11,722 results match your criteria Clinical Rheumatology[Journal]


Correction to: Proposal for a simple algorithm to differentiate adult-onset Still's disease with other fever of unknown origin causes: a longitudinal prospective study.

Clin Rheumatol 2019 Feb 19. Epub 2019 Feb 19.

Department of Internal Medicine, Division of Rheumatology, Hacettepe University Medical School, Sihhiye, 06100, Ankara, Turkey.

The author regrets that the original version of this article contained error. Figure 1 was shown in the wrong version, thus corrected figure is shown in this article. Read More

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http://dx.doi.org/10.1007/s10067-019-04479-4DOI Listing
February 2019

Efficacy of mycophenolate mofetil in Japanese patients with systemic lupus erythematosus.

Clin Rheumatol 2019 Feb 18. Epub 2019 Feb 18.

Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan.

Objectives: To assess the renal and non-renal efficacy of mycophenolate mofetil (MMF) in Japanese patients with systemic lupus erythematosus (SLE).

Methods: We conducted a retrospective study to assess the renal and non-renal efficacies of MMF in Japanese patients with systemic lupus erythematosus (SLE). We analyzed 14 patients with lupus nephritis (LN) who were given MMF, and 13 patients who received monthly intravenous cyclophosphamide (IVCY) as induction therapy, and a further 19 patients without LN who were treated with MMF, and 13 patients who took tacrolimus (TAC) to reduce glucocorticoid dosages. Read More

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http://dx.doi.org/10.1007/s10067-019-04473-wDOI Listing
February 2019

Efficacy of ω-3 supplementation in patients with psoriasis: a meta-analysis of randomized controlled trials.

Clin Rheumatol 2019 Feb 18. Epub 2019 Feb 18.

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.

Several studies have been conducted with the aim of investigating the effect of Omega(ω)-3 on different psoriasis indices including Psoriasis Area and Severity Index (PASI) score, erythema, scaling, itching, area involved, and infiltration. Nevertheless, a pooled analysis of trials that evaluated these variables has not been conducted. Therefore, the aim of this meta-analysis was to assess the efficacy of ω-3 fatty acids in treating patients with psoriasis. Read More

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http://dx.doi.org/10.1007/s10067-019-04456-xDOI Listing
February 2019

Hsp70 Gene Polymorphisms Are Associated With Disease Susceptibility and HRQOL Improvement in Chinese Han Population With Systemic Lupus Erythematosus.

J Clin Rheumatol 2019 Feb 13. Epub 2019 Feb 13.

Department of Biochemistry and Molecular Biology, School of Basic Medicine, Anhui Medical University, Hefei, Anhui, China.

Objectives: The aim of this study is to investigate whether heat shock protein 70 (Hsp70) gene polymorphisms are implicated in systemic lupus erythematous (SLE) susceptibility, the efficacy of glucocorticoids (GCs) treatment, and improvement of health-related quality of life.

Methods: A total of 499 SLE patients and 499 controls were included in a case-control study, and 468 SLE patients treated with GCs for 12 weeks were involved in a follow-up study. Patients who completed the 12-week follow-up were divided into GCs-sensitive and GCs-insensitive group by using the SLE disease activity index. Read More

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http://dx.doi.org/10.1097/RHU.0000000000000986DOI Listing
February 2019
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1.245 Impact Factor

Upregulated expression of STAT3/IL-17 in patients with systemic lupus erythematosus.

Clin Rheumatol 2019 Feb 15. Epub 2019 Feb 15.

Section of Rheumatology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.

Elevated IL-17 levels with higher Th17 numbers are identified in systemic lupus erythematosus (SLE). STAT3 signaling plays a crucial role in the Th17 generation, and SOCS3 negatively regulates their formation. We investigated IL-17, STAT3, and SOCS3 expression, and analyzed their correlations to elucidate the regulatory mechanisms of IL-17 production in SLE. Read More

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http://dx.doi.org/10.1007/s10067-019-04467-8DOI Listing
February 2019
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The immunogenicity of seasonal and pandemic influenza vaccination in autoimmune inflammatory rheumatic patients-a 6-month follow-up prospective study.

Clin Rheumatol 2019 Feb 14. Epub 2019 Feb 14.

Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, 1000, Slovenia.

Introduction: Influenza may cause severe complications in patients with autoimmune inflammatory rheumatic disease (AIRD), to whom vaccinations are especially recommended. However, AIRD patients require cautious scrutiny of immunogenicity as they might exhibit poor antibody response to vaccination, especially when taking immunomodulatory medications.

Aim: The aim was to determine immunogenicity of seasonal and pandemic influenza vaccine in AIRD patients, its timeline/persistence, and influence of medications on immune response. Read More

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http://dx.doi.org/10.1007/s10067-019-04439-yDOI Listing
February 2019

Venous vessel wall thickness in lower extremity is increased in male patients with Behcet's disease.

Clin Rheumatol 2019 Feb 13. Epub 2019 Feb 13.

Division of Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey.

Vascular involvement, especially in young males, is seen in up to 40% of the patients with Behcet's disease (BD) and is a major cause of mortality and morbidity. In this study, we investigated vessel wall thickness (VWT) and dilatation in lower extremity veins with Doppler ultrasound (US) in male BD patients. Sixty-one male patients with BD, 37 healthy male controls (HC) and 27 male patients, with ankylosing spondylitis (AS), were included in the study. Read More

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http://dx.doi.org/10.1007/s10067-019-04470-zDOI Listing
February 2019
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Reproductive rheumatology: the male perspective.

Clin Rheumatol 2019 Feb 13. Epub 2019 Feb 13.

Rheumatology Department, Northwick Park Hopsital, Harrow, London, UK.

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http://dx.doi.org/10.1007/s10067-019-04461-0DOI Listing
February 2019
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Subclinical synovitis and enthesitis in psoriasis patients and controls by ultrasonography in Saudi Arabia; incidence of psoriatic arthritis during two years.

Clin Rheumatol 2019 Feb 12. Epub 2019 Feb 12.

Department Psychology, Health and Technology, Faculty of Behavioral, Management and Social sciences, University of Twente, PO box 217, 7500 AE, Enschede, The Netherlands.

Objective: To evaluate ultrasonographic subclinical inflammatory synovitis and enthesitis in psoriasis patients, without clinical arthritis or enthesitis compared with healthy controls, with a 2-year follow-up to study the associated incidence of psoriatic arthritis (PsA).

Methods: A total of 109 consecutive psoriasis vulgaris patients without clinical signs of PsA and 90 healthy controls were included from two tertiary medical centers. Subjects underwent dermatological examination, PASI score evaluation for severity of psoriasis, musculoskeletal examination using 68/66 joints count for tenderness and swollen joints. Read More

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http://dx.doi.org/10.1007/s10067-019-04445-0DOI Listing
February 2019
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Effective serum level of etanercept biosimilar and effect of antidrug antibodies on drug levels and clinical efficacy in Chinese patients with ankylosing spondylitis.

Clin Rheumatol 2019 Feb 12. Epub 2019 Feb 12.

Department of Rheumatology and Immunology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun, 130033, China.

Objectives: To investigate the effective serum level of etanercept biosimilar in Chinese patients with ankylosing spondylitis (AS) who achieve AS Disease Activity Score-C-reactive protein (ASDAS-CRP) < 2.1, and the effect of antidrug antibodies on drug levels and clinical efficacy.

Methods: Our study enrolled 60 patients with AS who were treated with etanercept biosimilar. Read More

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http://link.springer.com/10.1007/s10067-018-04424-x
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http://dx.doi.org/10.1007/s10067-018-04424-xDOI Listing
February 2019
3 Reads

Macrophage migration inhibitory factor polymorphisms are a potential susceptibility marker in systemic sclerosis from southern Mexican population: association with MIF mRNA expression and cytokine profile.

Clin Rheumatol 2019 Feb 12. Epub 2019 Feb 12.

Instituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.

Introduction: Systemic sclerosis (SSc) is a complex autoimmune disease, characterized by microvascular lesions, autoimmunity, and fibrosis. It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases. The aim of this study was to analyze the relationship of the - 794 CATT and - 173G>C MIF polymorphisms with mRNA expression, MIF serum levels, and the Th1/Th2/Th17 cytokine profile in SSc. Read More

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http://dx.doi.org/10.1007/s10067-019-04459-8DOI Listing
February 2019

Clinical and MRI response to dose reduction of an etanercept-biosimilar for hip arthritis in patients with ankylosing spondylitis: an observational, retrospective cohort study.

Clin Rheumatol 2019 Feb 12. Epub 2019 Feb 12.

Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, No. 466 Xingangzhong Road, Guangzhou, 510317, China.

Objectives: Hip arthritis plays a critical role in the prognosis of ankylosing spondylitis (AS). Dose reduction of tumor necrosis factor inhibitors preserves general improvement of AS, so this study attempted to examine the equivalence between Yisaipu® tapering and conventional therapy for hip arthritis in AS patients, using clinical parameters and magnetic resonance image (MRI).

Methods: AS patients received this etanercept-biosimilar injections (50 mg/week) in the first 12 weeks. Read More

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http://link.springer.com/10.1007/s10067-019-04466-9
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http://dx.doi.org/10.1007/s10067-019-04466-9DOI Listing
February 2019
2 Reads

Utilize lung ultrasound B-lines and KL-6 to monitor anti-MDA-5 antibody-positive clinically amyopathic dermatomyositis-associated interstitial lung disease: a case report and literature review.

Clin Rheumatol 2019 Feb 11. Epub 2019 Feb 11.

Division of Rheumatology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.

In the past decade, lung ultrasound (LUS) B-lines and serum Krebs von den Lungen-6 (KL-6) antigen have been recognized as biomarkers of the connective tissue disease-associated interstitial lung diseases (CTD-ILDs). Robust data have demonstrated that B-lines total numbers and KL-6 levels are correlated with high-resolution computed tomography findings, pulmonary function test, and some clinical parameters in CTD-ILDs. However, limited data are available regarding the use of these two biomarkers to follow CTD-ILDs. Read More

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http://dx.doi.org/10.1007/s10067-019-04462-zDOI Listing
February 2019
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Incidence and prevalence of granulomatosis with polyangiitis and microscopic polyangiitis in health management organization in Argentina: a 15-year study.

Clin Rheumatol 2019 Feb 11. Epub 2019 Feb 11.

Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Perón 4190, 1414, Buenos Aires, Argentina.

Background/objective: Our objective was to estimate incidence and prevalence rates of granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) using data from a university hospital-based health management organization (HIMCO) in Latin America.

Methods: Multiple methods for case finding were used to ensure complete ascertainment. GPA was diagnosed if fulfilling ACR 1990 criteria or a clinical diagnosis was made by an experienced rheumatologist. Read More

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http://dx.doi.org/10.1007/s10067-019-04463-yDOI Listing
February 2019
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Serum YKL-40 level is associated with severity of interstitial lung disease and poor prognosis in dermatomyositis with anti-MDA5 antibody.

Clin Rheumatol 2019 Feb 9. Epub 2019 Feb 9.

Department of Medicine, Nanchang University, Nanchang, 330006, Jiangxi Province, China.

Objective: We aimed to investigate the clinical value of checking serum chitinase-3-like-1 protein (YKL-40) levels in anti-MDA5 antibody-positive dermatomyositis (anti-MDA5DM) patients.

Methods: One hundred and five consecutive anti-MDA5DM patients and 44 healthy controls were enrolled in this study. Baseline and follow-up serum YKL-40 were detected by ELISA. Read More

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http://dx.doi.org/10.1007/s10067-019-04457-wDOI Listing
February 2019
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Shedding light on vasculitis in Egypt: a multicenter retrospective cohort study of characteristics, management, and outcome.

Clin Rheumatol 2019 Feb 9. Epub 2019 Feb 9.

Rheumatology and Rehabilitation Department, Faculty of Medicine, Assiut University, Assiut, Egypt.

Objectives: The frequency of different vasculitides and their characteristics vary among different regions. The identification of geographic disparities of disease phenotypes helps the development of international criteria, allowing the classification of patients of different ethnicities. This study aimed to describe the frequency, characteristics, course, response to treatment, and outcome of the different adulthood vasculitides in Egypt. Read More

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http://dx.doi.org/10.1007/s10067-019-04441-4DOI Listing
February 2019
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Distinction between MPO-ANCA and PR3-ANCA-associated glomerulonephritis in Chinese patients: a retrospective single-center study.

Clin Rheumatol 2019 Feb 8. Epub 2019 Feb 8.

Jinling Clinical Medical College of Nanjing Medical University, Nanjing, China.

Objectives: To retrospectively investigate the clinical and histological features and outcomes of ANCA-associated glomerulonephritis (AAGN) with different ANCA serotypes.

Method: A total of 467 AAGN patients were divided into MPO-AAGN (MPO) and PR3-AAGN (PR3) groups according to ANCA serotype. Clinical and histological features and renal outcomes were compared. Read More

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http://dx.doi.org/10.1007/s10067-019-04458-9DOI Listing
February 2019
2 Reads

Evidence for M2 macrophage activation in patients with enthesitis-related arthritis category of juvenile idiopathic arthritis.

Clin Rheumatol 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, India.

Recently, an increase in CD163 macrophages in ileal biopsies from ankylosing spondylitis patients and an increase in intermediate monocytes in enthesitis-related arthritis (ERA) have been reported. Thus, we studied sCD163 levels as M2 macrophage marker in serum and synovial fluid (SF) of ERA children and CD163 expression on monocyte subsets. Serum samples from ERA patients and healthy controls (HC) were assayed for sCD163 (ELISA). Read More

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http://dx.doi.org/10.1007/s10067-018-04408-xDOI Listing
February 2019
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Chronic hepatitis B viral infection among RA patients-a cross-sectional control study.

Clin Rheumatol 2019 Feb 8. Epub 2019 Feb 8.

Department of Medicine 'B', Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, 52621, Tel-Hashomer, Israel.

Background And Objectives: Rheumatoid arthritis (RA) is the most common inflammatory joint disorder presenting also with extra-articular manifestations. As many other autoimmune diseases, it has been suggested that infectious diseases might contribute to its emergence. Hepatitis viruses were suggested by several reports as a trigger of RA onset. Read More

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http://link.springer.com/10.1007/s10067-019-04448-x
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http://dx.doi.org/10.1007/s10067-019-04448-xDOI Listing
February 2019
4 Reads

The clinical spectrum of Henoch-Schönlein purpura in children: a single-center study.

Clin Rheumatol 2019 Feb 8. Epub 2019 Feb 8.

Kanuni Sultan Süleyman Research and Training Hospital, Department of Pediatric Rheumatology, University of Health Science, No: 46/1, Kucukcekmece, 34303, Istanbul, Turkey.

Objectives: Henoch-Schönlein purpura (HSP) is the most common vasculitis of children. The aim of this study is to evaluate the demographic and clinic findings of patients with HSP and also to determine predictive factors for assessing the development of gastrointestinal system (GIS) and renal involvement.

Methods: This study was performed prospectively among children with HSP who are under 18 years of age and being followed-up in the Pediatric Rheumatology Unit of Health Sciences University Kanuni Sultan Süleyman Training and Research Hospital between January 2016 and January 2018. Read More

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http://dx.doi.org/10.1007/s10067-019-04460-1DOI Listing
February 2019

Effect of biologic disease-modifying anti-rheumatic drugs for patients with rheumatoid arthritis who hope to become mothers.

Clin Rheumatol 2019 Feb 7. Epub 2019 Feb 7.

Department of Internal Medicine, Division of Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.

Objectives: We examined the effect of biologic disease-modifying anti-rheumatic drugs on the time to pregnancy in patients with rheumatoid arthritis who hope to become mothers. Additionally, we evaluated adverse pregnancy outcomes and risk factors of these drugs.

Method: We retrospectively investigated 25 pregnancies of 19 patients who were taking disease-modifying anti-rheumatic drugs. Read More

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http://dx.doi.org/10.1007/s10067-019-04450-3DOI Listing
February 2019
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Exploring metabolic and inflammatory abnormalities in rheumatoid arthritis patients developing stroke disease: a case-control study using electronic medical record data in northern China.

Clin Rheumatol 2019 Feb 7. Epub 2019 Feb 7.

Department of Clinical Epidemiology and Evidence-based medicine, The First Affiliated Hospital of China Medical University, No.155, Nan Jing Bei Street, Shenyang, 110001, Liaoning Province, China.

Objectives: Intend to investigate the roles of serum lipids, inflammatory markers, and serological status in rheumatoid arthritis and stroke patients by using case-control study.

Materials And Methods: Clinical data were retrieved from the electronic medical record of the First Affiliated Hospital of China Medical University during January 2011 to March 2018. The obtained data were categorized into case groups and three control groups, in the ratios of 1:2, respectively, with all matching age and gender. Read More

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http://dx.doi.org/10.1007/s10067-019-04440-5DOI Listing
February 2019
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A Rare Case of IgG4-Related Disease Presenting as a Unilateral Severe Dacryoadenitis Complicated by Hypophysitis and Hypertrophic Pachymeningitis.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan Department of Ophthalmology and Visual Science, Hiroshima University Hospital, Hiroshima, Japan Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan Department of Endocrinology and Diabetic Medicine, Hiroshima University Hospital, Hiroshima, Japan Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.

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http://dx.doi.org/10.1097/RHU.0000000000000989DOI Listing
February 2019

Things Come in 3's… Or So It Seems.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

From the Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

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http://dx.doi.org/10.1097/RHU.0000000000000988DOI Listing
February 2019

Secondary Osteoarthropathy: An Unusual Cause of Polyarthralgia.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

From the Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1097/RHU.0000000000000972DOI Listing
February 2019
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Body Composition Is Associated With Physical Performance in Individuals With Knee Osteoarthritis.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Background/objective: The purpose of this cross-sectional study was to determine associations between body composition, self-reported function, and physical performance after accounting for body mass index (BMI) in individuals with knee osteoarthritis.

Methods: Percent fat and lean mass were evaluated using dual energy x-ray absorptiometry. Self-reported function (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC] function subscale) and physical performance (20-m walk, chair stand, and stair climb) were collected on 46 adults (30% male; BMI, 29. Read More

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http://dx.doi.org/10.1097/RHU.0000000000000967DOI Listing
February 2019

Treatment of Chronic Chikungunya With Methotrexate.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Division of Hospital Medicine, Department of Medicine, School of Medicine and Health Sciences, The George Washington University Division of Infectious Diseases, Department of Medicine, School of Medicine and Health Sciences, The George Washington University Division of General Internal Medicine, Department of Medicine, School of Medicine and Health Sciences, The George Washington University.

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http://dx.doi.org/10.1097/RHU.0000000000000998DOI Listing
February 2019

Outcomes of Pregnancy in Women With Inflammatory Myositis: A Retrospective Cohort From India.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

From the Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Objectives: Idiopathic inflammatory myositis (IIM) commonly affects women in the childbearing age group. Both disease activity and immunosuppressants used may have adverse effects on fertility and outcomes of pregnancy. We explored these outcomes in a retrospective cohort of women with IIM. Read More

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http://dx.doi.org/10.1097/RHU.0000000000000996DOI Listing
February 2019
3 Reads

Toxic Epidermal Necrolysis Induced by Leflunomide in a Patient With Rheumatoid Arthritis.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Rheumatology and Immunology The Affiliated Hospital of Inner Mongolia Medical University Hohhot, Department of Rheumatology and Immunology The Affiliated Hospital of Inner Mongolia Medical University Hohhot, China.

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http://dx.doi.org/10.1097/RHU.0000000000000997DOI Listing
February 2019
4 Reads

Kidney Biopsy From a Patient With Recurrent Scleroderma Renal Crisis During Pregnancy.

J Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Immunology, Allergy, and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.

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http://dx.doi.org/10.1097/RHU.0000000000000990DOI Listing
February 2019
1 Read

Acknowledgement to referees 2018.

Authors:

Clin Rheumatol 2019 Feb 5. Epub 2019 Feb 5.

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http://dx.doi.org/10.1007/s10067-019-04453-0DOI Listing
February 2019

Unmet needs in psoriatic arthritis patients receiving immunomodulatory therapy: results from a large multinational real-world study.

Clin Rheumatol 2019 Feb 4. Epub 2019 Feb 4.

Oregon Health & Science University, Portland, OR, USA.

Objective: There are limited data on therapy selection and switching in psoriatic arthritis (PsA). This 18 country, real-world study assessed use and switching of immunomodulatory therapy (biologic/apremilast), the extent of treatment failure and its association with reduced physical functioning, health-related quality of life (HRQoL), and work productivity and activity impairment (WPAI).

Methods: PsA patients under routine care and their treating physicians provided demographics, current therapy, reasons for switching, duration of first therapy, HRQoL, HAQ-DI, and WPAI. Read More

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http://dx.doi.org/10.1007/s10067-019-04446-zDOI Listing
February 2019
2 Reads

An overlooked rheumatologic manifestation of diabetes: diabetic cheiroarthropathy.

Clin Rheumatol 2019 Feb 2. Epub 2019 Feb 2.

Department of Physical Medicine and Rehabilitation, Cukurova University, Faculty of Medicine, Adana, Turkey.

Objectives: The objectives of the study were to analyze the clinical characteristic of diabetic cheiroarthropathy (DCA) in patients with type 1 diabetes mellitus (DM), type 2 DM, and prediabetes and to evaluate the frequency of DCA among groups.

Method: The cross-sectional study was conducted at the Division of Endocrinology and Metabolism outpatient clinic over a 14-month period. A total of 239 patients (160 female, 79 male), who had type 1 DM, type 2 DM, and prediabetes, were enrolled. Read More

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http://dx.doi.org/10.1007/s10067-019-04454-zDOI Listing
February 2019
1 Read

Proposal for a simple algorithm to differentiate adult-onset Still's disease with other fever of unknown origin causes: a longitudinal prospective study.

Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Internal Medicine, Division of Rheumatology, Hacettepe University Medical School, Sihhiye, 06100, Ankara, Turkey.

Objective: To identify several clinical and/or laboratory parameters which can differentiate adult-onset Still's disease (AOSD) from other causes of fever of unknown origin (FUO) and create a clinician-friendly algorithm for this purpose.

Methods: FUO patients hospitalized between March 2015 and September 2017 were recruited prospectively. AOSD patients diagnosed between 2001 and 2017 in our department were analyzed. Read More

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http://dx.doi.org/10.1007/s10067-019-04455-yDOI Listing
February 2019

MiR-5571-3p and miR-135b-5p, derived from analyses of microRNA profile sequencing, correlate with increased disease risk and activity of rheumatoid arthritis.

Clin Rheumatol 2019 Feb 1. Epub 2019 Feb 1.

Department of Rheumatology and Immunology, The First Affiliated Hospital of Wenzhou Medical University, South Baixiang, Ouhai District, Wenzhou, 325000, China.

Objectives: This study aimed to investigate microRNA (miRNA) expression profiles in synovium tissues of rheumatoid arthritis (RA) patients by RNA sequencing and to evaluate the values of dysregulated miRNAs in RA diagnosis and monitoring.

Methods: Thirty RA patients who underwent knee arthroscopy and 30 controls with knee trauma who underwent surgery were consecutively recruited, and synovium tissue samples of both groups were obtained during surgeries. In the exploration part, miRNA and mRNA expression profiles of 3 RA samples and 3 control samples were detected using RNA sequencing then followed by bioinformatic analyses. Read More

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http://dx.doi.org/10.1007/s10067-018-04417-wDOI Listing
February 2019

Frequency of functional gastrointestinal disorders in children with familial Mediterranean fever.

Clin Rheumatol 2019 Jan 31. Epub 2019 Jan 31.

Department of Pediatric Rheumatology, Cukurova University Faculty of Medicine, Saricam, 01331, Adana, Turkey.

Introduction: Familial Mediterranean fever (FMF) is characterized by self-limiting fever episodes usually accompanied by serositis, arthralgia, and arthritis. Functional gastrointestinal disorders (FGIDs) are diseases in which brain-gut axis and low-grade inflammation take part in pathogenesis. We aimed to study the FGIDs frequencies and possible risk factors for FGIDs in children with FMF. Read More

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http://dx.doi.org/10.1007/s10067-019-04452-1DOI Listing
January 2019
1 Read

Silicone breast implants and depression, fibromyalgia and chronic fatigue syndrome in a rheumatology clinic population.

Clin Rheumatol 2019 Jan 31. Epub 2019 Jan 31.

Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia.

Introduction: Silicone breast implants (SBI) may induce systemic autoimmune disease as part of autoimmune syndrome induced by adjuvants (ASIA). This syndrome bears similarities to fibromyalgia and chronic fatigue syndrome (CFS). We sought to determine whether there are any associations between SBI and depression, fibromyalgia and CFS in a rheumatology clinic population. Read More

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http://dx.doi.org/10.1007/s10067-019-04447-yDOI Listing
January 2019
1 Read

A Randomized Internet-Based Pilot Feasibility and Planning Study of Cherry Extract and Diet Modification in Gout.

J Clin Rheumatol 2019 Jan 23. Epub 2019 Jan 23.

Department of Epidemiology, School of Public Health, and.

Objective: The aim of this study was to conduct a 9-month pilot Internet randomized controlled trial (RCT) of cherry extract and diet modification in gout to assess the feasibility of an Internet study and obtain effect estimates.

Methods: After providing online informed consent in response to Internet advertisements and social media or clinic flyers, 84 people with physician-confirmed gout were randomized to either cherry extract 3,600 mg/d (n = 41) or dietitian-assisted diet modification for gout (n = 43). All study outcomes were collected via Internet and phone calls. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001004DOI Listing
January 2019
1 Read

Hydroxychloroquine is a safe and effective steroid-sparing agent for immune checkpoint inhibitor-induced inflammatory arthritis.

Clin Rheumatol 2019 Jan 30. Epub 2019 Jan 30.

Division of Rheumatology, Department of Medicine, University of Alberta, 8-120 Clinical Sciences Building, 8440 112 St NW, Edmonton, AB, T6G 2G3, Canada.

Immunotherapy for cancer treatment continues to evolve, and immune checkpoints have proven successful therapeutic targets. With success has come the challenge of managing the commonly associated immune-related toxicities. Arthralgias and arthritis are a common immune-related adverse event (IrAE), well described in the literature (Pardoll Nat Rev Cancer 12:252-264, 2012; Diesendruck and Benhar Drug Resist Updat 30:39-47, 2017; Cappelli et al. Read More

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http://dx.doi.org/10.1007/s10067-019-04451-2DOI Listing
January 2019

Pattern of sleep dysfunction in systemic lupus erythematosus: a cluster analysis.

Clin Rheumatol 2019 Jan 28. Epub 2019 Jan 28.

Unit of Allergy, Clinical Immunology and Rheumatology, Department of Medicine, Campus Bio-Medico University of Rome, via Alvaro del Portillo 21, 00128, Rome, Italy.

Objectives: To investigate how the different components of sleep dysfunction described in SLE patients combine together in sleep clusters.

Methods: We conducted a cross-sectional study on a perspective cohort of 79 SLE patients (mean age 8.2 ± 14. Read More

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http://dx.doi.org/10.1007/s10067-018-04410-3DOI Listing
January 2019

Low-dose rituximab as induction therapy for ANCA-associated vasculitis.

Clin Rheumatol 2019 Jan 25. Epub 2019 Jan 25.

Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao Miyamae, Kawasaki, Kanagawa, 216-8511, Japan.

Administration of four once-weekly doses of 375 mg/m rituximab (RTX) is commonly used as remission induction therapy for ANCA-associated vasculitis (AAV). Low-dose RTX has been recently shown to produce closely similar results to conventional treatments in other autoimmune diseases. However, the therapeutic potential of this approach in AAV remains largely unknown. Read More

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http://link.springer.com/10.1007/s10067-019-04443-2
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http://dx.doi.org/10.1007/s10067-019-04443-2DOI Listing
January 2019
6 Reads

Performance and calibration of the algorithm ASSIGN in predicting cardiovascular disease in Italian patients with psoriatic arthritis.

Clin Rheumatol 2019 Jan 24. Epub 2019 Jan 24.

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine, University of Naples Federico II, Naples, Italy.

The increased cardiovascular (CV) risk is one of the major challenges in the management of patients with psoriatic arthritis (PsA). Recently, EULAR suggested to adapt the already available CV risk algorithms with a 1.5 multiplication factor in all the patients with rheumatoid arthritis (RA), but it is still uncertain if this adaptation could also be applied to patients with PsA. Read More

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http://dx.doi.org/10.1007/s10067-019-04442-3DOI Listing
January 2019
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Axial spondyloarthritis in the USA: diagnostic challenges and missed opportunities-comments on the article by Danve A & Deodhar A.

Authors:
Sasan Fallahi

Clin Rheumatol 2019 Jan 24. Epub 2019 Jan 24.

Internal Medicine Division, Baharloo Hospital, Tehran University of Medical Sciences, Behdari Street, South Kargar Street, Tehran, Iran.

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http://dx.doi.org/10.1007/s10067-019-04444-1DOI Listing
January 2019

Prevalence and Incidence of Rheumatoid Arthritis in Canadian First Nations and Non-First Nations People: A Population-Based Study.

J Clin Rheumatol 2019 Jan 22. Epub 2019 Jan 22.

From the Departments of Internal Medicine and.

Background: The aim of this study was to determine the prevalence, incidence, and onset age at rheumatoid arthritis (RA) diagnosis in First Nations (FN) and non-FN populations in Manitoba, Canada.

Methods: Population-based administrative health records from April 1, 1995, to March 31, 2010, were accessed for all Manitobans. The FN population was identified using the Federal Indian Registry File. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001006DOI Listing
January 2019

A survey of traditional Chinese medicine use among rheumatoid arthritis patients: a claims data-based cohort study.

Clin Rheumatol 2019 Jan 22. Epub 2019 Jan 22.

Department of Medical Research, Dalin Tzuchi Hospital, The Buddhist Tzuchi Medical Foundation, 2 Minsheng Road, Dalin Township, Chiayi, 62247, Taiwan.

Introduction/objectives: Traditional Chinese medicine (TCM) is commonly used for symptom relief in patients with chronic diseases. Nevertheless, large-scale surveys focusing on the utilization of TCM among patients with rheumatoid arthritis (RA) are limited, especially in Taiwan, where TCM is highly popular. This cohort study aimed to describe the utilization of TCM and determine the factors related to TCM usage among RA patients. Read More

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http://dx.doi.org/10.1007/s10067-018-04425-wDOI Listing
January 2019

Gout and healthcare utilization and complications after hip arthroplasty: a cohort study using the US National Inpatient Sample (NIS).

Clin Rheumatol 2019 Jan 22. Epub 2019 Jan 22.

Department of Medicine at School of Medicine, University of Alabama at Birmingham, 1720 Second Ave. South, Birmingham, AL, 35294-0022, USA.

Little is known about the effect of gout on in-hospital complications and healthcare utilization after total hip arthroplasty (THA). We used the 1998-2014 U.S. Read More

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http://link.springer.com/10.1007/s10067-019-04434-3
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http://dx.doi.org/10.1007/s10067-019-04434-3DOI Listing
January 2019
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Numerous Cotton Wool Spots From Giant Cell Arteritis.

J Clin Rheumatol 2019 Jan 18. Epub 2019 Jan 18.

From the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/RHU.0000000000000995DOI Listing
January 2019
3 Reads

Synovial Biopsy in the Diagnosis of Crystal-Associated Arthropathies.

J Clin Rheumatol 2019 Jan 18. Epub 2019 Jan 18.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI.

Background/ Objective: This study seeks to assess the utility of synovial biopsy in the diagnosis of crystal-associated arthropathies (CAAs) in a clinical setting.

Methods: In this retrospective study, we reviewed biopsy reports involving synovial tissue between 1988 and 2015. We then reviewed the records of patients where the biopsy was performed for a clinical suspicion of CAA-the clinical group-and calculated the frequency of a positive diagnosis. Read More

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http://dx.doi.org/10.1097/RHU.0000000000000993DOI Listing
January 2019
3 Reads