568 results match your criteria Classification and Complications of Traumatic Brain Injury


Complications and Mortality Among Correctly Triaged and Undertriaged Severely Injured Older Adults With Traumatic Brain Injuries.

Authors:
Linda J Scheetz

J Trauma Nurs 2018 Nov/Dec;25(6):341-347

Department of Nursing, Lehman College and The Graduate Center, CUNY, Bronx, New York.

Determining differences in clinical outcomes of older adults treated at trauma centers (TCs) and nontrauma centers (NTCs) is imperative considering their persistent undertriage and the projected costs of fixing the problem. This study compared the incidence and predictors of complications and mortality among brain-injured older adults treated at TCs and NTCs. This secondary analysis of New York inpatient data included patients aged 55+ years, primary brain injury diagnosis, and acute care hospital admission. Read More

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http://Insights.ovid.com/crossref?an=00043860-201811000-0000
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http://dx.doi.org/10.1097/JTN.0000000000000399DOI Listing
November 2018
9 Reads

Nationwide incidence and risk factors for posttraumatic seizures in children with traumatic brain injury.

J Neurosurg Pediatr 2018 Dec;22(6):684-693

2Department of Neurosurgery, University of Kansas Medical Center, Kansas City, Kansas.

OBJECTIVEPosttraumatic seizures (PTSs) are the most common complication following a traumatic brain injury (TBI) and may lead to posttraumatic epilepsy. PTS is well described in the adult literature but has not been studied extensively in children. Here, the authors utilized the largest nationwide registry of pediatric hospitalizations to report the national incidence, risk factors, and outcomes associated with PTS in pediatric TBI. Read More

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http://thejns.org/doi/10.3171/2018.6.PEDS1813
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http://dx.doi.org/10.3171/2018.6.PEDS1813DOI Listing
December 2018
8 Reads

Defining severe traumatic brain injury readmission rates and reasons in a rural state.

Trauma Surg Acute Care Open 2018 8;3(1):e000186. Epub 2018 Sep 8.

Department of Health Policy and Management, UAMS Medical Center, Little Rock, Arkansas, USA.

Background: Readmissions after a traumatic brain injury (TBI) have significant impact on long-term patient outcomes through interruption of rehabilitation. This study examined readmissions in a rural population, hypothesizing that readmitted patients after TBI will be older and have more comorbidities than those not readmitted.

Methods: Discharge data on all patients 15 years and older who were admitted to an Arkansas-based hospital for TBI were obtained from the Arkansas Hospital Discharge Data System from 2010 to 2014. Read More

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http://dx.doi.org/10.1136/tsaco-2018-000186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135415PMC
September 2018
1 Read

Direct oral anticoagulants do not worsen traumatic brain injury after low-level falls in the elderly.

Surgery 2018 10 8;164(4):814-819. Epub 2018 Aug 8.

Saint Joseph Mercy Ann Arbor, Department of Pharmacy, Ann Arbor, MI. Electronic address:

Background: Falls are now the leading cause of trauma and represent the most common type of trauma in the elderly. The use of anticoagulants is increasing in older patients, but there are little data on outcomes after traumatic brain injury while anticoagulated with direct oral anticoagulants compared with warfarin. We hypothesized that anticoagulated patients would have a greater mortality and complications than nonanticoagulated patients, and patients on direct oral anticoagulants would have more fatal outcomes after low-level falls because of lack of reversal agents. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00396060183032
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http://dx.doi.org/10.1016/j.surg.2018.05.060DOI Listing
October 2018
15 Reads

Imaging Post-Traumatic Headache.

Curr Pain Headache Rep 2018 Jul 30;22(10):64. Epub 2018 Jul 30.

Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.

Purpose Of Review: Headache is a frequent and debilitating symptom after mild traumatic brain injury, yet little is known about its pathophysiology and most effective treatments. The goal of this review is to summarize findings from imaging studies used during the clinical evaluation and research investigation of post-traumatic headache (PTH).

Recent Findings: There are no published recommendations or guidelines for when to acquire imaging studies of the head or neck in patients with PTH. Read More

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http://dx.doi.org/10.1007/s11916-018-0719-zDOI Listing
July 2018
9 Reads

Contribution of mental and physical disorders to disability in military personnel.

Occup Med (Lond) 2018 06;68(5):332-339

Research and Analysis Section, Directorate of Mental Health, Canadian Forces Health Services Group, Ottawa, Ontario, Canada.

Background: Combat operations in Southwest Asia have exposed millions of military personnel to risk of mental disorders and physical injuries, including traumatic brain injury (TBI). The contribution of specific disorders to disability is, however, uncertain.

Aims: To estimate the contributions of mental and physical health conditions to disability in military personnel. Read More

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http://dx.doi.org/10.1093/occmed/kqy066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012132PMC

Key Hospital Anxiety and Depression Scale (HADS) items associated with DSM-IV depressive and anxiety disorder 12-months post traumatic brain injury.

J Affect Disord 2018 08 21;236:164-171. Epub 2018 Apr 21.

Research and Development, Epworth HealthCare, Richmond, Victoria, Australia; Monash-Epworth Rehabilitation Research Centre, School of Psychological Sciences, Monash University, Clayton, Victoria, Australia.

Background: Anxiety and depression are common problems following traumatic brain injury (TBI), warranting routine screening. Self-report rating scales including the Hospital Anxiety and Depression Scale (HADS) are associated with depression and anxiety diagnoses in individuals with TBI. The relationship between individual HADS symptoms and structured clinical interview methods (SCID) requires further investigation, particularly in regard to identifying a small number of key items that can potentially be recognised by clinicians and carers of individuals with TBI. Read More

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http://dx.doi.org/10.1016/j.jad.2018.04.092DOI Listing
August 2018
2 Reads

Cushing's sign and severe traumatic brain injury in children after blunt trauma: a nationwide retrospective cohort study in Japan.

BMJ Open 2018 03 3;8(3):e020781. Epub 2018 Mar 3.

Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan.

Objective: We tested whether Cushing's sign could predict severe traumatic brain injury (TBI) requiring immediate neurosurgical intervention (BI-NSI) in children after blunt trauma.

Design: Retrospective cohort study using Japan Trauma Data Bank.

Setting: Emergency and critical care centres in secondary and tertiary hospitals in Japan. Read More

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http://dx.doi.org/10.1136/bmjopen-2017-020781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855168PMC
March 2018
5 Reads

What Determines Outcome in Patients That Suffer Raised Intracranial Pressure After Traumatic Brain Injury?

Acta Neurochir Suppl 2018 ;126:51-54

Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.

Introduction: Episodes of raised intracranial pressure (ICP) after traumatic brain injury (TBI) are responsible for the majority of secondary brain injury events and thereby strongly affect long-term outcome. However, not all patients with major episodes of raised ICP suffer a poor outcome. The aim of the current analysis was to identify variables contributing to good outcome in patients suffering episodes of high ICP. Read More

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http://dx.doi.org/10.1007/978-3-319-65798-1_11DOI Listing
July 2018
3 Reads

[Mild head injury].

Surg Neurol Int 2018 22;9(Suppl 1):S16-S28. Epub 2018 Jan 22.

Facultad de Medicina, Universidad Europea de Madrid, España, Spain.

Introduction: Mild traumatic brain injury (TBI) represents a major health concern, because a sizeable number of patients with mild TBI will develop potentially life-threatening complications. The target of this study was to describe a large series of adult patients suffering from mild TBI, treated at University Hospital of Getafe, between 2010 and 2015 ( = 2480). We examined the patients' epidemiological and baseline clinical profile, diagnosis, treatment and ultimate outcomes, to identify major prognostic factors that influence the final result. Read More

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http://dx.doi.org/10.4103/sni.sni_371_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799943PMC
January 2018
5 Reads

Outcomes of chronic subdural hematoma in patients with liver cirrhosis.

J Neurosurg 2018 Jan 1:1-10. Epub 2018 Jan 1.

5Anesthesiology and.

OBJECTIVEBurr hole craniostomy is an effective and simple procedure for treating chronic subdural hematoma (CSDH). However, the surgical outcomes and recurrence of CSDH in patients with liver cirrhosis (LC) remain unknown.METHODSA nationwide population-based cohort study was retrospectively conducted using data from the Taiwan National Health Insurance Research Database. Read More

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http://thejns.org/doi/10.3171/2017.8.JNS171103
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http://dx.doi.org/10.3171/2017.8.JNS171103DOI Listing
January 2018
7 Reads

Impact of grouping complications on mortality in traumatic brain injury: A nationwide population-based study.

PLoS One 2018 11;13(1):e0190683. Epub 2018 Jan 11.

Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan.

Traumatic brain injury (TBI) is an important health issue with high mortality. Various complications of physiological and cognitive impairment may result in disability or death after TBI. Grouping of these complications could be treated as integrated post-TBI syndromes. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190683PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764255PMC
February 2018
4 Reads

Motor-free composites from the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) for people with disabilities.

Rehabil Psychol 2017 Nov;62(4):464-473

Center for Health Assessment Research and Translation, University of Delaware.

Purpose/objective: The National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) includes a group of brief measures (i.e., 30 min) designed to assess language, processing speed, working memory, episodic memory, and executive functioning. Read More

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http://dx.doi.org/10.1037/rep0000185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283101PMC
November 2017
7 Reads

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

Epilepsia 2018 01 15;59(1):37-66. Epub 2017 Dec 15.

Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine, Hannover, Germany.

The most common forms of acquired epilepsies arise following acute brain insults such as traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for only 60%-70% of patients and remains symptomatic despite decades of effort to develop epilepsy prevention therapies. Recent preclinical efforts are focused on likely primary drivers of epileptogenesis, namely inflammation, neuron loss, plasticity, and circuit reorganization. Read More

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http://dx.doi.org/10.1111/epi.13965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993212PMC
January 2018
31 Reads

Interventions for managing skeletal muscle spasticity following traumatic brain injury.

Cochrane Database Syst Rev 2017 11 22;11:CD008929. Epub 2017 Nov 22.

Cochrane Australia, School of Public Health and Preventive Medicine, Monash University, L4 551 St Kilda Rd, Melbourne, Victoria, Australia, 3004.

Background: Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of pharmacological and non-pharmacological interventions, often used in combination. Management of spasticity following TBI varies from other clinical populations because of the added complexity of behavioural and cognitive issues associated with TBI. Read More

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http://doi.wiley.com/10.1002/14651858.CD008929.pub2
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http://dx.doi.org/10.1002/14651858.CD008929.pub2DOI Listing
November 2017
41 Reads

Efficacy of decompressive craniectomy in the management of intracranial pressure in severe traumatic brain injury.

J Neurosurg Sci 2017 Nov 7. Epub 2017 Nov 7.

Department of Neurological Surgery, University of California, San Francisco, CA, USA -

Traumatic brain injury (TBI) is a common cause of permanent disability for which clinical management remains suboptimal. Elevated intracranial pressure (ICP) is a common sequela following TBI leading to death and permanent disability if not properly managed. While clinicians often employ stepwise acute care algorithms to reduce ICP, a number of patients will fail medical management and may be considered for surgical decompression. Read More

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http://dx.doi.org/10.23736/S0390-5616.17.04133-9DOI Listing
November 2017
8 Reads

The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features.

J Alzheimers Dis 2018 ;61(1):17-28

Center for Neuropathology, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.

There is tremendous recent interest in chronic traumatic encephalopathy (CTE) in former collision sport athletes, civilians, and military veterans. This critical review places important recent research results into a historical context. In 2015, preliminary consensus criteria were developed for defining the neuropathology of CTE, which substantially narrowed the pathology previously reported to be characteristic. Read More

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http://dx.doi.org/10.3233/JAD-170654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734127PMC
July 2018
8 Reads

Update on critical care for acute spinal cord injury in the setting of polytrauma.

Neurosurg Focus 2017 Nov;43(5):E19

Department of Neurological Surgery, University of California, San Francisco.

Traumatic spinal cord injury (SCI) often occurs in patients with concurrent traumatic injuries in other body systems. These patients with polytrauma pose unique challenges to clinicians. The current review evaluates existing guidelines and updates the evidence for prehospital transport, immobilization, initial resuscitation, critical care, hemodynamic stability, diagnostic imaging, surgical techniques, and timing appropriate for the patient with SCI who has multisystem trauma. Read More

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http://dx.doi.org/10.3171/2017.7.FOCUS17396DOI Listing
November 2017
14 Reads

The outcome of patients in traumatic cardiac arrest presenting to deployed military medical treatment facilities: data from the UK Joint Theatre Trauma Registry.

J R Army Med Corps 2018 Jul 6;164(3):150-154. Epub 2017 Oct 6.

Academic Department of Military Emergency Medicine, Royal Centre for Defence Medicine (Research & Academia), Birmingham, UK.

Background: The UK military was continuously engaged in armed conflict in Iraq and Afghanistan between 2003 and 2014, resulting in 629 UK fatalities. Traumatic cardiac arrest (TCA) is a precursor to traumatic death, but data on military outcomes are limited. In order to better inform military treatment protocols, the aim of this study was to define the epidemiology of TCA in the military population with a particular focus on survival rates and injury patterns. Read More

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http://dx.doi.org/10.1136/jramc-2017-000818DOI Listing
July 2018
2 Reads

Raised intracranial pressure and brain edema.

Handb Clin Neurol 2017 ;145:25-37

Department of Pathology, Institute of Clinical Medicine, University of Eastern Finland and Department of Pathology, Kuopio University Hospital, Kuopio, Finland.

Acutely increased intracranial pressure (ICP) is a life-threatening neurosurgical emergency. Optimal management strategy is selected according to the causative process. Typical causes are intracranial bleeds like traumatic subdural, epidural, or intracerebral hematoma (ICH); spontaneous ICH, intraventricular hemorrhage, subarachnoid hemorrhage, and hydrocephalus. Read More

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http://dx.doi.org/10.1016/B978-0-12-802395-2.00004-3DOI Listing
January 2018
32 Reads

Dizziness-related disability following mild-moderate traumatic brain injury.

Brain Inj 2017 3;31(11):1436-1444. Epub 2017 Oct 3.

a Dept. of Physical Medicine and Rehabilitation , Oslo University Hospital HF , Oslo , Norway.

Objective: To investigate the associations between dizziness-related disability after mild- moderate Traumatic Brain Injury (TBI) and personal factors, injury-related factors and post-injury functioning using the International Classification of Functioning, Disability and Health (ICF) as a framework.

Methods: Baseline assessments for a Randomised Controlled Trial (RCT) were obtained for 65 patients (mean age 39.2 years; SD 12. Read More

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http://dx.doi.org/10.1080/02699052.2017.1377348DOI Listing
June 2018
16 Reads

Defining an Analytic Framework to Evaluate Quantitative MRI Markers of Traumatic Axonal Injury: Preliminary Results in a Mouse Closed Head Injury Model.

eNeuro 2017 Sep-Oct;4(5). Epub 2017 Sep 13.

Quantitative Medical Imaging Section, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD.

Diffuse axonal injury (DAI) is a hallmark of traumatic brain injury (TBI) pathology. Recently, the Closed Head Injury Model of Engineered Rotational Acceleration (CHIMERA) was developed to generate an experimental model of DAI in a mouse. The characterization of DAI using diffusion tensor magnetic resonance imaging (MRI; diffusion tensor imaging, DTI) may provide a useful set of outcome measures for preclinical and clinical studies. Read More

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http://dx.doi.org/10.1523/ENEURO.0164-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616192PMC
May 2018
11 Reads

Hypothermia for traumatic brain injury.

Cochrane Database Syst Rev 2017 09 21;9:CD001048. Epub 2017 Sep 21.

Patient Safety Research Department, Royal Lancaster Infirmary, Pointer Court 1, Ashton Road, Lancaster, UK, LA1 4RP.

Background: Hypothermia has been used in the treatment of brain injury for many years. Encouraging results from small trials and laboratory studies led to renewed interest in the area and some larger trials.

Objectives: To determine the effect of mild hypothermia for traumatic brain injury (TBI) on mortality, long-term functional outcomes and complications. Read More

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http://dx.doi.org/10.1002/14651858.CD001048.pub5DOI Listing
September 2017
4 Reads

Pneumatoceles in pediatric blunt trauma: Common and benign.

J Pediatr Surg 2018 Jul 7;53(7):1310-1312. Epub 2017 Aug 7.

Department of Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA.

Introduction: Traumatic pneumatoceles are reported to be rare in children and to have an uncertain clinical significance. We report a single institution series of traumatic pneumatoceles to better define their frequency and clinical significance.

Methods: After obtaining approval from the IRB, data were extracted from the trauma registry of a level 1 pediatric trauma center on children diagnosed with a pulmonary contusion (International Classification of Diseases-9th edition diagnosis codes: 861. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.08.002DOI Listing
July 2018
5 Reads

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift.

Neuron 2017 Sep;95(6):1246-1265

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and diversity in the pathogenesis and extent of injury contribute to differences in the course and outcome of TBI. Following the primary injury, extensive and lasting damage is sustained through a complex cascade of events referred to as "secondary injury. Read More

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http://dx.doi.org/10.1016/j.neuron.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678753PMC
September 2017
53 Reads
15 Citations
15.054 Impact Factor

Preliminary Validation of the World Health Organization Disability Assessment Schedule 2.0 for Mild Traumatic Brain Injury.

J Neurotrauma 2017 12 16;34(23):3256-3261. Epub 2017 Oct 16.

4 Division of Physical Medicine and Rehabilitation, University of British Columbia , Rehabilitation Research Program, GF Strong Rehab Centre, Rehabilitation Research Program, Vancouver, British Columbia, Canada .

The purpose of this study is to examine the reliability, factor structure, and validity of the World Health Organization Disability Assessment Schedule (WHODAS 2.0 12 item version) in a sample of patients who were slow to recover from a mild traumatic brain injury (mTBI). Participants were 79 adults with mTBI recruited from one of four specialty outpatient clinics in Vancouver, Canada. Read More

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http://www.liebertpub.com/doi/10.1089/neu.2017.5234
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http://dx.doi.org/10.1089/neu.2017.5234DOI Listing
December 2017
17 Reads

Risk Factors for Mild Traumatic Brain Injury and Subsequent Post-Traumatic Stress Disorder and Mental Health Disorders among United States Army Soldiers.

J Neurotrauma 2017 12 17;34(23):3249-3255. Epub 2017 Oct 17.

1 US Army Research Institute of Environmental Medicine , Military Performance Division, Natick, Massachusetts.

The purpose of this study was to determine the association of mild traumatic brain injury (mTBI) with subsequent post-traumatic stress disorder (PTSD) and mental health disorders (MHD), and the intervening role of acute stress disorder (ASD). This matched case-control study utilized the Total Army Injury and Health Outcomes Database (TAIHOD) to analyze soldiers' (n = 1,261,297) medical encounter data between 2002 and 2011. International Classification of Diseases, Ninth Revision (ICD-9) codes were used to identify: mTBI (following Centers for Disease Control [CDC] surveillance definition for mTBI), MHD (ICD-9 codes for depression and anxiety, excluding PTSD), PTSD (ICD-9 309. Read More

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http://dx.doi.org/10.1089/neu.2017.5101DOI Listing
December 2017
22 Reads

Traumatic brain injury, dry eye and comorbid pain diagnoses in US veterans.

Br J Ophthalmol 2018 05 26;102(5):667-673. Epub 2017 Aug 26.

Department of Ophthalmology, Miami VA Medical Center, Miami, Florida, USA.

Aims: The purpose of the study is to evaluate the relationship between dry eye (DE) and pain diagnoses in US veterans with and without traumatic brain injury (TBI).

Methods: Retrospective cohort study of veterans who were seen in the Veterans Administration Hospital (VA) between 1 January 2010 and 31 December 2014. Veterans were separated into two groups by the presence or absence of an International Classification of Diseases, Ninth Revision diagnosis of TBI and assessed for DE and other comorbidities. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2017-310509DOI Listing
May 2018
18 Reads

Top 10 Research Questions Related to Preventing Sudden Death in Sport and Physical Activity.

Res Q Exerc Sport 2017 Sep;88(3):251-268

a University of Connecticut.

Participation in organized sport and recreational activities presents an innate risk for serious morbidity and mortality. Although death during sport or physical activity has many causes, advancements in sports medicine and evidence-based standards of care have allowed clinicians to prevent, recognize, and treat potentially fatal injuries more effectively. With the continual progress of research and technology, current standards of care are evolving to enhance patient outcomes. Read More

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http://dx.doi.org/10.1080/02701367.2017.1342201DOI Listing
September 2017
10 Reads

TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice.

J Neuroimmunol 2017 09 20;310:38-45. Epub 2017 Jun 20.

Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong, University of Science and Technology, Wuhan, 430030, PR China. Electronic address:

Traumatic brain injury (TBI) initiates inflammatory responses that result in an enduring cascade of secondary neuronal loss and behavioural impairment. Toll-like receptor 4 (TLR4), predominantly expressed by microglia, recognizes damage-associated molecular patterns (DAMPs) and regulates inflammatory processes. Interestingly, the switch of microglial M1/M2 phenotypes after TBI is highly important regarding damage and restoration of neurological function. Read More

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http://dx.doi.org/10.1016/j.jneuroim.2017.06.006DOI Listing
September 2017
16 Reads

Work Productivity Loss After Mild Traumatic Brain Injury.

Arch Phys Med Rehabil 2018 02 29;99(2):250-256. Epub 2017 Jul 29.

Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA; Spaulding Rehabilitation Hospital, Boston, MA; Home Base, a Red Sox Foundation and Massachusetts General Hospital Program, Boston, MA.

Objectives: To examine the completeness of return to work (RTW) and the degree of productivity loss in individuals who do achieve a complete RTW after mild traumatic brain injury (MTBI).

Design: Multisite prospective cohort.

Setting: Outpatient concussion clinics. Read More

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http://dx.doi.org/10.1016/j.apmr.2017.07.006DOI Listing
February 2018
9 Reads

Psychometric properties and correlates of the PHQ-2 and PHQ-9 after traumatic brain injury.

Brain Inj 2017 7;31(13-14):1871-1875. Epub 2017 Jul 7.

b Calvin College , Grand Rapids , MI , USA.

Primary Objective: To determine the predictive accuracy of the Patient Health Questionnaire (PHQ)-2 in predicting PHQ-9 findings and to examine demographic, historical, and injury correlates of PHQ-9 ratings.

Research Design: Retrospective analysis of data collected as part of routine clinical outpatient care over a period of 30 months on 168 persons with mild to severe traumatic brain injury, who were referred for neuropsychological evaluation within 1-12 months after injury.

Main Outcomes And Results: PHQ-2 scores ≥2 had a sensitivity of 0. Read More

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http://dx.doi.org/10.1080/02699052.2017.1334962DOI Listing
July 2018
9 Reads

AAPT Diagnostic Criteria for Central Neuropathic Pain.

J Pain 2017 12 27;18(12):1417-1426. Epub 2017 Jun 27.

Danish Pain Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.

Central neuropathic pain, which is pain caused by a lesion or disease of the central somatosensory nervous system, is a serious consequence of spinal cord injury, stroke, multiple sclerosis, and other conditions affecting the central nervous system. A collaborative effort between the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks public-private partnership and the American Pain Society, the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks-American Pain Society Pain Taxonomy (AAPT) initiative, invited a working group to develop diagnostic criteria for central neuropathic pain. The criteria for central neuropathic pain that were developed expand upon existing criteria for neuropathic pain and the International Classification of Diseases 11th Revision draft criteria to ensure consistency. Read More

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http://dx.doi.org/10.1016/j.jpain.2017.06.003DOI Listing
December 2017
53 Reads
4.010 Impact Factor

Neurobehavioral Management of Traumatic Brain Injury in the Critical Care Setting: An Update.

Crit Care Clin 2017 Jul 20;33(3):423-440. Epub 2017 Apr 20.

Psychosomatic Medicine, Department of Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Palo Alto, CA 94305, USA. Electronic address:

Traumatic brain injury (TBI) is an alteration in brain function, or other evidence of brain pathology, caused by an external force. TBI is a major cause of disability and mortality worldwide. Post-traumatic amnesia, or the interval from injury until the patient is oriented and able to form and later recall new memories, is an important index of TBI severity and functional outcome. Read More

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http://dx.doi.org/10.1016/j.ccc.2017.03.011DOI Listing
July 2017
37 Reads

Anxiety and Posttraumatic Stress Disorder Among Medicare Beneficiaries After Traumatic Brain Injury.

J Head Trauma Rehabil 2017 May/Jun;32(3):178-184

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Drs Albrecht and Smith); Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Drs Peters and Rao); and Shock, Trauma and Anesthesiology Research-Organized Research Center, National Study Center for Trauma and Emergency Medical Services, University of Maryland, College Park (Dr Smith).

Objective: To estimate rates of anxiety and posttraumatic stress disorder (PTSD) diagnoses after traumatic brain injury (TBI) among Medicare beneficiaries, quantify the increase in rates relative to the pre-TBI period, and identify risk factors for diagnosis of anxiety and PTSD.

Participants: A total of 96 881 Medicare beneficiaries hospitalized with TBI between June 1, 2006 and May 31, 2010.

Design: Retrospective cohort study. Read More

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http://dx.doi.org/10.1097/HTR.0000000000000266DOI Listing
March 2018
11 Reads

Medical Symptom Validity Test Performance Following Moderate-Severe Traumatic Brain Injury: Expectations Based on Orientation Log Classification.

Arch Clin Neuropsychol 2017 May;32(3):339-348

Shepherd Center, GA , USA.

Objective: This study examined performance on the Medical Symptom Validity test (MSVT) during acute rehabilitation for moderate-severe traumatic brain injury (TBI) stratified by Orientation Log (O-Log) scores.

Method: Participants were 77 prospectively enrolled persons who sustained moderate-severe TBI and were acutely hospitalized secondary to the cognitive, medical and physical sequelae of their TBI. Participants were administered neuropsychological metrics, the O-Log and the MSVT a mean of 44 days post injury. Read More

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https://academic.oup.com/acn/article-lookup/doi/10.1093/arcl
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http://dx.doi.org/10.1093/arclin/acw112DOI Listing
May 2017
8 Reads

Sandbagging on the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) in a high school athlete population.

Arch Clin Neuropsychol 2017 May;32(3):259-266

Center for Brain, Biology and Behavior, University of Nebraska-Lincoln, Lincoln, NE,USA.

The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a computerized neuropsychological test battery commonly used to assess cognitive functioning after a concussion. It is recommended that application of ImPACT utilizes a baseline administration so athletes have an individualized baseline with which to compare post-injury results should they sustain a concussion. It has been suggested that athletes may provide suboptimal effort, called "sandbagging," in order to return to their baseline cognitive scores, and thus to play, more quickly. Read More

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https://academic.oup.com/acn/article-lookup/doi/10.1093/arcl
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http://dx.doi.org/10.1093/arclin/acw108DOI Listing
May 2017
2 Reads

Exploring predictors of treatment outcome in cognitive behavior therapy for sleep disturbance following acquired brain injury.

Disabil Rehabil 2018 08 19;40(16):1906-1913. Epub 2017 Apr 19.

a Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences , Monash University , Melbourne , Australia.

Purpose: To identify predictors of treatment response to cognitive behavior therapy (CBT) for sleep disturbance following acquired brain injury (ABI).

Methods: Classification and regression tree (CART) analysis was conducted on individual patient data from two pilot randomized controlled trials (RCTs): one in traumatic brain injury (TBI), the other in stroke. The combined sample comprised 32 participants; 15 receiving CBT and 17 allocated to treatment as usual (TAU). Read More

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http://dx.doi.org/10.1080/09638288.2017.1315461DOI Listing
August 2018
13 Reads

Detecting coached neuropsychological dysfunction: a simulation experiment regarding mild traumatic brain injury.

Clin Neuropsychol 2017 Nov 18;31(8):1412-1431. Epub 2017 Apr 18.

d Department of Psychology , VA Medical Center , Memphis , TN , USA.

Objective: Performance validity tests (PVTs) and symptom validity tests (SVTs) are often administered during neuropsychological evaluations. Examinees may be coached to avoid detection by measures of response validity. Relatively little research has evaluated whether graduated levels of coaching has differential effects upon PVT and SVT performance. Read More

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http://dx.doi.org/10.1080/13854046.2017.1318954DOI Listing
November 2017
3 Reads

The Development and Psychometric Evaluation of a Supplementary Index Score of the Neuropsychological Assessment Battery Screening Module that is Sensitive to Traumatic Brain Injury.

Arch Clin Neuropsychol 2017 Mar;32(2):215-227

Department of Occupational Therapy, University Hospitals Birmingham NHS Foundation Trust, UK.

Objective: This study examines the validity of the NAB Screening Module (screening module of the neuropsychological assessment battery, S-NAB) in an acute traumatic brain injury (TBI) inpatient population and provides psychometric evaluation of an original index sensitive to TBI impairment.

Method: The utility of the S-NAB as a TBI screen was examined using a between groups design. One-hundred and four patients with mild complicated to severe TBI were recruited from a consecutive cohort of patients admitted as inpatients to a UK Major Trauma Centre. Read More

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http://dx.doi.org/10.1093/arclin/acw087DOI Listing
March 2017
7 Reads

Early Brain Edema is a Predictor of In-Hospital Mortality in Traumatic Brain Injury.

J Emerg Med 2017 Jul 23;53(1):18-29. Epub 2017 Mar 23.

Department of Emergency Medicine, Wright State University, Boonshoft School of Medicine, Dayton, Ohio; Department of Neuroscience, Cell Biology and Physiology, Wright State University, Boonshoft School of Medicine, Dayton, Ohio.

Background: Identifying patients who may progress to a poor clinical outcome will encourage earlier appropriate therapeutic interventions. Brain edema may contribute to secondary injury in traumatic brain injury (TBI) and thus, may be a useful prognostic indicator.

Objective: We determined whether the presence of brain edema on the initial computed tomography (CT) scan of TBI patients would predict poor in-hospital outcome. Read More

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http://dx.doi.org/10.1016/j.jemermed.2017.02.010DOI Listing
July 2017
2 Reads

Inter-Subject Variability of Axonal Injury in Diffuse Traumatic Brain Injury.

J Neurotrauma 2017 07 3;34(14):2243-2253. Epub 2017 May 3.

2 Moss Rehabilitation Research Institute , Philadelphia, Pennsylvania.

Traumatic brain injury (TBI) is a leading cause of cognitive morbidity worldwide for which reliable biomarkers are needed. Diffusion tensor imaging (DTI) is a promising biomarker of traumatic axonal injury (TAI); however, existing studies have been limited by a primary reliance on group-level analytic methods not well suited to account for inter-subject variability. In this study, 42 adults with TBI of at least moderate severity were examined 3 months following injury and compared with 35 healthy controls. Read More

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http://dx.doi.org/10.1089/neu.2016.4817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510712PMC
July 2017
9 Reads

Increased prognostic accuracy of TBI when a brain electrical activity biomarker is added to loss of consciousness (LOC).

Am J Emerg Med 2017 Jul 20;35(7):949-952. Epub 2017 Feb 20.

BrainScope Co., Bethesda, MD, USA; New York University School of Medicine, Department of Psychiatry, New York, NY, USA. Electronic address:

Background: Extremely high accuracy for predicting CT+ traumatic brain injury (TBI) using a quantitative EEG (QEEG) based multivariate classification algorithm was demonstrated in an independent validation trial, in Emergency Department (ED) patients, using an easy to use handheld device. This study compares the predictive power using that algorithm (which includes LOC and amnesia), to the predictive power of LOC alone or LOC plus traumatic amnesia.

Participants: ED patients 18-85years presenting within 72h of closed head injury, with GSC 12-15, were study candidates. Read More

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http://dx.doi.org/10.1016/j.ajem.2017.01.060DOI Listing
July 2017
5 Reads

Factors associated with adverse outcomes in patients with traumatic intracranial hemorrhage and Glasgow Coma Scale of 15.

Am J Emerg Med 2017 Jun 25;35(6):875-880. Epub 2017 Jan 25.

Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, United States; Division of Neurocritical Care, University of Cincinnati, Cincinnati, OH, United States; Department of Neurosurgery, University of Cincinnati, Cincinnati, OH, United States. Electronic address:

Patients with mild traumatic brain injury (mTBI) with associated intracranial injury, or complicated mTBI, are at risk of deterioration. Clinical management differs within and between institutions. We conducted an exploratory analysis to determine which of these patients are unlikely to have an adverse outcome and may be future targets for less resource intensive care. Read More

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http://dx.doi.org/10.1016/j.ajem.2017.01.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482767PMC
June 2017
16 Reads

[Trends in computed tomography characteristics, intracranial pressure monitoring and surgical management in severe traumatic brain injury: Analysis of a data base of the past 25 years in a neurosurgery department].

Neurocirugia (Astur) 2017 Jan - Feb;28(1):1-14. Epub 2016 Dec 19.

Servicio de Neurocirugía, Hospital Universitario 12 de Octubre, Universidad Complutense (UCM), Madrid, España.

Objective: To describe the radiological characteristics, surgical indications, procedures, and intracranial pressure monitoring of a representative cohort of severe traumatic brain injury (sTBI) cases collected over the past 25years, and to analyse the changes that have occurred by dividing the period into 3 equal time periods.

Methods: An observational cohort study was conducted on consecutive adult patients (>14years of age) with severe closed TBI (Glasgow Coma Scale score [GCS]≤8) who were admitted during the first 48hours after injury to the Hospital 12 de Octubre from 1987 to 2012. The most relevant radiological findings, surgical procedures, and intracranial monitoring indications reported in the literature were defined and compared in 3 equal time periods (1987-1995, 1996-2004, and 2005-2014). Read More

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http://dx.doi.org/10.1016/j.neucir.2016.11.002DOI Listing
August 2018
6 Reads

Mortality and Prehospital Blood Pressure in Patients With Major Traumatic Brain Injury: Implications for the Hypotension Threshold.

JAMA Surg 2017 Apr;152(4):360-368

Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, Arizona6Department of Child Health, The University of Arizona College of Medicine, Phoenix.

Importance: Current prehospital traumatic brain injury guidelines use a systolic blood pressure threshold of less than 90 mm Hg for treating hypotension for individuals 10 years and older based on studies showing higher mortality when blood pressure drops below this level. However, the guidelines also acknowledge the weakness of the supporting evidence.

Objective: To evaluate whether any statistically supportable threshold between systolic pressure and mortality emerges from the data a priori, without assuming that a cut point exists. Read More

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2016.4686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637731PMC
April 2017
15 Reads

[Conservative management of liver trauma and its complications: current gold-standard].

Cir Pediatr 2016 Jan 25;29(1):19-24. Epub 2016 Jan 25.

Servicio de Cirugía Pediátrica. Hospital Universitario Vall d'Hebron. Barcelona.

Introduction: The liver is the second most frequently involved organ in abdominal trauma in children. The aim of this study was to review the characteristics of liver traumas (LT) in children, its treatment and complications.

Material And Methods: Retrospective study of patients with LT treated between 2010-2014. Read More

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January 2016

Educating Providers in Return-to-Play Suggested Guidelines Postconcussion.

Crit Care Nurs Q 2017 Jan/Mar;40(1):49-58

Department of Health Sciences, Robert Morris University, Moon Township, Pennsylvania (Dr Bires); Heartland Care Partners, Manor Care Health Services, Pittsburgh, Pennsylvania (Dr Leonard); and Information Management Solutions, Management Science Associates, Pittsburgh, Pennsylvania (Mr Thurber).

As the awareness of concussions increases, it is imperative to be able to evaluate, diagnose, and treat concussed individuals properly to prevent further complications or death. The primary purpose of this study was to compare a provider's current awareness and comfort level as it relates to the return-to-play guidelines for concussions. A secondary aim was to evaluate current protocols that are in use and determine whether they coincide with the suggested guidelines. Read More

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http://dx.doi.org/10.1097/CNQ.0000000000000141DOI Listing
April 2017
9 Reads

Assessment of acute head injury in an emergency department population using sport concussion assessment tool - 3rd edition.

Appl Neuropsychol Adult 2018 Mar-Apr;25(2):110-119. Epub 2016 Nov 17.

a Division of Neurosurgery , Hennepin County Medical Center , Minneapolis , Minnesota , USA.

Sport Concussion Assessment Tool version 3 (SCAT-3) is one of the most widely researched concussion assessment tools in athletes. Here normative data for SCAT3 in nonathletes are presented. The SCAT3 was administered to 98 nonathlete healthy controls, as well as 118 participants with head-injury and 46 participants with other body trauma (OI) presenting to the ED. Read More

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http://dx.doi.org/10.1080/23279095.2016.1248765DOI Listing
August 2018
17 Reads

Role of Matrix Metalloproteinases in the Pathogenesis of Traumatic Brain Injury.

Mol Neurobiol 2016 11 5;53(9):6106-6123. Epub 2015 Nov 5.

Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, 07102, USA.

Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Studies revealed that the pathogenesis of TBI involves upregulation of MMPs. MMPs form a large family of closely related zinc-dependent endopeptidases, which are primarily responsible for the dynamic remodulation of the extracellular matrix (ECM). Read More

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http://dx.doi.org/10.1007/s12035-015-9520-8DOI Listing
November 2016
14 Reads