Search Our Scientific Publications & Authors

Phlebology 2020 Aug 2:268355520947292. Epub 2020 Aug 2.

Department of Cardiology, Bezmialem Vakif University, Istanbul, Turkey.

Objectives: To compare traditional surgery with two minimally invasive endo-venous procedures in terms of their long-term effect on the quality of life in great saphenous vein insufficiency (GSV).

Method: This prospective observational study included 217 patients that underwent surgical stripping (n = 62), radiofrequency ablation (n = 70), or cyanoacrylate embolization (n = 85) for the treatment of GSV insufficiency. Venous Clinical Severity Score (VCSS) assessments were made, 36-item Short-Form Health Survey (SF-36) questionnaire and Chronic Venous Insufficiency quality of life Questionnaire (CIVIQ-14) were administered, before and 1 year after the treatments. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jul 27. Epub 2020 Jul 27.

University of California, Davis, Vascular Center, Sacramento, CA USA. Electronic address:

Objective: Our goal was to summarize the relationship between vein diameters, reflux characteristics, and clinical severity in consecutive patients with chronic venous insufficiency in Northwest China.

Methods: We evaluated 531 consecutive patients with chronic venous insufficiency (249 women) who presented to the Department of Ultrasound of Xijing Hospital from September 2017 to July 2019. Reflux times and the mean diameters of the great saphenous, the small saphenous, and the calf perforator veins based on duplex ultrasound scans obtained in the standing position were recorded. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jul 25. Epub 2020 Jul 25.

Section of Vascular Surgery, Department of Surgery, University of Michigan Health System; Department of Vascular Surgery, Jobst Vascular Institute, Promedica, Toledo, OH. Electronic address:

Objective: Intersocietal Accreditation Commission (IAC) of vein centers was instituted in 2014, yet data regarding impact of accreditation on patients undergoing superficial venous interventions was lacking. This study was undertaken to identify differences in patient outcomes and utilization index as a measure of appropriate use in accredited compared to non-accredited centers.

Methods: This study was performed with a match control design utilizing prospectively collected data from two major US-based venous registries: Society for Vascular Surgery Varicose Vein Registry (VQI VVR), and the American College of Phlebology (AVLS PROVein). Read More

Hautarzt 2020 Jul 27. Epub 2020 Jul 27.

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Deutschland.

A 59-year-old obese woman had been suffering from a painful, chronic leg ulcer since 1986. We diagnosed a venous leg ulcer due to functional chronic venous insufficiency in the context of obesity per magna (dependency syndrome) and arthrogenic congestion syndrome due to immobility. Although a high ligation and stripping of the great saphenous vein and several so-called shave therapies with split skin transplantation after appropriate wound bed preparation had been previously performed, the wound persisted. Read More

Phlebology 2020 07 26:268355520941359. Epub 2020 Jul 26.

Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Switzerland.

Skin hyperpigmentation in chronic venous insufficiency and as a side effect in vein treatments are of great importance for the affected individuals. There are only a few qualitatively limited methods that allow its quantification. Previous techniques to develop a reliable scientific approach to quantification have failed due to the lack of standardized conditions including differences in lighting, distances and equipment. Read More

Clin Appl Thromb Hemost 2020 Jan-Dec;26:1076029620943671

Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Severe acute respiratory syndrome coronavirus 2 infection (COVID-19) is known to induce severe inflammation and activation of the coagulation system, resulting in a prothrombotic state. Although inflammatory conditions and organ-specific diseases have been shown to be strong determinants of morbidity and mortality in patients with COVID-19, it is unclear whether preexisting differences in coagulation impact the severity of COVID-19. African Americans have higher rates of COVID-19 infection and disease-related morbidity and mortality. Read More

Medicine (Baltimore) 2020 Jul;99(29):e20954

aDepartment of Orthopedics, Qilu Hospital of Shandong University and Spine and Spinal Cord Disease Research Center, Shandong University bDepartment of Medical Oncology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Background: To investigate the risk factors for postoperative venous thromboembolism (VTE) in patients undergoing spinal surgery.

Methods: Literature published in PubMed, Embase, the Cochrane Library, and Web of Science was systematically reviewed to assess risk factors for VTE following spinal surgery. The data analysis was conducted with STATA 12. Read More

Rev Bras Med Trab 2019 1;17(4):589-593. Epub 2019 Dec 1.

Ribeirão Preto School of Medicine, Master's in Health Organization Management - Ribeirão Preto (SP), Brazil. Ribeirão Preto School of Medicine Master's in Health Organization Management Brazil.

The aim of the present study was to perform a literature review about the symptoms, treatment and prevention of varicose veins (VV) within the occupational medicine setting. I reviewed scientific articles, books, master's and doctoral dissertations and synthesized the results of quantitative and qualitative studies. I further retrieved information from Brazilian federal government occupational health websites. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jul 15. Epub 2020 Jul 15.

Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, Spain; Department of Medicine, School of Medicine, Universidad Complutense, Madrid, Spain. Electronic address:

Objective: The objective of this study was to analyze whether compression stocking therapy in the human varicose vein wall may change the levels of biomarkers associated with vein insufficiency.

Methods: Dilated collateral varicose vein samples were obtained from patients showing chronic venous disease (class 2 of the Clinical, Etiology, Anatomy, and Pathophysiology classification). Before elective surgery, 12 patients underwent compression stocking therapy (for 1 month) and 9 patients did not (control group). Read More

Radiol Case Rep 2020 Sep 4;15(9):1518-1522. Epub 2020 Jul 4.

Department of Radiology, Hospital del Mar, Passeig Marítim de la Barceloneta, 25, 29, 08003, Barcelona, Spain.

Venous insufficiency is a frequent cause of consultation in primary care settings. Heterotopic ossification, consisting of an abnormal formation of true bone in extraskeletal soft tissues, is an underrecognized complication of chronic venous insufficiency that may cause torpid ulcers. We report a case of 78-year-old woman, with a long-standing history of venous insufficiency and tibial fracture, showing a non-healing ulcer associated with subcutaneous calcifications of the left lower extremity. Read More

Phlebology 2020 Jul 14:268355520940921. Epub 2020 Jul 14.

Faculty of Medicine, Department of Neurology, Bursa Uludağ University, Bursa, Turkey.

Background: We aimed to investigate of chronic venous insufficiency on patients with sleep disorder due to restless legs syndrome.

Method: Five hundred forty-one cases on whom polysomnography was performed due to sleep disorder were evaluated retrospectively. Forty patients with restless legs syndrome were determined. Read More

Eplasty 2020 5;20:e6. Epub 2020 Jun 5.

Center for Curative and Palliative Wound Care, Calvary Hospital, Bronx, NY.

Fifty-two subjects with chronic venous insufficiency and hard-to-heal lower leg ulceration (>1-year-old and >20-cm surface area) were treated with either intermittent, gradient, pneumatic compression (n = 27) plus standard compression therapy or compression therapy alone (control). Compression therapy consisted of a nonadherent primary wound dressing plus a 4-layer compression bandage (n = 25). The mean age and size of the ulcers were 1. Read More

Phlebology 2020 Jul 6:268355520937619. Epub 2020 Jul 6.

Department of Surgery, NYU Langone Health, New York City, NY, USA.

Objective: To provide an evidence-based overview of endovenous laser ablation and describe its role as an effective and durable technique for the management of superficial venous insufficiency.

Methods: The published literature on the treatment of varicose veins using endovenous laser ablation was reviewed. The literature search focused on the history of endovenous laser ablation, its safety and durability, known complications, and differences in outcomes based on the iterations of fiber type and laser wavelength. Read More

Medicine (Baltimore) 2020 Jul;99(27):e20843

Department of Emergency, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.

Rationale: Extubation strategy for mechanically ventilated patients with Coronavirus Disease 19 is different from that for patients with other viral pneumonia. We reported 2 cases of Coronavirus Disease 19 receiving tracheal intubation twice during the hospitalization.

Patient Concerns: Two elderly patients with onset of fever and upper respiratory tract infection were confirmed as Coronavirus Disease 19, 1 of whom had chronic obstructive pulmonary disease previously. Read More

Sleep Med 2020 Apr 10;72:135-137. Epub 2020 Apr 10.

Association des Médecins Vasculaires Hospitaliers, Service de Médecine Vasculaire CHU Montpellier, France.

Background: Obstructive sleep apnea (OSA) is highly prevalent in conditions characterized by fluid overload. Chronic venous insufficiency (CVI) is associated to fluid overload that might interfere with OSA occurrence and severity.

Methods: A total of 180 patients with symptomatic CVI completed the Berlin questionnaire and were assessed for the presence of symptoms and signs of OSA and fluid shift. Read More

SAGE Open Med Case Rep 2020 22;8:2050313X20936078. Epub 2020 Jun 22.

Department of Nephropathy, The First Hospital of Jilin University, Changchun, China.

Varicose ulcer, a severe symptom of chronic venous insufficiency, may be refractory to treatment when accompanied by bone exposure. The lack of a blood supply and fresh granulation tissue on the exposed bone can result in a protracted healing time. A 59-year-old man suffered from varicose veins for 10 years, a varicose ulcer for 1 year, and an exposed right tibia for 40 days after using traditional Chinese medicinal plasters. Read More

Vasc Specialist Int 2020 Jun;36(2):116-121

Departments of Surgery, Seoul National University College of Medicine, Seoul, Korea.

Inferior vena cava filters (IVCFs) are effective in preventing pulmonary embolism and their usage has rapidly increased over the past decades. However, complications have also significantly increased, as IVCF occlusion causes serious chronic venous insufficiency. Herein, we report a case of infrarenal IVCF occlusion that was successfully treated with the introduction of kissing stents through the IVCF into both iliac veins. Read More

Ann Vasc Surg 2020 Jun 27. Epub 2020 Jun 27.

Division of Vascular Surgery, University of Pittsburgh, Pittsburgh, PA.

Background: Venous leg ulceration (VLU) represents the most advanced form of chronic venous insufficiency (CVI). Persistent VLU that fails to respond to noninvasive treatment requires a minimally invasive endovascular treatment, which may include chemical (ultrasound-guided foam sclerotherapy [UGFS]) and thermal ablation (endovenous laser therapy [EVLT] or radiofrequency ablation [RFA]) targeting incompetent veins. Current guidelines suggest ablation of incompetent perforating veins (IPVs) juxtaposed to active or healed VLU; however, the ideal treatment modality is unknown. Read More

Angiol Sosud Khir 2020 ;26(2):95-102

Limited Liability Company 'Expert Legal Centre', Moscow, Russia.

Aim: The purpose of this study was to prove that Detravenol is not inferior by clinical efficacy to Detralex® in the course administration in patients presenting with chronic venous insufficiency of the lower extremities caused by lower limb varicose veins.

Patients And Methods: Ours was a prospective randomized open-liable comparative trial aimed at determining efficacy and safety of the two drugs in parallel groups with active control. The trial enrolled a total of 106 patients with chronic venous insufficiency of the lower extremities secondary to lower limb varicose veins. Read More

Angiol Sosud Khir 2020 ;26(2):86-94

Department of Faculty Surgery #2, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia.

Aim: The purpose of the study was to assess efficacy and safety of using in real clinical practice micronized purified flavonoid fraction (Detralex) in patients with chronic venous oedema.

Patients And Methods: The study enrolled a total of 708 patients presenting with chronic venous disease, belonging to C3EpAsPr according to the CEAP classification (chronic venous oedema), who. depending on the accepted clinical practice by expert physicians were prescribed compression and phlebotropic therapy, as well as undergoing surgical interventions. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jun 24. Epub 2020 Jun 24.

School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia; Vascular Care Centre, Wollongong, New South Wales, Australia.

Objective: The objectives of this study were to determine the incidence of common iliac vein obstruction, gonadal vein incompetence, and renal vein compression/stenosis and to ascertain which referral reasons were associated with common iliac vein obstruction and gonadal vein incompetence in a population symptomatic for chronic venous insufficiency.

Methods: Data were obtained from patients, at least 18 years old, who were referred to a private vascular laboratory for venous duplex ultrasound examination between 2016 and 2017. Transabdominal ultrasound was used to assess the iliac, gonadal, and renal veins in a dedicated protocol. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jun 24. Epub 2020 Jun 24.

Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich.

Objective: Few studies have investigated outcomes after truncal endovenous ablation in patients with combined deep and superficial reflux and no studies have evaluated patient-reported outcomes.

Methods: We investigated the short- and long-term clinical and patient-reported outcomes among patients with and without deep venous reflux undergoing truncal endovenous ablation from 2015 to 2019 in the Vascular Quality Initiative. Preprocedural and postprocedural comparisons were performed using the t-test, χ, or their nonparametric counterpart when appropriate. Read More

Laryngoscope 2020 Jun 24. Epub 2020 Jun 24.

Division of Otorhinolaryngology, Department of Adult and Development Age Human Pathology "Gaetano Barresi", University of Messina, Messina, Italy.

Laryngoscope 2020 Jun 24. Epub 2020 Jun 24.

Vascular Surgery Division, GEPOS Clinic, Telese Terme, Italy.

Med Arch 2020 Apr;74(2):100-104

Department of Radiology, Bach Mai Hospital, Hanoi, Vietnam.

Introduction: Chronic venous insufficiency (CVI) is a chronic condition, triggered by reflux through the saphenous vein network.

Aim: To determine the efficacy of endovenous laser ablation (LA) and radiofrequency ablation (RFA) for CVI treatment in the lower extremities, at the Bach Mai Radiology Center.

Methods: This retrospective study was approved by the institutional review board of Bach Mai Hospital. Read More

Reumatol Clin 2020 Jun 20. Epub 2020 Jun 20.

Instituto de Evaluación Tecnológica en Salud (IETS), Bogotá, Colombia.

Background: Chikungunya (CHIKV), is an endemic RNA virus in some regions of Asia and Africa. In Colombia in 2014, its spread starts explosively and quickly. The presentation of CHIKV is a febrile condition, with musculoskeletal symptoms, which can progress to erosive arthropathy and polyarticular deformity. Read More

Phlebology 2020 Jun 11:268355520932371. Epub 2020 Jun 11.

The Harley Street Heart and Vascular Centre, Gleneagles Hospital, Singapore.

Int J Low Extrem Wounds 2020 Jun 10:1534734620932802. Epub 2020 Jun 10.

Hiroshima University Hospital, Hiroshima, Japan.

Elephantiasis nostras verrucosa (ENV) is a rare dermatological disease associated with chronic lymphedema caused by obesity, soft tissue infection, or chronic venous insufficiency. Although surgical debridement may be sufficient to treat the skin manifestations of ENV, treatment of ENV should focus on reducing lymph stasis to improve the skin changes and prevent recurrence. In this case report, we present the case of a 79-year-old woman who developed obesity-associated ENV in the lower leg. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jun 2. Epub 2020 Jun 2.

Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich.

Objective: Many insurance payers are hesitating to cover interventional treatments in patients with isolated symptomatic varicose veins. In this study, we sought to determine the outcomes of patients with varicose veins who were treated with venous ablation alone or ablation plus phlebectomy using the Vascular Quality Initiative Varicose Vein Registry.

Methods: Using data from the Varicose Vein Registry between January 2015 and March 2019, we investigated immediate postoperative as well as long-term clinical and patient-reported outcomes among patients with documented symptomatic C2 disease undergoing truncal endovenous ablations alone and combined ablation and phlebectomy. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jun 2. Epub 2020 Jun 2.

Department of Dermatology, University Medical Centre Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.

Background: Sclerotherapy is considered to be the method of choice for the treatment of telangiectatic varicose veins (C1 veins). Whereas the use of compression stockings after sclerotherapy is recommended, little is known about the impact of compression on the outcome of sclerotherapy. The aim of this study was to assess the influence of compression on the outcome of injection sclerotherapy of C1 varicose veins. Read More

Br J Community Nurs 2020 Jun;25(Sup6):S6-S13

Research GP, North Cumbria Integrated Care NHS Trust.

Compression bandaging is the mainstay therapy for chronic venous insufficiency and venous leg ulcers, but patient compliance can be challenging due to associated discomfort. The study discussed here aimed to compare AndoFlex TLC Calamine and Coban2 compression bandaging in relation to patient comfort and pruritus symptomology, with severity of pruritus as the primary outcome. This was a multi-centre, prospective, non-blinded, randomised controlled crossover trial involving 39 randomised patients with chronic venous insufficiency patients. Read More

Sao Paulo Med J 2020 Mar 1;138(2):98-105. Epub 2020 Jun 1.

MD. Attending Physician, Department of Cardiovascular Surgery, Karabük Training and Research Hospital, Karabük, Turkey.

Background: Diagnosis and treatment of small saphenous vein (SSV) insufficiency is of utmost importance for relieving chronic venous insufficiency symptoms.

Objectives: To investigate the efficacy and safety of five different treatment approaches among patients with SSV insufficiency.

Design And Setting: Two-center retrospective clinical study, conducted at cardiovascular surgery clinics in a local training and research hospital and a state hospital. Read More

Cardiol Ther 2020 Jun 2. Epub 2020 Jun 2.

Department of Vascular Surgery, Promedica Jobst Vascular Institute, Toledo, OH, USA.

Despite the recognition of the importance of the anatomical extent of venous reflux, its description in medical literature is inconsistent in terms and classifications. Recent international consensus documents provide clear definitions for the three main classes of reflux: segmental, multi-segmental, and axial. This report addresses the most important aspects of the standard definitions of the anatomical extent of venous reflux, the differences between the three classes of reflux, and the challenges of implementing this classification in clinical practice. Read More

J Vasc Surg Venous Lymphat Disord 2020 May 26. Epub 2020 May 26.

Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address:

Objective: To describe typical clinical presentation of patients with microfistular, capillary-venule (CV) malformation as a variant form of arteriovenous malformations (AVM).

Methods: A retrospective clinical analysis of 15 patients with CV-AVM confirmed by a computational flow model enrolled in a prospective database of patients with congenital vascular malformation between January 2008 and May 2018.

Results: The mean age of the patients at first time of presentation was 30 years with balanced sex ratio. Read More

J Vasc Surg Venous Lymphat Disord 2020 May 26. Epub 2020 May 26.

Division of Vascular Surgery, Montefiore Medical Center, Bronx, NY.

Objective: Venous insufficiency is commonly bilateral, and patients often prefer single-episode care compared with staged procedures. Few studies have investigated clinical outcomes after unilateral vs bilateral venous ablation procedures or between staged and concurrent bilateral procedures. Here, we report data from the Vascular Quality Initiative regarding truncal venous ablation for chronic venous insufficiency. Read More

J Diabetes Complications 2020 Sep 15;34(9):107623. Epub 2020 May 15.

Department of Dermatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands. Electronic address:

Background: Peripheral arterial occlusive disease (PAOD) and chronic venous insufficiency (CVI) in organ transplant recipients (OTR) can lead to harmful outcomes. We made an inventory of cutaneous manifestations of PAOD and CVI in OTR in relation with diabetes and other potential risk factors.

Methods: A prospective study in a single center was performed. Read More

Hamostaseologie 2020 Jun 26;40(2):214-220. Epub 2020 May 26.

Department of Vein and Dermatosurgery, Tabea Hospital GmbH and Co KG, Hamburg, Hamburg, Germany.

After acute treatment of deep vein thrombosis, not only the risk but also associated side effects of postthrombotic syndrome (PTS) are often underestimated.There are essentially two main types of PTS.1. Read More

J Vasc Surg Venous Lymphat Disord 2020 May 23. Epub 2020 May 23.

Department of Vascular Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: The objective of this study was to evaluate the efficacy and safety of radiofrequency-induced thermotherapy (RFiTT) combined with transilluminated powered phlebectomy (TIPP) in the treatment of lower limb varicose veins (VVs) in comparison with high ligation and stripping (HLS) combined with TIPP.

Methods: The patients with lower limb VVs were randomly assigned to RFiTT combined with TIPP or HLS combined with TIPP. The primary end point was total closure rate of the great saphenous vein at 12 months. Read More

J Vasc Surg Venous Lymphat Disord 2020 May 22. Epub 2020 May 22.

Departments of Surgery and Radiology, Boston University School of Medicine, Boston, Mass.

Background: Limb compression is a key component of protocols used to heal venous leg ulcers (VLUs). A novel ambulatory pneumatic compression device was tested in comparison with multilayered bandage (MLB) compression systems for the treatment of VLUs in a prospective randomized clinical trial.

Methods: Patients with VLUs measuring 1. Read More

Trials 2020 May 19;21(1):414. Epub 2020 May 19.

PneumoCardioVascular Lab/HUOL Hospital Universitário Onofre Lopes, Empresa Brasileira de Serviços Hospitalares (EBSERRH) Departamento de Fisioterapia Universidade Federal do Rio Grande do Norte, Campus Universitário Central, Caixa Postal 1524/ Campus Universitário Lagoa Nova, Natal, Rio Grande do Norte, CEP: 59078-900, Brazil.

Background: Chronic venous insufficiency (CVI) causes pathophysiological changes in the lower-limb muscles, particularly the calf muscles, and limits ankle range of motion (ROM). These changes reduce functional activities and decrease quality of life (QOL). Although several studies have shown the benefits of exercise (strengthening the calf muscles to improve calf-muscle pumping and QOL) in patients with CVI, few studies are randomized controlled trials. Read More

Adv Ther 2020 Jun;37(6):3031-3032

Krasnoyarsk Interregional Polyclinic No 1, Krasnoyarsk, Russia.

In the original article, there is some error in the Table 2. The correct Table 2 is given below. Read More

Ann Vasc Surg 2020 May 16. Epub 2020 May 16.

Department of Pathology, Medical School, Unicamp, Campinas, SP, Brazil. Electronic address:

Background: The main risk factor associated with basal cell carcinomas (BCCs) is believed to be exposure to ultraviolet radiation (UVR). In the case of lower limb BCC, the frequency is higher in women, possibly because of greater exposure of the leg to UVR. Chronic venous insufficiency (CVI), also more common in women, may have some association with leg BCCs. Read More

Ann Intern Med 2020 May 14. Epub 2020 May 14.

Medical University of Vienna, Vienna, Austria (M.T.).

Background: Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become pandemic, with substantial mortality.

Objective: To evaluate the pathologic changes of organ systems and the clinicopathologic basis for severe and fatal outcomes.

Design: Prospective autopsy study. Read More

Phlebology 2020 May 14:268355520924878. Epub 2020 May 14.

Department of Physiotherapy, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Background: Peripheral pump dysfunction is important in identifying manifestations of chronic venous insufficiency. The association with disease severity may define better treatment strategies.

Objective: To evaluate the association between peripheral muscular pump performance by heel-rise test, age, physical activity, use of compression stockings, and chronic venous insufficiency clinical severity. Read More

J Med Vasc 2020 May 15;45(3):130-146. Epub 2020 Apr 15.

Unité de Médecine Vasculaire, Centre Hospitalier Universitaire de Rennes, 35000 Rennes, France.

Venous insufficiency is a very common disease affecting about 25% of the French population (if we combine all stages of its progression). It is a complex disease and its aetiology has not yet been fully elucidated. Some of its causes are well known, such as valvular dysfunction, vein wall defect, and the suctioning effect common to all varicose veins. Read More

J Pers Med 2020 May 7;10(2). Epub 2020 May 7.

Physiology, School of Medicine, NUI Galway, University Road, Galway H91 TK33, Ireland.

Currently, 1% of the population of the Western world suffers from venous leg ulcers as a result of chronic venous insufficiency. Current treatment involves the use of moist wound healing, compression bandages, and intermittent pneumatic compression. Neuromuscular electrical stimulation is a novel potential new therapeutic method for the promotion of increased lower limb hemodynamics. Read More

J Vasc Surg Venous Lymphat Disord 2020 May 7. Epub 2020 May 7.

Department of Vascular Surgery, Singapore General Hospital, Singapore; Duke-NUS Graduate Medical School, Singapore.

Objective: The aim of A Singapore VenaSeal Real-World Post-Market Evaluation Study (ASVS) was to evaluate the performance of cyanoacrylate closure (CAC) for varicose veins in a prospective multiracial Singaporean Asian cohort. We report early clinical and patient satisfaction outcomes at 3 months after intervention.

Methods: There were 100 patients (151 legs; 156 truncal veins) who underwent CAC between April and December 2018. Read More

J Vasc Surg Venous Lymphat Disord 2020 Jul 4;8(4):565-571. Epub 2020 May 4.

The RANE Center for Venous & Lymphatic Diseases, St. Dominic Hospital, Jackson, Miss.

Objective: Symptoms of chronic venous insufficiency secondary to obstructive iliofemoral disease are often bilateral. The impact of iliofemoral stenting of the more symptomatic lower extremity on clinical outcomes in the less affected contralateral extremity is not clear. Such benefit, secondary to offloading of collaterals, may potentially be of the magnitude that the contralateral extremity does not require intervention. Read More

Eur J Vasc Endovasc Surg 2020 Jun 4;59(6):859-860. Epub 2020 May 4.

Department of Dermatology, Erasmus MC, Rotterdam, the Netherlands.

Phlebology 2020 May 6:268355520922783. Epub 2020 May 6.

Department of Vascular Surgery, Singapore General Hospital, Singapore.

Introduction: The VenaSeal™ Closure System is a non-thermal, non-tumescent venous closure device that employs a cyanoacrylate adhesive to occlude incompetent veins for superficial truncal reflux. The aim was to examine patient, Duplex-defined venous characteristics and treatment-related factors that may predict variances in remnant stump length at the sapheno-femoral and sapheno-popliteal junctions in the peri-procedural period.

Methods: A total of 73 patients (87 legs; 85 great saphenous veins; 11 small saphenous veins) of median age 63 years (range 26-86 years) underwent VenaSeal™ Closure System ablation. Read More