413,700 results match your criteria Circulation: Cardiovascular Imaging [Journal]


Effect of Salvia Miltiorrhiza Injection in Patients With Autologous Fat Grafting to the Breast: A Preliminary Comparative Study.

Aesthet Surg J 2018 Dec 12. Epub 2018 Dec 12.

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

Background: Salvia miltiorrhiza (SM) is a herb used in Chinese medicine formulations for promoting blood circulation and minimizing vascular stasis. It has been successfully utilized in treating cardiovascular diseases, such as atherosclerosis, thromboembolism, and angina.

Objective: To study the effect of SM injections in autologous fat grafting to the breast. Read More

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December 2018

Occlusion Outside the Norm: A Unique Case of the Pulseless, Well-Perfused Hand Following Closed Humeral Shaft Fracture.

Orthopedics 2018 Dec 11:1-3. Epub 2018 Dec 11.

Transient arterial injury is a common complication encountered in the management of pediatric supracondylar humerus fractures, often presenting as a pulseless hand that appears well perfused, also known as the "pink, pulseless hand." Arterial injuries in pediatric humeral shaft fractures, on the other hand, are exceedingly rare, especially in closed fractures. The authors report a rare case of a humeral shaft fracture presenting as a pink, pulseless hand. Read More

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December 2018

Suppression of Oxygen Radicals Protects Diabetic Endothelium Damage and Tissue Perfusion in a Streptozotocin-Induced Diabetes Rodent Model.

Ann Plast Surg 2019 Jan;82(1S Suppl 1):S18-S22

Background: Oxygen free radicals play a central role in diabetic angiopathy. This study investigated whether suppression of oxygen radicals could decrease endothelial damage and increase peripheral tissue circulation in a diabetic rodent model.

Methods: Sprague-Dawley rats were treated using streptozotocin to induce diabetes. Read More

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January 2019

[Operative treatment of acute mesenteric ischaemia].

Magy Seb 2018 Dec;71(4):149-154

Általános, Ér- és Plasztikai Sebészeti Osztály, Markusovszky Egyetemi Oktatókórház 9700 Szombathely, Markusovszky Lajos u. 5.

Introduction: The incidence of acute mesenteric ischemia (AMI) appears to be increasing due to aging in the population with increasing prevalence of comorbidities. Despite the wide-scale availability of diagnostic technologies, the timely detection and correct treatment are not ensured. This is due to the fact that the required CT angiography is not immediately performed and that vascular surgical reconstruction can be performed within the short ischemic tolerance window of the bowels amounting 4-6 hours. Read More

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December 2018
3 Reads

[Spontaneous haemothorax - thoracic surgeon and intervention radiologist successful cooperation].

Magy Seb 2018 Dec;71(4):155-162

Mellkassebészeti Részleg, Mellkas- és Érsebészeti Osztály, Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház 3526, Miskolc, Szentpéteri kapu 72-76.

The definition of spontaneous haemothorax is accumulation of blood within the pleural space without trauma or iatrogenic causes. A case of a 17-year-old male patient with a history of multiple abnormal arterial fistulas between systemic circulation and pulmonary circulation as a cause of bleeding is presented. An overview of the causes, the clinical features of haemothorax and the interventional radiological methods that can solve some causes of haemothorax are presented in connection of our case report. Read More

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December 2018

Men's position in family care on situations of chronic illness.

Rev Esc Enferm USP 2018 Dec 10;52:e03398. Epub 2018 Dec 10.

Universidade Federal de Mato Grosso, Programa de Pós-Graduação em Saúde Coletiva, Cuiabá, MT, Brasil.

Objective: To understand the care by men in situations of chronic illness of one or more of his children, based on the dimensions of care.

Method: It was based on a comprehensive approach and on the (re)view of the database of the matrix research to which the study is linked, with emphasis on three experiences of illness, in which the men effectively participated in the family care: two children with sickle cell anemia; son with adrenoleukodystrophy and son with concomitant diseases (cancer and kidney disease).

Results: The analysis diagram of each family demonstrated different ways of caring, explaining the relationship between the dimensions of care by men: social; affective/relational and physical/circulation, as well as the reverberations between these dimensions in the care. Read More

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December 2018

ACUTE GASTROENTERITIS ASSOCIATED WITH NOROVIRUS GII.4 VARIANTS.

Arq Gastroenterol 2018 Jul-Sep;55(3):264-266

Universidade Federal da Bahia (UFBA), Instituto de Ciências da Saúde, Laboratório de Virologia, Salvador, BA, Brasil.

Background: Norovirus (NoV) is an important etiologic agent of acute gastroenteritis and infects individuals of all ages, especially children in Brazil and worldwide. NoV GII.4 was the most prevalent genotype worldwide because of your extensive genetic diversity. Read More

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Essential oils and functional herbs for healthy aging.

Neural Regen Res 2019 Mar;14(3):441-445

School of Pharmacy and Applied Science, La Trobe Institute for Molecular Sciences, La Trobe University, Bendigo, Australia.

As total life expectancy increases, the prevalence of age-related diseases such as diabetes and Alzheimer's disease is also increasing. Many hypotheses about Alzheimer's disease have been developed, including cholinergic neuron damage, oxidative stress, and inflammation. Acetylcholine is a major neurotransmitter in the brain and cholinergic deficits leads to cognitive dysfunction and decline. Read More

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March 2019
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Exosome-like Nanozyme Vesicles for H2O2-responsive Catalytic Photoacoustic Imaging of Xenograft Nasopharyngeal Carcinoma.

Nano Lett 2018 Dec 12. Epub 2018 Dec 12.

Photoacoustic imaging (PAI) is an attractive imaging modality, which is promising for clinical cancer diagnosis due to its advantages on deep tissue penetration and fine spatial resolution. However, few tumor catalytic/responsive PAI strategies are developed. Here, we design an exosome-like nanozyme vesicle for in vivo H2O2-responsive PAI of nasopharyngeal carcinoma (NPC). Read More

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December 2018

Analysis of C3 Nephritic Factors by ELISA.

Authors:
Lillemor Skattum

Methods Mol Biol 2019 ;1901:177-182

Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden.

Autoantibodies to the C3 convertase of the alternative pathway of complement, called C3 nephritic factors (C3NeF), cause persistently low C3 in the circulation and production of C3 degradation fragments due to prolonged stabilization of the C3 convertase. C3NeF are associated with glomerulopathy, acquired partial lipodystrophy, and less frequently with increased susceptibility to meningococcal infection. Analysis of C3NeF is an important part of the diagnostic workup of C3 glomerulopathy, but their identification is difficult presumably due to considerable heterogeneity. Read More

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January 2019

Influenza B in a temperate region of northern India 2010-2016: co-circulation of the two lineages with northern hemispherical seasonality.

Virusdisease 2018 Dec 26;29(4):553-559. Epub 2018 Sep 26.

2National Institute of Virology, Pune, Mahrashtra India.

Scant data exist about the epidemiology of influenza B in India. We set out to address the epidemiology of influenza B in a temperate region of northern India from 2010 to 2016. Outpatient and inpatient surveillance was conducted in patients presenting with acute respiratory infection in a northern Indian hospital from September 2010 till April 2016. Read More

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December 2018

Placental Circulation Intact Trial (PCI-T)-Resuscitation With the Placental Circulation Intact vs. Cord Milking for Very Preterm Infants: A Feasibility Study.

Front Pediatr 2018 27;6:364. Epub 2018 Nov 27.

Department of Neuroscience, Psychology, Drug Research and Child Health, Careggi University Hospital of Florence, Florence, Italy.

Preterm newborns receiving briefly delayed cord clamping or cord milking at birth have better neonatal outcomes. However, the time frame in which both these procedures are performed (< 60 s of life) is too short to explore the possible beneficial effects on early infant postnatal adaptation and outcomes of a prolonged transfusion strategy associated with neonatal respiration. We have designed a randomized, multicenter, controlled two-phase study: phase 1 to assess the feasibility of carrying out the protocol in a large randomized trial, and phase 2 to assess the efficacy of bedside assistance with intact placental circulation for 3 min in comparison to cord milking to improve outcome in the neonatal period; we present here the feasibility and safety phase of the study. Read More

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November 2018

Molecular detection and characterisation of avian paramyxovirus type 1 in backyard chickens and pigeons in Alzintan city of Libya.

Open Vet J 2018 28;8(4):401-405. Epub 2018 Oct 28.

Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Universita, 10, Legnaro, Padova 35020, Italy.

Avian paramyxovirus-1 (APMV-1) is the causative agent of Newcastle Disease which affects many species of birds leading to high mortality and heavy economic losses among poultry industry worldwide. Newcastle disease is endemic in Libya with frequent outbreaks occurring in commercial and backyard poultry. APMV-1 was isolated and characterised during the outbreak in 2013. Read More

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October 2018

Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis.

Oxid Med Cell Longev 2018 13;2018:6053492. Epub 2018 Nov 13.

Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brazil.

The Mediterranean diet, rich in olive oil, is beneficial, reducing the risk of cardiovascular diseases and cancer. Olive oil is mostly composed of the monounsaturated fatty acid omega-9. We showed omega-9 protects septic mice modulating lipid metabolism. Read More

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November 2018

Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion.

Front Microbiol 2018 27;9:2927. Epub 2018 Nov 27.

Laboratory of Food Microbiology, Institute of Food, Nutrition and Health, ETH Zürich, Zürich, Switzerland.

The increasing number of multidrug-resistant bacteria intensifies the need to develop new antimicrobial agents. Endolysins are bacteriophage-derived enzymes that degrade the bacterial cell wall and hold promise as a new class of highly specific and versatile antimicrobials. One major limitation to the therapeutic use of endolysins is their often short serum circulation half-life, mostly due to kidney excretion and lysosomal degradation. Read More

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November 2018

Molecular Epidemiology and Risk Factors of Carbapenemase-Producing Isolates in Portuguese Hospitals: Results From European Survey on Carbapenemase-Producing (EuSCAPE).

Front Microbiol 2018 27;9:2834. Epub 2018 Nov 27.

National Reference Laboratory of Antibiotic Resistances and Healthcare Associated Infections, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal.

In Portugal, the epidemiological stage for the spread of carbapenemase-producing (CPE) increased from sporadic isolates or single hospital clones (2010-2013), to hospital outbreaks, later. Here we report data from a 6-month study performed under the European Survey on Carbapenemase-Producing (EuSCAPE). During the study period, 67 isolates (61 and 6 ) non-susceptible to carbapenems were identified in participant hospital laboratories. Read More

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November 2018

Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts.

Int J Nanomedicine 2018 19;13:7647-7656. Epub 2018 Nov 19.

Department of Micro- and Nanotechnology, DTU Nanotech, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark,

Background: Active, ligand-mediated, targeting of functionalized liposomes to folate receptors (FRs) overexpressed on cancer cells could potentially improve drug delivery and specificity. Studies on folate-targeting liposomes (FTLs) have, however, yielded varying results and generally fail to display a clear benefit of FR targeting.

Method: Tumor accumulating potential of FTLs and NTLs were investigated in a FR overex-pressing xenograft model by positron emission tomography/computed tomography imaging. Read More

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November 2018

Design Optimization of Tumor Vasculature-Bound Nanoparticles.

Sci Rep 2018 Dec 11;8(1):17768. Epub 2018 Dec 11.

Department of Mechanical Engineering, McGill University, Montreal, Quebec, Canada.

Nanotherapy may constitute a promising approach to target tumors with anticancer drugs while minimizing systemic toxicity. Computational modeling can enable rapid evaluation of nanoparticle (NP) designs and numerical optimization. Here, an optimization study was performed using an existing tumor model to find NP size and ligand density that maximize tumoral NP accumulation while minimizing tumor size. Read More

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December 2018

Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity.

Sci Rep 2018 Dec 11;8(1):17772. Epub 2018 Dec 11.

School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.

Given the association between high aerobic capacity and the prevention of metabolic diseases, elucidating the mechanisms by which high aerobic capacity regulates whole-body metabolic homeostasis is a major research challenge. Oxidative post-translational modifications (Ox-PTMs) of proteins can regulate cellular homeostasis in skeletal and cardiac muscles, but the relationship between Ox-PTMs and intrinsic components of oxidative energy metabolism is still unclear. Here, we evaluated the Ox-PTM profile in cardiac and skeletal muscles of rats bred for low (LCR) and high (HCR) intrinsic aerobic capacity. Read More

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December 2018

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity.

Blood Adv 2018 Dec;2(23):3540-3552

Department of Medicine and.

Megakaryocyte (MK) migration from the bone marrow periosteal niche toward the vascular niche is a prerequisite for proplatelet extension and release into the circulation. The mechanism for this highly coordinated process is poorly understood. Here we show that dynasore (DNSR), a small-molecule inhibitor of dynamins (DNMs), or short hairpin RNA knockdown of DNM2 and DNM3 impairs directional migration in a human MK cell line or MKs derived from cultured CD34 cells. Read More

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December 2018

Local injection of tissue-plasminogen activator using a pulse spray catheter as a treatment option for proximal deep vein thrombosis: A case report.

J Cardiol Cases 2014 Nov 27;10(5):163-166. Epub 2014 Jun 27.

Showa University Northern Yokohama Hospital, Division of Cardiology and Cardiac Catheterization Laboratories, Yokohama, Japan.

A 24-year-old woman was admitted to our hospital with the diagnosis of pulmonary thromboembolism (PTE) and left common iliac vein thrombosis. She had used low-dose contraceptive pill for dysmenorrhea. Otherwise, her laboratory data did not show any other thrombotic risk factors. Read More

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November 2014
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Use of therapeutic hypothermia and extracorporeal life support after an unusual response to the ajmaline challenge in a patient with Brugada syndrome.

J Cardiol Cases 2014 Jul 1;10(1):34-38. Epub 2014 May 1.

Department of Cardiology, Hospital Clínic de Barcelona, Spain.

Background: Brugada syndrome is a cardiac disorder associated with a high risk of sudden cardiac death, especially in young subjects. The incidence and prevalence are likely underestimated. The diagnosis is based on a characteristic electrocardiography (ECG) pattern. Read More

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Truncus arteriosus 5th decade transesophageal and transthoracic echocardiogram features.

J Cardiol Cases 2014 Jul 17;10(1):25-30. Epub 2014 May 17.

Andrews Memorial Hospital, TAI Wing, 27 Hope Road, Kingston 10, Jamaica.

Persistent truncus arteriosus in the 5th decade is a rare entity as the only physical anomaly. Truncus arteriosus consists of a single great arterial trunk with the systemic, pulmonary, and coronary circulation, with no atretic aortic or pulmonary vessel. The complex cardiac anatomy can be delineated with transesophageal and transthoracic echocardiography, as is illustrated the case of our patient, who was diagnosed in infancy, at 5 months of age. Read More

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Abolished ischemic tricuspid regurgitation by revascularization of left anterior descending artery: The role of collateral circulation.

J Cardiol Cases 2014 Jul 1;10(1):9-12. Epub 2014 May 1.

Department of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.

A 74-year-old man presented with recent inferior wall myocardial infarction. The right ventricle (RV) was strikingly dilated and akinetic along the free wall compatible with right ventricular infarction. Accordingly, severe functional tricuspid regurgitation (TR) was detected. Read More

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Successful percutaneous flow redirection to the juvenile patient of fulminant myocarditis treated with percutaneous cardio-pulmonary support.

J Cardiol Cases 2012 Aug 13;6(2):e55-e58. Epub 2012 Jun 13.

Department of Cardiovascular Medicine and Advanced Cardiovascular Center, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.

Percutaneous cardio-pulmonary support (PCPS) system is a powerful life support system for acute circulation failure. This life support system requires more than a fourteen-French cannula to the artery. Insertion with such a large tube sometimes induces damage to the peripheral circulation. Read More

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Transient left ventricular apical ballooning in a patient with cardiac arrest after subarachnoid hemorrhage.

J Cardiol Cases 2011 Feb 1;3(1):e33-e36. Epub 2011 Feb 1.

Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Subarachnoid hemorrhage (SAH) often accompanies cardiac abnormalities. Sudden cardiac arrest is also known to occur after SAH. A 32-year-old woman was admitted to our hospital because of cardiac arrest immediately after the onset of SAH. Read More

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February 2011

Circulation Research.

Authors:

Circ Res 2017 Jan;120(1)

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January 2017

ECG Challenge: June 9, 2015.

Authors:

Circulation 2015 Jun;131(23):2092

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Circulation: Clinical Summaries.

Authors:

Circulation 2015 Jun;131(23):2027-2028

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ECG Challenge: February 3, 2015.

Authors:

Circulation 2015 Feb;131(5):513

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February 2015

Circulation: Clinical Summaries.

Authors:

Circulation 2015 Feb;131(5):443-444

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February 2015

Circulation: Clinical Summaries.

Authors:

Circulation 2015 Feb;131(6):517-518

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February 2015

Circulation: Cardiovascular Imaging.

Authors:

Circ Cardiovasc Imaging 2016 Jan;9(1):e000011

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January 2016

Distal Thrombectomy for Acute Anterior Circulation Stroke with Chronic Large Vessel Occlusion.

World Neurosurg 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, Shandong, China. Electronic address:

Background: Endovascular therapy has been increasingly recommended for the treatment of acute ischemic stroke with large vessel occlusion of the anterior circulation. However, occlusions of the distal cerebral artery are not uncommon and may cause clinical deficits, especially when combined with ipsilateral chronic large vessel occlusion. Therefore, in this patient population, the recognition of chronic occlusion and recanalization of the distal occlusive artery might be of great value for flow compensation. Read More

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December 2018
1 Read

Developing a quality standard for verbal communication during CABG procedures.

Semin Thorac Cardiovasc Surg 2018 Dec 8. Epub 2018 Dec 8.

Department of Cardio-Thoracic Surgery, Leiden University Medical Center, Leiden.

Objective: Verbal communication during coronary artery bypass graft (CABG) procedures is essential for safe and efficient cardiac surgery, yet sensitive to failure due to a current lack of standardization. The goal of this study was to improve communication during CABG by identifying critical items in verbal interaction between surgeons, anesthetists and perfusionists.

Methods: Based on 6 video recordings, a list was assembled containing items of communication in CABG procedures. Read More

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December 2018
1 Read

Contrast-enhanced ultrasonography is a feasible technique for quantifying hepatic microvascular perfusion in dogs with extrahepatic congenital portosystemic shunts.

Vet Radiol Ultrasound 2018 Dec 9. Epub 2018 Dec 9.

Laboratory of Veterinary Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.

Extrahepatic-congenital portosystemic shunt is a vascular anomaly that connects the portal vein to the systemic circulation and leads to a change in hepatic microvascular perfusion. However, an assessment of hepatic microvascular perfusion is limited by conventional diagnostic modalities. The aim of this prospective, exploratory study was to assess hepatic microvascular perfusion in dogs with extrahepatic-congenital portosystemic shunt using contrast-enhanced ultrasonography (CEUS) using perfluorobutane (Sonazoid ). Read More

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December 2018

Projected changes in wind assistance under climate change for nocturnally migrating bird populations.

Glob Chang Biol 2018 Dec 9. Epub 2018 Dec 9.

Cornell Laboratory of Ornithology, Cornell University, Ithaca, New York.

Current climate models and observations indicate that atmospheric circulation is being affected by global climate change. To assess how these changes may affect nocturnally migrating bird populations, we need to determine how current patterns of wind assistance at migration altitudes will be enhanced or reduced under future atmospheric conditions. Here, we use information compiled from 143 weather surveillance radars stations within the contiguous United States to estimate the daily altitude, density, and direction of nocturnal migration during the spring and autumn. Read More

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December 2018

Models.

Acta Physiol (Oxf) 2018 Dec 7:e13237. Epub 2018 Dec 7.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Vegetative Physiology.

A look at the history of science supports this statement. Harvey's discovery of the blood circulation, published in 1628, is undoubtedly among the most important events in the history of physiology. Although Harvey's concept of blood circulation was brilliant at that time, it was far away from a comprehensive insight into the circulatory system. Read More

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December 2018
1 Read

Hematopoietic cell-specific lyn substrate (HCLS1 or HS1): A versatile actin-binding protein in leukocytes.

J Leukoc Biol 2018 Dec 11. Epub 2018 Dec 11.

Department of Molecular Biomedicine, CINVESTAV-IPN, Mexico City, Mexico.

Leukocytes are constantly produced in the bone marrow and released into the circulation. Many different leukocyte subpopulations exist that exert distinct functions. Leukocytes are recruited to sites of inflammation and combat the cause of inflammation via many different effector functions. Read More

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December 2018

Early Endovascular Thrombectomy for Large Vessel Ischemic Stroke Reduces Disability at 90 Days.

Acad Emerg Med 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurology, University of Minnesota, Minneapolis, Minnesota.

Anterior circulation large vessel occlusion (LVO) of the internal carotid or middle cerebral artery is one of the most devastating ischemic stroke subtypes. Prior to 2015, evidence supporting endovascular thrombectomy for acute ischemic stroke was limited. This was due to multiple factors, including low recanalization rates with previous generation thrombectomy devices, inadequate neuroimaging inclusion criteria (patients enrolled in trials lacked target LVO and/or had large pre-existing core infarcts), and selection bias-patients considered most likely to benefit from thrombectomy underwent the procedure outside of clinical trials. Read More

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December 2018
1 Read

HMGB1+ microparticles present in urine are hallmarks of nephritis in patients with systemic lupus erythematosus.

Eur J Immunol 2018 Dec 10. Epub 2018 Dec 10.

Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70 No 52-21, Medellín, Colombia.

Non-classical monocytes infiltrate the kidney parenchyma and participate in tissue damage in patients with lupus nephritis (LN). Circulating microparticles (MPs) seem to play critical roles in the activation of monocytes in systemic lupus erythematosus (SLE) patients. This study aims to characterize the phenotypes of MPs and monocyte subsets in LN patients and to determine their potential to discriminate between SLE patients with and without LN. Read More

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December 2018
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Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia.

Cochrane Database Syst Rev 2018 Dec 8;12:CD009195. Epub 2018 Dec 8.

Department of Medical Imaging, Gold Coast University Hospital, 1 Hospital Blvd, Southport, Queensland, Australia, 4215.

Background: Chronic limb-threatening ischaemia (CLTI) is a manifestation of peripheral arterial disease (PAD) that includes chronic ischaemic rest pain or ischaemic skin lesions, ulcers, or gangrene for longer than two weeks. The severity of the disease depends on the extent of arterial stenosis and the availability of collateral circulation. Treatment for CLTI aims to relieve ischaemic pain, heal ischaemic ulcers, prevent limb loss, improve quality of life, and prolong survival. Read More

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December 2018
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Genome sequence characterization of canine parvoviruses prevalent in the Sichuan province of China.

Transbound Emerg Dis 2018 Dec 11. Epub 2018 Dec 11.

China Animal Health and Epidemiology Center, Qingdao, Shandong Province, China.

Canine parvovirus 2 (CPV-2) infection is responsible for large numbers of animal deaths worldwide and is one of the most dangerous infectious diseases in young puppies. Twenty-four rectal swabs were collected from dogs with clinical signs of vomiting and hemorrhagic diarrhea and were initially verified to be infected with CPV-2 using colloidal gold test strips. From the 24 CPV-positive samples, complete genome of 5050-5054 nucleotides was sequenced with a next-generation sequencing platform. Read More

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December 2018

Immediate remote ischemic postconditioning reduces cerebral damage in ischemic stroke mice by enhancing leptomeningeal collateral circulation.

J Cell Physiol 2018 Dec 10. Epub 2018 Dec 10.

Beijing Key Laboratory of Hypoxia Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.

Remote ischemic postconditioning (RIPC) is a promising neuroprotective strategy for ischemic stroke. Here, we employed a focal ischemic stroke mouse model to test the hypothesis that poststroke collateral circulation as a potent mechanism of action underlying the therapeutic effects of immediate RIPC. During reperfusion of cerebral ischemia, the mice were randomly assigned to receive RIPC, granulocyte colony-stimulating factor (G-CSF) as a positive control, or no treatment. Read More

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December 2018

Progress of polio eradication and containment requirements after eradication.

Authors:
M Steven Oberste

Transfusion 2018 Dec;58 Suppl 3:3078-3083

Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

Wild poliovirus (WPV) is nearing eradication, and only three countries have never interrupted WPV transmission (Pakistan, Afghanistan, and Nigeria). WPV2 was last detected in 1999, and it was declared eradicated in 2015. WPV3 has not been detected since 2012. Read More

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December 2018
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Immunoglobulins and virus antibody titers: of past needs, current requirements, and future options.

Transfusion 2018 Dec;58 Suppl 3:3090-3095

Global Pathogen Safety, Shire (previously Baxter BioScience, Baxalta), Vienna, Austria.

Background: Immunoglobulins (Igs) have been in clinical use for almost 70 years, and early on were also used in conjunction with exposure to the measles virus or polio virus. The US regulations that describe functional Ig lot release thus require the demonstration of minimum antibody titers against these two viruses, although the use of vaccines has now dramatically reduced their incidence. The lower clinical importance of these viruses raises the question of whether other virus antibodies might be more informative for patients with immunodeficiency. Read More

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December 2018

Model and Application to Support the Coronary Artery Diseases (CAD): Development and Testing.

Interdiscip Sci 2018 Dec 7. Epub 2018 Dec 7.

Bioengineering Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

Cardiovascular diseases are among the main causes of morbidity, disability, and mortality. Most of them occur because of an atherosclerotic plaque developing within a coronary artery, which can cause a narrowing of the vessel lumen (coronary stenosis) or even break it. It is, therefore, useful to evaluate the role of the stress state of the endothelial layer of the arterial tissue, both for the maintenance of the blood circulation and for the implications in presence of a pathology that can lead to thromboembolic complications. Read More

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December 2018

Imaging and Surgical Treatment of Primary Pulmonary Artery Sarcoma.

Int J Cardiovasc Imaging 2018 Dec 8. Epub 2018 Dec 8.

Houston Methodist DeBakey Heart and Vascular Center, Houston, TX, USA.

Primary pulmonary artery sarcoma is a rare tumor originating from the pulmonary artery tree. Given the low incidence, few centers have reported on more than a handful of cases. Because of its rarity it is also commonly misdiagnosed as pulmonary embolism. Read More

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December 2018

Bone Marrow Transplantation for Treatment of the Col1a2 Osteogenesis Imperfecta Mouse Model.

Calcif Tissue Int 2018 Dec 8. Epub 2018 Dec 8.

Orthopaedic Research and Biotechnology Unit, Kids Research, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

Bone marrow transplantation (BMT) of healthy donor cells has been postulated as a strategy for treating osteogenesis imperfecta (OI) and other bone fragility disorders. The effect of engraftment by tail vein injection and/or marrow ablation by 6 Gy whole body irradiation were tested in Col1a2 (OI) mice as a model of mild-moderate OI. Dual-emission X-ray absorptiometry, microCT, and 4-point bending were used to measure bone volume (BV), bone mineral density (BMD), and biomechanical strength. Read More

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December 2018

Gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF‑κB signaling pathways.

Mol Med Rep 2018 Dec 4. Epub 2018 Dec 4.

Department of Vascular Surgery, The First Hospital of Qiqihar City, Qiqihar, Heilongjiang 161021, P.R. China.

Gamboge is the dry resin secreted by Garcinia hanbaryi Hook.f, with the function of promoting blood circulation and anti‑cancer effects, detoxification, hemostasis and killing insects. It is also used for the treatment of cancer, brain edema and other diseases. Read More

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December 2018