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J Foot Ankle Res 2021 Apr 13;14(1):30. Epub 2021 Apr 13.

Department of Physical Activity Sciences and Podiatric Medicine, Université du Québec à Trois-Rivières, 3351, boul. des Forges, C.P. 500, Trois-Rivières, G9A 5H7, Canada.

Background: An intractable plantar keratoma (IPK) is a conical thickening of the epidermis' stratum corneum and a common cause of foot pain which can have a significant, detrimental impact on the mobility, quality of life and independence of individuals. Conservative treatments are currently offered to patients with IPK, but they are unsatisfactory since they do not offer a sufficient or permanent reduction of symptoms. The purpose of this study was the evaluation of the feasibility, safety and effectiveness of innovative treatments for intractable plantar keratoma (IPK). Read More

J Peripher Nerv Syst 2021 Mar 2. Epub 2021 Mar 2.

Centre for Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.

Foot deformities are frequently observed in patients with Charcot Marie tooth disease (CMT) and orthopaedic surgery is often required. Currently there is no evidence-based guideline on surgical management and only a few studies which have evaluated long-term outcomes of surgical procedures. The aim of the study was to evaluate longitudinally the effect of foot surgery in a cohort of CMT patients. Read More

EFORT Open Rev 2021 Jan 4;6(1):15-23. Epub 2021 Jan 4.

Orthopedic Hospital Speising, Department of Pediatric Orthopaedics and Adult Foot and Ankle Surgery, Vienna, Austria.

Brachymetacarpia and brachymetatarsia are rare congenital presentations denoted by shortening of metacarpals and metatarsals respectively, in which the deformity usually presents around childhood/early adolescence.The aetiology is usually congenital besides several other syndromic or endocrinologic associations.Cosmetic issues such as absence of a normal-looking knuckle while making a fist or disruption of finger-tip curvature besides functional issues are the main indications for surgical intervention in brachymetacarpia. Read More

Geriatr Gerontol Int 2021 Feb 22;21(2):153-159. Epub 2020 Nov 22.

Department of Endocrinology, Hematology and Gerontology, Chiba University Graduate School of Medicine, Chiba, Japan.

Aim: To provide guidelines on the diagnosis, treatment, and prevention of skin ulcers in Werner syndrome.

Methods: This article was based on literature from 1996, when WRN was identified as a gene responsible for Werner syndrome, and we evaluated several authentic clinical cases of genetically diagnosed patients. There were 63 patients with Werner syndrome in the Japanese reports retrieved from Medical Online between January 1996 and December 2017. Read More

BMJ Case Rep 2020 Nov 2;13(11). Epub 2020 Nov 2.

Department of Orthopaedics, Atal Bihari Vajpayee Institute of Medical Sciences, Dr Ram Manohar Lohia Hospital, New Delhi, Delhi, India.

Orthop Surg 2020 Dec 19;12(6):1826-1834. Epub 2020 Oct 19.

Trauma Centre, Department of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Objective: To present a novel method called triplanar chevron osteotomy to treat hallux valgus (HV).

Methods: This is a retrospective study. In this study, the CT data of HV patients with painful callosities were evaluated retrospectively between 1 June 2018 and 1 June 2020. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Oct;34(10):1215-1220

Department of Orthopedics, the First Medical Center of Chinese PLA General Hospital, Beijing, 100853, P.R.China.

Objective: To investigate the effectiveness of rotationplasty in treating osteosarcoma of distal femur in children.

Methods: A clinical data of 10 children with osteosarcoma of distal femur treated with rotationplasty between March 2014 and June 2016 was retrospectively analyzed. There were 7 boys and 3 girls with an average age of 6. Read More

Int J Environ Res Public Health 2020 09 9;17(18). Epub 2020 Sep 9.

Israel Oceanography and Limnological Research, National Institute of Oceanography, Tel Shikmona, P.O. Box 8030, Haifa 31080, Israel.

Coral reef ecosystems are continuously degraded by anthropogenic and climate change drivers, causing a widespread decline in reef biodiversity and associated goods and services. In response, active restoration methodologies and practices have been developed globally to compensate for losses due to reef degradation. Yet, most activities employ the gardening concept that uses coral nurseries, and are centered in easily-accessible reefs, with existing infrastructure, and impractical for coral reefs in remote locations. Read More

J Morphol 2020 10 24;281(10):1328-1350. Epub 2020 Aug 24.

A.N. Severtsov Institute of Ecology and Evolution, Moscow, Russia.

The radula is the basic feeding structure in gastropod molluscs and exhibits great morphological diversity that reflects the exceptional anatomical and ecological diversity occurring in these animals. This uniquely molluscan structure is formed in the blind end of the radular sac by specialized cells (membranoblasts and odontoblasts). Secretion type, and the number and shape of the odontoblasts that form each tooth characterize the mode of radula formation. Read More

Toxins (Basel) 2020 08 7;12(8). Epub 2020 Aug 7.

The Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines.

The cone snails (family Conidae) are the best known and most intensively studied venomous marine gastropods. However, of the total biodiversity of venomous marine mollusks (superfamily Conoidea, >20,000 species), cone snails comprise a minor fraction. The venoms of the family Drilliidae, a highly diversified family in Conoidea, have not previously been investigated. Read More

J Am Podiatr Med Assoc 2020 May;110(3)

Background: We investigated the role of first metatarsal head shape in the etiology of hallux valgus. By pedobarographic analysis, we evaluated whether first metatarsal head shape causes an alteration in plantar pressure values that would result in metatarsalgia.

Methods: Referrals to our clinic for metatarsalgia, plantar fasciitis, and calcaneal spur were scanned retrospectively. Read More

Acta Orthop Traumatol Turc 2020 May;54(3):262-268

Department of Orthopaedics and Traumatology, Ortopediatri Academy of Pediatric Otrhopaedics, İstanbul, Turkey.

Objective: The aim of this study was to analyze the results of the split anterior tibialis tendon transfer (SPLATT) to peroneus tertius (PT) for equinovarus foot deformity in children with cerebral palsy (CP).

Methods: The medical records of 25 ambulatory CP patients (mean age: 8.7±3. Read More

Am Fam Physician 2020 05;101(10):623-624

Southern Colorado Family Medicine Residency, Pueblo, CO, USA.

Genome Biol Evol 2020 05;12(5):684-700

A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Science, Moscow, Russia.

Predatory gastropods of the superfamily Conoidea number over 12,000 living species. The evolutionary success of this lineage can be explained by the ability of conoideans to produce complex venoms for hunting, defense, and competitive interactions. Whereas venoms of cone snails (family Conidae) have become increasingly well studied, the venoms of most other conoidean lineages remain largely uncharacterized. Read More

Zootaxa 2020 Feb 20;4742(2):zootaxa.4742.2.8. Epub 2020 Feb 20.

Laboratório de Entomologia, Departamento de Zoologia, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Caixa Postal 68044, Rio de Janeiro, 21941-971, RJ, Brasil.

A new monotypic genus of Hoplojassini from French Guiana is proposed, described, and illustrated. Carinojassus gen. nov. Read More

Zootaxa 2020 Jan 7;4718(3):zootaxa.4718.3.9. Epub 2020 Jan 7.

Queensland Museum, South Brisbane, Queensland, Australia 4101..

New specimens and a re-examination of their holotypes have clarified the status of six nominal species of the extinct membracoid family Archijassidae from the Late Triassic (Norian) fossil insect localities at Mount Crosby, Denmark Hill and Dinmore in south-eastern Queensland. The 57 available tegmina ostensibly attributable to one or other of the six species are remarkably similar in venation and only vary in size and to a lesser extent in shape. The latter character varies subtlety across a continuum and is of no use in species definition. Read More

Diabetes Metab Syndr 2020 May - Jun;14(3):221-223. Epub 2020 Jan 3.

Fortis C-DOC Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology, India. Electronic address:

Many types of skin lesions have been described in patients with diabetes, but prolonged prayer-induced hyperkeratosis and callous formation are rare. We describe such lesions in a 62-year-old Muslim patient with uncontrolled glycemia who practiced prolonged, repeated religious prayers in sitting position causing significant pressure over dorsum of both ankles. He developed prayer-induced callous formation on dorsum of both ankles, with more thickening and a healed ulcer on left. Read More

Genes (Basel) 2020 02 21;11(2). Epub 2020 Feb 21.

Anti-Aging Research Institute of BIO-FD&C Co., Ltd., Incheon 21990, Korea.

Edelweiss () in the family is a wildflower that grows in rocky limestone places. Here, we investigated the efficacy of edelweiss callus culture extract ( callus culture extract; LACCE) using multiple assays from to as well as transcriptome profiling. Several assay results showed the strong antioxidant activity of LACCE in response to UVB treatment. Read More

J Am Acad Dermatol 2020 Nov 17;83(5):e327-e328. Epub 2020 Jan 17.

Department of Dermatology, Venereology, and Leprosy, Kalinga Institute of Medical Sciences, Bhubaneswar, India.

Dermatol Ther 2020 01 20;33(1):e13176. Epub 2019 Dec 20.

Department of Dermatology, University Hospital Basel, Basel, Switzerland.

Prayer marks are asymptomatic callosities resulting from repeated, extended pressure, and friction exerted on bony prominences when praying on hard ground. A 41-year-old woman with ulcerative colitis treated with infliximab was referred to our clinic due to skin changes on her feet that were suspected to be drug eruptions. The patient presented several asymptomatic, hyperpigmented, and hyperkeratotic plaques over the lateral malleoli suggesting that the lesions had a mechanical cause. Read More

J Dairy Sci 2020 Feb 20;103(2):1843-1855. Epub 2019 Nov 20.

Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animal Science, Sao Paulo State University (UNESP), Botucatu, SP, Brazil, 18618-681.

A systematic review was conducted to elucidate the role of teat-end hyperkeratosis (THK) as a risk factor for clinical mastitis (CM) or subclinical mastitis (SCM). Scientific papers on the subject were identified by means of a database search. All types of peer-reviewed analytical studies, observational or experimental and published in English, could be included in the review, regardless of publication year. Read More

Sci Rep 2019 11 22;9(1):17364. Epub 2019 Nov 22.

Department of Orthopaedics, The Third Hospital of Hebei Medical University, Shijiazhuang, P.R. China.

Hallux valgus (HV) is a foot deformity that can be treated with Chevron osteotomy, and a modified plantarward oblique osteotomy has been proposed in recent years. However, no research has focused on the correctional power of the osteotomy. The aim of this study was to examine the character of this plantarward oblique Chevron osteotomy (POCO) and to determine the rationale of this method. Read More

Zootaxa 2019 Apr 12;4585(2):zootaxa.4585.2.8. Epub 2019 Apr 12.

College of Life Science, Capital Normal University, 105 Xisanhuanbeilu, Haidian District, Beijing 100048, China.

A new genus and species of Cydnidae, Punctacorona triplosticha gen. et sp. nov. Read More

Zootaxa 2019 Mar 21;4568(3):zootaxa.4568.3.9. Epub 2019 Mar 21.

Departamento de Zoologia, Universidade Federal do Paraná. Caixa Postal 19020, 81531-980 Curitiba, PR, Brazil..

Two new monotypic genera of Gyponini from South America are proposed, described and illustrated. Caetana gen. nov. Read More

Nature 2019 07 26;571(7764):261-264. Epub 2019 Jun 26.

Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.

Until relatively recently, humans, similar to other animals, were habitually barefoot. Therefore, the soles of our feet were the only direct contact between the body and the ground when walking. There is indirect evidence that footwear such as sandals and moccasins were first invented within the past 40 thousand years, the oldest recovered footwear dates to eight thousand years ago and inexpensive shoes with cushioned heels were not developed until the Industrial Revolution. Read More

Br J Dermatol 2020 03 8;182(3):671-677. Epub 2019 Sep 8.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Background: Severely debilitating plantar keratoderma pain is the most distressing clinical feature of pachyonychia congenita (PC). Several earlier publications have reported therapeutic success with plantar injections of botulinum toxin (Btx).

Objectives: To describe our 4-year experience during which we administered a total of 30 plantar Btx injections to five patients with PC following an optimized protocol. Read More

Mod Rheumatol 2020 Mar 1;30(2):287-292. Epub 2019 Apr 1.

Department of Orthopedic Surgery, Tokyo Women's Medical University, Tokyo, Japan.

We aimed to investigate the relationship of callosities of the forefoot with foot deformity, the Health Assessment Questionnaire Disability Index (HAQ-DI) and modified total Sharp score (TSS) in patients with rheumatoid arthritis (RA). A total of 202 patients and 404 feet were enrolled. We examined the prevalence of callosities. Read More

J Foot Ankle Res 2019 14;12:13. Epub 2019 Feb 14.

1Behavioural and Health Sciences Department, Miguel Hernandez University, Ctra. Nnal. 332 s/n, 03550 San Juan de Alicante, Spain.

Background: Descriptions of the techniques for condylectomies via minimally invasive surgery (MIS) to treat interdigital helomas of the lesser toes are scarce in the literature. This study aimed to define and describe this surgical technique.

Methods: This observational study was performed using the Delphi method. Read More

J Am Podiatr Med Assoc 2018 Nov;108(6):466-471

Background:: An essential skill for podiatrists is conservative sharp debridement of foot callus. Poor technique can result in lacerations, infections and possible amputation. This pilot trial explored whether adding simulation training to a traditional podiatry clinical placement improved podiatry student skills and confidence in conservative sharp debridement, compared with traditional clinical placement alone. Read More