474 results match your criteria Chronic Paroxysmal Hemicrania


Paroxysmal hemicrania or short-lasting unilateral neuralgiform headache attacks with trigeminal neuralgia - functional neuroimaging findings.

Neurol Neurochir Pol 2022 Mar 21. Epub 2022 Mar 21.

Warsaw University of Technology, Faculty of Electronics and Information Technology, The Institute of Radioelectronics and Multimedia Technology, Warsaw, Poland.

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The spectrum of indomethacin-responsive headaches in children and adolescents.

Cephalalgia 2022 Jul 18;42(8):793-797. Epub 2022 Mar 18.

Division of Neurology, Department of Pediatrics, Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: Headaches with marked, specific response to indomethacin occur in children, but the phenotypic spectrum of this phenomenon has not been well-studied.

Methods: We reviewed pediatric patients with headache showing ≥80% improvement with indomethacin, from seven academic medical centers.

Results: We included 32 pediatric patients (16 females). Read More

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[Autonomic Disorders in Trigeminal Autonomic Cephalalgias: An Update].

Authors:
Hisanori Kowa

Brain Nerve 2022 Mar;74(3):263-270

Department of Neurology, National Hospital Organization Matsue Medical Center.

The term trigeminal autonomic cephalalgias (TACs) was introduced in the 2 edition of the International Classification of Headache Disorders, and has been retained in the 3 edition. TACs include cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks, hemicrania continua, and probable trigeminal autonomic cephalalgia. Headaches classified as TACs share clinical features with unilateral headache and usually present with prominent lateralized and ipsilateral cranial parasympathetic autonomic features, including the following: (1) conjunctival injection and/or lacrimation, (2) nasal congestion and/or rhinorrhea, (3) eyelid edema, (4) forehead and facial sweating, (5) miosis and/or ptosis. Read More

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[Trigeminal autonomic cephalgias: features of diagnosis and treatment].

Zh Nevrol Psikhiatr Im S S Korsakova 2021 ;121(10):105-112

South Ural State Medical University, Chelyabinsk, Russia.

Trigeminal autonomic cephalgias is a group of primary headaches, including cluster headache, paroxysmal hemicrania and hemicrania continua, as well as two forms of short- lasting unilateral neuralgiform headache attacks, the complexity of diagnosis of which is determined by the low prevalence and some similarity of clinical manifestations both among themselves and with other diseases in particular with migraine and trigeminal neuralgia. Despite the rather short duration of headache attacks, the intensity of the pain syndrome reaches a severe and very severe degree, and the high frequency of paroxysms per day significantly complicates abortion treatment and leads to a pronounced professional and social maladjustment. At the same time, the possibility of using effective specific prophylactic therapy determines the importance of accurate diagnosis and, therefore, the knowledge of neurologists on this issue. Read More

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December 2021

A New Treatment Option for Children With Refractory Chronic Paroxysmal Hemicranias: Occipital Nerve Stimulation.

Pediatr Neurol 2021 12 24;125:18-19. Epub 2021 Sep 24.

Neurosurgery Department, Pitié Salpêtrière Sorbonne University Hospital, Paris, France.

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December 2021

Aura in trigeminal autonomic cephalalgia is probably mediated by comorbid migraine with aura.

Cephalalgia 2022 01 18;42(1):31-36. Epub 2021 Aug 18.

Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Objective: The presence of aura is rare in cluster headache, and even rarer in other trigeminal autonomic cephalalgias. We hypothesized that the presence of aura in patients with trigeminal autonomic cephalalgias is frequently an epiphenomenon and mediated by comorbid migraine with aura.

Methods: The study retrospectively reviewed 480 patients with trigeminal autonomic cephalalgia in a tertiary medical center for 10 years. Read More

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January 2022

Pediatric-onset trigeminal autonomic cephalalgias: A systematic review and meta-analysis.

Cephalalgia 2021 11 18;41(13):1382-1395. Epub 2021 Aug 18.

Department of Neurosurgery, 12340University of Texas Health Science Center at Houston, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Background And Objective: There are five headache disorders composing the trigeminal autonomic cephalalgias (cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT), short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA), and hemicrania continua). Little is known about these disorders in the pediatric population. The objectives of this study are to report the full age ranges of pediatric trigeminal autonomic cephalalgias and to determine if pediatric-onset trigeminal autonomic cephalalgias display similar signs and symptoms as adult onset. Read More

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November 2021

Indomethacin has no effect on trigeminally provoked parasympathetic output.

Cephalalgia 2022 01 18;42(1):37-43. Epub 2021 Aug 18.

Department of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany.

Background: Unlike other non-steroidal anti-inflammatory drugs, indomethacin has been shown to be highly effective in two forms of trigeminal autonomic cephalalgias, hemicrania continua and paroxysmal hemicrania and in some forms of idiopathic stabbing headaches. This specificity is unique in the headache field. Previous findings suggest the involvement of the trigeminal autonomic reflex to play an important role in the pathophysiology of these diseases. Read More

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January 2022

A Combination of Indomethacin Farnesyl and Amitriptyline Is Effective for Continuous Interictal Pain with Probable Chronic Paroxysmal Hemicrania.

Intern Med 2022 Feb 26;61(3):413-417. Epub 2021 Jun 26.

Department of Neurology, Headache Center, Tominaga Hospital, Japan.

A 26-year-old woman with a history of migraine reported right-sided, severe stabbing orbital pain with cranial autonomic symptoms (CASs) for approximately 2 years. The attack duration was approximately 30 minutes, with a frequency of twice per day. Taking loxoprofen was ineffective. Read More

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February 2022

The Promising Effect of Nerve Decompression in Trigeminal Autonomic Cephalalgias: Report of Case Series.

Front Neurol 2021 7;12:678749. Epub 2021 Jun 7.

Department of Neuroscience, University of California, San Diego, San Diego, CA, United States.

Trigeminal Autonomic Cephalalgias (TAC) are excruciating headaches with limited treatment options. The chronic forms of TACs, including chronic cluster, chronic paroxysmal hemicrania, and hemicrania continua, are disabling conditions. In addition to drug therapy, there are some studies regarding nerve blocking and nerve stimulation with acceptable results. Read More

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Indomethacin-responsive headaches-A narrative review.

Headache 2021 May;61(5):700-714

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Background: Indomethacin is a nonsteroidal anti-inflammatory drug whose mechanism of action in certain types of headache disorders remains unknown. The so-called indomethacin-responsive headache disorders consist of a group of conditions with a very different presentation that have a particularly good response to indomethacin. The response is so distinct as to be used in the definition of two: hemicrania continua and paroxysmal hemicrania. Read More

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Noninvasive Neuromodulation in Headache: An Update.

Neurol India 2021 Mar-Apr;69(12 Suppl 1):S183-S193

The Headache Service, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Background: Migraine is a common disabling primary headache condition. Although strives have been made in treatment, there remains an unmet need for safe, effective acute, and preventative treatments. The promising concept of neuromodulation of relevant neuronal targets in a noninvasive fashion for the treatment of primary headache disorders has led to the trial of numerous devices over the years. Read More

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Paroxysmal Hemicrania: An Update.

Neurol India 2021 Mar-Apr;69(Supplement):S135-S143

Department of Neurology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Paroxysmal Hemicrania (PH) is classified under trigeminal autonomic cephalalgia (TAC) as per the International Classification of Headache Disorders (ICHD). Since the first description by 0ttar Sjaastad and Inge Dale in 1974, PH has been reported by many authors. A greater understanding of PH phenotype and pathophysiology has resulted in the evolution of its diagnostic criteria, and management. Read More

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Role of Functional Neuroimaging in Primary Headache Disorders.

Neurol India 2021 Mar-Apr;69(Supplement):S10-S16

Department of Neurology, Klinikum Weser-Egge, Höxter, Germany.

Background: Key structures for the pathophysiology of primary headache disorders such as migraine, cluster headache, and other trigeminal autonomic cephalalgias were identified by imaging in the past years.

Objective: Available data on functional imaging in primary headache disorders are summarized in this review.

Material And Methods: We performed a MEDLINE search on December 27, 2020 using the search terms "primary headache" AND "imaging" that returned 453 results in English, out of which 137 were labeled reviews. Read More

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Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding.

Eur J Neurol 2021 07 18;28(7):2443-2455. Epub 2021 May 18.

PharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.

Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing/autonomic symptoms (SUNCT/SUNA). Treating these rare, severe headache conditions often requires off-label drugs that have uncertain teratogenic potential. Read More

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Paroxysmal hemifacial pain: A report of two cases.

Headache 2021 Apr 13;61(4):683-686. Epub 2021 Apr 13.

Orofacial Pain Center, Naval Postgraduate Dental School, Bethesda, MD, USA.

Paroxysmal hemifacial pain (PHFP) is the orofacial counterpart to paroxysmal hemicrania headaches. This paper reports the cases of two patients suffering from episodic attacks of severe unilateral facial pain. In both cases, pain attacks were absolutely responsive to therapeutic doses of indomethacin. Read More

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Long-Term Outcome of Indomethacin Treatment in Pediatric Patients with Paroxysmal Hemicrania-A Case Series.

Children (Basel) 2021 Feb 3;8(2). Epub 2021 Feb 3.

German Paediatric Pain Centre, Children's and Adolescents' Hospital, Witten/Herdecke University, 45711 Datteln, Germany.

Paroxysmal Hemicrania is a rare form of primary headache in children and adolescents, belonging to the group of trigeminal autonomic cephalalgias. Patients suffer from severe, short-lasting unilateral headaches accompanied by symptoms of the autonomic system on the same side of the head. The short duration of attacks distinguishes Paroxysmal Hemicrania from other trigeminal autonomic cephalalgias. Read More

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February 2021

Carotid body tumor as a potential cause of paroxysmal hemicrania.

J Vasc Surg Cases Innov Tech 2020 Dec 21;6(4):495-497. Epub 2020 Aug 21.

Carle Heart and Vascular Institute, Urbana, Ill.

A 70-year-old woman presented to our emergency department with a severe left-sided headache. The headache's location and accompanying symptoms are consistent with paroxysmal hemicrania. On workup, a cervical computed tomography scan incidentally revealed a left carotid body tumor, and the patient was referred to vascular surgery. Read More

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December 2020

Paroxysmal hemicrania masquerading as a stroke in an elderly gentleman: case report.

BMC Geriatr 2020 10 7;20(1):392. Epub 2020 Oct 7.

Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

Background: Paroxysmal hemicrania has not been associated with ipsilateral weakness, loss of sensation and Horner's syndrome. This report is the first of its kind documented in literature.

Case Presentation: This was an elderly, sixty-five-year-old Chinese male who presented with a headache fulfilling criteria of paroxysmal hemicrania and was found to have signs of ipsilateral conjunctival injection, Horner's syndrome, weakness and loss of sensation; with resolution of the patient's physical signs after relief of the headache. Read More

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October 2020

SUNCT/SUNA in children and adolescents: Application of ICHD-3 criteria and treatment response: Case series of 13 SUNCT/SUNA pediatric cases.

Cephalalgia 2021 01 31;41(1):112-116. Epub 2020 Aug 31.

Department of Neurology, Cincinnati Children Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.

Introduction: Trigeminal autonomic cephalalgias (TACs) are characterized by paroxysmal attacks of unilateral primary headaches associated with ipsilateral craniofacial autonomic symptoms. In this pediatric case series, 13 cases of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)/short-lasting unilateral neuralgiform headache with autonomic symptoms (SUNA), including children ages 3-18 years, are discussed. This paper reviews the application of International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria especially in children presenting with SUNCT or SUNA. Read More

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January 2021

Cluster headache and TACs: state of the art.

Neurol Sci 2020 Dec;41(Suppl 2):367-375

Neuroalgology Unit, IRCCS Fondazione Istituto Neurologico "Carlo Besta", Milan, Italy.

Cluster headache (CH), paroxysmal hemicrania (PH), short-lasting unilateral neuralgiform headache attacks (including SUNCT and SUNA), and hemicrania continua (HC) compose the group of trigeminal autonomic cephalalgias (TACs). Here, we review the recent advances in the field and summarize the current knowledge about the origin of these headaches. Similar to the other primary headaches, the pathogenesis is still much obscure. Read More

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December 2020

Differential actions of indomethacin: clinical relevance in headache.

Pain 2021 02;162(2):591-599

Headache Group-Department of Neurology, University of California, San Francisco, San Francisco, CA, United States. Dr. Summ is now with the Department of Neurology and Research Center of Neurosensory Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany. Dr. Andreou is now with the Headache Research-Wolfson CARD, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom. Dr. Akerman is now with the Department of Neural and Pain Sciences, University of Maryland Baltimore, Baltimore, MD, United States.

Abstract: Nonsteroidal anti-inflammatory drugs, cyclooxygenase inhibitors, are used routinely in the treatment of primary headache disorders. Indomethacin is unique in its use in the diagnosis and treatment of hemicrania continua and paroxysmal hemicrania. The mechanism of this specific action is not fully understood, although an interaction with nitric oxide (NO) signaling pathways has been suggested. Read More

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February 2021

[Cluster headache and other trigeminal autonomic cephalalgias].

Ned Tijdschr Geneeskd 2020 07 2;164. Epub 2020 Jul 2.

LUMC, afd. Neurologie, Leiden.

Trigeminal autonomic cephalalgias (TACs) are a group of 4 different primary headache syndromes that have a lot of pathophysiological and clinical features in common. The 4 different TACs are: cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks and hemicrania continua. TACs are characterized by frequent, strictly unilateral, (very) intense headache attacks with ipsilateral cranial autonomic symptoms or intrinsic restlessness or both. Read More

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Very young age of onset in trigemino-autonomic cephalalgias - case report and review of the literature.

Cephalalgia 2020 10 14;40(12):1385-1388. Epub 2020 Jul 14.

Faculty of Medicine, University of Münster, Münster, Germany.

Background: Trigemino-autonomic cephalalgias are very rare disorders and even rarer in children and adolescents. We report the onset of paroxysmal hemicrania in a very young girl and reviewed the scientific literature for similar cases.

Findings: We describe the case of a 1. Read More

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October 2020

Headache Attack Similar to Paroxismal Hemicrania Seen During Flight.

Aerosp Med Hum Perform 2020 Apr;91(4):373-375

Airplane headache (AH) is unique to plane travel and looks like a short duration migraine attack or paroxysmal hemicrania (PH) attack without any autonomic symptoms. Until now, there has been no documented association between AH and PH. We report a 50-yr-old healthy woman with a very severe and sudden pulsating headache located in the left frontal region with radiation into the left eye during takeoff which diminished within 10-15 min during her airplane journeys. Read More

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Headache in the Older Population: Causes, Diagnoses, and Treatments.

Curr Pain Headache Rep 2020 May 29;24(7):34. Epub 2020 May 29.

Department of Neurology, Mayo Clinic, Scottsdale, AZ, USA.

Purpose Of Review: Primary headaches are less common and differ in presentation in older versus younger individuals. Secondary headaches become more common among older patients.

Recent Findings: Diagnosis and management of headaches in those > 65 years are discussed. Read More

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Cerebral Sinus Venous Thrombosis Mimicking Probable Paroxysmal Hemicrania: A Case Report.

Headache 2020 05 2;60(5):992-993. Epub 2020 Mar 2.

Department of Neurology, Mayo Clinic, Rochester, MN, USA.

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Trigeminal Autonomic Cephalalgias.

Neurol Clin 2019 11 24;37(4):847-869. Epub 2019 Aug 24.

Department of Neurology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

The trigeminal autonomic cephalalgias (TACs) are a group of primary headache syndromes all marked by unilateral headache and ipsilateral cranial autonomic features. The TACs include cluster headache, paroxysmal hemicrania, short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing, and hemicrania continua. Pathophysiology includes the trigeminal pain system, autonomic system, hypothalamus, and more recently an identified role for the vagus nerve. Read More

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November 2019