5,043 results match your criteria Chronic Venous Insufficiency


Treatment of Lower Limbs Telangiectasias with Nd: Yag Laser-Prospective Study on 446 Patients.

Curr Health Sci J 2018 Jul-Sep;44(3):235-242. Epub 2018 Jul 15.

Medical Center Dr. Ianosi, Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania.

In the last two decades Nd: YAG laser has become a standard of treatment of telangiectasias of the lower limbs in CEAP stage of chronic venous insufficiency. This paper shows the results of a two years study period of telangiectasias of lower limbs with Nd: YAG laser conducted in a specialised centre in this type of procedures. The study group consisted of 446 patients (21 males and 425 females) with telangiectasias (CEAP) on the lower limbs between January 2016-December 2017. Read More

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http://dx.doi.org/10.12865/CHSJ.44.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311228PMC

Evaluation of Arterial Stiffness Using Pulse Wave Velocity and Augmentation Index in Patients with Chronic Venous Insufficiency.

Int J Vasc Med 2018 2;2018:5437678. Epub 2018 Dec 2.

Karaman State Hospital, Department of Cardiology, 70100 Karaman, Turkey.

Background And Objectives: Chronic venous insufficiency (CVI) is a common pathology of the circulatory system and is associated with a high morbidity for the patients and causes high costs for the healthcare systems. Arterial stiffness has been shown to be a predictor of cardiovascular events and mortality. The relationship between CVI and arterial stiffness using pulse wave velocity (PWV) and augmentation index (Aix) was evaluated in this study. Read More

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http://dx.doi.org/10.1155/2018/5437678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304525PMC
December 2018

Predictors of Chronic Thromboembolic Pulmonary Hypertension.

Kardiologiia 2018 Dec 25;58(12):60-65. Epub 2018 Dec 25.

Pirogov Russian National Research Medical University (RNRMU).

Purpose: to elucidate predictors of development of chronic thromboembolic pulmonary hypertension (CTEPH) after acute pulmonary artery thromboembolism (PTE).

Material And Methods: We included in this study 210 patients hospitalized with diagnosis of submassive and massive PTE from 2013 to 2017. In 1 to 3 years after initial hospitalization these patients were invited for control examination. Read More

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http://dx.doi.org/10.18087/cardio.2018.12.10206DOI Listing
December 2018
1 Read

Prospective study of cryopreserved placental tissue wound matrix in the management of chronic venous leg ulcers.

J Vasc Surg Venous Lymphat Disord 2019 Jan 6. Epub 2019 Jan 6.

Division of Vascular Surgery, Department of Surgery, University of Maryland School of Medicine and Baltimore Veterans Administration Medical Center, Baltimore, Md. Electronic address:

Objective: Chronic venous leg ulcers (VLUs) affect up to 2% of the general population, resulting in a significant socioeconomic burden. Placental tissue that contains mesenchymal stem cells and active growth factors has been shown to be beneficial in healing of chronic wounds. We compared the efficacy of a human viable wound matrix (hVWM) of cryopreserved placental tissue for the treatment of refractory VLUs with standard therapy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2213333X183042
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http://dx.doi.org/10.1016/j.jvsv.2018.09.016DOI Listing
January 2019
1 Read

[Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models].

Praxis (Bern 1994) 2019 Jan;108(1):31-36

1 Institut für Physiologie und Pathophysiologie, Abteilung Herz- und Kreislaufphysiologie, Universität Heidelberg, Deutschland.

Drug-Based Therapy of Varicose Veins from the Perspective of Experimental Models Abstract. Varicose remodeling of the venous wall primarily occurs in the lower extremities and is often associated with venous insufficiency. Although a large part of the western population shows various degrees of varicosis, little is known about the mechanisms driving their formation. Read More

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http://dx.doi.org/10.1024/1661-8157/a003147DOI Listing
January 2019

Effects of compression therapy and venous surgery on tissue oxygenation in chronic venous disease.

Phlebology 2019 Jan 7:268355518822582. Epub 2019 Jan 7.

Department of Vascular Surgery, Waikato Hospital, Hamilton, New Zealand.

Objectives: This study aimed to determine if compression therapy or surgical intervention improves tissue oxygenation in chronic venous disease.

Method: Thirty lower limbs with chronic venous disease were placed into three groups, being compression, open surgical and endovenous ablation. Tissue oxygenation was assessed using a hyperspectral transcutaneous oxygen measurement system. Read More

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http://dx.doi.org/10.1177/0268355518822582DOI Listing
January 2019

A Case Review of Wound Bed Preparation in an Infected Venous Leg Ulcer Utilizing Novel Reticulated Open Cell Foam Dressing with Through Holes during Negative Pressure Wound Therapy with Instillation.

Cureus 2018 Oct 27;10(10):e3504. Epub 2018 Oct 27.

Plastic Surgery, Reading Hospital, Wyomissing, USA.

Chronic venous insufficiency (CVI) and venous leg ulcers (VLUs) have major financial implications for patients and healthcare professionals. VLUs, in particular, require significant care, can be slow to heal, and have a high rate of recurrence. These factors combine to make VLUs a major burden on the healthcare system. Read More

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http://dx.doi.org/10.7759/cureus.3504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314798PMC
October 2018
1 Read

Exploration of robotic-assisted surgical techniques in vascular surgery.

J Robot Surg 2019 Jan 4. Epub 2019 Jan 4.

Department of Vascular and Endovascular Surgery, University of Michigan, Ann Arbor, MI, 48109, USA.

Robotic-assisted surgical approaches for vascular surgery are feasible regarding minimally invasive exposure, dissection, ligation and skeletonization for varicose vein ligation, anterior spine exposure, femoral-popliteal bypass, femoral vein harvest and aortic aneurysm repair. The authors performed a cadaveric exploration to demonstrate proof of concept and feasibility for a robotic-assisted approached. Surgeon autonomy over endoscopic vision, robotic instrumentation and retraction were noted as key benefits over existing open vascular approaches. Read More

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http://dx.doi.org/10.1007/s11701-018-00917-8DOI Listing
January 2019

Protocol for a longitudinal cohort study: determination of risk factors for the development of first venous leg ulcer in people with chronic venous insufficiency, the VEINS (venous insufficiency in South Florida) cohort.

BMJ Open 2019 Jan 3;9(1):e023313. Epub 2019 Jan 3.

Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA.

Introduction: Chronic venous insufficiency (CVI) affects up to one-third of the adult population yet venous leg ulcers (VLU), a significant complication of CVI, only affect 1%-2% of adults in the USA. Why some develop VLU and others do not is unclear. VLU have a significant impact on quality of life and are extremely costly and difficult to treat. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023313DOI Listing
January 2019

Chronic non-healing wounds in geriatrics.

Vnitr Lek 2018 ;64(11):1098-1104

Chronic non-healing wounds represent a frequent comorbidity among geriatric patients. Non-healing wounds increase patients morbidity and mortality and significantly decrease their quality of life. Prognosis of these wounds depends on etiology, overall health condition of the patient and also on the proper treatment. Read More

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January 2018
1 Read

Venoprotective drugs in pigmented purpuric dermatoses: A case report.

J Cosmet Dermatol 2019 Jan 1. Epub 2019 Jan 1.

Dr Ram Manohar Lohia Hospital and Post Graduate Institute of Medical Education and Research, New Delhi, India.

Pigmented purpuric dermatoses (PPD) or capillaritis represent a benign condition, presenting with extravasation of erythrocytes in the skin and prominent hemosiderin deposition. The eruption runs a chronic relapsing course and is resistant to therapy. Capillary fragility, cellular immunity, and microvascular inflammation play important roles in the pathogenesis of PPD. Read More

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http://dx.doi.org/10.1111/jocd.12850DOI Listing
January 2019
1 Read

LivRelief varicose veins cream in the treatment of chronic venous insufficiency of the lower limbs: A 6-week single arm pilot study.

PLoS One 2018 31;13(12):e0208954. Epub 2018 Dec 31.

Department of Medical Science, McMaster University, Hamilton, Ontario, Canada.

Background: Chronic Venous Disease is characterized by morphological abnormalities of the venous system. Affected limbs are classified in increasing clinical severity with the Clinical Etiological Anatomical and Pathological system from C0 to C6. Limbs assessed at C3 through C6 meet the criteria of Chronic Venous Insufficiency. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208954PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312404PMC
December 2018

Mechanochemical ablation for the treatment of superficial venous incompetence: A cohort study of a single centre's early experience.

Phlebology 2018 Dec 30:268355518818339. Epub 2018 Dec 30.

Hull York Medical School, Academic Vascular Surgical Unit, Alderson House, Hull Royal Infirmary, Hull, UK.

Background: Mechanochemical ablation is an innovative non-thermal method of treating symptomatic axial superficial venous incompetence. This is a single-centre cohort study aiming to investigate the technical efficacy and clinical effectiveness at one year.

Methods: Patients with primary, unilateral, symptomatic axial incompetence were offered treatment with mechanochemical ablation using ClariVein® with 1. Read More

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http://dx.doi.org/10.1177/0268355518818339DOI Listing
December 2018

The Efficacy and Safety of Direct Oral Anticoagulants in Patients with Chronic Renal Insufficiency: A Review of the Literature.

Eur J Haematol 2018 Dec 28. Epub 2018 Dec 28.

School of Medicine, The Division of Hematology & Oncology, Oregon Health & Science University, Knight Cancer Institute, Portland, OR.

Direct oral anticoagulants (DOACs) have been shown to be superior to vitamin K antagonists (VKAs) in regards to safety and efficacy in numerous clinical trials, and are now the preferred oral anticoagulant by multiple professional societies. However, patients with significant levels of organ dysfunction were excluded from all major clinical trials, leaving the clinical benefit in these subsets uncertain. Patients with chronic kidney disease (CKD) specifically often require anticoagulation for acute or long-term indications such as venous thromboembolism, atrial fibrillation, or mechanical heart valves. Read More

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http://dx.doi.org/10.1111/ejh.13208DOI Listing
December 2018
1 Read

Long-term outcome of open surgery in CVI patients concerning postoperative complications, perioperative hemodynamics and clinical efficacy, Part II.

Clin Hemorheol Microcirc 2018 Dec 17. Epub 2018 Dec 17.

Dermatological Clinic of the university of Greifswald, Germany.

Background: Chronic venous disease (CVD) is extremely common worldwide with prevalence increasing with age. It is associated with a reduced quality of life, particularly in relation to pain, physical function and mobility. Symptomatic chronic venous insufficiency (CVI) with venous ulcer at its, endpoint, indicates interventional surgery to cure venous reflux therewith promoting wound healing and preventing recurrence. Read More

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http://dx.doi.org/10.3233/CH-189401DOI Listing
December 2018

Polydocanol foam stabilized by liposomes: Supramolecular nanoconstructs for sclerotherapy.

Colloids Surf B Biointerfaces 2018 Dec 12;175:469-476. Epub 2018 Dec 12.

Department of Pharmacy, University of Chieti - Pescara "G. d'Annunzio", Chieti, Italy; Department of Nanomedicine, Houston Methodist Research Institute, 6670 Bertner Avenue, Houston, TX, 77030, USA. Electronic address:

Vascular pathology of the lower limbs is a widespread disease affecting the quality of life for more than 30% of the adult world population. Polydocanol foam is presently the main therapeutic option for treating varicosities, inflammation, and chronic disease which affect the vascular endothelium and blood vessels. Unfortunately, the commercial product contains detergents and surfactants which can provoke several side effects and decrease the efficacy of therapy. Read More

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http://dx.doi.org/10.1016/j.colsurfb.2018.12.027DOI Listing
December 2018
1 Read

Significant differences in patients with a complete insufficiency of the great versus small saphenous vein.

Phlebology 2018 Dec 19:268355518798277. Epub 2018 Dec 19.

3 Department of Dermatology, Venerology and Allergology, Ruhr-University Bochum, Bochum, Germany.

Objectives: Most studies on diagnostics and therapy of saphenous veins focus on great saphenous vein or sum up great and small saphenous vein. This study compares patients with an insufficiency of the great saphenous vein versus small saphenous vein.

Methods: Prospective study including 50 patients with untreated insufficiency of the great saphenous vein or small saphenous vein, respectively. Read More

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http://dx.doi.org/10.1177/0268355518798277DOI Listing
December 2018

An Automatic Classification Method on Chronic Venous Insufficiency Images.

Sci Rep 2018 Dec 18;8(1):17952. Epub 2018 Dec 18.

School of Software Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China.

Chronic venous insufficiency (CVI) affect a large population, and it cannot heal without doctors' interventions. However, many patients do not get the medical advisory service in time. At the same time, the doctors also need an assistant tool to classify the patients according to the severity level of CVI. Read More

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http://dx.doi.org/10.1038/s41598-018-36284-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298992PMC
December 2018
1 Read

Transilluminated Powered Phlebectomy in the Treatment of Large Area Venous Leg Ulcers: a case-control study with 3 years follow-up.

Microcirculation 2018 Dec 16:e12523. Epub 2018 Dec 16.

Department of Vascular Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Objective: To evaluate the efficacy, safety and long-term outcome of transilluminated powered phlebectomy (TIPP) for the adjunct therapy of superficial venous reflux -related venous leg ulcers (VLUs).

Methods: A total of 93 consecutive patients (104 legs) with superficial venous insufficiency-related VLUs who underwent TIPP (53 legs) or conventional phlebectomy (51 legs) between January 2010 and December 2013 were retrospectively studied.

Results: Compared to patients in the conventional phlebectomy group, TIPP patients had larger ulcer areas before surgery (p <. Read More

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http://dx.doi.org/10.1111/micc.12523DOI Listing
December 2018

Dystrophic Calcifications in Chronic Venous Insufficiency.

Authors:
Rukma Govindu

Am J Med Sci 2018 Nov 14. Epub 2018 Nov 14.

Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.amjms.2018.11.005DOI Listing
November 2018

Prospective study of clinical, neurophysiological and urodynamic findings in multiple sclerosis patients undergoing percutaneous transluminal venous angioplasty.

Clin Neurophysiol 2019 Jan 26;130(1):138-144. Epub 2018 Nov 26.

Department of Medicine, Surgery and Neuroscience, Unit of Neurology and Clinical Neurophysiology, University of Siena, Italy. Electronic address:

Objective: Verify whether Percutaneous Transluminal Angioplasty (PTA) may affect neural conduction properties in Multiple Sclerosis (MS) patients, thereby modifying patients' disability, with prospective neurophysiological, urodynamic, clinical and subjective well-being evaluations.

Methods: In 55 out of 72 consecutively screened MS patients, the following procedures were carried out before (T0), at 2-6 months (T1) and at 6-15 months (T2) after a diagnostic phlebography, eventually followed by the PTA intervention if chronic cerebrospinal venous insufficiency (CCSVI) was diagnosed: clinical/objective evaluation (Expanded Disability Status Scale, EDSS), ratings of subjective well-being, evaluation of urodynamic functions and multimodal EPs (visual, acoustic, upper and lower limbs somatosensory and motor evoked potentials).

Results: The number of dropouts was relatively high, and a complete set of neurophysiological and clinical data remained available for 37 patients (19 for urological investigations). Read More

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http://dx.doi.org/10.1016/j.clinph.2018.10.015DOI Listing
January 2019
1 Read

Evaluation of Antibiotic Treatment on the Duration of Hospitalization of Patients with Erysipelas and Bacterial Cellulitis.

Dermatol Ther (Heidelb) 2018 Dec 7. Epub 2018 Dec 7.

Department of Dermatology, University of Rzeszow, Rzeszow, Poland.

Introduction: Erysipelas and bacterial cellulitis are two of the most common infectious skin diseases. They are usually caused by the β-hemolytic group of Streptococcus, and less frequently by other bacteria. The objective of the study was to assess the factors affecting the length of stay of patients admitted to hospital with erysipelas or bacterial cellulitis. Read More

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http://dx.doi.org/10.1007/s13555-018-0276-8DOI Listing
December 2018
2 Reads

[Contemporary data on efficacy of anticoagulant therapy in recanalization of deep veins].

Angiol Sosud Khir 2018 ;24(4):185-190

Department for General Surgery and Urology, Volgograd State Medical University under the RF Ministry of Public Health, Volgograd, Russia.

The article is a literature review containing a detailed description of anticoagulant therapy variants, their efficacy in recanalization of deep veins, as well as patients' compliance to treatment. Russian specialists have demonstrated that the processes of active re-organization of thrombotic masses, in some cases leading to complete clearing of the vessel's lumen from a thrombus, may be observed at terms from 3 to 6 months, with a failure to occur within the above period reportedly followed by formation of irreversible cicatricial-sclerotic alterations in the veins. That is why adequate anticoagulant therapy should be initiated promptly in order to prevent the development of irreversible alterations and a decompensated form of chronic venous insufficiency. Read More

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January 2018
1 Read

Can early detection prevent venous leg ulceration?

Authors:
Michelle Porter

Br J Community Nurs 2018 Dec;23(Sup12):S14-S17

Senior Tissue Viability Clinical Nurse Specialist, Lincolnshire Community Health Services NHS Trust.

Venous leg ulceration is the most common form of leg ulceration, affecting 1.5% of the UK adult population. This was reviewed within the latest best practice statement (2016) which set out to create clear guidance on the assessment, management and preventing the reoccurrence of venous leg ulceration. Read More

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http://dx.doi.org/10.12968/bjcn.2018.23.Sup12.S14DOI Listing
December 2018
1 Read

[The application of combined low-intensity laser therapy for the treatment of the patients presenting with trophic ulcers associated with chronic venous insufficiency of the lower extremities].

Vopr Kurortol Fizioter Lech Fiz Kult 2018 ;95(6):27-33

O.K. Skobelkin State Scientific Centre of Laser Medicine, Russian Federal Medico-Biological Agency, Moscow, Russia.

Aim: The objective of the present study was the evaluation of the effectiveness of the combined treatment of the patients presenting with trophic ulcers associated with chronic venous insufficiency of the lower extremities of venous etiology with the application of low-intensity laser therapy (LILT) at different wavelengths.

Material And Methods: The study included the patients presenting with chronic venous insufficiency (CVI) (class C6 in accordance with the CEAP clinical classification). The ultrasonic Doppler examination (USDG) of the lower extremities revealed valvular insufficiency in the saphenous veins in 98. Read More

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http://dx.doi.org/10.17116/kurort20189506127DOI Listing
January 2018
7 Reads

Thrombophilia in non-thrombotic chronic venous disease of the lower limb - a systematic review.

Br J Haematol 2018 Dec;183(5):703-716

Department of Vascular Surgery, Imperial College London, Charing Cross Hospital, London, UK.

Chronic venous disease (CVD) represents a significant healthcare burden. Thrombophilia is proposed as a risk factor, particularly for post-thrombotic CVD. A systematic review was performed to determine the relationship between thrombophilia and non-thrombotic CVD. Read More

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http://dx.doi.org/10.1111/bjh.15692DOI Listing
December 2018
1 Read

Predicting Renal Function Outcomes After Partial and Radical Nephrectomy.

Eur Urol 2018 Nov 23. Epub 2018 Nov 23.

Department of Urology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Background: Partial nephrectomy (PN) is generally favored for cT1 tumors over radical nephrectomy (RN) when technically feasible. However, it can be unclear whether the additional risks of PN are worth the magnitude of renal function benefit.

Objective: To develop preoperative tools to predict long-term estimated glomerular filtration rate (eGFR) beyond 30d following PN and RN, separately. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183087
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http://dx.doi.org/10.1016/j.eururo.2018.11.021DOI Listing
November 2018
10 Reads

Duplex ultrasound findings and clinical classification of lower extremity chronic venous insufficiency in a Thai population.

J Vasc Surg Venous Lymphat Disord 2018 Nov 23. Epub 2018 Nov 23.

Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: The objective of this study was to evaluate the association between the clinical classification of chronic venous insufficiency and duplex ultrasound findings.

Methods: A total of 1010 limbs with clinically suspected chronic venous insufficiency were stratified according to the Clinical, Etiology, Anatomy, and Pathophysiology (CEAP) classification and underwent duplex ultrasound evaluation consecutively between January 2012 and June 2015. Venous thrombosis, venous reflux, and anatomic distribution of the deep and superficial venous systems were investigated across the CEAP clinical classes. Read More

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http://dx.doi.org/10.1016/j.jvsv.2018.08.012DOI Listing
November 2018
1 Read

Endovenous Photocoagulation Using a Diode Laser for Complicated Varicose Veins Related to Stasis Ulcers.

Ann Plast Surg 2019 Jan;82(1S Suppl 1):S103-S107

Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University.

Background: The objective of this study was to assess the efficacy and safety of endovenous laser photocoagulation (EVLP) at a wavelength of 810 nm for treating complicated venous insufficiency associated with venous ulcers.

Materials And Methods: A retrospective review of 110 patients with 180 legs having chronic venous insufficiencies associated with varicose veins treated over an 8-year period was conducted. Patients ranged from 16 to 80 years of age and included 85 women and 25 men. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001726DOI Listing
January 2019
4 Reads

Utility of Skin Biopsy and Culture in the Diagnosis and Classification of Chronic Ulcers: A Single-Institution, Retrospective Study.

Am J Dermatopathol 2018 Nov 15. Epub 2018 Nov 15.

Department of Pathology, University of Washington, Seattle, WA.

In the United States, chronic ulcers affect 6.5 million people, with a cost of ≈$20 million annually. The most common etiology of chronic ulcers in the United States is venous stasis, followed by arterial insufficiency and neuropathic ulcers. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001299DOI Listing
November 2018
6 Reads

Acroangiodermatitis of Mali (Pseudo-Kaposi Sarcoma) Associated with Chronic Venous Insufficiency and Obesity: A Case Report.

Wounds 2018 Nov;30(11):E105-E107

College of Medicine, Taif University, Taif, Saudi Arabia.

Introduction: Acroangiodermatitis, also known as psesudo-Kapsoi sarcoma, is a rare and benign angioproliferative malady. It presents clinically as purple-colored plaques, patches, or nodules resembling Kaposi sarcoma and is often related to chronic venous insufficiency, arteriovenous malformation of the legs, paralyzed limbs, and residual limbs. Obesity is a risk factor for venous insufficiency and could be related to acroangiodermatitis. Read More

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November 2018
14 Reads

Free flap and kickstand external fixator in foot and ankle soft tissue reconstruction. The versatility of a microsurgical-friendly application of an orthopedic device.

Injury 2018 Nov;49 Suppl 3:S105-S109

Division of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.

Introduction: Foot and ankle are prone to injuries and often require free flap for complex soft tissue reconstruction due to the insufficiency of local soft tissue. Lower limb reconstruction can be commonly compromised by venous insufficiency, and the elevation of the limb represents a critical component of the postoperative care. This study aims to explore the versatility of combining free soft tissue flap reconstruction for complex foot and ankle defect with a temporary Kickstands External Fixator (KEF) placement. Read More

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http://dx.doi.org/10.1016/j.injury.2018.09.048DOI Listing
November 2018
1 Read

Central Venous Pathologies: Treatments and Economic Impact.

Authors:
Kenneth Ouriel

Methodist Debakey Cardiovasc J 2018 Jul-Sep;14(3):166-172

SYNTACTX, NEW YORK, NEW YORK.

Chronic venous insufficiency (CVI) is responsible for significant costs to society in the form of medical and surgical treatment and, importantly, unmeasurable lost work productivity due to pain and disability. Symptomatic chronic central vein obstruction, a cause of CVI, is potentially treatable using open surgical and endovascular techniques to restore vessel patency. Although upper extremity central vein obstruction often requires an open surgical procedure for durable relief, endovascular stents have proven remarkably useful for iliofemoral disease. Read More

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http://dx.doi.org/10.14797/mdcj-14-3-166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217555PMC
November 2018
10 Reads

Vein Size and Disease Severity in Chronic Venous Diseases.

Int J Angiol 2018 Dec 6;27(4):185-189. Epub 2018 Apr 6.

Department of Cardiovascular Diseases and Diabetes Biology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.

Given the high prevalence of chronic venous diseases (CVD), defining criteria to screen patients who are in need for intervention is attaining primacy. An important clinical criterion for treating CVD is incompetence of larger veins. We have assessed the association of size of afflicted veins with disease severity in patients with CVD to define an acceptable criterion to identify patients who need intervention. Read More

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http://dx.doi.org/10.1055/s-0038-1639355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221802PMC
December 2018
7 Reads

Rutosides for treatment of post-thrombotic syndrome.

Cochrane Database Syst Rev 2018 11 8;11:CD005625. Epub 2018 Nov 8.

Division of Epidemiology and Public Health, University of Nottingham, C120, Clinical Sciences Building - Ph2, City Hospital Campus, Hucknall Road, Nottingham, UK, NG5 1PB.

Background: Post-thrombotic syndrome (PTS) is a long-term complication of deep venous thrombosis (DVT) that is characterised by pain, swelling, and skin changes in the affected limb. One in three patients with DVT will develop post-thrombotic sequelae within five years. Rutosides are a group of compounds derived from horse chestnut (Aesculus hippocastanum), a traditional herbal remedy for treating oedema formation in chronic venous insufficiency (CVI). Read More

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http://doi.wiley.com/10.1002/14651858.CD005625.pub4
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http://dx.doi.org/10.1002/14651858.CD005625.pub4DOI Listing
November 2018
12 Reads

Rutosides for prevention of post-thrombotic syndrome.

Cochrane Database Syst Rev 2018 11 8;11:CD005626. Epub 2018 Nov 8.

Division of Epidemiology and Public Health, University of Nottingham, C120, Clinical Sciences Building - Ph2, City Hospital Campus, Hucknall Road, Nottingham, UK, NG5 1PB.

Background: Post-thrombotic syndrome (PTS) is a long-term complication of deep venous thrombosis (DVT) that is characterised by pain, swelling, and skin changes in the affected limb. One in three patients with DVT will develop post-thrombotic sequelae within five years. The current standard care for the prevention of PTS following DVT is elastic compression stockings. Read More

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http://doi.wiley.com/10.1002/14651858.CD005626.pub4
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http://dx.doi.org/10.1002/14651858.CD005626.pub4DOI Listing
November 2018
13 Reads

Multi-observer comparison study between unenhanced quiescent-interval single-shot magnetic resonance angiography and invasive carbon dioxide angiography in patients with peripheral arterial disease and chronic renal insufficiency.

Eur J Radiol 2018 Nov 28;108:140-146. Epub 2018 Sep 28.

Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.

Objectives: Non-contrast-enhanced quiescent-interval single-shot magnetic resonance angiography (QISS-MRA) and invasive carbon dioxide (CO2) angiography are suggested as nephroprotective methods for accurate staging of peripheral arterial disease (PAD) in patients with chronic renal insufficiency (CRI). The aim of our study was to compare the image quality of both examinations.

Methods: 16 consecutive PAD patients with highly impaired renal function (estimated glomerular filtration rate (eGFR) < 30 ml/min/1. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183034
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http://dx.doi.org/10.1016/j.ejrad.2018.09.029DOI Listing
November 2018
3 Reads

Sulodexide in venous disease.

J Thromb Haemost 2019 Jan 7;17(1):31-38. Epub 2018 Dec 7.

Division of Cardiovascular Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

Sulodexide is a glycosaminoglycan extracted from porcine intestinal mucosa. The purpose of this review is to discuss sulodexide's complex pharmacological profile and its clinical applications for venous disease. Sulodexide has wide-ranging biological effects on the vascular system, including antithrombotic, profibrinolytic, anti-inflammatory, endothelial protective and vasoregulatory effects. Read More

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http://doi.wiley.com/10.1111/jth.14324
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http://dx.doi.org/10.1111/jth.14324DOI Listing
January 2019
7 Reads

Chronic venous insufficiency and varicose veins of the lower extremities.

Korean J Intern Med 2018 Oct 26. Epub 2018 Oct 26.

Division of Interventional Cardiology, Calhoun Cardiology Center, UConn Health, University of Connecticut School of Medicine, Farmington, CT, USA.

Chronic venous insufficiency (CVI) of the lower extremities manifests itself in various clinical spectrums, ranging from asymptomatic but cosmetic problems to severe symptoms, such as venous ulcer. CVI is a relatively common medical problem but is often overlooked by healthcare providers because of an underappreciation of the magnitude and impact of the problem, as well as incomplete recognition of the various presenting manifestations of primary and secondary venous disorders. The prevalence of CVI in South Korea is expected to increase, given the possible underdiagnoses of CVI, the increase in obesity and an aging population. Read More

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http://kjim.org/journal/view.php?doi=10.3904/kjim.2018.230
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http://dx.doi.org/10.3904/kjim.2018.230DOI Listing
October 2018
12 Reads

RESULTS OF EVLT: RADIAL FIBER VERSUS BARE-TIP FIBER WITH CHEMICAL ASSISTANCE.

Georgian Med News 2018 Sep(282):12-17

Odessa National Medical University, Ukraine.

Purpose of the study - comparison of the effectiveness of various methods of endovenous laser coagulation of the great saphenous vein, searching the optimal scheme for the treatment of chronic venous insufficiency. Retrospective analyze of 318 clinical cases of combined surgical treatment using various methods of thermoablation (bare-tip fiber, radial fiber, simultaneous thermoablation and echosclerobliteration) of a great saphenous vein. By the parameter of the great saphenous vein occlusion, the results in the group of simultaneous thermoablation and echosclerobliteration surpassed the bare-tip thermoablation group results and were comparable with the results of radial thermoablation. Read More

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September 2018
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Combined therapy in the treatment of mixed etiology leg ulcer - case report.

Ther Clin Risk Manag 2018 8;14:1915-1921. Epub 2018 Oct 8.

Department of Internal Medicine, Angiology and Physical Medicine, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Bytom, Poland.

The most frequent causes of leg ulcers are chronic venous disease (CVD) related mainly to venous hypertension and peripheral arterial disease (PAD) related to disseminated atheromatous lesions in lower limb arteries. In 15%-21% of patients, ulcers of mixed venous-arterial etiology occur, which are usually more resistant for conservative therapy (compression therapy, pharmacotherapy, wearing elastic stockings, leg elevation and massage, change of lifestyle, and regular physical exercises). The contemporary model of complex therapy of leg ulcers in the course of chronic venous and arterial insufficiency more often also comprises numerous physical therapy procedures as associated therapy. Read More

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http://dx.doi.org/10.2147/TCRM.S176321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183550PMC
October 2018
6 Reads

Hepatic encephalopathy: Sometimes more portal than hepatic.

J Gastroenterol Hepatol 2018 Oct 21. Epub 2018 Oct 21.

Department of Surgery, School of Medicine, Complutense University of Madrid, Madrid, Spain.

Hepatic encephalopathy is a severe complication of both chronic and acute liver diseases. The term hepatic encephalopathy stems from the belief that hepatic insufficiency is its fundamental etiopathogenic factor. However, most clinical cases show liver failure along with mesenteric venous portal hypertension. Read More

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http://doi.wiley.com/10.1111/jgh.14514
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http://dx.doi.org/10.1111/jgh.14514DOI Listing
October 2018
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The Discord Outcome Analysis (DOA) as a Reporting Standard at Three Months and Five Years in Randomised Varicose Vein Treatment Trials.

Eur J Vasc Endovasc Surg 2018 Oct 17. Epub 2018 Oct 17.

Josef Pflug Vascular Laboratory, Ealing Hospital, Middlesex, UK; Department of Surgery and Cancer, Imperial College, London, UK; West London Vascular and Interventional Centre, Northwick Park Hospital, Harrow, UK. Electronic address:

Objectives: Treatment success for chronic superficial venous insufficiency could be defined as an improvement in three domains: (i) disease specific quality of life, (ii) clinical severity, (iii) reflux. The aim was to report these at five years using a Venn diagram to profile the outcomes: a discord outcome analysis (DOA).

Materials And Methods: Patients (n = 50 patients/legs in each treated group) were randomised to endovenous laser ablation (EVLA) with concurrent phlebectomies vs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10785884183068
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http://dx.doi.org/10.1016/j.ejvs.2018.09.013DOI Listing
October 2018
15 Reads

[Prospective comparative study of remote results of surgical treatment of patients with varicothrombophlebitis].

Angiol Sosud Khir 2018;24(3):77-84

Saratov State Medical University named after V.I. Razumovsky under the Ministry of Public Health of the Russian Federation, Saratov, Russia.

The authors examined the effect of the presence of undifferentiated connective tissue dysplasia (UCTD) on the clinical course of lower-limb varicose veins (LLVV) and acute varicothrombophlebitis (AVTP) in patients after the Troyanov-Trendelenburg operation. We carried out a prospective comparative study of the remote results during three years after the Troyanov-Trendelenburg operation in a total of 132 patients suffering from AVTP. The Study Group included 67 patients found to have more than four phenotypic traits of UCTD, thus suggesting the presence of UCTD. Read More

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December 2018
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[Ultrasonographic examination of major veins of lower limbs and pelvic veins in pregnant women].

Angiol Sosud Khir 2018;24(3):70-75

Interregional Clinical and Diagnostic Centre, Kazan, Russia; Department of Surgical Diseases No2 of the Kazan State Medical University, Kazan, Russia.

The problem of chronic venous insufficiency in women during pregnancy is of current concern. A total of 115 pregnant women in the first, second and third trimesters of gestation were examined in a stage-wise manner. During the first stage we conducted a comprehensive clinical study with the obligatory consultation by the obstetrician-gynaecologist. Read More

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December 2018
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Long-term outcome of open surgery in CVI patients concerning postoperative complications, perioperative hemodynamics and clinical efficacy, Part I.

Clin Hemorheol Microcirc 2018 Oct 11. Epub 2018 Oct 11.

Dermatological Clinic of the University of Greifswald, Germany.

Background: Chronic venous disease (CVD) is extremely common worldwide. The prevalence is increasing with age and is associated with a reduced quality of life, particularly in relation to pain, physical function and mobility. Symptomatic chronic venous insufficiency (CVI) with venous ulcer at its' endpoint, indicates interventional surgery to cure venous reflux therewith promoting wound healing and preventing recurrence. Read More

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http://dx.doi.org/10.3233/CH-189305DOI Listing
October 2018
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Cellulitis and bacteria in peripheral lymphedema.

Authors:
W L Olszewski

Lymphology 2018 ;51(2):54-56

Department of Surgery, Central Clinical Hospital, Ministry of Internal Affairs, Warsaw, Poland.

Counterpoint to the article: Peculiar Clinical Features of Cellulitis in Peripheral Lymphedema, K. Suehiro, et al. Lymphology Vol 51, No 2, pp 47-53. Read More

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January 2018
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Peculiar clinical features of cellulitis in peripheral lymphedema.

Lymphology 2018 ;51(2):47-53

Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.

Although the occurrence of cellulitis in lymphedema (LE) is believed to be an infection-related event, many findings in its clinical course seem to suggest that it is unlikely to be an infection. Therefore, we tried to clarify the specific features of cellulitis in LE. In-hospital courses of cellulitis obtained from medical charts were reviewed in the patients with leg LE (LE; 24 patients, 72admissions), chronic venous insufficiency (CVI; 28 patients, 29 admissions), and leg cellulitis secondary to wound infection without underlying disease (N; 42 patients, 42 admissions). Read More

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January 2018
2 Reads