Clin Med Insights Arthritis Musculoskelet Disord 2018 3;11:1179544117751430. Epub 2018 Jan 3.
Department of Anatomy, Paracelsus Medical University, Nuremberg, Germany.
Accumulating evidence demonstrates that complement activation is involved in the pathogenesis of osteoarthritis (OA). However, the intimate complement regulation and cross talk with other signaling pathways in joint-associated tissues remain incompletely understood. Recent insights are summarized and discussed here, to put together a more comprehensive picture of complement involvement in OA pathogenesis. Read More