14,213 results match your criteria Chronic Pain Syndrome


Management of patients presenting with generalized musculoskeletal pain and a suspicion of Lyme disease.

Med Mal Infect 2019 Feb 11. Epub 2019 Feb 11.

FHU INOVPAIN, centre d'évaluation et de traitement de la douleur, CHU de Timone, pôle de neurosciences cliniques, 13005 Marseille, France.

Lyme disease is caused by bacteria of the B. burgdorferi sensu lato complex, and can give polymorphic clinical manifestations that can affect several organs such as the skin, the central nervous system, or the joints. In recent years, patients' associations and physicians have been supporting the hypothesis that this infection would manifest as chronic generalized musculoskeletal pain symptoms, named "chronic Lyme disease". Read More

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http://dx.doi.org/10.1016/j.medmal.2019.01.008DOI Listing
February 2019

TRUSS inhibition protects against high fat diet (HFD)-stimulated brain injury by alleviation of inflammatory response.

Biochem Biophys Res Commun 2019 Feb 11. Epub 2019 Feb 11.

Department of Anesthesiology, The Affiliated Huxi Hospital of Jining Medical College, Shanxian Central Hospital, Shanxian, Shandong, 274300, China. Electronic address:

High fat diet (HFD)-induced obesity is associated with insulin resistance (IR) and other chronic, diet associated illnesses, including neuroinflammation and brain injury. However, the involvement of inflammatory response in HFD-elicited central nerve injury has yet to be fully determined. Recent studies have indicated that tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein (TRUSS), also known as TRPC4AP, plays an essential role in regulating inflammation via the meditation of NF-κB signaling. Read More

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http://dx.doi.org/10.1016/j.bbrc.2019.01.058DOI Listing
February 2019

Bisphosphonate-induced orbital inflammation in a patient on chronic immunosuppressive therapy.

BMC Ophthalmol 2019 Feb 14;19(1):51. Epub 2019 Feb 14.

Department of Ophthalmology, University of Kansas School of Medicine, 7400 State Line Rd, Prairie Village, Kansas, USA.

Background: To report a case of orbital inflammation after bisphosphonate infusion in a patient who was already receiving immunosuppressive therapy.

Case Presentation: A 56-year-old woman presented to the ophthalmology clinic with acute onset of right eye pain 24 h after receiving her first Zolendronic acid infusion. She has a past medical history of chronic inflammatory demyelinating polyneuropathy, Sjogren's syndrome, and systemic lupus erythematosus that have been controlled with immunosuppressive therapy for three years. Read More

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http://dx.doi.org/10.1186/s12886-019-1063-8DOI Listing
February 2019

[Indicators of the quality of life of patients with chronic biliary pancreatitis after various options for surgical treatment].

Voen Med Zh 2017 Apr;338(4):21-27

life indicators of patients (n=365) with chronic biliary pancreatitis before the operation, 6 months and up to 10 years after surgical intervention were studied. It was found that the decrease in the quality of life of patients before surgey is mainly due to pain syndrome. After 6 months after the operation, the work capacity and physica activity are gradually restored against the background of a reduction in the pain syndrome. Read More

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[Psychosomatic urology: how to treat chronic urological diseases].

Aktuelle Urol 2019 Feb 14. Epub 2019 Feb 14.

Ambulantes Rehabilitations-Zentrum für Urologie und Gynäkologie Heidelberg, Facharztpraxis für Urologie, Heidelberg.

In specialist urology clinics, 50 - 70 % of patients have chronic urological diseases such as recurrent urinary tract infections, a somatoform overactive bladder, adult and infantile enuresis, a chronic pelvic pain syndrome, and the psychosomatic form of post-prostatectomy incontinence. The 12-month prevalence of psychological disorders in the general adult population is 28 % 1. As many as 20 % of children and adolescents are found to have psychological abnormalities 2. Read More

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http://dx.doi.org/10.1055/a-0834-5989DOI Listing
February 2019

Manipulative Therapies: What Works.

Am Fam Physician 2019 Feb;99(4):248-252

University of Florida, Gainesville, FL, USA.

Manipulative therapies include osteopathic manipulative treatment and many other forms of manual therapies used to manage a variety of conditions in adults and children. Spinal manipulative therapy may provide short-term improvement in patients with acute or chronic low back pain, comparable with other standard treatments. When compared with oral analgesics, cervical manipulation and/or mobilization appears to provide better short-term pain relief and improved function in patients with neck pain. Read More

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February 2019

Evaluation of the efficacy of epiduroscopic adhesiolysis in failed back surgery syndrome

Turk J Med Sci 2019 Feb 11;49(1):249-257. Epub 2019 Feb 11.

Background/aim: We aimed to compare the results of the treatment of the patients with failed back surgery syndrome (FBSS) by mechanical lysis and steroid hylase injection via epiduroscopy due to their stabilization status and to detect the effect of pathological diagnostic markers on prognosis and ongoing treatment protocol.

Materials And Methods: Eighty-two patients with FBSS symptoms were included. Two groups were composed as group I (stabilized) and group II (nonstabilized). Read More

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http://dx.doi.org/10.3906/sag-1807-173DOI Listing
February 2019

Treatment and management of osteoporosis-pseudoglioma syndrome.

Authors:
Régis Levasseur

Expert Rev Endocrinol Metab 2008 May;3(3):337-348

a Rheumatology Department, Angers Teaching Hospital, Service de Rhumatologie et Pôle ostéo-articulaire, CHU d'Angers, Inserm U922, Faculté de Médecine d'Angers, 4 rue Larrey, 49460 Angers, France.

Osteoporosis-pseudoglioma syndrome (OPPG; MIM 259770) is a very rare genetic disorder with an autosomal recessive mode of inheritance, characterized by congenital or infancy-onset visual loss and skeletal fragility, diagnosed during childhood. This syndrome can lead to severe disability and chronic bone pain. Low-density lipoprotein receptor-related protein 5 (LRP5) is the gene mutated and inactivated in OPPG, and plays a pivotal role in bone accrual and skeletal remodeling by controlling bone formation through activators, such as Wnt proteins, or inhibitors, such as DKK1. Read More

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http://dx.doi.org/10.1586/17446651.3.3.337DOI Listing

Constitutional Syndrome, Ascites and Duodenal Thickening Presenting as Groove Pancreatitis.

Eur J Case Rep Intern Med 2018 21;5(3):000789. Epub 2018 Mar 21.

Department of Internal Medicine, Hospital Francesc de Borja, Gandia, Valencia, Spain.

Groove pancreatitis (GP) is a very infrequent subtype of chronic pancreatitis affecting the pancreatic-duodenal junction. It usually manifests in middle-aged men with a history of chronic alcoholism, though it has also been described in women and in individuals who do not consume alcohol. Even though the underlying etiology is unclear, chronic alcohol consumption is known to increase the viscosity of the pancreatic juice and exacerbate the inflammatory process. Read More

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http://dx.doi.org/10.12890/2017_000789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346956PMC

Mauriac Syndrome: A Rare Complication of Type 1 Diabetes Mellitus.

Eur J Case Rep Intern Med 2018 27;5(12):000969. Epub 2018 Dec 27.

Department of Internal Medicine, Centro Hospitalar Universitário de São João, E.P.E., Porto, Portugal.

Mauriac syndrome, first described in 1930, is typically diagnosed in young patients with poorly controlled type 1 diabetes mellitus and growth retardation, delayed puberty, Cushingoid features, hypercholesterolaemia and hepatomegaly. However, the sole presenting feature of Mauriac syndrome can be hepatic glycogenosis in both adults and children. The mainstay of treatment for hepatic glycogenosis is strict control of glucose levels, with an excellent prognosis with improved glycaemic control. Read More

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http://dx.doi.org/10.12890/2018_000969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346977PMC
December 2018

Mitochondrial Dysfunction in Skeletal Muscle of a Fibromyalgia Model: The Potential Benefits of Melatonin.

Int J Mol Sci 2019 Feb 11;20(3). Epub 2019 Feb 11.

Anatomy and Physiopathology Division, Department of Clinical and Experimental Sciences, University of Brescia, Viale Europa 11, 25123 Brescia, Italy.

Fibromyalgia syndrome (FMS) is considered a musculoskeletal disorder associated to other symptoms including chronic pain. Since the hypothesis of FMS etiogenesis is consistent with mitochondrial dysfunction and oxidative stress, we evaluated the pathophysiological correlation among these factors studying some proteins involved in the mitochondrial homeostasis. We focused our attention on the roles of peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1α), mitofusin2 (Mfn2), and coenzyme Q10 (CoQ10) in reserpine-induced myalgic (RIM) rats that manifest fibromyalgia-like chronic pain symptoms. Read More

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http://dx.doi.org/10.3390/ijms20030765DOI Listing
February 2019

Fibromyalgia syndrome: under-, over- and misdiagnosis.

Clin Exp Rheumatol 2019 Jan-Feb;37 Suppl 116(1):90-97. Epub 2019 Feb 8.

Division of Rheumatology, McGill University Health Centre, Quebec, Canada and Alan Edwards Pain Management Unit, McGill University Health Centre, Quebec, Canada.

Fibromyalgia syndrome (FM) is an enigma. During the past three decades, with the gradual acceptance of the validity of FM, it is variously under-, over and misdiagnosed. Evidence-based interdisciplinary guidelines have suggested a comprehensive clinical assessment to avoid this diagnostic conundrum. Read More

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February 2019
2 Reads

[Frailty progress and related factors in the elderly living in community: a prospective study].

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Feb;40(2):186-190

Center of Gerontology and Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.

To investigate frailty progress status and related factors in the elderly living in communities. A cohort of elderly people aged 65 and over in Pingyi community of Dujiangyan, Sichuan province, was established. Face-to-face questionnaire survey was conducted by trained interviewers. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.02.012DOI Listing
February 2019

Efficacy of Ultrasound-Guided Pulsed Radiofrequency for Recalcitrant Metatarsalgia .

J Am Podiatr Med Assoc 2018 Nov;108(6):532-534

Metatarsalgia is characterized by pain in the forefoot, which is associated with increased stress over the metatarsal head region. Despite the availability of a variety of conservative or surgical treatments for this condition, a few cases have demonstrated relapse or poor response to treatment. Pulsed radiofrequency (PRF) can provide pain relief in patients with diverse chronic conditions without causing neural injury. Read More

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http://dx.doi.org/10.7547/17-147DOI Listing
November 2018
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[The features of course of chronic abacterial prostatitis with inflammatory compoment in men of the first period of mature age depending on the somatotype. Part 1: the clinical characteristics].

Urologiia 2018 Dec(6):108-114

FGBOU VO Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky of the Ministry of Health of Russia, Krasnoyarsk, Russia.

Aim: to study the course of chronic abacterial prostatitis with the inflammatory component (CAPIC) depending on the somatotype in men of the first period of mature age taking complex treatment with a use of local and systemic ozone therapy.

Materials And Methods: A total of 306 men of asthenic, normostenic and pyknic somatotypes with CAPIC were followed-up. Along with standard therapy, all patients received systemic and local ozone therapy. Read More

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December 2018
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[Immediate and long-term effectiveness of combined application of magnetolaser therapy and red light in complex treatment of patients with chronic nonbacterial prostatitis].

Urologiia 2018 Dec(6):101-106

Department of Polyclinic Therapy and Medical Rehabilitation with the course of Additional Professional Education Federal State Educational Institution of Higher Education Altai State Medical University of the Ministry of Health of the Russian Federation, Barnaul, Russia.

The aim of the study was to increase the efficiency of complex treatment of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) with the combined effect of magnetolaser therapy (MLT) and red light.

Materials And Methods: We examined and included in the study 120 men with a verified diagnosis of CP/CPPS (III B), at the stage of exacerbation. By envelope method, patients were divided into two randomized groups. Read More

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December 2018
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A Rare Cause of Compression of the Suprascapular Nerve: The Paraglenoid Cyst.

J Orthop Case Rep 2018 Sep-Oct;8(5):40-42

Department of Orthopedic Surgery, Tunis Trauma Center, Ben Arous, Tunisia.

Introduction: The ductal syndromes of the shoulder combine all the compressive processes of the suprascapular nerve at the level of its passage in the spinoglenoid notch and this for several causes. The most common is a lesion of the labrum resulting in the formation of a cyst. These cysts are rare and often underestimated. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367289PMC
February 2019

Botulinum toxin A for pain reduction in pediatric patients with Parry-Romberg syndrome.

Pediatr Dermatol 2019 Feb 10. Epub 2019 Feb 10.

Pediatric Dermatology, Phoenix Children's Hospital, Phoenix, Arizona.

Parry-Romberg syndrome (PRS) is characterized by hemiatrophy of facial structures, including skin, subcutaneous fat, muscle, bone, and cartilage. Complications associated with PRS include headaches, seizures, and chronic facial pain. Protocol for the treatment of chronic facial pain is not clear; reports on the use of botulinum toxin A injections for pain reduction in adults but not in the pediatric/adolescent population are available. Read More

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http://dx.doi.org/10.1111/pde.13746DOI Listing
February 2019
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Functional neuroimaging in patients presenting with somatoform disorders: A model for investigating persisting symptoms after tick bites and post-treatment Lyme disease syndrome?

Med Mal Infect 2019 Feb 5. Epub 2019 Feb 5.

Institut de neurosciences de la Timone UMR7289, campus santé, Aix-Marseille université, 13005 Marseille, France; Pôle de psychiatrie, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France; Fondation FondaMental, 13005 Créteil, France.

Approximately 10% of patients presenting with Lyme disease experience fatigue, musculoskeletal pain, concentration disorders, or short-term memory deficits in the six months following treatment. This entity has been defined as post-Lyme disease syndrome or post-treatment Lyme disease syndrome. The pathophysiology of this syndrome is unknown, but neither persistence of the bacterium nor effectiveness of antibiotics are currently reported in the literature. Read More

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http://dx.doi.org/10.1016/j.medmal.2019.01.002DOI Listing
February 2019
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Change in gray matter volume and cerebral blood flow in patients with burning mouth syndrome.

J Oral Pathol Med 2019 Feb 8. Epub 2019 Feb 8.

Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, Seoul, Korea.

Background: The purpose of this study was to evaluate alterations in gray matter volume (GMV) and cerebral blood flow (CBF) using structural MRI and arterial spin labeling (ASL) perfusion MRI, respectively, in burning mouth syndrome (BMS) patients.

Methods: We prospectively enrolled 12 patients with BMS and 14 healthy controls. Volumetric T1-weighted magnetization-prepared rapid gradient-echo imaging and pseudo-continuous ASL were performed to obtain GMV and CBF, respectively. Read More

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http://doi.wiley.com/10.1111/jop.12838
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http://dx.doi.org/10.1111/jop.12838DOI Listing
February 2019
2 Reads

Chronic lower extremity wounds in a patient with Klippel Trenaunay syndrome.

J Vasc Surg Cases Innov Tech 2019 Mar 28;5(1):45-48. Epub 2019 Jan 28.

Department of Surgery, Atlantic Health System Morristown Medical Center, Morristown, NJ.

Klippel-Trenaunay syndrome is a rare disorder consisting of the triad of vascular and/or lymphatic malformations, capillary malformations, and soft tissue or bony hypertrophy. Symptom control is the mainstay of treatment for these patients, with many of the symptoms never fully being relieved. In this case report, we present the case of a 46-year-old man with chronic lower extremity ulcerations unresponsive to wound care therapy. Read More

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http://dx.doi.org/10.1016/j.jvscit.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355325PMC
March 2019
1 Read

Current management strategies for the pain of elderly patients with burning mouth syndrome: a critical review.

Biopsychosoc Med 2019 31;13. Epub 2019 Jan 31.

1Department of Psychosomatic Dentistry, Graduate School of Medical and Dental sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo, 113-8549 Japan.

Burning Mouth Syndrome (BMS), a chronic intraoral burning sensation or dysesthesia without clinically evident causes, is one of the most common medically unexplained oral symptoms/syndromes. Even though the clinical features of BMS have been astonishingly common and consistent throughout the world for hundreds of years, BMS remains an enigma and has evolved to more intractable condition. In fact, there is a large and growing number of elderly BMS patients for whom the disease is accompanied by systemic diseases, in addition to aging physical change, which makes the diagnosis and treatment of BMS more difficult. Read More

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http://dx.doi.org/10.1186/s13030-019-0142-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357406PMC
January 2019
1 Read

[Sensitivity and Specificity of the Reizdarm-Fragebogen].

Psychother Psychosom Med Psychol 2019 Feb 7. Epub 2019 Feb 7.

Abt. Psychosomatik und Verhaltenstherapie, Rehazentrum Seehof der Deutschen Rentenversicherung, Teltow.

Background: The Reizdarm-Fragebogen (RDF) is the first German questionnaire to assess subjectively perceived symptom severity of irritable bowel syndrome (IBS). Thus far, this was only possible in the context of a medical examination by a practitioner. The goal of the current study was to assess differences in RDF scores among IBS patients and other clinical and non-clinical populations. Read More

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http://dx.doi.org/10.1055/a-0834-6207DOI Listing
February 2019
1 Read

Effects of CPEB1 in the anterior cingulate cortex on visceral pain in mice.

Brain Res 2019 Feb 4. Epub 2019 Feb 4.

Department of Pharmacology, School of Pharmacy, and Precision Pharmacy & Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710032, China. Electronic address:

Patients with irritable bowel syndrome suffer from chronic visceral pain, and in some of them, this is accompanied by anxiety comorbidity. Cytoplasmic polyadenylation element binding protein 1 (CPEB1) mediates the cytoplasmic polyadenylation of mRNAs and facilitates their translation. Our previous studies have shown that CPEB1 knockdown in the amygdala exerts anxiolytic but not analgesic effects in a mouse model of inflammatory pain. Read More

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http://dx.doi.org/10.1016/j.brainres.2019.02.001DOI Listing
February 2019
1 Read

The utility of droperidol in the treatment of cannabinoid hyperemesis syndrome.

Clin Toxicol (Phila) 2019 Feb 7:1-5. Epub 2019 Feb 7.

a Austin Clinical School , University of Melbourne , Melbourne , Australia.

Introduction: Cannabinoid hyperemesis syndrome (CHS) can be characterized by recurrent paroxysmal episodes of intractable nausea and vomiting, abdominal pain, and compulsive hot showers/baths with symptom relief, on the background of chronic cannabis use. We reported the use of droperidol in the management of CHS.

Methods: We performed a retrospective review of electronic medical records of Emergency Department presentations to a single tertiary level metropolitan hospital between January 2006 and December 2016 using search keywords: "cannabis", "cannabinoid", "cannabis", "hyperemesis", and "droperidol". Read More

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http://dx.doi.org/10.1080/15563650.2018.1564324DOI Listing
February 2019

Joint Hypermobility Among Female Patients Presenting with Chronic Myofascial Pelvic Pain.

PM R 2019 Feb 6. Epub 2019 Feb 6.

Department of Obstetrics and Gynecology, Denver Health Medical Center, Denver, CO.

Background: Female chronic pelvic pain is estimated to affect up to 24% of adult women, many of whom have a component of myofascial pelvic pain. Although an association of joint hypermobility and pelvic pain has been hypothesized, limited data are available that estimate the prevalence of joint hypermobility in this population.

Objective: To estimate the prevalence of generalized hypermobility spectrum disorder (G-HSD) among female patients with chronic myofascial pelvic pain and examine the association between G-HSD and other frequent pelvic pain-associated complaints. Read More

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http://dx.doi.org/10.1002/pmrj.12131DOI Listing
February 2019
2 Reads

Understanding sexual pain in endometriosis.

Minerva Ginecol 2019 Feb 6. Epub 2019 Feb 6.

Department of Gynaecology and Obstetrics, Geneva University Hospitals, Geneva, Switzerland.

Sexual dysfunctions, particularly sexual pain, are common in adult women of all ages. In patients with endometriosis, a chronic gynaecological pain condition affecting women of reproductive age, sexual pain is the third most common symptom. Multiple biological factors are involved in endometriosis-related sexual pain including tissue damage, inflammation, hormonal changes, alterations within the peripheral and central nervous system and pelvic floor muscle dysfunctions. Read More

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http://dx.doi.org/10.23736/S0026-4784.19.04379-XDOI Listing
February 2019
1 Read

Emergency Department and Radiological Cost of Delayed Diagnosis of Cannabinoid Hyperemesis.

J Addict 2019 1;2019:1307345. Epub 2019 Jan 1.

St. Joseph Regional Medical Center, Mishawaka, IN 46545, USA.

Chronic cannabis use has become prevalent with decriminalization, medical prescription, and recreational legalization in numerous US states. With this increasing incidence of chronic cannabis use a new clinical syndrome has become apparent in emergency departments and hospitals across the country, termed Cannabinoid Hyperemesis (CH). CH has been described as cyclical vomiting and abdominal pain in the setting of chronic cannabis use, which is often temporarily relieved by hot showers. Read More

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http://dx.doi.org/10.1155/2019/1307345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339733PMC
January 2019

Salvage therapy with burst spinal cord stimulation for chronic pancreatitis: A case report.

Pain Pract 2019 Feb 5. Epub 2019 Feb 5.

Department of Anesthesiology, Pain Clinic. Hospital Regional Universitario de Málaga. Avda, Carlos Haya s/n. 29010. Málaga.

Pain associated with chronic pancreatitis is often difficult to treat. On many occasions, interventional techniques may be necessary. In recent years, spinal cord stimulation techniques have been used successfully in the management of these patients. Read More

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http://dx.doi.org/10.1111/papr.12771DOI Listing
February 2019
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The role of Nav1.7 in human nociceptors: insights from human iPS cell-derived sensory neurons of erythromelalgia patients.

Pain 2019 Jan 31. Epub 2019 Jan 31.

Institute of Physiology, Uniklinik RWTH Aachen, 52074 Aachen, Germany.

The chronic pain syndrome inherited erythromelalgia (IEM) is attributed to mutations in the voltage-gated sodium channel (Nav) 1.7. Still, recent studies targeting Nav1. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001511DOI Listing
January 2019
1 Read

Suspected adverse effects after human papillomavirus vaccination: a temporal relationship.

Immunol Res 2019 Feb 5. Epub 2019 Feb 5.

Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, 390-8621, Japan.

In Japan, a significant number of adolescent girls complained unusual symptoms after human papillomavirus (HPV) vaccination, and the vast majority of them were initially diagnosed as having psychiatric illness because of the absence of pathologic findings, radiological images and specific abnormalities in laboratory test results. Later, these symptoms were supposed to be adverse effects after HPV vaccination, and the recommendation for HPV vaccination was withdrawn by Japanese Ministry of Public Health, Labour and Welfare 4 years and 9 months ago. However, a causal link has not been demonstrated between HPV vaccination and the development of these symptoms. Read More

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http://link.springer.com/10.1007/s12026-018-9063-y
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http://dx.doi.org/10.1007/s12026-018-9063-yDOI Listing
February 2019
2 Reads

[Complex regional pain syndrome (CRPS) : An update].

Authors:
V Dimova F Birklein

Anaesthesist 2019 Feb;68(2):115-128

Klinik und Poliklinik für Neurologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55101, Mainz, Deutschland.

The acute phase of complex regional pain syndrome (CRPS) is pathophysiologically characterized by an activation of the immune system and its associated inflammatory response. During the course of CRPS, central nervous symptoms like mechanical hyperalgesia, loss of sensation, and body perception disorders develop. Psychological factors such as pain-related anxiety and traumatic events might have a negative effect on the treatment outcome. Read More

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http://dx.doi.org/10.1007/s00101-019-0539-5DOI Listing
February 2019
1 Read

The frequency, clinical course, and health related quality of life in adults with Gilbert's syndrome: a longitudinal study.

BMC Gastroenterol 2019 Feb 4;19(1):22. Epub 2019 Feb 4.

Faculty of Medicine, Misr University for Science and Technology, Cairo, Egypt.

Background: Gilbert syndrome (GS) is an autosomal recessive inherited disorder of bilirubin glucuronidation which has not been investigated in Egypt. This longitudinal study investigated the frequency, clinical course, genetic profile and health related quality of life in Egyptian adults.

Methods: An initial cross-sectional study was conducted to assess the frequency of Gilbert syndrome among Egyptian adults. Read More

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http://dx.doi.org/10.1186/s12876-019-0931-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360704PMC
February 2019
2 Reads

Novel Treatment of Experimental Autoimmune Prostatitis by Nanoparticle-Conjugated Autoantigen Peptide T2.

Inflammation 2019 Feb 4. Epub 2019 Feb 4.

Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu Province, China.

The exact etiology and pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still unknown, as a result, available therapeutic options for patients are far from satisfactory. Therefore, there is a need to develop a valid therapeutic approach that can ameliorate the manifestations of CP/CPPS. Fifty male C57BL/6 mice were randomly divided into five groups of ten mice each. Read More

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http://dx.doi.org/10.1007/s10753-019-00968-5DOI Listing
February 2019
2 Reads
1.921 Impact Factor

Unusual case of hypotenar Hammer Syndrome and carpal tunnel syndrome association.

Acta Biomed 2018 Dec 20;90(1-S):158-161. Epub 2018 Dec 20.

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Background And Aim Of The Work: Hypothenar Hammer Syndrome is a relatively rare disease process caused by repetitive stress or injury to the hypothenar eminence leading to chronic injury to the ulnar artery. Our study reports an unusual case.

Methods: A 57 years old Plumber presented in April 2016 with a history of constant pain and recurrent paresthesia involving the fingers of the right hand for several months, over the previous 1 year, his hand had become more intolerant of exposure to cold temperatures. Read More

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http://dx.doi.org/10.23750/abm.v90i1-S.8016DOI Listing
December 2018
1 Read

Cav3.2 calcium channel inhibition: a new target for colonic hypersensitivity associated with low-grade inflammation.

Br J Pharmacol 2019 Feb 4. Epub 2019 Feb 4.

Université Clermont Auvergne, INSERM, NEURO-DOL Basics & Clinical Pharmacology of Pain, F-63000, Clermont-Ferrand, France.

Background And Purpose: Abdominal pain associated with low-grade inflammation is frequently encountered in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) during the remission phase. Current treatments are generally weakly effective. Therefore, new therapeutic approaches are needed. Read More

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http://doi.wiley.com/10.1111/bph.14608
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http://dx.doi.org/10.1111/bph.14608DOI Listing
February 2019
5 Reads

A Rare Case of Spontaneous Tumor Lysis Syndrome in Idiopathic Primary Myelofibrosis.

Am J Case Rep 2019 Feb 3;20:146-150. Epub 2019 Feb 3.

Department of Hemato-Oncology, Chosun University Hospital, Gwangju, South Korea.

BACKGROUND Tumor lysis syndrome (TLS) is an oncologic emergency resulting from the massive destruction of tumor cells after cytotoxic chemotherapy for chemosensitive malignancies with a high tumor burden. Its clinical manifestations include severe electrolyte disturbances, metabolic acidosis, acute renal failure secondary to urate deposition in the kidney, heart, and skeletal muscle, and nervous system dysfunction. We report an extremely rare case of spontaneous TLS (STLS) in idiopathic primary myelofibrosis (PMF). Read More

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http://dx.doi.org/10.12659/AJCR.912682DOI Listing
February 2019
2 Reads

Ulnar Artery Thrombosis Presented with Unilateral Raynaud's Phenomenon Findings After Long-Term Intensive Handicraft Activity: Hypothenar Hammer Syndrome.

Ann Vasc Surg 2019 Jan 31. Epub 2019 Jan 31.

Department of Physical Therapy and Rehabilitation of University of Health Sciences, Ankara Health Application and Research Center, Ankara, Turkey.

Background: Hypothenar Hammer Syndrome (HHS) is an uncommon vascular syndrome of upper extremity. HHS should be considered in patients who are presented with digital ischemia. Distal ulnar artery compression at the level of Guyon's canal with trauma result in thrombus or aneurysm. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.10.034DOI Listing
January 2019
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Differences in neuronal representation of mental rotation in CRPS patients and healthy controls.

J Pain 2019 Jan 30. Epub 2019 Jan 30.

Functional Imaging Unit, Center for Diagnostic Radiology, University of Greifswald, Germany. Electronic address:

Spatial integration of parts of the body is impaired in patients with complex regional pain syndrome (CRPS). Since the training of mental rotation (MR) has been shown to be among the effective therapy strategies for CRPS, impairment of MR is also important for the pathophysiological understanding of CRPS. The aim of this study was to evaluate whether differences in neural representation of MR occur between CRPS patients and healthy controls. Read More

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http://dx.doi.org/10.1016/j.jpain.2019.01.330DOI Listing
January 2019
1 Read

Muscle pain in mitochondrial diseases: a picture from the Italian network.

J Neurol 2019 Feb 2. Epub 2019 Feb 2.

Neurological Clinic, University of Pisa, Pisa, Italy.

Muscle pain may be part of many neuromuscular disorders including myopathies, peripheral neuropathies and lower motor neuron diseases. Although it has been reported also in mitochondrial diseases (MD), no extensive studies in this group of diseases have been performed so far. We reviewed clinical data from 1398 patients affected with mitochondrial diseases listed in the database of the "Nation-wide Italian Collaborative Network of Mitochondrial Diseases", to assess muscle pain and its features. Read More

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http://link.springer.com/10.1007/s00415-019-09219-x
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http://dx.doi.org/10.1007/s00415-019-09219-xDOI Listing
February 2019
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Factors affecting quality of life in children and adolescents with hypermobile Ehlers-Danlos syndrome/hypermobility spectrum disorders.

Am J Med Genet A 2019 Jan 31. Epub 2019 Jan 31.

Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Hypermobile Ehlers-Danlos syndrome (hEDS) is a hereditary disorder of connective tissue, often presenting with complex symptoms can include chronic pain, fatigue, and dysautonomia. Factors influencing functional disability in the pediatric hEDS population are incompletely studied. This study's aims were to assess factors that affect quality of life in children and adolescents with hEDS. Read More

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http://doi.wiley.com/10.1002/ajmg.a.61055
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http://dx.doi.org/10.1002/ajmg.a.61055DOI Listing
January 2019
6 Reads

Visual Imagery: A Tool to Explore the Impact of Burning Mouth Syndrome.

J Oral Facial Pain Headache 2019 Winter;33(1):e8-e14

Aims: To investigate how photographic images (Pain Cards) co-created by an artist and chronic pain patients could be used in groups of patients with burning mouth syndrome to facilitate characterization of their pain and its impact on quality of life.

Methods: Ten groups of patients with burning mouth syndrome attending a 2.5-hour information session in a facial pain unit were presented with 54 Pain Cards put in a random order on a table. Read More

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http://dx.doi.org/10.11607/ofph.2095DOI Listing
February 2019

Characteristics of women with chronic pelvic pain referred to physiotherapy treatment after multidisciplinary assessment: a cross-sectional study.

Scand J Pain 2019 Jan 31. Epub 2019 Jan 31.

Institute of Physiotherapy, OsloMet - Oslo Metropolitan University, Oslo, Norway.

Background and aims Chronic pelvic pain (CPP) in women is a complex condition that can seriously impact health and quality of life. Clinical guidelines for CPP place great demands on healthcare professionals, as they require both specialized knowledge about the pelvic area and knowledge of the mechanisms of chronic pain. To ensure best possible assessment and treatment of these women it is important to bring about more knowledge of the special CPP features. Read More

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http://dx.doi.org/10.1515/sjpain-2018-0308DOI Listing
January 2019
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Clinical effects of pulsed radiofrequency to the thoracic sympathetic ganglion versus the cervical sympathetic chain in patients with upper-extremity complex regional pain syndrome: A retrospective analysis.

Medicine (Baltimore) 2019 Feb;98(5):e14282

Department of Anesthesiology and Pain Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Pulsed radiofrequency (PRF) to the thoracic sympathetic ganglion (TSG PRF) or to the cervical sympathetic chain (CSC PRF) can be performed to overcome transient effects of single sympathetic blocks in patients with upper-extremity complex regional pain syndrome (CRPS).We retrospectively compared the clinical effects of TSG PRF and CSC PRF. Seven TSG PRF cases and 10 CSC PRF cases were enrolled in the present analysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014282DOI Listing
February 2019
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Pharmacotherapy of chronic pancreatitis in terms of current clinical recommendations.

Ter Arkh 2018 Aug;90(8):81-85

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University), Moscow, Russia.

The article reflects the main positions of the latest Russian and pan-European clinical recommendations on the diagnosis and treatment of chronic pancreatitis (CP), devoted to the pharmacotherapy of this disease. The main objectives of pharmacotherapy for CP are to reduce or arrest pain abdominal syndrome and prevent or compensate for functional pancreatic insufficiency. Read More

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http://dx.doi.org/10.26442/terarkh201890881-85DOI Listing
August 2018
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Transforaminal Epiduroscopy in Patients with Failed Back Surgery Syndrome.

Pain Physician 2019 Jan;22(1):89-95

Pain Clinic, Hospital Universitario Sanitas La Moraleja, Madrid, Spain; Consultores en Dolor, Madrid, Spain.

Background: Epiduroscopy is a useful diagnostic and therapeutic tool for managing failed back surgery syndrome (FBSS). The conventional approach is via either the sacral hiatus or the interlaminar. Major causes of FBSS include epidural fibrosis, disc herniation, and stenosis. Read More

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January 2019

The Oslo University Hospital Pain Registry: development of a digital chronic pain registry and baseline data from 1,712 patients.

Scand J Pain 2019 Jan 30. Epub 2019 Jan 30.

Advisory Unit on Pain Management Health Region South-East, Oslo, Norway.

Background and aims Chronic pain is a leading cause to years lived with disability worldwide. However, few of the interventions used in pain medicine have proven efficacy, and evidence from the existing studies may not be valid for the general pain population. Therefore, it is of utmost need that we describe chronic pain conditions in their most relevant aspects, their various guises, as well as the real world outcomes of our clinical interventions. Read More

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http://dx.doi.org/10.1515/sjpain-2017-0160DOI Listing
January 2019
2 Reads