4,007 results match your criteria Chylothorax


A homozygous variant in growth and differentiation factor 2 (GDF2) may cause lymphatic dysplasia with hydrothorax and nonimmune hydrops fetalis.

Am J Med Genet A 2020 Jul 2. Epub 2020 Jul 2.

Department of Clinical Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

The etiology of nonimmune hydrops fetalis is extensive and includes genetic disorders. We describe a term-born female neonate with late onset extensive nonimmune hydrops, that is, polyhydramnios, edema, and congenital bilateral chylothorax. This newborn was successfully treated with repetitive thoracocentesis, total parenteral feeding, octreotide intravenously and finally surgical pleurodesis and corticosteroids. Read More

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http://dx.doi.org/10.1002/ajmg.a.61743DOI Listing

Chylothorax after Lung Cancer Surgery: A Key Factor Influencing Prognosis and Quality of Life.

Ann Thorac Cardiovasc Surg 2020 Jul 2. Epub 2020 Jul 2.

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Chylothorax is caused by the accumulation of chylous fluid in the pleural cavity due to the injury of the thoracic duct or its tributaries. Chylothorax following lung cancer surgery, especially pulmonary resection and mediastinal lymph node dissection, is a raw potential postoperative complication as previously reported. Chylothorax might lead to a high mortality rate if not addressed in a timely fashion. Read More

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http://dx.doi.org/10.5761/atcs.ra.20-00039DOI Listing

Lymphography and embolization of the thoracic duct as a treatment for chylothorax after esophagectomy for esophageal cancer.

Cir Esp 2020 Jun 26. Epub 2020 Jun 26.

Unitat de Cirurgia Esofagogàstrica, Servei de Cirurgia General i Aparell Digestiu, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, España.

Introduction: Chylothorax is a rare complication in esophagectomies that is associated with increased postoperative mortality. Several factors have been described that may favor its appearance. Its treatment is controversial, and lymphography with percutaneous embolization of the thoracic duct is used by several groups. Read More

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http://dx.doi.org/10.1016/j.ciresp.2020.05.015DOI Listing

Management of Complications After Esophagectomy.

Authors:
Jonathan C Yeung

Thorac Surg Clin 2020 Aug 22;30(3):359-366. Epub 2020 May 22.

Toronto General Hospital, 200 Elizabeth Street 9N-983, Toronto, Ontario M5G 2C4, Canada. Electronic address:

Esophagectomy is a complex operation with many potential complications. Early recognition of postoperative complications allows for the best chance for patient survival. Diagnosis and management of conduit complications, including leak, necrosis, and conduit-airway fistulae, are reviewed. Read More

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http://dx.doi.org/10.1016/j.thorsurg.2020.04.002DOI Listing

An Unusual Cause of Mediastinal Mass and Chylothorax.

Int J Appl Basic Med Res 2020 Apr-Jun;10(2):143-146. Epub 2020 Apr 2.

Department of Pulmonary Medicine, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.

Mediastinal masses are commonly encountered in clinical practice. The commonly encountered anterior mediastinal masses include those of thymic or thyroid origin, teratomas, and lymphoma. Establishing the diagnosis by histopathology is essential considering the wide range of differential diagnosis and to exclude malignancies. Read More

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http://dx.doi.org/10.4103/ijabmr.IJABMR_6_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289211PMC

Tuberculosis-associated chylothorax revealing an enlarged lymphatic duct due to tuberculosis lymphadenitis.

Respirol Case Rep 2020 Aug 18;8(6):e00600. Epub 2020 Jun 18.

Department of Respiratory Medicine Kyorin University School of Medicine Mitaka City Tokyo Japan.

A 77-year-old woman presented to our hospital with complaints of persistent cough and low-grade fever for two months. On radiological analysis, she had moderate right-sided pleural effusion with right hilar and subcarinal lymphadenopathies. Thoracentesis showed chylothorax of unknown cause. Read More

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http://dx.doi.org/10.1002/rcr2.600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301284PMC

Three-Field versus Two-Field Lymphadenectomy for Esophageal Squamous Cell Carcinoma: A Meta-Analysis.

J Surg Res 2020 Jun 18;255:195-204. Epub 2020 Jun 18.

Department of Orthopedics, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, China.

Background: Most surgeons now accept lymphadenectomy as an essential feature of the operative treatment of esophageal squamous cell carcinoma. Three-field and two-field lymphadenectomy are two of the most popular excision scopes among surgeons. Over recent years, researchers have performed a range of comparative studies regarding these techniques, although the conclusions remain inconsistent. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.057DOI Listing
June 2020
1.936 Impact Factor

Late diagnosis of generalized lymphangiomatosis in a woman presenting with respiratory distress.

Radiol Case Rep 2020 Aug 9;15(8):1189-1193. Epub 2020 Jun 9.

Student Research Committee, Sari Branch, Islamic Azad University, Sari, Iran.

Generalized lymphangiomatosis (GLA) is a rare lymphatic abnormality, mostly affects children and young individuals and can be a diagnostic challenge because of wide spectrum of clinical manifestations. A 26-year-old woman presented to the emergency department of our institution with respiratory distress and hypoxia. The patient reported similar episodes for the past 10 years without a definite diagnosis. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292890PMC

A Case of Congenital Lymphedema Complicated by Chronic Chylous Effusions and Recurrent Pericardial Effusion Requiring Pericardial Window.

Cureus 2020 May 16;12(5):e8160. Epub 2020 May 16.

Pulmonary Medicine, Joan C. Edwards School of Medicine, Marshall University, Huntington, USA.

We are presenting a case of primary lymphedema (PL) complicated with a repeated need for thoracentesis and pericardiocentesis. Our patient is a 24-year-old male with primary lymphedema that is manifested in the left hand and right lower limb. The patient presented to the emergency department (ED) for recurrent right lower lobe cellulitis that had failed repeated attempts with outpatient antibiotic therapy. Read More

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http://dx.doi.org/10.7759/cureus.8160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294872PMC

Application of Modified Sliding Anastomosis in the Repair of Aortic Coarctation.

Biomed Res Int 2020 14;2020:3805385. Epub 2020 May 14.

Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Middle Renmin Road 139, Changsha 410000, China.

Objectives: To evaluate the early and midterm results of a modified sliding anastomosis technique in patients with aortic coarctation.

Materials And Methods: In this study, we reported a new repair method and compared the early and midterm outcome(s) with a conventional surgical approach for the management of patients with aortic coarctation. Forty-eight aortic coarctation patients with a narrowed segment length longer than 2 cm were operated at our department's pediatric surgical division. Read More

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http://dx.doi.org/10.1155/2020/3805385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245663PMC

Tc-dextran Lymphoscintigraphy SPECT/CT unveil the hidden leakage site in recurrent chylothoraxes.

Ann Thorac Surg 2020 Jun 3. Epub 2020 Jun 3.

Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Hubei Province Key Laboratory of Molecular Imaging.

Chylothorax is defined as the accumulation of chyle in the pleural space, mainly by damaging to the thoracic duct. Tc-dextran, is a relatively new tracer for lymphoscintigraphy. A 40-year-old woman who had recurrent chylothoraxes after thymoma resection and ligation of the thoracic duct due to intraoperative suspected thoracic duct injury. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.068DOI Listing

Chylothorax Secondary to Dasatinib.

Arch Bronconeumol 2020 May 31. Epub 2020 May 31.

Servicio de Neumología, Hospital Universitario San Juan de Alicante, España. Electronic address:

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http://dx.doi.org/10.1016/j.arbres.2020.05.001DOI Listing

Treatment of Chylothorax after Lung Resection: Indications, Timing, and Outcomes.

Thorac Cardiovasc Surg 2020 Jun 3. Epub 2020 Jun 3.

Department of Thoracic Surgery, IRCCS European Institute of Oncology, Milan, Lombardia, Italy.

Background:  Chylothorax following pulmonary resection and lymphadenectomy for cancer is a potential severe complication in thoracic surgery. In the present study, we investigated the efficacy of the nonsurgical approach as well as the need for reoperation after conservative approach failure.

Methods:  Chylothorax was diagnosed when chylous leakage from the chest drainage was observed and confirmed by the presence of triglycerides in the pleural fluid. Read More

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http://dx.doi.org/10.1055/s-0040-1710071DOI Listing

Chylothorax caused by blunt trauma: Case review and management proposal.

Trauma Case Rep 2020 Aug 21;28:100308. Epub 2020 May 21.

Department of Surgery, St. Luke's Hospital of Kansas City, MO, United States of America.

Chylothorax is a potentially devastating complication of lymphatic trauma of the thorax. To date, no recommendations have provided decision making support for prompt definitive treatment. We present a 53 year old male involved in a motor vehicle collision sustaining 9 left rib fractures with flail segments. Read More

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http://dx.doi.org/10.1016/j.tcr.2020.100308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256325PMC

Title of the manuscript: Chylothorax in a 4-year-old boy with trisomy 21.

Pediatr Pulmonol 2020 Jun 1. Epub 2020 Jun 1.

Pediatric Infectious Disease Department, Hospital Universitario La Paz, Madrid, Spain.

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http://dx.doi.org/10.1002/ppul.24868DOI Listing

Refractory chylous effusions in lymphangioleiomyomatosis patient post lung transplant.

SAGE Open Med Case Rep 2020 6;8:2050313X20921332. Epub 2020 May 6.

Department of Transplantation, Mayo Clinic, Jacksonville, FL, USA.

Lymphangioleiomyomatosis is a rare systemic disorder of unknown etiology that affects young women almost exclusively. Chylous effusions are known to be associated with lymphangioleiomyomatosis and may be difficult to treat. We present the case of a 37-year-old female who received bilateral lung transplantation for lymphangioleiomyomatosis complicated by refractory chylothorax and chylous ascites, ultimately controlled through repeated, open surgical procedures and percutaneous lymphatic embolization interventions. Read More

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http://dx.doi.org/10.1177/2050313X20921332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233883PMC

[Postoperative Chylothorax Likely to be Successfully Treated by Lymphangiography;Report of a Case].

Kyobu Geka 2020 Jun;73(6):462-465

Department of General Thoracic Surgery, Kochi Health Sciences Center, Kochi, Japan.

A 74-year-old man underwent right upper lobectomy and systemic lymph node dissection with video-assisted thoracoscopic surgery. Chylothorax occurred on postoperative day (POD) 1st. Under fasting management, the patient underwent pleurodesis on POD 5th and 7th, subcutaneous octreotide acetate injection on POD 6th, and lymphangiography on POD 9th. Read More

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Lipoprotein Lipase Deficiency.

Indian J Pediatr 2020 May 30. Epub 2020 May 30.

Department of Pediatric Genetics, Amrita Institute of Medical Sciences & Research Centre, Aims Ponekkara PO, Cochin, Kerala, 682041, India.

Objectives: To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder.

Methods: This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more than 1000 mg/dl) were evaluated for a period of 12. Read More

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http://dx.doi.org/10.1007/s12098-020-03305-zDOI Listing

Magnetic Resonance Lymphangiography.

Radiol Clin North Am 2020 Jul 6;58(4):693-706. Epub 2020 May 6.

Department of Diagnostic Imaging, The Hospital for Sick Children and Medical Imaging, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada; Division of Cardiology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.

Dynamic contrast-enhanced magnetic resonance lymphangiography is a novel technique to image central conducting lymphatics. It is performed by injecting contrast into groin lymph nodes and following passage of contrast through lymphatic system using T1-weighted MR images. Currently, it has been successfully applied to image and plan treatment of thoracic duct pathologies, lymphatic leaks, and other lymphatic abnormalities such as plastic bronchitis. Read More

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http://dx.doi.org/10.1016/j.rcl.2020.02.002DOI Listing

Thoracic duct identification with indocyanine green fluorescence during minimally invasive esophagectomy with patient in prone position.

Dis Esophagus 2020 May 25. Epub 2020 May 25.

Division of Surgery, Department of Surgery, ASUI "Santa Maria della Misericordia", Udine, Italy.

Chylothorax is a serious complication of transthoracic esophagectomy. Intraoperative thoracic duct (TD) identification represents a possible tool for preventing or repairing its lesions, and it is most of the time difficult, even during high-definition thoracoscopy. The aim of the study is to demonstrate the feasibility of using near-infrared fluorescence-guided thoracoscopy to identify TD anatomy and check its intraoperative lesions during minimally invasive esophagectomy. Read More

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http://dx.doi.org/10.1093/dote/doaa030DOI Listing

Refractory chylothorax and chylous ascites as form of presentation of diffuse lymphangiomatosis.

Med Clin (Barc) 2020 May 20. Epub 2020 May 20.

Servicio de Urgencias, Hospital Universitario Virgen de las Nieves, Granada, España.

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http://dx.doi.org/10.1016/j.medcli.2020.03.007DOI Listing

Congenital Chylothorax with Lymphatic Malformation and Successful Antenatal and Postnatal Management.

Indian Pediatr 2020 May;57(5):470-472

Department of Neonatology, Fortis Memorial Research Institute, Gurgaon, India.

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Chylothorax in a Case of Accelerated Silicosis with Pulmonary Silicoproteinosis: A Unique Association.

Indian J Occup Environ Med 2020 Jan-Apr;24(1):39-41. Epub 2020 Mar 18.

Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.

A 32-year-old gentleman, a worker in a cement-manufacturing facility with suspected silica-induced lung disease presented with acutely worsening Type 1 respiratory failure. With a negative work-up for infectious causes and no further revelations on bronchoalveolar lavage fluid or endobronchial biopsy, it was a transbronchial biopsy that ultimately led us to a diagnosis of silicoproteinosis with accelerated silicosis. Interestingly, the patient had a pleural effusion which on thoracentesis showed chylous fluid-the first reported case of chylothorax in association with silicosis. Read More

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http://dx.doi.org/10.4103/ijoem.IJOEM_63_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227742PMC

Povidone-iodine chemical pleurodesis in treating spontaneous chylothorax in pediatric patients.

Ann Palliat Med 2020 May 11;9(3):1004-1012. Epub 2020 May 11.

Department of Chest Wall Surgery, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.

Background: Chylothorax is a rare disease with a high mortality rate in pediatric patients like newborns and infants. As one of the minimally invasive treatments, chemical pleural pleurodesis has been gradually used in treating pediatric chylothorax patients in recent years. This study explored the feasibility, safety and effect of povidone-iodine chemical pleurodesis (CP) for spontaneous chylothorax in young pediatric patients. Read More

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http://dx.doi.org/10.21037/apm-20-926DOI Listing

Thoracoscopic Vertebral Body Tethering for Adolescent Idiopathic Scoliosis: A Minimum of 2 Years' Results of 21 Patients.

J Pediatr Orthop 2020 May 15. Epub 2020 May 15.

Departments of Orthopaedic Surgery and Traumatology.

Background: Anterior vertebral body tethering (VBT) is a growth modulating and fusionless treatment option that is considered as a new promising method for the management of adolescent idiopathic scoliosis (AIS). This prospective cohort study aimed to present the minimum 2-year results of anterior VBT applied to 21 skeletally immature patients with AIS.

Methods: Twenty-one skeletally immature patients with a diagnosis of AIS were included. Read More

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http://dx.doi.org/10.1097/BPO.0000000000001590DOI Listing

Combined antegrade and retrograde thoracic duct embolization for complete transection of the thoracic duct.

Radiol Case Rep 2020 Jul 7;15(7):929-932. Epub 2020 May 7.

Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA.

Chylothorax is an uncommon complication after thoracoabdominal surgery and is typically due to injury of the thoracic duct (TD) or one of its tributaries. Patients who fail conservative management benefit from thoracic duct embolization (TDE). TDE is a percutaneous technique that includes pedal or intranodal lymphangiography, transabdominal catheterization of the TD, and glue embolization of the TD. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215112PMC

[Surgical Treatment for Postoperative Chylothorax after Aortic Arch Replacement via Median Sternotomy].

Kyobu Geka 2020 Mar;73(3):197-201

Department of Cardiovascular Surgery, Kawaguchi Cardiovascular and Respiratory Hospital, Kawaguchi, Japan.

Postoperative chylothorax is known as a possible complication after thoracic surgery, but no treatment strategy has been established. We report a case of successful surgical treatment for postoperative chylothorax after redo aortic arch replacement via median sternotomy. A 48-year-old man, who had undergone redo aortic arch replacement for aortic pseudoaneurysm due to prosthetic vascular graft infection, developed postoperative chylothorax. Read More

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Postoperative chylothorax with a duplicated left-sided thoracic duct: a case report and review of the literature.

Gen Thorac Cardiovasc Surg 2020 May 8. Epub 2020 May 8.

Division of Esophageal Surgery, Shizuoka Cancer Center, 1007, Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan.

Postoperative chylothorax is a potentially lethal complication after esophagectomy. A 53-year-old woman underwent subtotal esophagectomy. The thoracic duct was resected due to swollen lymph nodes. Read More

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http://dx.doi.org/10.1007/s11748-020-01374-7DOI Listing

Chylothorax as an Initial Manifestation of Waldenström macroglobulinemia.

Cureus 2020 Apr 6;12(4):e7566. Epub 2020 Apr 6.

Internal Medicine, Hospital Pablo Tobon Uribe, Medellín, COL.

Waldenström macroglobulinemia (WM) is an uncommon disease whose most common presenting features are anemia, hyperviscosity-related symptoms, B symptoms, bleeding, and neurological symptoms. Pulmonary compromise is rare, and there are a few cases reported of chylothorax as a manifestation of Waldenström macroglobulinemia. We present the case of a patient who presented with a refractory chylothorax as the initial manifestation of Waldenström macroglobulinemia. Read More

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http://dx.doi.org/10.7759/cureus.7566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202585PMC

Quantification of Thoracic Lymphatic Flow Patterns Using Dynamic Contrast-enhanced MR Lymphangiography.

Radiology 2020 Jul 5;296(1):202-207. Epub 2020 May 5.

From the School of Computer and Control Engineering, Yantai University, Yantai, China (Q.Z.); Department of Radiology (M.I., Y.F.) and Center for Lymphatic Disorders (M.I.), Perelman School of Medicine, University of Pennsylvania, 3700 Hamilton Walk, Richards Building, 7th Floor, Room D703, Philadelphia, PA 19104.

Background Dynamic contrast material-enhanced MR lymphangiography has recently emerged as a technique to image the lymphatic anatomy and identify lymphatic flow abnormalities; however, a method to quantify lymphatic flow in health and disease is needed. Purpose To develop a method to quantify thoracic lymphatic flow patterns using dynamic contrast-enhanced MR lymphangiography. Materials and Methods The following patients with dynamic contrast-enhanced MR lymphangiography images collected in 2015 and 2016 were retrospectively identified: group A, neonates with chylothorax; group B, children with heart failure complicated by plastic bronchitis; and group C, adults with lymphatic plastic bronchitis and without heart failure. Read More

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http://dx.doi.org/10.1148/radiol.2020192337DOI Listing

Computed tomographic lymphangiography via intra-metatarsal pad injection is feasible in dogs with chylothorax.

Vet Radiol Ultrasound 2020 May 3. Epub 2020 May 3.

Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, Taiwan.

Lymphangiography can be useful for preoperative planning in chylothorax. Conventional ultrasound-guided intranodal injection can be difficult in some cases and is dependent upon operator skill. Alternative methods have been proposed to simplify the procedure, but their feasibility has not been sufficiently evaluated in clinical cases. Read More

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http://dx.doi.org/10.1111/vru.12865DOI Listing

Lymphatic Management in Single-Ventricle Patients.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020 ;23:41-47

Neours/Dupont Children's Hospital, Wilmington, Delaware.

Lymphatic complications in patients with single ventricle include plastic bronchitis, protein-losing enteropathy, and chylous pleural effusion are a source of significant morbidity and mortality with historically limited therapeutic options. Novel lymphatic imaging techniques such as intranodal lymphangiography, dynamic contrast enhanced magnetic resonance lymphangiography and liver lymphangiography have allowed visualization of the lymphatic system and discovery of the pathophysiological mechanism of these conditions. This mechanism includes the combination of 2 factors: increased lymphatic flow in patients with elevated central venous pressure and presence of the lymphatic anatomical variant that allows the lymph to flow in close proximity to the serous (pleural space in chylothorax) or mucosal (plastic bronchitis and protein losing enteropathy) surfaces. Read More

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http://dx.doi.org/10.1053/j.pcsu.2020.03.001DOI Listing
January 2020

Innominate Vein Turn-down Procedure for Failing Fontan Circulation.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2020 ;23:34-40

Division of Pediatric Cardiology, Department of Pediatrics, Herma Heart Institute, Medical College of Wisconsin, Milwaukee, Wisconsin.

After the Fontan, systemic venous hypertension induces pathophysiologic changes in the lymphatic system that can result in complications of pleural effusion, ascites, plastic bronchitis, and protein losing enteropathy. Advances in medical therapy and novel interventional approaches have not substantially improved the poor prognosis of these complications. A more physiological approach has been developed by decompression of the thoracic duct to the lower pressure common atrium with a concomitant increase of preload. Read More

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http://dx.doi.org/10.1053/j.pcsu.2020.01.002DOI Listing
January 2020

Gefitinib as neoadjuvant therapy for resectable stage II-IIIA non-small cell lung cancer: A phase II study.

J Thorac Cardiovasc Surg 2020 Mar 19. Epub 2020 Mar 19.

Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Institute of Thoracic Oncology, Fudan University, Shanghai, China; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:

Introduction: Currently, limited data on tyrosine kinase inhibitors as neoadjuvant therapy exist. This prospective study aimed to investigate the efficacy and safety of preoperative gefitinib in patients with stage II-IIIA operable non-small cell lung cancer (NSCLC).

Methods: This was a single-arm, phase II trial performed in the Shanghai Cancer Center. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2020.02.131DOI Listing
March 2020
4.168 Impact Factor

[A clinical analysis of neonatal chylous effusions].

Zhongguo Dang Dai Er Ke Za Zhi 2020 Apr;22(4):328-333

Department of Pediatrics, Peking University Third Hospital, Beijing 100191, China.

Objective: To study the clinical features, etiology, treatment, and prognosis of neonatal chylous effusions.

Methods: A retrospective analysis was performed for the clinical data of 21 neonates with chylous effusions.

Results: Among these 21 neonates, 13 had chylothorax, 2 had chyloperitoneum, 2 had chylopericardium, and 4 had chylous polyserositis. Read More

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Utility of planning MRI in percutaneous thoracic duct embolization for chylothorax.

Clin Imaging 2020 Aug 5;64:43-49. Epub 2020 Apr 5.

Harvard Medical School, Brigham and Women's Hospital, Department of Radiology, Division of Angiography and Interventional Radiology, Midcampus SR-340, 75 Francis Street, Boston, MA 02115, United States of America.

Purpose: Percutaneous thoracic duct embolization (TDE) is an accepted treatment for leaks of the central lymphatic ducts. In this study, we correlate the imaging findings on pre-procedural MRI lymphangiography with findings on conventional lymphangiography, and with operator ability to perform a technically successful TDE. The aim was to examine whether MRI is a good screening mechanism to support an invasive procedure in strong candidates, and avert one in poor candidates. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.03.014DOI Listing

Corrigendum: Lymphangiographic Interventions to Manage Postoperative Chylothorax.

Korean J Thorac Cardiovasc Surg 2020 Apr;53(2):92

Department of Internal Medicine, Pusan National University Hospital, Pusan National University Medical Research Institution, Busan, Korea.

[This corrects the article on p. 409 in vol. 52, PMID: 31832377. Read More

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http://dx.doi.org/10.5090/kjtcs.2020.53.2.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155183PMC

Chylothorax after Surgery for Congenital Cardiac Disease: A Prevention and Management Protocol.

Korean J Thorac Cardiovasc Surg 2020 Apr;53(2):41-48

Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: Chylothorax after congenital heart surgery is not an uncommon complication, and it is associated with significant morbidity. However, consensus treatment guidelines are lacking. To improve the treatment outcomes of patients with postoperative chylothorax, we implemented a standardized management protocol at Severance Hospital in September 2014. Read More

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http://dx.doi.org/10.5090/kjtcs.2020.53.2.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155178PMC

Lymphatic Decompression Concomitant With Fontan/Kreutzer Procedure: Early Experience.

World J Pediatr Congenit Heart Surg 2020 May;11(3):284-292

Division of Pediatric Critical Care, Hospital Universitario Austral, Pilar, Buenos Aires, Argentina.

Objective: To present a strategy for identifying patients at risk of lymphatic failure in the setting of planned Fontan/Kreutzer completion, allowing a tailored surgical approach.

Methods: Since January 2017, clinical evaluation before performance of the Fontan/Kreutzer procedure included T2-weighted magnetic resonance imaging (MRI) lymphangiography. Thoracic lymphatic abnormalities were categorized using a scale of I to IV according to progression of severity. Read More

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http://dx.doi.org/10.1177/2150135120905656DOI Listing

Transjugular intrahepatic portosystemic shunt for a patient with chylothorax in cryptogenic/metabolic cirrhosis.

Hepatobiliary Pancreat Dis Int 2020 Jun 20;19(3):303-304. Epub 2020 Mar 20.

Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.hbpd.2020.03.008DOI Listing

Fontan completion during winter season is not associated with higher mortality or morbidity in the early post-operative period.

Cardiol Young 2020 May 13;30(5):629-632. Epub 2020 Apr 13.

German Heart Center Berlin, Department of Congenital Heart Disease - Pediatric Cardiology, Berlin, Germany.

Objectives: The aim of our study was to compare post-operative outcome after total cavopulmonary connection between patients operated during winter and summer season.

Methods: We retrospectively studied 211 patients who underwent extracardiac total cavopulmonary connection completion at our institution between 1995 and 2015 (median age 4 (1-42) years). Seventy (33%) patients were operated during winter (November to March) and 141 (67%) patients during summer season (April to October). Read More

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http://dx.doi.org/10.1017/S1047951120000670DOI Listing

Application of imaging technique in thoracic duct anatomy.

Ann Palliat Med 2020 May 31;9(3):1249-1256. Epub 2020 Mar 31.

Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou 350122, China.

The thoracic duct is an important anatomical structure of the abdomen, chest and neck. An accurate understanding of the anatomy of the thoracic duct is critical to ensuring the safety and accuracy of the surgical procedure involving these areas, which can help surgeons reduce accidental injuries and provide more accurate diagnosis and intervention for patients with serious complications such as chylothorax, etc. In addition, it has great reference value to know the anatomy of thoracic duct in advance for the selection of treatment strategies in the treatment of refractory pleural effusion and ascites, chylothorax, and heart failure. Read More

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http://dx.doi.org/10.21037/apm.2020.03.10DOI Listing

Comparison of outcomes after differentiated thyroid cancer surgery performed with and without energy devices: A population-based cohort study using a nationwide database in Japan.

Int J Surg 2020 May 9;77:198-204. Epub 2020 Apr 9.

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Japan.

Background: The benefits of using energy devices (EDs) such as ultrasonic coagulating shears or electrothermal bipolar vessel sealing devices for thyroid cancer surgery have been evaluated only with limited data obtained from small samples.

Materials And Methods: Using a Japanese national inpatient database, we identified 59,394 patients with thyroid cancer who underwent thyroidectomy without EDs (without-ED group, n = 32,360) and with EDs (with-ED group, n = 26,764) from July 2010 to March 2017. One-to-one propensity score matching was performed to compare the occurrence of postoperative complications including recurrent laryngeal nerve paralysis and chyle leakage, duration of anesthesia, length of stay, total costs, in-hospital mortality rate between the two groups. Read More

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http://dx.doi.org/10.1016/j.ijsu.2020.03.072DOI Listing

Simplified method to quantify valve back-leak uncovers severe mesenteric lymphatic valve dysfunction in mice deficient in connexins 43 and 37.

J Physiol 2020 Jun 10;598(12):2297-2310. Epub 2020 May 10.

Department of Medical Pharmacology and Physiology, School of Medicine, University of Missouri, Columbia, MO, USA.

Key Points: Lymphatic valve defects are one of the major causes of lymph transport dysfunction; however, there are no accessible methods for quantitatively assessing valve function. This report describes a novel technique for quantifying lymphatic valve back-leak. Postnatal endothelial-specific deletion of connexin 43 (Cx43) in connexin 37 null (Cx37 ) mice results in rapid regression of valve leaflets and severe valve dysfunction. Read More

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http://dx.doi.org/10.1113/JP279472DOI Listing

Postoperative complications of minimally invasive esophagectomy for esophageal cancer.

Ann Gastroenterol Surg 2020 Mar 12;4(2):126-134. Epub 2020 Feb 12.

Department of Gastroenterological Surgery Tokai University School of Medicine Kanagawa Japan.

Minimally invasive esophagectomy (MIE) has been performed increasingly more frequently for the treatment of esophageal cancer, ever since it was first described in 1992. However, the incidence of postoperative complications of MIE has not yet been well-characterized, because (a) there are few reports of studies with a sufficient sample size, (b) a variety of minimally invasive surgical techniques are used, and (c) there are few reports in which an established system for classifying the severity of complications is examined. According to an analysis performed by the Esophageal Complications Consensus Group, the most common complications of MIE are pneumonia, arrhythmia, anastomotic leakage, conduit necrosis, chylothorax, and recurrent laryngeal nerve palsy. Read More

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http://dx.doi.org/10.1002/ags3.12315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105848PMC

A 34-Year-Old Man With a Chylothorax and Bony Pain.

Chest 2020 Apr;157(4):e131-e136

Department of Respiratory Medicine, St. Vincent's University Hospital, Dublin, Ireland; Department of Medicine, University College Dublin, Dublin, Ireland. Electronic address:

Case Presentation: A 34-year-old man presented to a community hospital with sudden-onset pleuritic chest pain on a background of a 12-month indolent history of progressive exertional dyspnea. He denied cough, fevers, night sweats, or weight loss. He reported some low back pain and ache. Read More

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http://dx.doi.org/10.1016/j.chest.2019.10.033DOI Listing

Dasatinib-induced chylothorax: report of a case and review of the literature.

Invest New Drugs 2020 Apr 4. Epub 2020 Apr 4.

Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, Sichuan, China.

Dasatinib is a tyrosine kinase inhibitor for the treatment of BCR-ABL-positive chronic myeloid leukaemia (CML) or Philadelphia chromosome-positive acute lymphoblastic leukaemia (ALL). Although fluid retention is a common adverse event associated with dasatinib, chylothorax is exceptionally rare. The pathological mechanism, clinical manifestation and management of dasatinib-induced chylothorax are completely unclear. Read More

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http://dx.doi.org/10.1007/s10637-020-00932-3DOI Listing

Chylous Leak During Posterior Approach to Juvenile Scoliosis Surgery: A Case Report.

JBJS Case Connect 2020 Jan-Mar;10(1):e0100

Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, California.

Case: We report the first documented case of chylous leak recognized intraoperatively during posterior spinal instrumentation and fusion for juvenile scoliosis in a female patient with a history of thoracotomy and decortication for an empyema.

Conclusions: Thoracic duct injury can lead to severe morbidity and mortality because of chylothorax formation. Although chylous leaks are a well-documented complication of the anterior approach to spine surgery, leaks during the posterior approach are rarely reported. Read More

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http://dx.doi.org/10.2106/JBJS.CC.19.00100DOI Listing

Direct-Puncture Lymphatic Embolization in the Prone Position for Chylothorax Caused by Lymphatic Anomaly.

J Vasc Interv Radiol 2020 May 26;31(5):849-852.e1. Epub 2020 Mar 26.

Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.

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http://dx.doi.org/10.1016/j.jvir.2019.11.011DOI Listing

Prevalence and Cause of Early Fontan Complications: Does the Lymphatic Circulation Play a Role?

J Am Heart Assoc 2020 Apr 30;9(7):e015318. Epub 2020 Mar 30.

Division of Cardiology Children's Hospital of Philadelphia PA.

Background Recent studies suggest that lymphatic congestion plays a role in development of late Fontan complications, such as protein-losing enteropathy. However, the role of the lymphatic circulation in early post-Fontan outcomes is not well defined. Methods and Results This was a retrospective, single-center study of patients undergoing first-time Fontan completion from 2012 to 2017. Read More

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http://dx.doi.org/10.1161/JAHA.119.015318DOI Listing