Search our Database of Scientific Publications and Authors

I’m looking for a

    3824 results match your criteria Cleveland Clinic Journal of Medicine[Journal]

    1 OF 77

    Hydroxychloroquine: An old drug with new relevance.
    Cleve Clin J Med 2018 Jun;85(6):459-467
    Chief, Department of Rheumatology, Walter Reed National Military Medical Center, Bethesda, MD, USA.
    Hydroxychloroquine is an immunomodulatory drug that has been used for 60 years to treat malaria and autoimmune diseases such as systemic lupus erythematosus and inflammatory arthritis, and potential new uses and benefits continue to emerge. Toxicity concerns have been addressed with updated prescribing recommendations. Read More

    Thoracic aortic aneurysm: How to counsel, when to refer.
    Cleve Clin J Med 2018 Jun;85(6):481-492
    Director, Marfan and Other Connective Tissue Disorders Clinic, Aorta Center, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
    Thoracic aortic aneurysm (TAA) is usually clinically silent and progresses slowly until a tipping point is reached, after which the aortic diameter can expand more rapidly and the condition can potentially end in aortic dissection or rupture. Causes include bicuspid aortic valve and genetic syndromes (Marfan, Loeys-Dietz, and Ehlers-Danlos syndromes) and familial associations, but many cases are idiopathic. Clinicians should therefore be alert for clues on chest imaging, and consider screening in first-degree relatives of patients known to have aortic disease. Read More

    Evaluating suspected pulmonary hypertension: A structured approach.
    Cleve Clin J Med 2018 Jun;85(6):468-480
    Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH, USA.
    Pulmonary arterial hypertension (PAH) is a common consideration when patients have unexplained signs of cardiopulmonary disease. Guidelines have been issued regarding diagnosis and management of this condition. Since multiple conditions can mimic components of PAH, the clinician should think about the patient's total clinical condition before diagnosing and categorizing it. Read More

    What you can do for your fibromyalgia patient.
    Cleve Clin J Med 2018 May;85(5):367-376
    Staff, Department of Rheumatologic and Immunologic Disease, and Director, Fibromyalgia Clinic, Orthopaedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, USA.
    Patients with fibromyalgia typically have pain "all over," tender points, generalized weakness and fatigue, nonrestorative sleep, and a plethora of other symptoms. In contrast to inflammatory and autoimmune conditions, laboratory tests and physical examination findings are usually normal. American College of Rheumatology guidelines facilitate diagnosis. Read More

    Hypertrophic cardiomyopathy: A complex disease.
    Cleve Clin J Med 2018 May;85(5):399-411
    Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Heart and Vascular Institute, and Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, USA.
    Hypertrophic cardiomyopathy (HCM) is a complex cardiovascular disease with wide phenotypic variations. Despite significant advances in imaging and genetic testing, more information is needed about the roles and implications of these resources in clinical practice. Patients with suspected or established HCM should be evaluated at an expert referral center to allow for the best multidisciplinary care. Read More

    Genitourinary syndrome of menopause: Common problem, effective treatments.
    Cleve Clin J Med 2018 May;85(5):390-398
    Professor of Obstetrics and Gynecology and Professor of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
    After menopause, about half of all women experience genital, sexual, and urinary symptoms associated with decreases in estrogen, termed genitourinary syndrome of menopause. First-line therapies are nonhormonal vaginal lubricants and moisturizers. For persistent symptoms, prescription estrogen in cream and ring formulations is effective. Read More

    Idiopathic pulmonary fibrosis: What primary care physicians need to know.
    Cleve Clin J Med 2018 May;85(5):377-386
    Associate Professor of Medicine, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA.
    Idiopathic pulmonary fibrosis (IPF) is a specific type of fibrosing interstitial pneumonia of unknown cause. It is usually chronic and progressive, tends to affect mainly adults over age 60, has a predilection for men, and is often fatal. The condition is still underappreciated by pulmonologists and primary care physicians. Read More

    Correction: Physical examination in dyspnea.
    Cleve Clin J Med 2018 Apr;85(4):332
    Department of Internal Medicine, St. Joseph Mercy Ann Arbor Hospital, Ann Arbor, MI, USA.
    On page 949 of the article, "Diagnostic value of the physical examination in patients with dyspnea" (Shellenberger RA, Balakrishnan B, Avula S, Ebel A, Shaik S. Cleve Clin J Med 2017; 84[12]:943-950), the terms "abdominojugular reflex" and "hepatojugular reflex" should have been "abdominojugular reflux" and "hepatojugular reflux." This error also occurred in Table 5 on that page. Read More

    Gallstones: Watch and wait, or intervene?
    Cleve Clin J Med 2018 Apr;85(4):323-331
    Vice Chair, Department of Gastroenterology and Hepatology, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
    Gallstones are common in the United States, affecting an estimated 1 in 7 adults. Fortunately, they are asymptomatic in up to 80% of cases, and current guidelines do not recommend cholecystectomy unless they cause symptoms. Laparoscopic cholecystectomy is the standard treatment for symptomatic gallstones, acute cholecystitis, and gallstone pancreatitis. Read More

    The female athlete triad: It takes a team.
    Cleve Clin J Med 2018 Apr;85(4):313-320
    Division of Women's Health, Internal Medicine, Mayo Clinic, Scottsdale, AZ, USA.
    The female athlete triad is a syndrome consisting of low energy availability (ie, burning more calories than one is taking in), menstrual dysfunction, and low bone mineral density, although all 3 components need not be present. Many providers, physical therapists, and coaches are unaware of it and thus do not screen for it. Early intervention using a team approach is essential in patients with any component of the female athlete triad to prevent long-term adverse health effects. Read More

    Musculoskeletal ultrasonography basics.
    Cleve Clin J Med 2018 Apr;85(4):283-300
    Director of Musculoskeletal Ultarsound, Section of Musculoskeletal Imaging, Imaging institute, Cleveland Clinic, Cleveland, OH, USA.
    Utrasonography is emerging as a core method to evaluate musculoskeletal problems. It is best used for imaging superficial structures limited to 1 quadrant of a joint. It has several advantages over other imaging methods: lower cost, ability to perform dynamic examinations, higher spatial resolution of superficial structures, better patient comfort, and essentially no contraindications. Read More

    Correction: Update on VTE.
    Cleve Clin J Med 2018 Mar;85(3):189
    Section Head, Department of Vascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
    In the article, "Update on the management of venous thromboembolism" (Bartholomew JR, Cleve Clin J Med 2017; 84[suppl 3]:39-46), 2 sentences in the text regarding dose reduction for body weight have errors. The corrected sentences follow: On page 42, left column, the last 5 lines should read: "The recommended dose should be reduced to 2.5 mg twice daily in patients that meet 2 of the following criteria: age 80 or older; body weight of 60 kg or less; or with a serum creatinine 1. Read More

    Acute cardiorenal syndrome: Mechanisms and clinical implications.
    Cleve Clin J Med 2018 Mar;85(3):231-239
    Director, Medical Critical Care Services, Borgess Medical Center, Kalamazoo MI, USA.
    Cardiac and renal dysfunction often coexist, and one begets the other. The association is referred to as cardiorenal syndrome. One subtype, acute cardiorenal syndrome, is often described as a clinical scenario in which acute worsening of cardiac function leads to acute kidney injury. Read More

    Which test for CAD should be used in patients with left bundle branch block?
    Cleve Clin J Med 2018 Mar;85(3):224-230
    Departments of Cardiovascular Medicine and Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, USA.
    Exercise stress electrocardiography is unreliable as a test for obstructive coronary artery disease (CAD) if the patient has left bundle branch block. The authors provide an algorithm for using alternative tests: exercise stress echocardiography, dobutamine echocardiography, computed tomographic (CT) angiography, and nuclear myocardial perfusion imaging. Read More

    Primary care management of chronic pelvic pain in women.
    Cleve Clin J Med 2018 Mar;85(3):215-223
    The Nebraska Medical Center, Omaha, NE, USA.
    Chronic pelvic pain in women can arise from many causes and often results in significant declines in function and quality of life. A systematic approach for evaluating patients and initiating a management plan are recommended in the primary care setting. Comprehensive management strategies may include medication, pelvic physical therapy, and behavioral interventions. Read More

    Alzheimer dementia: Starting, stopping drug therapy.
    Cleve Clin J Med 2018 Mar;85(3):209-214
    Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
    Alzheimer disease is the most common type of dementia. Two classes of cognition-enhancing drugs are approved to treat the symptoms, and both have provided modest benefit in clinical trials. Psychotropic drugs are sometimes used off-label to treat behavioral symptoms of Alzheimer disease. Read More

    1 OF 77