP) in the resection of spine tumors and evaluate the ability of both single and multi-modal monitoring to predict postoperative neurological deficits.

Summary Of Background Data: Although the utility of intraoperative monitoring (IOM) is well established in scoliosis and degenerative surgery, studies in spine tumor patients have been limited. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00007632-900000000-9547
Publisher Site
http://dx.doi.org/10.1097/BRS.0000000000002300DOI Listing
February 2018
19 Reads
1 Citation
2.300 Impact Factor

Relationship Between Motor Evoked Potential Response and the Severity of Paralysis in Spinal Cord Injury Patients.

Ann Rehabil Med 2017 Apr 27;41(2):211-217. Epub 2017 Apr 27.

Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Objective: To investigate the relationship between motor evoked potential (MEP) response and the severity of motor paralysis, evaluated according to the Korean disability evaluation system in patients with spinal cord injury (SCI).

Methods: We analyzed 192 lower limbs of 96 SCI patients. Lower limbs were classified according to their motor scores, as determined by the International Standards for Neurological Classification of Spinal Cord Injury: motor score <10 (group 1); ≥10 and <15 (group 2); ≥15 and <20 (group 3); and ≥20 (group 4). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5535/arm.2017.41.2.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426257PMC
April 2017
6 Reads

Predictors and brain connectivity changes associated with arm motor function improvement from intensive practice in chronic stroke.

F1000Res 2016 31;5:2119. Epub 2016 Aug 31.

Providence VA Medical Center and VA Research and Development Center of Excellence, Center for Restorative and Regenerative Medicine, Brown University, Providence, RI, 02908, USA.

The brain changes that underlie therapy-induced improvement in motor function after stroke remain obscure. This study sought to demonstrate the feasibility and utility of measuring motor system physiology in a clinical trial of intensive upper extremity rehabilitation in chronic stroke-related hemiparesis. This was a substudy of two multi-center clinical trials of intensive robotic and intensive conventional therapy arm therapy in chronic, significantly hemiparetic, stroke patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/f1000research.8603.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345776PMC
August 2016
13 Reads

Functional Brain Activation in Response to a Clinical Vestibular Test Correlates with Balance.

Front Syst Neurosci 2017 10;11:11. Epub 2017 Mar 10.

School of Kinesiology, University of MichiganAnn Arbor, MI, USA; Department of Psychology, University of MichiganAnn Arbor, MI, USA.

The current study characterizes brain fMRI activation in response to two modes of vestibular stimulation: Skull tap and auditory tone burst. The auditory tone burst has been used in previous studies to elicit either a vestibulo-spinal reflex [saccular-mediated colic Vestibular Evoked Myogenic Potentials (cVEMP)], or an ocular muscle response [utricle-mediated ocular VEMP (oVEMP)]. Research suggests that the skull tap elicits both saccular and utricle-mediated VEMPs, while being faster and less irritating for subjects than the high decibel tones required to elicit VEMPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnsys.2017.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344901PMC
March 2017
6 Reads

Modulating motor cortical neuroplasticity with priming paired associative stimulation in young and old adults.

Clin Neurophysiol 2017 05 28;128(5):763-769. Epub 2017 Feb 28.

Discipline of Physiology, School of Medicine, The University of Adelaide, Adelaide, Australia. Electronic address:

Objective: To examine the effect of priming paired associative stimulation (PAS) on the modulation of motor cortex (M1) plasticity in young and old adults.

Methods: Fifteen young (20-27yrs) and 15 old (61-79yrs) subjects participated in 3 experimental sessions, with each session involving two consecutive PAS protocols separated by 10mins. The first (priming) protocol was either PAS (ISI=N20 latency+2ms), PAS (ISI=N20 latency-10ms), or PAS (ISI=100ms), whereas the second (test) protocol was always PAS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2017.02.011DOI Listing
May 2017
7 Reads

Delta and gamma oscillations in operculo-insular cortex underlie innocuous cold thermosensation.

J Neurophysiol 2017 05 1;117(5):1959-1968. Epub 2017 Mar 1.

Danish Pain Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Cold-sensitive and nociceptive neural pathways interact to shape the quality and intensity of thermal and pain perception. Yet the central processing of cold thermosensation in the human brain has not been extensively studied. Here, we used magnetoencephalography and EEG in healthy volunteers to investigate the time course (evoked fields and potentials) and oscillatory activity associated with the perception of cold temperature changes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/jn.00843.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411475PMC
May 2017
4 Reads
2.890 Impact Factor

Electrophysiological, cognitive and clinical profiles of at-risk mental state: The longitudinal Minds in Transition (MinT) study.

PLoS One 2017 10;12(2):e0171657. Epub 2017 Feb 10.

Centre for Brain and Mental Health Research, University of Newcastle, Newcastle, New South Wales, Australia.

The onset of schizophrenia is typically preceded by a prodromal period lasting several years during which sub-threshold symptoms may be identified retrospectively. Clinical interviews are currently used to identify individuals who have an ultra-high risk (UHR) of developing a psychotic illness with a view to provision of interventions that prevent, delay or reduce severity of future mental health issues. The utility of bio-markers as an adjunct in the identification of UHR individuals is not yet established. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302824PMC
August 2017
8 Reads

Splenius capitis is a reliable target for measuring cervical vestibular evoked myogenic potentials in adults.

Eur J Neurosci 2017 05 1;45(9):1212-1223. Epub 2017 Mar 1.

Department of Psychology, Brain and Mind Institute, University of Western Ontario, Toronto, ON, Canada.

The cervical vestibular evoked myogenic potential (cVEMP) is a common and simple test of vestibulospinal reflex patency. In the clinic, cVEMPs are measured in response to loud sounds from the sternocleidomastoid (SCM) on the ventral neck, as subjects maintain an uncomfortable head posture needed to recruit SCM. Here we characterize the cVEMP in a dorsal neck turner (splenius capitis; SPL), and compare it with the SCM cVEMP. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ejn.13536
Publisher Site
http://dx.doi.org/10.1111/ejn.13536DOI Listing
May 2017
4 Reads

Optogenetic Modulation of Urinary Bladder Contraction for Lower Urinary Tract Dysfunction.

Sci Rep 2017 01 18;7:40872. Epub 2017 Jan 18.

Center for Bionics, Korea Institute of Science and Technology (KIST), Seoul, 02792, Korea.

As current clinical approaches for lower urinary tract (LUT) dysfunction such as pharmacological and electrical stimulation treatments lack target specificity, thus resulting in suboptimal outcomes with various side effects, a better treatment modality with spatial and temporal target-specificity is necessary. In this study, we delivered optogenetic membrane proteins, such as channelrhodopsin-2 (ChR2) and halorhodopsin (NpHR), to bladder smooth muscle cells (SMCs) of mice using either the Cre-loxp transgenic system or a viral transfection method. The results showed that depolarizing ChR2-SMCs with blue light induced bladder contraction, whereas hyperpolarizing NpHR-SMCs with yellow light suppressed PGE-induced overactive contraction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep40872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241665PMC
January 2017
10 Reads

Motor-evoked potential gain is a helpful test for the detection of corticospinal tract dysfunction in amyotrophic lateral sclerosis.

Clin Neurophysiol 2017 Feb 23;128(2):357-364. Epub 2016 Dec 23.

Reference Center for Neuromuscular Disorders and ALS, CHU La Timone, 264 rue Saint Pierre, 13005 Marseille, France; Aix Marseille Univ, INSERM, GMGF, Marseille, France. Electronic address:

Objective: The detection of upper motor neuron (UMN) dysfunction is necessary for the diagnosis of amyotrophic lateral sclerosis (ALS). However, signs of UMN dysfunction may be difficult to establish. This study aimed to determine whether motor-evoked potential (MEP) gain (MEP area/background electromyographic activity) represents an efficient alternative to assess UMN dysfunction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2016.12.015DOI Listing
February 2017
3 Reads

Diagnostic utility of brain activity flow patterns analysis in attention deficit hyperactivity disorder.

Psychol Med 2017 May 9;47(7):1259-1270. Epub 2017 Jan 9.

SUNY Upstate Medical University,Syracuse,NY,USA.

Background: A previous small study suggested that Brain Network Activation (BNA), a novel ERP-based brain network analysis, may have diagnostic utility in attention deficit hyperactivity disorder (ADHD). In this study we examined the diagnostic capability of a new advanced version of the BNA methodology on a larger population of adults with and without ADHD.

Method: Subjects were unmedicated right-handed 18- to 55-year-old adults of both sexes with and without a DSM-IV diagnosis of ADHD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0033291716003329DOI Listing
May 2017
2 Reads

Desynchronization does not contribute to intracortical inhibition and facilitation: a paired-pulse paradigm study combined with TST.

J Neurophysiol 2017 03 14;117(3):1052-1056. Epub 2016 Dec 14.

Neurology Service, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland;

The paired-pulse (PP) transcranial magnetic stimulation (TMS) paradigms allow the exploration of the motor cortex physiology. The triple stimulation technique (TST) improves conventional TMS by reducing effects of desynchronization of motor neuron discharges allowing a precise evaluation of the corticospinal conduction. The objective of our study was to explore PP TMS paradigms combined with the TST to study whether the desynchronization contributes to these phenomena and whether the combined TMS-TST protocol could improve the consistency of responses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/jn.00381.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338616PMC
March 2017
7 Reads

Aberrant mTOR signaling and disrupted autophagy: The missing link in potential vigabatrin-associated ocular toxicity?

Clin Pharmacol Ther 2017 04 7;101(4):458-461. Epub 2017 Feb 7.

Division of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, Washington, USA.

Vigabatrin (VGB; γ-vinylGABA) is a unique antiepileptic directly elevating CNS GABA via inactivation of the GABA metabolic enzyme GABA-transaminase. VGB is effective in treating infantile spasms, a rare seizure disorder associated with significant morbidity. The potential for unexplained bilateral constriction of the visual field associated with VGB intervention can severely limit its temporal utility. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801739PMC
April 2017
7 Reads

Transcranial Magnetic Stimulation for the Assessment of Neurodegenerative Disease.

Neurotherapeutics 2017 01;14(1):91-106

Bushell Chair of Neurology, Brain and Mind Centre, University of Sydney, Camperdown, Australia.

Transcranial magnetic stimulation (TMS) is a noninvasive technique that has provided important information about cortical function across an array of neurodegenerative disorders, including Alzheimer's disease, frontotemporal dementia, Parkinson's disease, and related extrapyramidal disorders. Application of TMS techniques in neurodegenerative diseases has provided important pathophysiological insights, leading to the development of pathogenic and diagnostic biomarkers that could be used in the clinical setting and therapeutic trials. Abnormalities of TMS outcome measures heralding cortical hyperexcitability, as evidenced by a reduction of short-interval intracortical inhibition and increased in motor-evoked potential amplitude, have been consistently identified as early and intrinsic features of amyotrophic lateral sclerosis (ALS), preceding and correlating with the ensuing neurodegeneration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13311-016-0487-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233629PMC
January 2017
8 Reads

Cognitive impairments in patients with first episode psychosis: The relationship between neurophysiological and neuropsychological assessments.

J Clin Neurosci 2017 Feb 4;36:80-87. Epub 2016 Nov 4.

Department of Psychiatry, Hospital 12 de Octubre, Madrid, Spain; Department of Psychiatry, Complutense University of Madrid, Madrid, Spain.

Cognitive deficits in schizophrenia have been widely reported. Neurophysiological and neuropsychological assessments have been conducted to study these impairments. Event-related potentials (ERPs) are relevant markers of cognitive deficits in schizophrenia, and reductions in specific ERP components have been found. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jocn.2016.10.023DOI Listing
February 2017
12 Reads

Neural correlates of cognitive set shifting in amyotrophic lateral sclerosis.

Clin Neurophysiol 2016 Dec 13;127(12):3537-3545. Epub 2016 Oct 13.

Department of Neurology, Hannover Medical School, Hannover, Germany.

Objective: Amyotrophic lateral sclerosis (ALS) has been associated with executive dysfunction, particularly in the domain of cognitive set shifting. In a recent event-related potential (ERP) study, shifting-related cortical activity on a complex set-shifting paradigm was found to be attenuated in patients with ALS. Here, we investigated whether this ERP change could also be observed in a simplified set-shifting task adapted for potential clinical use, and in ALS patients without overt cognitive impairment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinph.2016.09.019DOI Listing
December 2016
7 Reads

Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity.

Redox Biol 2016 12 31;10:257-265. Epub 2016 Oct 31.

Department of Pharmaceutical Sciences, Southern Illinois University Edwardsville, Edwardsville, IL 62026, USA.

Cisplatin-induced ototoxicity remains a primary dose-limiting adverse effect of this highly effective anticancer drug. The clinical utility of cisplatin could be enhanced if the signaling pathways that regulate the toxic side-effects are delineated. In previous studies, we reported cisplatin-induced nitration of cochlear proteins and provided the first evidence for nitration and downregulation of cochlear LIM domain only 4 (LMO4) in cisplatin ototoxicity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redox.2016.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099269PMC
December 2016
18 Reads
1 Citation

mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice.

Pediatr Neurol 2017 01 3;66:44-52.e1. Epub 2016 Oct 3.

Division of Experimental and Systems Pharmacology, College of Pharmacy, Washington State University, Spokane, Washington. Electronic address:

Background: Gamma-vinyl-γ-aminobutyric acid (GABA) (vigabatrin) is an antiepileptic drug and irreversible GABA transaminase inhibitor associated with visual field impairment, which limits its clinical utility. We sought to relate altered visual evoked potentials associated with vigabatrin intake to transcriptional changes in the mechanistic target of rapamycin (mTOR) pathway and GABA receptors to expose further mechanisms of vigabatrin-induced visual field loss.

Methods: Vigabatrin was administered to mice via an osmotic pump for two weeks to increase GABA levels. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pediatrneurol.2016.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866057PMC
January 2017
7 Reads

TMSEEG: A MATLAB-Based Graphical User Interface for Processing Electrophysiological Signals during Transcranial Magnetic Stimulation.

Front Neural Circuits 2016 7;10:78. Epub 2016 Oct 7.

Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental HealthToronto, ON, Canada; Department of Psychiatry, University of TorontoToronto, ON, Canada.

Concurrent recording of electroencephalography (EEG) during transcranial magnetic stimulation (TMS) is an emerging and powerful tool for studying brain health and function. Despite a growing interest in adaptation of TMS-EEG across neuroscience disciplines, its widespread utility is limited by signal processing challenges. These challenges arise due to the nature of TMS and the sensitivity of EEG to artifacts that often mask TMS-evoked potentials (TEP)s. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncir.2016.00078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054290PMC
October 2017
14 Reads