Negative Affectivity, Depression, and Resting Heart Rate Variability (HRV) as Possible Moderators of Endogenous Pain Modulation in Functional Somatic Syndromes.
- Maaike Van Den Houte,
- Lukas Van Oudenhove,
- Ilse Van Diest,
- Katleen Bogaerts,
- Philippe Persoons,
- Jozef De Bie,
- Omer Van den Bergh
Front Psychol 2018 6;9:275. Epub 2018 Mar 6.
Health Psychology, Faculty of Psychology and Educational Sciences, University of Leuven, Leuven, Belgium.
Several studies have shown that patients with functional somatic syndromes (FSS) have, on average, deficient endogenous pain modulation (EPM), as well as elevated levels of negative affectivity (NA) and high comorbidity with depression and reduced resting heart rate variability (HRV) compared to healthy controls (HC). The goals of this study were (1) to replicate these findings and (2) to investigate the moderating role of NA, depression, and resting HRV in EPM efficiency within a patient group with fibromyalgia and/or chronic fatigue syndrome (CFS). Resting HRV was quantified as the root mean square of successive differences between inter-beat intervals (RMSSD) in rest, a vagally mediated time domain measure of HRV. Read More