412 results match your criteria Circulation: Cardiovascular Interventions [Journal]


The Circle of Life: Vieussens' Arterial Ring.

JACC Cardiovasc Interv 2019 Feb 7. Epub 2019 Feb 7.

Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2018.12.016DOI Listing
February 2019

Balloon Angioplasty and Stenting for Unilateral Branch Pulmonary Artery Stenosis Improve Exertional Performance.

JACC Cardiovasc Interv 2019 Feb;12(3):289-297

Department of Pediatrics, UCSF Benioff Children's Hospital and the University of California, San Francisco, San Francisco, California.

Objectives: This study sought to determine whether pulmonary artery intervention in patients with unilateral proximal pulmonary artery stenosis (PAS) improves exercise capacity, abnormal ventilatory response to exercise, and symptoms.

Background: Stenosis of the branch pulmonary arteries results in pulmonary blood flow maldistribution (PBFM). The resulting ventilation-perfusion mismatch is associated with an increased ventilatory response to exercise and decreased exercise capacity. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.11.042DOI Listing
February 2019

Acute Coronary Syndrome in Transcatheter Aortic Valve Replacement: Defend the Coronary Circulation.

JACC Cardiovasc Interv 2018 Dec;11(24):2534-2536

Department of Cardiology, OhioHealth, Riverside Methodist Hospital, Columbus, Ohio.

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http://dx.doi.org/10.1016/j.jcin.2018.10.017DOI Listing
December 2018
1 Read

Is Post-Percutaneous Coronary Intervention Fractional Flow Reserve of Value in Chronic Total Occlusions?

Circ Cardiovasc Interv 2018 Nov;11(11):e007360

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007360DOI Listing
November 2018
1 Read

Correction to: Circulation: Cardiovascular Interventions: The First 10 Years.

Authors:

Circ Cardiovasc Interv 2018 Sep;11(9):e000037

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http://dx.doi.org/10.1161/HCV.0000000000000037DOI Listing
September 2018
2 Reads

Mortality in Patients With Out-of-Hospital Cardiac Arrest Undergoing a Standardized Protocol Including Therapeutic Hypothermia and Routine Coronary Angiography: Experience From the HACORE Registry.

JACC Cardiovasc Interv 2018 Sep;11(18):1811-1820

Cardiac Arrest Centre, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany. Electronic address:

Objectives: This study sought to analyze the impact of mandatory therapeutic hypothermia and cardiac catheterization in the absence of overt noncardiac cause of arrest as part of the Hannover Cardiac Resuscitation Algorithm before intensive care admission.

Background: Despite advanced therapies, out-of-hospital cardiac arrest (OHCA) is still associated with high mortality rates. Recently, the TTM (Target Temperature Management 33°C Versus 36°C After Out-of-Hospital Cardiac Arrest)-trial caused severe uncertainty about the efficacy of and need for therapeutic hypothermia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19368798183134
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http://dx.doi.org/10.1016/j.jcin.2018.06.022DOI Listing
September 2018
8 Reads
7.345 Impact Factor

Transcatheter Autologous Transfusion to Maintain Pulmonary Circulation During Balloon Pulmonary Angioplasty.

JACC Cardiovasc Interv 2018 Aug 1;11(16):e127-e128. Epub 2018 Aug 1.

Gungzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2018.05.026DOI Listing
August 2018
18 Reads

Impact of Elective Percutaneous Coronary Intervention on Global Absolute Coronary Flow and Flow Reserve Evaluated by Phase-Contrast Cine-Magnetic Resonance Imaging in Relation to Regional Invasive Physiological Indices.

Circ Cardiovasc Interv 2018 Jul;11(7):e006676

Department of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Ibaraki, Japan (Y. Kanaji, T.Y., R.H., T.M., E.U., M. Hoshino, M.Y., M. Hada, Y. Kanno, T.F., H.O., Y.S., A.S., T.L., T.K.).

Background: Few studies have documented changes in global absolute coronary blood flow and global coronary flow reserve after percutaneous coronary intervention (PCI) in relation to regional physiological measures. Phase-contrast cine-magnetic resonance of the coronary sinus is a promising approach to quantify global absolute coronary blood flow. We aimed to assess the impact of elective PCI on global absolute coronary blood flow and global coronary flow reserve by quantifying coronary sinus flow (CSF) using phase-contrast cine-magnetic resonance in relation to regional physiological indices. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.006676DOI Listing
July 2018
26 Reads

The Future of : Changing, Creating, and Maturing.

Authors:
Sunil V Rao

Circ Cardiovasc Interv 2018 Jul;11(7):e007115

Duke Clinical Research Institute and Duke University Health System, Durham, NC.

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007115DOI Listing
July 2018
10 Reads

Unmasking Myocardial Bridge-Related Ischemia by Intracoronary Functional Evaluation.

Circ Cardiovasc Interv 2018 Jun;11(6):e006247

From the Department of Cardiac, Thoracic and Vascular Sciences, Padova University Hospital, Italy.

Background: Invasive physiological assessment of myocardial bridges (MBs) is largely unsettled. Unlike fractional flow reserve (FFR), instantaneous wave-free ratio (iFR) is a diastole-specific index. As such, its value might not be hampered by systolic pressure overshooting and negative systolic pressure gradient caused by the compression of the tunneled coronary artery. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.006247DOI Listing
June 2018
24 Reads

: The First 10 Years.

Circ Cardiovasc Interv 2018 Jun;11(6):e006901

From the Department of Medicine, Brigham and Women's Hospital, Boston, MA (D.P.F., J.A.L., D.O.W.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.006901DOI Listing
June 2018
8 Reads

Treatment Strategy Change After Routine Pressure Wire Assessment for Coronary Artery Disease: What You See Is "NOT" What You Get.

Authors:
Bon-Kwon Koo

JACC Cardiovasc Interv 2018 02;11(4):366-368

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea; and the Institute on Aging, Seoul National University, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2018.01.227DOI Listing
February 2018
9 Reads

Impact of Routine Invasive Physiology at Time of Angiography in Patients With Multivessel Coronary Artery Disease on Reclassification of Revascularization Strategy: Results From the DEFINE REAL Study.

JACC Cardiovasc Interv 2018 02;11(4):354-365

Department of Cardiovascular Sciences, Policlinico Umberto I Roma, Rome, Italy. Electronic address:

Objectives: This study sought to prospectively assess the impact of routine invasive physiology at the time of angiography on reclassification of therapeutic management of multivessel disease (MVD) patients, and to assess how implementation of instantaneous wave-free ratio (iFR) alters the process.

Background: Routine invasive physiology in intermediate coronary lesions at the time of diagnostic angiography, primarily in patients with single-vessel disease and using fractional flow reserve (FFR), reclassifies coronary revascularization management in 26% to 44% of patients. The role of invasive physiology in patients with MVD is unclear. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.11.030DOI Listing
February 2018
16 Reads

Should We Perform an Immediate Coronary Angiogram in All Patients After Cardiac Arrest?: Insights From a Large French Registry.

JACC Cardiovasc Interv 2018 Feb;11(3):249-256

Paris Cardiovascular Research Center, INSERM Unit 970, Paris, France; Université Paris Descartes-Sorbonne Paris Cité, Paris, France; Paris Sudden Death Expertise Center, Paris, France; Medical Intensive Care Unit, AP-HP, Cochin Hospital, Paris, France. Electronic address:

Objectives: This study sought to assess the relationship between an immediate invasive strategy and survival after an out-of-hospital cardiac arrest (OHCA) of presumed cardiac cause, according to prognosis evaluated on hospital arrival.

Background: An immediate coronary angiogram (CAG) may be associated with better outcome after OHCA in neurologically preserved patients but could be futile in other cases.

Methods: From May 2011 to May 2015, we collected data for all patients admitted in hospital after OHCA in Paris and its suburbs (France). Read More

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http://dx.doi.org/10.1016/j.jcin.2017.09.011DOI Listing
February 2018
44 Reads

Dose-Dependent Cardioprotection of Moderate (32°C) Versus Mild (35°C) Therapeutic Hypothermia in Porcine Acute Myocardial Infarction.

JACC Cardiovasc Interv 2018 Jan;11(2):195-205

Division of Cardiovascular Medicine, Stanford University, Stanford, California; Cardiovascular Institute, Stanford University, Stanford, California.

Objectives: The study investigated whether a dose response exists between myocardial salvage and the depth of therapeutic hypothermia.

Background: Cardiac protection from mild hypothermia during acute myocardial infarction (AMI) has yielded equivocal clinical trial results. Rapid, deeper hypothermia may improve myocardial salvage. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.08.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777183PMC
January 2018
10 Reads

Coronary Embolus: An Underappreciated Cause of Acute Coronary Syndromes.

JACC Cardiovasc Interv 2018 Jan;11(2):172-180

Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address:

Coronary embolism is the underlying cause of 3% of acute coronary syndromes but is often not considered in the differential of acute coronary syndromes. It should be suspected in the case of high thrombus burden despite a relatively normal underlying vessel or recurrent coronary thrombus. Coronary embolism may be direct (from the aortic valve or left atrial appendage), paroxysmal (from the venous circulation through a patent foramen ovale), or iatrogenic (following cardiac intervention). Read More

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http://dx.doi.org/10.1016/j.jcin.2017.08.057DOI Listing
January 2018
8 Reads

Collateral Channel Size and Tortuosity Predict Retrograde Percutaneous Coronary Intervention Success for Chronic Total Occlusion.

Circ Cardiovasc Interv 2018 Jan;11(1):e005124

From the Department of Internal Medicine, National Taiwan University Hospital, Taipei (C.-C.H., C.-S.H., Y.-H.C., M.-S.L., C.-F.Y., H.-L.K.); and Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu (C.-K. L., S.-W.M.).

Background: There is little evidence on how to select an interventional collateral channel (CC) in retrograde chronic total occlusion (CTO) percutaneous coronary intervention. We aimed to identify independent angiographic predictors of CC tracking and technical success in retrograde CTO percutaneous coronary intervention.

Methods And Results: From January 2012 to December 2015, a total of 216 consecutive retrograde CTO percutaneous coronary intervention attempts by a high-volume operator in a tertiary university-affiliated hospital were enrolled. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005124DOI Listing
January 2018
11 Reads

ACIST-FFR Study (Assessment of Catheter-Based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement).

Circ Cardiovasc Interv 2017 Dec;10(12)

From the Stanford University School of Medicine, Department of Medicine, Stanford Cardiovascular Institute, CA (W.F.F., C.S., L.Y., M.D.); Mercy Medical Center, Coon Rapids, MN (J.W.C.); Tibor Rubin VA Medical Center, Long Beach, CA (A.H.S.); Lindner Center for Research and Education, The Christ Hospital, Cincinnati, OH (I.J.S.), University of Minnesota, Minneapolis (G.R.); St. Francis Hospital, Roslyn, NY (A.J.); Cardiovascular Research Foundation, New York, NY (A.J.); and Scripps Clinic, La Jolla, CA (M.J.P.).

Background: Measurement of fractional flow reserve (FFR) to guide coronary revascularization lags despite robust supportive data, partly because of the handling characteristics of traditional coronary pressure wires. An optical pressure-monitoring microcatheter, which can be advanced over a traditional coronary guidewire, facilitates FFR assessment but may underestimate pressure wire-derived FFR.

Methods And Results: In this prospective, multicenter trial, 169 patients underwent FFR assessment with a pressure wire alone and with a pressure microcatheter over the pressure wire. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753822PMC
December 2017
13 Reads

Postocclusional Hyperemia for Fractional Flow Reserve After Percutaneous Coronary Intervention.

Circ Cardiovasc Interv 2017 Dec;10(12)

From the Department of Cardiovascular Medicine, Gifu Heart Center, Japan (Y.K., H.O., T.T., T.H., S.O., H.O., J.K., M.O., H.K., T.S., H.M.); Department of Cardiology, Gifu University Graduate School of Medicine, Japan (M.K.); and Department of Biostatistics and Bioinformatics, Graduate School of Medicine, The University of Tokyo, Japan (A.H.).

Background: Postocclusional hyperemia caused by balloon occlusion is a potential alternative method of inducing hyperemia for measuring post-percutaneous coronary intervention fractional flow reserve (FFR). The aim of this study was to investigate postocclusional hyperemia as a method of inducing hyperemia.

Methods And Results: FFR measured by postocclusional hyperemia (FFRoccl) caused by balloon occlusion after percutaneous coronary intervention was compared with FFR measured by drug-induced hyperemia (FFR measured by intravenous ATP; and FFR measured by intracoronary papaverine injection [FFRpap]) in 98 lesions from 98 patients. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005674DOI Listing
December 2017
5 Reads

Three-Year Outcomes of Surgical Versus Endovascular Revascularization for Critical Limb Ischemia: The SPINACH Study (Surgical Reconstruction Versus Peripheral Intervention in Patients With Critical Limb Ischemia).

Circ Cardiovasc Interv 2017 Dec;10(12)

From the Cardiovascular Center, Kansai Rosai Hospital, Amagasaki, Japan (O.I.); Department of Diabetes Care Medicine (M.T.) and Department of Metabolic Medicine (M.T.), Osaka University Graduate School of Medicine, Suita, Japan; Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan (Y.S.); Division of Vascular Surgery, Department of Surgery, Nagoya University School of Medicine, Japan (A.K.); Department of Plastic Surgery, Kobe University Graduate School of Medicine, Japan (H.T.); and Department of Vascular Surgery, Asahikawa Medical University, Japan (N.A.).

Background: The aim of this study was to compare clinical outcomes between surgical reconstruction and endovascular therapy (EVT) for critical limb ischemia (CLI) in today's real-world settings.

Methods And Results: This multicenter, prospective, observational study registered and followed 548 Japanese CLI patients. The registration was in advance of revascularization; 197 patients were scheduled to receive surgical reconstruction, and the remaining 351 were scheduled to receive EVT. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753823PMC
December 2017
32 Reads

Invasive Assessment of the Coronary Microvasculature: The Index of Microcirculatory Resistance.

Circ Cardiovasc Interv 2017 Dec;10(12)

From the Division of Cardiovascular Medicine, Stanford University, CA.

Traditionally, invasive coronary physiological assessment has focused on the epicardial coronary artery. More recently, appreciation of the importance of the coronary microvasculature in determining patient outcomes has grown. Several invasive modalities for interrogating microvascular function have been proposed. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005361DOI Listing
December 2017
5 Reads

Three-Vessel Assessment of Coronary Microvascular Dysfunction in Patients With Clinical Suspicion of Ischemia: Prospective Observational Study With the Index of Microcirculatory Resistance.

Circ Cardiovasc Interv 2017 Nov;10(11)

From the Division of Cardiovascular Medicine, Stanford University, CA (Y.K., W.F.F., T.N., D.-H.C.); Division of Cardiology, Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Seoul, Republic of Korea (J.M.L.); Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea (J.H.L.); Department of Cardiology, Catharina Hospital Eindhoven, the Netherlands (F.M.Z.); Department of Medicine, Seoul National University Hospital, Republic of Korea (J.-H.J., H.-J.L., B.-K.K.); Department of Medicine, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea (J.-H.D.); Department of Medicine, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea (C.-W.N.); Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, Republic of Korea (E.-S.S.); and Institute of Aging, Seoul National University, Republic of Korea (B.-K.K.).

Background: Difficulty directly visualizing the coronary microvasculature as opposed to the epicardial coronary artery makes its assessment challenging. The goal of this study is to measure the index of microcirculatory resistance (IMR) in all 3 major coronary vessels to identify the clinical and angiographic predictors of an abnormal IMR.

Methods And Results: Ninety-three patients who underwent coronary physiological assessment in all 3 major coronary vessels were prospectively enrolled (59. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.11
Publisher Site
http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005445DOI Listing
November 2017
13 Reads

The ACRA Anatomy Study (Assessment of Disability After Coronary Procedures Using Radial Access): A Comprehensive Anatomic and Functional Assessment of the Vasculature of the Hand and Relation to Outcome After Transradial Catheterization.

Circ Cardiovasc Interv 2017 Nov;10(11)

From the Department of Cardiology (M.A.H.v.L., M.R.H., D.J.v.d.H., K.H.M.O., F.K., N.v.R.) and Department of Plastic Surgery (M.J.P.F.R.), VU University Medical Center, Amsterdam, the Netherlands; Department of Epidemiology and Biostatistics, VU University, Amsterdam, the Netherlands (P.M.v.d.V.); Department of Cardiology (N.M.v.M.) and Department of Cardiothoracic Surgery (Y.J.H.J.T.), Erasmus MC, Rotterdam, the Netherlands; Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands (N.v.R.); and Department of Cardiology, Isala Heart Centre, Zwolle, the Netherlands (M.A.H.v.L.).

Background: The palmar arches serve as the most important conduits for digital blood supply, and incompleteness may lead to digital ischemia when the radial artery becomes obstructed after cardiac catheterization. The rate of palmar arch incompleteness and the clinical consequences after transradial access are currently unknown.

Methods And Results: The vascular anatomy of the hand was documented by angiography in 234 patients undergoing transradial cardiac catheterization. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005753DOI Listing
November 2017
25 Reads

Influence of Contrast Media Dose and Osmolality on the Diagnostic Performance of Contrast Fractional Flow Reserve.

Circ Cardiovasc Interv 2017 Oct;10(10)

From the Stanford University Medical Center, CA (T.N., Y.K., D.-H.C., W.F.F.); Stanford Cardiovascular Institute, CA (T.N., Y.K., D.-H.C., W.F.F.); University of Texas Medical School and Memorial Hermann Hospital, Houston (N.P.J., K.L.G.); Cardiovascular Center Aalst, Belgium (B.D.B.); West of Scotland Heart and Lung Center, Golden Jubilee National Hospital, Clydebank, Scotland (C.B., K.G.O.); British Heart Foundation Glasgow Cardiovascular Research Center, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Scotland (C.B.); Division of Cardiovascular Medicine, Stony Brook University Medical Center, NY (A.J.); Cardiovascular Research Foundation (CFR), New York, NY (A.J.); Catharina Hospital, Eindhoven, the Netherlands (N.H.J.P.); and Eindhoven University of Technology, the Netherlands (N.H.J.P.).

Background: Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine. However, contrast media volume and osmolality may affect the degree of hyperemia and therefore diagnostic performance.

Methods And Results: cFFR, instantaneous wave-free ratio, distal pressure/aortic pressure at rest, and FFR were measured in 763 patients from 12 centers. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.004985DOI Listing
October 2017
23 Reads

Role of Proximal Optimization Technique Guided by Intravascular Ultrasound on Stent Expansion, Stent Symmetry Index, and Side-Branch Hemodynamics in Patients With Coronary Bifurcation Lesions.

Circ Cardiovasc Interv 2017 Oct;10(10)

From the Division of Cardiology, University of Alabama at Birmingham (D.H., A.C., O.A., J.T., A.S., M.A.L.); Suez Canal University, Ismailia, Egypt (D.H.); and Medtech Research Theme, National Heart Centre Singapore and Duke-NUS Medical School (N.F.).

Background: Bench models of coronary bifurcation lesions demonstrated that the proximal optimization technique (POT) expanded the stent and opened the side branch (SB). We investigated the role of POT guided by intravascular ultrasound on the main vessel (MV) stent expansion and SB fractional flow reserve (FFR) in patients with coronary bifurcation lesion.

Methods And Results: In 40 patients with coronary bifurcation lesion, 120 intravascular ultrasound examinations of the MV were performed at baseline, after MV stenting, and POT followed by 95 FFR measurements of the SB. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005535DOI Listing
October 2017
11 Reads

Effect of Elective Percutaneous Coronary Intervention on Hyperemic Absolute Coronary Blood Flow Volume and Microvascular Resistance.

Circ Cardiovasc Interv 2017 Oct;10(10)

From the Department of Cardiovascular Medicine, Tsuchiura Kyodo General Hospital, Japan (Y.K., T.M., T.Y., E.U., M.A., J.M., M.H., M.Y., T.N., M.H., S.I., R.H., Y.K., T.K.) and Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Japan (M.I.).

Background: The hemodynamics involved in the relationship between absolute coronary blood flow (ABF) volume and myocardial resistance (MR) are complex, and the effect of percutaneous coronary intervention (PCI) on their changes remains unclear. The aim of this study was to investigate the differences in hyperemic ABF and MR before and after elective PCI using a thermodilution method.

Methods And Results: We investigated 28 vessels (right coronary artery, 9; left anterior descending coronary artery, 18; left circumflex coronary artery, 1) from 28 patients with stable angina pectoris undergoing elective PCI. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005073DOI Listing
October 2017
16 Reads

Phase 2a Clinical Trial of Mitochondrial Protection (Elamipretide) During Stent Revascularization in Patients With Atherosclerotic Renal Artery Stenosis.

Circ Cardiovasc Interv 2017 Sep;10(9)

From the Division of Nephrology and Hypertension (A.S., S.M.S.H., A.E., C.M.F., L.O.L., S.C.T.) and Department of Radiology (J.F.G., H.B., M.A.M., S.M.), Mayo Clinic, Rochester, MN.

Background: Atherosclerotic renal artery stenosis reduces renal blood flow (RBF) and amplifies stenotic kidney hypoxia. Revascularization with percutaneous transluminal renal angioplasty (PTRA) and stenting often fails to recover renal function, possibly because of ischemia/reperfusion injury developing after PTRA. Elamipretide is a mitochondrial-targeted peptide that binds to cardiolipin and stabilizes mitochondrial function. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659347PMC
September 2017
27 Reads
6.220 Impact Factor

Validation Study of Image-Based Fractional Flow Reserve During Coronary Angiography.

Circ Cardiovasc Interv 2017 Sep;10(9)

From the Cardiovascular Center Aalst, OLV Hospital, Belgium (M.P., B.D.B., P.X.); Rabin Medical Center, Petach Tikva, Israel (I.L., H.V.-A., A.A., O.V., P.C., R.K.); Department of Advanced Biomedical Sciences, Federico II University of Naples, Italy (M.P.); CathWorks Ltd, Ra'anana, Israel (I.L., O.V., Y.L.); Columbia University Medical Center, New York-Presbyterian Hospital (A.J.K., P.C., M.B.L.); and Shaare Zedek Medical Center, Jerusalem, Israel (G.W., Y.A.).

Background: Fractional flow reserve (FFR), an index of the hemodynamic severity of coronary stenoses, is derived from invasive measurements and requires a pressure-monitoring guidewire and hyperemic stimulus. Angiography-derived FFR measurements (FFR) may have several advantages. The aim of this study is to assess the diagnostic performance and interobserver reproducibility of FFR in patients with stable coronary artery disease. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.005259DOI Listing
September 2017
38 Reads

Clinical and Prognostic Value of Post-Stenting FFR.

JACC Cardiovasc Interv 2017 08;10(15):1596

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http://dx.doi.org/10.1016/j.jcin.2017.05.049DOI Listing

Retrograde Chronic Total Occlusion Percutaneous Coronary Intervention Through Ipsilateral Collateral Channels: A Multicenter Registry.

JACC Cardiovasc Interv 2017 08;10(15):1489-1497

Division of Cardiology and Angiology II, University Heart Center Freiburg Bad Krozingen, Bad Krozingen, Germany.

Objectives: The aim of this study was to describe the procedural aspects and outcomes of retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) through ipsilateral collateral channels (ILCs).

Background: Retrograde CTO PCI via ILCs is rarely performed, usually when no other retrograde options exist, and available evidence derives mostly from case reports.

Methods: A large retrospective multinational registry was compiled, including all consecutive patients undergoing retrograde CTO PCI through ILCs at 6 centers between September 2011 and October 2016. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.06.002DOI Listing
August 2017
23 Reads

Prognostic Value of Fractional Flow Reserve Measured Immediately After Drug-Eluting Stent Implantation.

Circ Cardiovasc Interv 2017 Aug;10(8)

From the Hungarian Institute of Cardiology, Budapest, Hungary (Z.P.); University Heart Centre Graz, Medical University Graz, Austria (G.G.T.); Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands (P.A.L.T., N.H.J.P.); Cardiovascular Center Aalst, Belgium (G.G.T., E.B., B.D.B.); Department of Advanced Biomedical Sciences, University of Naples Federico II, Italy (E.B.); Institute of Social and Preventive Medicine, University of Bern, Switzerland (S.A.); Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Switzerland (S.A.); Southampton University Hospital NHS Trust, England (N.C.); Cardiovascular Hospital, Lyon, France (G.R.); Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands (N.H.J.P.); Division of Cardiovascular Medicine, Stanford University Medical Center, CA (W.F.F.); and St. Michael's Hospital, University of Toronto, Canada (P.J.).

Background: The predictive value of fractional flow reserve (FFR) measured immediately after percutaneous coronary intervention (PCI) with drug-eluting stent placement has not been prospectively investigated. We investigated the potential of post-PCI FFR measurements to predict clinical outcome in patients from FAME 1 and 2 trials (Fractional Flow Reserve or Angiography for Multivessel Evaluation).

Methods And Results: All patients of FAME 1 and FAME 2 who had post-PCI FFR measurement were included. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.005233DOI Listing
August 2017
23 Reads

Fractional Flow Reserve: A Powerful and Simple, Yet Nuanced, Tool.

JACC Cardiovasc Interv 2017 07;10(14):1402-1404

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.jcin.2017.05.009DOI Listing
July 2017
7.345 Impact Factor

Accuracy of Fractional Flow Reserve Measurements in Clinical Practice: Observations From a Core Laboratory Analysis.

JACC Cardiovasc Interv 2017 07;10(14):1392-1401

Cardiovascular Research Foundation, New York, New York; St. Francis Hospital, Roslyn, New York. Electronic address:

Objectives: The aim of this study was to compare site-reported measurements of fractional flow reserve (FFR) with FFR analysis by an independent core laboratory (CL).

Background: FFR is an index of coronary stenosis severity that has been validated in multiple trials and is widely used in clinical practice. However, the incidence of suboptimal FFR measurements is unknown. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.03.031DOI Listing
July 2017
21 Reads

Impact of Routine Fractional Flow Reserve on Management Decision and 1-Year Clinical Outcome of Patients With Acute Coronary Syndromes: PRIME-FFR (Insights From the POST-IT [Portuguese Study on the Evaluation of FFR-Guided Treatment of Coronary Disease] and R3F [French FFR Registry] Integrated Multicenter Registries - Implementation of FFR [Fractional Flow Reserve] in Routine Practice).

Circ Cardiovasc Interv 2017 Jun;10(6)

From the Department of Cardiology, University Hospital, Lille, France (E.V.B., F.V.); INSERM U1011, Lille-II-University, France (E.V.B., F.V.); Hospital Fernando da Fonseca, Amadora, Portugal (S.-B.B.); Hospital de Santa Cruz - CHLO, Carnaxide, Portugal (L.R.); Statistical Department, St. Jude Medical Inc, St Paul, MN (J.H.); Hôpital Louis Pradel, Lyon, France (G.R.); INSERM 1060 CARMEN, Claude Bernard University Lyon, France (G.R.); Centro Hospitalar Vila Nova de Gaia, Portugal (L.S.); Clinique Sainte Clotilde, Saint Denis de la Réunion, France (C.P.); Hospital Santa Marta - Centro Hospitalar Lisboa Central, Lisboa, Portugal (R.R.); CHU La Timone, Marseille, France (T.C.); Hospital Garcia de Orta, Almada, Portugal (R.C.); CHU Mondor, Créteil, France (E.T.); Centro Hospitalar Universitário Coimbra, Portugal (E.J.); CH d'Annecy, France (L.B.); Hospital Divino Espirito Santo, Ponta Delgada, Portugal (C.M.); C.H.I.T.S. Hôpital Sainte Musse, Toulon, France (D.B.); Hospital Geral dos Covões - Centro Hospitalar Coimbra, Portugal (M.C.); Centre Hospitalier Haguenau, France (M.H.); Hospital Santa Maria - Centro Hospitalar Lisboa Norte, Portugal (E.O.); Hôpital de la Croix-Rousse, Lyon, France (C.B.); Hospital de Braga, Portugal (J.C.); Institut Pasteur de Lille-INSERM, France (J.D.); Hospital São Teotónio, Viseu, Portugal (J.P.); Hôpital Lariboisière, Paris, France (G.S.); Centro Hospitalar Setúbal, Portugal (N.F.); Centre Hospitalier Valence, France (C.B.); Hospital Santo André - Centro Hospitalar Leiria-Pombal, Portugal (J.G.); Hôpital Albert Schweizer, Colmar, France (N.L.); Hospital Dr. Nélio Mendonça, Funchal, Portugal (B.S.); Centre Hospitalier La Durance, Avignon, France (P.B.); Hospital Geral Santo António - Centro Hospitalar do Porto, Portugal (M.-J.S.); Centre Hospitalier Amiens Sud, Amiens, France (L.L.); Centro Hospitalar São João, Porto, Portugal (J.C.S.); Centro Hospitalar Tâmega e Sousa, Penafiel, Portugal (A.R.); Centro Hospitalar Trás-os-Montes e Alto Douro - Unidade Hospitalar Vila Real, Portugal (L.S.); Hospital Espírito Santo, Évora, Portugal (R.F.); and Hopital Privé d'Antony, France (P.D.).

Background: Fractional flow reserve (FFR) is not firmly established as a guide to treatment in patients with acute coronary syndromes (ACS). Primary goals were to evaluate the impact of integrating FFR on management decisions and on clinical outcome of patients with ACS undergoing coronary angiography, as compared with patients with stable coronary artery disease.

Methods And Results: R3F (French FFR Registry) and POST-IT (Portuguese Study on the Evaluation of FFR-Guided Treatment of Coronary Disease), sharing a common design, were pooled as PRIME-FFR (Insights From the POST-IT and R3F Integrated Multicenter Registries - Implementation of FFR in Routine Practice). Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004296DOI Listing
June 2017
41 Reads

Case of Percutaneous Extracorporeal Femoro-Femoral Bypass for Acute Limb Ischemia From Large Bore Access.

JACC Cardiovasc Interv 2017 06 31;10(12):e109-e110. Epub 2017 May 31.

Division of Cardiology, Temple University Hospital, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2017.03.027DOI Listing
June 2017
4 Reads

Stimulating Extracardiac Collaterals via Right Internal Mammary Artery Occlusion: Another Step Into an Undiscovered Country.

Circ Cardiovasc Interv 2017 Jun;10(6)

From the Department of Medicine, Veterans Administration Long Beach Health Care System and University of California, Irvine.

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005364DOI Listing
June 2017
9 Reads

Effect of Permanent Right Internal Mammary Artery Closure on Coronary Collateral Function and Myocardial Ischemia.

Circ Cardiovasc Interv 2017 Jun;10(6)

From the Department of Cardiology, Bern University Hospital, Switzerland.

Background: The objective of this study is to test the effect of permanent right internal mammary artery device closure on coronary collateral function and myocardial ischemia.

Methods And Results: This was a prospective, open-label clinical trial in 50 patients with coronary artery disease. The primary study end point was coronary collateral flow index as obtained during a 1-minute proximal right coronary artery (RCA) and left coronary artery balloon occlusion at baseline before and at follow-up examination 6 weeks after distal right internal mammary artery device closure. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482561PMC
June 2017
21 Reads

Discordance Between Fractional Flow Reserve and Coronary Flow Reserve: Insights From Intracoronary Imaging and Physiological Assessment.

JACC Cardiovasc Interv 2017 05;10(10):999-1007

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

Objectives: The aim of this study was to investigate the epicardial and microvascular substrates associated with discordances between fractional flow reserve (FFR) and coronary flow reserve (CFR) values.

Background: Discordances between FFR and CFR remain poorly characterized.

Methods: FFR, hyperemic stenosis resistance (HSR), and intravascular ultrasound were performed as indexes of epicardial function and CFR and hyperemic microvascular resistance (HMR) as measures of microvascular function in 94 patients with moderate coronary stenosis. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.03.006DOI Listing
May 2017
30 Reads

Hemodynamic Measurements for the Selection of Patients With Renal Artery Stenosis: A Systematic Review.

JACC Cardiovasc Interv 2017 05;10(10):973-985

Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands. Electronic address:

Interventions targeting renal artery stenoses have been shown to lower blood pressure and preserve renal function. In recent studies, the efficacy of catheter-based percutaneous transluminal renal angioplasty with stent placement has been called into question. In the identification of functional coronary lesions, hyperemic measurements have earned a place in daily practice for clinical decision making, allowing discrimination between solitary coronary lesions and diffuse microvascular disease. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.02.046DOI Listing
May 2017
21 Reads

What Is the Clinical Relevance of the Discordance Between Fractional Flow Reserve and Coronary Flow Reserve?

Authors:
Bon-Kwon Koo

JACC Cardiovasc Interv 2017 05;10(10):1008-1010

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2017.03.038DOI Listing
May 2017
20 Reads

Outcomes After Decompression of the Right Ventricle in Infants With Pulmonary Atresia With Intact Ventricular Septum Are Associated With Degree of Tricuspid Regurgitation: Results From the Congenital Catheterization Research Collaborative.

Circ Cardiovasc Interv 2017 May;10(5)

From the Department of Pediatrics, Emory University School of Medicine, Atlanta, GA (C.J.P., R.S., G.T.N., C.M., M.K.); Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia (A.C.G., D.J.G.); Department of Pediatrics, Baylor College of Medicine, Houston, TX (A.M.Q., S.A.M., H.J.); Division of Cardiology, Children's Hospital of Philadelphia, PA (N.M.); and The Heart Institute, Cincinnati Children's Hospital Medical Center, OH (W.W., L.S.R., B.H.G.).

Background: Outcomes after right ventricle (RV) decompression in infants with pulmonary atresia with intact ventricular septum vary widely. Descriptions of outcomes are limited to small single-center studies.

Methods And Results: Neonates undergoing RV decompression for pulmonary atresia with intact ventricular septum were included from 4 pediatric centers. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004428DOI Listing
May 2017
37 Reads

Collateral Circulation in Chronic Total Occlusions: A Marker of Hope or Hype?

JACC Cardiovasc Interv 2017 05;10(9):915-917

PERFUSE Study Group, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcin.2017.03.009DOI Listing
May 2017
5 Reads

Impact of Collateral Circulation on Survival in ST-Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention With a Concomitant Chronic Total Occlusion.

JACC Cardiovasc Interv 2017 05;10(9):906-914

Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

Objectives: This study sought to compare long-term clinical outcome in ST-segment elevation myocardial infarction (STEMI) patients with a concomitant chronic total occlusion (CTO) with well-developed versus poorly developed collaterals toward the CTO.

Background: In STEMI patients, presence of a CTO is associated with increased morbidity and mortality. CTOs are often (partially) perfused by collateral vessels. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.01.026DOI Listing
May 2017
18 Reads

Cutoff Value and Long-Term Prediction of Clinical Events by FFR Measured Immediately After Implantation of a Drug-Eluting Stent in Patients With Coronary Artery Disease: 1- to 3-Year Results From the DKCRUSH VII Registry Study.

JACC Cardiovasc Interv 2017 05 26;10(10):986-995. Epub 2017 Apr 26.

Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China. Electronic address:

Objectives: This study aimed to investigate the cutoff of post-drug-eluting stent (DES) fractional flow reserve (FFR) for prediction of 1- to 3-year target vessel failure (TVF).

Background: FFR immediately after a DES implantation correlates with clinical events. However, the cutoff of post-DES FFR for predicting long-term clinical events remains understudied. Read More

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http://dx.doi.org/10.1016/j.jcin.2017.02.012DOI Listing
May 2017
43 Reads

Fractional Flow Reserve-Guided Complete Revascularization Improves the Prognosis in Patients With ST-Segment-Elevation Myocardial Infarction and Severe Nonculprit Disease: A DANAMI 3-PRIMULTI Substudy (Primary PCI in Patients With ST-Elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization).

Circ Cardiovasc Interv 2017 Apr;10(4)

From the Department of Cardiology, Rigshospitalet, University of Copenhagen, Denmark (J.L., T.E., S.H., L. Kløvgaard, L.H., F.P., E.J., K.S., O.D.B., H.-H.T., L. Køber, D.E.H.); Department of Cardiology, Roskilde Hospital, Denmark (H.K.); Department of Cardiology, Nykoebing Falster Hospital, Denmark (P.C.); and Department of Cardiology, Aalborg University Hospital, Denmark (J.R., A.B.V., J.A., S.E.J., B.R.).

Background: The impact of disease severity on the outcome after complete revascularization in patients with ST-segment-elevation myocardial infarction and multivessel disease is uncertain. The objective of this post hoc study was to evaluate the impact of number of diseased vessel, lesion location, and severity of the noninfarct-related stenosis on the effect of fractional flow reserve-guided complete revascularization.

Methods And Results: In the DANAMI-3-PRIMULTI study (Primary PCI in Patients With ST-Elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization), we randomized 627 ST-segment-elevation myocardial infarction patients to fractional flow reserve-guided complete revascularization or infarct-related percutaneous coronary intervention only. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004460DOI Listing
April 2017
62 Reads

Saline-Induced Coronary Hyperemia: Mechanisms and Effects on Left Ventricular Function.

Circ Cardiovasc Interv 2017 Apr;10(4)

From the Cardiovascular Center Aalst, Belgium (B.D.B., J.A., P.X., A.F., Y.M., M. Penicka, V.F., M. Pellicano, E.B.); Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy (M. Pellicano, E.B.); University Heart Centre Graz, Austria (G.T.); Experimental Cardiology, Thoraxcenter, Erasmus University Rotterdam, The Netherlands (D.J.D.); Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands (N.H.J.P.); and Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands (N.H.J.P.).

Background: During thermodilution-based assessment of volumetric coronary blood flow, we observed that intracoronary infusion of saline increased coronary flow. This study aims to quantify the extent and unravel the mechanisms of saline-induced hyperemia.

Methods And Results: Thirty-three patients were studied; in 24 patients, intracoronary Doppler flow velocity measurements were performed at rest, after intracoronary adenosine, and during increasing infusion rates of saline at room temperature through a dedicated catheter with 4 lateral side holes. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004719DOI Listing
April 2017
33 Reads

Diagnostic Performance of Resting and Hyperemic Invasive Physiological Indices to Define Myocardial Ischemia: Validation With N-Ammonia Positron Emission Tomography.

JACC Cardiovasc Interv 2017 04 29;10(8):751-760. Epub 2017 Mar 29.

Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea; Institute of Aging, Seoul National University, Seoul, Korea. Electronic address:

Objectives: The authors sought to compare the diagnostic performance of fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), and resting distal coronary artery pressure/aortic pressure (Pd/Pa) using N-ammonia positron emission tomography (PET).

Background: The diagnostic performance of invasive physiological indices was reported to be different according to the reference to define the presence of myocardial ischemia.

Methods: A total of 115 consecutive patients with left anterior descending artery stenosis who underwent both N-ammonia PET and invasive physiological measurement were included. Read More

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http://dx.doi.org/10.1016/j.jcin.2016.12.015DOI Listing
April 2017
57 Reads