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Curr Opin Obstet Gynecol 2020 Jun 1. Epub 2020 Jun 1.

Creighton University, St. Joseph's Hospital & Medical Center, Creighton University School of Medicine, Phoenix, Arizona, USA.

Purpose Of Review: The purpose of this publication is to review the currently available and most up-to-date information regarding the pathogenesis, diagnosis, and treatment of pelvic congestion syndrome.

Recent Findings: The diagnosis of pelvic congestion syndrome is difficult to make; however, it should remain on the differential for chronic pelvic pain. The most recent available research seems to favour endovascular treatment with interventional radiology over surgical management, with high success rate and low occurrence of complications. Read More

Int J Mol Sci 2020 May 31;21(11). Epub 2020 May 31.

Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 613016, Taiwan.

Non-bacterial prostatitis is an inflammatory disease that is difficult to treat. Oligonucleotide aptamers are well known for their stability and flexibility in conjugating various inflammatory molecules. In this study, we investigated the effects of inflammatory cytokine-targeting aptamers (ICTA), putative neutralizers of TNF-alpha and IL-1 beta activation, on local carrageenan-induced prostate inflammation, allodynia, and hyperalgesia in rats. Read More

Int J Environ Res Public Health 2020 May 28;17(11). Epub 2020 May 28.

Department of Radiology and Physical Medicine, University of Granada, E-18016 Granada, Spain.

Aim: To analyze the levels of chronic fatigue in Spanish women with endometriosis and its relationship with their psychosocial status and quality of life (QoL).

Methods: A total of 230 Spanish women with a clinical diagnosis of endometriosis were recruited. Chronic fatigue (Piper Fatigue Scale) and pelvic pain (Numeric Rating Scale) were evaluated. Read More

Colorectal Dis 2020 May 29. Epub 2020 May 29.

Department of General Surgery, Ramón y Cajal University Hospital, Madrid, Spain.

Endometriosis is a frequent cause of chronic pelvic pain in women of childbearing age, resulting in a significant deterioration in their quality of life. Inflammation can affect the reproductive organs, rectum and bladder. Medical treatment is considered the first line of management, although it can prove insufficient in many cases. Read More

J Gynecol Obstet Hum Reprod 2020 May 24:101769. Epub 2020 May 24.

Department of Gynecology-Obstetrics and Reproductive Medecine, 38 Boulevard Jean Monnet, 44000, Nantes, France; Pelvic Pain Center, Nantes, France. Electronic address:

Introduction: To classify persistent perineal and pelvic postpartum pain using the classification usually employed in chronic pelvic pain.

Material And Method: Prospective observational study including all women who have consulted an algologist or gynecologist at one of the six French centers for a chronic pain (superior or equal to 3 months) spontaneous linked by the mother with her childbirth were included. During semi-directed interviews, a questionnaire regarding sociodemographic factors and detailed questions about pain were collected. Read More

Int J Environ Res Public Health 2020 May 21;17(10). Epub 2020 May 21.

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.

The objective was to evaluate the quality of life and the incidence of depression among women suffering from endometriosis. Afterwards, the dependency between pelvic pain, its severity and stages of endometriosis were analyzed. The study protocol included women of reproductive ages with confirmed endometriosis. Read More

J Minim Invasive Gynecol 2020 May 23. Epub 2020 May 23.

Endoscopica Malzoni, Center for Advanced Endoscopic Gynecologic Surgery, Avellino, Italy. Electronic address:

Objective: To show the surgical steps used to perform rectal disc excision in a context of deep infiltrating endometriosis characterized by contiguity between intestinal lesion and retrocervical region.

Design: Step-by-step video demonstration of the technique.

Setting: Although surgical options for the management of rectosigmoid endometriosis have increasingly been investigated, there is no consensus regarding patient eligibility for shaving, discoid or segmental resection. Read More

Am J Clin Nutr 2020 May 26. Epub 2020 May 26.

Boston Center for Endometriosis, Boston Children's Hospital and Brigham and Women's Hospital, Boston, MA, USA.

Background: Adolescents with endometriosis are a particularly underserved population who struggle with chronic pain. Despite widespread use, there are no published trials examining the individual effects of vitamin D and omega-3 (n-3) fatty acid supplementation on endometriosis-associated pain in adolescents.

Objectives: We aimed to determine whether supplementation with vitamin D or ω-3 fatty acids remediates pain, changes frequency of pain medication usage, or affects quality of life in young women with endometriosis. Read More

Virus Genes 2020 May 23. Epub 2020 May 23.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.

The question of whether some cases of interstitial cystitis may have an infectious etiology has been debated for some time. Previous studies have looked for the presence of certain specific viruses, but generally did not use the types of sensitive and unbiased approaches that are currently available. As part of the MAPP (Multidisciplinary Approach to the Study of Chronic Pelvic Pain) Research Network, we examined urine specimens from interstitial cystitis patients who provided specimens over time and also reported various symptoms at the time of urine collection. Read More

Arch Gynecol Obstet 2020 Jul 23;302(1):165-172. Epub 2020 May 23.

Endometriosis Center, Acibadem Fulya Hospital, Istanbul, Turkey.

Purpose: This is a retrospective cohort study that evaluates the postoperative pain findings of a consecutive series of laparoscopic surgeries for deep endometriosis (DE).

Methods: This multi-center retrospective cohort study was carried out in university hospitals (Istanbul, Turkey). Sixty-five patients diagnosed through bimanual gynecologic examination, gynecologic ultrasound or magnetic resonance imaging-confirmed endometrioma and DE together; who underwent a laparoscopic surgery between 2013 and 2019 by a team of gynecologists, colorectal surgeons, and a urologist were retrospectively evaluated. Read More

Rehabilitacion (Madr) 2020 May 6. Epub 2020 May 6.

Servicio de Rehabilitación, Hospital Universitario Santa Cristina, Madrid, España.

Objective: To determine whether a multimodal rehabilitation protocol (Biofeedback [BFB] plus capacitive-resistive [INDIBA®] radiofrequency [RF]) reduces pain and increases muscular strength in patients with chronic pelvic pain (CPP) and dyspareunia.

Material And Methods: We performed a prospective, quasi-experimental, before-after study in 37 patients with CPP and/or dyspareunia referred to the Rehabilitation Department of Hospital Universitario Santa Cristina (January 2016 to December 2018). The protocol consisted of 8 sessions of pelvic floor exercises assisted by manometric BFB (15min of tonic/phasic exercises each) supervised by a physiotherapist, followed by suprapubic and perineovaginal bipolar RF [capacitive(5 min)/resistive(10 min)]. Read More

BJU Int 2020 May 21. Epub 2020 May 21.

Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI-CONICET), Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

Objectives: To assess the presence of self-reactive immune responses to seminal and prostate antigens (PAg), biomarkers of inflammation of the male genital tract and semen quality parameters in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).

Subjects And Methods: peripheral blood and semen samples were collected from CP/CPPS patients and age-matched healthy control volunteers. The analysis of lymphoproliferative responses of peripheral blood mononuclear cells (PBMC) to different seminal plasma-derived and purified PAg, serum autoantibodies specific to PAg, leukocyte subpopulations and inflammatory cytokines in semen, sperm apoptosis/necrosis, and semen quality parameters were performed. Read More

Res Nurs Health 2020 May 20. Epub 2020 May 20.

School of Nursing and Midwifery, Robert Gordon University, Aberdeen, Scotland.

J Sex Res 2020 May 20:1-13. Epub 2020 May 20.

Department of Psychology, Université de Montréal.

Although facilitative and negative partner responses are known to impact couples' adaptation to provoked vestibulodynia (PVD), a chronic genito-pelvic pain condition, it is still unknown what leads individuals to adopt or perceive such adaptative or detrimental behaviors. Attachment influences sexual and relationship adjustment, emotional reactivity and perceived support in romantic relationships, and as such could be associated with partner responses. This study aimed at examining the mediating role of facilitative and negative partner responses in the associations between attachment and relationship and sexual adjustment in 125 couples coping with PVD. Read More

Transl Androl Urol 2020 Apr;9(2):485-493

Department of Andrology, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai 519015, China.

Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a chronic disease with a variety of psychosocial and somatic symptoms. CP/CPPS has substantial health care costs with unclear etiology, which may be caused by psychosocial factors. Moreover, previous studies suggested that cognitive processes played a crucial role in the perception of somatic pain. Read More

Transl Androl Urol 2020 Apr;9(2):398-404

Department of Urology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Background: Although empirical antibacterial treatments are currently recommended for inflammatory chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), physicians cannot verify infections in most cases. Therefore, in this study, the microbiota of semen was investigated via pyrosequencing to obtain evidence underlying infectious disease.

Methods: Patients diagnosed with CP/CPPS (n=17) and healthy volunteers (n=4) participated in the study. Read More

Transl Androl Urol 2020 Apr;9(2):391-397

Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background: Chronic prostatitis/chronic pelvic pain syndrome type III (CP/CPPS) is associated with pelvic pain, sexual dysfunction and irritative voiding. Sustained symptom relief has proven difficult with alpha blockers, antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Phosphodiesterase type 5 (PDE5) inhibitors (PDE5is) have the potential to alleviate bladder urgency, relax the pelvic floor, and correct underlying erectile dysfunction; however, few studies have investigated the application of PDE5i's to CP/CPPS. Read More

J Gynecol Obstet Hum Reprod 2020 May 12:101796. Epub 2020 May 12.

Department of Obstetrics and Gynecology, Univesity of Debrecen, Faculty of Medicine, 98. Nagyerdei krt., Debrecen 4012, Hungary. Electronic address:

Introduction: Endometriosis is a chronic systemic disease, which influence negatively the quality of life of affected women and responsible for infertility and chronic pelvic pain. Pathophysiology of the disease is still enigmatic, but insufficient immune surveillance may play a role in it. Peripheral natural immune cell function is rarely examined. Read More

Surg Endosc 2020 May 14. Epub 2020 May 14.

Department of Surgery, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.

Background: Adhesions are a major cause of long-term postsurgical complications in abdominal and pelvic surgery. Existing adhesion scores primarily measure morphological characteristics of adhesions that do not necessarily correlate with morbidity. The aim of this study was to develop a clinical adhesion score (CLAS) measuring overall clinical morbidity of adhesion-related complications in abdominal and pelvic surgery. Read More

Spine Surg Relat Res 2020 1;4(2):135-141. Epub 2019 Nov 1.

Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.

Introduction: Although intervertebral disc degeneration (IVDD) and spinopelvic malalignment are likely key structural features of spinal degeneration and chronic low back pain (CLBP), the correlation analysis has not been fully conducted. This cross-sectional quantitative magnetic resonance imaging (MRI) T2 mapping study aimed to elucidate the association between IVDD and spinopelvic alignment in CLBP patients.

Methods: The subjects included 45 CLBP patients (19 men and 26 women; mean age, 63. Read More

Minerva Ginecol 2020 Apr;72(2):106-118

Cleveland Clinic, London, UK.

Endometriosis is a disease of reproductive age women that is commonly characterized by symptoms that often negatively impact quality of life. The clinical management of endometriosis remains highly variable and mostly influenced by geographic location, practice patterns, and breadth of clinician experience. This variability in treatment has inspired a trend towards multidisciplinary and specialized care of patients suffering from this disease. Read More

Gynecol Endocrinol 2020 May 13:1-5. Epub 2020 May 13.

Department of Medical Sciences and Public Health, University of Cagliari, Monserrato, CA, Italy.

Endometriosis is a chronic inflammatory disease of women of reproductive age. Small bowel (SB) permeability and lipopolysaccharides (LPS) could play a role in the perduration of low grade inflammation status and the pathogenesis of endometriosis. To clarify this hypothesis, we measured SB permeability through plasma values of LPS and urinary secretion of lactulose (La), mannitol (Ma) and their ratio (L/M) in patients with endometriosis compared with healthy controls (HC). Read More

Cent European J Urol 2020 23;73(1):46-48. Epub 2020 Mar 23.

Centre Hospitalier Wallonie Picarde, Tournai, Belgium.

Pudendal nerve (PN) entrapment is one of the most misunderstood and underdiagnosed medical conditions. It is recognized as a cause of chronic pelvic pain syndrome. However, due to the pudendal nerve's mixed composition and complex anatomy, the presenting symptoms are varied and go beyond pain, depending on the entrapment's nature, location and duration. Read More

Hip Int 2020 May 11:1120700020922202. Epub 2020 May 11.

Imperial College Healthcare NHS Trust, London, UK.

Introduction: Periacetabular osteotomy (PAO) is an established treatment for symptomatic acetabular dysplasia in skeletally mature individuals without arthritis. Pelvic nonunion and associated stress fractures are under-reported. Nonunited stress fractures can cause continued buttock pain and pelvic instability. Read More

Am J Obstet Gynecol 2020 May 6. Epub 2020 May 6.

Cincinnati, Ohio, TriHealth Good Samaritan Hospital, Division FPMRS.

Background: Improving the patient experience, controlling pain with non-opiate therapies, and preparing for value based reimbursement are increasingly important foci for both physicians and hospitals.

Objectives: We sought to determine if the addition of music and a natural landscape image to postoperative hospital rooms would result in improved pain and satisfaction scores among inpatients undergoing pelvic reconstructive surgery.

Study Design: This was an Institutional Review Board approved, randomized controlled trial. Read More

Acta Obstet Gynecol Scand 2020 May 9. Epub 2020 May 9.

Department of Obstetrics and Gynecology, University Hospital of North Norway, Tromsø, Norway.

Introduction: Chronic pelvic pain in women is a complex condition, and physical therapy is recommended as part of a broader treatment approach. The objective of this study was to compare structured group-based multimodal physical therapy in a hospital setting (intervention group) with primary-care physical therapy (comparator group) for women with chronic pelvic pain.

Material And Methods: Women aged 20-65 years with pelvic pain ≥6 months and referred for physical therapy were eligible. Read More

Scand J Pain 2020 May 8. Epub 2020 May 8.

Department of Obstetrics and Gynaecology in Linköping, and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Background and aims Psychological traits such as pain catastrophizing may play a role in the development of chronic pelvic pain (CPP). Pain catastrophizing is the tendency to amplify negative cognitive and emotional pain processes. The Pain Catastrophizing Scale (PCS) assesses elements of pain catastrophizing divided into three subgroups of factors (rumination, helplessness and magnification). Read More

J Palliat Med 2020 May 5. Epub 2020 May 5.

Research Unit, Dr. Negrín University Hospital, Las Palmas de Gran Canaria, Spain.

Chronic pain secondary to treatment in cancer survivors without tumor evidence is not unusual. Its management often requires specific approaches that are different from those applied for cancer patients with advanced disease and short life expectancy. Some studies have described clinical benefit with ozone therapy (OT) in the management of pain and side effects secondary to cancer treatment. Read More

Curr Pain Headache Rep 2020 May 6;24(6):27. Epub 2020 May 6.

Department of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.

Purpose Of Review: Urologic chronic pelvic pain syndrome (UCPPS) is a chronic, noncyclic pain condition which can lead to significant patient morbidity and disability. It is defined by pain in the pelvic region, lasting for greater than 3 to 6 months, with no readily identifiable disease process. The aim of this review is to provide a comprehensive update of diagnosis and treatment of UCPPS. Read More

Rheumatol Int 2020 May 6. Epub 2020 May 6.

Department of Physiotherapy, Speech Therapy and Occupational Therapy, School of Medicine, Faculty of Medicine, University of São Paulo, Cipotanea Street, 51, São Paulo, SP, Brazil.

Background: Fibromyalgia (FM) is characterized by chronic and widespread pain, sleep disturbances, fatigue, psychological distress and morning stiffness. These patients also present symptoms such as depression, sexual dysfunctions and reproductive problems. Sexuality involves several aspects, including pelvic floor functionality, and one question is whether the sexual performance of women with fibromyalgia is associated with pelvic floor function or other characteristics of the disease. Read More

Int J Environ Res Public Health 2020 Apr 26;17(9). Epub 2020 Apr 26.

Department of Health Systems Management, Ariel University, 40700 Ariel, Israel.

Background: Chronic pelvic pain syndrome (CPPS) is one of the common diseases in urology and gynecology. CPPS is a multifactorial disorder where pain may originate in any of the urogynecological, gastrointestinal, pelvic musculoskeletal, or nervous systems. The symptoms of CPPS appear to result from an interplay between psychological factors and dysfunction in the immune, neurological, and endocrine systems. Read More

Nat Rev Dis Primers 2020 04 30;6(1):36. Epub 2020 Apr 30.

Department of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.

Vulvodynia is a condition that occurs in 8-10% of women of all ages and is characterized by pain at the vulva that is present during sexual and/or non-sexual situations. Diagnosis is established through careful medical history and pelvic examination, including the cotton-swab test. The onset and maintenance of vulvodynia involves a complex interplay of peripheral and central pain mechanisms, pelvic floor muscle and autonomic dysfunction, anxiety, depression and childhood maltreatment as well as cognitive-affective, behavioural and interpersonal factors. Read More

Contraception 2020 Apr 27. Epub 2020 Apr 27.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, United States; Department of Obstetrics & Gynecology, Washington University School of Medicine, St. Louis, MO, United States. Electronic address:

Background: Pelvic pain has been associated with Essure, a permanent contraceptive implant. Here we describe histopathologic findings in long-term Essure users with chronic pelvic pain.

Methods: We descriptively evaluated and compared histopathologic features of hysterectomy specimens removed for a primary diagnosis of chronic pelvic pain from women with (n = 3) and without (n = 3) prior placement of Essure coils (mean of 8. Read More

Lancet Glob Health 2020 May;8(5):e711-e720

Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada. Electronic address:

Background: The Lancet Commission on Global Surgery established the Three Delays framework, categorising delays in accessing timely surgical care into delays in seeking care (First Delay), reaching care (Second Delay), and receiving care (Third Delay). Globally, knowledge gaps regarding delays for fracture care, and the lack of large prospective studies informed the rationale for our international observational study. We investigated delays in hospital admission as a surrogate for accessing timely fracture care and explored factors associated with delayed hospital admission. Read More

Cureus 2020 Mar 27;12(3):e7437. Epub 2020 Mar 27.

Orthopaedics, Panagiotis & Aglaia Kyriakou Children's Hospital, Athens, GRC.

Purpose The treatment of painful and chronic dislocated hip in children with severe cerebral palsy (CP) is particularly demanding and controversial. Numerous surgical techniques have been described, and their outcomes vary a lot. The purpose of the present study is to evaluate a new method, which combines varus derotational subtrochanteric osteotomy (VDSO) and external osteosynthesis: (VDSOEO). Read More

Urologiia 2020 Apr(2):16-22

Department of Urology and Human Reproductive Health, Rostov State Medical University, Rostov-on-Don, Russia.

Background: Chronic bacterial prostatitis (CBP) and chronic prostatitis/chronic pelvic pain syndrome IIIa (CP/CPPS IIIa) are separate nosologies defined diagnostic verification criteria according to the NIH-NIDDK classification (1995). The identification of enterobacteria in the prostatic secretion (PS) has long been a criterion for the diagnosis of CBP, while PS in patients suffering CP/CPPS IIIa was considered as "sterile". However, the introduction of various methods of PS`s in-depth analysis and UPOINTS classification (2010) development with the allocation of site I (infection) allows us to consider the infectious factor as an etiological predictor of the initiation of inflammation in the prostate with CP/CPPS IIIa. Read More

Sci Rep 2020 Apr 23;10(1):6901. Epub 2020 Apr 23.

Miller Scientific, Johnson City, TN, United States.

The objective of this review was to compare the efficacy and safety of conservative surgery with or without adjunctive presacral neurectomy (PN) for chronic endometriosis-related pelvic pain. In a systematic review with meta-analysis, randomized or nonrandomized controlled studies of conservative endometriosis surgery with or without adjunctive PN were included. Main outcomes were treatment failure (the proportion of women in which surgery failed to adequately resolve midline pain) and the frequency of operative and postoperative complications. Read More

Arch Phys Med Rehabil 2020 Apr 20. Epub 2020 Apr 20.

Department of Physical Therapy, Faculty of Health Sciences, University of Granada, Granada, Spain. Electronic address:

Objective: To assess the effectiveness of an individualized comprehensive rehabilitation program (ICPR) on impaired postural control, pain, self-perceived health status, and functionality in women with chronic pelvic pain.

Design: Randomized controlled trial.

Setting: Women with chronic pelvic pain were recruited from the Gynecology Department of the University Hospital San Cecilio in Granada, Spain. Read More

Curr Opin Obstet Gynecol 2020 Apr 18. Epub 2020 Apr 18.

Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Purpose Of Review: Enhanced recovery after surgery (ERAS) programs aim to expedite functional recovery and improve surgical outcomes without increasing complications or cost. First championed by colorectal surgeons, ERAS protocols are now widely utilized among surgical subspecialties. The present review focuses on use of ERAS pathways in minimally invasive gynecologic surgery (MIGS) and risk factors for suboptimal outcomes in this population. Read More

Neuromodulation 2020 Apr 22. Epub 2020 Apr 22.

Department of Obstetrics and Gynecology, Justus-Liebig-University Giessen, Giessen, Germany.

Objective: The aim of this study was to report on the use of laparoscopic implantation of leads on the branches of the sacral plexus for neuromodulation in the treatment of chronic pelvic pain (CPP) in a multidisciplinary setting with the help of electrophysiological neuromonitoring.

Materials And Methods: Between 2012 and 2019, six female patients complaining of chronic pain and bladder and bowel dysfunctions underwent laparoscopic exposure and nerve identification with the help of electrophysiological neuromonitoring. A lead was placed laparoscopically in direct contact with the affected nerve. Read More

J Family Med Prim Care 2020 Feb 28;9(2):978-984. Epub 2020 Feb 28.

Department of Health Psychology, University of Leuven, Leuven, Belgium.

Background: Malalignment in the pelvic and spinal column disturbs the balance and decreases the postural control ability. Malalignment is known as one of the main causes of back pain particularly the nonspecific chronic low back pain (NSCLBP). The aim of the study is to compare the effect of muscle energy technique (MET), craniosacral therapy (CST), and sensorimotor training (SMT) on postural control in patients with NSCLBP. Read More

BMC Womens Health 2020 Apr 21;20(1):75. Epub 2020 Apr 21.

Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 9 Jinsui Road, Zhujiang Newtown, Tianhe District, Guangzhou, 510623, China.

Background: Diverticulum, one of the long-term sequelae of cesarean section, can cause abnormal uterine bleeding, dysmenorrhea and chronic pelvic pain. Hysteroscopic resection of diverticula is thought to reduce abnormal uterine bleeding and chronic pelvic pain. In this study, we aim to describe the improvement after hysteroscopic resection of cesarean section diverticula (CSD) in women without childbearing intention, and to explore the variables associated with poor prognosis. Read More

Spine Deform 2020 Apr 18. Epub 2020 Apr 18.

Department of Orthopedic Surgery, Boston Children's Hospital, Hunnewell 2, 300 Longwood Avenue, Boston, MA, 02115, USA.

Study Design: Retrospective case series.

Objectives: To describe how pediatric patients with spinal and pelvic osteomyelitis are diagnosed and treated and assess the diagnostic value of magnetic resonance imaging (MRI), needle aspiration biopsy (NAB), and blood cultures in this population. Spinal and pelvic osteomyelitis de novo are uncommon in children and minimal literature exists on the subject. Read More

Ann Clin Microbiol Antimicrob 2020 Apr 16;19(1):15. Epub 2020 Apr 16.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.

Endometriosis (EMS) is a multifactorial disease that affects 10%-15% women of reproductive age and is associated with chronic pelvic pain and infertility. The pathogenesis of EMS has not been consistently explained until now. In this study, we involved 36 endometriosis patients and 14 control subjects who performed laparoscopic surgery due to gynecological benign tumor. Read More

J Urol 2020 Apr 14:101097JU0000000000001080. Epub 2020 Apr 14.

Department of Biostatistics, Epidemiology & Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Purpose: To evaluate and identify baseline factors associated with change in health-related quality of life (HRQOL) among patients with interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).

Methods: A total of 191 men and 233 women with IC/BPS or CP/CPPS (collectively referred to as urologic chronic pelvic pain syndrome, or UCPPS) were followed for 12 months with bimonthly completion of the Short Form 12 (SF-12) to assess general mental and physical HRQOL, and with biweekly assessment of condition-specific HRQOL using the Genitourinary Pain Index. A functional clustering algorithm was used to classify participants as improved, stable, or worsened for each HRQOL measure. Read More

J Urol 2020 Apr 15:101097JU0000000000001045. Epub 2020 Apr 15.

Int J Urol 2020 Apr 14. Epub 2020 Apr 14.

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

The clinical guidelines for interstitial cystitis and related symptomatic conditions were revised by updating our previous guidelines. The current guidelines define interstitial cystitis/bladder pain syndrome as a condition with chronic pelvic pain, pressure or discomfort perceived to be related to the urinary bladder accompanied by other urinary symptoms, such as persistent urge to void or urinary frequency in the absence of confusable diseases. The characteristic symptom complex is collectively referred as hypersensitive bladder symptoms. Read More

Reprod Biol Endocrinol 2020 Apr 14;18(1):28. Epub 2020 Apr 14.

Academic Unit of Reproductive and Developmental Medicine, The University of Sheffield, The Jessop Wing, Tree Root Walk, Sheffield, S10 3HY, Sheffield, UK.

Background: Chronic cyclic pelvic pain (CCPP) affects women's quality of life and pituitary downregulation is often used for symptomatic relief. However, prolonged suppression of ovarian function is associated with menopausal side effects and can lead to osteoporosis. Currently, the use of gonadotropin releasing hormone agonists (GnRHa) for treatment of CCPP is usually restricted to 6-9 months, limiting their efficacy. Read More

Ergonomics 2020 Jun 22;63(6):724-734. Epub 2020 Apr 22.

College of Engineering, University of Kentucky, Lexington, KY, USA.

This study examined associations and changes overtime in low back kinematics and disability, pain, pain catastrophizing, and depression and assessed whether associations and changes overtime varied between individuals who meet the classification criteria for chronic low back pain at 6 months and those who do not. Findings suggested that those persons with a higher ratio of lumbar contribution to thorax motion and smaller pelvic tilt during forward bending had higher scores on measures of disability, pain and pain catastrophizing. This same association was found in those who met classification criteria for chronic low back pain at 6 months. Read More