1,894 results match your criteria Clinical Research in Cardiology[Journal]


Atrial high rate episodes in patients with cardiac implantable electronic devices: implications for clinical outcomes.

Clin Res Cardiol 2019 Feb 13. Epub 2019 Feb 13.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.

Background: Atrial high rate episodes (AHREs) detected by cardiac implantable electronic devices (CIEDs) are associated with an increased risk of stroke. However, the impact of AHRE on improving stroke risk stratification scheme remains uncertain.

Objective: The purpose of this study was to assess the impact of AHRE on prognosis in relation with cardiovascular events and risk stratification. Read More

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http://dx.doi.org/10.1007/s00392-019-01432-yDOI Listing
February 2019

Severe eosinophilic myocarditis associated with modafinil in a patient with normal peripheral eosinophil count.

Clin Res Cardiol 2019 Feb 12. Epub 2019 Feb 12.

Department of Medicine III (Interdisciplinary Medical Intensive Care), Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1007/s00392-019-01434-wDOI Listing
February 2019

Prognostic impact of recurrences of ventricular tachyarrhythmias and appropriate ICD therapies in a high-risk ICD population.

Clin Res Cardiol 2019 Feb 12. Epub 2019 Feb 12.

First Department of Medicine, Faculty of Medicine Mannheim, European Center for AngioScience (ECAS), and DZHK, University Medical Centre Mannheim (UMM), University of Heidelberg, German Center for Cardiovascular Research) partner site Heidelberg/Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Purpose: The study sought to evaluate the prognostic impact of recurrences of ventricular tachyarrhythmias in consecutive ICD recipients with ventricular tachyarrhythmias on admission.

Methods: All consecutive patients surviving at least one episode of ventricular tachyarrhythmias from 2002 to 2016 and discharged with an ICD (pre-existing ICD or ICD implantation at index hospitalization) were included. The primary endpoint was all-cause mortality according to the presence or absence of recurrences of ventricular tachyarrhythmias at 5 years. Read More

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http://dx.doi.org/10.1007/s00392-019-01416-yDOI Listing
February 2019

Transcatheter aortic valve replacement for pure aortic valve regurgitation: "on-label" versus "off-label" use of TAVR devices.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Department of Cardiology, University Heart Center Berlin and Charité University Medicine Berlin, Campus Benjamin-Franklin, Berlin, Germany.

Introduction: Transcatheter aortic valve replacement (TAVR) has become the mainstay of treatment for aortic stenosis in patients with high surgical risk. Pure aortic regurgitation (PAR) is considered a relative contraindication for TAVR; however, TAVR is increasingly performed in PAR patients with unfavorable risk profile. Herein, we aim to summarize available data on TAVR for PAR with special emphasis on "on-label" versus "off-label" TAVR devices. Read More

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http://dx.doi.org/10.1007/s00392-019-01422-0DOI Listing
February 2019
1 Read

Association between atrial fibrillation and Helicobacter pylori.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Department of Cardiothoracic Surgery, Cardiovascular Research Institute Maastricht -CARIM, Maastricht University Medical Centre, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

The connection between atrial fibrillation (AF) and H. pylori (HP) infection is still matter of debate. We performed a systematic review and metanalysis of studies reporting the association between AF and HF. Read More

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http://dx.doi.org/10.1007/s00392-019-01418-wDOI Listing
February 2019
1 Read

Hemodynamics of paradoxical severe aortic stenosis: insight from a pressure-volume loop analysis.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Cardiovascular Center, St. Josef Hospital Bochum, Ruhr-University Bochum, Gudrunstraße 56, 44791, Bochum, Germany.

Background: Controversy exists about the pathophysiology of different hemodynamic subgroups of AS. In particular, the mechanism of the paradoxical low-flow, low-gradient (PLFLG) AS with preserved ejection fraction (EF) is unclear.

Methods: A total of 41 patients with severe, symptomatic AS were divided into the following 4 subgroups based on the echocardiographically determined hemodynamics: (1) normal-flow, high-gradient (NFHG) AS; (2) low-flow, high-gradient AS; (3) paradoxical low-flow, low-gradient (PLFLG) AS with preserved EF and (4) low-flow, low-gradient (LFLG) AS with reduced EF. Read More

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http://dx.doi.org/10.1007/s00392-019-01423-zDOI Listing
February 2019
4.560 Impact Factor

Percutaneous closure of a large atrial septal defect presenting with acute severe hemolysis.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

1Department of Cardiovasology, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

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http://dx.doi.org/10.1007/s00392-019-01431-zDOI Listing
February 2019

Retrieval of an embolised occluder with an alligator forceps during staged paravalvular leakage closure.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Herzzentrum Leipzig, Universitätsklinik für Kinderkardiologie, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00392-019-01419-9DOI Listing
February 2019

Impacts of non-recovery of trastuzumab-induced cardiomyopathy on clinical outcomes in patients with breast cancer.

Clin Res Cardiol 2019 Feb 8. Epub 2019 Feb 8.

Department of Cardiovascular Medicine, Chonnam National University Hospital, Gwangju, South Korea.

Objectives: The impacts of non-recovery of trastuzumab-induced left ventricular dysfunction (LVD) on clinical outcomes in breast cancer have been poorly studied. We investigated the predictors of LV-functional non-recovery and its impacts on clinical outcomes in breast cancer patients with trastuzumab-induced LVD.

Methods And Results: A total of 243 patients with trastuzumab-induced LVD were divided into the recovered LVD group (n = 195) and non-recovered LVD group (n = 48). Read More

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http://dx.doi.org/10.1007/s00392-019-01417-xDOI Listing
February 2019
4.560 Impact Factor

Impact of single-visit American versus European office blood pressure measurement procedure on individual blood pressure classification: a cross-sectional study.

Clin Res Cardiol 2019 Feb 6. Epub 2019 Feb 6.

Medical Outpatient Department, ESH Hypertension Center of Excellence, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.

Objectives: Recently, ACC/AHA and ESC/ESH guidelines defined different office blood pressure measurement (OBPM) procedures and ranges. We aimed to describe the effect of the different methods to calculate OBPM on BP classification.

Methods And Results: Four standardised OBPM were performed in 802 patients within a single visit. Read More

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http://dx.doi.org/10.1007/s00392-019-01426-wDOI Listing
February 2019
1 Read

Haemodynamic prosthetic valve performance in patients with early leaflet thrombosis after transcatheter aortic valve implantation.

Clin Res Cardiol 2019 Feb 6. Epub 2019 Feb 6.

Department of Cardiology and Angiology II, University Heart Center Freiburg-Bad Krozingen, Suedring 15, 79189, Bad Krozingen, Germany.

Aims: We sought to evaluate haemodynamic prosthetic valve performance in patients with early leaflet thrombosis (LT) after transcatheter aortic valve implantation (TAVI).

Method And Results: In this retrospective observational study, 59 patients with LT underwent clinical and echocardiographic follow-up. During a median follow-up of 383 days 41 patients received antiplatelet therapy (APT-group) and 18 patients oral anticoagulation due to atrial fibrillation (AC-group). Read More

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http://dx.doi.org/10.1007/s00392-019-01429-7DOI Listing
February 2019
1 Read

Left atrial anterior line ablation using ablation index and inter-lesion distance measurement.

Clin Res Cardiol 2019 Feb 2. Epub 2019 Feb 2.

Department of Cardiology, Asklepios Klinik - St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.

Background: Ablation index (AI) is a novel ablation quality marker that incorporates contact force (CF), time and power in a weighted formula to provide accurate information about lesion formation during catheter ablation. This index has been evaluated for pulmonary vein isolation (PVI) but has not been systematically used for other left atrial (LA) procedures so far. The aim of this study is to evaluate the feasibility and efficacy of this index for LA anterior line (AL) ablation (LAALA). Read More

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http://link.springer.com/10.1007/s00392-019-01428-8
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http://dx.doi.org/10.1007/s00392-019-01428-8DOI Listing
February 2019
3 Reads

Polyhedral erythrocytes in intracoronary thrombus and their association with reperfusion in myocardial infarction.

Clin Res Cardiol 2019 Feb 1. Epub 2019 Feb 1.

Department of Experimental Cardiac Surgery, Anesthesiology and Cardiology, Jagiellonian University Medical College, 80 Pradnicka Street, 31-202, Krakow, Poland.

Objective: The tightly packed arrays of polyhedral erythrocytes, polyhedrocytes, formed during thrombus contraction, have been detected in some intracoronary thrombi (ICT) obtained from patients with ST-segment elevation myocardial infarction (STEMI). We sought to investigate determinants of polyhedrocyte content in ICT and its association with reperfusion in STEMI.

Methods: We assessed the composition of ICT obtained during thrombectomy within 12 h since the symptom onset in 110 STEMI patients, following 300 mg of aspirin (n = 110) and 600 mg of clopidogrel (n = 75). Read More

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http://link.springer.com/10.1007/s00392-019-01425-x
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http://dx.doi.org/10.1007/s00392-019-01425-xDOI Listing
February 2019
1 Read

Stress T1-mapping cardiovascular magnetic resonance imaging and inducible myocardial ischemia.

Clin Res Cardiol 2019 Jan 30. Epub 2019 Jan 30.

General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg, 20246, Germany.

Background: Alterations in native myocardial T1 under vasodilation stress ("T1 reactivity") were recently proposed as a non-contrast cardiovascular magnetic resonance (CMR) method to detect myocardial ischemia. This study evaluated the performance of a segmental, truly non-contrast stress T1 mapping CMR approach to detect inducible ischemia.

Methods And Results: One-hundred patients with suspected/known coronary artery disease underwent CMR at 3. Read More

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http://dx.doi.org/10.1007/s00392-019-01421-1DOI Listing
January 2019

Efficacy of an implantable cardioverter-defibrillator in patients with diabetes and heart failure and reduced ejection fraction.

Clin Res Cardiol 2019 Jan 28. Epub 2019 Jan 28.

British Heart Foundation Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.

Background: The effect of implantable cardioverter-defibrillator (ICD) therapy in patients with heart failure with reduced ejection fraction (HFrEF) and diabetes is not fully elucidated.

Methods: We examined the effect of ICD therapy on sudden cardiac death, cardiovascular death and all-cause mortality, according to diabetes status at baseline in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT). The outcomes were analyzed by use of cumulative incidence curves and Cox regressions models. Read More

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http://dx.doi.org/10.1007/s00392-019-01415-zDOI Listing
January 2019

Prognostic significance of changes in heart rate following uptitration of beta-blockers in patients with sub-optimally treated heart failure with reduced ejection fraction in sinus rhythm versus atrial fibrillation.

Clin Res Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Division of Molecular and Clinical Medicine, Medical Research Institute, Mailbox 2, Ninewells Hospital & Medical School, University of Dundee, Dundee, DD1 9SY, UK.

Background: In patients with heart failure with reduced ejection fraction (HFrEF) on sub-optimal doses of beta-blockers, it is conceivable that changes in heart rate following treatment intensification might be important regardless of underlying heart rhythm. We aimed to compare the prognostic significance of both achieved heart rate and change in heart rate following beta-blocker uptitration in patients with HFrEF either in sinus rhythm (SR) or atrial fibrillation (AF).

Methods: We performed a post hoc analysis of the BIOSTAT-CHF study. Read More

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http://link.springer.com/10.1007/s00392-018-1409-x
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http://dx.doi.org/10.1007/s00392-018-1409-xDOI Listing
January 2019
2 Reads
4.560 Impact Factor

Incidence, predictors, and outcomes of DAPT disruption due to non-compliance vs. bleeding after PCI: insights from the PARIS Registry.

Clin Res Cardiol 2019 Jan 3. Epub 2019 Jan 3.

The Zena and Michael A. Wiener Cardiovascular Institute, The Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

Background: The disruption of dual antiplatelet therapy (DAPT) due to non-compliance or bleeding is known to significantly increase the risk of adverse outcomes after percutaneous coronary intervention (PCI). However, it is currently unknown if there are differences in the predictors and clinical impact of disruption due to non-compliance compared with bleeding.

Methods: The patterns of non-adherence to antiplatelet regimens in stented patients (PARIS) registry was an international, multicenter prospective study of PCI patients discharged on DAPT (aspirin + a P2Y receptor). Read More

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http://dx.doi.org/10.1007/s00392-018-1392-2DOI Listing
January 2019
2 Reads
4.560 Impact Factor

Impact of eplerenone on major cardiovascular outcomes in patients with systolic heart failure according to baseline heart rate.

Clin Res Cardiol 2019 Jan 2. Epub 2019 Jan 2.

Department of Epidemiology and Preventive Medicine, CCRE Therapeutics, Monash University/Alfred Hospital, 553 St Kilda Rd, Melbourne, VIC, 3004, Australia.

Background: Increased resting heart rate is a risk factor for cardiovascular mortality and morbidity. Mineralocorticoid receptor antagonists (MRAs) have been shown to improve cardiac sympathetic nerve activity, reduce heart rate and attenuate left ventricular remodelling. Whether or not the beneficial effects of MRA are affected by heart rate in heart failure patients with reduced ejection fraction (HFREF) is unclear. Read More

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http://dx.doi.org/10.1007/s00392-018-1410-4DOI Listing
January 2019
2 Reads

Direct oral anticoagulants and vitamin K antagonists are linked to differential profiles of cardiac function and lipid metabolism.

Clin Res Cardiol 2019 Jan 2. Epub 2019 Jan 2.

Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

Background: Experimental data indicate that direct acting oral anticoagulants (DOAC) and vitamin K antagonists (VKA) may exert differential effects on cardiovascular disease.

Methods: Data from the prospective, observational, single-center MyoVasc Study were used to examine associations of DOAC as compared to VKA with subclinical markers of cardiovascular disease, cardiac function, and humoral biomarkers in heart failure (HF).

Results: Multivariable analysis adjusted for age, sex, traditional cardiovascular risk factors, comorbidities, and medications with correction for multiple testing demonstrated that DOAC therapy was among all investigated parameters an independent significant predictor of better diastolic function (E/E': β - 0. Read More

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http://dx.doi.org/10.1007/s00392-018-1408-yDOI Listing
January 2019
2 Reads

Prognostic impact of chronic kidney disease and renal replacement therapy in ventricular tachyarrhythmias and aborted cardiac arrest.

Clin Res Cardiol 2018 Dec 21. Epub 2018 Dec 21.

First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), University of Heidelberg, European Center for AngioScience (ECAS), and DZHK (German Center for Cardiovascular Research) Partner Site Heidelberg/Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

Background: The study sought to assess the prognostic impact of chronic kidney disease (CKD) and renal replacement therapy (RRT) in patients with ventricular tachyarrhythmias and sudden cardiac arrest (SCA) on admission.

Methods: A large retrospective registry was used including all consecutive patients presenting with ventricular tachycardia (VT), fibrillation (VF) and SCA on admission from 2002 to 2016. Non-CKD vs. Read More

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http://dx.doi.org/10.1007/s00392-018-1396-yDOI Listing
December 2018
3 Reads
4.560 Impact Factor

Incomplete echocardiographic recovery at 6 months predicts long-term sequelae after intermediate-risk pulmonary embolism. A post-hoc analysis of the Pulmonary Embolism Thrombolysis (PEITHO) trial.

Clin Res Cardiol 2018 Dec 18. Epub 2018 Dec 18.

Center for Thrombosis and Hemostasis, University Medical Center, Langenbeckstrasse 1, Mainz, Germany.

Introduction: Symptoms and functional limitation are frequently reported by survivors of acute pulmonary embolism (PE). However, current guidelines provide no specific recommendations on which patients should be followed after acute PE, when follow-up should be performed, and which tests it should include. Definition and classification of late PE sequelae are evolving, and their predictors remain to be determined. Read More

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http://dx.doi.org/10.1007/s00392-018-1405-1DOI Listing
December 2018
4 Reads
4.560 Impact Factor

Transaxillary transcatheter aortic valve implantation utilizing a novel vascular closure device with resorbable collagen material: a feasibility study.

Clin Res Cardiol 2018 Dec 17. Epub 2018 Dec 17.

Department of General and Interventional Cardiology, University Heart Center Hamburg, Martinistrasse 52, 20246, Hamburg, Germany.

Objectives: We herein aimed to evaluate technical feasibility of transaxillary (Tax) transcatheter aortic valve implantation (TAVI) utilizing a novel vascular closure device with a resorbable collagen plug and absence of suture material.

Methods: Between 05/2018 and 8/2018, eight patients (76.0 ± 5. Read More

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http://dx.doi.org/10.1007/s00392-018-1407-zDOI Listing
December 2018
4 Reads

Malignant anomalous origin of circumflex artery in an elite athlete.

Clin Res Cardiol 2018 Dec 17. Epub 2018 Dec 17.

Department of Cardiology and Angiology, University Hospital Giessen, Klinikstraße 33, 35390, Giessen, Germany.

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http://dx.doi.org/10.1007/s00392-018-1406-0DOI Listing
December 2018
2 Reads

Characteristics and outcomes of patients ≤ 75 years who underwent transcatheter aortic valve implantation: insights from the SOURCE 3 Registry.

Clin Res Cardiol 2018 Dec 14. Epub 2018 Dec 14.

Division of Adult Congenital and Valvular Heart Disease, Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany.

Background: Current trials and registries of transcatheter valve implantation (TAVI) mostly include patients older than 75 years. Little is known about younger patients who undergo this treatment. We investigated comorbidities among patients < 75 years old who underwent TAVI in the SAPIEN 3™ European post-approval SOURCE 3 Registry, and analysed outcomes at 30 days and 1 year. Read More

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http://dx.doi.org/10.1007/s00392-018-1404-2DOI Listing
December 2018
4 Reads

Contrast-free, echocardiography-guided left atrial appendage occlusion (LAAo): a propensity-matched comparison with conventional LAAo using the AMPLATZER™ Amulet™ device.

Clin Res Cardiol 2018 Dec 10. Epub 2018 Dec 10.

Med. Klinik und Poliklinik II-Herzzentrum Bonn, Universitätsklinikum Bonn, Bonn, Germany.

Aims: Percutaneous left atrial appendage occlusion (LAAo) is commonly performed under fluoroscopy including the use of contrast dye. In this study, we aimed to assess feasibility and safety of contrast-free, 3D-echo-based LAAo with the use of the AMPLATZER™ Amulet™ device.

Methods And Results: We analyzed 20 patients (74 ± 10 years, 65% males) at an increased thromboembolic and bleeding risk (CHADSVASC 4. Read More

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http://dx.doi.org/10.1007/s00392-018-1401-5DOI Listing
December 2018
4 Reads

Left atrial strain improves estimation of filling pressures in heart failure: a simultaneous echocardiographic and invasive haemodynamic study.

Clin Res Cardiol 2018 Dec 10. Epub 2018 Dec 10.

Institution for Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.

Aims: Left ventricular diastolic pressure estimation is essential for characterization of heart failure (HF). Patients with normal resting left atrial (LA) pressures (LAP), but steep LAP elevation on exertion, pose a particular diagnostic challenge. Current recommendations on echocardiographic LAP estimation have limited accuracy. Read More

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http://link.springer.com/10.1007/s00392-018-1399-8
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http://dx.doi.org/10.1007/s00392-018-1399-8DOI Listing
December 2018
9 Reads

Variations on classification of main types of myocardial infarction: a systematic review and outcome meta-analysis.

Clin Res Cardiol 2018 Dec 7. Epub 2018 Dec 7.

3rd Department of Medicine, Cardiology and Intensive Care Medicine, Wilhelminen Hospital, Vienna, Austria.

Objective: Classifying myocardial infarction into type 1 (T1MI) or type 2 (T2MI) remains a challenge in clinical practice. We aimed to identify factors contributing to variation in the classifications of MI into type 1 or type 2. In addition, pooled analyses of long-term mortality and reinfarction outcomes were performed. Read More

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http://link.springer.com/10.1007/s00392-018-1403-3
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http://dx.doi.org/10.1007/s00392-018-1403-3DOI Listing
December 2018
3 Reads

Cardiac melanoma metastases as a cause of sudden cardiac death.

Clin Res Cardiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Cardiology, Heart Center Leipzig at University of Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00392-018-1402-4DOI Listing
December 2018
3 Reads

Catheter ablation in ASymptomatic PEDiatric patients with ventricular preexcitation: results from the multicenter "CASPED" study.

Clin Res Cardiol 2018 Dec 5. Epub 2018 Dec 5.

Department of Electrophysiology, German Heart Center Munich, Munich, Germany.

Background: As there are limited data about the clinical practice of catheter ablation in asymptomatic children and adolescents with ventricular preexcitation on ECG, we performed the multicenter "CASPED" (Catheter ablation in ASymptomatic PEDiatric patients with Ventricular Preexcitation) study.

Methods And Results: In 182 consecutive children and adolescents aged between 8 and 18 years (mean age 12.9 ± 2. Read More

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http://link.springer.com/10.1007/s00392-018-1397-x
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http://dx.doi.org/10.1007/s00392-018-1397-xDOI Listing
December 2018
12 Reads

MicroRNA-214 promotes the calcification of human aortic valve interstitial cells through the acceleration of inflammatory reactions with activated MyD88/NF-κB signaling.

Clin Res Cardiol 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Affiliated Hospital of Nantong University, No. 20, Xisi Road, Chongchuan District, Nantong, 226001, Jiangsu, China.

Calcific aortic valve disease (CAVD) is a complex active process involving in endothelial injury, lipid infiltration, chronic inflammation, matrix remodeling, cell differentiation, progressive bone formation, and new angiogenesis. The excess inflammatory responses induced by aortic valve interstitial cells (AVICs) are one of the common pathogeneses of this disease. Although many microRNAs (miRs) have been identified to play crucial roles in the calcification process of the aortic valve, numerous miRs are still waiting to be explored. Read More

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http://link.springer.com/10.1007/s00392-018-1398-9
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http://dx.doi.org/10.1007/s00392-018-1398-9DOI Listing
December 2018
11 Reads

The impact of biventricular heart failure on outcomes after transcatheter aortic valve implantation.

Clin Res Cardiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Cardiology, Asklepios Klinik St. Georg, Lohmühlenstr. 5, 20099, Hamburg, Germany.

Aims: We sought to assess the impact of different manifestations of heart failure (HF) at baseline on the short- and long-term outcomes of transcatheter aortic valve implantation (TAVI) for aortic stenosis (AS).

Methods And Results: Of 361 patients undergoing TAVI between May 2013 and April 2015, 185 (51%) showed clinical signs of HF at the time of admission. HF was diagnosed as isolated left ventricular (LV) and biventricular in 63 (34%) and 122 patients (66%), respectively. Read More

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http://dx.doi.org/10.1007/s00392-018-1400-6DOI Listing
December 2018
1 Read

Secondary rise in blood pressure and leg swelling after central arteriovenous anastomosis.

Clin Res Cardiol 2018 Nov 23. Epub 2018 Nov 23.

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66421, Homburg, Sarr, Germany.

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http://dx.doi.org/10.1007/s00392-018-1395-zDOI Listing
November 2018
12 Reads

The incidence, indications and predictors of acute pacemaker implantation after ablation of persistent atrial fibrillation.

Clin Res Cardiol 2018 Nov 20. Epub 2018 Nov 20.

Klinik für Herz-und Kreislauferkrankungen, Abteilung Elektrophysiologie, Deutsches Herzzentrum München, Technische Universität München, Lazarettstr. 36, 80636, Munich, Germany.

Introduction: Patients with persistent atrial fibrillation (AF) may additionally suffer from a concealed sinus node disease. We sought to determine the incidence, indications and predictors of acute pacemaker [PM] implantation within 1 week after the ablation of persistent AF.

Methods And Results: We performed a retrospective analysis of patients, who had had an ablation of persistent AF at our center. Read More

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http://link.springer.com/10.1007/s00392-018-1393-1
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http://dx.doi.org/10.1007/s00392-018-1393-1DOI Listing
November 2018
4 Reads

Incidence and impact of prosthesis-patient mismatch following transcatheter aortic valve implantation.

Clin Res Cardiol 2018 Nov 19. Epub 2018 Nov 19.

Department of Internal Medicine III, Cardiology and Angiology, University Hospital Schleswig-Holstein, Kiel, Germany.

Introduction: The implications of prosthesis-patient mismatch (PPM) in the context of transcatheter aortic valve implantation (TAVI) are still controversial. The objective of our study was thus to investigate the incidence and prognostic impact of PPM after TAVI.

Methods: Our analysis included 613 TAVI patients in whom the indexed effective orifice area (iEOA) after TAVI was obtained in vivo using echocardiography. Read More

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http://link.springer.com/10.1007/s00392-018-1394-0
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http://dx.doi.org/10.1007/s00392-018-1394-0DOI Listing
November 2018
18 Reads

The role of atrial fibrillation in the short-term outcomes of patients with acute heart failure.

Clin Res Cardiol 2018 Nov 13. Epub 2018 Nov 13.

Emergency Department, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

Aims: To investigate whether the presence of atrial fibrillation (AF) is independently associated with adverse short-term outcomes in patients diagnosed with acute heart failure (AHF) in the emergency department (ED).

Methods: We performed a secondary analysis of patients included in the EAHFE registries 4&5. Patients were divided by the presence of sinus rhythm (SR) or AF at ED arrival. Read More

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http://link.springer.com/10.1007/s00392-018-1389-x
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http://dx.doi.org/10.1007/s00392-018-1389-xDOI Listing
November 2018
12 Reads

Atrial fibrillation reduction by renal sympathetic denervation: 12 months' results of the AFFORD study.

Clin Res Cardiol 2018 Nov 10. Epub 2018 Nov 10.

Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Room Rg6, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Aim: The purpose of this pilot study was to assess whether renal sympathetic denervation (RDN) decreases atrial fibrillation (AF) burden in hypertensive patients with symptomatic AF at 6- and 12-month follow-up, as measured using an implantable cardiac monitor (ICM).

Methods And Results: A total of 20 patients with symptomatic paroxysmal or persistent AF (EHRA ≥ II) and primary hypertension with a mean office systolic blood pressure (BP) of > 140 mmHg were enrolled. After enrolment, an ICM was implanted 3 months pre-RDN to monitor AF burden. Read More

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http://dx.doi.org/10.1007/s00392-018-1391-3DOI Listing
November 2018
4 Reads

Correction to: Prognostic value of estimated plasma volume in acute heart failure in three cohort studies.

Clin Res Cardiol 2018 Nov 6. Epub 2018 Nov 6.

INSERM, Centre d'Investigations Cliniques 1433, Centre d'Investigation Clinique Pierre Drouin, CHRU de Nancy, Inserm 1116 and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN Network, Institut lorrain du coeur et des, vaisseaux Louis Mathieu, Université de Lorraine, 4, rue du Morvan, 54500, Nancy, Vandoeuvre-Les-Nancy, France.

Unfortunately, an error occurred in the methods section of the abstract. Read More

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http://link.springer.com/10.1007/s00392-018-1390-4
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http://dx.doi.org/10.1007/s00392-018-1390-4DOI Listing
November 2018
17 Reads

Interventional closure vs. medical therapy of patent foramen ovale for secondary prevention of stroke: updated meta-analysis.

Authors:
Syed Raza Shah

Clin Res Cardiol 2018 Oct 29. Epub 2018 Oct 29.

North Florida Regional Medical Center, University of Central Florida (Gainesville), 6500 West Newberry Road, Gainesville, FL, 32605, USA.

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http://link.springer.com/10.1007/s00392-018-1382-4
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http://dx.doi.org/10.1007/s00392-018-1382-4DOI Listing
October 2018
18 Reads

Personalized approach as the best treatment strategy in patients after cryptogenic stroke and PFO.

Clin Res Cardiol 2018 Oct 29. Epub 2018 Oct 29.

Klinik für Innere Medizin III, Universität des Saarlandes, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00392-018-1383-3DOI Listing
October 2018
1 Read

Diagnostic and prognostic value of plasma volume status at emergency department admission in dyspneic patients: results from the PARADISE cohort.

Clin Res Cardiol 2018 Oct 28. Epub 2018 Oct 28.

INSERM, Centre d'Investigations Cliniques Plurithématique 1433, Institut Lorrain du Coeur et des Vaisseaux, Vandoeuvre les Nancy, France.

Background: Systemic congestion, evaluated by estimated plasma volume status (ePVS), is associated with in-hospital mortality in acute heart failure (AHF). However, the diagnostic and prognostic value of ePVS in patients with acute dyspnea has been insufficiently studied.

Objectives: To assess the association between the first ePVS calculated from blood samples on admission in the emergency department (ED) and discharge diagnosis of AHF and in-hospital mortality in patients admitted for acute dyspnea. Read More

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http://link.springer.com/10.1007/s00392-018-1388-y
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http://dx.doi.org/10.1007/s00392-018-1388-yDOI Listing
October 2018
12 Reads

Test-retest reliability of new and conventional echocardiographic parameters of left ventricular systolic function.

Clin Res Cardiol 2018 Oct 27. Epub 2018 Oct 27.

Department of Medical Sciences, Cardiology and Clinical Physiology, Uppsala University, Uppsala, Sweden.

Background: Reliability of left ventricular function measurements depends on actual biological conditions, repeated registrations and their analyses.

Objective: To investigate test-retest reliability of speckle-tracking-derived strain measurements and its determinants compared to the conventional parameters, such as ejection fraction (EF), LV volumes and mitral annular plane systolic excursion (MAPSE).

Methods: In 30 patients with a wide range of left ventricular function (mean EF 46. Read More

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http://dx.doi.org/10.1007/s00392-018-1363-7DOI Listing
October 2018
1 Read

Plasma interleukin 6 levels are associated with cardiac function after ST-elevation myocardial infarction.

Clin Res Cardiol 2018 Oct 26. Epub 2018 Oct 26.

Department of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands.

Background And Aims: Myocardial infarction triggers an inflammatory response involved in cardiac repair. We studied the association of the interleukin 6 (IL-6) cascade with infarct size and cardiac function after ST-elevation myocardial infarction (STEMI).

Methods: In 369 STEMI patients IL-6, soluble IL-6 receptor (sIL-6R), and soluble glycoprotein (sgp) 130 were measured at baseline (hospital admission), 24 h, 2 weeks, 7 weeks, 4 months, and 1 year post-PCI and sIL-6R/IL-6 ratio was calculated. Read More

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http://link.springer.com/10.1007/s00392-018-1387-z
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http://dx.doi.org/10.1007/s00392-018-1387-zDOI Listing
October 2018
5 Reads

Recovery from left ventricular dysfunction was associated with the early introduction of heart failure medical treatment in cancer patients with anthracycline-induced cardiotoxicity.

Clin Res Cardiol 2018 Oct 26. Epub 2018 Oct 26.

Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.

Background: Left ventricular (LV) dysfunction due to anthracycline-induced cardiotoxicity (AIC) has been believed to be irreversible. However, this has not been confirmed and standard medical treatment for heart failure (HF) including renin-angiotensin inhibitors and β-blockers may lead to its recovery.

Methods And Results: We thus retrospectively studied 350 cancer patients receiving anthracycline-based chemotherapy from 2001 to 2015 in our institution. Read More

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http://dx.doi.org/10.1007/s00392-018-1386-0DOI Listing
October 2018
8 Reads

Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC.

Clin Res Cardiol 2018 Sep 4. Epub 2018 Sep 4.

Department of Internal Medicine/Cardiology, Heart Center Leipzig, University Hospital, Leipzig, Germany.

Extracorporeal cardiopulmonary resuscitation (eCPR) may be considered as a rescue attempt for highly selected patients with refractory cardiac arrest and potentially reversible aetiology. Currently, there are no randomised, controlled studies on eCPR. Thus, prospective validated predictors of benefit and outcome are lacking. Read More

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http://link.springer.com/10.1007/s00392-018-1366-4
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http://dx.doi.org/10.1007/s00392-018-1366-4DOI Listing
September 2018
12 Reads
4.560 Impact Factor

Mode of presentation and mortality amongst patients hospitalized with heart failure? A report from the First Euro Heart Failure Survey.

Clin Res Cardiol 2018 Oct 25. Epub 2018 Oct 25.

Robertson Centre for Biostatistics, University of Glasgow and National Heart and Lung Institute, Imperial College London, London, UK.

Background: Heart failure is heterogeneous in aetiology, pathophysiology, and presentation. Despite this diversity, clinical trials of patients hospitalized for HF deal with this problem as a single entity, which may be one reason for repeated failures.

Methods: The first EuroHeart Failure Survey screened consecutive deaths and discharges of patients with suspected heart failure during 2000-2001. Read More

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http://dx.doi.org/10.1007/s00392-018-1380-6DOI Listing
October 2018
2 Reads

Prognostic significance of ventricular tachycardia clustering after catheter ablation in non-ischemic dilated cardiomyopathy.

Clin Res Cardiol 2018 Oct 22. Epub 2018 Oct 22.

Department of Cardiology, Asklepios Klinik, St Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.

Background: Ventricular tachycardia clustering (VTc) is associated with a worse clinical outcome in patients with non-ischemic dilated cardiomyopathy (NI-DCM) and implantable cardioverter defibrillator (ICD); however, its role after catheter ablation (CA) has still not been investigated. Aim of this study was to evaluate the prognostic significance of VTc after CA.

Methods: 96 consecutive patients (59 ± 13 years, 82% males) with NI-DCM underwent CA for drug-refractory VT. Read More

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http://link.springer.com/10.1007/s00392-018-1384-2
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http://dx.doi.org/10.1007/s00392-018-1384-2DOI Listing
October 2018
12 Reads

Prognostic value of estimated plasma volume in acute heart failure in three cohort studies.

Clin Res Cardiol 2018 Oct 19. Epub 2018 Oct 19.

INSERM, Centre d'Investigations Cliniques 1433, Centre d'Investigation Clinique Pierre Drouin, CHRU de Nancy, Inserm 1116 and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN Network, Institut lorrain du coeur et des, vaisseaux Louis Mathieu, Université de Lorraine, 4, rue du Morvan, 54500, Nancy, Vandoeuvre-Les-Nancy, France.

Aims: Estimated plasma volume status (ePVS) predicts prognosis in patients with heart failure (HF). It remains unclear whether admission, discharge or change ePVS best predicts post-discharge outcome in patients with acute decompensated heart failure (ADHF).

Methods: We retrospectively analyzed three cohort studies: 383 patients admitted at the Tokyo Medical University hospital, 165 patients admitted at the Centro Hospitalar do Porto and 164 patients admitted at the Nancy University Hospital (ICALOR study). Read More

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http://link.springer.com/10.1007/s00392-018-1385-1
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http://dx.doi.org/10.1007/s00392-018-1385-1DOI Listing
October 2018
9 Reads

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management.

Clin Res Cardiol 2018 Oct 10. Epub 2018 Oct 10.

Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg-August University Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Cardiac arrhythmias remain a common challenge and are associated with significant morbidity and mortality. Effective and safe rhythm control strategies are a primary, yet unmet need in everyday clinical practice. Despite significant pharmacological and technological advances, including catheter ablation and device-based therapies, the development of more effective alternatives is of significant interest to increase quality of life and to reduce symptom burden, hospitalizations and mortality. Read More

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http://dx.doi.org/10.1007/s00392-018-1377-1DOI Listing
October 2018
3 Reads

Ezetimibe in high-risk, previously treated statin patients: a systematic review and network meta-analysis of lipid efficacy.

Clin Res Cardiol 2018 Oct 9. Epub 2018 Oct 9.

Merck & Co., Inc., Kenilworth, NJ, USA.

Purpose: While statins are used as first-line treatments for high-risk patients with hypercholesterolemia, statin monotherapy is often insufficient to achieve target low-density lipoprotein cholesterol (LDL-C) levels. Second-line treatment options include up-titration of statin dose, switching to a more potent statin, or combination therapy, e.g. Read More

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http://link.springer.com/10.1007/s00392-018-1379-z
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http://dx.doi.org/10.1007/s00392-018-1379-zDOI Listing
October 2018
3 Reads

Apolipoproteins A1, B, and apoB/apoA1 ratio are associated with first ST-segment elevation myocardial infarction but not with recurrent events during long-term follow-up.

Clin Res Cardiol 2018 Oct 8. Epub 2018 Oct 8.

Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, The Netherlands.

Introduction: The current way to assess the risk of cardiovascular disease (CVD) is to measure conventional lipid and lipoprotein cholesterol fractions. Despite the success of statin treatment, residual cardiovascular risk remains high. Therefore, the value of extensive serum apolipoprotein (apo) profiling to assess the risk of ST-segment elevation myocardial infarction (STEMI) and of major adverse cardiac events (MACE) in patients with STEMI was investigated in a case-control design. Read More

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http://link.springer.com/10.1007/s00392-018-1381-5
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http://dx.doi.org/10.1007/s00392-018-1381-5DOI Listing
October 2018
4 Reads