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    2689 results match your criteria Cleft Palate-Craniofacial Journal[Journal]

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    What We Do: The Hynes Pharyngoplasty-Deep Prevertebrae Stitch.
    Cleft Palate Craniofac J 2018 Jan 1:1055665617748723. Epub 2018 Jan 1.
    1 North Themes Cleft Lip and Palate Service. Great Ormond Street Hospital, London, UK.
    The Hynes pharyngoplasty is the second most often performed procedure for velopharyngeal insufficiency in the United Kingdom and Ireland. A crucial step of the procedure is reliable fixation of the flaps onto the posterior pharynx wall. We prefer to fix the flaps to the prevertebral fascia. Read More

    Identifying Psychosocial Risk Factors Among Families of Children With Craniofacial Conditions: Validation of the Psychosocial Assessment Tool-Craniofacial Version.
    Cleft Palate Craniofac J 2018 Jan 1:1055665617748010. Epub 2018 Jan 1.
    3 Cleft Lip and Palate Center and Center for Complex Craniofacial Disorders, Section of Plastic and Reconstructive Surgery, Nationwide Children's Hospital, Columbus, OH, USA.
    Objective: To evaluate the psychometric properties of the Psychosocial Assessment Tool-Craniofacial Version (PAT-CV), a screening instrument for psychosocial risk in families of children with craniofacial conditions, and to examine risk classification of patients in a craniofacial population.

    Design: Prospective, cross-sectional, single-center study.

    Setting: Interdisciplinary cleft lip and palate/craniofacial center at a US children's hospital. Read More

    Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
    Cleft Palate Craniofac J 2017 May;54(3):338-342
    Objective  To study the phenotype and overview the clinical management on Cleft Lip and/or Palate (CL/P) with Nevoid Basal Cell Carcinoma Syndrome (NBCCS) patients in Peking University School and Hospital of Stomatology. Design  Case series study. Main Outcome Measures  To describe the clinical phenotype of 12 CL/P with NBCCS patients who fulfilled the diagnostic criteria as well as to explore clinical management. Read More

    Peer Reviewer Recognition 2016.
    • Authors:
    Cleft Palate Craniofac J 2017 Mar;54(2):123-125
    Dear CPCJ Peer Reviewers, As we start 2017, it is again time to say thank you to all the 2016 peer reviewers. Published bimonthly with a global readership, CPCJ is the official organ of the American Cleft Palate-Craniofacial Association. For the six issues of Volume 53, 2016, 114 articles were published in 963 pages with 756 print pages and 207 online-only pages. Read More

    Comparison of Three Methods of Rating Nasolabial Appearance in Cleft Lip and Palate.
    Cleft Palate Craniofac J 2017 07 31;54(4):400-407. Epub 2017 Jan 31.
    Objective: To investigate which of three methods of rating nasolabial appearance-esthetic index, visual analogue scale (VAS), or numerical scale with reference photographs-is optimal.

    Design: Experimental study.

    Setting: Radboud University Medical Centre, The Netherlands and University of Bern, Switzerland. Read More

    Speech in Adults Treated for Unilateral Cleft Lip and Palate: Long-Term Follow-Up After One- or Two-Stage Palate Repair.
    Cleft Palate Craniofac J 2017 Nov 31;54(6):639-649. Epub 2017 Jan 31.
    Objective:   To evaluate speech in adults treated for unilateral cleft lip and palate with one-stage or two-stage palate closure and compare the speech of the patients with that of a noncleft control group.

    Design:   Cross-sectional study with long-term follow-up.

    Participants/setting:   All unilateral cleft lip and palate patients born from 1960 to 1987 and treated at Uppsala University Hospital, Sweden, were invited (n = 109). Read More

    Surgical Repositioning of the Premaxilla Using a Minimally Invasive Endonasal Approach.
    Cleft Palate Craniofac J 2017 01 31. Epub 2017 Jan 31.
    Objective: The aim of this study was to evaluate a technique for the surgical repositioning of the premaxilla using a minimally invasive endonasal approach.

    Design: Retrospective review of clinical records.

    Setting: Tertiary care, University Hospital, pediatric maxillofacial surgery unit. Read More

    A Family With Craniofrontonasal Syndrome: The First Report of Familial Cases of Craniofrontonasal Syndrome With Bilateral Cleft Lip and Palate.
    Cleft Palate Craniofac J 2017 Jan 31. Epub 2017 Jan 31.
    Craniofrontonasalsyndrome (CFNS) is a very rare genetic disorder, the common physical malformations of which include coronal synostosis, widely spaced eyes, clefting of the nasal tip, and various skeletal anomalies. Mutations of EFNB1, which encodes a member of the ephrin family of transmembrane ligands for Eph receptor tyrosine kinases, is the cause of CFNS. Although familial CFNS cases have been reported, no studies in the literature describe familial cases of CFNS expressing bilateral cleft lip and palate. Read More

    Incidence of Palatal Fistula at Time of Secondary Alveolar Cleft Reconstruction.
    Cleft Palate Craniofac J 2017 Jan 31. Epub 2017 Jan 31.
    Objective:   We aim to establish consistent time points for evaluating palatal fistula incidence to standardize reporting practices and clarify prospective literature.

    Design:   An institutional retrospective chart review was conducted on 76 patients with unilateral or bilateral complete cleft lip and palate who underwent secondary alveolar bone grafting between 2006 and 2015.

    Main Outcome Measures:   Early fistula incidence rates were reported prior to maxillary expansion, and late fistula rates were reported at the time of alveolar bone grafting. Read More

    Molecular Analysis of Ephrin A4 and Ephrin B1 in a Rabbit Model of Craniosynostosis: Likely Exclusion as the Loci of Origin.
    Cleft Palate Craniofac J 2017 Jan 30. Epub 2017 Jan 30.
    Craniosynostosis (CS) has a prevalence of approximately 1 in every 2000 live births and is characterized by the premature fusion of one or more cranial sutures. Failure to maintain the cell lineage boundary at the coronal suture is thought to be involved in the pathology of some forms of CS. The Ephrin family of receptor tyrosine kinases consists of membrane-bound receptors and ligands that control cell patterning and the formation of developmental boundaries. Read More

    Secondary Cleft Nasolabial Deformities: A New Classification System for Evaluation and Surgical Revision.
    Cleft Palate Craniofac J 2017 Jan 17. Epub 2017 Jan 17.
    Introduction:   Secondary or residual cleft lip and nasal deformities following primary unilateral or bilateral cleft lip repair are common. Many classification systems have been proposed to describe congenital cleft lip and palate deformities before repair. This article proposes a one-of-a-kind classification system for residual cleft deformities and describes its application to 136 cleft lip revision cases from cleft outreach missions worldwide. Read More

    Dental Arch Relationships and Reverse Headgear Effects in Southern Chinese Patients with Unilateral Cleft Lip and Palate: A Retrospective Study.
    Cleft Palate Craniofac J 2017 Jan 17. Epub 2017 Jan 17.
    Objective:   To evaluate the severity of the dental arch relationships and the treatment outcomes of reverse headgear (RHG) in southern Chinese patients with unilateral cleft lip and palate (UCLP).

    Design:   A retrospective study.

    Setting:   Faculty of Dentistry, The University of Hong Kong. Read More

    Effects of Bisphosphonate Administration on Cleft Bone Graft in a Rat Model.
    Cleft Palate Craniofac J 2017 Nov 17;54(6):687-698. Epub 2017 Jan 17.
    Objective:   Bone grafts in patients with cleft lip and palate can undergo a significant amount of resorption. The aim of this study was to investigate the effects of bisphosphonates (BPs) on the success of bone grafts in rats.

    Design:   Thirty-five female 15-week-old Fischer F344 Inbred rats were divided into the following experimental groups, each receiving bone grafts to repair an intraoral CSD: (1) Graft/saline: systemic administration of saline and (2) systemic administration of zoledronic acid immediately following surgery (graft/BP/T0), (3) 1 week postoperatively (graft/BP/T1), and (4) 3 weeks postoperatively (graft/BP/T2). Read More

    Comparing Modified Huddart-Bodenham Scoring System and GOSLON Yardstick to Assess Dental Arch Relationships in Unilateral Cleft Lip and Palate Patients.
    Cleft Palate Craniofac J 2017 Jan 16. Epub 2017 Jan 16.
    Objective:   To test the reliability of the modified Huddart-Bodenham (MHB) numerical scoring system and its agreement with the GOSLON Yardstick categorization for assessing the dental arch relationships in unilateral cleft lip and palate (UCLP) cases.

    Design:   A retrospective study.

    Setting:   Faculty of Dentistry, The University of Hong Kong. Read More

    Effect of Presurgical Nasoalveolar Molding on Nasal Symmetry in Unilateral Complete Cleft Lip/Palate Patients After Primary Cheiloplasty Without Concomitant Nasal Cartilage Dissection: Early Childhood Evaluation.
    Cleft Palate Craniofac J 2017 Jan 13. Epub 2017 Jan 13.
    Objective:   The objective of this study was to assess the efficacy of presurgical nasoalveolar molding (PNAM) on long-term nasal symmetry and shaping after primary cheiloplasty in patients with unilateral complete cleft lip/palate (UCL/P).

    Design:   This was a two-group, parallel, prospective, randomized clinical trial.

    Setting:   The setting for this study was the Chang Gung Craniofacial Center in Taoyuan, Taiwan. Read More

    A Sustainable Model for Patient Follow-Up Following an International Cleft Mission: A Proof of Concept.
    Cleft Palate Craniofac J 2017 Jan 13. Epub 2017 Jan 13.
    Purpose:   Patient follow-up after cleft missions is imperative if we are to critically assess the quality of care provided in these settings. The adoption of mobile telephones among disadvantaged families abroad may enable such an undertaking in a cost-effective manner. This project aimed to assess the efficacy of cellular phone-based follow-up in a developing country following a cleft mission to Thailand. Read More

    #Cleft: The Use of Social Media Amongst Parents of Infants with Clefts.
    Cleft Palate Craniofac J 2017 Jan 13. Epub 2017 Jan 13.
    Introduction:   Many societies and organizations are using social media to reach their target audience. The extent to which parents of patients with craniofacial anomalies use social media has yet to be determined. The goal of this study is to characterize and describe the use of social media by the parents of children with cleft lip and palate as it pertains to the care of their child. Read More

    TFII-I and AP2α Co-occupy the Promoters of Key Regulatory Genes Associated With Craniofacial Development.
    Cleft Palate Craniofac J 2017 Jan 13. Epub 2017 Jan 13.
    Objectives:   The aim of this study is to define the candidate target genes for TFII-I and AP2α regulation in neural crest progenitor cells.

    Design:   The GTF2I and GTF2IRD1 genes encoding the TFII-I family of transcription factors are prime candidates for the Williams-Beuren syndrome, a complex multisystem disorder characterized by craniofacial, skeletal, and neurocognitive deficiencies. AP2α, a product of the TFAP2A gene, is a master regulator of neural crest cell lineage. Read More

    Rotational Advancement in Cleft Nose Rhinoplasty - Buccal Mucosal Grafts Serve as a Powerful Tool.
    Cleft Palate Craniofac J 2017 Jan 10. Epub 2017 Jan 10.
    Objective:   Our aim was to analyze our technique of a modified rotational advancement in conjunction with buccal mucosal grafts (BMGs) in a subgroup of severe cleft cases.

    Design:   A retrospective clinical and photographic evaluation was conducted. Columella angle (CA) and tip projection (TPR) served as instruments in a photometric analysis. Read More

    Perceptual Judgments of Resonance, Nasal Airflow, Understandability, and Acceptability in Speakers With Cleft Palate: Ordinal Versus Visual Analogue Scaling.
    Cleft Palate Craniofac J 2017 Jan;54(1):19-31
    Objective:   To investigate the reliability of ordinal versus visual analogue scaling (VAS) ratings for perceptual judgments of nasal resonance, nasal airflow, understandability, and acceptability in speakers with cleft palate.

    Design:   Within-subjects comparative study.

    Setting:   Multisite. Read More

    Reliability of Oronasal Fistula Classification.
    Cleft Palate Craniofac J 2016 Dec 29. Epub 2016 Dec 29.
    Objective:   Oronasal fistula is an important complication of cleft palate repair that is frequently used to evaluate surgical quality, yet reliability of fistula classification has never been examined. The objective of this study was to determine the reliability of oronasal fistula classification both within individual surgeons and between multiple surgeons.

    Design:   Using intraoral photographs of children with repaired cleft palate, surgeons rated the location of palatal fistulae using the Pittsburgh Fistula Classification System. Read More

    Production of Two Nasal Sounds by Speakers With Cleft Palate.
    Cleft Palate Craniofac J 2016 Dec 29. Epub 2016 Dec 29.
    Manyspeakers with cleft palate develop atypical consonant productions, especially for pressure consonants such as plosives, fricatives, and affricates. The present study investigated the nature of nasal sound errors. The participants were eight female and three male speakers with cleft palate between the ages of 6 to 20. Read More

    Transforming Growth Factor Alpha Taq I Polymorphisms and Nonsyndromic Cleft Lip and/or Palate Risk: A Meta-Analysis.
    Cleft Palate Craniofac J 2016 Dec 21. Epub 2016 Dec 21.
    Background:   A series of epidemiological studies were conducted to investigate the association between transforming growth factor alpha (TGFA) polymorphism and nonsyndromic cleft lip and/or palate (CL/P) risk, but the findings remain conflicting. The present meta-analysis summarizes the association between the TGFA Taq I polymorphisms and nonsyndromic CL/P risk.

    Methods:   We searched PubMed, EMBASE, Web of Science, and Chinese Biomedical Literature databases from their inception to May 1, 2015. Read More

    Palatal Fistula Risk after Primary Palatoplasty: A Retrospective Comparison of a Humanitarian Organization and Tertiary Hospitals.
    Cleft Palate Craniofac J 2016 Dec 21. Epub 2016 Dec 21.
    Background:   Humanitarian surgical organizations provide palatoplasties for patients without access to surgical care. Few organizations have evaluated the outcomes of these trips. This study evaluates the palatal fistula rate in patients from two cohorts in rural China and one in the United States. Read More

    Content Validity of Patient-Reported Outcome Instruments Used With Pediatric Patients With Facial Differences: A Systematic Review.
    Cleft Palate Craniofac J 2016 Dec 21. Epub 2016 Dec 21.
    Objective:   The aim of this systematic review was to identify patient-reported outcome (PRO) instruments used in research with children/youth with conditions associated with facial differences to identify the health concepts measured.

    Design:   MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from 2004 to 2016 to identify PRO instruments used in acne vulgaris, birthmarks, burns, ear anomalies, facial asymmetries, and facial paralysis patients. We performed a content analysis whereby the items were coded to identify concepts and categorized as positive or negative content or phrasing. Read More

    Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe-EUROCRAN Study.
    Cleft Palate Craniofac J 2017 Nov 20;54(6):623-630. Epub 2016 Dec 20.
    Background:   Nonsyndromic cleft lip with or without cleft palate (nsCL±P) and nonsyndromic cleft palate (nsCP) are caused by a combination of genetic and environmental risk factors. We investigated gene-environment and gene-gene joint effects in a large multicenter study of case-parent triads.

    Methods:   The nsCL±P or nsCP triads were recruited in 11 European countries between 2001 and 2005. Read More

    The Cleft Aesthetic Rating Scale for 18-Year-Old Unilateral Cleft Lip and Palate Patients: A Tool for Nasolabial Aesthetics Assessment.
    Cleft Palate Craniofac J 2016 Dec 20. Epub 2016 Dec 20.
    Objective:   To develop a reliable and easy-to-use method to assess the nasolabial appearance of 18-year-old patients with unilateral cleft lip and palate (CLP).

    Design:   Retrospective analysis of nasolabial aesthetics using a 5-point ordinal scale and newly developed photographic reference scale: the Cleft Aesthetic Rating Scale (CARS). Three cleft surgeons and 20 medical students scored the nasolabial appearance on standardized frontal photographs. Read More

    The "Double" Tessier 7 Cleft: An Unusual Presentation of a Transverse Facial Cleft.
    Cleft Palate Craniofac J 2016 Dec 13. Epub 2016 Dec 13.
    Congenital macrostomia, or Tessier number 7 cleft, is a rare craniofacial anomaly. We present a unique patient with bilateral macrostomia that consisted of a "double" transverse cleft on the left side and a single transverse cleft on the right side. A staged reconstructive approach was used to repair the "double" left-sided clefts. Read More

    An Intercenter Comparison of Dental Arch Relationships and Craniofacial Form Including a Center Using Nasoalveolar Molding.
    Cleft Palate Craniofac J 2016 Nov 1. Epub 2016 Nov 1.
    Objective:   To compare dental arch relationship and craniofacial morphology of patients with CUCLP in pre-adolescence from five cleft centers including a center using NAM.

    Design:   Retrospective cohort study.

    Setting:   Five cleft centers in North America. Read More

    Preoperative Cleft Lip Measurements and Maxillary Growth in Patients With Unilateral Cleft Lip and Palate.
    Cleft Palate Craniofac J 2016 11;53(6):e198-e207
    Objective: Maxillary growth in patients with cleft lip and palate is highly variable. The authors' aim was to investigate associations between preoperative cleft lip measurements and maxillary growth determined cephalometrically in patients with complete unilateral cleft lip and palate (cUCLP).

    Design: Retrospective cross-sectional study. Read More

    Do Pharyngeal Flaps Restrict Early Midface Growth in Patients With Clefts?
    Cleft Palate Craniofac J 2016 Nov 11;53(6):629-633. Epub 2016 Jan 11.
    Objective:   To compare facial growth characteristics in patients with cleft palate who have undergone pharyngeal flap with those who had palatal lengthening or pharyngoplasty and to control subjects who have not had surgery for velopharyngeal insufficiency (VPI).

    Design:   Matched retrospective cohort study.

    Setting:   Multidisciplinary cleft care center. Read More

    Measuring Symmetry in Children With Unrepaired Cleft Lip: Defining a Standard for the Three-Dimensional Midfacial Reference Plane.
    Cleft Palate Craniofac J 2016 Nov 11;53(6):695-704. Epub 2016 Jan 11.
    Objective:   Quantitative measures of facial form to evaluate treatment outcomes for cleft lip (CL) are currently limited. Computer-based analysis of three-dimensional (3D) images provides an opportunity for efficient and objective analysis. The purpose of this study was to define a computer-based standard of identifying the 3D midfacial reference plane of the face in children with unrepaired cleft lip for measurement of facial symmetry. Read More

    Measuring Symmetry in Children With Cleft Lip. Part 2: Quantification of Nasolabial Symmetry Before and After Cleft Lip Repair.
    Cleft Palate Craniofac J 2016 Nov 31;53(6):705-713. Epub 2015 Dec 31.
    Objective:   The first part of this study validated an automated computer-based method of identifying the three-dimensional midfacial plane in children with unrepaired cleft lip. The purpose of this second part is to develop computer-based methods to quantify symmetry and to determine the correlation of these measures to clinical expectations.

    Participants:   A total of 35 infants with unrepaired unilateral cleft lip and 14 infant controls. Read More

    Cleft Lip Standardized Patient Examinations: The Role in Plastic Surgery Resident Education.
    Cleft Palate Craniofac J 2016 Nov 31;53(6):634-639. Epub 2015 Dec 31.
    Background:   Our institution has incorporated the use of objective structured clinical examinations (OSCE) in our residency curriculum. The OSCE provides trainee education and evaluation while addressing the six Accreditation Council for Graduate Medical Education (ACGME) core competencies required within training programs. We report our program's experience with the first cleft OSCE ever conducted. Read More

    The Feasibility of Buccal Fat Pad Flap in Oral Reconstruction Based on Clinical Experience in a Governmental Hospital, Alexandria, Egypt.
    Cleft Palate Craniofac J 2016 Nov 25;53(6):657-663. Epub 2015 Nov 25.
    Objective:   The purpose of this study was to evaluate the pedicled buccal fat pad flap for its applicability in the reconstruction of surgically created oral defects. We highlighted the technique of flap harvesting, its different applications, and limitations.

    Design:   Prospective analysis of patients with intraoral defects repaired by the buccal fat pad flap. Read More

    Dental Anomalies in a Brazilian Cleft Population.
    Cleft Palate Craniofac J 2016 Nov 17;53(6):714-719. Epub 2015 Nov 17.
    Objective:   The aim of this study was to radiographically investigate the prevalence of dental anomalies outside the cleft area in a group of Brazilian patients with nonsyndromic cleft lip and/or palate (NSCL/P).

    Design, Participants, And Setting:   A retrospective analysis of 207 panoramic radiographs of patients with NSCL/P aged 12 to 45 years without history of tooth extraction and orthodontic treatment was performed.

    Results:   Dental anomalies were found in 75. Read More

    Dose-Dependent Antiteratogenic Effects of Folic Acid on All-Trans Retinoic Acid-Induced Cleft Palate in Fetal Mice.
    Cleft Palate Craniofac J 2016 Nov 17;53(6):720-726. Epub 2015 Nov 17.
    Objective:   Although numerous studies have confirmed that consumption of folic acid (FA) during early pregnancy reduces the risk of oral facial clefts in newborn infants, the optimal dose of FA for reducing this risk remains unknown. We evaluated various doses of FA for their ability to reduce the incidence of all-trans retinoic acid (ATRA)-induced cleft palate in mice.

    Methods:   Pregnant C57BL/6J mice were randomly assigned to eight groups dosed with corn oil (control group), ATRA (80 mg/kg), FA (40 mg/kg), or ATRA (80 mg/kg) + FA (2. Read More

    Masticatory Rehabilitation of a Patient With Cleft Lip and Palate Malformation Using a Maxillary Full-Arch Reconstruction With a Prefabricated Fibula Flap.
    Cleft Palate Craniofac J 2016 Nov 17;53(6):736-740. Epub 2015 Nov 17.
    For full-arch reconstruction of an atrophied cleft maxilla with missing premaxilla, a prefabricated microvascular free bony flap is a relevant option. A fibula flap was prefabricated in a cleft patient who received six dental implants and an epithelial layer. Six weeks later, maxillary reconstruction was performed. Read More

    Early Detection of Cleft Lip by Three-Dimensional Transvaginal Ultrasound in Niche Mode in a Fetus With Trisomy 18 Diagnosed by Celocentesis.
    Cleft Palate Craniofac J 2016 Nov 27;53(6):745-748. Epub 2015 Oct 27.
    Transabdominal ultrasound examination carried out at 11.3 weeks' gestation suggested the diagnosis of holoprosencephaly (HPE). Transvaginal three-dimensional (3D) scan performed using the niche-mode technique enabled diagnosis of HPE, hypotelorism, and cleft lip (CL). Read More

    Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome: Expanding the Phenotype.
    Cleft Palate Craniofac J 2016 Nov 27;53(6):732-735. Epub 2015 Oct 27.
    We present a 3-month-old girl who displayed typical clinical characteristics of blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). She was referred to our clinic with an initial diagnosis of Down syndrome. Clinical features of elevated follicle stimulating hormone and low estradiol levels in the case were diagnosed as BPES syndrome and were consistent with BPES type 2. Read More

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