3,886 results match your criteria Clinical Journal of the American Society of Nephrology CJASN[Journal]


Inadequate Dietary Potassium and Progression of CKD.

Authors:
Thomas D DuBose

Clin J Am Soc Nephrol 2019 Feb 14. Epub 2019 Feb 14.

Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina; and

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http://dx.doi.org/10.2215/CJN.01020119DOI Listing
February 2019

Central Venous Stenosis, Access Outcome and Survival in Patients undergoing Maintenance Hemodialysis.

Clin J Am Soc Nephrol 2019 Feb 14. Epub 2019 Feb 14.

West London Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare National Health Service Trust, London, UK

Background And Objectives: Central venous catheters have traditionally provided access for urgent hemodialysis, but are also sometimes advocated as an option for older or more comorbid patients. Adverse effects of this type of dialysis access include central venous stenosis, for which the risk factors and consequences are incompletely understood.

Design, Setting, Participants, & Measurements: We conducted two studies within the same population cohort, comprising all patients starting hemodialysis in a single center from January 2006 to December 2013. Read More

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http://dx.doi.org/10.2215/CJN.07010618DOI Listing
February 2019

Urinary Potassium Excretion and Progression of Chronic Kidney Disease.

Clin J Am Soc Nephrol 2019 Feb 14. Epub 2019 Feb 14.

Department of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, Korea;

Background And Objectives: Data on whether low or high urinary potassium excretion is associated with poor kidney outcome have been conflicting. The aim of this study was to clarify the association between urinary potassium excretion and CKD progression.

Design, Setting, Participants, & Measurements: We investigated the relationship between lower urinary potassium excretion and CKD progression and compared three urinary potassium indices among 1821 patients from the Korean Cohort Study for Outcome in Patients with CKD. Read More

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http://dx.doi.org/10.2215/CJN.07820618DOI Listing
February 2019

Removal of Protein-Bound Uremic Toxins during Hemodialysis Using a Binding Competitor.

Clin J Am Soc Nephrol 2019 Feb 12. Epub 2019 Feb 12.

Renal Research Institute, Research Division, New York, New York.

Background And Objectives: Current hemodialysis techniques fail to efficiently remove the protein-bound uremic toxins p-cresyl sulfate and indoxyl sulfate due to their high degree of albumin binding. Ibuprofen, which shares the same primary albumin binding site with p-cresyl sulfate and indoxyl sulfate, can be infused during hemodialysis to displace these toxins, thereby augmenting their removal.

Design, Setting, Participants, & Measurements: We infused 800 mg ibuprofen into the arterial bloodline between minutes 21 and 40 of a conventional 4-hour high-flux hemodialysis treatment. Read More

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http://dx.doi.org/10.2215/CJN.05240418DOI Listing
February 2019

Efficacy and Safety of Imarikiren in Patients with Type 2 Diabetes and Microalbuminuria: A Randomized, Controlled Trial.

Clin J Am Soc Nephrol 2019 Feb 12. Epub 2019 Feb 12.

Takeda Development Center Japan, Takeda Pharmaceutical Company Limited, Osaka, Japan

Background And Objectives: Imarikiren is a novel, potent, and selective direct renin inhibitor that has shown high oral availability during clinical development for the treatment of diabetic nephropathy. We evaluated the efficacy and safety of imarikiren in patients with type 2 diabetes mellitus and microalbuminuria.

Design, Setting, Participants, & Measurements: This was a randomized, multicenter, placebo-controlled, double-blind, phase 2, dose-finding trial. Read More

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http://dx.doi.org/10.2215/CJN.07720618DOI Listing
February 2019

Net Acid Excretion and Urinary Organic Anions in Idiopathic Uric Acid Nephrolithiasis.

Clin J Am Soc Nephrol 2019 Feb 11. Epub 2019 Feb 11.

Department of Internal Medicine,

Background And Objectives: Idiopathic uric acid nephrolithiasis, which is closely associated with obesity and the metabolic syndrome, is increasing in prevalence. Unduly acidic urine pH, the quintessential pathophysiologic feature of this disease, is in part explained by inadequate excretion of the principal urinary buffer ammonium. The role of net acid excretion in the pathogenesis of uric acid nephrolithiasis is incompletely understood. Read More

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http://dx.doi.org/10.2215/CJN.10420818DOI Listing
February 2019
1 Read

Serum Metabolomic Alterations Associated with Proteinuria in CKD.

Clin J Am Soc Nephrol 2019 Feb 7. Epub 2019 Feb 7.

Welch Center for Prevention, Epidemiology, and Clinical Research,

Background And Objectives: Data are scarce on blood metabolite associations with proteinuria, a strong risk factor for adverse kidney outcomes. We sought to investigate associations of proteinuria with serum metabolites identified using untargeted profiling in populations with CKD.

Design, Setting, Participants, & Measurements: Using stored serum samples from the African American Study of Kidney Disease and Hypertension (AASK; =962) and the Modification of Diet in Renal Disease (MDRD) study (=620), two rigorously conducted clinical trials with per-protocol measures of 24-hour proteinuria and GFR, we evaluated cross-sectional associations between urine protein-to-creatinine ratio and 637 known, nondrug metabolites, adjusting for key clinical covariables. Read More

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http://dx.doi.org/10.2215/CJN.10010818DOI Listing
February 2019
1 Read

Hypernatremia.

Authors:
Qi Qian

Clin J Am Soc Nephrol 2019 Feb 6. Epub 2019 Feb 6.

Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic School of Medicine, Rochester, Minnesota

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http://dx.doi.org/10.2215/CJN.12141018DOI Listing
February 2019
1 Read

Enhanced Removal of Protein-Bound Uremic Toxins Using Displacers: Road to Success?

Clin J Am Soc Nephrol 2019 Feb 6. Epub 2019 Feb 6.

Renal Division, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.2215/CJN.00500119DOI Listing
February 2019
1 Read

A Conceptual Framework of Palliative Care across the Continuum of Advanced Kidney Disease.

Clin J Am Soc Nephrol 2019 Feb 6. Epub 2019 Feb 6.

Division of Renal-Electrolyte, Department of General Medicine, Section of Palliative Care and Medical Ethics, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania.

Kidney palliative care is a growing discipline within nephrology. Kidney palliative care specifically addresses the stress and burden of advanced kidney disease through the provision of expert symptom management, caregiver support, and advance care planning with the goal of optimizing quality of life for patients and families. The integration of palliative care principles is necessary to address the multidimensional impact of advanced kidney disease on patients. Read More

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http://dx.doi.org/10.2215/CJN.09330818DOI Listing
February 2019

Kidney Xenotransplantation: Steps toward Clinical Application.

Clin J Am Soc Nephrol 2019 Feb 6. Epub 2019 Feb 6.

Department of Surgery, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.2215/CJN.12471018DOI Listing
February 2019

Differences in Dialysis Center Practices in Determining Hemodialysis Patient Postdialysis Target Weight and Patient Survival and Hospitalizations.

Authors:
Andrew Davenport

Clin J Am Soc Nephrol 2019 Feb 5. Epub 2019 Feb 5.

UCL Department of Nephrology, University College London Centre for Dialysis and Physiology, Royal Free Hospital, London, United Kingdom

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http://dx.doi.org/10.2215/CJN.15181218DOI Listing
February 2019
1 Read

Associations between Hemodialysis Facility Practices to Manage Fluid Volume and Intradialytic Hypotension and Patient Outcomes.

Clin J Am Soc Nephrol 2019 Feb 5. Epub 2019 Feb 5.

Department of Renal Medicine, Heartlands Hospital, Birmingham, UK.

Background And Objectives: Fluid overload and intradialytic hypotension are associated with cardiovascular events and mortality in patients on hemodialysis. We investigated associations between hemodialysis facility practices related to fluid volume and intradialytic hypotension and patient outcomes.

Design, Setting, Participants, & Measurements: Data were analyzed from 10,250 patients in 273 facilities across 12 countries, from phase 4 of the Dialysis Outcomes and Practice Patterns Study (DOPPS; 2009-2012). Read More

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http://dx.doi.org/10.2215/CJN.08240718DOI Listing
February 2019
1 Read

Integrated Care in ESKD: Perspective of a Large Dialysis Organization.

Clin J Am Soc Nephrol 2019 Jan 29. Epub 2019 Jan 29.

Office of the Chief Medical Officer, DaVita, Inc., Denver, Colorado.

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http://dx.doi.org/10.2215/CJN.08300718DOI Listing
January 2019

Integrated Care in ESKD: A Perspective of Nephrologists.

Clin J Am Soc Nephrol 2019 Jan 29. Epub 2019 Jan 29.

Selzman Institute for Kidney Health and Section of Nephrology, Baylor College of Medicine, Houston, Texas; and

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http://dx.doi.org/10.2215/CJN.13081118DOI Listing
January 2019

Integrated Care for People with Kidney Disease: The Perspective of a Nonprofit Dialysis Provider.

Clin J Am Soc Nephrol 2019 Jan 29. Epub 2019 Jan 29.

Division of Nephrology, Tufts Medical Center, Boston, Massachusetts

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http://dx.doi.org/10.2215/CJN.13641118DOI Listing
January 2019
1 Read

Benefits and Barriers to and Desired Outcomes with Exercise in Patients with ESKD.

Clin J Am Soc Nephrol 2019 Jan 29. Epub 2019 Jan 29.

Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; and

Background And Objectives: Patients with ESKD are sedentary. When patient-identified barriers to exercise are addressed, recruitment and retention in exercise trials remain low, suggesting that the trial design may not resonate with them. Therefore, we conducted a survey of patients on dialysis to assess perceived benefits and barriers to exercise and discover preferred outcomes and exercise type by dialysis modality and age in anticipation of designing future randomized, controlled trials. Read More

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http://dx.doi.org/10.2215/CJN.09700818DOI Listing
January 2019
2 Reads

A Patient's View on Exercise and ESKD.

Clin J Am Soc Nephrol 2019 Jan 29. Epub 2019 Jan 29.

Kidney Health Initiative's Patient and Family Partnership Council, Washington, D.C. and

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http://dx.doi.org/10.2215/CJN.00150119DOI Listing
January 2019

Complement Gene Variants and Shiga Toxin-Producing -Associated Hemolytic Uremic Syndrome: Retrospective Genetic and Clinical Study.

Clin J Am Soc Nephrol 2019 01 23. Epub 2019 Jan 23.

Pediatric Nephrology Department, Hôpital Robert Debré, University Paris Diderot, Assistance Publique-Hôpitaux de Paris, Paris, France

Background And Objectives: Inherited complement hyperactivation is critical for the pathogenesis of atypical hemolytic uremic syndrome (HUS) but undetermined in postdiarrheal HUS. Our aim was to investigate complement activation and variants of complement genes, and their association with disease severity in children with Shiga toxin-associated HUS.

Design, Setting, Participants, & Measurements: Determination of complement biomarkers levels and next-generation sequencing for the six susceptibility genes for atypical HUS were performed in 108 children with a clinical diagnosis of post-diarrheal HUS (75 Shiga toxin-positive, and 33 Shiga toxin-negative) and 80 French controls. Read More

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http://dx.doi.org/10.2215/CJN.05830518DOI Listing
January 2019
1 Read

Assessing Clinical Relevance of Uremic Toxins.

Clin J Am Soc Nephrol 2019 Jan 21. Epub 2019 Jan 21.

Division of Nephrology and Hypertension, Department of Medicine, Case Western Reserve University, Cleveland, Ohio

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http://dx.doi.org/10.2215/CJN.14931218DOI Listing
January 2019
1 Read

Trimethylamine -Oxide and Cardiovascular Outcomes in Patients with End-stage Kidney Disease Receiving Maintenance Hemodialysis.

Clin J Am Soc Nephrol 2019 Jan 21. Epub 2019 Jan 21.

Department of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical, Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.

Background And Objectives: Trimethylamine -oxide (TMAO), a compound derived from byproducts of intestinal bacteria, has been shown to accelerate atherosclerosis in rodents. To date, there are conflicting data regarding the association of serum TMAO with cardiovascular outcomes in patients with ESKD, a population exhibiting both high serum TMAO and excessive atherosclerosis.

Design, Setting, Participants, & Measurements: We measured baseline serum TMAO concentrations in a subset of participants (=1243) from the Evaluation of Cinacalcet Hydrochloride Therapy to Lower Cardiovascular Events (EVOLVE) trial and conducted analyses evaluating the association between baseline serum TMAO and cardiovascular outcomes. Read More

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http://dx.doi.org/10.2215/CJN.06190518DOI Listing
January 2019
1 Read

Patient Entrepreneurs to Drive Health Care Innovation for Kidney Disease.

Clin J Am Soc Nephrol 2019 Jan 21. Epub 2019 Jan 21.

Lyfebulb, New York, New York

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http://dx.doi.org/10.2215/CJN.13731118DOI Listing
January 2019

Variability in Cinacalcet Prescription across US Hemodialysis Facilities.

Clin J Am Soc Nephrol 2019 Jan 21. Epub 2019 Jan 21.

Arbor Research Collaborative for Health, Ann Arbor, Michigan.

Background And Objectives: Calcimimetic drugs used to treat secondary hyperparathyroidism are being considered for inclusion in the Medicare ESRD Prospective Payment System bundle after an evaluation period. Understanding of utilization patterns of calcimimetics across dialysis facilities may help align financial incentives with clinical objectives. Our study's purpose was to describe the distribution of cinacalcet prescription across United States hemodialysis facilities and to explore factors that may influence cinacalcet utilization. Read More

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http://dx.doi.org/10.2215/CJN.09550818DOI Listing
January 2019
1 Read

Medication Prescription Patterns for Secondary Hyperparathyroidism: More Questions than Answers.

Clin J Am Soc Nephrol 2019 Jan 21. Epub 2019 Jan 21.

Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts

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http://dx.doi.org/10.2215/CJN.15081218DOI Listing
January 2019
1 Read

Prospective Biopsy-Based Study of Chronic Kidney Disease of Unknown Etiology in Sri Lanka.

Clin J Am Soc Nephrol 2019 Jan 18. Epub 2019 Jan 18.

Kandy Teaching Hospital, Kandy, Sri Lanka.

Background And Objectives: A kidney disease of unknown cause is common in Sri Lanka's lowland (dry) region. Detailed clinical characterizations of patients with biopsy-proven disease are limited, and there is no current consensus on criteria for a noninvasive diagnosis.

Design, Setting, Participants, & Measurements: We designed a prospective study in a major Sri Lankan hospital servicing endemic areas to ascertain pathologic and clinical characteristics of and assess risk factors for primary tubulointerstitial kidney disease. Read More

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http://dx.doi.org/10.2215/CJN.07430618DOI Listing
January 2019
4 Reads
4.613 Impact Factor

Blood Pressure Variability in CKD: Treatable or Hypertension's Homocysteine?

Clin J Am Soc Nephrol 2019 Jan 18. Epub 2019 Jan 18.

Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, Minnesota

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http://dx.doi.org/10.2215/CJN.14991218DOI Listing
January 2019
1 Read

Buttonhole versus Stepladder Cannulation for Home Hemodialysis: A Multicenter, Randomized, Pilot Trial.

Clin J Am Soc Nephrol 2019 Jan 18. Epub 2019 Jan 18.

Ottawa Hospital, Ottawa, Ontario, Canada;

Background And Objectives: Canadian home hemodialysis guidelines highlight the potential differences in complications associated with arteriovenous fistula (AVF) cannulation technique as a research priority. Our primary objective was to determine the feasibility of randomizing patients with ESKD training for home hemodialysis to buttonhole versus stepladder cannulation of the AVF. Secondary objectives included training time, pain with needling, complications, and cost by cannulation technique. Read More

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http://dx.doi.org/10.2215/CJN.08310718DOI Listing
January 2019
2 Reads
4.613 Impact Factor

Integration of Genetic Testing and Pathology for the Diagnosis of Adults with FSGS.

Clin J Am Soc Nephrol 2019 Jan 15. Epub 2019 Jan 15.

Division of Nephrology and

Background And Objectives: FSGS and nephrotic syndrome studies have shown that single gene causes are more likely to be found in pediatric cases than adults. Consequently, many studies have examined limited gene panels in largely pediatric cohorts.

Design, Setting, Participants, & Measurements: Whole-exome sequencing was performed in adults with FSGS diagnosed between 1976 and 2017 in the Toronto GN Registry. Read More

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.08750718
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http://dx.doi.org/10.2215/CJN.08750718DOI Listing
January 2019
11 Reads

Mentorship in the Digital Age: Nephrology Social Media Collective Internship.

Clin J Am Soc Nephrol 2019 Jan 15. Epub 2019 Jan 15.

Division of Nephrology, Department of Medicine, Oakland University William Beaumont School of Medicine, Auburn Hills, Michigan.

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http://dx.doi.org/10.2215/CJN.09970818DOI Listing
January 2019
1 Read

Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy.

Clin J Am Soc Nephrol 2019 Jan 11. Epub 2019 Jan 11.

Division of Renal Diseases and Hypertension, University of Minnesota, Minneapolis, Minnesota

IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved therapies. A challenge for evaluating treatments for IgAN is the usual long time course for progression to ESKD. The aim of this Kidney Health Initiative project was to identify surrogate end points that could serve as reliable predictors of a treatment's effect on long-term kidney outcomes in IgAN and be used as a basis for approval. Read More

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.08600718
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http://dx.doi.org/10.2215/CJN.08600718DOI Listing
January 2019
6 Reads

Clinical Outcomes of Failing to Dose-Reduce Cephalosporin Antibiotics in Older Adults with CKD.

Clin J Am Soc Nephrol 2019 Jan 10. Epub 2019 Jan 10.

Institute for Clinical Evaluative Sciences, Ontario, Canada;

Background And Objectives: Current dosing recommendations for cephalosporin antibiotics are on the basis of pharmacokinetic studies and are frequently ignored in practice. This study was undertaken to investigate the clinical outcomes of failing to dose-reduce cephalosporin antibiotics in CKD.

Design, Setting, Participants, & Measurements: Retrospective cohort study conducted in Ontario, Canada using linked population-based health care databases. Read More

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http://dx.doi.org/10.2215/CJN.10710918DOI Listing
January 2019
1 Read

Correction.

Authors:

Clin J Am Soc Nephrol 2019 Jan 10. Epub 2019 Jan 10.

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http://dx.doi.org/10.2215/CJN.13671118DOI Listing
January 2019
1 Read

Patients,' Nephrologists,' and Predicted Estimations of ESKD Risk Compared with 2-Year Incidence of ESKD.

Clin J Am Soc Nephrol 2019 Jan 10. Epub 2019 Jan 10.

Division of Nephrology-Hypertension, University of California, San Diego, La Jolla, California;

Background And Objectives: The rate of progression to ESKD is variable, and prognostic information helps patients and physicians plan for future ESKD. We assessed the estimations of ESKD risk of patients with CKD and physicians and compared them with risk calculators and outcomes at 2 years.

Design, Setting, Participants, & Measurements: This prospective observational study assessed 257 adult patients with CKD stages 3-5 and their nephrologists at University of California, San Diego and Veterans Affairs San Diego CKD clinics. Read More

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http://dx.doi.org/10.2215/CJN.07970718DOI Listing
January 2019
1 Read

The Case for a Bariatric-Centered Approach to Chronic Kidney Disease Care.

Authors:
Allon N Friedman

Clin J Am Soc Nephrol 2019 Jan 10. Epub 2019 Jan 10.

Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana

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http://dx.doi.org/10.2215/CJN.12061018DOI Listing
January 2019
1 Read

The Use of Selected Urine Chemistries in the Diagnosis of Kidney Disorders.

Clin J Am Soc Nephrol 2019 Jan 9. Epub 2019 Jan 9.

Department of Internal Medicine, University of California, Los Angeles School of Medicine, Los Angeles, California.

Urinary chemistries vary widely in both health and disease and are affected by diet, volume status, medications, and disease states. When properly examined, these tests provide important insight into the mechanism and therapy of various clinical disorders that are first detected by abnormalities in plasma chemistries. These tests cannot be interpreted in isolation, but instead require knowledge of key clinical information, such as medications, physical examination, and plasma chemistries, to include kidney function. Read More

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http://dx.doi.org/10.2215/CJN.10330818DOI Listing
January 2019
10 Reads

MicroRNAs in Acute Kidney Injury and Kidney Transplantation.

Clin J Am Soc Nephrol 2019 Jan 2. Epub 2019 Jan 2.

Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Wilrijk, Belgium;

MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level. They are involved in intercellular communication and crosstalk between different organs. As key regulators of homeostasis, their dysregulation underlies several morbidities including kidney disease. Read More

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http://dx.doi.org/10.2215/CJN.08020718DOI Listing
January 2019
1 Read

Blood Pressure Variability, Mortality, and Cardiovascular Outcomes in Chronic Kidney Disease Patients.

Clin J Am Soc Nephrol 2019 Jan 2. Epub 2019 Jan 2.

Division of Nephrology, University of Campania "Luigi Vanvitelli," Naples, Italy

Background And Objectives: Short-term BP variability (derived from 24-hour ambulatory BP monitoring) and long-term BP variability (from clinic visit to clinic visit) are directly related to risk for cardiovascular events, but these relationships have been scarcely investigated in patients with CKD, and their prognostic value in this population is unknown.

Design, Setting, Participants, & Measurements: In a cohort of 402 patients with CKD, we assessed associations of short- and long-term systolic BP variability with a composite end point of death or cardiovascular event. Variability was defined as the standard deviation of observed BP measurements. Read More

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http://dx.doi.org/10.2215/CJN.04030318DOI Listing
January 2019
1 Read

Demystifying the Benefits and Harms of Anticoagulation for Atrial Fibrillation in Chronic Kidney Disease.

Clin J Am Soc Nephrol 2019 Jan 28;14(1):125-136. Epub 2018 Dec 28.

Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Patients with CKD represent a vulnerable population where the risks of atrial fibrillation, ischemic stroke, and bleeding are all heightened. Although large randomized, controlled trials in the general population clearly demonstrate that the benefits of warfarin and direct-acting oral anticoagulants outweigh the risks of bleeding, no such studies have been conducted in patients when their creatinine clearance falls below 25-30 ml/min. Without randomized, controlled trial data, the role of anticoagulation in patients with CKD with atrial fibrillation remains unclear and our practice is informed by a growing body of imperfect literature such as observational and pharmacokinetic studies. Read More

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http://dx.doi.org/10.2215/CJN.06430518DOI Listing
January 2019
1 Read

Screening Transplant Waitlist Candidates for Coronary Artery Disease.

Authors:
John S Gill

Clin J Am Soc Nephrol 2019 Jan 28;14(1):112-114. Epub 2018 Dec 28.

Division of Nephrology, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.2215/CJN.10510918DOI Listing
January 2019
1 Read

Commentary on "Demystifying the Benefits and Harms of Anticoagulation for Atrial Fibrillation in CKD".

Clin J Am Soc Nephrol 2019 Jan 28;14(1):137-138. Epub 2018 Dec 28.

Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland

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http://dx.doi.org/10.2215/CJN.13431118DOI Listing
January 2019
1 Read

Patterns of Beverages Consumed and Risk of Incident Kidney Disease.

Clin J Am Soc Nephrol 2019 Jan 27;14(1):49-56. Epub 2018 Dec 27.

Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi.

Background And Objectives: Selected beverages, such as sugar-sweetened beverages, have been reported to influence kidney disease risk, although previous studies have been inconsistent. Further research is necessary to comprehensively evaluate all types of beverages in association with CKD risk to better inform dietary guidelines.

Design, Setting, Participants, & Measurements: We conducted a prospective analysis in the Jackson Heart Study, a cohort of black men and women in Jackson, Mississippi. Read More

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.06380518
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http://dx.doi.org/10.2215/CJN.06380518DOI Listing
January 2019
7 Reads

Diet and Risk for Developing Kidney Disease.

Authors:
Duane Sunwold

Clin J Am Soc Nephrol 2019 Jan 27;14(1):1-2. Epub 2018 Dec 27.

Inland Northwest Culinary Academy, Spokane Community College, Spokane, Washington

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http://dx.doi.org/10.2215/CJN.13601118DOI Listing
January 2019
1 Read

The Millennial Physician and the Obesity Epidemic: A Tale of Sugar-Sweetened Beverages.

Clin J Am Soc Nephrol 2019 Jan 27;14(1):4-6. Epub 2018 Dec 27.

Department of Public Health Sciences Loyola University Chicago, Maywood, Illinois.

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http://dx.doi.org/10.2215/CJN.13851118DOI Listing
January 2019
1 Read

Plant-Based Diets in CKD.

Clin J Am Soc Nephrol 2019 Jan 26;14(1):141-143. Epub 2018 Dec 26.

Department of Nutrition Science, Purdue University, West Lafayette, Indiana; and.

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http://dx.doi.org/10.2215/CJN.08960718DOI Listing
January 2019
2 Reads

Patient Priorities for Research Involving Peritoneal Dialysis.

Authors:
Jonathan Haydak

Clin J Am Soc Nephrol 2019 Jan 20;14(1). Epub 2018 Dec 20.

Department of Chemical Engineering, Georgia Institute of Technology College of Engineering, Atlanta, Georgia

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http://dx.doi.org/10.2215/CJN.13621118DOI Listing
January 2019
1 Read

Patient and Caregiver Priorities for Outcomes in Peritoneal Dialysis: Multinational Nominal Group Technique Study.

Clin J Am Soc Nephrol 2019 Jan 20;14(1):74-83. Epub 2018 Dec 20.

Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia.

Background And Objectives: The absence of accepted patient-centered outcomes in research can limit shared decision-making in peritoneal dialysis (PD), particularly because PD-related treatments can be associated with mortality, technique failure, and complications that can impair quality of life. We aimed to identify patient and caregiver priorities for outcomes in PD, and to describe the reasons for their choices.

Design, Setting, Participants, & Measurements: Patients on PD and their caregivers were purposively sampled from nine dialysis units across Australia, the United States, and Hong Kong. Read More

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.05380518
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http://dx.doi.org/10.2215/CJN.05380518DOI Listing
January 2019
6 Reads

Variability of Two Metabolomic Platforms in CKD.

Clin J Am Soc Nephrol 2019 Jan 20;14(1):40-48. Epub 2018 Dec 20.

Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland;

Background And Objectives: Nontargeted metabolomics can measure thousands of low-molecular-weight biochemicals, but important gaps limit its utility for biomarker discovery in CKD. These include the need to characterize technical and intraperson analyte variation, to pool data across platforms, and to outline analyte relationships with eGFR.

Design, Setting, Participants, & Measurements: Plasma samples from 49 individuals with CKD (eGFR<60 ml/min per 1. Read More

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http://dx.doi.org/10.2215/CJN.07070618DOI Listing
January 2019
1 Read

Correction.

Authors:

Clin J Am Soc Nephrol 2018 Dec 20. Epub 2018 Dec 20.

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http://dx.doi.org/10.2215/CJN.13901118DOI Listing
December 2018
1 Read

Diuretic use in incident ESKD: Are we out of the loop?

Clin J Am Soc Nephrol 2019 Jan 19;14(1):13-15. Epub 2018 Dec 19.

Kidney Research Institute, Division of Nephrology, University of Washington, Seattle, Washington

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http://cjasn.asnjournals.org/lookup/doi/10.2215/CJN.13361118
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http://dx.doi.org/10.2215/CJN.13361118DOI Listing
January 2019
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Association of Continuation of Loop Diuretics at Hemodialysis Initiation with Clinical Outcomes.

Clin J Am Soc Nephrol 2019 Jan 19;14(1):95-102. Epub 2018 Dec 19.

Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina School of Medicine, University of North Carolina Kidney Center, Chapel Hill, North Carolina; and.

Background And Objectives: Loop diuretics are commonly used to manage nondialysis-dependent CKD. Despite benefits of augmented urine output, loop diuretics are often discontinued after dialysis initiation. Here, we assessed the association of the early decision to continue loop diuretics at hemodialysis start with clinical outcomes during the first year of dialysis. Read More

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http://dx.doi.org/10.2215/CJN.05080418DOI Listing
January 2019
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