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    1217 results match your criteria Clinical Implant Dentistry and Related Research [Journal]

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    Lnc-NTF3-5 promotes osteogenic differentiation of maxillary sinus membrane stem cells via sponging miR-93-3p.
    Clin Implant Dent Relat Res 2017 Nov 6. Epub 2017 Nov 6.
    Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
    Background: The function and the mechanism of long non-coding RNAs (lncRNAs) on the osteogenic differentiation of maxillary sinus membrane stem cells (MSMSCs) remain largely unknown.

    Materials And Methods: The expression of lnc-NTF3-5 and Runt-related transcription factor 2 (RUNX2), Osterix (OSX), and Alkaline Phosphatase (ALP) was examined by quantitative real-time PCR (qRT-PCR) in MSMSCs during the process osteogenic differentiation. Then the function of lnc-NTF3-5 was evaluated by loss- and gain-of-function techniques, as well as qRT-PCR, western blot, and Alizarin Red staining. Read More

    Bioactive treatments in bone grafts for implant-based rehabilitation: Systematic review and meta-analysis.
    Clin Implant Dent Relat Res 2017 Nov 6. Epub 2017 Nov 6.
    Department of Restorative Dentistry, Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, RS, Brazil.
    Background: The use of bioactive proteins, such as rhBMP-2, may improve bone regeneration in oral and maxillofacial surgery.

    Purpose: Analyze the effect of using bioactive proteins for bone regeneration in implant-based rehabilitation.

    Materials And Methods: Seven databases were screened. Read More

    Immediately restored full arch-fixed prosthesis on implants placed in both healed and fresh extraction sockets after computer-planned flapless guided surgery. A 3-year follow-up study.
    Clin Implant Dent Relat Res 2017 Oct 29. Epub 2017 Oct 29.
    Oral Surgery Department, Barts and The London School of Medicine and Dentistry, London, UK.
    Background: The treatment of patients by the use of immediate implant placement in post-extractive site is a challenging procedure.

    Purpose: A 3-year clinical and radiological study of post-extractive implants placed using flapless guided surgery and immediately functioning.

    Materials And Methods: Thirty-two patients (23 females and 9 males), aged between 44 and 73 years (a mean age of 59. Read More

    Bar versus ball attachments for implant-supported overdentures in complete edentulism: A systematic review.
    Clin Implant Dent Relat Res 2017 Oct 25. Epub 2017 Oct 25.
    Department of Obstetrics and Gynaecology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
    Background: Implant-supported overdenture is one of the most predictable treatment options used in complete edentulism. However, differences have been reported between bar and ball attachments used to retain overdentures in terms of patient satisfaction and prosthesis retention.

    Purpose: The purpose of this study is to compare the effectiveness of bar and ball attachments for conventionally loaded implant-supported overdentures in completely edentulous patients to improve patient satisfaction and prosthesis retention. Read More

    CyPA and Emmprin play a role in peri-implantitis.
    Clin Implant Dent Relat Res 2017 Oct 22. Epub 2017 Oct 22.
    Department of Prosthodontics, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, PR China.
    Background: Cyclophilin A (CyPA) and Emmprin play important roles in peri-implantitis. However, their roles in the diagnosis and treatment of the disease are still unclear.

    Purpose: The aim of this split-mouth animal study was to describe variable trends of biomarkers during the progression of peri-implantitis and to define relationships among CyPA, Emmprin, and peri-implantitis. Read More

    Radiographic and clinical outcomes of rooted, platform-switched, microthreaded implants with a sandblasted, large-grid, and acid-etched surface: A 5-year prospective study.
    Clin Implant Dent Relat Res 2017 Oct 20. Epub 2017 Oct 20.
    Department of Stomatology, Key Lab of Oral Clinical Medicine, the Affiliated Hospital of Qingdao University, College of Stomatology, Qingdao University, Qingdao, China.
    Background: There is no data available on the long-term outcomes of a rooted, platform-switched, microthreaded implant with a sandblasted, large-grid, and acid-etched surface.

    Purpose: This prospective, longitudinal study evaluated the clinical and radiographic outcomes of rooted, platform-switched, microthreaded and sandblasted, large-grid, and acid-etched (SLA) surface implants for 5 years.

    Materials And Methods: Sixty implants were placed in sixty patients with partially edentulous maxillae or mandibles. Read More

    A prospective randomized controlled trial of the two-window technique without membrane versus the solo-window technique with membrane over the osteotomy window for maxillary sinus augmentation.
    Clin Implant Dent Relat Res 2017 Oct 16. Epub 2017 Oct 16.
    4th Division, Peking University School and Hospital of Stomatology, Beijing, China.
    Background: Maturation of the grafted volume after lateral sinus elevation is crucial for the long-term survival of dental implants.

    Purpose: To compare endo-sinus histomorphometric bone formation between the solo- and two-window maxillary sinus augmentation techniques with or without membrane coverage for the rehabilitation of multiple missing posterior teeth.

    Materials And Methods: Patients with severely atrophic posterior maxillae were randomized to receive lateral sinus floor elevation via the solo-window technique with membrane coverage (Control Group) or the two-window technique without coverage (Test Group). Read More

    A prospective, split-mouth study comparing tilted implants with angulated connection versus conventional implants with angulated abutment.
    Clin Implant Dent Relat Res 2017 Oct 16. Epub 2017 Oct 16.
    Department of Periodontology, Oral Implantology, Removable and Implant Prosthetics, Faculty of Medicine and Health Sciences, Ghent University, Gent, Belgium.
    Background: An angulation of the implant connection could overcome the problems related to angulated abutments.

    Purpose: This study compares conventional implants with angulated abutment to tilted implants with an angulated connection.

    Materials And Methods: Twenty patients were treated in the edentulous mandible. Read More

    Morphometric and histologic characterization of alveolar bone from hypertensive patients.
    Clin Implant Dent Relat Res 2017 Oct 16. Epub 2017 Oct 16.
    Division of Anatomy, Department of Basic Science, Araçatuba Dental School, UNESP-Universidade Estadual Paulista "Júlio de Mesquita Filho", Araçatuba, São Paulo, Brazil.
    Background: Hypertension is considered a risk factor in implant dentistry but the underlying reasons remain unclear. It may be that hypertension has a negative impact on the local bone quality.

    Purpose: Here we evaluated the structural and histological parameters of bone collected from hypertensive patients treated by antagonists of the renin-angiotensin system, and of bone collected from normotensive patients. Read More

    The influence of crown-to-implant ratio on marginal bone levels around splinted short dental implants: A radiological and clincial short term analysis.
    Clin Implant Dent Relat Res 2017 Oct 12. Epub 2017 Oct 12.
    Oral Surgeon, Academy of Oral Implantology, Lazarettgasse 19/DG, 1090 Vienna, Austria.
    Background: The amount of marginal bone resorption around dental implants is considered to have a significant impact on implant stability as well as implant survival rates.

    Purpose: The aim of this prospective study was to investigate the influence of prosthetic as well as patient specific factors on marginal bone loss around short dental implants.

    Materials And Methods: Seventy-six implants, which supported splinted crowns were included for investigation. Read More

    Continuous eruption of maxillary teeth and changes in clinical crown length: A 10-year longitudinal study in adult women.
    Clin Implant Dent Relat Res 2017 Oct 5. Epub 2017 Oct 5.
    Department of Orthodontics, University of Geneva, Geneva, Switzerland.
    Background: Continuous physiologic eruption of teeth may become a main aesthetic issue for implants inserted in the maxillary anterior region.

    Purpose: To study maxillary tooth vertical changes during a 10 years period by 3-dimensional superimposition of digital dental casts.

    Material And Methods: Alginate impressions were taken at both baseline and at the 10-year follow-up in a sample of 24 adult Swedish women (average age of 48 years at T0). Read More

    Cost minimization analysis of a long-term randomized clinical trial of patients treated with immediately loaded implant-supported fixed prosthesis.
    Clin Implant Dent Relat Res 2017 Sep 21. Epub 2017 Sep 21.
    Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada.
    Purpose: To document the long-term costs from a randomized controlled clinical trial (RCT) on edentulous patients treated with mandibular 4-implant-supported fixed prosthesis and two loading protocols.

    Methods: Taking the perspective of the individual patient, costs associated with treatment, complications, and patients' time from 18 patients who received an immediate-loading protocol and 21 patients treated with a conventional loading protocol were compared over 10 years of observation. All costs are in Canadian dollars and discounted to the RCT base year of 2006 at a rate of 1. Read More

    A comparative study of encode protocol versus conventional protocol for restoring single implants: One-year prospective randomized controlled clinical trial.
    Clin Implant Dent Relat Res 2017 Sep 21. Epub 2017 Sep 21.
    Melbourne Dental School, Melbourne University, 720 Swanston Street, Melbourne, Victoria 3010, Australia.
    Background: The Encode protocol (Biomet 3i, Palm Beach Gardens, Fla) has been proposed as a simplified implant restoration protocol.

    Purpose: To compare the 1-year clinical outcome of the Encode and conventional protocols for restoring single implants.

    Materials And Methods: Forty-seven implants were inserted in 44 patients. Read More

    Long-term stable vertical bone regeneration after sinus floor elevation and simultaneous implant placement with and without grafting.
    Clin Implant Dent Relat Res 2017 Sep 21. Epub 2017 Sep 21.
    Odontology Clinic, Catholic University Sacro Cuore, Rome, Italy.
    Background: Less invasive surgical approaches to regenerate bone intra-sinus and allow long-term functional implant stability are needed.

    Purpose: To evaluate long-term vertical bone regeneration after sinus floor elevation and simultaneous implant placement with and without bone grafting.

    Methods: Vertical bone gains (VBG) post-sinus elevation, with and without grafting, were evaluated in thirty individuals presenting an average residual bone height (RBH) of 4. Read More

    Evaluation of volumetric dimensional changes in posterior extraction sites with and without ARP using a novel imaging device.
    Clin Implant Dent Relat Res 2017 Sep 14. Epub 2017 Sep 14.
    Department of Medicine, Surgery and Dentistry "Schola Medica Salernitana", University of Salerno, Via S. Allende, 84081 Baronissi (Salerno).
    Background: Alveolar ridge volume loss may be minimized when postextraction sockets are filled by bone substitutes.

    Purpose: The aim of the study was to measure the effect of alveolar ridge preservation (ARP) in maintaining the external contour of the ridge after fresh socket grafting with or without particulate anorganic bovine bone mineral (BBM) and resorbable barrier covering.

    Materials And Methods: In the present controlled study, patients subjected to single-tooth extraction were allocated to 2 groups: postextraction sockets grafted with bovine bone mineral (bbm), and naturally healing sockets (nat). Read More

    A retro-prospective effectiveness study on 3448 implant operations at one referral clinic: A multifactorial analysis. Part I: Clinical factors associated to early implant failures.
    Clin Implant Dent Relat Res 2017 Sep 8. Epub 2017 Sep 8.
    Department of Prosthetic Dentistry/Dental Materials Science, Institute of Odontology, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
    Background: Limited numbers of large effectiveness studies on routine dental implant treatment are available in the literature.

    Purpose: To report retro-prospective data on prevalence of early implant failures in a large number of routine patients/operations at 1 referral clinic.

    Materials And Methods: A total of 2848 patients were consecutively provided with 9582 implants with an anodized surface (Nobel Biocare AB) during 3448 implant operations between 2003 and 2011. Read More

    A retro-prospective effectiveness study on 3448 implant operations at one referral clinic: A multifactorial analysis. Part II: Clinical factors associated to peri-implantitis surgery and late implant failures.
    Clin Implant Dent Relat Res 2017 Sep 8. Epub 2017 Sep 8.
    Department of Prosthetic Dentistry/Dental Materials Science, Institute of Odontology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.
    Background: Little knowledge is available on implant treatment in large effectiveness studies in routine practice.

    Purpose: To report retro-prospective data on prevalence of peri-implantitis surgery and late implant failures in a large number of routine patients at 1 referral clinic.

    Materials And Methods: Altogether 9582 implants with an anodized surface (Nobel Biocare AB) were consecutively placed between 2003 and 2011 and followed-up to end of 2015. Read More

    Assessment of the effectiveness of platelet rich fibrin in the treatment of Schneiderian membrane perforation.
    Clin Implant Dent Relat Res 2017 Aug 30. Epub 2017 Aug 30.
    Department of Medical Pathology, Bülent Ecevit University School of Medicine, Zonguldak, Turkey.
    Background: The objective of this study is to evaluate the effect of Platelet rich fibrin (PRF) treatment of maxillary sinus membrane perforation on bone formation and new vascular supply and the success of dental implant survival rate.

    Methods: The dataset for this retrospective study consists of patients who received sinus augmentation using the lateral wall technique. A total of 16 patients (20 sinuses) the patients without sinus membrane perforation (10 maxiller sinus area with sinus floor augmentation) and with Schneiderian perforation (10 maxiller sinus area repairing with PRF and augmented sinus floor area) were included in this study. Read More

    Survival rate of titanium-zirconium narrow diameter dental implants versus commercially pure titanium narrow diameter dental implants: A systematic review.
    Clin Implant Dent Relat Res 2017 Aug 29. Epub 2017 Aug 29.
    Department of Prosthodontics, University of Sao Paulo, School of Dentistry, Sao Paulo, Brazil.
    Background: Despite the existence of several studies validating the use of narrow diameter implants, most of them are based on pure Ti alloys. There is few clinical evidence of the success of TiZr narrow diameter implants (TiZr NDIs) regarding survival rate (SR) and marginal bone loss (MLB).

    Purpose: The aim of this review was to systematically assess SR, as well as MBL of TiZr NDIs compared to commercially pure titanium narrow diameter implants (cpTi NDIs). Read More

    Long-term evaluation of osteotome sinus floor elevation and simultaneous placement of implants without bone grafts: 10-Year radiographic and clinical follow-up.
    Clin Implant Dent Relat Res 2017 Aug 29. Epub 2017 Aug 29.
    Department of Oral and Maxillofacial Surgery, Linköping University Hospital, Linköping, Sweden.
    Background: Insertion of an implant in the edentulous posterior maxilla is a challenging procedure because of poor bone quality and increased pneumatization of the maxillary sinus after tooth extraction. To increase the amount of bone, several surgical bone grafting techniques have been used-with considerable morbidity for patients. Osteotome sinus floor elevation (OSFE) is a less invasive technique. Read More

    Transcrestal sinus floor augmentation with immediate implant placement applied in three types of fresh extraction sockets: A clinical prospective study with 1-year follow-up.
    Clin Implant Dent Relat Res 2017 Aug 29. Epub 2017 Aug 29.
    State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
    Background: Immediate implant insertion and transcrestal sinus augmentation both can provide a lot of advantages for patients and clinicians.

    Objective: This prospective study aims to verify the use of a modified technique for immediate implant insertion simultaneously with sinus augmentation in different types of sockets.

    Materials And Methods: Thirty-seven patients were recruited for the clinical study and were divided into 3 groups according to the relationship of their maxillary molar roots and sinus floor: group 1 with none of the teeth roots contacts sinus floor; group 2 as at least 1 teeth root contacting sinus floor, but no root is observed penetrating into sinus cavity; group 3 with at least 1 teeth root penetrating into sinus cavity. Read More

    One-piece internal zirconia abutments for single-tooth restorations on narrow and regular diameter implants: A 5-year prospective follow-up study.
    Clin Implant Dent Relat Res 2017 Oct 9;19(5):916-925. Epub 2017 Aug 9.
    Department of Prosthetic Dentistry and Oral Function, Faculty of Dentistry, Institute of Clinical Dentistry, University of Oslo, Oslo, Norway.
    Background: Studies have reported an increased risk for fractures of zirconia abutments compared with titanium abutments.

    Purpose: The aim of this study was to evaluate single-tooth implant restorations with one-piece yttria-stabilized internal zirconia abutments on narrow and regular diameter implants up to 6 years after insertion.

    Material And Methods: This study comprises 52 consecutively treated patients, with a median age of 19 years. Read More

    Biomechanical behavior of titanium and zirconia frameworks for implant-supported full-arch fixed dental prosthesis.
    Clin Implant Dent Relat Res 2017 Oct 2;19(5):860-866. Epub 2017 Aug 2.
    Department of Dental Materials and Prosthodontics, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil.
    Background: The biomechanical behavior of implant-supported titanium and zirconia full-arch fixed dental prosthesis (FAFDP) frameworks require further investigation.

    Purpose: Strains transferred by implant-supported titanium (Ti) and zirconia (Zr) FAFDP frameworks were analyzed.

    Materials And Methods: Maxillary 14-unit FAFDPs supported by 6 implants and 12-unit FAFDPs supported by 4 implants were tested. Read More

    Measurement of the zygomatic region for the optimal placement of quad zygomatic implants.
    Clin Implant Dent Relat Res 2017 Oct 1;19(5):841-848. Epub 2017 Aug 1.
    Department of Oral-Maxillofacial Implantology, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200011, China.
    Background: The zygomatic implant is suggested to be placed in zygomatic areas with the largest thickness, but regions to obtain the largest bone-to-implant contact (BIC) were unknown.

    Purpose: To identify the zygomatic regions for placing quad zygomatic implants that obtain the largest BIC.

    Materials And Methods: The zygomatic thicknesses of 300 zygomata were measured at total 12 points on the superior, middle, and inferior areas on the 3-dimensional reconstruction images. Read More

    Comparison of marginal bone loss and implant success between axial and tilted implants in maxillary All-on-4 treatment concept rehabilitations after 5 years of follow-up.
    Clin Implant Dent Relat Res 2017 Oct 1;19(5):849-859. Epub 2017 Aug 1.
    Oral Surgery Department, Maló Clinic, Lisbon, Portugal.
    Background: There is need for more scientific and clinical information on longer-term outcomes of tilted implants compared to implants inserted in an axial position.

    Purpose: Comparison of marginal bone loss and implant success after a 5-year follow-up between axial and tilted implants inserted for full-arch maxillary rehabilitation.

    Material And Methods: The retrospective clinical study included 891 patients with 3564 maxillary implants rehabilitated according to the All-on-4 treatment concept. Read More

    Comparison between mineralized cancellous bone allograft and an alloplast material for sinus augmentation: A split mouth histomorphometric study.
    Clin Implant Dent Relat Res 2017 Oct 27;19(5):812-820. Epub 2017 Jul 27.
    Department of Periodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
    Background: Several grafting materials have been used in sinus augmentation procedures including autogenous bone, demineralized freeze-dried bone, hydroxyapatite, β-tricalcium phosphate, anorganic deproteinized bovine bone, and combination of these and others. Yet, the issue of the optimal graft material for sinus floor augmentation is controversial.

    Purpose: This prospective, randomized split-mouth study was undertaken to histomorphometrically compare a biphasic calcium phosphate (BCP) alloplastic bone substitute and a human bone mineral allograft (freeze-dried bone allograft, FDBA) in patients undergoing bilateral maxillary lateral sinus floor augmentation. Read More

    Evaluation of complication rates and vertical bone gain after guided bone regeneration with non-resorbable membranes versus titanium meshes and resorbable membranes. A randomized clinical trial.
    Clin Implant Dent Relat Res 2017 Oct 26;19(5):821-832. Epub 2017 Jul 26.
    Unit of Oral and Maxillofacial Surgery, Department of Biomedical and Neuromotor Science (DIBINEM), Alma Mater Studiorum - University of Bologna, Bologna, Italy.
    Background: The partial edentulous posterior mandible is often a challenge area that requires a bone reconstructive surgery for implants placement.

    Purpose: This RCT was aimed to evaluate complications rate and vertical bone gain after Guided Bone Regeneration (GBR) with dense non-resorbable d-PTFE titanium-reinforced membranes (Group A) versus titanium meshes covered by cross-linked collagen membranes (Group B).

    Material And Methods: 40 partially edentulous patients with atrophic posterior mandible, were randomly divided into two study group: 20 patients were treated with one stage GBR by means of non-resorbable d-PTFE titanium-reinforced membranes (Group A); and 20 patients, by means of titanium mesh covered by cross-linked collagen membranes (Group B). Read More

    Histologic and histomorphometric assessment of sinus-floor augmentation with beta-tricalcium phosphate alone or in combination with pure-platelet-rich plasma or platelet-rich fibrin: A randomized clinical trial.
    Clin Implant Dent Relat Res 2017 Oct 26;19(5):959-967. Epub 2017 Jul 26.
    Department of Histology and Embryology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
    Background: The potential effects of adding pure platelet-rich plasma (P-PRP) or platelet-rich fibrin (PRF) to beta-tricalcium phosphate (β-TCP) graft substitute on bone formation and regeneration after maxillary sinus-floor elevation remains unclear.

    Purpose: To compare the histologic and histomorphometric outcomes of maxillary sinus-floor augmentation among β-TCP alone, P-PRP-mixed β-TCP, and PRF-mixed β-TCP.

    Material And Methods: In this randomized clinical trial, elevated sinus cavities were grafted with β-TCP (the control group), P-PRP-mixed β-TCP (the P-PRP group), and PRF-mixed β-TCP (PRF group). Read More

    Dimensional changes of the maxillary sinus following tooth extraction in the posterior maxilla with and without socket preservation.
    Clin Implant Dent Relat Res 2017 Oct 26;19(5):952-958. Epub 2017 Jul 26.
    Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel.
    Background: Sinus pneumatization is commonly observed following tooth extraction in the posterior maxilla, however, the role of this pneumatization in the overall changes in the vertical bone height is not clear.

    Purpose: To compare dimensional changes in the alveolar ridge and corresponding maxillary sinus following tooth extraction, with or without socket preservation.

    Materials And Methods: 42 patients underwent tooth extraction (control group) and 21 patients underwent tooth extraction with socket preservation using DBBM (study group). Read More

    Clinical, radiological, and gene expression analyses in smokers and non-smokers, Part 2: RCT on the late healing phase of osseointegration.
    Clin Implant Dent Relat Res 2017 Oct 26;19(5):901-915. Epub 2017 Jul 26.
    Department of Biomaterials, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Background: The mechanisms behind the impact of smoking on osseointegration are not fully understood.

    Purpose: To investigate the initial clinical and molecular course of osseointegration of different implants in smokers and non-smokers in a randomized controlled trial (RCT).

    Materials And Methods: Smoking (n = 16) and non-smoking (n = 16) patients received 3 implant types: machined, oxidized, and laser-modified surfaces. Read More

    Post-extraction implant placement into infected versus non-infected sites: A multicenter retrospective clinical study.
    Clin Implant Dent Relat Res 2017 Oct 26;19(5):833-840. Epub 2017 Jul 26.
    Section of Implant Dentistry and Oral Rehabilitation, Dental Clinic, IRCCS Galeazzi Institute, Milan, Italy.
    Purpose: The aim of this study was to assess whether immediate implant placement into post-extraction sites presenting a chronic infection poses a greater risk of implant failure than immediate placement in non-infected sites.

    Materials And Methods: Records of patients who underwent extraction and immediate implant placement into both infected and non-infected sites from January 1998 to September 2014 at 5 different dental centers were considered for inclusion. Included records were subjected to statistical analysis of survival rates, along with a number of other patient-, implant-, surgery-, and prosthesis-related variables. Read More

    Three-year clinical prospective follow-up of extrasinus zygomatic implants for the rehabilitation of the atrophic maxilla.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):926-934. Epub 2017 Jul 13.
    Department of Periodontology and Oral Implantology, Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Brazil.
    Background: Placement of extrasinus zygomatic implants to support implant-supported rehabilitation is still controversial due to the scarcity of data.

    Purpose: To evaluate the clinical outcomes of 94 extrasinus zygomatic implants, installed laterally to the maxillary sinus, for rehabilitation of the edentulous atrophic maxillae.

    Materials And Methods: A total of 42 patients (mean age 58 years) with severely atrophic maxillae were treated between November 2010 and July 2011, and followed up until July 2014. Read More

    Randomized clinical trial for the biological evaluation of two nanostructured biphasic calcium phosphate biomaterials as a bone substitute.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):802-811. Epub 2017 Jul 13.
    Dental Clinical Research Center, Oral Surgery Department, Dentistry School, Fluminense Federal University, Niteroi, Rio de Janeiro, Brazil.
    Background: The presence of nonresorbable residual granules of hydroxyapatite (HA) may decrease the bone/implant interface. To balance resorption and bone formation biphasic calcium phosphate ceramics compounds applied at different rates have been studied.

    Purpose: The aim of this trial was to compare the clinical, histological, and histomorphometric responses of two new biphasic calcium phosphate biomaterials in fresh dental sockets after 3 and 6 months. Read More

    A cost analysis of a long-term prospective study of patients treated with immediately loaded implant-supported mandibular overdentures.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):944-951. Epub 2017 Jul 13.
    Department of Oral Rehabilitation and Community Care, Faculty of Dental Surgery, University of Malta, Msida, Malta.
    Background: The economic burden for patients seeking treatment with implant-supported prostheses has not been given adequate attention.

    Purpose: To document long-term costs from a prospective trial on edentulous patients treated with mandibular implant-supported overdentures and 2 loading protocols.

    Materials And Methods: The direct clinical and time costs for 35 patients receiving an immediate-loading protocol (ILP) and 40 patients with a conventional-loading protocol, over 14 years of observation, were analyzed in 2016 Canadian dollars as a base year. Read More

    Stem cell therapy for reconstruction of alveolar cleft and trauma defects in adults: A randomized controlled, clinical trial.
    Clin Implant Dent Relat Res 2017 Oct 28;19(5):793-801. Epub 2017 Jun 28.
    Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan.
    Background: Stem cell therapy with bone marrow-derived mesenchymal stem cells is a promising tissue engineering strategy to promote regeneration of craniofacial bone.

    Purpose: To determine whether cell therapy with ex vivo expanded stem cell populations would be safe and efficacious in the regeneration of large alveolar defects in patients with a history of cleft palate or craniofacial trauma.

    Materials And Methods: Eighteen patients (10 patients with traumatic injury and 8 patients with cleft palate) presenting with missing teeth associated with horizontal alveolar bone deficiencies were included in this randomized controlled clinical trial. Read More

    Lateral ridge augmentation with two different ratios of deproteinized bovine bone and autogenous bone: A 2-year follow-up of a randomized and controlled trial.
    Clin Implant Dent Relat Res 2017 Oct 28;19(5):884-894. Epub 2017 Jun 28.
    Department of Oral & Maxillofacial Surgery, Aalborg University Hospital, Aalborg, Denmark.
    Background: The optimal ratio of deproteinized bovine bone (DPBB) and autogenous bone (AB) for lateral augmentation is presently unknown.

    Purpose: To evaluate implant treatment outcome and radiological graft changes after lateral ridge augmentation with 2 different mixtures of DPBB and AB, 2 years after functional loading.

    Materials And Methods: Thirteen patients were included in a split mouth, randomized, controlled trial. Read More

    Immediate loading of four interforaminal implants supporting a locator-retained mandibular overdenture in the elderly. Results of a 3-year randomized, controlled, prospective clinical study.
    Clin Implant Dent Relat Res 2017 Oct 27;19(5):895-900. Epub 2017 Jun 27.
    Department of Dental Medicine and Oral Health, Division of Oral Surgery and Orthodontics, Medical University of Graz, Austria.
    Background: Implant-retained overdentures have become a standard option for the prosthetic treatment of the edentulous mandible in the elderly.

    Purpose: This prospective study aimed to compare immediate and conventional loading of four interforaminal implants supporting a Locator-retained mandibular overdenture in elderly patients regarding implant survival, implant stability, and implant-related complications.

    Material And Methods: The study population comprised 20 completely edentulous patients (11 males) aged 60 years and older with severe mandible resorption. Read More

    Resonance frequency analysis of dental implants placed at the posterior maxilla varying the surface treatment only: A randomized clinical trial.
    Clin Implant Dent Relat Res 2017 Oct 20;19(5):770-775. Epub 2017 Jun 20.
    Department of Prosthodontics, School of Dentistry, University of São Paulo, São Paulo, Brazil.
    Background: Chemical modifications of the dental implant surface that improve the wettability result in a faster and better osseointegration.

    Purpose: The aim of this randomized clinical trial was to evaluate the implant stability quotient (ISQ) of implants with similar designs, treated with 2 surfaces, sandblasted acid-etched (SAE) and hydrophilic SAE, within the initial 16 weeks of healing.

    Material And Methods: A total of 64 implants (32 SAE-control group and 32 modified SAE-test group) with the same design, length, and diameter (conical and compressive, 4. Read More

    Incidental findings of implant complications on postimplantation CBCTs: A cross-sectional study.
    Clin Implant Dent Relat Res 2017 Oct 20;19(5):776-782. Epub 2017 Jun 20.
    Faculty of Medicine and Dentistry, University of Alberta, Canada.
    Background: Survival rates of dental implants are reported to be very high and seem to indicate minimal complications related to dental implants.

    Purpose: The aim of this report was to evaluate in a cross-sectional study the prevalence of implant positioning complications as appears in postimplantation Cone-Beam Computerized Tomography (CBCT) in two of the major imaging facilities in Bucharest, Romania.

    Methods: Demographic and implant data was collected from two of the three main CBCT facilities in Bucharest, Romania. Read More

    Biophysical regulation of osteotomy healing: An animal study.
    Clin Implant Dent Relat Res 2017 Aug 13;19(4):590-599. Epub 2017 Jun 13.
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford School of Medicine, Stanford, California, 94305.
    Background: Osteotomies have been performed for centuries yet there remains a remarkable lack of consensus on optimal methods for cutting bone. There is universal agreement, however, that preserving cell viability is critical.

    Purpose: To identify mechanobiological parameters influencing bone formation after osteotomy site preparation. Read More

    On stress/strain shielding and the material stiffness paradigm for dental implants.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):935-943. Epub 2017 Jun 13.
    Faculty of Mechanical Engineering, Technion, Haifa, 32000, Israel.
    Background: Stress shielding considerations suggest that the dental implant material's compliance should be matched to that of the host bone. However, this belief has not been confirmed from a general perspective, either clinically or numerically.

    Purpose: To characterize the influence of the implant stiffness on its functionality using the failure envelope concept that examines all possible combinations of mechanical load and application angle for selected stress, strain and displacement-based bone failure criteria. Read More

    CAD/CAM-fabricated ceramic implant-supported single crowns made from lithium disilicate: Final results of a 5-year prospective cohort study.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):876-883. Epub 2017 Jun 13.
    Department of Prosthetic Dentistry, Center for Dental Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
    Background: All-ceramic bilayer systems suffer from technique-sensitivity, resulting in increased technical complication rates. This might be overcome by monolithic reconstructions, facilitating digital workflows.

    Purpose: To evaluate the clinical and patient-reported outcome of CAD/CAM-fabricated implant-supported single crowns (ISCs) made of lithium disilicate (LS2 ) cemented on ceramic implants 5 years after implant installation. Read More

    Histomorphometric and immunohistochemical assessment of RUNX2 and VEGF of Biogran™ and autogenous bone graft in human maxillary sinus bone augmentation: A prospective and randomized study.
    Clin Implant Dent Relat Res 2017 Oct 13;19(5):867-875. Epub 2017 Jun 13.
    Universidade Estadual Paulista - UNESP, Surgery and Integrated Clinic Department, São Paulo, Brazil.
    Background: Few studies have been conducted to assess new bone formation using Biogran, a bioactive glass, in maxillary sinus bone augmentation through a prospective and randomized evaluation. Moreover, there are no studies that evaluate cellular behavior by immunohistochemical assessment for osteoblastic and vascular activity during bone repair.

    Purpose: The aim of this study is to compare new bone formation and cellular behavior with Biogran alone, a 1:1 combination of Biogran and autogenous bone graft, and autogenous bone graft alone in human maxillary sinuses. Read More

    A prospective randomized controlled trial of two-window versus solo-window technique by lateral sinus floor elevation in atrophic posterior maxilla: Results from a 1-year observational phase.
    Clin Implant Dent Relat Res 2017 Oct 5;19(5):783-792. Epub 2017 Jun 5.
    Fourth Division, Peking University School and Hospital of Stomatology, Beijing, China.
    Background: Implant failures are more common when multiple missing posterior teeth need lateral sinus floor elevation owing to inadequate tissue maturation after grafting. Effects of lateral window dimensions on vital bone formation have rarely been compared.

    Purpose: To compare endo-sinus bone formation between two- and solo-window techniques to rehabilitate multiple missing posterior teeth that need substantial augmentation. Read More

    Comparison between tapered and cylindrical implants in the posterior regions of the mandible: A prospective, randomized, split-mouth clinical trial focusing on implant stability changes during early healing.
    Clin Implant Dent Relat Res 2017 Aug 29;19(4):733-741. Epub 2017 May 29.
    Department of Restorative Dentistry, School of Dentistry, Federal University of Pelotas, Brazil.
    Background: Companies affirm that tapered implants show adequate initial stability, while their installation in the lower arch is uncommon in clinical practice.

    Purpose: To compare the clinical outcomes of tapered and cylindrical implants and to study their effect on bone site characteristics and peri-implant health during healing.

    Materials And Methods: The implant site dimensions were assessed by linear measurements using CBCT prior to the installation of 40 implants in the posterior mandible (20 tapered and 20 cylindrical). Read More

    Hybrid and fully-etched surface implants in periodontally healthy patients: A comparative retrospective study on marginal bone loss.
    Clin Implant Dent Relat Res 2017 Aug 29;19(4):663-670. Epub 2017 May 29.
    Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
    Background: Human studies on implants with the same design but with different surfaces are lacking at the present time.

    Purpose: The aim of this study was to compare the survival rate of and marginal bone loss (MBL) around 2 types of implants with the same design, but with different surfaces: fully "sandblasted and double-etched" (SDE) implants and hybrid (H) implants, with an apical SDE-surface and a coronal machined-surface.

    Materials And Methods: The SDE- and H-surfaces were previously analyzed under SEM and profilometer. Read More

    Effects of uncontrolled periodontitis on marginal bone alterations around implants: A case-control study.
    Clin Implant Dent Relat Res 2017 Aug 29;19(4):654-662. Epub 2017 May 29.
    Department of Oral Implants, School of Stomatology, State Key Laboratory of Military Stomatology, The Fourth Military Medical University, 145 West Changle Road, Xi'an, China.
    Background: The hypothesis of bacterial infection initiating marginal bone loss around dental implant in analogy with natural tooth is still in debate.

    Purpose: The aim of this retrospective study was to investigate the effects of uncontrolled periodontitis on marginal bone alterations around implants compared with the periodontal health group at a mean follow-up of at least 6 years.

    Materials And Methods: Thirty consecutive uncontrolled periodontally compromised patients (PCP) and 30 periodontally healthy patients (PHP), with a total of 96 Straumann implants (PCP = 55, PHP = 41) were matched for age, gender, smoking, and implant characteristics. Read More

    Neurophysiological changes associated with implant-associated augmentation procedures in the lower jaw.
    Clin Implant Dent Relat Res 2017 Aug 29;19(4):725-732. Epub 2017 May 29.
    Department of Oral Surgery, University Medical Centre of the Johannes Gutenberg University of Mainz, Mainz, Germany.
    Background: Neurophysiological changes after oral and maxillofacial surgery remain one of the topics of current research.

    Purpose: This study evaluated if implant placement associated with augmentation procedures increases the possibility of sensory disturbances or result in impaired quality of life during the healing period.

    Material And Methods: Patients who had obtained an implant placement in the lower jaw in combination with augmentation procedures were examined by implementing a comprehensive Quantitative Sensory Testing (QST) protocol for extra- and intraoral use. Read More

    Dimensional alterations following vertical ridge augmentation using collagen membrane and three types of bone grafting materials: A retrospective observational study.
    Clin Implant Dent Relat Res 2017 Aug 29;19(4):742-749. Epub 2017 May 29.
    Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, Republic of Korea.
    Background: Various biomaterials have been introduced for vertical ridge augmentation to replace autogenous block bone grafting.

    Purpose: This retrospective study radiographically evaluated dimensional alterations of the vertically augmented alveolar ridge using collagen membrane and 3 types of materials: autogenous bone block, allogenous bone block, and particulated bone substitute.

    Materials And Methods: The electronic medical records of 32 patients who received vertical ridge augmentation using 3 types of materials were searched: 9 for autogenous bone block, 12 for allogenous bone block, and 11 for particulated bone substitutes. Read More

    Location of implant-retained fixed dentures affects oral health-related quality of life.
    Clin Implant Dent Relat Res 2017 Aug 25;19(4):710-716. Epub 2017 May 25.
    Department of Prosthodontics, Showa University School of Dentistry, Tokyo, Japan.
    Background: The effects of the locations of dental implants on treatment outcomes, as evaluated by oral health-related quality of life (OHRQoL) assessment, remain controversial.

    Purpose: To investigate the association between the locations of dental implants and changes in OHRQoL.

    Materials And Methods: Sixty-eight subjects received implant treatment in the anterior or posterior region and completed the Oral Health Impact Profile (OHIP) questionnaire before and after treatment. Read More

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