251 results match your criteria Clinical Medicine Insights: Case Reports [Journal]


Palliative Surgical Resection of an Extensive Metastatic Cardiac Myxofibrosarcoma.

Clin Med Insights Case Rep 2019 1;12:1179547619837312. Epub 2019 Apr 1.

Division of Cardiac Surgery, Department of Surgery, University of Toronto and St. Michael's Hospital, Toronto, ON, Canada.

Herein, we report a rare case of metastatic secondary cardiac myxofibrosarcoma in a 33-year-old female patient. The tumor infiltrated the right lung and was extending into the heart via the right superior pulmonary vein. The patient who initially presented with a stroke was found to be at a high risk of recurrent embolic events and therefore was managed successfully surgically with a complex joint thoracic and cardiac tumor resection. Read More

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http://dx.doi.org/10.1177/1179547619837312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444771PMC
April 2019
3 Reads

A Novel Variant c.847T>C in Gene Leading to Pycnodysostosis: A Case Report.

Clin Med Insights Case Rep 2019 1;12:1179547619837234. Epub 2019 Apr 1.

Department of Pediatrics, Aligarh Muslim University, Aligarh, India.

Pycnodysostosis is a rare genetic disorder with a prevalence of 1.7 per million births; it usually presents with short stature, osteosclerosis, increased bone fragility, and acro-osteolysis of distal phalanges. There are less than 200 cases reported worldwide and very few from South-East Asia. Read More

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http://dx.doi.org/10.1177/1179547619837234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444763PMC

Lack of Transmission of Zika Virus Infection to Breastfed Infant.

Clin Med Insights Case Rep 2019 12;12:1179547619835179. Epub 2019 Mar 12.

Thai Red Cross Emerging Infectious Diseases - Health Science Centre, World Health Organization Collaborating Centre for Research and Training on Viral Zoonoses, Chulalongkorn Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Zika virus (ZIKV) continues to affect certain parts of the World. Here we report a case that supports breastfeeding regardless of mother ZIKV status by providing clinical and virological studies. Read More

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http://dx.doi.org/10.1177/1179547619835179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415467PMC

Peritoneal Dialysis and Malignancy: An Experience With a Patient Complicated by Gastric Carcinoma.

Clin Med Insights Case Rep 2019 12;12:1179547619835176. Epub 2019 Mar 12.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.

An 86-year-old man who had been treated with peritoneal dialysis for 14°months due to end-stage kidney disease secondary to hypertensive nephrosclerosis presented with a recent history of malaise, abdominal discomfort, and anorexia. An endoscopic evaluation revealed an elevated, ulcerated, and friable lesion around the lesser curvature of the stomach. The concurrent gastric biopsy specimens revealed moderately differentiated adenocarcinoma, while a cytological examination of the dialysis fluid revealed clusters of malignant cells. Read More

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http://dx.doi.org/10.1177/1179547619835176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415473PMC
March 2019
2 Reads

Sphenoid Sinus Cholesteatoma-Complications and Skull Base Osteomyelitis: Case Report and Review of Literature.

Clin Med Insights Case Rep 2019 5;12:1179547619835182. Epub 2019 Mar 5.

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Introduction: Cholesteatoma of the paranasal sinuses is uncommon. Its clinical characteristics are an expanding growth of the affected paranasal sinuses consisting of keratinizing squamous epithelium with bony wall destruction. Among involved paranasal sinuses, sphenoid sinus cholesteatoma is the least common. Read More

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http://journals.sagepub.com/doi/10.1177/1179547619835182
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http://dx.doi.org/10.1177/1179547619835182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402053PMC
March 2019
5 Reads

Fracture of the Port Catheter and Migration Into the Coronary Sinus: Case Report and Brief Review of the Literature.

Clin Med Insights Case Rep 2019 27;12:1179547619832282. Epub 2019 Feb 27.

Department of Cardiology and Vascular Medicine, Siloam Hospitals Lippo Village - Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia.

Introduction: Totally implantable venous device has a good safety profile, although certain complications may occur. Late mechanical complications include catheter fracture and cardiac migration which are rarely occurring in approximately 0.1% to 1% of patients. Read More

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http://dx.doi.org/10.1177/1179547619832282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393817PMC
February 2019
1 Read

Acute Symptomatic Sinus Bradycardia in High-Dose Methylprednisolone Therapy in a Woman With Inflammatory Myelitis: A Case Report and Review of the Literature.

Clin Med Insights Case Rep 2019 25;12:1179547619831026. Epub 2019 Feb 25.

Department of Neurological and Psychiatric sciences (NEUROFARBA), University of Florence, Florence, Italy.

High dose corticosteroid therapy is widely used as attack therapy of inflammatory central nervous system disorders and can induce several adverse reactions. Bradycardia is an infrequent event after corticosteroids administration and is often asymptomatic. We report a case of a woman admitted to the neurological department of our hospital for paraesthesias of the lower limbs. Read More

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http://dx.doi.org/10.1177/1179547619831026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390212PMC
February 2019
2 Reads

Identification of an p.Gly292fs Frameshift Mutation Presenting as Diabetes During Pregnancy in a Maltese Family.

Clin Med Insights Case Rep 2019 20;12:1179547619831034. Epub 2019 Feb 20.

Department of Medicine, Mater Dei Hospital, Msida, Malta.

The diagnosis of maturity onset diabetes of the young (MODY) is a challenging process in view of the extensive clinical and genetic heterogeneity of the disease. Mutations in the gene encoding hepatocyte nuclear factor 1α () are responsible for most forms of monogenic diabetes in Northern European populations. Genetic analysis through a combination of whole exome sequencing and Sanger sequencing in three Maltese siblings and their father identified a rare duplication/frameshift mutation in exon 4 of that lies within a known mutational hotspot in this gene. Read More

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http://dx.doi.org/10.1177/1179547619831034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383084PMC
February 2019
7 Reads

Small Septal Branch Artery Thrombus Inducing Ventricular Fibrillation: To Intervene or Not to Intervene.

Clin Med Insights Case Rep 2019 15;12:1179547619828717. Epub 2019 Feb 15.

Department of Cardiology, Staten Island University Hospital, Northwell Health, Staten Island, NY, USA.

A 64-year-old woman presented for chest pain and was diagnosed with anteroseptal ST segment elevation myocardial infarction (STEMI). Emergent angiography showed 95% stenosis at the ostium of the second septal branch, consistent with thrombus, and no other significant lesions. The lesion was not amenable to intervention due to small caliber. Read More

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http://dx.doi.org/10.1177/1179547619828717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378485PMC
February 2019
2 Reads

Possibly Late-Onset Arrhythmogenic Right Ventricular Cardiomyopathy: Unique Triglyceride Deposition by Analysis of Lipid Contents.

Clin Med Insights Case Rep 2019 15;12:1179547619828715. Epub 2019 Feb 15.

Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada, Japan.

We presented an unusual arrhythmogenic right ventricular cardiomyopathy (ARVC) case of a late-60s elderly man's death, due to severe pericardial/pleural effusion and ascites, and arrhythmic events, with unique pathological features. The hypertrophic heart grossly displayed yellowish to yellow-whitish predominantly in the variably thinned wall of the dilated right ventricle. Microscopic findings showed diffuse fatty/fibrofatty replacement in not only the right but left ventricular myocardium, together with an outer lymphoplasmacytic infiltrate. Read More

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http://dx.doi.org/10.1177/1179547619828715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378422PMC
February 2019

Waldenström Macroglobulinemia: Unusual Presentation With Cast Nephropathy/Light Chain Tubulopathy.

Clin Med Insights Case Rep 2019 15;12:1179547619828704. Epub 2019 Feb 15.

Department of Pathology, University of Iowa Health Care, Iowa City, IA, USA.

Cast Nephropathy/Light chain tubulopathy is usually present in patients with multiple myeloma and is very rare in patients with Waldenstrom Macroglobulinemia. There are very few case reports mentioned in the literature. We present an interesting case of Cast Nephropathy and light chain tubulopathy in an 81-year-old female patient with Waldenstrom Macroglobulinemia who required medical attention for worsening renal failure. Read More

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http://dx.doi.org/10.1177/1179547619828704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378479PMC
February 2019
1 Read

Aggressive Digital Papillary Adenocarcinoma at Atypical Site.

Clin Med Insights Case Rep 2019 7;12:1179547619828723. Epub 2019 Feb 7.

Department of General Surgery, Indira Gandhi Medical College, Shimla, India.

Aggressive digital papillary adenocarcinoma (ADPA) is a rare tumour of eccrine origin. They present as asymptomatic nodules with flattened and thickened surface skin, most commonly on fingers and toes. It mimics many benign entities and tumours, hence leading to a delay in diagnosis. Read More

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http://dx.doi.org/10.1177/1179547619828723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376506PMC
February 2019
1 Read

Treatment of Renal Artery Stenosis in a Solitary Kidney Using Cutting Balloon Angioplasty in a Paediatric Patient.

Clin Med Insights Case Rep 2019 7;12:1179547619828721. Epub 2019 Feb 7.

Department of Interventional Radiology, Queen's Medical Centre (QMC), Nottingham University Hospitals NHS Trust, Nottingham, UK.

Aims: Renovascular hypertension is a rare cause of paediatric hypertension. It is however, a potentially treatable cause particularly when caused by renal artery stenosis (RAS).

Materials And Methods: We present the case of an 11-month-old girl presenting with cardiac dysfunction. Read More

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http://dx.doi.org/10.1177/1179547619828721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376492PMC
February 2019

Homozygous Factor V Leiden Thrombophilia in a Patient With Histologically Confirmed Thromboangiitis Obliterans.

Clin Med Insights Case Rep 2019 7;12:1179547619828719. Epub 2019 Feb 7.

Reconstructive Surgery and Regenerative Medicine Research Group, Welsh Centre for Burns and Plastic Surgery, Morriston Hospital, Swansea, UK.

Thromboangiitis obliterans (TAO) is a vasculitis characterised by segmental occlusions of small to medium-sized arteries and superficial veins, and a curious predilection for young male smokers. The exact aetiology remains unknown. Current theories postulate it is an autoimmune endarteritis, triggered by some constituent of tobacco and occurring in genetically susceptible individuals. Read More

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http://dx.doi.org/10.1177/1179547619828719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376526PMC
February 2019
1 Read

Retroperitoneal Hematoma: Rupture of Aneurysm in the Arc of Bühler Caused by Median Arcuate Ligament Syndrome.

Clin Med Insights Case Rep 2019 7;12:1179547619828716. Epub 2019 Feb 7.

Department of Gastroenterology, Dokkyo Medical University, Mibu, Japan.

We herein report a case with aneurysm rupture in the arc of Bühler (AOB) caused by median arcuate ligament syndrome (MALS). The patient experienced a sudden onset of upper abdominal pain. Contrast-enhanced abdominal computed tomography (CT) showed an iso- to hyper-enhancing area mainly ranging from the dorsal aspect of the pancreatic head to the retroperitoneum around the right kidney. Read More

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http://dx.doi.org/10.1177/1179547619828716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376540PMC
February 2019

A Novel Intervention to Treat Failed Angio-Seal Footplate Deployment: Two Case Series.

Clin Med Insights Case Rep 2019 8;12:1179547619828714. Epub 2019 Feb 8.

Department of Radiology, Queen's Medical Centre (QMC), Nottingham University Hospitals NHS Trust, Nottingham, UK.

Introduction: Vascular closure devices are commonly used to achieve rapid haemostasis and early ambulation following arterial puncture for endovascular procedures. Although device failure rates are low, the consequences of arterial occlusion include severe limb ischaemia. We describe a novel endovascular technique for the treatment of Angio-Seal arterial closure device (Terumo, Europe NV) failure causing femoral artery occlusion. Read More

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http://dx.doi.org/10.1177/1179547619828714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376524PMC
February 2019
1 Read

Post Coronary Artery Bypass Grafting Failure-Don't Always Blame the Blues!!

Clin Med Insights Case Rep 2019 13;12:1179547619828711. Epub 2019 Feb 13.

Department of Cardiology, King George's Medical University, Lucknow, India.

Long term outcomes following coronary artery bypass grafting are governed by patency of vascular grafts. In this regard, the use of arterial grafts, (preferably the left internal mammary artery) has demonstrated improved survival relative to venous their counterparts. These benefits are a consequence of greater patency of LIMA at 10 years vis-a-vis venous grafts. Read More

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http://dx.doi.org/10.1177/1179547619828711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376548PMC
February 2019
1 Read

A Case of Critical Calcified Innominate Artery Stenosis Successfully Treated With the Shockwave Lithoplasty.

Clin Med Insights Case Rep 2019 12;12:1179547619828707. Epub 2019 Feb 12.

Cardiology Unit, Sant'Anna Hospital, Catanzaro, Italy.

Purpose: The Shockwave Lithoplasty System represents a novel technology combining a balloon angioplasty catheter with the use of sound waves. Evidences suggest that it is a reliable tool to overcome calcified stenosis in both peripheral and coronary arteries. Here, we describe the case of a patient with calcified innominate artery stenosis successfully treated with the Shockwave Lithoplasty System. Read More

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http://dx.doi.org/10.1177/1179547619828707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376523PMC
February 2019
2 Reads

Exclusion of a Giant Coronary Artery Aneurysm With Covered Stents Using a Long Drug-Eluting Stent Scaffold.

Clin Med Insights Case Rep 2019 7;12:1179547619828689. Epub 2019 Feb 7.

Division of Cardiology, School of Medicine, University of Colorado, Aurora, CO, USA.

Coronary artery aneurysms (CAA) are a rare cause of acute coronary syndrome and there is little consensus as to the optimal treatment. Based on case series as well as expert opinion, surgery has been suggested as the optimal treatment for a giant CAA. Here, we present the case of a patient with recurrent myocardial infarction and severe angina due to a giant CAA, who was deemed a poor surgical candidate due to his multiple medical comorbidities. Read More

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http://dx.doi.org/10.1177/1179547619828689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376528PMC
February 2019
1 Read

Redundancy Is of No Good; Iatrogenic Hypervitaminosis D: A Rare Case of Persistent Vomiting Due to Hypercalcemia.

Clin Med Insights Case Rep 2019 7;12:1179547619828688. Epub 2019 Feb 7.

Department of Internal Medicine, Jinnah Medical College Hospital, Karachi, Pakistan.

Introduction: Iatrogenic or physician-induced hypervitaminosis D is a rare cause of persistent vomiting. To the best of our knowledge, this is the first case report on iatrogenic hypervitaminosis D presenting with persistent vomiting in Pakistan.

Case Report: We report a rare case of continual vomiting for 15 days in a 48-year-old woman of Pakistani descent. Read More

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http://dx.doi.org/10.1177/1179547619828688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376501PMC
February 2019
1 Read

A Tale of Two Knee Implants in the Same Person: Narcotics for the First and Anti-inflammatory Drugs for the Second.

Clin Med Insights Case Rep 2018 27;11:1179547618794650. Epub 2018 Aug 27.

Division of Home Health, Scripps Clinic, San Diego, CA, USA.

Opioid addiction is a world-wide tragedy, with severe consequences for both the victims and the society that must care for them. The pathways to addiction are multiple but postoperative opioid prescriptions for pain management are a major contributor to this crisis. This case report describes the differences in pain management during 2 different arthroplasties of the knees in the same person. Read More

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http://dx.doi.org/10.1177/1179547618794650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111394PMC
August 2018
10 Reads

Short-Term Outcomes of Treatment of Hip Osteoarthritis With 4 Bone Marrow Concentrate Injections: A Case Series.

Clin Med Insights Case Rep 2018 10;11:1179547618791574. Epub 2018 Aug 10.

Darrow Stem Cell Institute, Los Angeles, CA, USA.

The use of mesenchymal stem cells from bone marrow concentrate (BMC) has become an increasingly popular option as an alternative to total joint replacement. Although there is evidence to support the use of BMC injections to improve quality of life for patients with knee osteoarthritis (OA), there is limited evidence to support its use in patients with hip OA. This case series provides the short-term outcomes of 4 hip OA patients who each underwent 4 BMC injections. Read More

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http://dx.doi.org/10.1177/1179547618791574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088468PMC
August 2018
4 Reads

A Case of Obstructive Jaundice Caused by Metastasis of Ovarian Cancer to the Duodenal Major Papilla.

Clin Med Insights Case Rep 2018 3;11:1179547618791571. Epub 2018 Aug 3.

Department of Pathology, Aizu Medical Center, Fukushima Medical University, Fukushima, Japan.

Ovarian cancer often occurs distant metastasis to the peritoneum, liver, lungs, and lymph nodes. However, there has been no reported case of direct metastasis to the duodenal major papilla. We herein reported 72-year-old woman with history of ovarian cancer surgery 11 years ago presenting with obstructive jaundice. Read More

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http://dx.doi.org/10.1177/1179547618791571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077891PMC
August 2018
8 Reads

Hemolytic Uremic Syndrome: An Increasingly Recognized Public Health Problem.

Clin Med Insights Case Rep 2018 3;11:1179547618785137. Epub 2018 Jul 3.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.

A 28-year-old man was referred and admitted to our hospital due to O157-mediated hemorrhagic colitis with severe thrombocytopenia. A systemic workup concluded that the patient had acute pancreatitis as well as hemolytic uremic syndrome. The patient was ultimately discharged, with his platelet count having recovered. Read More

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http://dx.doi.org/10.1177/1179547618785137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069030PMC
July 2018
27 Reads

A Case of Upper Ureter Rupture With Acute Kidney Injury.

Clin Med Insights Case Rep 2018 27;11:1179547618785134. Epub 2018 Jun 27.

Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

We herein report a case of ureter rupture with severe oliguric acute renal injury due to benign prostatic hypertrophy. After insertion of an indwelling urinary catheter, the patient's urine output immediately increased. His symptoms and renal function also rapidly improved to the normal range without a surgical operation. Read More

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http://dx.doi.org/10.1177/1179547618785134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069021PMC
June 2018
3 Reads

Graves Disease Causing Pancytopenia: Case Report and Literature Review.

Clin Med Insights Case Rep 2018 25;11:1179547618781090. Epub 2018 Jun 25.

ENT Surgery Department, University Hospital Centre (CHUV), Lausanne, Switzerland.

Background: Graves disease or other causes of thyrotoxicosis are frequently associated with cytopenia. Although anemia is the most common, other cell lineage can be affected. Pancytopenia is a rare complication of thyrotoxicosis. Read More

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http://dx.doi.org/10.1177/1179547618781090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069025PMC
June 2018
2 Reads

Total Knee Arthroplasty for Chronic Anterior Knee Dislocation.

Clin Med Insights Case Rep 2018 22;11:1179547618782882. Epub 2018 Jun 22.

Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: The occurrence of chronic knee dislocation is rare. To the best of our knowledge, total knee arthroplasty for treatment of chronic anterior knee dislocation has not been reported.

Method: This report describes 3 cases of chronic anterior knee dislocation treated by total knee arthroplasty. Read More

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http://dx.doi.org/10.1177/1179547618782882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024489PMC
June 2018
22 Reads

Hydroxyurea-Induced Pneumopathy in a Patient With Myeloproliferative Syndrome.

Clin Med Insights Case Rep 2018 23;11:1179547618770688. Epub 2018 Apr 23.

Department of Intensive and Critical Care, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

Hydroxyurea (HU) is a drug frequently used in the treatment of chronic myeloproliferative neoplasms. The most common side effects of this drug are pancytopenia, digestive and skin disorders. Respiratory complications are rare and there are less than 20 cases described, only 5 of which underwent an anatomopathological study. Read More

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http://dx.doi.org/10.1177/1179547618770688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993068PMC
April 2018
22 Reads

Simultaneous Gastric Metastasis From Renal Cell Carcinoma: A Case Report and Literature Review.

Clin Med Insights Case Rep 2018 22;11:1179547618775095. Epub 2018 May 22.

Department of Pathology, Fukushima Medical University Aizu Medical Center, Aizuwakamatsu, Japan.

While some reports are available regarding metachronous gastric metastasis from renal cell carcinoma after treatment, there are few reports of primary lesion detection based on the diagnosis of a gastric metastatic lesion. The patient in this case was an 80-year-old woman who underwent upper gastrointestinal endoscopy after having developed anorexia 2 months earlier. A submucosal tumor with central umbilication was found in the gastric greater curvature. Read More

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http://dx.doi.org/10.1177/1179547618775095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967158PMC
May 2018
5 Reads

Trends of Gallbladder Cancer in Jordan Over 2 Decades: Where Are We?

Clin Med Insights Case Rep 2018 20;11:1179547618771699. Epub 2018 Apr 20.

Department of Pathology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Background And Study Aims: The prevalence of gallbladder cancer (GBC) varies between different parts of the world. This study is a review of literature and an update of a previously published study conducted in our university and aims to reassess the incidence of GBC over the past 2 decades.

Patients And Methods: We conducted a retrospective study between 2002 and 2016. Read More

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http://dx.doi.org/10.1177/1179547618771699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946354PMC
April 2018
8 Reads

Pancreatitis Is a Silent Killer in Peritoneal Dialysis With Difficult Diagnostic Approach.

Clin Med Insights Case Rep 2018 26;11:1179547618765761. Epub 2018 Mar 26.

Section of Nephrology, Department of Clinical and Experimental Medicine, Policlinico Universitario, University of Catania, Catania, Italy.

Until 2018, 236 cases of acute pancreatitis have been reported in patients who underwent peritoneal dialysis. Here, we presented a patient with double renal transplantation with chronic renal failure, under renal replacement therapy by peritoneal dialysis, who developed acute pancreatitis with abdominal pain, nausea, vomiting, leukocytosis with neutrophil left shift which is complicated by pancreatic pseudocyst, candida peritonitis, fungal sepsis, overlapping of sepsis, and pneumonitis. After the percutaneous cystogastrostomy drainage of pancreatic pseudocyst, changes from peritoneal dialysis to hemodialysis, various thoracentesis, and polyantibiotics therapy, the resolution of the sepsis state was seen. Read More

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http://dx.doi.org/10.1177/1179547618765761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888805PMC
March 2018
8 Reads

Hypoglycemic Coma in a Hemodialysis Patient Receiving Blood Glucose-Lowering Therapy With the Single Agent Teneligliptin.

Clin Med Insights Case Rep 2018 20;11:1179547618763358. Epub 2018 Mar 20.

Division of Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.

Blood glucose management in patients undergoing dialysis is clinically challenging. In this population, most conventional oral hypoglycemic agents are contraindicated, especially from the perspective of pharmacokinetics. Dipeptidyl peptidase-4 inhibitors exert unique pharmacologic actions via glucose-dependent mechanism and have an excellent tolerability profile with a very low risk of hypoglycemia. Read More

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http://dx.doi.org/10.1177/1179547618763358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863859PMC
March 2018
17 Reads

Acquired von Willebrand Syndrome Complicating Nephrotic Syndrome: A Case of a Patient With Membranous Nephropathy.

Clin Med Insights Case Rep 2018 13;11:1179547618763371. Epub 2018 Mar 13.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.

Acquired von Willebrand syndrome (AVWS) is a rare clinical entity presenting with heterogeneous hemorrhagic manifestations, although some subsets of patients with AVWS may be asymptomatic until they are exposed to major trauma, an invasive procedure, or surgery. We herein report one such case in a 73-year-old male patient with nephrotic syndrome with a prolonged active partial thromboplastin time. We initially did not deal with this distinct abnormal clotting profile seriously, but persistent bleeding after a retroperitoneoscopic-assisted renal biopsy that allowed us to ascribe his nephrotic syndrome to membranous nephropathy fortuitously led to the discovery of concurrent AVWS. Read More

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http://dx.doi.org/10.1177/1179547618763371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858607PMC
March 2018
9 Reads

Severe Myopericarditis in Diabetic Ketoacidosis-All Troponin are Not Myocardial Infarction.

Clin Med Insights Case Rep 2018 13;11:1179547618763356. Epub 2018 Mar 13.

Department of Internal Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.

Uncontrolled diabetes and acute coronary syndrome share a complex dynamic that results in significant ambiguity when interpreting biomarker elevations in this setting. This is concerning because myocardial infarction has been shown to be the most common cause of death in the first 24 hours of admission for uncontrolled diabetes. Literature shows that elevation in cardiac biomarkers in patients with uncontrolled diabetes could be from viral myopericarditis, although a clear clinical significance is still lacking. Read More

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http://dx.doi.org/10.1177/1179547618763356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858608PMC
March 2018
10 Reads

Recurrent Pleural Effusion as a Result of Bilateral Renal Artery Stenosis. Does Renal Revascularization Help?

Clin Med Insights Case Rep 2018 5;11:1179547618761378. Epub 2018 Mar 5.

Department of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.

Renal artery stenosis (RAS) is the leading cause of secondary hypertension. Renal artery stenosis can result in various cardiopulmonary complications mostly through activation of neurohormonal pathways that result in fluid overload and systemic hypertension. We herein describe a 72-year-old man with recurrent rapidly accumulating transudative pleural effusion in a patient with severe bilateral RAS. Read More

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http://dx.doi.org/10.1177/1179547618761378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843098PMC
March 2018
7 Reads

Management of Tizanidine Withdrawal Syndrome: A Case Report.

Clin Med Insights Case Rep 2018 13;11:1179547618758022. Epub 2018 Feb 13.

Pharmacy Department, IDIBELL and Hospital Universitario de Bellvitge, Barcelona, Spain.

Most drugs that act on the central nervous system (CNS) require dose titration to avoid withdrawal syndrome. Tizanidine withdrawal syndrome is caused by adrenergic discharge due to its α-agonist mechanism and is characterized by hypertension, reflex tachycardia, hypertonicity, and anxiety. Although tizanidine withdrawal syndrome is mentioned as a potential side effect of cessation, it is not common and there have been few reports. Read More

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http://dx.doi.org/10.1177/1179547618758022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815413PMC
February 2018
3 Reads

A Rare Presentation of Neuromyelitis Optica Spectrum Disorders.

Clin Med Insights Case Rep 2018 5;11:1179547617752685. Epub 2018 Feb 5.

Internal Medicine Residency Program, St. Mary Medical Center and UCLA, Long Beach, CA, USA.

Neuromyelitis optica spectrum disorders (NMOSDs) are a set of demyelinating disorders that primarily target the optic nerves and the spinal cord. Previously thought to be a subset of multiple sclerosis (MS), now is recognized as a distinct entity. We present a 59-year-old female patient who was admitted for acute upper and lower extremity weakness. Read More

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http://dx.doi.org/10.1177/1179547617752685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802599PMC
February 2018
11 Reads

Same Gene Mutation But Variable Phenotypes in 2 Families With Lynch Syndrome: Two Case Reports and Review of Genotype-Phenotype Correlation.

Clin Med Insights Case Rep 2018 23;11:1179547617753943. Epub 2018 Jan 23.

Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy.

Lynch syndrome is an autosomal dominant syndrome that can be subdivided into Lynch syndrome I, or site-specific colonic cancer, and Lynch syndrome II, or extracolonic cancers, particularly carcinomas of the stomach, endometrium, biliary and pancreatic systems, and urinary tract. Lynch syndrome is associated with point mutations and large rearrangements in DNA MisMatch Repair () genes. This syndrome shows a variable phenotypic expression in people who carry pathogenetic mutations. Read More

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http://dx.doi.org/10.1177/1179547617753943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784535PMC
January 2018
6 Reads

Crizotinib, an Effective Agent in -Rearranged Adenocarcinoma of Lungs: A Case Report.

Clin Med Insights Case Rep 2018 15;11:1179547617749615. Epub 2018 Jan 15.

Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India.

Introduction: rearrangement has recently emerged as a new molecular subtype in non-small-cell lung cancer (NSCLC) and is predominantly found in lung adenocarcinoma compared with other oncogenes such as , or . It has been identified in only 1% to 2% of NSCLC cases.

Case Report: We report a case of 52-year-old man (nonsmoker) with a medical history of allergic rhinitis and bronchial asthma. Read More

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http://dx.doi.org/10.1177/1179547617749615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772496PMC
January 2018
8 Reads

Case Report of a Small Gastric Neuroendocrine Tumor in a Deep Layer of Submucosa With Diagnosis by Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Treatment With Laparoscopic and Endoscopic Cooperative Surgery.

Clin Med Insights Case Rep 2018 10;11:1179547617749226. Epub 2018 Jan 10.

Department of Pathology, Aizu Medical Center, Fukushima Medical University, Fukushima, Japan.

Gastric neuroendocrine tumors (GNETs) are rare lesions characterized by enterochromaffin-like cells of the stomach. Optimal management of GNETs has not yet been definitively determined. Endoscopic resection is approximately recommended for small GNETs associated with hypergastrinemia. Read More

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http://dx.doi.org/10.1177/1179547617749226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768268PMC
January 2018
12 Reads

Very Rare Presentation of Cerebrovascular Accident in 20-Year-Old Man With Familial Mediterranean Fever-Case Report.

Clin Med Insights Case Rep 2018 3;11:1179547617749208. Epub 2018 Jan 3.

Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

Familial Mediterranean fever (FMF) is characterized by recurrent episodes of fever accompanied by serosal, synovial, or cutaneous inflammation. The central nervous system (CNS) is rarely involved in FMF. The CNS involvement includes demyelinating lesions, posterior reversible encephalopathy syndrome, pseudotumor cerebri, optic neuritis, and cerebral vasculitis. Read More

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http://dx.doi.org/10.1177/1179547617749208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757431PMC
January 2018
8 Reads

Case Series: Spontaneous Relapse After Recovery From Peripartum Cardiomyopathy.

Clin Med Insights Case Rep 2017 17;10:1179547617749227. Epub 2017 Dec 17.

Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

Background: Peripartum cardiomyopathy (PPCM) is a distinct type of heart failure with reduced ejection fraction (EF) with variable outcomes. Rates of recovery range from 29% to 72% and mortality rates range from 0% to 25%. In studies, outcomes are often determined at 6 to 12 months following diagnosis, and many of those who recover stop following with cardiology and are lost to follow-up. Read More

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http://dx.doi.org/10.1177/1179547617749227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751909PMC
December 2017
5 Reads

A New Procedure for Wrapped-Negative Pressure Wound Therapy for Congestion After Arterialized Venous Flap Surgery.

Clin Med Insights Case Rep 2017 13;10:1179547617747279. Epub 2017 Dec 13.

Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan.

Negative pressure wound therapy (NPWT) is a method for treating wound. However, there are no case reports using NPWT for treating congestion after arterialized venous flap. Therefore, this study reported favorable outcomes after using a single-use NPWT system for managing congestion. Read More

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http://dx.doi.org/10.1177/1179547617747279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731612PMC
December 2017
14 Reads

The Effects of Astym Therapy® on a Child With Spastic Diplegic Cerebral Palsy.

Clin Med Insights Case Rep 2017 13;10:1179547617746992. Epub 2017 Dec 13.

Physical Therapy Program, University of Findlay, Findlay, OH, USA.

Purpose: Limited research exists regarding use of Astym® therapy with neurologic conditions. The purpose of this case was to describe using Astym therapy in treating spastic diplegic cerebral palsy (CP).

Case Description: A 6-year-old female was treated more than 9 months (36 sessions) for decreased flexibility, muscle weakness, spasticity, and abnormal gait. Read More

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http://dx.doi.org/10.1177/1179547617746992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731617PMC
December 2017
14 Reads

Peritoneal Dialysis and Retroperitoneal Laparoscopic Radical Nephrectomy: A Favorable Experience With a Patient Complicated by Renal Cell Carcinoma.

Clin Med Insights Case Rep 2017 10;10:1179547617746362. Epub 2017 Dec 10.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan.

Peritoneal dialysis (PD) is an accepted modality for managing end-stage kidney disease. We herein report a 75-year-old female patient on chronic PD who was complicated by renal cell carcinoma. She was successfully treated with retroperitoneal laparoscopic radical nephrectomy followed by a prompt resumption of the procedure. Read More

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http://journals.sagepub.com/doi/10.1177/1179547617746362
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http://dx.doi.org/10.1177/1179547617746362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731611PMC
December 2017
20 Reads

Skull Meningioma Associated with Intradural Cyst: A Case Report.

Clin Med Insights Case Rep 2017 2;10:1179547617738231. Epub 2017 Nov 2.

Department of Neurosurgery, Mie University Graduate School of Medicine, Tsu, Japan.

We present the first report of intraosseous meningioma accompanied by intradural cyst formation. A 76-year-old woman had previously undergone breast cancer treatment, so the preoperative diagnosis was metastatic breast cancer. This case reminds us that the possibility of meningioma should be kept in mind in patients with breast cancer, irrespective of neuroimaging findings. Read More

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http://dx.doi.org/10.1177/1179547617738231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672993PMC
November 2017
10 Reads

Successful Surgical Resection of Iatrogenic Antecubital Venous Pseudoaneurysm Following Venipuncture: A 2-Case Report.

Clin Med Insights Case Rep 2017 30;10:1179547617737790. Epub 2017 Oct 30.

Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.

Iatrogenic venous pseudoaneurysm (VP) formation after venipuncture is rare. This report showed 2 cases of VP following venipuncture, and VPs were resected surgically. A 58-year-old woman and a 56-year-old woman developed a soft antecubital mass after blood sampling from the basilic veins. Read More

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http://dx.doi.org/10.1177/1179547617737790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666517PMC
October 2017
9 Reads

A Case of Rare Diffuse Alveolar Hemorrhage and Review of Literature.

Clin Med Insights Case Rep 2017 16;10:1179547617726077. Epub 2017 Aug 16.

Section of Nephrology, Division of Internal Medicine, Department of Clinical and Experimental Medicine, Policlinico Universitario, University of Catania, Catania, Italy.

It is well known that some disorders can cause concomitant kidney dysfunction with lung involvement. These syndromes, characterized by the simultaneous presence of intra-alveolar hemorrhage and acute glomerulonephritis, are caused by numerous and variable disorders. The most frequent are the antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis and Goodpasture syndrome. Read More

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http://dx.doi.org/10.1177/1179547617726077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562341PMC
August 2017
18 Reads

Pitfalls in the Diagnosis and Management of Invasive Pneumococcal Meningoencephalitis - What We Can Learn From a Case.

Clin Med Insights Case Rep 2017 16;10:1179547617725505. Epub 2017 Aug 16.

Medical Intensive Care Units, University Hospital Basel, Basel, Switzerland.

Invasive pneumococcal meningitis is a life-threatening infectious disease affecting the central nervous system. It continues to be the most common type of community-acquired acute bacterial meningitides. Despite advances in neuro-critical care, the case fatality rate remains high. Read More

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http://dx.doi.org/10.1177/1179547617725505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562335PMC
August 2017
36 Reads

Pleuroperitoneal Communication and Ovarian Cancer Complicating Peritoneal Dialysis: A Case Report of a Patient with End-Stage Kidney Disease.

Clin Med Insights Case Rep 2017 16;10:1179547617735818. Epub 2017 Oct 16.

Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.

Peritoneal dialysis has been a widely accepted modality for treating end-stage kidney disease, but a regular dialysis schedule can be seriously disrupted by various comorbid conditions requiring surgical intervention. A 40-year-old woman who had been receiving peritoneal dialysis was sequentially but separately complicated by pleuroperitoneal communication and ovarian cancer. Despite the need for temporary interruption of her peritoneal dialysis schedule, it was successfully resumed after the relevant surgeries for each disease. Read More

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http://dx.doi.org/10.1177/1179547617735818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648088PMC
October 2017
21 Reads