18 results match your criteria Clinical Pulmonary Medicine[Journal]

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Sarcoidosis-associated Pulmonary Hypertension: Pathophysiology, Diagnosis, and Treatment.

Clin Pulm Med 2018 Mar;25(2):52-60

University of Chicago, Section of Pulmonary and Critical Care Medicine.

Clinicians in pulmonary medicine frequently confront the challenge of screening, diagnosis and management of pulmonary hypertension (PH) in sarcoidosis patients who present with unexplained dyspnea. Sarcoidosis associated pulmonary hypertension (SAPH) is most prevalent in patients with pulmonary fibrosis, though it can be independent of airflow obstruction or restriction. SAPH independently associates with significantly increased mortality and decreased functional capacity, outcomes which can be mitigated by early detection and focused treatment. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168942PMC
March 2018
14 Reads

Readmissions Among Sepsis Survivors: Risk Factors and Prevention.

Clin Pulm Med 2018 May;25(3):79-83

Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina.

Hospital readmissions are common and result in increased mortality and cost while reducing quality of life. Readmission rates have been subjected to increasing scrutiny in recent years as part of a larger effort to improve the quality and value of healthcare in the United States. Emerging evidence suggests that sepsis survivors are at high risk for hospital readmission and experience readmission rates comparable to survivors of congestive heart failure, acute myocardial infarction, pneumonia, and chronic obstructive pulmonary disease, diseases whose readmission rates determine reimbursement penalties from the federal government. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141202PMC
May 2018
10 Reads

Systemic lupus erythematosus-associated diffuse alveolar hemorrhage: A case report and review of the literature.

Clin Pulm Med 2018 Sep;25(5):166-169

Northwestern University Feinberg School of Medicine, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Chicago, IL, 60611, USA.

Systemic lupus erythematosus is associated with numerous pleuropulmonary complications. Although uncommon, diffuse alveolar hemorrhage represents a life-threatening cause of acute respiratory failure among patients with lupus. Here, we present a 24-year-old woman with a history of lupus who developed hemoptysis and respiratory failure associated with diffuse radiographic infiltrates and anemia. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136257PMC
September 2018
1 Read

Interstitial Pneumonia with Autoimmune Features: Overview of proposed criteria and recent cohort characterization.

Clin Pulm Med 2017 Sep;24(5):191-196

Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of California, Davis, Sacramento, CA.

The accurate diagnosis of interstitial lung disease (ILD) is essential for optimal prognostication and management. While connective tissue disease (CTD) is among the most common causes of ILD, some patients have features suggestive of autoimmunity without meeting criteria for a specific CTD. To help define and study this disease entity more uniformly, a 2015 research statement proposed consensus-based criteria and coined the term "interstitial pneumonia with autoimmune features" (IPAF). Read More

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http://dx.doi.org/10.1097/CPM.0000000000000227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739083PMC
September 2017
10 Reads

Precision-guided, Personalized Intrapleural Fibrinolytic Therapy for Empyema and Complicated Parapneumonic Pleural Effusions: The Case for the Fibrinolytic Potential.

Clin Pulm Med 2017 Jul;24(4):163-169

Department of Cellular and Molecular Biology and Texas Lung Injury institute, The University of Texas Health Science Center.

Complicated pleural effusions and empyema with loculation and failed drainage are common clinical problems. In adults, intrapleural fibrinolytic therapy is commonly used with variable results and therapy remains empiric. Despite the intrapleural use of various plasminogen activators; fibrinolysins, for about sixty years, there is no clear consensus about which agent is most effective. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654485PMC
July 2017
45 Reads

The Diagnosis and Treatment of Antisynthetase Syndrome.

Clin Pulm Med 2016 Sep;23(5):218-226

Section of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Chicago Medicine, Chicago, IL 60637.

Anti-synthetase syndrome is an autoimmune condition, characterized by antibodies directed against an aminoacycl transfer RNA synthetase along with clinical features that can include interstitial lung disease, myositis, Raynaud's phenomenon, and arthritis. There is a higher prevalence and increased severity of interstitial lung disease in patients with anti-synthetase syndrome, as compared to dermatomyositis and polymyositis, inflammatory myopathies with which it may overlap phenotypically. Diagnosis is made by a multidisciplinary approach, synthesizing rheumatology and pulmonary evaluations, along with serologic, radiographic, and occasionally muscle and/or lung biopsy results. Read More

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http://pdfs.journals.lww.com/clinpulm/2016/09000/The_Diagnos
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http://dx.doi.org/10.1097/CPM.0000000000000171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006392PMC
September 2016
15 Reads

Understanding persistent bacterial lung infections: clinical implications informed by the biology of the microbiota and biofilms.

Clin Pulm Med 2016 Mar;23(2):57-66

Division of Pulmonary, Allergy, and Critical Care Medicine, University of Minnesota.

The infections found in chronic obstructive pulmonary disease, cystic fibrosis, and bronchiectasis share a number of clinical similarities, the most striking of which is bacterial persistence despite the use of antibiotics. These infections have been clinically described using culture-based methods usually performed on sputum samples, and treatment has been directed towards the bacteria found in this manner. Unfortunately the clinical response to antibiotics is frequently not predictable based on these cultures, and the role of these cultured organisms in disease progression has been debated. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798234PMC
March 2016
17 Reads

Refractory pulmonary sarcoidosis - proposal of a definition and recommendations for the diagnostic and therapeutic approach.

Clin Pulm Med 2016 Mar;23(2):67-75

Department of Rheumatology and Department of Pulmonary Medicine, University of Illinois Hospital and Health Science System, Chicago, IL, USA.

Patients with sarcoidosis undergo spontaneous remission or may be effectively controlled with glucocorticoids alone in many cases. Progressive and refractory pulmonary sarcoidoisis constitute more than 10% of patients seen at specialized centers. Pulmonary fibrosis and associated complications, such as infections and pulmonary hypertension are leading causes of mortality. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782965PMC
March 2016
21 Reads

Severe Asthma: The Evolution of Patient-directed Management.

Clin Pulm Med 2014 Jan;21(1):1-8

Department of Medicine, Division of Pulmonary & Critical Care Medicine, Jesse Brown VA Medical Center and Northwestern University Feinberg School of Medicine, Chicago, IL.

Severe asthma has been increasingly recognized as a heterogenous disease with varied clinical characteristics and pathophysiological processes. Patients with severe asthma suffer significant impairment in their daily life and impose a substantial burden on health care resources. The recent work of consortia groups has led to an improved definition of severe asthma as well as better characterization of the patients with severe disease. Read More

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http://dx.doi.org/10.1097/CPM.0000000000000013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286352PMC
January 2014
9 Reads

Familial Interstitial Pneumonia (FIP).

Clin Pulm Med 2014 May;21(3):120-127

Professor of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Medical Director, Lung Transplant Program, Vanderbilt University School of Medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263205PMC
May 2014
19 Reads

The Role of Gastroesophageal Reflux and Microaspiration in Idiopathic Pulmonary Fibrosis.

Authors:
Joyce S Lee

Clin Pulm Med 2014 Mar;21(2):81-85

Department of Medicine, University of California, San Francisco.

There has been controversy regarding the relationship between gastroesophageal reflux, microaspiration, and idiopathic pulmonary fibrosis (IPF). In the last decade, there is increasing evidence supporting a relationship between gastroesophageal reflux, microaspiration, and IPF. Specifically, gastroesophageal reflux is common in IPF, is often asymptomatic in this population, and may impact disease progression and the natural history of IPF. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979481PMC
March 2014
7 Reads

THE PARADOXICAL EFFECT ON PNEUMONIA OF CHRONIC INHALED CORTICOSTEROIDS.

Clin Pulm Med 2013 Jan;20(1)

University of Texas Health Science Center at San Antonio, San Antonio, TX ; Servei de Pneumologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Several studies have shown that the risk of pneumonia is increased in patients with Chronic Obstructive Pulmonary Disease (COPD) who are receiving chronic inhaled corticosteroids (ICS). The impact of ICS On pneumonia prognosis is controversial. Read More

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http://dx.doi.org/10.1097/CPM.0b013e31827a2a60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828120PMC
January 2013
9 Reads

Disparities in Asthma Care, Management, and Education Among Children With Asthma.

Clin Pulm Med 2013 Jul;20(4):172-177

Air Pollution and Respiratory Health Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA.

Health disparities are pervasive in the United States. Health and health care disparities are the differences or gaps in health (eg, life expectancy, morbidity, risk factors, and quality of life) and health care access and quality between segments of the United States population as related to race/ethnicity and socioeconomic status (eg, income, education). Multiple factors are associated with such disparities in asthma management and education. Read More

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http://dx.doi.org/10.1097/CPM.0b013e3182991146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999068PMC
July 2013
39 Reads

Risks of Transthoracic Needle Biopsy: How High?

Clin Pulm Med 2013 Jan;20(1):29-35

The Pulmonary Center, Boston University School of Medicine, Boston, MA (RSW); Center for Health Quality, Outcomes and Economic Research, ENRM VA Hospital, Bedford, MA (RSW); Department of Surgery, Tufts University Medical Center, Boston, MA (DCW); Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA (MKG).

Transthoracic needle lung biopsy is a commonly performed diagnostic procedure for pulmonary nodules and masses. To make an informed decision about whether to pursue this procedure, doctors and patients must be aware of the possible risks of the procedure. We performed a MEDLINE search, 2003-2012 to identify relevant English-language studies that included at least 100 subjects and reported data on complications of transthoracic needle lung biopsy performed within the last 10 years. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CPM.0b013e31827a30c1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601755PMC
January 2013
20 Reads

Mesothelioma - Update on Diagnostic Strategies.

Clin Pulm Med 2012 Nov;19(6):282-288

Department of Medicine, Division of Pulmonary & Critical Care Medicine, Jesse Brown VA Medical Center and Northwestern University Feinberg School of Medicine, 240 E. Huron, McGaw M-330, Chicago, IL 60611.

Malignant pleural mesothelioma (MPM) can be a challenging diagnosis for clinicians to make as it is often difficult to distinguish from benign asbestos pleural effusions and metastatic carcinomas. In this review, we present a case of MPM and discuss clinical manifestations, traditional diagnostic techniques, and the role of cytopathologic immunostains and serum biomarkers in the diagnosis of MPM. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CPM.0b013e318272ce61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536474PMC
November 2012
9 Reads

Developing a Rational Approach to Tobacco Use Treatment in Pulmonary Practice: A Review of the Biological Basis of Nicotine Addiction.

Clin Pulm Med 2012 Mar;19(2):53-61

Associate Professor of Medicine, Division of Pulmonary and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA.

The toll of tobacco use on a pulmonary practice is severe. Physicians, patients, and their families experience frustration, hopelessness and even anger when confronted with a seemingly irrational decision to keep smoking despite morbid lung disease. This paper examines the biological basis of this behavior and seeks to integrate this insight into a rational approach to the problem in practice. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CPM.0b013e318247cadaDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375065PMC
March 2012
12 Reads

Multidisciplinary Evaluation of Patients With Suspected Lung Cancer.

Clin Pulm Med 2010 Jan;17(1):35-41

University of Michigan, Department of Internal Medicine, Division of Pulmonary & Critical Care Medicine.

Lung cancer diagnosis and treatment has evolved to require the input and expertise of multiple diverse medical and surgical specialties. The approach to lung cancer patients requires the adherence to a few principles that include thorough use of staging modalities to assure the proper treatment for each patient, and an understanding of the limitations and advantages of each of these modalities. Evidence is continuing to emerge that supports the notion that diagnostic workup and treatment of lung cancer patients is best done within the context of a multidisciplinary team devoted to this purpose. Read More

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http://dx.doi.org/10.1097/CPM.0b013e3181c849feDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808634PMC
January 2010
7 Reads

Pulmonary Strongyloidiasis: The Varied Clinical Presentations.

Clin Pulm Med 2004 Jan;11(1):6-13

Division of Pulmonary and Critical Care, Cook County Hospital and Rush University Medical Center, Chicago, IL.

Strongyloides stercoralis is a unique parasite. It can complete its life cycle entirely within the human host. As a result, an autoinfection cycle is set up. Read More

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http://dx.doi.org/10.1097/01.cpm.0000107609.50629.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812430PMC
January 2004
22 Reads
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