12 results match your criteria Clinical Medicine Insights: Psychiatry [Journal]

  • Page 1 of 1

Youth at-risk for serious mental illness: methods of the PROCAN study.

BMC Psychiatry 2018 Jul 5;18(1):219. Epub 2018 Jul 5.

Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Mathison Centre, 3280 Hospital Dr NW, Calgary, AB, Calgary, AB, T2N 4Z6, Canada.

Background: Most mental disorders begin in adolescence; however, there are gaps in our understanding of youth mental health. Clinical and policy gaps arise from our current inability to predict, from amongst all youth who experience mild behavioural disturbances, who will go on to develop a mental illness, what that illness will be, and what can be done to change its course and prevent its worsening to a serious mental illness (SMI). There are also gaps in our understanding of how known risk factors set off neurobiological changes that may play a role in determining who will develop a SMI. Read More

View Article

Download full-text PDF

Source
https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12
Publisher Site
http://dx.doi.org/10.1186/s12888-018-1801-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034268PMC
July 2018
5 Reads

Study protocol for The Emory 3q29 Project: evaluation of neurodevelopmental, psychiatric, and medical symptoms in 3q29 deletion syndrome.

BMC Psychiatry 2018 Jun 8;18(1):183. Epub 2018 Jun 8.

Department of Human Genetics, Emory University School of Medicine, Whitehead Research Building, 615 Michael Street, Suite 300, Atlanta, GA, 30322, USA.

Background: 3q29 deletion syndrome is caused by a recurrent hemizygous 1.6 Mb deletion on the long arm of chromosome 3. The syndrome is rare (1 in 30,000 individuals) and is associated with mild to moderate intellectual disability, increased risk for autism and anxiety, and a 40-fold increased risk for schizophrenia, along with a host of physical manifestations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-018-1760-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994080PMC
June 2018
23 Reads

Experiences of parenting and clinical intervention for mothers affected by personality disorder: a pilot qualitative study combining parent and clinician perspectives.

BMC Psychiatry 2018 May 25;18(1):152. Epub 2018 May 25.

CAMHS Research Unit, IOPPN, King's College London, Michael Rutter Centre, De Crespigny Park, Camberwell, London, SE5 8AZ, UK.

Background: Evidence-based parenting programmes are recommended for the treatment of child mental health difficulties. Families with complex psychosocial needs show poorer retention and outcomes when participating in standard parenting programmes. The Helping Families Programme (HFP) is a 16-week community-based parenting intervention designed to meet the needs of these families, including families with parental personality disorder. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-018-1733-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970472PMC
May 2018
5 Reads

The SyBil-AA real-time fMRI neurofeedback study: protocol of a single-blind randomized controlled trial in alcohol use disorder.

BMC Psychiatry 2018 01 17;18(1):12. Epub 2018 Jan 17.

Department of Clinical Psychology, Central Institute of Mental Health (ZI), University of Heidelberg/Medical Faculty Mannheim, J5, 68159, Mannheim, Germany.

Background: Alcohol Use Disorder is a highly prevalent mental disorder which puts a severe burden on individuals, families, and society. The treatment of Alcohol Use Disorder is challenging and novel and innovative treatment approaches are needed to expand treatment options. A promising neuroscience-based intervention method that allows targeting cortical as well as subcortical brain processes is real-time functional magnetic resonance imaging neurofeedback. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-018-1604-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773029PMC
January 2018
19 Reads

ESCAschool study: trial protocol of an adaptive treatment approach for school-age children with ADHD including two randomised trials.

BMC Psychiatry 2017 07 24;17(1):269. Epub 2017 Jul 24.

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Medical Faculty of the University of Cologne, Robert-Koch-Str. 10, 50931, Cologne, Germany.

Background: The ESCAschool study addresses the treatment of school-age children with attention-deficit/hyperactivity disorder (ADHD) in a large multicentre trial. It aims to investigate three interrelated topics: (i) Clinical guidelines often recommend a stepped care approach, including different treatment strategies for children with mild to moderate and severe ADHD symptoms, respectively. However, this approach has not yet been empirically validated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-017-1433-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525245PMC
July 2017
36 Reads

A case of recurrent depressive disorder presenting with Alice in Wonderland syndrome: psychopathology and pre- and post-treatment FDG-PET findings.

BMC Psychiatry 2017 04 27;17(1):150. Epub 2017 Apr 27.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Background: Alice in Wonderland syndrome (AIWS) is a rare neuropsychiatric syndrome that typically manifests in distortion of extrapersonal visual image, altered perception of one's body image, and a disturbed sense of the passage of distance and time. Several conditions have been reported to contribute to AIWS, although its biological basis is still unknown. Here, we present the first case demonstrating a clear concurrence of recurrent depressive disorder and AIWS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-017-1314-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408427PMC
April 2017
13 Reads

Can tobacco dependence provide insights into other drug addictions?

BMC Psychiatry 2016 10 27;16(1):365. Epub 2016 Oct 27.

Department of Family Medicine and Community Health, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.

Within the field of addiction research, individuals tend to operate within silos of knowledge focused on specific drug classes. The discovery that tobacco dependence develops in a progression of stages and that the latency to the onset of withdrawal symptoms after the last use of tobacco changes over time have provided insights into how tobacco dependence develops that might be applied to the study of other drugs.As physical dependence on tobacco develops, it progresses through previously unrecognized clinical stages of wanting, craving and needing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-016-1074-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081932PMC
October 2016
5 Reads

Gut to brain interaction in Autism Spectrum Disorders: a randomized controlled trial on the role of probiotics on clinical, biochemical and neurophysiological parameters.

BMC Psychiatry 2016 06 4;16:183. Epub 2016 Jun 4.

IRCCS Stella Maris Foundation, Viale del Tirreno 331, 56018, Calambrone, Pisa, Italy.

Background: A high prevalence of a variety of gastrointestinal (GI) symptoms is frequently reported in patients with Autism Spectrum Disorders (ASD). The GI disturbances in ASD might be linked to gut dysbiosis representing the observable phenotype of a "gut-brain axis" disruption. The exploitation of strategies which can restore normal gut microbiota and reduce the gut production and absorption of toxins, such as probiotics addition/supplementation in a diet, may represent a non-pharmacological option in the treatment of GI disturbances in ASD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-016-0887-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893248PMC
June 2016
23 Reads

The Danish 22q11 research initiative.

BMC Psychiatry 2015 Sep 17;15:220. Epub 2015 Sep 17.

Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Copenhagen University Hospital, Boserupvej 2, DK-4000, Roskilde, Denmark.

Background: Neurodevelopmental brain disorders such as schizophrenia, autism and attention deficit hyperactivity disorder are complex disorders with heterogeneous etiologies. Schizophrenia and autism are difficult to treat and often cause major individual suffering largely owing to our limited understanding of the disease biology. Thus our understanding of the biological pathogenesis needs to be substantiated to enable development of more targeted treatment options with improved efficacy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-015-0594-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574168PMC
September 2015
21 Reads

Neural origins of psychosocial functioning impairments in major depression.

Lancet Psychiatry 2015 Sep;2(9):835-43

Neuroscience and Psychiatry Unit, School of Medicine, The University of Manchester and Manchester Academic Health Sciences Centre, Manchester, UK.

Major depressive disorder, a complex neuropsychiatric condition, is associated with psychosocial functioning impairments that could become chronic even after symptoms remit. Social functioning impairments in patients could also pose coping difficulties to individuals around them. In this Personal View, we trace the potential neurobiological origins of these impairments down to three candidate domains-namely, social perception and emotion processing, motivation and reward value processing, and social decision making. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2215-0366(15)00237-0DOI Listing
September 2015
7 Reads

Hypoglutamatergic state is associated with reduced cerebral glucose metabolism in anti-NMDA receptor encephalitis: a case report.

BMC Psychiatry 2015 Aug 1;15:186. Epub 2015 Aug 1.

Section of Experimental Neuropsychiatry, Department for Psychiatry& Psychotherapy, University Medical Center Freiburg, Hauptstr. 5, 79104, Freiburg, Germany.

Background: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis was first described in 2005 in association with ovarian teratoma. The diagnostic workup of this common autoimmune encephalitis includes cerebrospinal fluid analysis, electroencephalography, magnetic resonance imaging (MRI), and fluorodeoxyglucose positron emission tomography (FDG-PET). In addition to standard diagnostics, we performed metabolic investigations using proton magnet resonance spectroscopy ((1)H-MRS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12888-015-0552-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522073PMC
August 2015
16 Reads

Integrative psychobiological approach to psychiatric assessment and treatment.

Psychiatry 1997 ;60(2):120-41

Center for Psychobiology of Personality, Washington University School of Medicine, St. Louis, MO 63110, USA.

A Developmental approach to integrative psychobiology provides a flexible framework for both clinical assessment and treatment planning. Assessment of seven dimensions of personality using the Temperament and Character Inventory (TCI) allows for comprehensive description of individual differences in feelings, thoughts, and actions. Four temperament factors that are stable throughout life can be decomposed in terms of their underlying genetic structure. Read More

View Article

Download full-text PDF

Source
November 1997
8 Reads
  • Page 1 of 1