4,126 results match your criteria Cicatricial Pemphigoid
J Pediatr Urol 2018 Nov 22. Epub 2018 Nov 22.
Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, Largo Gaslini 5, 16147, Genoa, Italy; DINOGMI, University of Genoa, Genoa, Italy. Electronic address:
Introduction: Ureteropelvic junction obstruction (UPJO) is one of the most common urological diseases in children. The etiology can be intrinsic, extrinsic (crossing vessel [CV] or adhesions), or mixed. To date, ultrasonography and scintigraphy are considered gold-standard imaging techniques for the study of UPJO. Read More
Angiol Sosud Khir 2018 ;24(4):185-190
Department for General Surgery and Urology, Volgograd State Medical University under the RF Ministry of Public Health, Volgograd, Russia.
The article is a literature review containing a detailed description of anticoagulant therapy variants, their efficacy in recanalization of deep veins, as well as patients' compliance to treatment. Russian specialists have demonstrated that the processes of active re-organization of thrombotic masses, in some cases leading to complete clearing of the vessel's lumen from a thrombus, may be observed at terms from 3 to 6 months, with a failure to occur within the above period reportedly followed by formation of irreversible cicatricial-sclerotic alterations in the veins. That is why adequate anticoagulant therapy should be initiated promptly in order to prevent the development of irreversible alterations and a decompensated form of chronic venous insufficiency. Read More
Khirurgiia (Mosk) 2018 (11):11-19
Sechenov First Moscow State Medical University, Moscow, Russia.
Aim: To analyze long-term outcomes of tracheal transplantation.
Material And Methods: There were 1128 patients with cicatricial tracheal stenosis who have been operated at the Petrovsky Russian Research Center for Surgery and the Sechenov First Moscow State Medical University for the period 1963-2015.
Results: Operations have become safer. Read More
Vestn Oftalmol 2018 ;134(5. Vyp. 2):270-275
Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, Chair of Ophthalmology, 8-2 Malaya Trubetskaya St., Moscow, Russian Federation, 119991.
The article reviews the literature devoted to modern intraoperative methods of preventing cicatricial process at the site of dacryostoma after endonasal endoscopic dacryocystorhinostomy. Despite the constant improvement of the surgery technique, complications in the postoperative period still occur. They include the formation of granulation tissue at the sites of dacryostoma, synechiae in the nasal cavity, or narrowing of the dacryostoma, which ultimately leads to a relapse of the disease. Read More
Mali Med 2018 ;33(2):13-16
Faculté de médecine et d'Odontostomatologie.
Introduction: Prurigo is one of the most common dermatological conditions during HIV infection and AIDS. It appears as an immunosuppression marker associated with HIV infection. The study objective was to determine the prevalence of prurigo in people living with the human immunodeficiency virus (PLHIV) in Fousseyni N'Daou Hospital of Kayes, and to describe the socio-demographic aspects of patients and lesions associated with prurigo among PLHIV. Read More
J Am Osteopath Assoc 2018 Dec;118(12):824-826
Sarcoidosis is a granulomatous condition that has a highly variable presentation. One rare presentation of sarcoidosis is cutaneous scalp sarcoidosis. Usually scalp sarcoid presents as a scarring alopecia, but it can be nonscarring. Read More
J Burn Care Res 2018 Nov 15. Epub 2018 Nov 15.
Vanderbilt University Medical Center, Department of Otolaryngology, Nashville, TN, USA.
Introduction: Inhalation injury is an independent risk factor in burn mortality, imparting a 20% increased risk of death. Yet there is little information on the natural history, functional outcome, or pathophysiology of thermal injury to the laryngotracheal complex, limiting treatment progress.
Methods: Case series (n=3) of significant thermal airway injury. Read More
Australas J Dermatol 2018 Nov 15. Epub 2018 Nov 15.
Servicio de Dermatología, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Background/objectives: Frontal fibrosing alopecia (FFA) is a scarring alopecia whose prevalence is increasing. The pathogenesis of this disease is not well known. Genetic, environmental, hormonal and autoimmunity related factors have been considered; however, only a few cases of familial frontal fibrosing alopecia have been reported. Read More
Burns 2018 Nov 11. Epub 2018 Nov 11.
Universidade Federal de São Paulo (UNIFESP/EPM) - Plastic Surgery Division, São Paulo, Brazil.
Background/objectives: Keloid is a healing disorder that occurs exclusively in humans. This pathology is considered a benign cicatricial neoplasm, whose physiopathogenesis has not yet completely clarified. Its disfiguring appearance often could potentially cause a disturbance in the patient regarding his/her body image. Read More
J Dermatolog Treat 2018 Nov 9:1-28. Epub 2018 Nov 9.
a Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences , Tehran , Iran .
Lichen planopilaris (LPP) is an immune-mediated cicatricial alopecia. The main clinical presentations of LPP include classic form, frontal fibrosing alopecia (FFA), and Graham-Little-Piccardi-Lassueur syndrome (GLPLS). We reviewed medical records of all 291 patients diagnosied with LPP from 2006 to 2017 in Department of Dermatology, Tehran University of Medical Sciences. Read More
Skin Appendage Disord 2018 Oct 20;4(4):308-311. Epub 2018 Apr 20.
Universidade Federal Fluminense, Niterói, Brazil.
Brunsting-Perry type pemphigoid (BPP) is a rare subepidermal blistering disease and a cause of secondary cicatricial alopecia. It was originally described by Brunsting and Perry in 1957 as a rare variant of cicatricial pemphigoid, characterized by bullous lesions limited to the head, neck, scalp, and upper trunk with mild or no mucosal involvement. We report 2 cases of BPP cicatricial alopecia with histopathology of subepidermal blister formation, different clinical presentation, and different salt-split test results. Read More
J Am Acad Dermatol 2018 Oct 27. Epub 2018 Oct 27.
Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:
Acta Ophthalmol 2018 Nov 2. Epub 2018 Nov 2.
Department of Oculoplastic and Orbital Surgery, Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Purpose: To report on the outcomes of our preferred surgical technique for the correction of lower eyelid cicatricial ectropion METHODS: We conducted a retrospective, nonrandomized, interventional analysis of a consecutive case series of patients with cicatricial lower lid ectropion treated with adhesiolysis, lateral eyelid-block excision with canthoplasty and full-thickness skin grafting. Donor sites included the ipsi- or contralateral upper eyelid and pre- or retroauricular skin. All patients were treated by one of our oculoplastic surgeons in the period from January 2005 to January 2017 in the Rotterdam Eye Hospital/Focus Clinic Rotterdam. Read More
Int J Trichology 2018 Jul-Aug;10(4):162-168
Department of Dermatology, The Royal London Hospital, Barts Health NHS Trust, London, UK.
Context: Frontal fibrosing alopecia (FFA) is a primary cicatricial alopecia characterized by progressive recession of frontal, and often temporoparietal, hairline mainly in postmenopausal women. Currently, there are no guidelines or proposed evidence-based treatment for FFA.
Aims: The aim of this study was to retrospectively evaluate the effect and safety of intralesional triamcinolone acetonide injections (ITAIs) either as monotherapy or as concomitant treatment in the management of hairline recession in FFA. Read More
Exp Dermatol 2018 Oct 31. Epub 2018 Oct 31.
Department of Dermatology, Tokyo Medical University.
Lichen planopilaris (LPP) is a primary cicatricial alopecia characterized by the infiltration of lymphocytes in the upper portion of hair follicles. Inflammation around the bulge region of hair follicles induces destruction of hair follicle stem cells and tissue fibrosis, resulting in permanent hair loss. Treatment is still challenging, and the precise pathophysiology of this disorder is unknown. Read More
PLoS One 2018 29;13(10):e0205775. Epub 2018 Oct 29.
The Jackson Laboratory, Bar Harbor, Maine, United States of America.
In a large scale screen for skin, hair, and nail abnormalities in null mice generated by The Jackson Laboratory's KOMP center, homozygous mutant Far2tm2b(KOMP)Wtsi/2J (hereafter referrred to as Far2-/-) mice were found to develop focal areas of alopecia as they aged. As sebocytes matured in wildtype C57BL/NJ mice they became pale with fine, uniformly sized clear lipid containing vacuoles that were released when sebocytes disintegrated in the duct. By contrast, the Far2-/- null mice had sebocytes that were similar within the gland but become brightly eosinophilic when the cells entered the sebaceous gland duct. Read More
Ophthalmic Plast Reconstr Surg 2018 Oct 24. Epub 2018 Oct 24.
Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, Ohio, U.S.A.
Purpose: To describe a novel technique to correct cicatricial lower lid entropion and retraction using a transverse lower lid tarsotomy with an interposed tarsoconjunctival flap posterior lamellar spacer.
Methods: Technique description and retrospective interventional case series.
Results: Four patients underwent the procedure-two with complications following treatment of sinonasal carcinoma and two with complications following orbital fracture repair. Read More
Australas J Dermatol 2018 Oct 25. Epub 2018 Oct 25.
Barton Specialist Centre, Barton, Australian Capital Territory, Australia.
Frontal fibrosing alopecia (FFA) is a primary patterned cicatricial alopecia with a complicated pathogenesis yet to be fully understood. FFA appears to be increasing in incidence worldwide, especially in the last decade. In order to consider current treatment options, we reviewed current evidence for its pathogenesis comprising immune-mediated, genetic, hormonal and environmental factors. Read More
Eur J Ophthalmol 2018 Oct 25:1120672118805622. Epub 2018 Oct 25.
Ophthalmic Plastic Surgery Service, LV Prasad Eye Institute, Hyderabad, India.
Aim:: To test if hyaluronic acid gel injection in the upper eyelid achieves correction of congenital cicatricial ectropion and reduction in lagophthalmos, in preparation for intraocular surgery.
Methods:: This case reports the long-term outcome of hyaluronic acid gel injection in the upper eyelid for the correction of ectropion prior to cataract surgery. One millilitre of hyaluronic acid gel was injected in both the upper eyelids of a child with congenital ichthyosis in the suborbicularis plane, prior to cataract surgery. Read More
Int J Pharm 2018 Dec 6;552(1-2):340-351. Epub 2018 Oct 6.
Laboratório de Tecnologia e Desenvolvimento de Compósitos e Materiais Poliméricos (LaCoPol), Universidade Federal de Pelotas (UFPel), Campus Capão do Leão s/n, 96010-900 Pelotas, RS, Brazil. Electronic address:
Wound healing can be a painful and time-consuming process in patients with diabetes mellitus. In light of this, the use of wound healing devices could help to accelerate this process. Here, cellulose-based films loaded with vitamin C (VitC) and/or propolis (Prop), two natural compounds with attractive properties were engineered. Read More
Gastroenterol Hepatol 2018 Oct 3. Epub 2018 Oct 3.
Servicio de Aparato Digestivo, Hospital Universitario San Cecilio, Granada, España.
Acta Histochem 2018 Nov 29;120(8):837-845. Epub 2018 Sep 29.
Charité-Universitätsmedizin, Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science, Berlin, Germany.
Dysregulation of the mammalian target of rapamycin (mTOR) signaling pathway has a variety of effects on the immune system and stem cell proliferation. Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are inflammatory scalp conditions resulting in permanent alopecia, which are thought to be related to stem cell damage. Here we investigate the expression of mTOR signaling pathway proteins in human hair follicles of LPP and FFA patients. Read More
Dermatol Ther 2018 Nov 27;31(6):e12656. Epub 2018 Sep 27.
Department of Dermatology, Columbia University Medical Center, New York, New York.
Lichen planopilaris (LPP) is an inflammatory cicatricial alopecia for which many different therapies are attempted with varying success. The Janus kinase (JAK) inhibitor, tofacitinib, has been shown to be effective in treating the noncicatricial alopecia, alopecia areata. As in alopecia areata, upregulation of interferon and JAK signaling may play a role in LPP. Read More
Dermatol Online J 2018 Jul 15;24(7). Epub 2018 Jul 15.
Department of Dermatology and Venereology, Centro Hospitalar Sao Joao, EPE Porto.
Porocarcinoma (PC) is a malignant neoplasm arising from the intraepidermal ductal portion of the sweat gland duct. Lichen planopilaris (LPP) is a not so rare variant of cutaneous lichen planus (LP) with a preferential involvement of hair follicles, consisting of a chronic lymphocytic inflammation, leading to cicatricial alopecia. A 42-year-old woman, recently diagnosed with HIV infection, was referred to our clinic because of an alopecic patch of 6 years' duration. Read More
Clin Exp Dermatol 2018 Sep 26. Epub 2018 Sep 26.
Dermatology Department, Hospital Universitario Ramon y Cajal, Madrid, Spain.
Background: Frontal fibrosing alopecia (FFA) is a chronic cicatricial alopecia with an increasing incidence and unknown aetiology.
Aim: To identify possible environmental and hormonal factors related to FFA.
Methods: We conducted a multicentre case-control study paired by sex and age, and recruited 664 women (335 cases and 329 controls) and 106 men (20 cases and 86 controls). Read More
JAAD Case Rep 2018 Sep 22;4(8):848-850. Epub 2018 Sep 22.
Department of Dermatology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
BMC Ophthalmol 2018 Sep 14;18(Suppl 1):222. Epub 2018 Sep 14.
Western Eye Hospital, London, UK.
Background: The surgical management of patients with uncontrolled glaucoma and scleroderma is challenging, as the hostile ocular surface poses a challenge to surgery. A serious complication is tube erosion, with the risk of subsequent endophthalmitis. Here, we present a novel technique of harvesting autologous tissue to successfully manage recurrent tube extrusion. Read More
Ann Med Surg (Lond) 2018 Oct 12;34:58-61. Epub 2018 Sep 12.
Department for Plastic and Reconstructive Surgery, Canton Hospital Zenica, 72000 Zenica, Bosnia and Herzegovina.
Introduction: Eye lid reconstruction followed by severe, extensive body and facial burns represents a surgical challenge due to difficulties to obtain proper, healthy skin graft, tissue ischemia and necrosis.
Presentation Of Case: We present a reconstructive lid surgery of cicatricial bilateral lower eyelid ectropion in a case of 31-year-old man who sustained thermal injuries, affecting more than 60% of total body surface area, causing severe, deep dermal burns. Reconstruction was made using the technique of skin cantus-to-cantus incision, contracture release, orbicularis liberation and lid elevation; and oversizing free full-thickness skin graft (FTSG) (Wolfe technique) from the left inguinal region, as the only healthy skin on the entire body surface. Read More
Medicine (Baltimore) 2018 Sep;97(38):e12338
Department of Ophthalmology, The Affiliated Guangren Hospital of Xi'an Jiaotong University.
The application of methotrexate (MTX) in the treatment of autoimmune diseases has been gradually increasing, but reports of MTX treatment for advanced ocular cicatricial pemphigoid (OCP) are extremely rare. This study investigated the efficacy and adverse reactions of low-dose MTX in patients with OCP.This was a retrospective, noncontrolled, case series study. Read More
Am J Dermatopathol 2018 Oct;40(10):778-779
Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic.
Curr Opin Ophthalmol 2018 Nov;29(6):543-551
Francis I. Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, California, USA.
Purpose Of Review: This review offers recommendations for monitoring disease status in ocular cicatricial pemphigoid as well therapeutic options including local and systemic therapies.
Recent Findings: A negative biopsy on direct immunofluorescence does not preclude a diagnosis of OCP. If a patient's cicatrization is active and/or progressive, systemic immunosuppression should be commenced. Read More
Cureus 2018 Jul 6;10(7):e2936. Epub 2018 Jul 6.
Medical Imaging, CHU Jra, Antananarivo, MDG.
Objectives To determine the frequency of the demand of radiopelvimetry in pregnant women and to assess the obstetrical prognosis. Methods Retrospective study about 19 months, including a total of 45 pregnant women who underwent scanopelvimetry to evaluate the biometry of the pelvis. Scanopelvimetry was performed from 36th week of pregnancy. Read More
Skin Appendage Disord 2018 Aug 25;4(3):180-186. Epub 2017 Nov 25.
The Permanente Medical Group, Vallejo, CA.
Erosive pustular dermatosis (EPD) is a rare condition of the scalp and legs that is marked by crusted erosions or superficial ulcerations that may result in scarring alopecia and chronic wounds. The condition predominantly affects elderly female as compared to male patients. Its pathogenesis remains poorly understood. Read More
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Aug;43(8):843-851
Department of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
Objective: To evaluate the anti-cicatricial and anti-restenosis effect of verapamil on anterior urethral stricture. Methods: A total of 32 patients received anterior urethral stricture were enrolled in this study. They were divided into 4 blocks according to the duration of previous urethral operations and dilations. Read More
J Craniofac Surg 2018 Oct;29(7):1910-1911
Department of Ophthalmology.
Orbital implants are commonly used to repair orbital blowout fractures, to restore the functional and anatomical structure of the orbit. Porous polyethylene implants are a type of alloplastic implant and are widely used for orbital reconstruction as micropores facilitate the growth of fibers and blood vessels through the material. Rare complications associated with porous polyethylene implants used to treat blowout fractures include delayed orbital inflammation and osteomyelitis. Read More
Aesthetic Plast Surg 2018 Dec 6;42(6):1582-1590. Epub 2018 Sep 6.
Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, No. 33 Ba-Da-Chu Road, Shi-Jing-Shan District, Beijing, 100144, China.
Background: Incisional double-eyelid blepharoplasty is widely applied because of its extensive indications and robust results. The orbicularis-levator fixation method is an incisional approach that provides stronger adhesion than traditional techniques. However, there remains the risk of postoperative relapse or suture spitting out. Read More
J Dermatol 2018 Nov 6;45(11):1306-1311. Epub 2018 Sep 6.
Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
Primary cicatricial alopecia (PCA) is a dermatological challenge. Because no large-scale epidemiological study regarding PCA is available yet, we investigated the National Health Insurance Service-National Sample Cohort for patients diagnosed with PCA. The annual and overall rates of incidence and prevalence of PCA during the study period (2004-2013) were estimated. Read More
Dermatol Surg 2018 Aug 27. Epub 2018 Aug 27.
Heights Dermatology and Laser, Brooklyn, New York.
J Minim Access Surg 2018 Sep 3. Epub 2018 Sep 3.
Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
Background: Technological innovations have made it possible to use laparoscopic liver resection in cases with pre-existing adhesions or cicatricial changes. However, laparoscopic repeat liver resection (LRLR) still represents a challenge for surgeons, especially in case of previous open liver surgery. This study evaluated the outcomes of LRLR after open liver resection (OLR) in cases of recurrent liver cancer. Read More
Int J Womens Dermatol 2018 Sep 7;4(3):180-184. Epub 2018 Jun 7.
Department of Dermatology and Dermatopathology, Cleveland Clinic Foundation, Cleveland, Ohio.
Background: Lichen planopilaris (LPP) is a rare, cicatricial, lymphocyte-mediated alopecia that is thought to have an autoimmune pathogenesis and possibly related to other autoimmune diseases. However, data are limited and studies that examine comorbid conditions are lacking.
Objectives: We sought to determine the prevalence of systemic comorbid conditions, nutritional deficiencies, psychological problems, and skin cancers in patients with LPP. Read More
Am J Clin Dermatol 2018 Dec;19(6):893-897
Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgium.
Background: About 20% of children have cutaneous scars following chickenpox. In contrast, skin scars are not often reported after herpes zoster (HZ). Risk factors for post-HZ scarring remain undetermined. Read More
Dermatol Surg 2018 Aug 24. Epub 2018 Aug 24.
Meharry Medical College, Nashville, Tennessee Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Jul;32(7):951-954
Department of Burn and Plastic Surgery, the Affiliated Hospital of Zunyi Medical College, Zunyi Guizhou, 563003, P.R.China.
Objective: To investigate the effectiveness of modified free medial plantar flap with preserved abductor hallucis for repairing cicatricial contracture deformity of palm.
Methods: Between January 2012 and July 2017, a modified free medial plantar flap with preserved abductor hallucis was used to repair 9 cases of cicatricial contracture deformity at the palm. There were 7 males and 2 females with a median age of 23 years old (range, 15-40 years). Read More
J Mycol Med 2018 Dec 17;28(4):663-665. Epub 2018 Aug 17.
Departamento de Ecología de Agentes Patógenos, Hospital General Dr. Manuel Gea González, 14080 Tlalpan, Mexico. Electronic address:
Chromoblastomycosis is defined as a chronic cutaneous and subcutaneous fungal infection caused by melanized or brown-pigmented fungi. A 63-year-old man farmer showed on external and internal part of the right arm, a well-delimited verrucous and hyperkeratotic plaque, with atrophic and cicatricial areas. Direct examination of skin scrapings samples showed the presence of muriform cells, a classic feature of chromoblastomycosis. Read More
J Dtsch Dermatol Ges 2018 Aug;16(8):992-999
Department of Dermatology, Venereology and Allergology, University Medical Center, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.
Background: In his initial publication of frontal fibrosing alopecia (FFA) in 1994, Steven Kossard included six postmenopausal women. A type of cicatricial alopecia, FFA is clinically characterized by frontotemporal hairline recession and loss of eyebrows. In recent years, there has been an increasing number of case reports of FFA in both premenopausal women and men. Read More
JAAD Case Rep 2018 Aug 20;4(7):628-630. Epub 2018 Jul 20.
Moy-Fincher-Chipps, Encino, California.
Expert Opin Biol Ther 2018 Sep 9;18(9):997-1003. Epub 2018 Aug 9.
c Reproductive Medicine, Developmental Biology & Reproduction , University Hospital & School of Medicine, Picardie University Jules Verne , Amiens , France.
Introduction: Ocular surface diseases with limbal insufficiency represent a therapeutic challenge for restoring vision. This corneal deficiency includes both classical ocular diseases (as chemical burns) and rare ocular diseases (as congenital aniridia and ocular cicatricial pemphigoid). Areas covered: Our understanding of limbal epithelial stem cells (LESCs) has increased the potential for treatment options. Read More
Dermatology 2018 9;234(3-4):137-147. Epub 2018 Aug 9.
Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Background: Androgenetic alopecia (AGA) and alopecia areata (AA) are common causes of alopecia which can sometimes be difficult to differentiate clinically. Horizontal sections of scalp biopsies are used to study non-cicatricial alopecias due to the ability to perform both quantitative and morphometric analysis of hair follicles on them.
Methods: It was a prospective, cross-sectional study conducted to assess the utility of horizontal sections to differentiate between the alopecias. Read More