Clin J Am Soc Nephrol 2017 Sep 18. Epub 2017 Sep 18.
Department of Clinical Pharmacy and Pharmacology and
Background And Objectives: RRT and doubling of serum creatinine are considered the objective hard end points in nephrology intervention trials. Because both are assumed to reflect changes in the filtration capacity of the kidney, drug effects, if present, are attributed to kidney protection. However, decisions to start RRT are not only on the basis of filtration capacity of the kidney, but also on other factors. Read More