542 results match your criteria Chronic Respiratory Disease[Journal]


The influence of South Asian ethnicity on the incremental shuttle walk test in UK adults.

Chron Respir Dis 2018 Jan 1:1479972318785832. Epub 2018 Jan 1.

1 Centre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre - Respiratory, NIHR Institute of Lung Health, Leicester, UK.

The objective of this study was to compare incremental shuttle walking test (ISWT) performance between South Asian and Caucasian British adults, identify predictors of ISWT distance and produce ethnicity-specific reference equations. Data from a mixed gender sample aged 40-75 years from Leicestershire, United Kingdom, were selected for analyses. Analysis of covariance determined differences in ISWT performance between South Asian and Caucasian British ethnic groups. Read More

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January 2018
2 Reads

Comparison of procalcitonin, C-reactive protein, white blood cell count and clinical status in diagnosing pneumonia in patients hospitalized with acute exacerbations of COPD: A prospective observational study.

Chron Respir Dis 2018 Jan 1:1479972318769762. Epub 2018 Jan 1.

4 Department of Clinical Chemistry, Trondheim University Hospital, Trondheim, Norway.

Lower respiratory tract infection is the most common cause of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of the present study was to compare the accuracy of procalcitonin (PCT), C-reactive protein (CRP) and white blood cell count (WBC) as single diagnostic tests and in combination with clinical signs and symptoms to diagnose pneumonia in patients hospitalized with AECOPD. This was a prospective, single centre observational study. Read More

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January 2018

Depression is a major determinant of both disease-specific and generic health-related quality of life in people with severe COPD.

Chron Respir Dis 2018 Jan 1:1479972318775422. Epub 2018 Jan 1.

1 Department of Internal Medicine, School of Medicine, Pusan National University, Busan, Republic of Korea.

The quality of life of patients with chronic obstructive pulmonary disease (COPD) decreases significantly as the disease progresses; those with severe COPD are affected most. This article investigates predictors of the disease-specific and generic health-related quality of life (HRQL) in patients with severe COPD. This multicentre prospective cross-sectional study enrolled 80 patients with severe COPD. Read More

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January 2018
1 Read

Relationship of spirometric, body plethysmographic, and diffusing capacity parameters to emphysema scores derived from CT scans.

Chron Respir Dis 2018 Jan 1:1479972318775423. Epub 2018 Jan 1.

10 Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Comprehensive Pneumology Center Munich (CPC-M), Ludwig-Maximilians-Universität München, Munich, Germany.

Phenotyping of chronic obstructive pulmonary disease (COPD) with computed tomography (CT) is used to distinguish between emphysema- and airway-dominated type. The phenotype is reflected in correlations with lung function measures. Among these, the relative value of body plethysmography has not been quantified. Read More

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January 2018

Feasibility study to assess the effect of a brief mindfulness intervention for patients with chronic obstructive pulmonary disease: A randomized controlled trial.

Chron Respir Dis 2018 Jan 1:1479972318766140. Epub 2018 Jan 1.

2 Population Health Research Institute, St George's, University of London, London, UK.

Psychological distress is common among patients with chronic obstructive pulmonary disease (COPD). This study aimed to assess whether a 10-minute mindfulness intervention reduces distress and breathlessness, improves mood and increases mindfulness among hospital inpatients following acute exacerbation of COPD.Fifty patients were recruited following an acute admission. Read More

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January 2018

Why are COPD patients unable to complete the outpatient pulmonary rehabilitation program?

Chron Respir Dis 2018 Jan 1:1479972318767206. Epub 2018 Jan 1.

2 Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey.

This study aims to compare demographic and clinical characteristics of chronic obstructive pulmonary disease (COPD) patients who complete and fail to complete outpatient pulmonary rehabilitation (PR) program and to determine the reasons for not completing the program. Patients with COPD referred to the PR program were divided into two groups: Those who completed the program were classified as group 1 and those who did not complete were classified as group 2, and their data were compared. Patients who failed to complete the program were contacted through phone and asked why they ceased their participation in the program. Read More

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January 2018
1 Read

Chronic bronchitis: High prevalence in never smokers and underdiagnosis- A population-based study in Colombia.

Chron Respir Dis 2018 Jan 1:1479972318769771. Epub 2018 Jan 1.

1 Research Department, Fundacion Neumologica Colombiana, Bogota, Colombia.

The objective of the article was to establish the prevalence, underdiagnosis, and risk factors of chronic bronchitis (CB) in a general population in five Colombian cities. Cross-sectional study using a probabilistic sampling technique in five Colombian cities was adopted. The CB definition was "cough and expectoration for three or more months per year for at least two consecutive years. Read More

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January 2018
1 Read

Prospective risk of osteoporotic fractures in patients with advanced chronic obstructive pulmonary disease.

Chron Respir Dis 2018 Jan 1:1479972318769763. Epub 2018 Jan 1.

1 Institute for Lung Health, NIHR Leicester Biomedical Research Centre - Respiratory, UHL, Leicester, UK.

Despite the high prevalence of osteoporosis in chronic obstructive pulmonary disease (COPD) patients, the fracture risk prediction tools are not routinely undertaken in the management of COPD. We quantified fracture risk using a validated risk prediction tool (Fracture Risk Assessment (FRAX®)) and determined potential bone-protection treatment needs in patients with advanced COPD. The 10-year probability of major osteoporotic or hip fracture was calculated using the FRAX tool in a cohort of patients attending a hospital complex COPD service. Read More

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January 2018
1 Read

Adherence to long-term oxygen therapy in patients with chronic obstructive pulmonary disease.

Chron Respir Dis 2018 Jan 1:1479972318767724. Epub 2018 Jan 1.

Centre de recherche, Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval, Québec, Canada.

Long-term oxygen therapy (LTOT) has beneficial effects on survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia at rest. Two landmark trials suggested that these benefits depend on the time of exposure to oxygen. Patients are usually prescribed LTOT for at least 15-18 hours/day. Read More

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January 2018
1 Read

How resources determine pulmonary rehabilitation programs: A survey among Belgian chest physicians.

Chron Respir Dis 2018 Jan 1:1479972318767732. Epub 2018 Jan 1.

7 CHU-UCL Namur, site Mont-Godinne, Service de Pneumologie, Université catholique de Louvain, Yvoir, Belgium.

Despite overwhelming evidence of its benefits, a widespread implementation of pulmonary rehabilitation (PR) is lacking and the landscape of multidisciplinary programs remains very scattered. The objective of this study is to assess how PR is organized in specialized care centres in Belgium and to identify which barriers may exist according to respiratory physicians. A telephone and online survey was developed by a Belgian expert panel and distributed among all active Belgian chest physicians ( n = 492). Read More

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January 2018
8 Reads

Asthma knowledge, care, and outcome during pregnancy: The QAKCOP study.

Chron Respir Dis 2018 Jan 1:1479972318767719. Epub 2018 Jan 1.

3 Department of Obstetrics and Gynecology, St. Josefs Hospital, Wiesbaden, Germany.

Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. Read More

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January 2018
2 Reads

Comparative analysis of the psychometric parameters of two quality-of-life questionnaires, the SGRQ and CAT, in the assessment of patients with COPD exacerbations during hospitalization: A multicenter study.

Chron Respir Dis 2018 Jan 1:1479972318761645. Epub 2018 Jan 1.

3 Hospital Clínic de Barcelona, Barcelona, Spain.

The aim of this study was to assess health-related quality of life (HRQL) in patients with chronic obstructive pulmonary disease (COPD) and to discuss the different tools available for its assessment. The most widely used assessments are the St. George respiratory questionnaire (SGRQ) and the COPD assessment test (CAT) questionnaire. Read More

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January 2018
3 Reads

High burden of Aspergillus fumigatus infection among chronic respiratory diseases.

Chron Respir Dis 2018 Jan 1:1479972318761654. Epub 2018 Jan 1.

1 Department of Medicine, Division of Respiratory Medicine and Allergology, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.

Aspergillus fumigatus (AF) is a ubiquitous fungus in our environment and causes severe airway disorders. Chronic respiratory diseases (CRDs) are a series of chronic airway and lung diseases. Although both are chronic disorders, however, the relationships between AF and CRDs are still unclear. Read More

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January 2018
2 Reads

Vitamin D supplementation in adults with bronchiectasis: A pilot study.

Chron Respir Dis 2018 Jan 1:1479972318761646. Epub 2018 Jan 1.

2 Department of Respiratory Medicine, Middlemore Hospital, Auckland, New Zealand.

Vitamin D supplementation prevents acute respiratory infections and, through modulating innate and adaptive immunity, could have a potential role in bronchiectasis management. The primary aims of this pilot study were to assess serum 25-hydroxyvitamin D (25(OH)D) levels in New Zealand adults with bronchiectasis, and their 25(OH)D levels after vitamin D supplementation. Adults with bronchiectasis received an initial 2. Read More

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January 2018
3 Reads

Elevated circulating ghrelin in patients with COPD: A meta-analysis.

Chron Respir Dis 2018 Jan 1:1479972318757468. Epub 2018 Jan 1.

2 Department of Respiratory and Critical Care Medicine, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China.

Ghrelin, an endogenous ligand for growth hormone secretagogue receptor, has been implicated in chronic obstructive pulmonary disease (COPD). Recently, several studies reported inconsistent levels of ghrelin in plasma/serum of COPD patients. This meta-analysis aims to determine the circulating level of ghrelin in COPD. Read More

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January 2018
4 Reads

Predictors of COPD in symptomatic smokers and ex-smokers seen in primary care.

Chron Respir Dis 2018 Jan 1:1479972318761655. Epub 2018 Jan 1.

1 Department of Pulmonary Medicine, Hvidovre Hospital, Hvidovre, Denmark.

Even in subjects at high risk of chronic obstructive pulmonary disease (COPD), the diagnosis is often missed due to lack of awareness of symptoms and risk factors. The objective of this study was to identify predictors of a diagnosis of COPD in symptomatic current and ex-smokers seen in a primary care setting. General practitioners ( n = 241) consecutively recruited subjects ≥ 35 years, with tobacco exposure, at least one respiratory symptom (i. Read More

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January 2018
3 Reads

Early versus delayed pulmonary rehabilitation: A randomized controlled trial - Can we do it?

Chron Respir Dis 2018 Jan 1:1479972318757469. Epub 2018 Jan 1.

1 University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.

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January 2018
2 Reads

Assessing referral and practice patterns of patients with chronic cough referred for behavioral cough suppression therapy.

Chron Respir Dis 2018 Jan 1:1479972318755722. Epub 2018 Jan 1.

1 Department of Communicative Sciences and Disorders, University of Montana, Missoula, Montana, USA.

The purpose of this exploratory research was to describe current referral and practice patterns for behavioral cough suppression therapy (BCST) throughout the United States, and to assess the need for improving the efficiency of BCST referral patterns. In study I, 126 speech-language pathologists, who treat patients with refractory chronic cough (RCC) in the United States, completed a survey about referral patterns, cough duration, and patient frustration level. In study II, 36 adults with RCC referred for BCST completed a four-part survey about cough symptoms and treatment. Read More

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January 2018
1 Read

Patterns of use, survival and prognostic factors in patients receiving home mechanical ventilation in Western Australia: A single centre historical cohort study.

Chron Respir Dis 2018 Jan 1:1479972318755723. Epub 2018 Jan 1.

1 Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia.

Home mechanical ventilation (HMV) is used in a wide range of disorders associated with chronic hypoventilation. We describe the patterns of use, survival and predictors of death in Western Australia. We identified 240 consecutive patients (60% male; mean age 58 years and body mass index 31 kg m) referred for HMV between 2005 and 2010. Read More

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January 2018
2 Reads

Is there a learning effect when the 6-minute walk test is repeated in people with suspected pulmonary hypertension?

Chron Respir Dis 2018 Jan 1:1479972317752762. Epub 2018 Jan 1.

4 Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia.

The aim of the study was to determine if there was a difference in 6-minute walk distance (6MWD) when two 6-minute walk tests (6MWTs) were performed at the initial assessment prior to attendance at the pulmonary hypertension (PH) clinic and at the 6-month follow-up. Two 6MWTs were performed at both visits on a 32-m continuous track in the physiotherapy hospital outpatient setting using standard instructions and encouragement. Two hundred and fourteen participants completed two 6MWTs at the initial assessment and 71 participants at the 6-month follow-up (mean (standard deviation) age: 57 (16) years; body mass index: 27 (6) kg/m). Read More

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January 2018
5 Reads

Frailty: A global measure of the multisystem impact of COPD.

Chron Respir Dis 2018 Jan 1:1479972317752763. Epub 2018 Jan 1.

1 School of Healthcare Sciences, Cardiff University, University Hospital of Wales, Cardiff, UK.

Chronic obstructive pulmonary disease (COPD) is a multisystem disease that resembles the accumulation of multiple impairments seen in aging. A comprehensive geriatric assessment (CGA) captures multisystem deficits, from which a frailty index (FI) can be derived. We hypothesized that patients with COPD would be frailer than a comparator group free from respiratory disease. Read More

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January 2018
2 Reads

Impact of cataract on health-related quality of life in a longitudinal Japanese chronic obstructive pulmonary cohort.

Chron Respir Dis 2017 Jan 1:1479972317745735. Epub 2017 Jan 1.

1 Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

Cigarette smoking increases the risk of developing both cataract and chronic obstructive pulmonary disease (COPD). The prevalence of cataract and the clinical characteristics of COPD patients with cataract were retrospectively investigated in a 2-year observational COPD cohort. We analyzed 395 patients with complete data on ophthalmologic evaluation (319 subjects with COPD and 76 subjects at risk of COPD). Read More

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January 2017
7 Reads

Does antibiotic treatment duration affect the outcomes of exacerbations of asthma and COPD? A systematic review.

Chron Respir Dis 2017 Jan 1:1479972317745734. Epub 2017 Jan 1.

3 Department of Respiratory Medicine, Royal Liverpool University Hospital, Liverpool, UK.

Asthma and chronic obstructive pulmonary disease (COPD) cause significant morbidity and mortality worldwide, primarily through exacerbations. Exacerbations are often treated with antibiotics but their optimal course duration is uncertain. Reducing antibiotic duration may influence antimicrobial resistance but risks treatment failure. Read More

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January 2017
5 Reads

Dose uniformity of budesonide Easyhaler® under simulated real-life conditions and with low inspiration flow rates.

Chron Respir Dis 2017 Jan 1:1479972317745733. Epub 2017 Jan 1.

3 Orion Corporation, Orion Pharma, Kuopio, Finland.

Budesonide Easyhaler® multidose dry powder inhaler is approved for the treatment of asthma. Objectives were to determine the delivered dose (DD) uniformity of budesonide Easyhaler® in simulated real-world conditions and with different inspiration flow rates (IFRs). Three dose delivery studies were performed using 100, 200, and 400 µg/dose strengths of budesonide. Read More

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January 2017
6 Reads

Reluctance of patients with chronic obstructive pulmonary disease in its early stages and their families to participate in a partnership-based self-management trial: A search for explanation.

Chron Respir Dis 2017 Jan 1:1479972317743758. Epub 2017 Jan 1.

1 Faculty of Nursing, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

Recruitment, the process of accessing, screening, selecting and retaining participants for research remains a challenge. In a randomized controlled trial, partnership-based self-management intervention for patients who have chronic obstructive pulmonary disease (COPD) in its initial stages, and their families, a theoretical framework developed for patients with an advanced COPD and their families was modified and implemented in a primary care context. In contrast to recruitment to the original study where 4% decline participation, in this study 25% of the potential patients declined participation. Read More

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January 2017
3 Reads

Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population.

Chron Respir Dis 2017 Jan 1:1479972317743759. Epub 2017 Jan 1.

5 Division of Ambulatory Medicine, Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Chronic obstructive pulmonary disease (COPD) has been described as a systemic disease. Sarcopenia is one of the systemic effects that is related to several adverse outcomes. The objectives of this study were to estimate the prevalence of sarcopenia and to determine the factors associated with sarcopenia in COPD patients in Southeast Asia. Read More

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January 2017
3 Reads

Daily spirometry in an acute exacerbation of adult cystic fibrosis patients.

Chron Respir Dis 2017 Jan 1:1479972317743756. Epub 2017 Jan 1.

3 Division of Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA, USA.

To help answer the question of length of intravenous antibiotics during an acute exacerbation of cystic fibrosis (CF), we had subjects to follow daily home spirometry while on intravenous antibiotics. CF patients, 18 and older, with an acute exacerbation requiring intravenous antibiotics had a daily FEV1. The average time to a 10% increase over their initial sick FEV1 was calculated, as well as the time to a new baseline. Read More

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January 2017
3 Reads

Clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease.

Chron Respir Dis 2017 Jan 1:1479972317743757. Epub 2017 Jan 1.

1 Department of Pulmonology, Yedikule Chest Disease and Thoracic Surgery Training Hospital, University of Health Sciences, İstanbul, Turkey.

The aim of this study was to evaluate the clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease (COPD). A total of 91 patients with stable moderate to very severe COPD were included in this study. Cognitive functions of the patients were evaluated using the mini-mental state examination (MMSE) tool and clock-drawing test. Read More

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January 2017
10 Reads

What kind of information and communication technologies do patients with COPD prefer to use? A cross-sectional study in Latin America.

Chron Respir Dis 2017 Jan 1:1479972317741895. Epub 2017 Jan 1.

5 Centro de Investigación en Salud Pública y Epidemiología Clínica, Universidad Tecnológica Equinoccial, Quito, Ecuador.

The aim of the present study was to assess the frequency of uses and preferences of information and communication technologies (ICTs) among Latin American chronic obstructive pulmonary disease (COPD) patients. We conducted an anonymous cross-sectional survey study on Latin American COPD patients. The adapted version of the Michigan questionnaire was employed in eligible outpatients in different cities of Latin America. Read More

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January 2017
3 Reads

Relationship between lung function and inhalation devices for LAMA/LABA therapy for chronic obstructive pulmonary disease.

Chron Respir Dis 2017 Jan 1:1479972317741897. Epub 2017 Jan 1.

2 Department of Pulmonology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan.

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January 2017
2 Reads

Correlation between heart size and emphysema in patients with chronic obstructive pulmonary disease: CT-based analysis using inspiratory and expiratory scans.

Chron Respir Dis 2017 Jan 1:1479972317741896. Epub 2017 Jan 1.

1 Department of Radiology, St. Marianna University School of Medicine, Kawasaki, Kanagawa Prefecture, Japan.

The objective of this study was to investigate the relationship between the extent of emphysema and heart size in patients with chronic obstructive pulmonary disease (COPD) using inspiratory and expiratory chest computed tomography (CT). This retrospective study was approved by the institutional review board and informed consent was waived. We measured lung volume (LV), low attenuation area percent (%LAA; less than or equal to -950 HU), maximum cardiac area, and maximum transverse cardiac diameter on inspiratory/expiratory chest CT in 60 patients with COPD. Read More

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January 2017
3 Reads

Inflammatory biomarkers and radiologic measurements in never-smokers with COPD: A cross-sectional study from the CODA cohort.

Chron Respir Dis 2018 May 8;15(2):138-145. Epub 2017 Nov 8.

1 Samsung Medical Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Various biomarkers have emerged as potential surrogates to represent various subgroups of chronic obstructive pulmonary disease (COPD), which manifest with different phenotypes. However, the biomarkers representing never-smokers with COPD have not yet been well elucidated. The aim of this study was to evaluate the associations of certain serum and radiological biomarkers with the presence of COPD in never-smokers. Read More

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May 2018
7 Reads

Obesity and metabolic syndrome in COPD: Is exercise the answer?

Chron Respir Dis 2018 May 8;15(2):173-181. Epub 2017 Nov 8.

2 National Centre for Sport and Exercise Medicine, School of Sport Exercise and Health Sciences, Loughborough University, Loughborough, UK.

Approximately half of all patients with chronic obstructive pulmonary disease (COPD) attending pulmonary rehabilitation (PR) programmes are overweight or obese which negatively impacts upon dyspnoea and exercise tolerance particularly when walking. Within the obese population (without COPD), the observed heterogeneity in prognosis is in part explained by the variability in the risk of developing cardiovascular disease or diabetes (cardiometabolic risk) leading to the description of metabolic syndrome. In obesity alone, high-intensity aerobic training can support healthy weight loss and improve the constituent components of metabolic syndrome. Read More

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May 2018
4 Reads

Effects of varenicline therapy in combination with advanced behavioral support on smoking cessation and quality of life in inpatients with acute exacerbation of COPD, bronchial asthma, or community-acquired pneumonia: A prospective, open-label, preference-based, 52-week, follow-up trial.

Chron Respir Dis 2018 May 8;15(2):146-156. Epub 2017 Nov 8.

3 Department of Physiology, Medical School, University of Thessaly, Larissa, Greece.

Quitting smoking is the most important element in the therapeutic management of chronic respiratory diseases. Combining pharmacotherapy with behavioral support increases smoking cessation success rates. In addition, hospitalized smokers have increased motivation to quit. Read More

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May 2018
4 Reads

High-sensitivity cardiac troponin T in obstructive sleep apnea patients without cardiovascular diseases: Efficacy of CPAP treatment.

Chron Respir Dis 2018 May 8;15(2):157-164. Epub 2017 Nov 8.

1 Department of Respiratory Medicine, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China.

The aims of this article were to determine the levels of serum high-sensitivity cardiac troponin T (hs-cTnT) in obstructive sleep apnea (OSA) patients without cardiovascular disease (CVD) and to assess the efficacy of continuous positive airway pressure (CPAP). Snorers referred for polysomnography (PSG) for the investigation of OSA were eligible and hs-cTnT levels measured in our pilot study. Hs-cTnT was measured again after 3 months of CPAP treatment in participants with severe OSA. Read More

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May 2018
7 Reads

COPD in exclusive narghile smokers: Some points to verify.

Authors:
Helmi Ben Saad

Chron Respir Dis 2017 11;14(4):420-421

Research Laboratory N° LR14ES05: Interactions of the Cardiopulmonary System, Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia.

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November 2017
3 Reads

Bacterial infections in patients with primary ciliary dyskinesia: Comparison with cystic fibrosis.

Chron Respir Dis 2017 Nov 6;14(4):392-406. Epub 2017 Mar 6.

1 Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Primary ciliary dyskinesia (PCD) is an autosomal recessive disorder associated with severely impaired mucociliary clearance caused by defects in ciliary structure and function. Although recurrent bacterial infection of the respiratory tract is one of the major clinical features of this disease, PCD airway microbiology is understudied. Despite the differences in pathophysiology, assumptions about respiratory tract infections in patients with PCD are often extrapolated from cystic fibrosis (CF) airway microbiology. Read More

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November 2017
3 Reads

Health status of COPD patients undergoing pulmonary rehabilitation: A comparative responsiveness of the CAT and SGRQ.

Chron Respir Dis 2017 Nov 15;14(4):352-359. Epub 2017 Mar 15.

5 Department of Medicine, Faculty of Medicine and Surgery; University of Malta, Msida, Malta.

The St. George's Respiratory Questionnaire (SGRQ) and chronic obstructive pulmonary disease (COPD) assessment test (CAT) are the measures used to assess health status. This study aims to examine the responsiveness of these tools by severity of dyspnoea category in patients with COPD. Read More

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November 2017
5 Reads

New models of care for respiratory disease: A thematic edition.

Chron Respir Dis 2018 Feb 5;15(1):3-4. Epub 2017 Oct 5.

4 Canadian Foundation for Healthcare Improvement, Ottawa, Ontario, Canada.

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February 2018
5 Reads

Authors' response to letter-COPD in exclusive narghile smokers: Some points to verify.

Chron Respir Dis 2017 Nov 2;14(4):422. Epub 2017 Oct 2.

1 Department of Internal Medicine, Shohadaye Khalije Fars Hospital, Bushehr University of Medical Sciences, Bushehr, Iran.

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November 2017
2 Reads

Home-based pulmonary rehabilitation for people with COPD: A qualitative study reporting the patient perspective.

Chron Respir Dis 2018 May 4;15(2):123-130. Epub 2017 Sep 4.

1 Department of Physiotherapy, La Trobe University, Melbourne, VIC, Australia.

This study aimed to document the perspective of patients with chronic obstructive pulmonary disease (COPD) who underwent home-based pulmonary rehabilitation (HBPR) in a clinical trial. In this qualitative study, open-ended questions explored participants' views regarding HBPR. Thirteen semi-structured interviews were analysed using a thematic analysis approach. Read More

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May 2018
6 Reads

Shuttle walk tests in people with COPD who demonstrate exercise-induced oxygen desaturation: An analysis of test repeatability and cardiorespiratory responses.

Chron Respir Dis 2018 May 30;15(2):131-137. Epub 2017 Aug 30.

1 Discipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, Lidcombe, New South Wales, Australia.

Exercise-induced oxygen desaturation (EID) is prevalent in people with chronic obstructive pulmonary disease (COPD). This article reports a sub-analysis from a randomized controlled trial (RCT) in people with COPD and EID (COPD/EID). The primary aim, in people with COPD/ EID, was to determine the repeatability of the distance and time walked in the incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT), respectively. Read More

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May 2018
6 Reads

Telehealth pulmonary rehabilitation: A review of the literature and an example of a nationwide initiative to improve the accessibility of pulmonary rehabilitation.

Chron Respir Dis 2018 Feb 8;15(1):41-47. Epub 2017 Aug 8.

1 Department of Medicine, Faculty of Medicine, University of Alberta, Edmonton, Canada.

Several different applications of telehealth technologies have been used in the care of respiratory patients, including telemonitoring, teleconsultations, tele-education, and telehealth-pulmonary rehabilitation (PR). Telehealth technology provides an opportunity to assist in the management of chronic respiratory diseases and improve access to PR programs. While there is inconclusive evidence as to the effectiveness of telemonitoring to reduce healthcare utilization and detection of exacerbations, teleconsultations have been shown to be an effective means to assess patients' disease prior to the initiation of PR, and telehealth PR has been shown to be as effective as institution-based PR at improving functional exercise capacity and health-related quality of life. Read More

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February 2018
9 Reads

How do patients conceptualize chronic obstructive pulmonary disease?

Chron Respir Dis 2017 Aug 19;14(3):245-255. Epub 2016 Dec 19.

1 Department of Family Medicine, Alpert Medical School of Brown University, Providence, RI, USA.

Chronic obstructive pulmonary disease (COPD) is a leading cause of death in the United States, yet even at risk or diagnosed patients misunderstand COPD and its consequences for their quality of life and mortality. This study explored how patients conceptualize the causes, symptoms, consequences, treatment, and risk for developing COPD. The study consisted of six focus groups: 39 participants who were adults > 40 and current smoker or have COPD symptoms, family history, or exposures. Read More

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August 2017
3 Reads

Effect of respiratory rehabilitation techniques on the autonomic function in patients with chronic obstructive pulmonary disease: A systematic review.

Chron Respir Dis 2017 Aug 15;14(3):217-230. Epub 2016 Dec 15.

1 Department of Rehabilitation Sciences and Physiotherapy, Ghent University, Belgium.

Patients with chronic obstructive pulmonary disease (COPD) show several extrapulmonary abnormalities such as impairment in the autonomic function (AF). Similarly, the use of respiratory training techniques such as controlled breathing techniques, noninvasive mechanical ventilation (NIMV), and oxygen supplementation for AF modulation in patients with COPD is popular in existing literature. However, the evidence to support their use is nonexistent. Read More

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August 2017
6 Reads

APACHE II score cannot predict successful weaning from prolonged mechanical ventilation.

Chron Respir Dis 2017 Aug 24;14(3):270-275. Epub 2017 Feb 24.

3 Department of Anaesthesiology and Intensive Care, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

At least 5% of all intensive care unit patients require prolonged respiratory support. Multiple factors have been suggested as possible predictors of successful respiratory weaning so far. We sought to verify whether the Acute Physiology and Chronic Health Evaluation II (APACHE II) can predict freedom from prolonged mechanical ventilation (PMV) in patients treated in a regional weaning centre. Read More

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August 2017
4 Reads

Validity and reliability of strain gauge measurement of volitional quadriceps force in patients with COPD.

Chron Respir Dis 2017 Aug 24;14(3):289-297. Epub 2017 Feb 24.

1 Department of Rehabilitation Sciences, KU Leuven-University of Leuven, Leuven, Belgium.

This study investigated the validity and reliability of fixed strain gauge measurements of isometric quadriceps force in patients with chronic obstructive pulmonary disease (COPD). A total cohort of 138 patients with COPD were assessed. To determine validity, maximal volitional quadriceps force was evaluated during isometric maximal voluntary contraction (MVC) manoeuvre via a fixed strain gauge dynamometer and compared to (a) potentiated non-volitional quadriceps force obtained via magnetic stimulation of the femoral nerve (twitch (Tw); n = 92) and (b) volitional computerized dynamometry (Biodex; n = 46) and analysed via correlation coefficients. Read More

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August 2017
3 Reads

Physical activity, sedentary behaviour and sleep in COPD guidelines: A systematic review.

Chron Respir Dis 2017 Aug 24;14(3):231-244. Epub 2017 Feb 24.

1 Alliance for Research in Exercise, Nutrition and Activity, School of Health Sciences, University of South Australia, Adelaide, South Australia, Australia.

Objectives: Physical activity, sedentary and sleep behaviours have strong associations with health. This systematic review aimed to identify how clinical practice guidelines (CPGs) for the management of chronic obstructive pulmonary disease (COPD) report specific recommendations and strategies for these movement behaviours.

Methods: A systematic search of databases (Medline, Scopus, CiNAHL, EMbase, Clinical Guideline), reference lists and websites identified current versions of CPGs published since 2005. Read More

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August 2017
3 Reads

Patterns of use of dry powder inhalers versus pressurized metered-dose inhalers devices in adult patients with chronic obstructive pulmonary disease or asthma: An observational comparative study.

Chron Respir Dis 2017 Aug 24;14(3):309-320. Epub 2017 Feb 24.

2 School of Pharmacy, Lebanese American University, Byblos, Lebanon.

Numerous patients with chronic obstructive pulmonary disease (COPD) and asthma do not use inhaler devices properly, which can contribute to poor disease control. The objective of this study is to assess the technical and safety use of dry powder inhalers (DPIs) versus pressurized metered-dose inhalers (MDIs) in adult patients with COPD or asthma in Lebanon. A concurrent, prospective comparative observational study was conducted at one hospital and 15 community pharmacies in Lebanon. Read More

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August 2017
3 Reads

Clinical-effectiveness of self-management interventions in chronic obstructive pulmonary disease: An overview of reviews.

Chron Respir Dis 2017 Aug 24;14(3):276-288. Epub 2017 Feb 24.

1 Health Technology Assessment, Health Information and Quality Authority, Dublin, Ireland.

Self-management (SM) is defined as the provision of interventions to increase patients' skills and confidence, empowering the individual to take an active part in their disease management. There is uncertainty regarding the optimal format and the short- and long-term benefits of chronic obstructive pulmonary disease (COPD) SM interventions in adults. Therefore, a high-quality overview of reviews was updated to examine their clinical effectiveness. Read More

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August 2017
3 Reads