Neurol Neuroimmunol Neuroinflamm 2022 05 21;9(3). Epub 2022 Mar 21.
From the Department of Neurology (L.A., J.M., K.S., D.H., A.-M.B., H.S., B.F., C.S., K.D.), University Hospital of Würzburg; Department of Neurology (I.A., K.P.), St. Josef Hospital Bochum, Ruhr University of Bochum, Germany; Department of Neurology (I.A.), I.M. Sechenov First Moscow State Medical University, Russia; Department of Neurology (F.B., C.D.), University Medical Center of the Johannes Gutenberg University, Mainz; Department of Neurology (J.D., S.M.), University Hospital Ulm; German Center for Neurodegenerative Diseases (DZNE) (J.D.), Ulm; Department of Neurologic Rehabilitation (F.D.), Asklepios Schloßberg-Klinik, Bad König; Department of Neurology (A.G.), Tübingen University Hospital; Hans Berger Department of Neurology (A.J.), Jena University Hospital; Neuroimmunology Section (F.L.), Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/Lübeck; Department of Neurology (F.L.), Kiel University; Department of Neurology (M.M.), Klinikum Würzburg Mitte gGmbH, Standort Juliusspital; Department of Neurology (P.M.), LVR-Klinik, Bonn; Department of Pathology (M.R.), Julius Maximilian University of Würzburg; Department of Neurology (A.-D.S.), Sächsisches Krankenhaus Altscherbitz, Schkeuditz; Department of Neurology (M.W.), Bundeswehrkrankenhaus Ulm; and Department of Neurology (G.S.W.), KRH Klinikum Nordstadt, Hannover, Germany.
Background And Objectives: Nodo-paranodopathies are peripheral neuropathies with dysfunction of the node of Ranvier. Affected patients who are seropositive for antibodies against adhesion molecules like contactin-1 and neurofascin show distinct clinical features and a disruption of the paranodal complex. An axoglial dysjunction is also a characteristic finding of diabetic neuropathy. Read More