129,741 results match your criteria Chronic Laryngitis Infectious or Allergic


Different Psychosocial Factors Are Associated with Seasonal and Perennial Allergies in Adults: Cross-Sectional Results of the KORA FF4 Study.

Int Arch Allergy Immunol 2019 Apr 24:1-11. Epub 2019 Apr 24.

Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München, Augsburg, Germany,

Background: Psychosocial factors are supposed to play a central role in the development of allergic diseases. Associations with seasonal and perennial forms of allergies have not been investigated, yet.

Objectives: The aim of the study was to investigate the associations of psychosocial factors (social status, depression, generalized anxiety, psychosocial stress, Type-D personality) with seasonal, perennial, and other forms of allergies in adults. Read More

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/499042
Publisher Site
http://dx.doi.org/10.1159/000499042DOI Listing
April 2019
1 Read

Food allergy knowledge, attitudes and their determinants among restaurant staff: A cross-sectional study.

PLoS One 2019 24;14(4):e0214625. Epub 2019 Apr 24.

Family Medicine and Primary Care, Lee Kong Chian School of Medicine, Mandalay, Nanyang Technological University Singapore, Singapore, Singapore.

Background: There is wide international variation regarding food allergy knowledge among restaurant staff. Further, attitudes towards food allergy remain under-researched. Insights into the independent determinants of knowledge and attitudes are limited due to lacking mutual statistical adjustment for determinants/confounders in the vast majority of prior studies. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214625PLOS

The development of inflammatory arthritis and enthesitis in patients on dupilumab: a case series.

Br J Dermatol 2019 Apr 24. Epub 2019 Apr 24.

St. John's Institute of Dermatology, Guy's and St, Thomas' Hospital NHS Trust, Great Maze Pond, London, SE1 9RT.

Dupilumab (Dupixent , Sanofi), a fully human monoclonal antibody that blocks interleukin (IL)-4 and IL-13 signaling, is the first biologic approved in the UK for adult patients with moderate-to-severe atopic dermatitis (AD). In phase III studies, dupilumab was an effective treatment with 44-51% of patients achieving at least 75% improvement in Eczema Area and Severity Index (EASI). To date, dupilumab has been well tolerated; common adverse reactions reported from phase III data include injection-site reactions (8-19%), allergic conjunctivitis (3-19%) and oral herpes (2-5%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.18031DOI Listing

Effect of Lavandula dentata extract on Ovalbumin-induced Asthma in Male Guinea Pigs.

Braz J Biol 2019 Apr 18. Epub 2019 Apr 18.

Department of Biology, Faculty of Science, Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia.

Asthma is an inflammatory disease of the lungs, and it causes oxidative stress. Lavandula dentata is an aromatic herb with anti-oxidative and anti-inflammatory activities. This study examined the activity of L. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/1519-6984.191485DOI Listing

Isotretinoin in Severe Peanut- and Soy-Allergic Patients: Is it Safe or Not?

J Investig Allergol Clin Immunol 2019 Apr;29(2):146-148

KU Leuven Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Group, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18176/jiaci.0352DOI Listing

Is Quantitative sIgE Serology Suitable for Distinguishing Between Silent Sensitization and Allergic Rhinitis to Dermatophagoides pteronyssinus?

J Investig Allergol Clin Immunol 2019 Apr;29(2):124-131

Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-University Hospital, Munich, Germany.

Background And Objective: An increasing number of studies have recently discussed whether provocation tests might be replaced by specific IgE serology in patients sensitized to airborne allergens. Objective: Our study aimed to analyze the concordance between a nasal provocation test with Dermatophagoides pteronyssinus and specific IgE measurements based on real-life data.

Methods: We retrospectively analyzed concordance between the result of the provocation test and the IgE titer for house dust mite components and extracts in 223 patients with proven sensitization to D pteronyssinus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18176/jiaci.0299DOI Listing

Loquat (Eriobotrya japonica) allergy, including anaphylaxis, is induced by a Bet v1 homolog.

J Investig Allergol Clin Immunol 2019 Apr 24. Epub 2019 Apr 24.

Faculty of Education, Shitennoji University, Habikino, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18176/jiaci.0406DOI Listing

Asthma phenotypes and associated comorbidities in a large cohort of adolescents in Israel.

J Asthma 2019 Apr 24:1-14. Epub 2019 Apr 24.

a Medical Corps, IDF , Israel.

Objectives: Asthma is a multifactorial, heterogeneous, complex and common chronic respiratory disease driven by diverse mechanisms. Although asthma presents various clinical forms with different levels of severity, it is unclear whether asthma severities are a consequence of disease management or varied etiologies. We sought to investigate this question. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02770903.2019.1604743DOI Listing

Clinical Efficacy of Allergen-Specific Immunotherapy from Patient and Physician Perspectives.

Yonsei Med J 2019 May;60(5):446-453

Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.

Purpose: Allergen-specific immunotherapy (AIT) is the only curative treatment for allergic diseases, but a few allergic patients receive AIT. In this multicenter cross-sectional study, we aimed to explore patient and physician perspectives on AIT through a questionnaire survey.

Materials And Methods: Allergic patients who received subcutaneous immunotherapy for at least 1 year were asked to answer a questionnaire developed by an expert panel of allergen and immunotherapy workgroup in Korea. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3349/ymj.2019.60.5.446DOI Listing

The Role of Interleukin-9 in Cancer.

Pathol Oncol Res 2019 Apr 23. Epub 2019 Apr 23.

Department of Microbiology, Immunology & Pathology, Des Moines University College of Osteopathic Medicine, Des Moines, Iowa, 50312, USA.

Interluekin-9 (IL-9) is produced predominantly by helper T cells such as Th2 and Th9 cells. It normally functions through the activation of a JAK/STAT pathway and plays a critical role in immunity and the pathogenesis of cancer. In cancer, it yields different responses depending on the cancer cell line involved. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12253-019-00665-6
Publisher Site
http://dx.doi.org/10.1007/s12253-019-00665-6DOI Listing
April 2019
1 Read

[Perspectives for nationwide pollen monitoring in Germany].

Authors:

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2019 Apr 23. Epub 2019 Apr 23.

Allergenic pollen are natural, biological airborne particles and the main cause of allergic respiratory diseases. The measurement of allergenic pollen is a required measure in preventive healthcare and indicates changes in the pollen spectrum as to be expected in the context of climate change.The only nationwide pollen measuring network in Germany is operated by the Foundation German Pollen Information Service, however, its continuity and further development (a hybrid system with manual and automated pollen traps) are not financially guaranteed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00103-019-02940-yDOI Listing

Effect of Low-Level Laser Therapy (LLLT) in Pulmonary Inflammation in Asthma Induced by House Dust Mite (HDM): Dosimetry Study.

Int J Inflam 2019 21;2019:3945496. Epub 2019 Mar 21.

Post-Graduate Program in Biophotonics Applied to Health Sciences, University Nove de Julho (UNINOVE), Sao Paulo, Brazil.

Asthma is characterized by chronic inflammation in the airways. Several models have been proposed for the discovery of new therapies. Low-Level Laser Therapy (LLLT) is relatively new and effective, very low cost, with no side effects. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/iji/2019/3945496/
Publisher Site
http://dx.doi.org/10.1155/2019/3945496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448342PMC
March 2019
1 Read

Risk Assessment of Drometrizole, a Cosmetic Ingredient used as an Ultraviolet Light Absorber.

Toxicol Res 2019 Apr 15;35(2):119-129. Epub 2019 Apr 15.

BK21Plus Team, College of Pharmacy, The Catholic University of Korea, Bucheon, Korea.

As the use of cosmetics has greatly increased in a daily life, safety issues with cosmetic ingredients have drawn an attention. Drometrizole [2-(2'-hydroxy-5'-methylphenyl)benzotriazole] is categorized as a sunscreen ingredient and is used in cosmetics and non-cosmetics as a UV light absorber. No significant toxicity has been observed in acute oral, inhalation, or dermal toxicity studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5487/TR.2019.35.2.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467354PMC

The complex pathophysiology of allergic rhinitis: scientific rationale for the development of an alternative treatment option.

Allergy Asthma Clin Immunol 2019 16;15:24. Epub 2019 Apr 16.

5Department of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.

Allergic rhinitis (AR) poses a global health problem and can be challenging to treat. Many of the current symptomatic treatments for AR have been available for decades, yet there has been little improvement in patient quality of life or symptom burden over the years. In this review, we ask why this might be and explore the pathophysiological gaps that exist within the various AR treatment classes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13223-018-0314-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469109PMC

Vaccine safety surveillance in Canada: Reports to CAEFISS, 2013-2016.

Can Commun Dis Rep 2018 Sep 6;44(9):206-214. Epub 2018 Sep 6.

CAEFISS: Canadian Adverse Events Following Immunization Surveillance System, Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, ON.

Background: Canada has one of the strongest vaccine safety surveillance systems in the world. This system includes both passive surveillance of all vaccines administered and active surveillance of all childhood vaccines.

Objectives: To provide 1) a descriptive analysis of the adverse events following immunization (AEFI) reports for vaccines administered in Canada, 2) an analysis of serious adverse events (SAEs) and 3) a list of the top ten groups of vaccines with the highest reporting rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14745/ccdr.v44i09a04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449118PMC
September 2018

Clinical Characteristics of Severe Refractory Asthma Associated with the Effectiveness of Bronchial Thermoplasty.

Acta Med Okayama 2019 Apr;73(2):155-160

Department of Respiratory Medicine, Okayama Medical Center, Okayama 701-1192,

We investigated the clinical characteristics of refractory asthma associated with the effectiveness of bronchial thermoplasty (BT). We retrospectively evaluated data from 10 patients who underwent BT between June 2016 and December 2017 at Okayama Medical Center. The following were measured before and 6 months post-BT: forced expiratory volume in 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18926/AMO/56651DOI Listing
April 2019
1 Read

Amelioration of allergic asthma by Ziziphora clinopodioides via upregulation of aquaporins and downregulation of IL4 and IL5.

Respir Physiol Neurobiol 2019 Apr 20. Epub 2019 Apr 20.

University College of Pharmacy, University of the Punjab, old campus, Lahore, Pakistan.

Ziziphora clinopodioides has been frequently used as an anti asthmatic plant in traditional medication. Recent work explores the anti-asthmatic activity of Z. clinopodioides in allergen-induced asthmatic mice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.resp.2019.04.005DOI Listing

Acute ST-Segment Elevation Myocardial Infarction Following Intramuscular Diclofenac: A Case of Kounis Syndrome.

J Emerg Med 2019 Apr 20. Epub 2019 Apr 20.

Department of Emergency Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

Background: Kounis syndrome (allergic myocardial infarction) is the rare occurrence of systemic anaphylaxis with spontaneous electrocardiographic changes in response to an exogenous agent. Often the syndrome is caused by a drug reaction involving drugs such as non-steroidal anti-inflammatory drugs, antibiotics, or opioids. There are a few reported cases in the literature regarding diclofenac-induced Kounis syndrome, and little is known about the management of this clinical entity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jemermed.2019.03.026DOI Listing

A network-based approach for identifying suitable biomarkers for oral immunotherapy of food allergy.

BMC Bioinformatics 2019 Apr 23;20(1):206. Epub 2019 Apr 23.

TNO, PO Box 360, 3700, AJ, Zeist, The Netherlands.

Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, concerns with regards to safety and long-term efficacy of OIT remain. There is a need to identify biomarkers that predict, monitor and/or evaluate the effects of OIT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-019-2802-9DOI Listing

Association between Dipeptidyl Peptidase-4 Inhibitors and Allergic Rhinitis in Asian Patients with Diabetes.

Int J Environ Res Public Health 2019 Apr 12;16(8). Epub 2019 Apr 12.

Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung 404, Taiwan.

In this retrospective study, we attempted to evaluate the association between dipeptidyl peptidase-4 (DPP-4) inhibitors and allergic rhinitis in patients with diabetes. We analyzed the Longitudinal Health Insurance Database 2000 subdatabase. Our study population included patients with type 2 diabetes (ICD-9-CM 250) between 2009 and 2012, and the study groups were DPP-4 inhibitor users and nonusers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph16081323DOI Listing

Resolvin D2 elevates cAMP to increase intracellular [Ca] and stimulate secretion from conjunctival goblet cells.

FASEB J 2019 Apr 23:fj201802467R. Epub 2019 Apr 23.

Schepens Eye Research Institute, Massachusetts Eye and Ear-Harvard Medical School, Boston, Massachusetts, USA.

Under physiologic conditions, conjunctival goblet cells (CGCs) secrete mucins into the tear film to preserve ocular surface homeostasis. Specialized proresolving mediators (SPMs), like resolvins (Rvs), regulate secretion from CGCs and actively terminate inflammation. The purpose of this study was to determine if RvD2 stimulated mucin secretion and to investigate the cellular signaling components. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201802467RDOI Listing

[MASK (Mobile Airways Sentinel Network). ARIA's comprehensive solution for mobile app for the multimorbidity of allergic rhinitis and asthma].

Rev Alerg Mex 2019 Jan-Mar;66(1):140-146

Médica Sur, Centro de Excelencia en Asma y alergia, Ciudad de México, México.

The vast majority of patients with allergic rhinitis (AR) do not receive the proper management which is recommended by the guidelines, but they frequently self-medicate. MASK (Mobile Airways Sentinel Network) is an integral part of a project that is supported by the European Union against chronic diseases and focused on active and healthy aging. MASK represents the third phase of ARIA (Allergic Rhinitis and its Impact on Asthma), in which, by using a mobile application in a smart device, the objective is to guide the patient in the control of his/her multi-morbidity, AR and/or allergic conjunctivitis (AC) and/or asthma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.578DOI Listing

[Asthma of difficult control linked to pulmonary thromboembolism and bronchopulmonary aspergillosis].

Rev Alerg Mex 2019 Jan-Mar;66(1):128-131

Universidad de Antioquia, Grupo de Alergología Clínica y Experimental, Antioquia, Colombia.

Background: Inflammation caused by chronic diseases and the constant use of systemic corticosteroids could be linked to the increased incidence of venous thromboembolic disease.

Clinical Case: A 47 year-old man with severe asthma of difficult control and allergic bronchopulmonary aspergillosis who, although the treatment was optimal, continued to have recurrent exacerbations and the need for systemic corticosteroids. He had edema in his left leg. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.352DOI Listing

[Anaphylaxis in a lactating infant who is allergic to cow's milk protein].

Rev Alerg Mex 2019 Jan-Mar;66(1):123-127

Universidad de Antioquia, Grupo de Alergología Clínica y Experimental, Antioquia, Colombia.

Background: Allergy to cow's milk protein is a common problem in children. The clinical manifestations of the reactions that are mediated by IgE are varied and the anaphylactic reactions can be life-threatening.

Clinical Case: A girl at an age of four months and a half that, five minutes after consuming cereal with cow's milk, had rashes in the perioral area and extensive pruritic micropapular lesions associated with vomit and inspiratory stridor. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.350DOI Listing
April 2019
1 Read

Adverse immune reactions and non-immune medications for perioperative use.

Rev Alerg Mex 2019 Jan-Mar;66(1):99-114

Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Centro Regional de Alergia e Inmunología Clínica, Monterrey, Nuevo León, México.

Reactions to medications can occur through a mechanism mediated by immunoglobulin or otherwise, not both. Drug allergy is a type of adverse reaction to the drug and comprises a range of hypersensitivity reactions mediated by different immunological mechanisms with diverse clinical manifestations. A rate of 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.541DOI Listing

[Cross-sectional survey about the prevalence of allergic rhinitis in Argentina: Study PARA].

Rev Alerg Mex 2019 Jan-Mar;66(1):55-64

Asociación Argentina de Alergia e Inmunología Clínica, Buenos Aires, Argentina.

Background: There are very few studies about the prevalence of allergic rhinitis in Argentina.

Objective: To determine the prevalence of allergic rhinitis in a population of inhabitants between the ages of 5 and 44 in Argentina.

Methods: A cross-sectional national study in which a self-reported questionnaire was used. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.543DOI Listing

[Diagnosis of allergic sensitization in patients with allergic rhinitis and asthma in a tropical environment].

Rev Alerg Mex 2019 Jan-Mar;66(1):44-54

Clínica El Ávila, Servicio de Alergia e Inmunología Clínica, Caracas, Venezuela.

Background: Few studies in tropical developing countries have utilized molecular diagnosis to characterize allergen-specific responses to aeroallergens.

Objective: To investigate the in vivo and in vitro responses of IgE antibodies to inhalant allergens in allergic patients with rhinitis and/or asthma.

Methods: A prospective study in which patients with allergic rhinitis and/or asthma were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.570DOI Listing

[Sensitivity and specificity of the modified epicutaneous patch test in the diagnosis of respiratory allergy to Dermatophagoides pteronyssinus].

Rev Alerg Mex 2019 Jan-Mar;66(1):38-43

Universidad Autónoma de Puebla, Hospital Universitario de Puebla, Servicio de Alergia e Inmunología Clínica, Puebla, Puebla, México.

Background: The skin prick test is recognized as the gold standard for the specific diagnosis of allergy.

Objective: To determine the sensitivity and specificity of the epicutaneous patch test that has been modified for the diagnosis of respiratory allergy to Dermatophagoides pteronyssinus.

Methods: An observational, interpretative, prolective, and transversal study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.533DOI Listing

[Evaluation of diagnostic and management concepts of anaphylaxis in non-allergist physicians in Colombia].

Rev Alerg Mex 2019 Jan-Mar;66(1):18-26

Universidad de Antioquía, Grupo de Alergología Clínica y Experimental, Antioquía, Colombia.

Background: Several reports show deficiencies in the knowledge of physicians about the diagnostic criteria and the treatment of anaphylaxis, a condition that can have fatal consequences.

Objective: To evaluate the knowledge of physicians in Colombia on the fundamental aspects of anaphylaxis in diagnosis and treatment.

Methods: Analytical cross-sectional study, carried out through a survey of 11 questions that evaluate clinical aspects of anaphylaxis, addressed to general practitioners and specialists in different health areas resident in Colombia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29262/ram.v66i1.524DOI Listing

[Allergy to food in adults with allergic respiratory diseases: prevalence and clinical manifestations].

Rev Alerg Mex 2019 Jan-Mar;66(1):1-8

Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Servicio de Alergia e Inmunología Clínica, Guadalajara, México.

Background: Food allergy is considered a typical problem in the pediatric population, however, cases occur in adults more frequently.

Objective: To determine the prevalence of food allergy in patients with allergic rhinitis and asthma; as well as the foods and symptoms most related to said problem.

Methods: Through a cross-sectional study, the information of 257 adults with asthma or allergic rhinitis was analyzed. Read More

View Article

Download full-text PDF

Source
http://revistaalergia.mx/ojs/index.php/ram/article/view/400
Publisher Site
http://dx.doi.org/10.29262/ram.v66i1.400DOI Listing
April 2019
3 Reads

Parent and child perception of quality of life in a randomized controlled peanut oral immunotherapy trial.

Pediatr Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Division of Pediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.

Background: Improved quality of life (QoL) after oral immunotherapy (OIT) in peanut allergic children is often reported by their parents, while the child's perspective is less clear.

Objective: We aimed to explore if two years of OIT improved QoL in children with peanut allergy and to identify factors influencing change in QoL.

Methods: In the open labelled TAKE-AWAY peanut OIT trial including children with anaphylaxis to peanuts, 57 were randomized to OIT and 20 to observation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pai.13066DOI Listing

Beneficial effect of nasal saline irrigation in children with allergic rhinitis and asthma: A randomized clinical trial.

Asian Pac J Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Asthma and allergic rhinitis (AR) are chronic inflammatory diseases of airway and affect the disease severity each other.

Objective: We performed this study to examine whether nasal saline irrigation (NSI) improves bronchial hyperresponsiveness and clinical parameters in children with asthma and allergic rhinitis (AR).

Methods: We enrolled 20 children with AR and asthma aged between 6-18 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12932/AP-070918-0403DOI Listing

Natural resolution of non-anaphylactic shrimp allergy in patients diagnosed 10 years earlier by oral food challenge.

Asian Pac J Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Division of Allergy and Clinical Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Shrimp allergy is considered a lifelong condition. The natural resolution of shrimp allergy is not well studied.

Objective: To investigate the natural resolution of shrimp allergy among a cohort of patients diagnosed with shrimp allergy 10 years earlier by oral shrimp challenge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12932/AP-080119-0470DOI Listing

Elevated levels of periostin and TGF-β1 in the bronchoalveolar lavage fluid of patients with idiopathic eosinophilic pneumonia.

Asian Pac J Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Department of Respiratory Medicine, Kawasaki Medical School, Okayama.

Background: Periostin is induced in bronchial epithelial cells and fibroblasts by various stimuli including interleukin (IL)13 and transforming growth factor (TGF)-β1, and is involved in allergic diseases such as asthma and atopic dermatitis, playing an important role in tissue remodeling and fibrosis. The role of periostin in the pathogenesis of eosinophilic lung diseases, however, is unclear.

Objective: To examine the contribution of periostin to eosinophilic inflammation of the lung in humans, we evaluated periostin, IL-13, and TGF-β1 levels in the bronchoalveolar lavage fluid (BALF) of patients with eosinophilic pneumonia (EP). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12932/AP-111018-0414DOI Listing

A study on the effect of nutrient intake on the body mass index of mothers of children with food allergies.

Asian Pac J Allergy Immunol 2019 Apr 23. Epub 2019 Apr 23.

Department of Pediatrics, Osaka Prefecture Medical Center for Respiratory and Allergic Diseases, 3-7-1, Habikino, Habikino, Osaka Prefecture, 583-8588, Japan.

Background: No previous studies have reported the effect of the presence of children with food allergies (FAs) on the diet and body mass index (BMI) of mothers. Therefore, we conducted a dietary survey and considered nutrients that influenced BMI of mothers.

Objective: Subjects included 554 mothers-305 mothers of children with FAs (FA mothers; aged 38. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12932/AP-260718-0377DOI Listing

Associations between breastfeeding rates and infant disease: A survey of 2338 Czech children.

Nutr Diet 2019 Apr 22. Epub 2019 Apr 22.

Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic.

Aim: Evidence has demonstrated that breastfeeding is the optimal nutrition for infants. The present study aims to report possible associations of the duration of full or partial breastfeeding with selected health outcomes during infancy.

Methods: Data from 2304 mothers were obtained by online mother-reported questionnaires at the age of 1 year of the child, providing information on full and partial breastfeeding durations, the frequency of infant upper respiratory tract infections and possible antibiotics use, and the occurrence of allergic diseases. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/1747-0080.12
Publisher Site
http://dx.doi.org/10.1111/1747-0080.12532DOI Listing
April 2019
1 Read

Linear Cutaneous Hypopigmentation and Atrophy Associated With Intralesional Steroid Injection: A Rarely Described Adverse reaction.

Dermatol Ther 2019 Apr 22:e12941. Epub 2019 Apr 22.

Dermatology Department, Sapienza University of Rome, Rome, Italy.

Intralesional steroid injection is a common and highly effective treatment procedure, which can be successfully used for several dermatologic, rheumatologic and orthopedic disorders. However, it may be associated with various local side effects, such as pain, granulomatous reaction, allergic reactions, hypo- or hyperpigmentation and, uncommonly, skin atrophy. A peculiar and rare side effect of steroid injection is linear hypopigmentation and atrophy, which is probably an expression of lymphatic spread of corticosteroid crystals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dth.12941DOI Listing

Patients with atopy exhibit reduced cortisol awakening response but not cortisol concentrations during the rest of the day.

Immunol Res 2019 Apr 22. Epub 2019 Apr 22.

Laboratory of Pharmacological Neuroendocrinology, Institute of Experimental Endocrinology, Biomedical Research Center of the Slovak Academy of Sciences, Bratislava, Slovakia.

It has been documented that cortisol release in response to acute stressors is reduced in patients with atopic dermatitis, allergic rhinitis, and other atopic diseases compared to that in healthy subjects. We aimed to test the hypothesis that atopic patients exert reduced salivary cortisol awakening response (CAR) in comparison with healthy subjects. The hypothesis was tested on a stressful and a relax day selected subjectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12026-019-09076-wDOI Listing

A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP.

J Immunol 2019 Apr 22. Epub 2019 Apr 22.

National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom;

To evade the immune system, the lethal human pathogen produces SpyCEP, an enzyme that cleaves the C-terminal α-helix of CXCL8, resulting in markedly impaired recruitment of neutrophils to sites of invasive infection. The basis for chemokine inactivation by SpyCEP is, however, poorly understood, as the core domain of CXCL8 known to interact with CXCL8 receptors is unaffected by enzymatic cleavage. We examined the in vitro migration of human neutrophils and observed that their ability to efficiently navigate a CXCL8 gradient was compromised following CXCL8 cleavage by SpyCEP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1801688DOI Listing

Clustering asthma symptoms and cleaning and disinfecting activities and evaluating their associations among healthcare workers.

Int J Hyg Environ Health 2019 Apr 19. Epub 2019 Apr 19.

Respiratory Health Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), Morgantown, WV, USA. Electronic address:

Asthma is a heterogeneous disease with varying severity and subtypes. Recent reviews of epidemiologic studies have identified cleaning and disinfecting activities (CDAs) as important risk factors for asthma-related outcomes among healthcare workers. However, the complexity of CDAs in healthcare settings has rarely been examined. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijheh.2019.04.001DOI Listing

SCIT Versus SLIT: Which One Do You Recommend, Doc?

Am J Med Sci 2019 May 10;357(5):442-447. Epub 2019 Feb 10.

Department of Otolaryngology, Emory University, Atlanta, Georgia.

Allergic rhinitis is a prevalent condition that has a significant impact on the quality of life of many patients. When initial therapy fails to control the symptoms, allergen immunotherapy (AIT) has been suggested as an option by the Joint Task Force on Practice Parameters. The 2 main forms of AIT are via subcutaneous and sublingual routes, called subcutaneous immunotherapy and sublingual immunotherapy, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjms.2019.02.004DOI Listing

Basophil involvement in lupus nephritis: a basis for innovation in daily care.

Nephrol Dial Transplant 2018 Jul 25. Epub 2018 Jul 25.

Centre de Recherche sur l'Inflammation, INSERM UMR1149, CNRS ERL8252, Université Paris Diderot, Sorbonne Paris Cité, Faculté de Médecine site Bichat, Laboratoire d'Excellence Inflamex, DHU FIRE, Paris, France.

Lupus nephritis (LN) affects a large proportion of patients with systemic lupus erythematosus (SLE). LN can lead to end-stage renal disease depending on when it is diagnosed and on the adequacy of the treatment administered to the patient based on the class of LN. Determination of the class and activity of LN is only possible by histological analysis of kidney biopsies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ndt/gfy245DOI Listing
July 2018
1 Read

Pharmaceutical and preclinical evaluation of Advax adjuvant as a dose-sparing strategy for ant venom immunotherapy.

J Pharm Biomed Anal 2019 Apr 9;172:1-8. Epub 2019 Apr 9.

Jack Jumper Allergy Program, Royal Hobart Hospital, GPO Box 1061L, Hobart, Tasmania, 7001, Australia; School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, South Australia, 5001, Australia.

A major challenge in broader clinical application of Jack Jumper ant venom immunotherapy (JJA VIT) is the scarcity of ant venom which needs to be manually harvested from wild ants. Adjuvants are commonly used for antigen sparing in other vaccines, and thereby could potentially have major benefits to extend JJA supplies if they were to similarly enhance JJA VIT immunogenicity. The purpose of this study was to evaluate the physicochemical and microbiological stability and murine immunogenicity of low-dose JJA VIT formulated with a novel polysaccharide adjuvant referred to as delta inulin or Advax™. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2019.04.017DOI Listing

Real-life safety of 5-grass pollen tablet in 5-to-9-year-old children with allergic rhinoconjunctivitis.

Ann Allergy Asthma Immunol 2019 Apr 19. Epub 2019 Apr 19.

Pediatric Pneumology and Allergology unit, Necker-Enfants Malades Hospital, Paris, France; Université Paris Descartes, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anai.2019.04.011DOI Listing

Report of a rare case of severe allergic reaction due to nasal myiasis and a brief review of the literature in Turkey.

SAGE Open Med Case Rep 2019 10;7:2050313X19843390. Epub 2019 Apr 10.

Department of Clinical Microbiology, School of Medicine, Hitit University, Çorum, Turkey.

Myiasis is defined as infestation of a mammal by fly larvae. It may occur on either living tissues (primary myiasis) or dead tissues (secondary myiasis). In this report, we present a patient with myiasis with an extremely rare clinical manifestation and severe allergic reaction, and we review the literature in order to reveal the current status. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/2050313X19843390
Publisher Site
http://dx.doi.org/10.1177/2050313X19843390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458663PMC
April 2019
1 Read

Skin microdialysis: methods, applications and future opportunities-an EAACI position paper.

Clin Transl Allergy 2019 10;9:24. Epub 2019 Apr 10.

3Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

Skin microdialysis (SMD) is a versatile sampling technique that can be used to recover soluble endogenous and exogenous molecules from the extracellular compartment of human skin. Due to its minimally invasive character, SMD can be applied in both clinical and preclinical settings. Despite being available since the 1990s, the technique has still not reached its full potential use as a tool to explore pathophysiological mechanisms of allergic and inflammatory reactions in the skin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13601-019-0262-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456961PMC

Leukotriene Receptor Antagonist Addition to H1-Antihistamine Is Effective for Treating Allergic Rhinitis: A Systematic Review and Meta-analysis.

Am J Rhinol Allergy 2019 Apr 22:1945892419844459. Epub 2019 Apr 22.

1 Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Histamine and leukotriene are released after being triggered by allergen exposure. The combination of leukotriene receptor antagonist (LTRA) and H1-antihistamine (AH) is utilized to control the allergic rhinitis (AR) symptoms after the failure of either AH or LTRA.

Objective: This study aimed to investigate the effects of the combination of H1-antihistamine and leukotriene receptor antagonist (AH-LTRA) in patients with AR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1945892419844459DOI Listing

Self-induced, noninflammatory alopecia associated with infestation with Lynxacarus radovskyi: a series of 11 cats.

Vet Dermatol 2019 Apr 21. Epub 2019 Apr 21.

The Cat Clinic, Block 109 Clementi Street 11, #01-33, Singapore City, 120109, Singapore.

Background: Infestation of Lynxacarus radovskyi (Lynxacarosis) on cats is usually asymptomatic - most cats are presented with a dull, dry, dishevelled coat, with easily epilated hairs. The physical presence of the mite gives the coat a "peppered" appearance, and previous reports have described some cats developing pruritus and alopecia.

Objectives: To describe the clinical signs of Lynxacarus radovskyi associated self-induced alopecia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/vde.12749DOI Listing

The preservative 2-(thiocyanomethylthio) benzothiazole: a potential allergen in leather products.

Contact Dermatitis 2019 Apr 21. Epub 2019 Apr 21.

Department of Dermatology, Cliniques universitaires Saint-Luc, Brussels, Belgium.

Background: Allergic contact dermatitis (ACD) from leather is common, and several responsible allergens, such as tanning agents, glues, mercaptobenzothiazole- derivatives, dyes, but also antimicrobials and antifungals are involved.

Material And Methods: Three female patients were referred to the Departments of Dermatology in a Belgian university hospital following skin reactions caused by leather products (shoes, belt, and car seats). They were patch tested with the European Baseline Series and samples of suspected leather products, and additionally with 2-(thiocyanomethylthio)benzothiazole (TCMTB), an antifungal agent previously reported as a contact allergen in footwear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13295DOI Listing

Evaluation of in vitro testing strategies for hazard assessment of the skin sensitization potential of "real-life" mixtures: the case of henna-based hair coloring products containing p-phenylenediamine.

Contact Dermatitis 2019 Apr 21. Epub 2019 Apr 21.

Laboratory of Education and Research in In Vitro Toxicology - Tox In, Faculty of Pharmacy, Federal University of Goiás, Goiânia, GO, Brazil.

Background: Allergic contact dermatitis reported to henna-based hair coloring products (HPs) has been associated with adulteration of henna with p-phenylenediamine (PPD).

Objectives: To develop a testing approach based on in vitro techniques that address key events within the skin sensitization adverse outcome pathway to evaluate allergenic potential of HPs.

Methods: The following in vitro assays were used to test the sensitizing capacity of hair dye ingredients: micro-direct peptide reactivity assay (mDPRA); HaCaT keratinocytes-associated IL-18 assay; U937 cell line activation test (USENS)/IL-8 levels; blood monocyte-derived dendritic cell test; genomic allergen rapid detection (GARD skin). Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13294
Publisher Site
http://dx.doi.org/10.1111/cod.13294DOI Listing
April 2019
4 Reads