Clin Intensive Care 1995 ;6(2):62-71
Klinik für Anaesthesiologie und operative Intensivmedizin, Virchow Klinikum, Medizinische Fakultät, Humboldt-Universität, Berlin, Germany.
Despite more than 25 years of extensive research the mortality of ARDS patients remains high. Besides the often deleterious course of the underlying disease, another reason for this high mortality lies in the aggressive ventilatory regimen which is required to maintain arterial blood gases in a more or less normal range. Therapeutic methods which are used to reduce iatrogenic damage to the lungs are pressure controlled ventilation with permissive hypercapnia, differential lung ventilation, positioning therapy, dehydration, and extracorporeal gas exchange with membrane lungs. Read More