617 results match your criteria Clinical EEG and Neuroscience [Journal]


The Longitudinal Effects of Electroconvulsive Therapy on Ictal Interhemispheric Coherence and Its Associations With Treatment Outcome: A Naturalistic Cohort Study.

Clin EEG Neurosci 2018 Jun 1:1550059418781698. Epub 2018 Jun 1.

1 Department of Psychiatry, Rijnstate Hospital, Arnhem, Netherlands.

Objectives: Electroconvulsive therapy (ECT) is an effective treatment for severe depression. Electroencephalogram (EEG) measures between ECT sessions seem to be related to the antidepressant efficacy of ECT. In this naturalistic cohort study, we examine longitudinal effects of ECT on interhemispheric EEG coherence measures during seizure activity and its relation to the antidepressant efficacy. Read More

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June 2018
1 Read

Multimodal Neuroimaging: Basic Concepts and Classification of Neuropsychiatric Diseases.

Clin EEG Neurosci 2018 Jun 1:1550059418782093. Epub 2018 Jun 1.

1 Uskudar University, Istanbul, Turkey.

Neuroimaging techniques are widely used in neuroscience to visualize neural activity, to improve our understanding of brain mechanisms, and to identify biomarkers-especially for psychiatric diseases; however, each neuroimaging technique has several limitations. These limitations led to the development of multimodal neuroimaging (MN), which combines data obtained from multiple neuroimaging techniques, such as electroencephalography, functional magnetic resonance imaging, and yields more detailed information about brain dynamics. There are several types of MN, including visual inspection, data integration, and data fusion. Read More

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Levodopa Reduces the Phase lag Index of Parkinson's Disease Patients: A Magnetoencephalographic Study.

Clin EEG Neurosci 2018 Jun 1:1550059418781693. Epub 2018 Jun 1.

1 Department of Functional Neurosurgery, Ruijin Hospital, Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.

Objectives: As a method of measuring the phase difference between 2 signals, the phase lag index (PLI) of the alpha and beta bands in patients with Parkinson's disease (PD) was investigated by using magnetoencephalography (MEG).

Methods: Eighteen PD patients were measured by MEG in the state of overnight withdrawal of levodopa and after levodopa treatment; meanwhile, Unified Parkinson's Disease Rating Scale (UPDRS) III scale was evaluated.

Results: Compared with healthy controls, alpha (8-13 Hz) PLI in the frontal and parietal areas elevated in PD patients, while the elevation was reversed by the levodopa treatment. Read More

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Latent Schizencephaly With Psychotic Phenotype or Schizophrenia With Schizencephaly? A Case Report and Review of the Literature.

Clin EEG Neurosci 2018 Jun 1:1550059418781119. Epub 2018 Jun 1.

1 National Institute of Mental Health, Klecany, Topolová 748, Czech Republic.

Objectives: Although schizencephaly belongs to the class of neurodevelopmental disorders, which are a well-known predisposing factor for psychosis, there is a lack of relevant studies and diagnostic guidelines on this relationship.

Method: A case report of first-episode psychosis with persistent negative symptoms associated with schizencephaly is described and compared with 7 other cases found in the literature.

Results: We found perinatal pathology, cognitive deficit, and EEG abnormality in a patient with atypical initial symptoms of psychosis such as olfactory hallucinations. Read More

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June 2018
2 Reads

Abnormal EEG Power Spectra in Acute Transient Global Amnesia: A Quantitative EEG Study.

Clin EEG Neurosci 2018 Jun 1:1550059418780780. Epub 2018 Jun 1.

2 Sleep Disorders Unit, Institute of Neurology, Catholic University, Rome, Italy.

Transient global amnesia (TGA) is a clinical syndrome characterized by retrograde and anterograde amnesia without other neurological deficits. Although electroencephalography (EEG) methods are commonly used in both clinical and research setting with TGA patients, few studies have investigated neurophysiological pattern in TGA using quantitative EEG (qEEG). The main aim of the present study was to extend these previous findings by exploring EEG power spectra differences between patients with acute TGA and healthy controls using the exact low-resolution brain electromagnetic tomography software (eLORETA). Read More

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June 2018
1 Read

EEG Differences in Two Clinically Similar Rapid Dementias: Voltage-Gated Potassium Channel Complex-Associated Autoimmune Encephalitis and Creutzfeldt-Jakob Disease.

Clin EEG Neurosci 2018 May 1:1550059418774686. Epub 2018 May 1.

3 Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.

Distinguishing treatable causes for rapidly progressive dementia from those that are incurable is vital. Creutzfeldt-Jakob disease (CJD) and voltage-gated potassium channel complex-associated autoimmune encephalitis (VGKC AE) are 2 such conditions with disparate outcomes and response to treatment. To determine the differences in electroencephalography between CJD and VGKC AE, we performed a retrospective review of medical records and examined clinical data, neuroimaging, and electroencephalographs performed in patients admitted for evaluation for rapidly progressive dementia diagnosed with CJD and VGKC AE at the Johns Hopkins Hospital and Bayview Medical Center between January 1, 2007 and December 31, 2015. Read More

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May 2018
14 Reads
3.16 Impact Factor

Diagnostic Performance of the Electroencephalogram in the Elderly Manifesting With Episodes of Unresponsiveness.

Clin EEG Neurosci 2018 May 1:1550059418776087. Epub 2018 May 1.

1 Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

This study aimed to determine diagnostic performance of the EEG in diagnosing seizures and to ascertain risk factors associated with seizures in the elderly presenting with episodes of unresponsiveness compared with younger patients. This is a cross-sectional study. Only EEGs requested with indication of transient unresponsiveness (TUR) were included. Read More

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May 2018
2 Reads

Elevated Serum Lipid Peroxidation and Reduced Vitamin C and Trace Element Concentrations Are Correlated With Epilepsy.

Clin EEG Neurosci 2018 May 1:1550059418772755. Epub 2018 May 1.

1 Department of Pharmacy, Noakhali Science and Technology University, Noakhali, Bangladesh.

Background: Epilepsy is one of the chronic and heterogeneous epidemic neurological disorders leading to substantial mortality. The aim of the present study was to investigate the serum levels of malondialdehyde (MDA), vitamin C, and trace elements namely zinc (Zn), copper (Cu), and manganese (Mn) in epileptic patients of Bangladesh and to establish if there are any pathophysiological correlations.

Methods: This was a case-control study with 40 generalized epileptic patients and 40 healthy subjects as controls. Read More

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Short-Term Impact of tDCS Over the Right Inferior Frontal Cortex on Impulsive Responses in a Go/No-go Task.

Clin EEG Neurosci 2018 May 1:1550059418777404. Epub 2018 May 1.

5 Aix-Marseille Universite', Centre National de la Recherche Scientifique, LNC Unite' Mixte de Recherche, Marseille, France.

Inhibitory control, a process deeply studied in laboratory settings, refers to the ability to inhibit an action once it has been initiated. A common way to process data in such tasks is to take the mean response time (RT) and error rate per participant. However, such an analysis ignores the strong dependency between spontaneous RT variations and error rate. Read More

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Electroencephalography Findings in Crohn's Disease.

Clin EEG Neurosci 2018 Apr 1:1550059418767589. Epub 2018 Apr 1.

1 University of Health Sciences, Umraniye, Istanbul, Turkey.

Objectives: Crohn's Disease (CD) is a chronic systemic inflammatory disease associated with various extraintestinal manifestations, including seizure as a neurological finding. In this study, the prevalence of seizure and electroencephalographic abnormalities in patients with CD was investigated.

Materials And Methods: This study involved 41 patients with CD (female/male: 25/16) and 39 subjects in the control group (female/male: 25/14). Read More

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Saliency of Vowel Features in Neural Responses of Cochlear Implant Users.

Clin EEG Neurosci 2018 Apr 1:1550059418770051. Epub 2018 Apr 1.

2 International Laboratory for Brain, Music & Sound Research, Montreal, Quebec, Canada.

Cochlear implants restore hearing in deaf individuals, but speech perception remains challenging. Poor discrimination of spectral components is thought to account for limitations of speech recognition in cochlear implant users. We investigated how combined variations of spectral components along two orthogonal dimensions can maximize neural discrimination between two vowels, as measured by mismatch negativity. Read More

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Diagnostic Performance and Utility of Quantitative EEG Analyses in Delirium: Confirmatory Results From a Large Retrospective Case-Control Study.

Clin EEG Neurosci 2018 Mar 1:1550059418767584. Epub 2018 Mar 1.

1 Vision and Motor System Research Group, Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Background: The lack of objective disease markers is a major cause of misdiagnosis and nonstandardized approaches in delirium. Recent studies conducted in well-selected patients and confined study environments suggest that quantitative electroencephalography (qEEG) can provide such markers. We hypothesize that qEEG helps remedy diagnostic uncertainty not only in well-defined study cohorts but also in a heterogeneous hospital population. Read More

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March 2018
3 Reads

Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population.

Clin EEG Neurosci 2018 Mar 1:1550059418767583. Epub 2018 Mar 1.

2 Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Richmond, VA, USA.

This study investigated the use of resting-state electroencephalography (EEG) data to help differentiate posttraumatic stress disorder (PTSD) symptom factors. The sample, 147 combat-exposed OIF/OEF (Operation Iraqi Freedom/Operation Enduring Freedom) Veterans and service members, was a polytrauma population with variable PTSD and mild traumatic brain injury (mTBI) diagnoses. Participants completed the PTSD Checklist (PCL) and resting-state EEG was assessed for 10 minutes, with eyes closed. Read More

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March 2018
1 Read

Neurofeedback-Based Enhancement of Single-Trial Auditory Evoked Potentials: Treatment of Auditory Verbal Hallucinations in Schizophrenia.

Clin EEG Neurosci 2018 Mar 1:1550059418765810. Epub 2018 Mar 1.

1 Translational Research Center, University Hospital of Psychiatry, University of Bern, Bern, Switzerland.

Auditory verbal hallucinations depend on a broad neurobiological network ranging from the auditory system to language as well as memory-related processes. As part of this, the auditory N100 event-related potential (ERP) component is attenuated in patients with schizophrenia, with stronger attenuation occurring during auditory verbal hallucinations. Changes in the N100 component assumingly reflect disturbed responsiveness of the auditory system toward external stimuli in schizophrenia. Read More

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March 2018
15 Reads

Auditory Mismatch Negativity and P300a Elicited by the "Optimal" Multi-feature Paradigm in Early Schizophrenia.

Clin EEG Neurosci 2018 Jul 4;49(4):238-247. Epub 2018 Mar 4.

2 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.

The mismatch negativity (MMN) is an EEG-derived event-related potential (ERP) elicited by any violation of a predicted auditory "rule," regardless of whether one is attending to the stimuli and is thought to reflect updating of the stimulus context. Redirection of attention toward a rare, distracting stimulus event, however, can be measured by the subsequent P3a component of the P300. Chronic schizophrenia patients exhibit robust MMN deficits, as well as reductions in P3a amplitude. Read More

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July 2018
1 Read

Using Mismatch Negativity to Investigate the Pathophysiology of Substance Use Disorders and Comorbid Psychosis.

Clin EEG Neurosci 2018 Jul 4;49(4):226-237. Epub 2018 Mar 4.

1 Temerty Centre for Therapeutic Brain Intervention, Division of Mood and Anxiety, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Substance use disorders (SUDs) have a devastating impact on society and place a heavy burden on health care systems. Given that alcohol, tobacco, and cannabis use have the highest prevalence, further understanding of the underlying pathophysiology of these SUDs is crucial. Electroencephalography is an inexpensive, temporally superior, and translatable technique which enables investigation of the pathobiology of SUDs through the evaluation of various event-related potential components, including mismatch negativity (MMN). Read More

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July 2018
3 Reads

Event-Related Potentials in the Clinical High-Risk (CHR) State for Psychosis: A Systematic Review.

Clin EEG Neurosci 2018 Jul 31;49(4):215-225. Epub 2018 Jan 31.

1 Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.

There is emerging evidence that identification and treatment of individuals in the prodromal or clinical high-risk (CHR) state for psychosis can reduce the probability that they will develop a psychotic disorder. Event-related brain potentials (ERPs) are a noninvasive neurophysiological technique that holds promise for improving our understanding of neurocognitive processes underlying the CHR state. We aimed to systematically review the current literature on cognitive ERP studies of the CHR population, in order to summarize and synthesize the results, and their implications for our understanding of the CHR state. Read More

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July 2018
4 Reads

Reevaluation of the Critically Ill Patients With Nonconvulsive Status Epilepticus by Using Salzburg Consensus Criteria.

Clin EEG Neurosci 2018 Jan 1:1550059417752437. Epub 2018 Jan 1.

5 Department of Neurology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

Objective: We aimed to assess the usefulness of the Salzburg Consensus Criteria (SCC) for determining the prognosis of critically ill patients with nonconvulsive status epilepticus (NCSE).

Methods: We retrospectively reviewed consecutive patients with unconsciousness followed up in the intensive care unit (ICU). Three clinical neurophysiologists, one of them blinded to clinical and laboratory data, reevaluated all EEG data independently and determined NCSE according to SCC. Read More

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January 2018
5 Reads

NREM Sleep and Antiepileptic Medications Modulate Epileptiform Activity by Altering Cortical Synchrony.

Clin EEG Neurosci 2017 Dec 1:1550059417747436. Epub 2017 Dec 1.

1 Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.

Introduction: The activating role of non-rapid eye movement (NREM) sleep on epileptic cortex and conversely, the seizure remission brought about by antiepileptic medications, has been attributed to their effects on neuronal synchrony. This study aims to understand the role of neural synchrony of NREM sleep in promoting interictal epileptiform discharges (IEDs) in patients with epilepsy (PWE) by assessing the peri-IED phase synchrony during awake and sleep states. It also studies the role played by antiepileptic drugs (AEDs) on EEG desynchronization in the above cohort. Read More

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December 2017
6 Reads

The Use of Quantitative EEG for Differentiating Frontotemporal Dementia From Late-Onset Bipolar Disorder.

Clin EEG Neurosci 2018 May 29;49(3):171-176. Epub 2017 Dec 29.

1 Department of Psychology, Uskudar University, Istanbul, Turkey.

The behavioral variant frontotemporal dementia (bvFTD) usually emerges with behavioral changes similar to changes in late-life bipolar disorder (BD) especially in the early stages. According to the literature, a substantial number of bvFTD cases have been misdiagnosed as BD. Since the literature lacks studies comparing differential diagnosis ability of electrophysiological and neuroimaging findings in BD and bvFTD, we aimed to show their classification power using an artificial neural network and genetic algorithm based approach. Read More

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May 2018
4 Reads

Clinical and Biochemical Outcomes Following EEG Neurofeedback Training in Traumatic Brain Injury in the Context of Spontaneous Recovery.

Clin EEG Neurosci 2017 Dec 1:1550059417744899. Epub 2017 Dec 1.

1 Department of Clinical Psychology, National Institute of Mental Health & Neuro Sciences, Bengaluru, Karnataka, India.

It has been found that reduction of posttraumatic stress symptoms is positively associated with the reduction of postconcussive symptoms. Cortisol is commonly used as a biomarker of stress. Understanding the role of posttraumatic stress and cortisol in symptom reduction has implication for neuropsychological rehabilitation particularly in the context of spontaneous recovery. Read More

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December 2017
8 Reads

Does Valproic Acid/Na Valproate Suppress Auditory Startle Reflex in Patients With Epilepsy?

Clin EEG Neurosci 2017 Dec 1:1550059417747155. Epub 2017 Dec 1.

1 Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey.

Background And Objective: Auditory startle response (ASR) was normal in juvenile myoclonic epilepsy whereas it was suppressed in progressive myoclonic epilepsy. However, both groups were using valproic acid/Na valproate (VPA) in different doses. Therefore, we aimed to analyze whether VPA has an impact on ASR in a cohort of epilepsy. Read More

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December 2017
4 Reads

Subacute Encephalopathy With Seizures in Alcoholics (SESA) Presenting as Focal Nonconvulsive Status Epilepticus.

Clin EEG Neurosci 2017 Dec 1:1550059417747435. Epub 2017 Dec 1.

3 Marqués de Valdecilla University Hospital, Santander, Cantabria, Spain.

Purpose: To acquaint readers with the underrecognized subacute encephalopathy with seizures in chronic alcoholics (SESA) that has more recently been associated with different types of status epilepticus.

Methods: Case reports and review of the literature on SESA and nonconvulsive status epilepticus (NCSE).

Results: Two cases: one with alternating bifrontoparietal NCSE, and one with focal, confusional NCSE, with imaging and EEG correlates. Read More

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December 2017
6 Reads

Use of Transcranial Direct Stimulation in the Treatment of Negative Symptoms of Schizophrenia.

Clin EEG Neurosci 2018 Jan;49(1):18-26

1 Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Children Hospital Bambino Gesù, Rome, Italy.

Schizophrenia is a debilitating disease that affects approximately 1% of the population. Negative symptoms are among the major determinants of the functional impairment and a significant proportion of patients with negative symptoms will continue to experience these symptoms despite antipsychotic medications. There are promising results in the application of brain stimulation, particularly transcranial direct current stimulation (tDCS), for the reduction of negative symptoms of schizophrenia. Read More

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January 2018
5 Reads

Impact of Reward and Loss Anticipation on Cognitive Control: An Event-Related Potential Study in Subjects With Schizophrenia and Healthy Controls.

Clin EEG Neurosci 2018 Jan;49(1):46-54

1 Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy.

Introduction: Deficits of cognitive functions and motivation are core aspects of schizophrenia. The interaction of these deficits might contribute to impair the ability to flexibly adjust behavior in accordance with one's intentions and goals. Many studies have focused on the anterior N2 as a correlate of cognitive control based on motivational value. Read More

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January 2018
6 Reads

Electrophysiological Markers of Motivation in Psychosis.

Clin EEG Neurosci 2018 Jan;49(1):8-11

1 Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, Japan.

Motivation is associated with electrophysiological markers, such as awake state delta oscillation and frontal alpha asymmetry, as well as event-related potentials, such as error-related negativity, feedback-related negativity, and prepulse inhibition. These indicators provide an objective measure of motivational deficits in psychiatric conditions, and response to treatment. Also, these modalities of brain activities are drawing attention as a target of neurofeedback training. Read More

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January 2018
6 Reads

Avolition-Apathy and White Matter Connectivity in Schizophrenia: Reduced Fractional Anisotropy Between Amygdala and Insular Cortex.

Clin EEG Neurosci 2018 Jan;49(1):55-65

1 Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy.

The avolition/apathy domain of negative symptoms includes motivation- and pleasure-related impairments. In people with schizophrenia, structural and functional abnormalities were reported in key regions within the motivational reward system, including ventral-tegmental area (VTA), striatum (especially at the level of the nucleus accumbens, NAcc), orbitofrontal cortex (OFC), as well as amygdala (Amy) and insular cortex (IC). However, the association of the reported abnormalities with avoliton-apathy is still controversial. Read More

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January 2018
6 Reads

Electrophysiological and Neuroimaging Research on Negative Symptoms: Future Challenges.

Clin EEG Neurosci 2018 01;49(1):3-5

3 Centre for Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, University of Copenhagen, Copenhagen, Denmark.

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January 2018
7 Reads

The Neural Correlates of Negative Symptoms in Schizophrenia: Examples From MRI Literature.

Clin EEG Neurosci 2018 Jan;49(1):12-17

4 Centre for Psychology, Kristianstad University, Kristianstad, Sweden.

Negative symptoms of schizophrenia have a negative impact on psychosocial functioning and disease outcome. It is therefore important to investigate the pathophysiology underlying negative symptoms as this may aid the development of better treatment. In the current article, examples from studies investigating neural correlates of negative symptoms in schizophrenia are given. Read More

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January 2018
5 Reads

Relationship Between Persistent Negative Symptoms and Findings of Neurocognition and Neuroimaging in Schizophrenia.

Clin EEG Neurosci 2018 Jan;49(1):27-35

1 Department of Psychiatry, Faculty of Medicine, Istanbul University, Çapa, Istanbul, Turkey.

Negative symptoms are defined as loss or reduction of otherwise present behaviors or functions in illness situation, and they have constituted an important aspect of schizophrenia. Although negative symptoms have usually been considered as a single entity, neurobiological investigations yielded discrepant results. To overcome challenges that derive from this discrepancy, researchers have proposed several approaches to structure negative symptoms into more homogenous constructs. Read More

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January 2018
5 Reads

Change in Quantitative EEG Theta Cordance as a Potential Predictor of Repetitive Transcranial Magnetic Stimulation Clinical Outcome in Major Depressive Disorder.

Clin EEG Neurosci 2017 Nov 1:1550059417746212. Epub 2017 Nov 1.

1 Laboratory of Brain, Behavior, and Pharmacology, TMS Clinical and Research Program, Neuromodulation Division, Semel Institute at UCLA, Los Angeles, CA, USA.

Repetitive transcranial magnetic stimulation (rTMS) has demonstrated efficacy in major depressive disorder (MDD), although clinical outcome is variable. Change in the resting-state quantitative electroencephalogram (qEEG), particularly in theta cordance early in the course of treatment, has been linked to antidepressant medication outcomes but has not been examined extensively in clinical rTMS. This study examined change in theta cordance over the first week of clinical rTMS and sought to identify a biomarker that would predict outcome at the end of 6 weeks of treatment. Read More

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November 2017
8 Reads

Automatic Seizure Detection Based on Morphological Features Using One-Dimensional Local Binary Pattern on Long-Term EEG.

Clin EEG Neurosci 2017 Dec 1:1550059417744890. Epub 2017 Dec 1.

5 College of Engineering, The Ohio State University, Columbus, OH, USA.

Epileptic neurological disorder of the brain is widely diagnosed using the electroencephalography (EEG) technique. EEG signals are nonstationary in nature and show abnormal neural activity during the ictal period. Seizures can be identified by analyzing and obtaining features of EEG signal that can detect these abnormal activities. Read More

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December 2017
3 Reads

Ictal Rhythmic Alpha Sinusoidal Waves in 3 Cases of Anti-NMDAR Encephalitis.

Clin EEG Neurosci 2017 Nov 1:1550059417745185. Epub 2017 Nov 1.

1 Department of Neurology, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

Previous studies have shown that extreme delta brush and high beta/delta power ratio on electroencephalogram are suggestive of anti- N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis. Here we report 3 anti-NMDAR encephalitis patients with ictal rhythmic alpha sinusoidal waves in temporal regions, which suggested electrographic seizures in anti-NMDAR encephalitis and indicated potential for seizure occurrence in the future. Rhythmic alpha sinusoidal waves may be an electrographic feature and helpful in distinguishing anti-NMDAR encephalitis. Read More

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November 2017
3 Reads

Quantitative EEG Parameters for Prediction of Outcome in Severe Traumatic Brain Injury: Development Study.

Clin EEG Neurosci 2018 Jul 27;49(4):248-257. Epub 2017 Nov 27.

3 University of Turku, Turku, Finland.

Monitoring of quantitative EEG (QEEG) parameters in the intensive care unit (ICU) can aid in the treatment of traumatic brain injury (TBI) patients by complementing visual EEG review done by an expert. We performed an explorative study investigating the prognostic value of 59 QEEG parameters in predicting the outcome of patients with severe TBI. Continuous EEG recordings were done on 28 patients with severe TBI in the ICU of Turku University Hospital. Read More

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July 2018
6 Reads

Heightened Background Cortical Synchrony in Patients With Epilepsy: EEG Phase Synchrony Analysis During Awake and Sleep Stages Using Novel Ensemble Measure.

Clin EEG Neurosci 2018 May 1;49(3):177-186. Epub 2017 Mar 1.

1 Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India.

Introduction: Excessive cortical synchrony within neural ensembles has been implicated as an important mechanism driving epileptiform activity. The current study measures and compares background electroencephalographic (EEG) phase synchronization in patients having various types of epilepsies and healthy controls during awake and sleep stages.

Methods: A total of 120 patients with epilepsy (PWE) subdivided into 3 groups (juvenile myoclonic epilepsy [JME], temporal lobe epilepsy [TLE], and extra-temporal lobe epilepsy [Ex-TLE]; n = 40 in each group) and 40 healthy controls were subjected to overnight polysomnography. Read More

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May 2018
8 Reads

Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease.

Clin EEG Neurosci 2017 Feb 1:1550059417696179. Epub 2017 Feb 1.

1 Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA.

Introduction: The key mechanisms that connect Parkinson's disease pathology with dementia are unclear. We tested the hypothesis that the quantitative spectral electroencephalographic measure, delta bandpower, correlates with Lewy type synucleinopathy on pathological examination in Parkinson's disease. As a corollary hypothesis, we analyzed whether there would be delta bandpower electroencephalographic differences between Parkinson's disease dementia cases with and without pathological criteria for Alzheimer's disease. Read More

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February 2017
3 Reads

How Long Should Routine EEG Be Recorded to Get Relevant Information?

Clin EEG Neurosci 2017 Mar 1:1550059417698549. Epub 2017 Mar 1.

1 Clinical Neurophysiology Unit, Neurology Department, University Grenoble Alpes Hospital, Grenoble, France.

Objective: The optimal duration of routine EEG (rEEG) has not been determined on a clinical basis. This study aims to determine the time required to obtain relevant information during rEEG with respect to the clinical request.

Method: All rEEGs performed over 3 months in unselected patients older than 14 years in an academic hospital were analyzed retrospectively. Read More

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March 2017
3 Reads

Delta Brush Pattern Is Not Unique to NMDAR Encephalitis: Evaluation of Two Independent Long-Term EEG Cohorts.

Clin EEG Neurosci 2018 Jul 16;49(4):278-284. Epub 2017 Feb 16.

5 Department of Neuroscience, Institute of Experimental Medical Research, Istanbul University, Istanbul, Turkey.

Purpose: Although its specificity has not previously been investigated in other cohorts, delta brush pattern (DBP) is increasingly reported in the EEGs of patients with anti- N-methyl-d-aspartate receptor (NMDAR) encephalitis.

Methods: We aimed to investigate the DBP in the EEGs of 2 cohorts; patients with change in consciousness for various causes monitored in the intensive care unit (ICU) (n = 106) and patients with mesial temporal lobe epilepsy (MTLE) with or without antineuronal antibodies (n = 76).

Results: These patients were investigated for the presence of DBP, defined as an EEG pattern characterized by delta activity at 1 to 3 Hz with superimposed bursts of rhythmic 12- to 30-Hz activity. Read More

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July 2018
11 Reads

Status Epilepticus and Multiple Sclerosis: A Case Presentation and Literature Review.

Clin EEG Neurosci 2017 Jan 1:1550059417693732. Epub 2017 Jan 1.

1 Department of Neurology and Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To search the literature for the frequency, pathogenesis, prognosis, and treatment of seizures and status epilepticus (SE) in patients with multiple sclerosis (MS).

Methods: We report 2 patients with MS who presented with SE and review the literature.

Results: Seizures and SE episodes worsened during MS relapses in the first patient. Read More

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January 2017
25 Reads

The Significance of Impulsive Error in Children With ADHD.

Clin EEG Neurosci 2017 Nov 1:1550059417742297. Epub 2017 Nov 1.

1 Institute of Allied Health Science, National Cheng Kung University, Taiwan.

A deficit of inhibition ability is a neuropsychological problem in children with attention deficit hyperactivity disorder (ADHD). We investigated whether in children who made impulsive error (IE), less error-related negativity (ERN) would correlate with poorer executive attention functions (EAFs). Ninety children (49 with ADHD and 41 without ADHD) were investigated by a 4-minute simple reaction time task and simultaneous electroencephalogram. Read More

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November 2017
4 Reads

Negative Symptoms and Reward Disturbances in Schizophrenia Before and After Antipsychotic Monotherapy.

Clin EEG Neurosci 2018 Jan 17;49(1):36-45. Epub 2017 Nov 17.

1 Center for Neuropsychiatric Schizophrenia Research (CNSR) & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS), Copenhagen University Hospital, Mental Health Centre Glostrup, Denmark.

Background: Negative symptoms (NS) are a central part of the symptomatology of schizophrenia, which is highly correlated to the functional outcome. Disturbances of the brain reward system are suggested to be central in the pathogenesis of NS by decreasing motivation and hedonic experiences. In this study, we compared reward-related brain activity in patients improving and not improving in NS after treatment with amisulpride. Read More

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January 2018
4 Reads

Exploration of the Pathophysiology of Chronic Pain Using Quantitative EEG Source Localization.

Clin EEG Neurosci 2018 Mar 6;49(2):103-113. Epub 2017 Nov 6.

5 Departments of Neurology and Radiology, NYU Medical Center, New York, NY, USA.

Chronic pain affects more than 35% of the US adult population representing a major public health imperative. Currently, there are no objective means for identifying the presence of pain, nor for quantifying pain severity. Through a better understanding of the pathophysiology of pain, objective indicators of pain might be forthcoming. Read More

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March 2018
3 Reads

The Difficulty in Finding Relationships Between ERPs and Clinical Symptoms of Schizophrenia.

Authors:
Judith M Ford

Clin EEG Neurosci 2018 Jan 2;49(1):6-7. Epub 2017 Nov 2.

1 San Francisco Veterans Administration Medical Center, San Francisco, CA, USA.

It has been surprisingly difficult to find associations between neural signatures of schizophrenia and the symptoms that define it. That is, many of the legacy components of the event-related potential (ERP)- P50, N100, P200, P300-are reduced in patients with schizophrenia, in first-degree relatives of patients with schizophrenia, in schizophrenia patients early in their illness, and even in people at clinical high risk for schizophrenia. Nevertheless, these ERP components tend to be relatively insensitive to symptoms. Read More

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January 2018
3 Reads

Evaluating Brain-Computer Interface Performance in an ALS Population: Checkerboard and Color Paradigms.

Clin EEG Neurosci 2018 Mar 27;49(2):114-121. Epub 2017 Oct 27.

1 Department of Psychology, East Tennessee State University, Johnson City TN, USA.

The objective of this study was to investigate the performance of 3 brain-computer interface (BCI) paradigms in an amyotrophic lateral sclerosis (ALS) population (n = 11). Using a repeated-measures design, participants completed 3 BCI conditions: row/column (RCW), checkerboard (CBW), and gray-to-color (CBC). Based on previous studies, it is hypothesized that the CBC and CBW conditions will result in higher accuracy, information transfer rate, waveform amplitude, and user preference over the RCW condition. Read More

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March 2018
3 Reads

Features of Simultaneous Scalp and Intracranial EEG That Predict Localization of Ictal Onset Zone.

Clin EEG Neurosci 2018 May 25;49(3):206-212. Epub 2017 Oct 25.

2 University of Pittsburgh Comprehensive Epilepsy Center (UPCEC), University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Objective: To assess the utility of simultaneous scalp EEG in patients with focal epilepsy undergoing intracranial EEG evaluation after a detailed presurgical testing, including an inpatient scalp video EEG evaluation.

Methods: Patients who underwent simultaneous scalp and intracranial EEG (SSIEEG) monitoring were classified into group 1 or 2 depending on whether the seizure onset zone was delineated or not. Seizures were analyzed using the following 3 EEG features at the onset of seizures latency, location, and pattern. Read More

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May 2018
6 Reads

The Success Rate of Neurology Residents in EEG Interpretation After Formal Training.

Clin EEG Neurosci 2018 Mar 10;49(2):136-140. Epub 2017 Oct 10.

2 Department of Biostatistics, Hacettepe University, Ankara, Turkey.

EEG is an important tool for neurologists in both diagnosis and classification of seizures. It is not uncommon in clinical practice to see patients who were erroneously diagnosed as epileptic. Most of the time incorrect interpretation of EEG contributes significantly to this problem. Read More

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March 2018
4 Reads

Neuronal Dysexcitability May Be a Biomarker of Migraine: A Visual Evoked Potential Study.

Clin EEG Neurosci 2017 Sep 1:1550059417734106. Epub 2017 Sep 1.

1 Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

We report neuronal sensitization and impaired habituation in migraine using pattern reversal visual evoked potential (PRVEP) and correlate these with clinical characteristics of migraine. Sixty-five migraineurs and 30 healthy controls were included. A detailed clinical examination was done and migraine characteristics, including migraine trigger, photophobia, phonophobia, and allodynia were noted. Read More

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September 2017
4 Reads

Peri-ictal Prone Position Is Associated With Independent Risk Factors For Sudden Unexpected Death In Epilepsy: A Controlled Video-EEG Monitoring Unit Study.

Clin EEG Neurosci 2018 May 28;49(3):197-205. Epub 2017 Sep 28.

1 Departments of Neurology and Clinical Neurophysiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.

Introduction: Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in patients with chronic drug-resistant epilepsy, and peri-ictal prone position has been elucidated as a risk factor for SUDEP. We aimed to investigate consecutive patients in peri-ictal prone positions in our video EEG monitoring (VEM) unit and compare patients with and without peri-ictal prone position to emphasize its relationship with other independent risk factors for SUDEP.

Methods: We retrospectively screened all patients with peri-ictal prone position who underwent VEM for a 10-year period and these patients constituted the prone (+) group. Read More

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May 2018
5 Reads

Neural Processing of Musical and Vocal Emotions Through Cochlear Implants Simulation.

Clin EEG Neurosci 2018 May 28;49(3):143-151. Epub 2017 Sep 28.

1 International Laboratory for Brain Music and Sound Research, Center for Research on Brain, Language and Music, Department of Psychology, University of Montreal, Montreal, Quebec, Canada.

Cochlear implants (CIs) partially restore the sense of hearing in the deaf. However, the ability to recognize emotions in speech and music is reduced due to the implant's electrical signal limitations and the patient's altered neural pathways. Electrophysiological correlations of these limitations are not yet well established. Read More

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May 2018
5 Reads