3 results match your criteria Clinical Medicine Insights: Therapeutics [Journal]

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Nonalcoholic Fatty Liver Disease: Epidemiology, Pathogenesis, Natural History, Diagnosis, and Current Treatment Options.

Clin Med Insights Ther 2016 18;8:75-84. Epub 2016 Dec 18.

Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University Medical Center, Richmond, VA, USA.

Nonalcoholic fatty liver disease (NAFLD) is on the rise and has become a major etiology for chronic liver disease. It is frequently associated with obesity, insulin resistance, hypertension, and dyslipidemia and is considered the hepatic manifestation of metabolic syndrome. In this review, we present a summary of the epidemiology and pathogenesis of NAFLD, and discuss the clinical evaluation and stratification of NAFLD patients into low, intermediate, and high risk with respect to liver-related outcomes. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491796PMC
December 2016
21 Reads

Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris.

Clin Med Insights Ther 2013 Jan;2013(5):1-14

Department of Anesthesiology, The Medical College of wisconsin, Milwaukee, WI, USA ; Cardiovascular research Center, The Medical College of Wisconsin, Milwaukee, WI, USA.

Coronary heart disease is a global malady and it is the leading cause of death in the United States. Chronic stable angina is the most common manifestation of coronary heart disease and it results from the imbalance between myocardial oxygen supply and demand due to reduction in coronary blood flow. Therefore, in addition to lifestyle changes, commonly used pharmaceutical treatments for angina (nitrates, β-blockers, Ca channel blockers) are aimed at increasing blood flow or decreasing O demand. Read More

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http://dx.doi.org/10.4137/CMT.S7824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932785PMC
January 2013
7 Reads

Cisplatin-Based Chemotherapy Options for Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck.

Clin Med Insights Ther 2013 ;2013(5)

University of Pittsburgh, Department of Otolaryngology, Eye and Ear Institute, Pittsburgh, PA.

Recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a devastating malignancy with a poor prognosis. Treatment is limited to chemotherapeutic approaches. Cisplatin is an established and effective treatment for R/M HNSCC, and many studies have investigated cisplatin treatment in combination with other agents. Read More

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http://dx.doi.org/10.4137/CMT.S10409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835153PMC
January 2013
10 Reads
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