560 results match your criteria Chronic Respiratory Disease[Journal]


Clinical outcomes of theophylline use as add-on therapy in patients with chronic obstructive pulmonary disease: A propensity score matching analysis.

Chron Respir Dis 2019 Jan-Dec;16:1479973118815694

1 School of Pharmaceutical Sciences, University of Phayao, Phayao, Thailand.

To examine clinical outcomes of theophylline use in patients with chronic obstructive pulmonary disease (COPD) receiving inhaled corticosteroids (ICS) and long-acting beta-2 agonists (LABA). Electronic data from five hospitals located in Northern Thailand between January 2011 and December 2015 were retrospectively collected. Propensity score (PS) matching (2:1 ratio) technique was used to minimize confounding factors. Read More

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http://dx.doi.org/10.1177/1479973118815694DOI Listing

Low income as a determinant of exercise capacity in COPD.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809491

1 Mindful Breathing Laboratory, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, MN, USA.

Exercise capacity (EC) is a critical outcome in chronic obstructive lung disease (chronic obstructive pulmonary disease (COPD)). It measures the impact of the disease and the effect of specific interventions like pulmonary rehabilitation (PR). EC determines COPD prognosis and is associated with health-care utilization and quality of life. Read More

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http://dx.doi.org/10.1177/1479972318809491DOI Listing
November 2018
5 Reads

Cluster analysis identifying patients with COPD at high risk of 2-year all-cause mortality.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809452

1 Laboratory of Research in Respiratory Physiotherapy (LFIP), Universidade Estadual de Londrina (UEL), Londrina, Brazil.

The objective of the article is to identify clusters of patients with COPD according to factors known to be associated with mortality and to verify whether clusters' assignment is associated with 2-year mortality. Patients ( n = 141) were evaluated by bioelectrical impedance, maximal inspiratory pressure (MIP), one-repetition maximum test of the quadriceps femoris (1RMQF) and BODE index (body mass index; airflow obstruction (spirometry); dyspnea (modified Medical Research Council scale); and exercise capacity (6-minute walk test (6MWT) distance). Vital status was retrospectively checked 2 years after the assessments, and time to death was quantified for those deceased in this period. Read More

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http://dx.doi.org/10.1177/1479972318809452DOI Listing
November 2018

Pain in patients with chronic obstructive pulmonary disease indicated for post-acute pulmonary rehabilitation.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809456

1 Department of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands.

Pain is a significant problem in stable chronic obstructive pulmonary disease (COPD) and is associated with other symptoms, worse health status and lower functional status. Not much is known about pain in unstable disease. The primary aim of the present study is to investigate prevalence, characteristics and relationships of pain in patients with COPD hospitalized for an acute exacerbation (AECOPD) and indicated for post-acute pulmonary rehabilitation (PR). Read More

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http://journals.sagepub.com/doi/10.1177/1479972318809456
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http://dx.doi.org/10.1177/1479972318809456DOI Listing
November 2018
4 Reads
2.310 Impact Factor

The effect of comorbidity severity on pulmonary rehabilitation outcomes in chronic obstructive pulmonary disease patients.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809472

2 Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey.

Clinical Trial Number:: NCT03319108. Read More

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http://dx.doi.org/10.1177/1479972318809472DOI Listing
November 2018

Early readmission and mortality in acute exacerbation of chronic obstructive pulmonary disease with community-acquired pneumonia.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809480

1 Department of Internal Medicine, Wonju College of Medicine, Yonsei University, Gangwon, Korea.

Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are important causes of hospital admission and mortality. Pneumonia is a major contributor to hospitalization for AECOPD and has a close relationship with poor outcomes. We performed a prospective cohort study to evaluate the prognosis of AECOPD patients with or without community-acquired pneumonia (CAP) who hospitalized from January 2012 to December 2015. Read More

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http://dx.doi.org/10.1177/1479972318809480DOI Listing
November 2018
1 Read

Differences in clinical features of acute exacerbation between connective tissue disease-associated interstitial pneumonia and idiopathic pulmonary fibrosis.

Chron Respir Dis 2019 Jan-Dec;16:1479972318809476. Epub 2018 Oct 31.

1 Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a devastating condition that frequently occurs in the advanced stage of IPF. However, the clinical features in AE of connective tissue disease-associated interstitial pneumonia (AE-CTD-IP) have not been well-established. The aim of this study was to clarify the clinical features of AE-CTD-IP and to compare them with those of AE-IPF. Read More

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http://dx.doi.org/10.1177/1479972318809476DOI Listing
October 2018
7 Reads

Patient measures for respiratory patients.

Authors:
Suzanne C Lareau

Chron Respir Dis 2019 Jan-Dec;16:1479972318796221. Epub 2018 Oct 24.

College of Nursing, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.

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http://dx.doi.org/10.1177/1479972318796221DOI Listing
October 2018

Development of a core outcome set for trials investigating the long-term management of bronchiectasis.

Chron Respir Dis 2019 Jan-Dec;16:1479972318804167. Epub 2018 Oct 3.

1 School of Pharmacy, Queen's University Belfast, Belfast, Northern Ireland.

Heterogeneity in outcomes measured in trials limits accurate comparison of bronchiectasis studies. A core outcome set (COS) is an agreed, standardized set of outcomes that should be measured in trials for specific clinical areas. A COS for bronchiectasis could encourage consistency in future studies. Read More

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http://journals.sagepub.com/doi/10.1177/1479972318804167
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http://dx.doi.org/10.1177/1479972318804167DOI Listing
October 2018
2 Reads

COPD patients in need of palliative care: Identification after hospitalization through the surprise question.

Chron Respir Dis 2019 Jan-Dec;16:1479972318796219. Epub 2018 Sep 16.

1 Spaarne Gasthuis, Haarlem, the Netherlands.

Currently, few patients suffering from chronic obstructive pulmonary disease (COPD) who might benefit from a palliative care approach are referred to a palliative care team. Tools to identify patients eligible for a palliative care approach have been found to be difficult to apply in daily practice. Therefore, there is need for a simple and easily applicable tool to identify those patients who would benefit from referral to a palliative care team. Read More

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http://dx.doi.org/10.1177/1479972318796219DOI Listing
September 2018

Testosterone replacement therapy and hospitalization rates in men with COPD.

Chron Respir Dis 2019 Jan-Dec;16:1479972318793004. Epub 2018 Sep 11.

2 Sealy Center on Aging, University of Texas Medical Branch, Galveston, TX, USA.

Testosterone deficiency is common in men with chronic obstructive pulmonary disease (COPD) and may exacerbate their condition. Research suggests that testosterone replacement therapy (TRT) may have a beneficial effect on respiratory outcomes in men with COPD. To date, however, no large-scale nationally representative studies have examined this association. Read More

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http://dx.doi.org/10.1177/1479972318793004DOI Listing
September 2018
2.310 Impact Factor

Azithromycin or erythromycin? Macrolides for non-cystic fibrosis bronchiectasis in adults: A systematic review and adjusted indirect treatment comparison.

Chron Respir Dis 2019 Jan-Dec;16:1479972318790269. Epub 2018 Aug 12.

1 Department of Preclinical Medicine, Guiyang University of Chinese Medicine, Guiyang, Guizhou, China.

Non-cystic fibrosis (non-CF) bronchiectasis is a condition characterized by an airway inflammatory response to bacterial pathogens. Frequent exacerbations have a major influence on the quality of life. Macrolide antibiotics have not only antibacterial but also immune-regulation effects. Read More

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http://dx.doi.org/10.1177/1479972318790269DOI Listing
August 2018
2 Reads

Flow and airway pressure analysis for detecting ineffective effort during mechanical ventilation in neuromuscular patients.

Chron Respir Dis 2019 Jan-Dec;16:1479972318790267. Epub 2018 Jul 31.

1 Service Physiologie et Explorations-Fonctionnelles, INSERM CIC 1429, AP-HP, Hôpital Raymond Poincaré, Garches, France.

Ineffective efforts (IEs) are among the most common types of patient-ventilator asynchrony. The objective of this study is to validate IE detection during expiration using pressure and flow signals, with respiratory effort detection by esophageal pressure (Pes) measurement as the reference, in patients with neuromuscular diseases (NMDs). We included 10 patients diagnosed with chronic respiratory failure related to NMD. Read More

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http://journals.sagepub.com/doi/10.1177/1479972318790267
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http://dx.doi.org/10.1177/1479972318790267DOI Listing
July 2018
4 Reads

Variation in treatment strategies for the eradication of Pseudomonas aeruginosa in primary ciliary dyskinesia across European centers.

Chron Respir Dis 2019 Jan-Dec;16:1479972318787919. Epub 2018 Jul 18.

2 Danish PCD and chILD Centre, CF Centre Copenhagen, Paediatric Pulmonary Service, Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Denmark.

Primary ciliary dyskinesia (PCD) is a rare disease causing motile cilia dysfunction, recurrent airway infection, and bronchiectasis. Airway infection management strategies are borrowed from cystic fibrosis. The aim of this study is to describe the management of airway infection with Pseudomonas aeruginosa ( PA) in children and adults with PCD across European centers. Read More

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http://dx.doi.org/10.1177/1479972318787919DOI Listing
July 2018
1 Read

Inhaler usability of a pressurized metered dose inhaler and a soft mist inhaler in patients with COPD: A simulated-use study.

Chron Respir Dis 2019 Jan-Dec;16:1479972318787914. Epub 2018 Jul 17.

2 AstraZeneca, Gaithersburg, MD, USA.

The objective of this study was to evaluate task performance and handling errors with soft mist inhalers (SMIs) or pressurized metered-dose inhalers (pMDIs) among patients with chronic obstructive pulmonary disease (COPD) experienced with, but not recently trained in, using these devices. This exploratory, noninterventional, simulated-use study (D5970R00004) assessed handling/usability of SMIs and pMDIs in inhaler-experienced patients with COPD (40-78 years; diagnosis ≥6 months). Patients received a device and instruction-for-use leaflet but no training and were recorded while performing tasks required for checking the device, priming, and dosing. Read More

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http://dx.doi.org/10.1177/1479972318787914DOI Listing
July 2018
2 Reads

Health-related quality of life, treatment adherence and psychosocial support in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension.

Chron Respir Dis 2019 Jan-Dec;16:1479972318787906. Epub 2018 Jul 16.

5 Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) share similar quality of life impairment. The aim of the present study was to investigate health-related quality of life (HRQoL) and its relation to the perception of treatment and psychosocial support among PAH and CTEPH patients. All adult PAH or CTEPH patients in the Swedish Pulmonary Arterial Hypertension Register were invited to participate in a national cohort survey. Read More

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http://dx.doi.org/10.1177/1479972318787906DOI Listing
July 2018
8 Reads

The influence of South Asian ethnicity on the incremental shuttle walk test in UK adults.

Chron Respir Dis 2018 Aug 4;15(3):241-249. Epub 2018 Jul 4.

1 Centre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre - Respiratory, NIHR Institute of Lung Health, Leicester, UK.

The objective of this study was to compare incremental shuttle walking test (ISWT) performance between South Asian and Caucasian British adults, identify predictors of ISWT distance and produce ethnicity-specific reference equations. Data from a mixed gender sample aged 40-75 years from Leicestershire, United Kingdom, were selected for analyses. Analysis of covariance determined differences in ISWT performance between South Asian and Caucasian British ethnic groups. Read More

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http://dx.doi.org/10.1177/1479972318785832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100169PMC
August 2018
12 Reads

Comparison of procalcitonin, C-reactive protein, white blood cell count and clinical status in diagnosing pneumonia in patients hospitalized with acute exacerbations of COPD: A prospective observational study.

Chron Respir Dis 2019 Jan-Dec;16:1479972318769762. Epub 2018 May 30.

4 Department of Clinical Chemistry, Trondheim University Hospital, Trondheim, Norway.

Lower respiratory tract infection is the most common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of the present study was to compare the accuracy of procalcitonin (PCT), C-reactive protein (CRP) and white blood cell count (WBC) as single diagnostic tests and in combination with clinical signs and symptoms to diagnose pneumonia in patients hospitalized with AECOPD. This was a prospective, single centre observational study. Read More

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http://dx.doi.org/10.1177/1479972318769762DOI Listing
May 2018
1 Read

Depression is a major determinant of both disease-specific and generic health-related quality of life in people with severe COPD.

Chron Respir Dis 2019 Jan-Dec;16:1479972318775422. Epub 2018 May 9.

1 Department of Internal Medicine, School of Medicine, Pusan National University, Busan, Republic of Korea.

The quality of life of patients with chronic obstructive pulmonary disease (COPD) decreases significantly as the disease progresses; those with severe COPD are affected most. This article investigates predictors of the disease-specific and generic health-related quality of life (HRQL) in patients with severe COPD. This multicentre prospective cross-sectional study enrolled 80 patients with severe COPD. Read More

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http://dx.doi.org/10.1177/1479972318775422DOI Listing
May 2018
4 Reads

Relationship of spirometric, body plethysmographic, and diffusing capacity parameters to emphysema scores derived from CT scans.

Chron Respir Dis 2019 Jan-Dec;16:1479972318775423. Epub 2018 May 9.

10 Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Ludwig-Maximilians-Universität München, Munich, Germany.

Phenotyping of chronic obstructive pulmonary disease (COPD) with computed tomography (CT) is used to distinguish between emphysema- and airway-dominated type. The phenotype is reflected in correlations with lung function measures. Among these, the relative value of body plethysmography has not been quantified. Read More

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http://dx.doi.org/10.1177/1479972318775423DOI Listing
May 2018
2 Reads

Feasibility study to assess the effect of a brief mindfulness intervention for patients with chronic obstructive pulmonary disease: A randomized controlled trial.

Chron Respir Dis 2018 Nov 24;15(4):400-410. Epub 2018 Apr 24.

2 Population Health Research Institute, St George's, University of London, London, UK.

Psychological distress is common among patients with chronic obstructive pulmonary disease (COPD). This study aimed to assess whether a 10-minute mindfulness intervention reduces distress and breathlessness, improves mood and increases mindfulness among hospital inpatients following acute exacerbation of COPD.Fifty patients were recruited following an acute admission. Read More

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http://dx.doi.org/10.1177/1479972318766140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234574PMC
November 2018
1 Read

Why are COPD patients unable to complete the outpatient pulmonary rehabilitation program?

Chron Respir Dis 2018 Nov 19;15(4):411-418. Epub 2018 Apr 19.

2 Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey.

This study aims to compare demographic and clinical characteristics of chronic obstructive pulmonary disease (COPD) patients who complete and fail to complete outpatient pulmonary rehabilitation (PR) program and to determine the reasons for not completing the program. Patients with COPD referred to the PR program were divided into two groups: Those who completed the program were classified as group 1 and those who did not complete were classified as group 2, and their data were compared. Patients who failed to complete the program were contacted through phone and asked why they ceased their participation in the program. Read More

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http://dx.doi.org/10.1177/1479972318767206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234569PMC
November 2018
2 Reads

Chronic bronchitis: High prevalence in never smokers and underdiagnosis- A population-based study in Colombia.

Chron Respir Dis 2019 Jan-Dec;16:1479972318769771. Epub 2018 Apr 18.

1 Research Department, Fundacion Neumologica Colombiana, Bogota, Colombia.

The objective of the article was to establish the prevalence, underdiagnosis, and risk factors of chronic bronchitis (CB) in a general population in five Colombian cities. Cross-sectional study using a probabilistic sampling technique in five Colombian cities was adopted. The CB definition was "cough and expectoration for three or more months per year for at least two consecutive years. Read More

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http://dx.doi.org/10.1177/1479972318769771DOI Listing
April 2018
2 Reads

Prospective risk of osteoporotic fractures in patients with advanced chronic obstructive pulmonary disease.

Chron Respir Dis 2019 Jan-Dec;16:1479972318769763. Epub 2018 Apr 16.

1 Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, UHL, Leicester, UK.

Despite the high prevalence of osteoporosis in chronic obstructive pulmonary disease (COPD) patients, the fracture risk prediction tools are not routinely undertaken in the management of COPD. We quantified fracture risk using a validated risk prediction tool (Fracture Risk Assessment (FRAX®)) and determined potential bone-protection treatment needs in patients with advanced COPD. The 10-year probability of major osteoporotic or hip fracture was calculated using the FRAX tool in a cohort of patients attending a hospital complex COPD service. Read More

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http://dx.doi.org/10.1177/1479972318769763DOI Listing
April 2018
2 Reads

Adherence to long-term oxygen therapy in patients with chronic obstructive pulmonary disease.

Chron Respir Dis 2019 Jan-Dec;16:1479972318767724. Epub 2018 Apr 9.

Centre de recherche, Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval, Québec, Canada.

Long-term oxygen therapy (LTOT) has beneficial effects on survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia at rest. Two landmark trials suggested that these benefits depend on the time of exposure to oxygen. Patients are usually prescribed LTOT for at least 15-18 hours/day. Read More

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http://dx.doi.org/10.1177/1479972318767724DOI Listing
April 2018
2 Reads

How resources determine pulmonary rehabilitation programs: A survey among Belgian chest physicians.

Chron Respir Dis 2019 Jan-Dec;16:1479972318767732. Epub 2018 Apr 9.

7 CHU-UCL Namur, site Mont-Godinne, Service de Pneumologie, Université catholique de Louvain, Yvoir, Belgium.

Despite overwhelming evidence of its benefits, a widespread implementation of pulmonary rehabilitation (PR) is lacking and the landscape of multidisciplinary programs remains very scattered. The objective of this study is to assess how PR is organized in specialized care centres in Belgium and to identify which barriers may exist according to respiratory physicians. A telephone and online survey was developed by a Belgian expert panel and distributed among all active Belgian chest physicians ( n = 492). Read More

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http://dx.doi.org/10.1177/1479972318767732DOI Listing
April 2018
11 Reads

Asthma knowledge, care, and outcome during pregnancy: The QAKCOP study.

Chron Respir Dis 2019 Jan-Dec;16:1479972318767719. Epub 2018 Apr 5.

3 Department of Obstetrics and Gynecology, St. Josefs Hospital, Wiesbaden, Germany.

Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. Read More

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http://journals.sagepub.com/doi/10.1177/1479972318767719
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http://dx.doi.org/10.1177/1479972318767719DOI Listing
April 2018
9 Reads

Comparative analysis of the psychometric parameters of two quality-of-life questionnaires, the SGRQ and CAT, in the assessment of patients with COPD exacerbations during hospitalization: A multicenter study.

Chron Respir Dis 2018 Nov 12;15(4):374-383. Epub 2018 Mar 12.

3 Hospital Clínic de Barcelona, Barcelona, Spain.

The aim of this study was to assess health-related quality of life (HRQL) in patients with chronic obstructive pulmonary disease (COPD) and to discuss the different tools available for its assessment. The most widely used assessments are the St. George respiratory questionnaire (SGRQ) and the COPD assessment test (CAT) questionnaire. Read More

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http://dx.doi.org/10.1177/1479972318761645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234566PMC
November 2018
6 Reads

High burden of Aspergillus fumigatus infection among chronic respiratory diseases.

Chron Respir Dis 2018 Aug 8;15(3):279-285. Epub 2018 Mar 8.

1 Department of Medicine, Division of Respiratory Medicine and Allergology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.

Aspergillus fumigatus (AF) is a ubiquitous fungus in our environment and causes severe airway disorders. Chronic respiratory diseases (CRDs) are a series of chronic airway and lung diseases. Although both are chronic disorders, however, the relationships between AF and CRDs are still unclear. Read More

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http://dx.doi.org/10.1177/1479972318761654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100170PMC
August 2018
5 Reads

Vitamin D supplementation in adults with bronchiectasis: A pilot study.

Chron Respir Dis 2018 Nov 28;15(4):384-392. Epub 2018 Feb 28.

2 Department of Respiratory Medicine, Middlemore Hospital, Auckland, New Zealand.

Vitamin D supplementation prevents acute respiratory infections and, through modulating innate and adaptive immunity, could have a potential role in bronchiectasis management. The primary aims of this pilot study were to assess serum 25-hydroxyvitamin D (25(OH)D) levels in New Zealand adults with bronchiectasis, and their 25(OH)D levels after vitamin D supplementation. Adults with bronchiectasis received an initial 2. Read More

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http://dx.doi.org/10.1177/1479972318761646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234573PMC
November 2018
8 Reads
2.310 Impact Factor

Elevated circulating ghrelin in patients with COPD: A meta-analysis.

Chron Respir Dis 2018 Nov 27;15(4):365-373. Epub 2018 Feb 27.

2 Department of Respiratory and Critical Care Medicine, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China.

Ghrelin, an endogenous ligand for growth hormone secretagogue receptor, has been implicated in chronic obstructive pulmonary disease (COPD). Recently, several studies reported inconsistent levels of ghrelin in plasma/serum of COPD patients. This meta-analysis aims to determine the circulating level of ghrelin in COPD. Read More

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http://dx.doi.org/10.1177/1479972318757468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234570PMC
November 2018
6 Reads

Predictors of COPD in symptomatic smokers and ex-smokers seen in primary care.

Chron Respir Dis 2018 Nov 27;15(4):393-399. Epub 2018 Feb 27.

1 Department of Pulmonary Medicine, Hvidovre Hospital, Hvidovre, Denmark.

Even in subjects at high risk of chronic obstructive pulmonary disease (COPD), the diagnosis is often missed due to lack of awareness of symptoms and risk factors. The objective of this study was to identify predictors of a diagnosis of COPD in symptomatic current and ex-smokers seen in a primary care setting. General practitioners ( n = 241) consecutively recruited subjects ≥ 35 years, with tobacco exposure, at least one respiratory symptom (i. Read More

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http://dx.doi.org/10.1177/1479972318761655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234571PMC
November 2018
5 Reads

Early versus delayed pulmonary rehabilitation: A randomized controlled trial - Can we do it?

Chron Respir Dis 2018 Aug 22;15(3):323-326. Epub 2018 Feb 22.

1 University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.

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http://dx.doi.org/10.1177/1479972318757469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100167PMC
August 2018
5 Reads

Assessing referral and practice patterns of patients with chronic cough referred for behavioral cough suppression therapy.

Chron Respir Dis 2018 Aug 11;15(3):296-305. Epub 2018 Feb 11.

1 Department of Communicative Sciences and Disorders, University of Montana, Missoula, Montana, USA.

The purpose of this exploratory research was to describe current referral and practice patterns for behavioral cough suppression therapy (BCST) throughout the United States, and to assess the need for improving the efficiency of BCST referral patterns. In study I, 126 speech-language pathologists, who treat patients with refractory chronic cough (RCC) in the United States, completed a survey about referral patterns, cough duration, and patient frustration level. In study II, 36 adults with RCC referred for BCST completed a four-part survey about cough symptoms and treatment. Read More

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http://dx.doi.org/10.1177/1479972318755722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100168PMC
August 2018
2 Reads

Patterns of use, survival and prognostic factors in patients receiving home mechanical ventilation in Western Australia: A single centre historical cohort study.

Chron Respir Dis 2018 Nov 7;15(4):356-364. Epub 2018 Feb 7.

1 Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia.

Home mechanical ventilation (HMV) is used in a wide range of disorders associated with chronic hypoventilation. We describe the patterns of use, survival and predictors of death in Western Australia. We identified 240 consecutive patients (60% male; mean age 58 years and body mass index 31 kg m) referred for HMV between 2005 and 2010. Read More

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http://journals.sagepub.com/doi/10.1177/1479972318755723
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http://dx.doi.org/10.1177/1479972318755723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234575PMC
November 2018
7 Reads

Is there a learning effect when the 6-minute walk test is repeated in people with suspected pulmonary hypertension?

Chron Respir Dis 2018 Nov 23;15(4):339-346. Epub 2018 Jan 23.

4 Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia.

The aim of the study was to determine if there was a difference in 6-minute walk distance (6MWD) when two 6-minute walk tests (6MWTs) were performed at the initial assessment prior to attendance at the pulmonary hypertension (PH) clinic and at the 6-month follow-up. Two 6MWTs were performed at both visits on a 32-m continuous track in the physiotherapy hospital outpatient setting using standard instructions and encouragement. Two hundred and fourteen participants completed two 6MWTs at the initial assessment and 71 participants at the 6-month follow-up (mean (standard deviation) age: 57 (16) years; body mass index: 27 (6) kg/m). Read More

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http://dx.doi.org/10.1177/1479972317752762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234568PMC
November 2018
7 Reads

Frailty: A global measure of the multisystem impact of COPD.

Chron Respir Dis 2018 Nov 16;15(4):347-355. Epub 2018 Jan 16.

1 School of Healthcare Sciences, Cardiff University, University Hospital of Wales, Cardiff, UK.

Chronic obstructive pulmonary disease (COPD) is a multisystem disease that resembles the accumulation of multiple impairments seen in aging. A comprehensive geriatric assessment (CGA) captures multisystem deficits, from which a frailty index (FI) can be derived. We hypothesized that patients with COPD would be frailer than a comparator group free from respiratory disease. Read More

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http://dx.doi.org/10.1177/1479972317752763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234567PMC
November 2018
4 Reads

Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort.

Chron Respir Dis 2018 Nov 12;15(4):329-338. Epub 2017 Dec 12.

1 Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

Cigarette smoking increases the risk of developing both cataract and chronic obstructive pulmonary disease (COPD). The prevalence of cataract and the clinical characteristics of COPD patients with cataract were retrospectively investigated in a 2-year observational COPD cohort. We analyzed 395 patients with complete data on ophthalmologic evaluation (319 subjects with COPD and 76 subjects at risk of COPD). Read More

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http://dx.doi.org/10.1177/1479972317745735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234576PMC
November 2018
20 Reads

Does antibiotic treatment duration affect the outcomes of exacerbations of asthma and COPD? A systematic review.

Chron Respir Dis 2018 Aug 12;15(3):225-240. Epub 2017 Dec 12.

3 Department of Respiratory Medicine, Royal Liverpool University Hospital, Liverpool, UK.

Asthma and chronic obstructive pulmonary disease (COPD) cause significant morbidity and mortality worldwide, primarily through exacerbations. Exacerbations are often treated with antibiotics but their optimal course duration is uncertain. Reducing antibiotic duration may influence antimicrobial resistance but risks treatment failure. Read More

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http://dx.doi.org/10.1177/1479972317745734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100164PMC
August 2018
7 Reads

Dose uniformity of budesonide Easyhaler® under simulated real-life conditions and with low inspiration flow rates.

Chron Respir Dis 2018 Aug 7;15(3):265-271. Epub 2017 Dec 7.

3 Orion Corporation, Orion Pharma, Kuopio, Finland.

Budesonide Easyhaler® multidose dry powder inhaler is approved for the treatment of asthma. Objectives were to determine the delivered dose (DD) uniformity of budesonide Easyhaler® in simulated real-world conditions and with different inspiration flow rates (IFRs). Three dose delivery studies were performed using 100, 200, and 400 µg/dose strengths of budesonide. Read More

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http://dx.doi.org/10.1177/1479972317745733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100165PMC
August 2018
13 Reads

Reluctance of patients with chronic obstructive pulmonary disease in its early stages and their families to participate in a partnership-based self-management trial: A search for explanation.

Chron Respir Dis 2018 Aug 5;15(3):315-322. Epub 2017 Dec 5.

1 Faculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

Recruitment, the process of accessing, screening, selecting and retaining participants for research remains a challenge. In a randomized controlled trial, partnership-based self-management intervention for patients who have chronic obstructive pulmonary disease (COPD) in its initial stages, and their families, a theoretical framework developed for patients with an advanced COPD and their families was modified and implemented in a primary care context. In contrast to recruitment to the original study where 4% decline participation, in this study 25% of the potential patients declined participation. Read More

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http://dx.doi.org/10.1177/1479972317743758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100171PMC
August 2018
9 Reads

Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population.

Chron Respir Dis 2018 Aug 29;15(3):250-257. Epub 2017 Nov 29.

5 Division of Ambulatory Medicine, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Chronic obstructive pulmonary disease (COPD) has been described as a systemic disease. Sarcopenia is one of the systemic effects that is related to several adverse outcomes. The objectives of this study were to estimate the prevalence of sarcopenia and to determine the factors associated with sarcopenia in COPD patients in Southeast Asia. Read More

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http://dx.doi.org/10.1177/1479972317743759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100162PMC
August 2018
7 Reads

Daily spirometry in an acute exacerbation of adult cystic fibrosis patients.

Chron Respir Dis 2018 Aug 28;15(3):258-264. Epub 2017 Nov 28.

3 Division of Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA, USA.

To help answer the question of length of intravenous antibiotics during an acute exacerbation of cystic fibrosis (CF), we had subjects to follow daily home spirometry while on intravenous antibiotics. CF patients, 18 and older, with an acute exacerbation requiring intravenous antibiotics had a daily FEV1. The average time to a 10% increase over their initial sick FEV1 was calculated, as well as the time to a new baseline. Read More

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http://dx.doi.org/10.1177/1479972317743756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100161PMC
August 2018
6 Reads

Clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease.

Chron Respir Dis 2018 Aug 23;15(3):306-314. Epub 2017 Nov 23.

1 Department of Pulmonology, Yedikule Chest Disease and Thoracic Surgery Training Hospital, University of Health Sciences, İstanbul, Turkey.

The aim of this study was to evaluate the clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease (COPD). A total of 91 patients with stable moderate to very severe COPD were included in this study. Cognitive functions of the patients were evaluated using the mini-mental state examination (MMSE) tool and clock-drawing test. Read More

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http://dx.doi.org/10.1177/1479972317743757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100172PMC
August 2018
17 Reads

What kind of information and communication technologies do patients with COPD prefer to use? A cross-sectional study in Latin America.

Chron Respir Dis 2018 Aug 19;15(3):286-295. Epub 2017 Nov 19.

5 Centro de Investigación en Salud Pública y Epidemiología Clínica, Universidad Tecnológica Equinoccial, Quito, Ecuador.

The aim of the present study was to assess the frequency of uses and preferences of information and communication technologies (ICTs) among Latin American chronic obstructive pulmonary disease (COPD) patients. We conducted an anonymous cross-sectional survey study on Latin American COPD patients. The adapted version of the Michigan questionnaire was employed in eligible outpatients in different cities of Latin America. Read More

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http://dx.doi.org/10.1177/1479972317741895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100163PMC
August 2018
5 Reads

Relationship between lung function and inhalation devices for LAMA/LABA therapy for chronic obstructive pulmonary disease.

Chron Respir Dis 2018 Nov 19;15(4):419-420. Epub 2017 Nov 19.

2 Department of Pulmonology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan.

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http://dx.doi.org/10.1177/1479972317741897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234572PMC
November 2018
4 Reads

Correlation between heart size and emphysema in patients with chronic obstructive pulmonary disease: CT-based analysis using inspiratory and expiratory scans.

Chron Respir Dis 2018 Aug 15;15(3):272-278. Epub 2017 Nov 15.

1 Department of Radiology, St. Marianna University School of Medicine, Kawasaki, Kanagawa Prefecture, Japan.

The objective of this study was to investigate the relationship between the extent of emphysema and heart size in patients with chronic obstructive pulmonary disease (COPD) using inspiratory and expiratory chest computed tomography (CT). This retrospective study was approved by the institutional review board and informed consent was waived. We measured lung volume (LV), low attenuation area percent (%LAA; less than or equal to -950 HU), maximum cardiac area, and maximum transverse cardiac diameter on inspiratory/expiratory chest CT in 60 patients with COPD. Read More

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http://dx.doi.org/10.1177/1479972317741896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100166PMC
August 2018
16 Reads

Inflammatory biomarkers and radiologic measurements in never-smokers with COPD: A cross-sectional study from the CODA cohort.

Chron Respir Dis 2018 May 8;15(2):138-145. Epub 2017 Nov 8.

1 Samsung Medical Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Various biomarkers have emerged as potential surrogates to represent various subgroups of chronic obstructive pulmonary disease (COPD), which manifest with different phenotypes. However, the biomarkers representing never-smokers with COPD have not yet been well elucidated. The aim of this study was to evaluate the associations of certain serum and radiological biomarkers with the presence of COPD in never-smokers. Read More

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http://dx.doi.org/10.1177/1479972317736293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958470PMC
May 2018
21 Reads
1 Citation
2.310 Impact Factor

Obesity and metabolic syndrome in COPD: Is exercise the answer?

Chron Respir Dis 2018 May 8;15(2):173-181. Epub 2017 Nov 8.

2 National Centre for Sport and Exercise Medicine, School of Sport Exercise and Health Sciences, Loughborough University, Loughborough, UK.

Approximately half of all patients with chronic obstructive pulmonary disease (COPD) attending pulmonary rehabilitation (PR) programmes are overweight or obese which negatively impacts upon dyspnoea and exercise tolerance particularly when walking. Within the obese population (without COPD), the observed heterogeneity in prognosis is in part explained by the variability in the risk of developing cardiovascular disease or diabetes (cardiometabolic risk) leading to the description of metabolic syndrome. In obesity alone, high-intensity aerobic training can support healthy weight loss and improve the constituent components of metabolic syndrome. Read More

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http://dx.doi.org/10.1177/1479972317736294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958471PMC
May 2018
9 Reads

Effects of varenicline therapy in combination with advanced behavioral support on smoking cessation and quality of life in inpatients with acute exacerbation of COPD, bronchial asthma, or community-acquired pneumonia: A prospective, open-label, preference-based, 52-week, follow-up trial.

Chron Respir Dis 2018 May 8;15(2):146-156. Epub 2017 Nov 8.

3 Department of Physiology, Medical School, University of Thessaly, Larissa, Greece.

Quitting smoking is the most important element in the therapeutic management of chronic respiratory diseases. Combining pharmacotherapy with behavioral support increases smoking cessation success rates. In addition, hospitalized smokers have increased motivation to quit. Read More

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http://dx.doi.org/10.1177/1479972317740128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958473PMC
May 2018
10 Reads