4,529 results match your criteria Clinical Nutrition[Journal]


Higher dietary vitamin C intake is associated with a lower risk of gestational diabetes mellitus: A longitudinal cohort study.

Clin Nutr 2019 Feb 2. Epub 2019 Feb 2.

Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030, Hubei, China. Electronic address:

Background & Aims: Oxidative stress has been implicated in the pathogenesis of gestational diabetes mellitus (GDM). Vitamin C as natural antioxidant may help to increase the body's antioxidant capacity. The study is aimed to determine whether vitamin C intake during pregnancy is associated with lower risk of GDM. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.015DOI Listing
February 2019

Association of total cholesterol with severe acute pancreatitis: A U-shaped relationship.

Clin Nutr 2019 Jan 31. Epub 2019 Jan 31.

Department of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China. Electronic address:

Background & Aims: There is no consensus on relationship between total cholesterol levels and incidence of severe acute pancreatitis (SAP). The aim of this study was to investigate the relation between total cholesterol (TC) and the disease severity of acute pancreatitis.

Methods: We conducted a cross-sectional study on patients with acute pancreatitis between April 2012 and December 2015 in a university hospital. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.022DOI Listing
January 2019

Nutrition education in medical schools (NEMS). An ESPEN position paper.

Clin Nutr 2019 Feb 7. Epub 2019 Feb 7.

Department of Gastroenterology and Nutritional Support, Hopital Erasme and Institut Bordet, Free University of Brussels, Brussels, Belgium.

Background & Aims: Nutrition education is necessary in the training of healthcare professionals, including medical students. However, recent surveys showed that there is a high variability within Medical Schools in different countries. The aim of this ESPEN position paper is to identify a minimum curriculum knowledge in nutrition that serves to improve the training of the future doctors and how to solve the main barriers of its implementation in university centres. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.02.001DOI Listing
February 2019

Is dietary supplement use longitudinally associated with fatigue in stage I-III colorectal cancer survivors?

Clin Nutr 2019 Jan 29. Epub 2019 Jan 29.

Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, PO Box 616, 6200 MD, Maastricht, the Netherlands. Electronic address:

Background & Aims: Supplement use among colorectal cancer (CRC) survivors is common, yet evidence supporting its beneficial health effects is mostly lacking and cancer-specific lifestyle guidelines advise against the use of supplements. We aimed to describe the use of supplements by CRC survivors from diagnosis to 2 years post-treatment and investigate how overall supplement use is longitudinally associated with fatigue.

Methods: In a prospective cohort study of stage I-III CRC survivors (n = 325), information on supplement use was collected during repeated home visits at diagnosis and at 6 weeks, 6, 12, and 24 months post-treatment. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.037DOI Listing
January 2019

How to well use the predictive equations for resting energy expenditure.

Authors:
Simiao Tian

Clin Nutr 2019 Feb 1. Epub 2019 Feb 1.

Department of Scientific Research Project, Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.01.025DOI Listing
February 2019

Reply - Letter to the Editor - Impact of sarcopenic obesity on outcomes in patients undergoing living donor liver transplantation.

Clin Nutr 2019 Feb 1. Epub 2019 Feb 1.

Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.clnu.2019.01.024DOI Listing
February 2019

Associations of specific dietary protein with longitudinal insulin resistance, prediabetes and type 2 diabetes: The Rotterdam Study.

Clin Nutr 2019 Jan 31. Epub 2019 Jan 31.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, the Netherlands. Electronic address:

Background & Aims: High protein intake has been linked to increased type 2 diabetes (T2D) risk. However, if this association differs by protein from specific food sources, and if a habitual high protein intake affects insulin resistance and prediabetes risk are largely unknown. We aimed to investigate associations between protein intake from different food sources with longitudinal insulin resistance, and risk of prediabetes and T2D. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.021DOI Listing
January 2019

Impact of sarcopenic obesity on outcomes in patients undergoing living donor liver transplantation.

Clin Nutr 2019 Feb 1. Epub 2019 Feb 1.

Department of Thorasic Surgery, Health Science University, Sancaktepe Sehit Profesor İlhan Varank Training and Research Hospital, Istanbul, Turkey.

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http://dx.doi.org/10.1016/j.clnu.2019.01.026DOI Listing
February 2019

The inflammatory potential of diet is related to incident frailty and slow walking in older adults.

Clin Nutr 2019 Jan 24. Epub 2019 Jan 24.

CIBERESP and Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/Idipaz, Arzobispo Morcillo, 4, 28029, Madrid, Spain; IMDEA-Food Institute, CEI UAM+CSIC, Madrid, Spain.

Background: Certain foods and dietary patterns have been associated with both inflammation and frailty. As chronic inflammation may play a role in frailty and disability, we examined the association of the inflammatory potential of diet with these outcomes.

Methods: Data were taken from 1948 community-dwelling individuals ≥60 years old from the Seniors-ENRICA cohort, who were recruited in 2008-2010 and followed-up through 2012. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.013DOI Listing
January 2019

Impact of school-based nutrition and physical activity intervention on body mass index eight years after cessation of randomized controlled trial (AVall study).

Clin Nutr 2019 Jan 24. Epub 2019 Jan 24.

Internal Medicine Department, Granollers General Hospital, Granollers, Spain; Medicine Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Catalonia, Spain. Electronic address:

Background & Aims: The prevalence of obesity and overweight among children is increasing, representing a new and pressing societal problem. Excess weight in childhood is an independent risk factor for adult obesity. Although school-based interventions are generally considered effective in the short term, few studies analyze their longterm impact. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.029DOI Listing
January 2019

Haptoglobin phenotype influences the effectiveness of diet-induced weight loss in middle-age abdominally obese women with metabolic abnormalities.

Clin Nutr 2019 Jan 26. Epub 2019 Jan 26.

School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Metabolism and Obesity Sciences, College of Nutrition, Taipei Medical University, Taipei, Taiwan; Nutrition Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Chinese Taipei Society for the Study of Obesity, CTSSO, Taipei, Taiwan. Electronic address:

Background & Aims: Haptoglobin (Hp) is associated with risks of obesity and cardiometabolic dysfunction; however, the role of the Hp phenotype in diet-induced weight loss remains to be elucidated. This study investigated whether the Hp phenotype contributes to inter-individual variations in body weight reduction as well as changes in the metabolic profile.

Methods: Secondary data analysis from a randomized controlled trial. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.019DOI Listing
January 2019
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Malaria early in the first pregnancy: Potential impact of iron status.

Clin Nutr 2019 Jan 26. Epub 2019 Jan 26.

Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L35QA, England, UK; Institute of Infection and Global Health, University of Liverpool, UK; Global Child Health Group, Academic Medical Centre, University of Amsterdam, the Netherlands. Electronic address:

Background & Aims: Low iron stores may protect from malaria infection, therefore improving iron stores in early pregnancy in line with current recommendations could increase malaria susceptibility. To test this hypothesis we compared iron biomarkers and red cell indices in nulliparae and primigravidae who participated in a randomized controlled trial of long-term weekly iron supplementation.

Methods: Cross-sectional and longitudinal data analysis from a randomized controlled trial of long-term weekly iron supplementation in rural Burkina Faso. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.016DOI Listing
January 2019

Measuring body composition in the preterm infant: Evidence base and practicalities.

Clin Nutr 2019 Jan 12. Epub 2019 Jan 12.

Department of Neonatal Medicine, Princess Anne Hospital, University Hospital Southampton NHS Foundation Trust, UK; National Institute for Health Research, Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK. Electronic address:

Preterm birth and body composition have demonstrable effects on growth and later health outcomes. Preterm infants reach term equivalent age with a lower proportion of lean mass and higher body fat percentage than their term equivalent counterparts. Weight and length do not give an accurate assessment of body composition. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.033DOI Listing
January 2019

Gender influences physical activity changes during adolescence: The HELENA study.

Clin Nutr 2019 Jan 25. Epub 2019 Jan 25.

Univ. Lille, CHU Lille, LIRIC UMR 995 Inserm, Clinical Investigation Center, CIC-1403-Inserm-CHU, F-59000 Lille, France.

Background: We compared differences in physical activity (PA) between pre/mid-pubertal and post-pubertal participants according to gender.

Methods: The study included a total of 1842 healthy participants aged 12.5-17. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.027DOI Listing
January 2019

Association of flavonoids and flavonoid-rich foods with all-cause mortality: The Blue Mountains Eye Study.

Clin Nutr 2019 Jan 17. Epub 2019 Jan 17.

School of Biomedical Sciences, University of Western Australia, Royal Perth Hospital, Perth, Western Australia, Australia; School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia, Australia.

Background: Higher intakes of flavonoids provide health benefits, however, the importance of each flavonoid class and which population groups may receive the greatest protection from higher flavonoid intake warrants further investigation.

Objective: To explore the associations of flavonoid and flavonoid-rich wholefood intakes with all-cause mortality and the moderating effects of early mortality risk factors.

Design: The study included 2349 participants of The Blue Mountains Eye Study, with a mean ± SD age at baseline of 64. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.004DOI Listing
January 2019
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Interaction analysis of gene variants of TCF7L2 and body mass index and waist circumference on type 2 diabetes.

Clin Nutr 2019 Jan 24. Epub 2019 Jan 24.

Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.

Background & Aims: Type 2 diabetes (T2D) is a complex metabolic disease with numerous risk factors, including a growing number of genetic susceptibility variants. The TCF7L2 gene is closely associated with an increased risk of type 2 diabetes, but the association of TCF7L2 with weight-related traits in humans is unclear. The purpose of this study was to determine if TCF7L2 variants and body mass index/waist circumference (BMI/WC) act synergistically to influence the incidence of type 2 diabetes in a Chinese population. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614193003
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http://dx.doi.org/10.1016/j.clnu.2019.01.014DOI Listing
January 2019
2 Reads

ESPEN guideline on clinical nutrition in liver disease.

Clin Nutr 2019 Jan 16. Epub 2019 Jan 16.

Department for Clinical Nutrition, University of Hohenheim, Stuttgart, Germany.

This update of evidence-based guidelines (GL) aims to translate current evidence and expert opinion into recommendations for multidisciplinary teams responsible for the optimal nutritional and metabolic management of adult patients with liver disease. The GL was commissioned and financially supported by ESPEN. Members of the guideline group were selected by ESPEN. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.022DOI Listing
January 2019
30 Reads

Reference body mass index values and the prevalence of malnutrition according to the Global Leadership Initiative on Malnutrition criteria.

Clin Nutr 2019 Jan 23. Epub 2019 Jan 23.

Palliative Care Center, Aichi Medical University, Japan; Nutritional Therapy Support Center, Aichi Medical University Hospital, Japan.

Background & Aims: The Global Leadership Initiative on Malnutrition (GLIM) released new criteria for diagnosing and grading malnutrition. This study aimed to investigate the optimal reference values of body mass index (BMI) for discriminating severe malnutrition according to the GLIM criteria, as well as the prevalence of GLIM-defined malnutrition in the clinical setting.

Methods: This study included 6783 patients aged ≥40 years, who were admitted to an academic hospital. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.011DOI Listing
January 2019

Effects of dietary patterns and low protein intake on sarcopenia risk in the very old: The Newcastle 85+ study.

Clin Nutr 2019 Jan 21. Epub 2019 Jan 21.

Newcastle University Institute for Ageing, Newcastle Upon Tyne, United Kingdom; Institute of Health & Society, Newcastle University, Newcastle Upon Tyne, United Kingdom.

Background: Sarcopenia, a progressive age-related loss of skeletal muscle mass and strength, leads to disability, falls, and hospitalisation. Individual variation in sarcopenia onset may be partly explained by lifestyle factors such as physical activity and diet. Healthy dietary patterns (DPs) have been linked to better physical functioning in older adults, but their role in sarcopenia in the very old (aged ≥85) is unknown. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.009DOI Listing
January 2019

Efficacy and safety of oral and inhalation commercial beta-glucan products: Systematic review of randomized controlled trials.

Clin Nutr 2019 Jan 14. Epub 2019 Jan 14.

Center for Evidence-Based Medicine and Health Care, Catholic University of Croatia, Zagreb, Croatia. Electronic address:

Background & Aims: Beta-glucans are advertised as biologically active compounds, with various health claims. We aimed to summarize results about efficacy and safety of commercial oral and inhalation beta-glucan products on human health from randomized controlled trials (RCTs).

Methods: We conducted systematic review of RCTs. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.003DOI Listing
January 2019

Influence of nutrition support therapy on readmission among patients with acute heart failure in the intensive care unit: A single-center observational study.

Clin Nutr 2019 Jan 22. Epub 2019 Jan 22.

Department of Anesthesiology and Intensive Care Medicine, Kochi Medical School, Japan.

Background & Aims: The effect of nutrition support therapy on prevention of readmission among patients with acute heart failure (HF) in an intensive care unit (ICU) setting remains unclear. We hypothesized that nutrition support therapy might decrease the readmission rate among these patients. Thus, we conducted a single-center prospective observational study to verify this hypothesis. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.010DOI Listing
January 2019

Vitamin B complex supplementation as a homocysteine-lowering therapy for early stage diabetic nephropathy in pediatric patients with type 1 diabetes: A randomized controlled trial.

Clin Nutr 2019 Jan 17. Epub 2019 Jan 17.

Department of Clinical Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Background: Homocysteine levels are elevated in patients with type 1 diabetes mellitus (T1DM) and could induce renal injury. B vitamins have an important role in preventing microvascular complications of diabetes.

Aim: We performed a randomized-controlled trial of oral supplementation with vitamin B complex as an adjuvant therapy for nephropathy in pediatric T1DM patients and assessed its relation to homocysteine and cystatin C as a marker of nephropathy. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.006DOI Listing
January 2019
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Protein timing has no effect on lean mass, strength and functional capacity gains induced by resistance exercise in postmenopausal women: A randomized clinical trial.

Clin Nutr 2019 Jan 17. Epub 2019 Jan 17.

School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil. Electronic address:

Background & Aims: Short-term studies have shown that protein intake immediately post-exercise increases muscle protein synthesis. However, the effect of protein timing (comparing protein intake post-exercise vs. several hours after exercise) on lean mass and strength gains in long-term studies is still not fully elucidated. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.008DOI Listing
January 2019
1 Read

Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer.

Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Unit of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, Umeå, Sweden; Department of Biology and Biological Engineering, Division of Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden.

Background & Aims: Rye consumption has shown beneficial effects on prostate cancer tumors, as indicated by slower initial tumor growth in animal models and lowering of prostate-specific antigen (PSA) in humans. This study evaluated the effects of whole grain/bran rye consumption on low-grade inflammation and endothelial function biomarkers in men with prostate cancer.

Methods: Seventeen men with untreated, low-grade prostate cancer consumed 485 g rye whole grain and bran products (RP) per day or refined wheat products with added cellulose (WP) in a randomized crossover design. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.007DOI Listing
January 2019
4 Reads

Potentially modifiable determinants of malnutrition in older adults: A systematic review.

Clin Nutr 2018 Dec 11. Epub 2018 Dec 11.

Department of Biological Sciences, University of Limerick, Limerick, Ireland; Alimentary Pharmabiotic Centre Microbiome Irelan, University College Cork, Cork, Ireland; Health Research Institute, University of Limerick, Limerick, Ireland. Electronic address:

Background & Aims: Malnutrition in older adults results in significant personal, social, and economic burden. To combat this complex, multifactorial issue, evidence-based knowledge is needed on the modifiable determinants of malnutrition. Systematic reviews of prospective studies are lacking in this area; therefore, the aim of this systematic review was to investigate the modifiable determinants of malnutrition in older adults. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.007DOI Listing
December 2018
2 Reads

Acute intestinal failure: International multicenter point-of-prevalence study.

Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Department of Digestive System, Center for Chronic Intestinal Failure, St Orsola-Malpighi Hospital, University of Bologna, Via Massarenti, 9, 40138, Bologna, Italy. Electronic address:

Background & Aims: Intestinal failure (IF) is defined from a requirement or intravenous supplementation due to failing capacity to absorb nutrients and fluids. Acute IF is an acute, potentially reversible form of IF. We aimed to identify the prevalence, underlying causes and outcomes of acute IF. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.005DOI Listing
January 2019
3 Reads

Novel approaches for the assessment of relative body weight and body fat in diagnosis and treatment of anorexia nervosa: A cross-sectional study.

Clin Nutr 2019 Jan 10. Epub 2019 Jan 10.

Department of Immunology and Pathophysiology, Medical University of Graz, Otto Loewi Research Center, Heinrichstraße, Graz, Austria.

Background & Aims: Anorexia nervosa (AN) is a severe psychosomatic disease that seriously affects nutritional status. Therapeutic approaches primarily aim for rapid weight restoration by high caloric diets and activity restriction. This often promotes abdominal body fat gain, which potentially negatively influences the patient's compliance and increases the risk of relapse. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.031DOI Listing
January 2019
1 Read

Indirect calorimetry as point of care testing.

Clin Nutr 2019 Jan 4. Epub 2019 Jan 4.

Department of General Intensive Care, Rabin Medical Center, Petah Tikva and Sackler School of Medicine, Tel Aviv University, Israel.

Determining energy requirement is a fundamental of nutrition support. Indirect calorimetry (IC) has been long recognized as the gold standard for assessing basal or resting energy expenditure (REE). The measurement of REE is recommended particularly in the situation where adjustment of energy provision is critical. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.035DOI Listing
January 2019

Falls among older adults with sarcopenia dwelling in nursing home or community: A meta-analysis.

Clin Nutr 2019 Jan 8. Epub 2019 Jan 8.

The Third Affiliated Hospital of Guangzhou Medical University, Research Institute of Gynecology & Obstetrics, Guangzhou, China.

Objectives: To assess and quantify sarcopenia as a risk for falls among community-dwelling older people and nursing home older persons.

Methods: Prospective cohort studies that evaluated the association between sarcopenia and falls in older adults were identified via a systematic literature search of Medline (via Ovid), PubMed, EMBASE, and the Cochrane CENTRAL Library from database inception until October 15, 2018, in English and Chinese.

Results: 10 studies (10,073 participants) were included in the meta-analysis. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.002DOI Listing
January 2019

Association between plasma concentration of copper and gestational diabetes mellitus.

Clin Nutr 2019 Jan 3. Epub 2019 Jan 3.

Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China. Electronic address:

Background & Aims: Emerging findings have raised concerns about significant associations between excessive copper (Cu) and abnormal glucose metabolism. Nevertheless, related researches on the relationship of Cu concentration and gestational diabetes mellitus (GDM) are limited. The objective of this study was to determine whether plasma Cu concentration is associated with GDM. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183260
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http://dx.doi.org/10.1016/j.clnu.2018.12.032DOI Listing
January 2019
6 Reads

Is there sufficient evidence to supplement omega-3 fatty acids to increase muscle mass and strength in young and older adults?

Clin Nutr 2019 Jan 7. Epub 2019 Jan 7.

School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil. Electronic address:

Omega-3 (ω-3) is a polyunsaturated fatty acid with anti-inflammatory properties that presents three main forms: alpha-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid. Recently, studies performed in both young and older adults suggest that ω-3 may improve gains in muscle mass and/or enhance physical function. Thus, the aim of this narrative review was to evaluate the current evidence of ω-3 intake/supplementation on muscle/lean mass (LM) and physical function in young and older adults, and draw research-based conclusions as to the practical implications of findings. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.001DOI Listing
January 2019
1 Read

Dietary glycemic index and glycemic load in relation to general obesity and central adiposity among adults.

Clin Nutr 2019 Jan 6. Epub 2019 Jan 6.

Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background & Aims: Although the association between dietary Glycemic Index (GI), Glycemic Load (GL) and general/abdominal obesity has extensively been examined, limited data are available in this regard in developing countries. The aim of this study was to examine the association between dietary GI and GL with general and abdominal obesity.

Methods: This cross-sectional study was conducted among adults in Isfahan, Iran. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.036DOI Listing
January 2019
2 Reads

Dietary fat, the gut microbiota, and metabolic health - A systematic review conducted within the MyNewGut project.

Clin Nutr 2018 Dec 24. Epub 2018 Dec 24.

Leibniz Institute for Prevention Research and Epidemiology - BIPS, Achterstraße 30, 28359 Bremen, Germany.

Background And Aims: Studies indicate that dietary fat quantity and quality influence the gut microbiota composition which may as a consequence impact metabolic health. This systematic review aims to summarize the results of available studies in humans on dietary fat intake (quantity and quality), the intestinal microbiota composition and related cardiometabolic health outcomes.

Methods: We performed a systematic review (CRD42018088685) following PRISMA guidelines and searched for literature in Medline, EMBASE, and Cochrane databases. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183259
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http://dx.doi.org/10.1016/j.clnu.2018.12.024DOI Listing
December 2018
6 Reads

Effect of oral citrulline supplementation on whole body protein metabolism in adult patients with short bowel syndrome: A pilot, randomized, double-blind, cross-over study.

Clin Nutr 2019 Jan 2. Epub 2019 Jan 2.

Nutrition Support Team, Division of Gastroenterology, IMAD, University Hospital, Nantes, France; INRA UMR 1280 PHAN, University of Nantes, IMAD, CRNH-Ouest, France. Electronic address:

Background & Aims: As citrulline is produced by small intestine, plasma citrulline concentration is decreased and may become essential in patients with short bowel syndrome (SBS). In a rat model of SBS, citrulline supplementation enhanced muscle protein synthesis. The aim of the study was to determine whether citrulline impacts whole body protein metabolism in patients with SBS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183259
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http://dx.doi.org/10.1016/j.clnu.2018.12.030DOI Listing
January 2019
7 Reads

Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial.

Clin Nutr 2018 Dec 10. Epub 2018 Dec 10.

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran. Electronic address:

Background And Aims: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic and selenium co-supplementation on cognitive function and metabolic status among patients with AD.

Methods: This randomized, double-blind, controlled clinical trial was conducted among 79 patients with AD. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.11.034DOI Listing
December 2018
2 Reads

Adaptation and predictive utility of a Mediterranean diet screener score.

Clin Nutr 2019 Jan 5. Epub 2019 Jan 5.

Cardiovascular Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Ramat Gan 52621, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 6997801, Israel.

Background & Aims: There is a substantial body of evidence supporting the health benefits of the Mediterranean diet, which has differing variations across the Mediterranean region. Abbreviated dietary screeners can be adapted and used to assess adherence to the local Mediterranean diet variant. We aimed to describe the process of adapting the Spanish Mediterranean Diet Adherence Screener (MEDAS) for use in Israel, and to test the predictive utility of the adapted score for mortality. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.034DOI Listing
January 2019
1 Read

Response to Letter re: Refeeding syndrome in adults receiving total parenteral nutrition: An audit of practice at a tertiary UK centre.

Clin Nutr 2019 Jan 5. Epub 2019 Jan 5.

Intestinal Failure Service, Department of Gastroenterology, University College London Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2PG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2018.10.029DOI Listing
January 2019
1 Read

Fluctuations in dietary intake during treatment for childhood leukemia: A report from the DALLT cohort.

Clin Nutr 2019 Jan 3. Epub 2019 Jan 3.

Department of Pediatrics, Roswell Park Cancer Institute and University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, United States.

Background: Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Nutritional morbidities are a persistent problem facing pediatric patients during and after treatment and age-gender groups that are at risk for nutritional conditions have not been clearly identified. Therapy is a contributing factor; however, the role of dietary intake remains largely unknown. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.021DOI Listing
January 2019
1 Read

Honey and cancer: A mechanistic review.

Clin Nutr 2018 Dec 27. Epub 2018 Dec 27.

Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Background: Globally, cancer ranks among the most common causes of death. Multiple experimental and clinical studies have investigated anticancer effects of honey with promising results. This study focused on potential background mechanisms of this effect. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.019DOI Listing
December 2018
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Four-oil intravenous lipid emulsion effect on plasma fatty acid composition, inflammatory markers and clinical outcomes in acutely ill patients: A randomised control trial (Foil fact).

Clin Nutr 2018 Dec 13. Epub 2018 Dec 13.

Division of Human Nutrition, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa.

Background And Aims: Data in critically ill patients on the effect of intravenous lipid emulsions (LEs), containing omega-3 polyunsaturated fatty acids (PUFAs), in parenteral nutrition (PN) are scarce and conflicting. This study compared the effects of a four-oil LE (30% soybean oil, 30% medium-chain triglycerides, 25% olive oil and 15% fish oil (FO)) (SMOFlipid®) to those of a 100% soybean oil-based LE in critically ill adult intensive care unit (ICU) patients.

Methods: In this double-blind, randomised study, patients (n = 75) predicted to need PN for more than 5 days were randomised to receive either a four-oil LE (Study Group (SG)) or a 100% soybean oil LE (Control Group (CG)). Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.010DOI Listing
December 2018
2 Reads

Essential amino acid-enriched meal replacement promotes superior net protein balance in older, overweight adults.

Clin Nutr 2018 Dec 19. Epub 2018 Dec 19.

Essential Blends, LLC, Fairbanks, AK, USA; Department of Geriatrics, Center for Translational Research in Aging & Longevity, Donald W. Reynolds Institute on Aging, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Background & Aims: Older individuals are susceptible to the loss of muscle and accumulation of fat. To address this problem, we have compared protein kinetics following consumption of an essential amino acid (EAA)-enriched meal replacement (EMR) to consumption of a high-protein meal replacement beverage (Bariatric Advantage, BA) using stable isotope methodology.

Methods: Eight older (67 ± 2), obese (35 ± 2 kg/m) female and male participants completed two studies using a randomized, crossover design in which they ingested each meal replacement. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183258
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http://dx.doi.org/10.1016/j.clnu.2018.12.013DOI Listing
December 2018
5 Reads

Associations of different body fat deposits with serum 25-hydroxyvitamin D concentrations.

Clin Nutr 2018 Dec 18. Epub 2018 Dec 18.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

Background & Aims: Obesity is a well-established risk factor of vitamin D deficiency. However, it is unclear which fat deposit is most strongly related to serum 25-hydroxyvitamin D (25(OH)D) concentrations. Our aim was to distinguish the specific contributions of total body fat (TBF), abdominal subcutaneous adipose tissue (aSAT), visceral adipose tissue (VAT) and hepatic fat on 25(OH)D concentrations. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.018DOI Listing
December 2018
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Sarcopenia as a predictor of poor surgical and oncologic outcomes after abdominal surgery for digestive tract cancer: A prospective cohort study.

Clin Nutr 2018 Dec 29. Epub 2018 Dec 29.

Department of General Surgery/Shanghai Clinical Nutrition Research Center, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

Background & Aims: Sarcopenia has been widely recognized as an important predictor of poor outcomes in patients with cancer after surgery, but the controversy remains, and its impact on surgical and oncologic outcomes in patients after abdominal surgery for digestive tract cancer is poorly described. The aim of this study was to evaluate the prognostic impact of sarcopenia on surgical and oncologic outcomes in patients after abdominal surgery for digestive tract cancer.

Methods: Six thousand four hundred and forty-seven consecutive patients who underwent abdominal surgery for digestive tract cancer in our institution were prospectively included. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.025DOI Listing
December 2018
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Coconut oil consumption improves fat-free mass, plasma HDL-cholesterol and insulin sensitivity in healthy men with normal BMI compared to peanut oil.

Clin Nutr 2018 Dec 29. Epub 2018 Dec 29.

Lipid Biochemistry Division, National Institute of Nutrition, Jamai Osmania, Hyderabad, 500 007, Telangana, India. Electronic address:

Background & Aims: The existing scientific evidence on coconut oil consumption and its health effects remains inconclusive due to varied reasons. In this context, we conducted a well-controlled metabolic study, eliminating some of the confounding factors and assessed the effects of the consumption of coconut oil-based diet on various anthropometric, biochemical and inflammatory markers and compared with peanut oil-diet.

Methods: Nine healthy male volunteers with BMI ≤25 kg/m were enrolled for this study and given balanced diets prepared with coconut oil (CO; ~35 g) for a period of eight weeks. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183259
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http://dx.doi.org/10.1016/j.clnu.2018.12.026DOI Listing
December 2018
9 Reads

Mini nutritional assessment is a better predictor of mortality than subjective global assessment in heart failure out-patients.

Clin Nutr 2018 Dec 10. Epub 2018 Dec 10.

ICREC Research Program, Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Badalona, Spain; CIBERCV, Instituto de Salud Carlos III, Madrid, Spain; Heart Failure Unit and Cardiology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.

Background & Aims: There is no consensus on the best method for nutritional screening and assessment in patients with heart failure (HF). This study aimed to determine which nutritional assessment method had the highest prognostic significance for patients with HF treated in outpatient clinics. We also aimed to identify a fast, reliable screening method for detecting malnutrition in these patients. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.001DOI Listing
December 2018
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CoCu: A new short questionnaire to evaluate diet composition and culture of eating in children and adolescents.

Clin Nutr 2018 Dec 27. Epub 2018 Dec 27.

LIFE - Leipzig Research Center for Civilization Diseases, Leipzig University, Philipp-Rosenthal-Strasse 27, 04103 Leipzig, Germany; Department of Women and Child Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), Leipzig University, Liebigstrasse 20a, 04103 Leipzig, Germany. Electronic address:

Background & Aims: The aim of this project was to develop and validate a short questionnaire (titled CoCu - Composition and Culture of Eating) for assessing the composition of the diets of children and adolescents, and their culture of eating. We also investigated whether what and how children eat is associated with their age, gender, and social background.

Methods: The "diet composition" part of the developed questionnaire contains 14 questions about the number of portions of different food products the subject child eats per week or per day. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.12.020DOI Listing
December 2018
4 Reads

Cross sectional imaging of truncal and quadriceps muscles relates to different functional outcomes in cancer.

Clin Nutr 2018 Dec 24. Epub 2018 Dec 24.

Clinical and Surgical Sciences, University of Edinburgh, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, United Kingdom.

Introduction: Following the consensus definition of cancer cachexia, more studies are using CT scan analysis of truncal muscles as a marker of muscle wasting. However, how CT-derived body composition relates to function, strength and power in patients with cancer is largely unknown.

Aims: We aimed to describe the relationship between CT truncal (L3) skeletal muscle index (SMI) and MRI quadriceps cross sectional area with lower limb strength, power and measures of complex function. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02615614183259
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http://dx.doi.org/10.1016/j.clnu.2018.12.023DOI Listing
December 2018
6 Reads

Clinical association between the metabolite of healthy gut microbiota, 3-indolepropionic acid and chronic kidney disease.

Clin Nutr 2018 Dec 27. Epub 2018 Dec 27.

Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei, Taiwan; Department of Food Science, Nutrition, and Nutraceutical Biotechnology, Shih-Chien University, Taipei, Taiwan.

Background & Aims: Emerging evidence indicates that gut microbiota serves an important role in the development and progression of chronic kidney disease (CKD). Changes to the gut microbial flora can cause the generation of uremic toxins, which contribute to chronic kidney injury. The aim of the current study was to explore the clinical association between metabolites and CKD. Read More

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http://dx.doi.org/10.1016/j.clnu.2018.11.029DOI Listing
December 2018
9 Reads