11,823 results match your criteria Clinical Rheumatology[Journal]


Oral health-related quality of life among individuals with rheumatoid arthritis.

Clin Rheumatol 2019 Apr 19. Epub 2019 Apr 19.

Department of Oral Pathology and Surgery, Faculty of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Objective: To evaluate the oral health-related quality of life (OHRQoL) of individuals with rheumatoid arthritis (RA) in comparison with individuals with no RA.

Method: A cross-sectional study was carried out with 112 individuals distributed into two groups. Group 1 (G1) consisted of 42 RA individuals and group 2 (G2) consisted of 70 individuals without RA. Read More

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http://link.springer.com/10.1007/s10067-019-04555-9
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http://dx.doi.org/10.1007/s10067-019-04555-9DOI Listing
April 2019
1 Read

Elusive trochanteric bursitis relief.

Authors:
Bruce Rothschild

Clin Rheumatol 2019 Apr 19. Epub 2019 Apr 19.

Indiana University, Carnegie Museum, 4400 Forbes Ave, Pittsburgh, PA, 15213, USA.

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http://link.springer.com/10.1007/s10067-019-04560-y
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http://dx.doi.org/10.1007/s10067-019-04560-yDOI Listing
April 2019
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Comparison of clinical presentation and incidence of cardiopulmonary complications between male and female Thai patients with early systemic sclerosis: inception cohort study.

Clin Rheumatol 2019 Apr 19. Epub 2019 Apr 19.

Division of Diagnostic Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Objectives: To determine the prevalence of clinical manifestations and incidence rate of cardiopulmonary complications in a comparison between men and women with early SSc.

Methods: An inception cohort of early-SSc patients at the Rheumatology Clinic, Maharaj Nakorn Chiang Mai Hospital, between January 2010 and June 2016, was used. All patients were assessed for clinical manifestations and underwent ECG, echocardiography, and HRCT at the study entry and then annually. Read More

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http://dx.doi.org/10.1007/s10067-019-04551-zDOI Listing

Extensive Persistent Panniculitis in the Context of Dermatomyositis.

J Clin Rheumatol 2019 Apr 12. Epub 2019 Apr 12.

Dermatology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/RHU.0000000000001058DOI Listing
April 2019
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Bilateral Quadriceps Tendon Rupture.

J Clin Rheumatol 2019 Apr 12. Epub 2019 Apr 12.

Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1097/RHU.0000000000001037DOI Listing

Physician's Experience and Disease Activity Affect the Impact of Ultrasound on the Treatment Decision in Rheumatoid Arthritis.

J Clin Rheumatol 2019 Apr 12. Epub 2019 Apr 12.

Division of Musculoskeletal and Rheumatic Disorders, Instituto Nacional de Rehabilitación y Ortopedia, Tlalpan, Mexico City, Mexico.

Background/objective: The aim of this cross-sectional study was to explore which factors affect the impact of musculoskeletal ultrasound (MUS) on the treatment proposal among rheumatologists with different grade of experience.

Methods: Sixteen clinical vignettes summarized data from respective rheumatoid arthritis (RA) outpatients; vignettes included clinical evaluation and a blank section for a first treatment proposal; MUS information was then added, based on German Ultrasound score, followed by a blank section for treatment re-consideration, if applicable. During a 6 months period, each vignette was concomitantly presented to six trainees and six senior rheumatologists (SR); three SR had ≥15 years of experience. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001036DOI Listing
April 2019
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Suppurative Cervical Adenitis Due to Streptococcus pneumoniae Infection in Systemic Lupus Erythematosus.

J Clin Rheumatol 2019 Apr 12. Epub 2019 Apr 12.

Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, The Pennsylvania State University College of Medicine, and.

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http://dx.doi.org/10.1097/RHU.0000000000001035DOI Listing

Causes of fetal third-degree atrioventricular block and use of hydroxychloroquine in pregnant women with Ro/La antibodies.

Clin Rheumatol 2019 Apr 17. Epub 2019 Apr 17.

Sección Reumatología, Servicio de Clínica Médica, Hospital Italiano de Buenos Aires, Peron 4190 (C1199ABB), Buenos Aires, Argentina.

Introduction/objectives: Complete congenital atrioventricular block (AVB) may be due to cardiac malformations or the presence of maternal antibodies (autoimmune AVB). Our objective was to estimate the prevalence of autoimmune AVB among all AVB in newborns treated at our hospital. Secondly, we estimated the prevalence of AVB among mothers with anti-Ro/La antibodies and examined the relationship of those fetal AVB with mother's use of hydroxychloroquine during pregnancy. Read More

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http://dx.doi.org/10.1007/s10067-019-04556-8DOI Listing
April 2019
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Value of serum procalcitonin for the diagnosis of bacterial septic arthritis in daily practice in rheumatology.

Clin Rheumatol 2019 Apr 16. Epub 2019 Apr 16.

CHRU Jean Minjoz, Service de Rhumatologie, 3 Boulevard Alexandre Fleming, 25000, Besancon, France.

Introduction/objectives: Septic arthritis is a diagnostic and therapeutic emergency because of a high morbidity and mortality. Nevertheless, the etiologic diagnosis is often difficult. The aim of our study was to determine if serum procalcitonin was a discriminatory biomarker in case of arthritis of undetermined etiology. Read More

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http://dx.doi.org/10.1007/s10067-019-04542-0DOI Listing
April 2019
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Mortality in patients with systemic lupus erythematosus in Colombia: a case series.

Clin Rheumatol 2019 Apr 15. Epub 2019 Apr 15.

GIRAT: Grupo de Investigación en Reumatología, Autoinmunidad y Medicina Traslacional, Fundación Valle del Lili and Universidad Icesi, Cali, Colombia.

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease associated with high mortality rates. This study aimed to describe the main causes of death in a case series of SLE patients attended in a single center in Colombia.

Methods: We conducted a retrospective review and analysis of records of SLE patients who died between January 2011 and June 2017. Read More

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http://link.springer.com/10.1007/s10067-019-04546-w
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http://dx.doi.org/10.1007/s10067-019-04546-wDOI Listing
April 2019
2 Reads

Exceptional association of hypocomplementemic urticarial vasculitis syndrome (HUVS) and symptomatic pulmonary histoplasmosis: a case-based literature review.

Clin Rheumatol 2019 Apr 13. Epub 2019 Apr 13.

Departments of Medicine and Rheumatology, MetroHealth Medical Center, Cleveland, OH, USA.

Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare type III hypersensitivity disorder characterized by urticarial vasculitis and prolonged hypocomplementemia. Individuals with HUVS may also have joint involvement, pulmonary manifestations, ocular disease, kidney inflammation, or any other form of organ involvement. Hypocomplementemia, the presence of C1q antibody in the serum, and urticarial vasculitis are the keys to the diagnosis of HUVS. Read More

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http://dx.doi.org/10.1007/s10067-019-04548-8DOI Listing
April 2019
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Think autoimmunity, breath autoimmunity, and learn autoimmunity.

Clin Rheumatol 2019 Apr 12. Epub 2019 Apr 12.

Division of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Technion, Haifa, Israel.

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http://dx.doi.org/10.1007/s10067-019-04540-2DOI Listing

A misdiagnosed case of antisynthetase syndrome complicated by myocarditis: when the cardiologist deals with rheumatology.

Clin Rheumatol 2019 Apr 11. Epub 2019 Apr 11.

Department of Cardiology, San Giovanni di Dio Hospital, Via Fatebenefratelli, 34, 34170, Gorizia, GO, Italy.

We report a case of a 56-year-old woman with an alleged diagnosis of an acute coronary syndrome that was later correctly identified in our Cardiology Unit as antisynthetase syndrome (AS) with inflammatory cardiac involvement. In this case report, we focus on clinical features of this rare autoimmune disease aiming to provide useful tips to achieve correct differential diagnosis according to updated international guidelines and recommendations, especially in cases of concurrent disease-related myocarditis. Read More

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http://link.springer.com/10.1007/s10067-019-04527-z
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http://dx.doi.org/10.1007/s10067-019-04527-zDOI Listing
April 2019
4 Reads

Seasonal variations of Google searches for joint swelling: implications for patient-reported outcomes.

Clin Rheumatol 2019 Apr 11. Epub 2019 Apr 11.

Department of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1007/s10067-019-04534-0DOI Listing

Correction to: Predictors of abatacept retention over 2 years in patients with rheumatoid arthritis: results from the real-world ACTION study.

Clin Rheumatol 2019 Apr 11. Epub 2019 Apr 11.

Speciality Development Immunology, Bristol-Myers Squibb, Rueil-Malmaison, France.

The article listed above was initially published with incorrect copyright information. Upon publication of this Correction, the copyright of this article changed to "The Author(s)". The original article has been corrected. Read More

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http://dx.doi.org/10.1007/s10067-019-04545-xDOI Listing
April 2019
2 Reads
1.774 Impact Factor

Infliximab for the treatment of refractory polyarteritis nodosa.

Clin Rheumatol 2019 Apr 10. Epub 2019 Apr 10.

Rheumatology Unit, Bnai-Zion Medical Center, Haifa, Israel.

Polyarteritis nodosa (PAN) is a necrotizing vasculitis predominantly affecting medium and small size arteries. Cyclophosphamide, a drug with narrow therapeutic range and poor safety profile, constitutes the treatment of choice for PAN vasculitis with major organ involvement. To describe our clinical experience in treating refractory PAN with infliximab (a TNF inhibitor), a drug with good tolerability and better safety profile than cyclophosphamide. Read More

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http://dx.doi.org/10.1007/s10067-019-04474-9DOI Listing
April 2019
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Validation of the Chinese version of joint protection self-efficacy scale in patients with rheumatoid arthritis.

Clin Rheumatol 2019 Apr 10. Epub 2019 Apr 10.

Joint Department, The 2nd Ward of Joint Surgery, Tianjin Hospital, 406 Jiefangnan Rd, Tianjin, 300211, People's Republic of China.

Objective: To develop and validate the Chinese version of the Joint Protection Self-Efficacy Scale (CJP-SES) in patients with rheumatoid arthritis (RA) in China.

Method: (1) Translation of the original German/English version JP-SES and cultural adaptation into the Chinese language; (2)Validation of the CJP-SES with the Chinese versions of the Arthritis Self-Efficacy Scale-8 (ASES-8), the Laffrey Health Conception Scale (LHCS), 10-item Perceived Efficacy in Patient-Physician Interactions Scale (PEPPI-10), Disease Activity Score-28 (DAS-28) and Health Assessment Questionnaire (HAQ). Instrument measurement included reliability testing, item generation, construct validity, test-retest reliability, and correlation with other measurements. Read More

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http://link.springer.com/10.1007/s10067-019-04510-8
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http://dx.doi.org/10.1007/s10067-019-04510-8DOI Listing
April 2019
5 Reads

Brief report: the disability of chronic chikungunya arthritis.

Clin Rheumatol 2019 Apr 8. Epub 2019 Apr 8.

Section of Rheumatology, Allergy and Clinical Immunology, Yale University School of Medicine, New Haven, CT, USA.

In 50% of patients, chikungunya fever (CHIKF) is followed by arthritic pain that is often chronic, painful, and disabling. To better define the spectrum of pain and disability in chronic CHIK arthritis (CCA), we evaluated 35 consecutive CCA patients seen in a Brazilian rheumatology clinic, using a pain Visual Analog Scale and the Health Assessment Questionnaire Disability Index. In our patients, pain and disability levels were of the same magnitude as are seen in other serious rheumatic diseases. Read More

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http://dx.doi.org/10.1007/s10067-019-04529-xDOI Listing
April 2019
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Burden of comorbidities in South Africans with systemic lupus erythematosus.

Clin Rheumatol 2019 Apr 8. Epub 2019 Apr 8.

Division of Rheumatology, Chris Hani Baragwanath Academic Hospital and University of the Witwatersrand, P.O. Bertsham, Johannesburg, 2013, South Africa.

Introduction: To investigate the prevalence and spectrum of comorbidities in South Africans with systemic lupus erythematosus (SLE).

Patients And Methods: A nested case-control study of a known alive group (AG) and deceased group (DG) of 200 and 40 patients, respectively, matched for age and sex, attending a tertiary Lupus Clinic. Comorbidities that were documented included, but not restricted to, those listed in the Charlson comorbidity index (CCI). Read More

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http://dx.doi.org/10.1007/s10067-019-04511-7DOI Listing
April 2019
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Extractable synovial fluid in inflammatory and non-inflammatory arthritis of the knee.

Clin Rheumatol 2019 Apr 5. Epub 2019 Apr 5.

Department of Internal Medicine, Division of Rheumatology and School of Medicine, MSC 10 5550, 5th FL ACC, University of New Mexico Health Sciences Center, Albuquerque, NM, 87131, USA.

Introduction/objectives: We hypothesized that mechanical compression of the knee in rheumatoid arthritis (RA) would mobilize occult extractable fluid and improve arthrocentesis success.

Methods: Sixty-seven consecutive knees with RA and 186 knees with OA and were included. Conventional arthrocentesis was performed and success and volume (milliliters) determined; the needle was left intraarticularly, and mechanical compression was applied with an elastomeric knee brace. Read More

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http://dx.doi.org/10.1007/s10067-019-04524-2DOI Listing
April 2019
6 Reads

Azathioprine-Induced Melanonychia.

J Clin Rheumatol 2019 Apr 3. Epub 2019 Apr 3.

From the Allergy Immunology Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1097/RHU.0000000000001031DOI Listing
April 2019
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High Circulating Levels of IL-4 and IL-10 in Progressive Pseudorheumatoid Dysplasia Patient.

J Clin Rheumatol 2019 Apr 3. Epub 2019 Apr 3.

From the IRCCS Istituto Ortopedico Rizzoli, Laboratorio di Immunoreumatologia e Rigenerazione Tissutale, Bologna.

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http://dx.doi.org/10.1097/RHU.0000000000001032DOI Listing

Ultrasound as a Useful Tool in the Diagnosis of Rheumatoid Arthritis in Patients With Undifferentiated Arthritis.

J Clin Rheumatol 2019 Apr 3. Epub 2019 Apr 3.

Center of Rheumatoid Arthritis, BIOMAB, Bogota, Colombia.

Background: Nowadays, rheumatologists face challenges in finding an effective method to classify and treat patients with undifferentiated arthritis (UA). There is a need for new tools that could ensure accurate characterization of inflammatory processes in these patients.

Objective: The aim of this study was to investigate if a characterization of UA patients using ultrasound (US) may help to fulfill the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) rheumatoid arthritis (RA) classification criteria in a real-life cohort. Read More

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http://dx.doi.org/10.1097/RHU.0000000000001034DOI Listing
April 2019
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Subchondral Cyst-Like Lesion of the Hand in a Patient With Rheumatoid Arthritis.

J Clin Rheumatol 2019 Apr 3. Epub 2019 Apr 3.

From the Division of Rheumatology, Agios Andreas Hospital, Patras, Greece.

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http://dx.doi.org/10.1097/RHU.0000000000001033DOI Listing
April 2019
3 Reads

18FDG PET for Detecting Renal Granulomatous Localization: Illustration of Granulomatosis With Polyangiitis and Sarcoidosis.

J Clin Rheumatol 2019 Apr 3. Epub 2019 Apr 3.

AP-HP, Sorbonne Université Hôpital Saint Antoine Service de Médecine Interne and Inflammation-Immunopathology-Biotherapy Department, Paris Service de Médecine Nucléaire Université Paris 13, Bobigny, France AP-HP, Sorbonne Université Hôpital Saint Antoine Service de Médecine Interne and Inflammation-Immunopathology-Biotherapy Department, Paris

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http://dx.doi.org/10.1097/RHU.0000000000001003DOI Listing

Ankle pain in rheumatoid arthritis: comparison of clinical and sonographic findings.

Clin Rheumatol 2019 Apr 2. Epub 2019 Apr 2.

Clínica Reumatológica, Università Politecnica delle Marche, Ospedale "Carlo Urbani", Via Aldo Moro 25, 60035, Jesi Ancona, Italy.

To describe the prevalence and distribution of clinical and ultrasound (US) pathological findings at ankle level and to compare them, in patients with rheumatoid arthritis (RA). This is a descriptive, cross-sectional study assessing patients diagnosed with RA according to the 2010 ACR criteria, who were recruited consecutively and independently of disease status or treatment and of the presence of pain at ankle level. Clinical and US findings were acquired by two independent rheumatologists. Read More

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http://dx.doi.org/10.1007/s10067-019-04532-2DOI Listing
April 2019
1 Read

Cardiac and cardiovascular morbidities in patients with psoriatic arthritis: a population-based case control study.

Clin Rheumatol 2019 Apr 1. Epub 2019 Apr 1.

Rheumatology Unit, Carmel Medical Center, 7 Michal Street, 34362, Haifa, Israel.

Objective: To assess the prevalence of risk factors associated with cardiovascular disease (CVD) and CVD-related morbidity in a large Middle-Eastern psoriatic arthritis (PsA) cohort.

Method: A retrospective case control study was conducted using Israel's largest health care provider's patient database from 2000 to 2013. For each patient with PsA, 10 patients with no history of psoriasis or arthritis were matched for age and sex. Read More

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http://dx.doi.org/10.1007/s10067-019-04528-yDOI Listing
April 2019
2 Reads

Low-dose cyclosporine for active lupus nephritis: a dose titration approach.

Clin Rheumatol 2019 Apr 1. Epub 2019 Apr 1.

Nephrology Unit, Department of Medicine, Rajavithi Hospital, College of Medicine, Rangsit University, Rajavithi Road, Bangkok, 10400, Thailand.

Objective: Achievement of complete renal remission (CR) is an important goal in lupus nephritis (LN) treatment. The use of cyclosporine (CsA) for active LN has been challenged because of variations in CsA doses and reports of adverse reactions (AR).

Method: A cohort of 62 patients with active LN (induction-resistant LN and flared LN) who were treated with CsA was evaluated. Read More

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http://dx.doi.org/10.1007/s10067-019-04469-6DOI Listing
April 2019
2 Reads

Composite measures of physical activity and pain associate better with functional assessments than pain alone in knee osteoarthritis.

Clin Rheumatol 2019 Mar 30. Epub 2019 Mar 30.

Department of Medicine, Duke University Medical Center, Durham, NC, USA.

Introduction: Recent research showed that physical activity (PA)-adjusted pain measures were more strongly associated with radiographic osteoarthritis (OA) severity than an unadjusted pain measure. This exploratory study examined whether PA-adjusted pain measures were more closely associated with other key OA-related measures, compared to unadjusted pain scores.

Method: Participants were 122 Veterans (mean age = 61. Read More

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http://dx.doi.org/10.1007/s10067-019-04530-4DOI Listing
March 2019
2 Reads

Crystal-proven gout patients have an increased mortality due to cardiovascular diseases, cancer, and infectious diseases especially when having tophi and/or high serum uric acid levels: a prospective cohort study.

Clin Rheumatol 2019 Mar 30. Epub 2019 Mar 30.

Department of Rheumatology, VieCuri Medical Centre, Venlo, Tegelseweg 210, 5912, BL, Venlo, The Netherlands.

Objective: To investigate the cause-specific mortality and the possible involved clinical characteristics with increased mortality in a cohort of 700 patients with crystal-proven gout. The cause-specific mortality of gout was compared to the mortality of the general population.

Methods: Patients with arthritis referred for diagnosis were consecutively included in the Gout Arnhem-Liemers Cohort (GOAL). Read More

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http://dx.doi.org/10.1007/s10067-019-04520-6DOI Listing
March 2019
2 Reads
1.774 Impact Factor

Gout and chronic pain in older adults: a Medicare claims study.

Clin Rheumatol 2019 Mar 29. Epub 2019 Mar 29.

Department of Medicine at School of Medicine, University of Alabama at Birmingham, 510 20th Street South, FOT 805B, Birmingham, AL, 35294, United States.

To assess if gout is associated with a higher risk of incident chronic pain. This study used the 2006-2012 Medicare claims data. We used multivariable-adjusted Cox regression analyses to examine the association of pre-existing diagnosis of gout with incident (new) diagnosis of chronic pain, adjusting for demographics, medical comorbidity, and use of common medications for cardiovascular disease and gout. Read More

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http://dx.doi.org/10.1007/s10067-019-04526-0DOI Listing
March 2019
1 Read

Rheumatic associations of autoimmune thyroid disease: a systematic review.

Clin Rheumatol 2019 Mar 29. Epub 2019 Mar 29.

Albert Einstein College of Medicine, Bronx, NY, USA.

To investigate specific disease patterns in the rheumatic manifestations associated with autoimmune thyroid disease (AITD) through a systematic literature review. We performed a systematic review using the Medline OVID, PubMed, EMBASE, and Web of Science databases through May 2018 for experimental and observational studies that explored the association of AITD with degenerative joint disease (DJD), osteoarthritis (OA), chronic widespread pain (CWP) and fibromyalgia syndrome (FMS), and seronegative inflammatory arthritis (IA). A total of 2132 articles were identified. Read More

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http://dx.doi.org/10.1007/s10067-019-04498-1DOI Listing
March 2019
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Rheumatoid arthritis and risk of anxiety: a meta-analysis of cohort studies.

Clin Rheumatol 2019 Mar 28. Epub 2019 Mar 28.

Department of Rheumatology, The Second Affiliated Hospital of Nanchang University, No.1, Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.

Objectives: Rheumatoid arthritis (RA) may increase the risk of anxiety, but results from prior studies have no consensus. Our study aimed to evaluate the relationship between RA and incident anxiety by using a quantitative meta-analysis.

Methods: A number of databases were used to gather relevant information; they included PubMed, EMBASE, and Web of Science, with the publication date of articles limited up to July 23, 2018. Read More

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http://dx.doi.org/10.1007/s10067-019-04502-8DOI Listing
March 2019
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Hypertension is associated with increased age at the onset of psoriasis and a higher body mass index in psoriatic disease.

Clin Rheumatol 2019 Mar 28. Epub 2019 Mar 28.

Dermatology Division, Hospital Alvarez Buylla, Mieres, Asturias, Spain.

Background And Aims: High blood pressure (HBP) is a common comorbidity in psoriatic disease. Some studies indicate a higher prevalence of HBP among arthritis patients, in relation to psoriasis alone, within the psoriatic spectrum. Our objective was to study the prevalence of HBP in both types of patients as well as to analyse the factors associated with it. Read More

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http://link.springer.com/10.1007/s10067-019-04519-z
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http://dx.doi.org/10.1007/s10067-019-04519-zDOI Listing
March 2019
7 Reads

Value of hematological indices versus VEGF as biomarkers of activity in Behçet's disease.

Clin Rheumatol 2019 Mar 28. Epub 2019 Mar 28.

Clinical Pathology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Objective: The aim of this study is to investigate the value of several hematological indices, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), red blood cell distribution width (RDW), and mean platelet volume (MPV), versus vascular endothelial growth factor (VEGF) as biomarkers of activity in Behçet's disease (BD).

Methods: This study included 96 adult BD patients recruited from the Rheumatology Outpatient Clinic, Kasr Al-Ainy Hospital, Cairo University, and 60 healthy subjects as controls. Assessment of BD activity was done using the Behçet's Disease Current Activity Form (BDCAF). Read More

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http://dx.doi.org/10.1007/s10067-019-04513-5DOI Listing

First trimester combined screening in patients with systemic lupus erythematosus: impact of pre-analytical variables on risk assessment.

Clin Rheumatol 2019 Mar 28. Epub 2019 Mar 28.

Harris Birthright Research Center of Fetal Medicine, King's College Hospital, London, UK.

Background: Prenatal diagnosis of fetal trisomy 21 and other chromosomal abnormalities is based on invasive tests, such as amniocentesis and chorionic villus sampling, which are carried out in women identified through screening as being at high risk for these abnormalities. The most widely used method of screening is the first-trimester combined test which utilizes maternal age, and measurements of fetal nuchal translucency thickness (NT) and maternal serum pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (hCG).

Objectives: To assess the influence of SLE on the levels of NT, PAPP-A, and β-hCG and whether any alterations in such levels may increase the rate of false positives and the subsequent number of invasive tests. Read More

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http://link.springer.com/10.1007/s10067-019-04525-1
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http://dx.doi.org/10.1007/s10067-019-04525-1DOI Listing
March 2019
3 Reads
1.774 Impact Factor

Evolving patterns of reactive arthritis.

Clin Rheumatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, Canada.

Objective: To characterize rheumatologists' perspectives on evolving trends of reactive arthritis (ReA).

Methods: After ethics approval, 548 members of the Canadian Rheumatology Association were surveyed with 37 questions covering their demographic information, subspecialty, level of experience, practice setting and opinions on prevalence, treatment, and causes of ReA. Results were analyzed with descriptive statistics. Read More

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http://dx.doi.org/10.1007/s10067-019-04522-4DOI Listing
March 2019
1 Read

Patients with early-stage knee osteoarthritis and knee pain have decreased hip abductor muscle strength while descending stairs.

Clin Rheumatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Introduction/objectives: This study aimed to investigate the association between hip abductor muscle strength and knee pain in patients with early-stage knee osteoarthritis (OA) while ascending and descending stairs.

Method: This cross-sectional study included individuals with early-stage knee OA (Kellgren/Lawrence grades 1 or 2). Knee pain while ascending and descending stairs was evaluated using a knee OA-related health domain measure (Japanese Knee Osteoarthritis Measure). Read More

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http://dx.doi.org/10.1007/s10067-019-04523-3DOI Listing

PANLAR consensus statement on biosimilars.

Clin Rheumatol 2019 Mar 27. Epub 2019 Mar 27.

American College of Rheumatology, 2200 Lake Boulevard NE, Atlanta, GA, 303192200, USA.

Introduction: Biologics have improved the treatment of rheumatic diseases, resulting in better outcomes. However, their high cost limits access for many patients in both North America and Latin America. Following patent expiration for biologicals, the availability of biosimilars, which typically are less expensive due to lower development costs, provides additional treatment options for patients with rheumatic diseases. Read More

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http://dx.doi.org/10.1007/s10067-019-04496-3DOI Listing

Accuracy of neutrophil CD64 expression in diagnosing infection in patients with autoimmune diseases: a meta-analysis.

Clin Rheumatol 2019 Mar 27. Epub 2019 Mar 27.

Phase I Clinical Trial Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.

We aimed to systematically evaluate the accuracy of nCD64 in diagnosing infection in patients with autoimmune diseases. Studies were searched in PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Wanfang, and Chongqing VIP databases up to October 2018. There was no restriction for language and age. Read More

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http://dx.doi.org/10.1007/s10067-019-04518-0DOI Listing

Efficacy and safety profile of intravenous tocilizumab versus intravenous abatacept in treating female Saudi Arabian patients with active moderate-to-severe rheumatoid arthritis.

Clin Rheumatol 2019 Mar 26. Epub 2019 Mar 26.

Rheumatology & Rehabilitation Department, Faculty of Medicine, Zagazig University, University Street, Zagazig, 44519, Egypt.

Objectives: To compare the efficacy and safety of tocilizumab with those of abatacept in patients with active rheumatoid arthritis not responding to anti-tumor necrosis factor therapy.

Methods: A prospective, open-label study was carried out on adult females with moderate-to-severe rheumatoid arthritis. Patients were randomly assigned to receive either intravenous tocilizumab or abatacept treatment. Read More

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http://link.springer.com/10.1007/s10067-019-04508-2
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http://dx.doi.org/10.1007/s10067-019-04508-2DOI Listing
March 2019
2 Reads

Clinical characteristics of rheumatoid arthritis patients with peripheral neuropathy and potential related risk factors.

Clin Rheumatol 2019 Mar 25. Epub 2019 Mar 25.

Department of Rheumatology, Linyi People's Hospital, No. 27 East Jiefang Road, Linyi, 276000, Shandong, China.

Objectives: To investigate potential risk factors of peripheral neuropathy (PN) in rheumatoid arthritis patients (RA).

Methods: Eighty-eight patients with RA were enrolled in this study, including patients with PN (n = 44; 28 patients with multiple nerves (MN) involvement and 16 patients with single nerve (SN) involvement) and without (n = 44) peripheral neuropathy were enrolled. Their clinical features were comprehensively collected including symptoms/signs, lab results, electromyogram data. Read More

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http://link.springer.com/10.1007/s10067-019-04521-5
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http://dx.doi.org/10.1007/s10067-019-04521-5DOI Listing
March 2019
6 Reads

PRL -1149T allele (rs1341239) is associated with decreased risk of rheumatoid arthritis in population from southern Mexico: analysis of mRNA expression and PRL serum levels.

Clin Rheumatol 2019 Mar 25. Epub 2019 Mar 25.

Instituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Independencia Oriente, 44340, Guadalajara, Jalisco, Mexico.

Introduction: Prolactin (PRL) is a sex hormone with immunomodulatory properties, and it is associated with the clinical activity of rheumatoid arthritis (RA). The -1149G>T polymorphism at the prolactin (PRL) gene has been associated with autoimmune diseases, but its functional effect is unclear.

Objective: To analyze the association of the PRL -1149G>T polymorphism with disease susceptibility, mRNA, and protein expression of PRL in RA patients from Southern Mexico. Read More

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http://dx.doi.org/10.1007/s10067-019-04517-1DOI Listing
March 2019
1 Read

Plasma let-7i, miR-16, and miR-221 levels as candidate biomarkers for the assessment of ankylosing spondylitis in Mexican patients naïve to anti-TNF therapy.

Clin Rheumatol 2019 Mar 25. Epub 2019 Mar 25.

Department of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano 1, Sección XVI, Tlalpan, 14080, Mexico City, Mexico.

Novel biomarkers are needed for the diagnosis and clinical assessment of ankylosing spondylitis (AS). Our objective was to investigate plasma microRNAs differentially expressed between AS patients and controls and to evaluate their potential as biomarkers in Mexican subjects. A cross-sectional study including 15 AS patients naïve to anti-TNF therapy and 13 controls was performed. Read More

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http://dx.doi.org/10.1007/s10067-019-04509-1DOI Listing
March 2019
1 Read

Stiff-Types.

Authors:

J Clin Rheumatol 2019 Apr;25(3):155

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http://dx.doi.org/10.1097/RHU.0000000000001014DOI Listing

Are extra-spinal symptoms associated with quality of life in patients with axial spondyloarthritis? A 1-year follow-up study.

Clin Rheumatol 2019 Mar 23. Epub 2019 Mar 23.

Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

To assess the extent to which a history of extra-spinal symptoms (including peripheral arthritis, heel enthesitis, or dactylitis) (HPED) is associated with quality of life (QoL) in patients with axial spondyloarthritis (axSpA) at baseline and 1-year follow-up. We analyzed data from 138 patients with axSpA from a tertiary referral center in Singapore, seen between 2011 and 2015. Demographic, clinical variables, and patient-reported outcomes [Ankylosing Spondylitis Quality of Life (ASQoL) and SF-36] at baseline and 1-year follow-up were collected. Read More

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http://dx.doi.org/10.1007/s10067-019-04514-4DOI Listing
March 2019
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1.774 Impact Factor

Comparison of the 2017 EULAR/ACR criteria with Bohan and Peter criteria for the classification of idiopathic inflammatory myopathies.

Clin Rheumatol 2019 Mar 22. Epub 2019 Mar 22.

Department of Clinical Immunology and Rheumatology, St John's Medical College, Sarjapur Road, Bengaluru, 560034, India.

Bohan and Peter is the oldest criteria for the classification of idiopathic inflammatory myopathies (IIM). Recently, 2017 EULAR/ACR criteria were introduced which were validated against a control group. The objective of this study was to assess the performance of the 2017 EULAR/ACR criteria in retrospective cohort of adult and juvenile idiopathic inflammatory myopathies and compare with Bohan and Peter criteria. Read More

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http://dx.doi.org/10.1007/s10067-019-04512-6DOI Listing
March 2019
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Ankylosing spondylitis is associated with aberrant DNA methylation of IFN regulatory factor 8 gene promoter region.

Clin Rheumatol 2019 Mar 21. Epub 2019 Mar 21.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui, China.

Objectives: To investigate the role of methylation levels of the IFN regulatory factor 8 (IRF8) gene promoter in the development of ankylosing spondylitis (AS).

Methods: In this study, we compared the methylation levels of the IRF8 gene promoter between 99 AS patients and 99 healthy controls using MethylTarget approach. Quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) was performed to compare the mRNA levels of the IRF8 gene in the other 19 AS patients and 19 healthy controls. Read More

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http://dx.doi.org/10.1007/s10067-019-04505-5DOI Listing
March 2019
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1.774 Impact Factor

Hypotension in a Febrile Child-Beware of Kawasaki Disease Shock Syndrome.

J Clin Rheumatol 2019 Mar 20. Epub 2019 Mar 20.

From the Allergy Immunology Unit, Department of Pediatrics.

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http://dx.doi.org/10.1097/RHU.0000000000001002DOI Listing
March 2019
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Healing of Mucocutaneous Lesions With Apremilast in Behçet Disease.

J Clin Rheumatol 2019 Mar 20. Epub 2019 Mar 20.

Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1097/RHU.0000000000001005DOI Listing
March 2019
1 Read