- Tais Hitomi Wakamatsu,
- Ana Estela Besteti Pires Ponce SantʼAnna,
- Priscila Cardoso Cristovam,
- Venâncio Avancini Ferreira Alves,
- Alda Wakamatsu,
- José Alvaro Pereira Gomes
Cornea 2017 Sep 15. Epub 2017 Sep 15.
*Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil; and †Department of Pathology, LIM 14, São Paulo University School of Medicine, São Paulo, Brazil.
Dry eye is a multifactorial disease comprising a wide spectrum of ocular surface alterations and symptoms of discomfort. In most patients with aqueous-deficient dry eye, pharmaceutical tear substitutes are used to control symptoms and prevent ocular surface damage. However, in severe dry eye conditions caused by cicatricial disorders, such as Stevens-Johnson syndrome and ocular cicatricial mucous membrane pemphigoid, noninvasive treatments are insufficient, and patients are at risk of developing complications that can lead to blindness. Read More