1,855 results match your criteria Chorioretinopathy Central Serous


Mineralocorticoid Receptor Antagonists in Central Serous Chorioretinopathy: A Meta-Analysis of Randomized Controlled Trials.

Ophthalmol Retina 2019 Feb 15;3(2):154-160. Epub 2018 Sep 15.

Division of Ophthalmology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts. Electronic address:

Topic: A meta-analysis comparing mineralocorticoid receptor (MR) antagonists (eplerenone or spironolactone) versus observation or placebo in the treatment of central serous chorioretinopathy (CSCR) based on best-corrected visual acuity (BCVA) and subretinal fluid (SRF) level data from randomized controlled trials (RCTs).

Clinical Relevance: Central serous chorioretinopathy patients may demonstrate decreased visual acuity, reduced contrast sensitivity, scotomas, and metamorphopsia. Although multiple treatment options for CSCR have been proposed, compelling evidence for any particular method is still lacking. Read More

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http://dx.doi.org/10.1016/j.oret.2018.09.003DOI Listing
February 2019

Choroidal Neovascularisation Complicating Chronic Central Serous Chorioretinopathy: The Discovery Rate on Multimodal Imaging.

Klin Monbl Augenheilkd 2019 Apr 18;236(4):536-541. Epub 2019 Apr 18.

Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.

Purpose: To identify the image modality allowing identification of choroidal neovascularisation (CNV) complicating chronic central serous chorioretinopathy (CSCR), including fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography angiography (OCT-A).

Methods: Patients diagnosed with chronic CSCR and secondary CNV were included in the study. The image modalities FA, ICGA, and OCT-A were reviewed for specific CNV signs permitting diagnosis. Read More

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http://dx.doi.org/10.1055/a-0834-6118DOI Listing

Clinical Application of Fluorescein Angiography-Free Navigated Focal Laser Photocoagulation in Central Serous Chorioretinopathy.

Ophthalmic Surg Lasers Imaging Retina 2019 Apr;50(4):e118-e124

Background And Objective: To present clinical application of fluorescein angiography (FA)-free focal laser photocoagulation (FLP) of the leakage point in patients with central serous chorioretinopathy (CSC).

Patients And Methods: A prospective case series included 16 eyes of 16 patients with non-resolved CSC. The leakage point was identified with optical coherence tomography (OCT) as a small single pigment epithelium detachment (PED) localized in the upper half of the neurosensory detachment with an area of photoreceptor outer segments layer thinning above this PED. Read More

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http://dx.doi.org/10.3928/23258160-20190401-16DOI Listing

Optical Coherence Tomography Angiography Compared with Indocyanine Green Angiography in Central Serous Chorioretinopathy.

Sci Rep 2019 Apr 16;9(1):6149. Epub 2019 Apr 16.

Ophthalmology Optometry Centre, Peking University People's Hospital, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, 100044, China.

The purpose of this article is to compare optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC). OCTA, ICGA and fluorescein angiography (FA) images of all enrolled patients were collected and compared. Abnormal areas were annotated on en face choriocapillaris OCTA and ICGA images and compared with each other. Read More

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http://dx.doi.org/10.1038/s41598-019-42623-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467994PMC

Sensitivity and Specificity of Potential Diagnostic Features Detected Using Fundus Photography, Optical Coherence Tomography, and Fluorescein Angiography for Polypoidal Choroidal Vasculopathy.

JAMA Ophthalmol 2019 Apr 11. Epub 2019 Apr 11.

Wilmer Eye Institute, Retina Division, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Importance: The use of indocyanine green angiography (ICGA) is a criterion standard for diagnosing polypoidal choroidal vasculopathy (PCV), an endemic and common cause of vision loss in Asian and African individuals that also presents in white individuals. However, the use of ICGA is expensive, invasive, and not always available at clinical centers. Therefore, knowing the value of certain features detected using fundus photography (FP), optical coherence tomography (OCT), and fluorescein angiography (FA) to diagnose PCV without ICGA could assist ophthalmologists to identify PCV when ICGA is not readily available. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2019.0565DOI Listing

Test performance of optical coherence tomography angiography in detecting retinal diseases: a systematic review and meta-analysis.

Eye (Lond) 2019 Apr 10. Epub 2019 Apr 10.

Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland.

Objective: To investigate the diagnostic accuracy of optical coherence tomography angiography (OCTA) in detecting vascular characteristics of chorio-retinal disease.

Methods: Evidence acquisition: We searched Web of Science, Scopus, and Medline by the citation of references and complemented these electronic searches by checking the list of references of included and review articles. Screening, selection, assessment, and extraction was performed in parallel by two authors. Read More

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http://dx.doi.org/10.1038/s41433-019-0421-3DOI Listing

Anatomical and Functional Changes of the Retina and the Choroid after Resolved Chronic CSCR.

J Clin Med 2019 Apr 7;8(4). Epub 2019 Apr 7.

Eye Clinic, Polytechnic University of Marche, 60126 Ancona, Italy.

Background: To investigate anatomical/functional changes after oral eplerenone therapy for chronic central serous chorioretinopathy (CCSC) in successfully treated eyes and fellow eyes and assess timing of foveal subretinal fluid (SRF) resolution.

Methods: Twenty-one eyes of 21 patients suffering from CCSC with monolateral foveal SRF successfully treated with oral eplerenone were enrolled in this retrospective study (group 1). The fellow eyes (21 eyes; group 2), healthy or affected by CCSC, without foveal SRF were considered in the analysis. Read More

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https://www.mdpi.com/2077-0383/8/4/474
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http://dx.doi.org/10.3390/jcm8040474DOI Listing
April 2019
4 Reads

Focal and diffuse chronic central serous chorioretinopathy treated with half-dose photodynamic therapy or subthreshold micropulse laser.

Am J Ophthalmol 2019 Apr 2. Epub 2019 Apr 2.

Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; Amsterdam UMC, University of Amsterdam, Department of Ophthalmology, Meibergdreef 9, Amsterdam, Netherlands. Electronic address:

Purpose: To compare the outcome between high-density subthreshold micropulse laser (HSML) treatment and half-dose photodynamic therapy (PDT) in chronic central serous chorioretinopathy (cCSC) patients, subdivided based on either focal or diffuse leakage on fluorescein angiography (FA). Design; Retrospective analysis of multicenter randomized controlled trial data METHODS: Patients were treated with either half-dose PDT or HSML (both ICGA-guided) and categorized in 2 groups, based on focal or diffuse leakage on FA. Clinical outcomes were evaluated at baseline and during follow-up. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.03.025DOI Listing
April 2019
1 Read

The relationship between foveal outer nuclear layer thickness in the active and resolved phases of central serous chorioretinopathy treated with half-dose photodynamic therapy.

BMC Ophthalmol 2019 Mar 29;19(1):84. Epub 2019 Mar 29.

Department of Ophthalmology, Eye & Ear Nose Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.

Background: To investigate the relationship between the foveal outer nuclear layer (ONL) thickness in the active and resolved phases of central serous chorioretinopathy (CSC), and its possible association with optical coherence tomography (OCT) parameters.

Methods: The medical records of CSC patients treated with half-dose photodynamic therapy (PDT) between August 2011 and October 2017 were reviewed. The difference between the foveal ONL thickness at 12 m after half-dose PDT and that before half-dose PDT was analyzed, and its association with OCT parameters was assessed using generalized linear models. Read More

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http://dx.doi.org/10.1186/s12886-019-1089-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440016PMC
March 2019
2 Reads
1.075 Impact Factor

A Backward Glance at Chronic Central Serous Chorioretinopathy.

Ophthalmology 2019 Apr;126(4):589-590

Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2018.11.012DOI Listing

COMPARISON OF VISUAL/ANATOMICAL OUTCOMES AND RECURRENCE RATE BETWEEN ORAL SPIRONOLACTONE AND PHOTODYNAMIC THERAPY FOR NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY.

Retina 2019 Mar 11. Epub 2019 Mar 11.

Department of Ophthalmology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.

Purpose: To compare long-term visual/anatomical outcomes and recurrence rate between oral spironolactone (SPRL) treatment and half-dose photodynamic therapy for nonresolving central serous chorioretinopathy.

Methods: This retrospective, interventional, comparative study included 50 nonresolving central serous chorioretinopathy patients who had exhibited subretinal fluid (SRF) accumulation for >3 months. Of the 50 patients, 26 (26 eyes) received oral SPRL treatment and 24 (24 eyes) received half-dose photodynamic therapy. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002507DOI Listing
March 2019
2 Reads

Pachychoroid Pigment Epitheliopathy and Choroidal Thickness Changes in Coeliac Disease.

J Ophthalmol 2019 13;2019:6924191. Epub 2019 Feb 13.

University of Health Sciences, Okmeydani Training and Research Hospital, Department of Gastroenterology, Istanbul, Turkey.

Purpose: To evaluate choroidal thickness in patients with coeliac disease (CD) using spectral domain optical coherence tomography (SD-OCT) and to compare the results to normal eyes.

Methods: Seventy patients with CD and 70 healthy controls were included in this prospective, comparative study. All participants underwent a complete ophthalmologic evaluation and SD-OCT. Read More

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http://dx.doi.org/10.1155/2019/6924191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394117PMC
February 2019

Increased risk of central serous chorioretinopathy following end-stage renal disease: A nationwide population-based study.

Medicine (Baltimore) 2019 Mar;98(11):e14859

Graduate Institute of Medical Science, College of Health Science, Chang Jung Christian University, Tainan.

This retrospective, nationwide, matched cohort study investigated the risk of central serous chorioretinopathy (CSCR) following end-stage renal disease (ESRD). The study cohort included 84722 ESRD patients who were registered between January 2000 and December 2009 at the Taiwan National Health Insurance Research Database. An age- and sex-matched control group comprised 84722 patients selected from the Taiwan Longitudinal Health Insurance Database 2000. Read More

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http://dx.doi.org/10.1097/MD.0000000000014859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426587PMC
March 2019
7 Reads

Clinical characteristics of pachydrusen in central serous chorioretinopathy.

Graefes Arch Clin Exp Ophthalmol 2019 Mar 9. Epub 2019 Mar 9.

Department of Ophthalmology, Gunma University, School of Medicine, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan.

Purpose: To evaluate the clinical characteristics of pachydrusen in central serous chorioretinopathy (CSC) and investigate the relationship between choroidal circulation and pachydrusen.

Methods: In a retrospective case series of 302 eyes of 151 patients with treatment-naïve CSC, we assessed the incidence of pachydrusen and their features on indocyanine green angiography (ICGA) and optical coherence tomography (OCT).

Results: Pachydrusen were observed in 82 of the 302 eyes (27. Read More

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http://dx.doi.org/10.1007/s00417-019-04284-4DOI Listing

Risk Factors and Outcomes of Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy.

Sci Rep 2019 Mar 8;9(1):3927. Epub 2019 Mar 8.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

We identified clinical characteristics and risk factors of choroidal neovascularization (CNV) in eyes with prior episode of central serous chorioretinopathy (CSC). This retrospective case-control study included those initially diagnosed with CSC and developed CNV secondarily (Group 1, n = 16), those diagnosed with CNV in eyes of previous putative CSC (Group 2, n = 14), and those initially diagnosed with CSC, and did not develop CNV secondarily, as a control group for Group 1 (Group 3, n = 250). Clinical characteristics including treatment outcomes were assessed. Read More

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http://dx.doi.org/10.1038/s41598-019-40406-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408555PMC
March 2019
2 Reads

Choroidal neovascularization emerged right from the focal choroidal excavation in eyes with central serous chorioretinopathy post half-dose photodynamic therapy: a case report.

BMC Ophthalmol 2019 Mar 8;19(1):68. Epub 2019 Mar 8.

Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, 200032, China.

Background: Focal choroidal excavation (FCE) is a common concurrent disease with central serous chorioretinopathy (CSC) and choroidal neovascularization (CNV). Photodynamic therapy (PDT) was able to cease the course of CSC with efficacy and safety. To retrospectively observed and followed up a special course in eyes with CSC and concurrent FCE treated by a half-dose of PDT. Read More

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http://dx.doi.org/10.1186/s12886-019-1081-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408815PMC
March 2019
1 Read
1.075 Impact Factor

Central Serous Chorioretinopathy: A Complication Associated with Behçet’s Disease Treatment

Turk J Ophthalmol 2019 Feb;49(1):40-43

Dokuz Eylül University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey

Central serous chorioretinopathy (CSCR) is characterized by a well-defined serous choroidal detachment of the retinal pigment epithelium with one or more focal lesions of the neurosensory retina. Risk factors for CSCR are psychosocial stress, increased endogenous catecholamine, and increased endogenous cortisol. Systemic steroids can cause ocular side effects such as cataract development, increased intraocular pressure, and less frequently the development of CSCR, which can resolve spontaneously with close follow-up and simple treatment modification. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2018.83479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416479PMC
February 2019
1 Read

Current Therapeutic Approaches to Chronic Central Serous Chorioretinopathy

Turk J Ophthalmol 2019 Feb;49(1):30-39

Marmara University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey

Central serous chorioretinopathy (CSCR) is the second most common maculopathy after diabetic maculopathy between the third and fifth decades of life. CSCR is characterized by serous neurosensory retinal detachment occasionally coexisting with retinal pigment epithelium (RPE) detachment. CSCR usually has good clinical prognosis, often resolving spontaneously within the first three months. Read More

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http://dx.doi.org/10.4274/tjo.galenos.2018.49035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416476PMC
February 2019
1 Read

Non-resolving, recurrent and chronic central serous chorioretinopathy: available treatment options.

Eye (Lond) 2019 Mar 1. Epub 2019 Mar 1.

Ophthalmology, Department of Surgery, Medicine, Molecular and Emergency, University of Pisa, Pisa, Italy.

Central serous chorioretinopathy is one of the most frequent causes of vision reduction among middle-aged men. This disease usually has a self-limiting course, but sometimes it lasts more than 4-6 months or a second episode follows a complete resolution of the first one. Nevertheless, to date no consensus exists about the duration threshold and therapy protocols for these non-resolving central serous chorioretinopathy. Read More

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http://dx.doi.org/10.1038/s41433-019-0381-7DOI Listing
March 2019
1.897 Impact Factor

Central serous chorioretinopathy with and without steroids: A multicenter survey.

PLoS One 2019 28;14(2):e0213110. Epub 2019 Feb 28.

Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan.

We investigated the rates of the use of steroids in Japanese central serous chorioretinopathy (CSC) cases and differences in the characteristics of CSC with and without steroids. A total of 538 eyes of 477 patients diagnosed with CSC, with 3 months or more of follow-up between April 2013 and June 2017 at 8 institutions. Patients with CSC with more than 3 months of follow-up were identified by OCT and fluorescein angiography at 8 institutions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213110PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394983PMC
February 2019
3 Reads

Optical coherence tomography angiography findings in fellow eyes of choroidal neovascularisation associated with central serous chorioretinopathy.

Br J Ophthalmol 2019 Feb 23. Epub 2019 Feb 23.

Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, L V Prasad Eye Institute, Hyderabad, Telangana, India

Aim: To evaluate the optical coherence tomography angiography (OCTA) features of fellow eyes of patients with unilateral choroidal neovascularisation (CNV) associated with chronic central serous chorioretinopathy (CSCR).

Methods: Medical records of patients with chronic CSCR who had undergone OCT angiography of both the eyes were reviewed. Patients with evidence of unilateral CNV detected by conventional imaging (OCT, fluorescein angiography and/or indocyanine green angiography) were included in the study. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3135
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http://dx.doi.org/10.1136/bjophthalmol-2018-313576DOI Listing
February 2019
2 Reads

Micropulse Laser Treatment of Retinal Diseases.

Authors:
Maciej Gawęcki

J Clin Med 2019 Feb 13;8(2). Epub 2019 Feb 13.

Dobry Wzrok Ophthalmological Clinic, Kliniczna 1B/2, 80-402 Gdansk, Poland.

Subthreshold micropulse laser treatment has been intensively used for selected retinal diseases in the last decade; however, the exact mechanism of the action of lasers in the subthreshold micropulse mode is not yet fully understood. This kind of treatment is safe and cheap, and contrary to classic laser photocoagulation, it leaves the retinal cells intact. A modern theory of micropulse laser interaction with retinal tissue and a possible explanation of this mechanism are presented in this review. Read More

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http://dx.doi.org/10.3390/jcm8020242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406510PMC
February 2019

Treatment of large avascular retinal pigment epithelium detachments in age-related macular degeneration with aflibercept, photodynamic therapy, and triamcinolone acetonide.

Clin Ophthalmol 2019 1;13:233-241. Epub 2019 Feb 1.

Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU, Norwegian University of Science and Technology, 7491 Trondheim, Norway,

Purpose: To evaluate the use of aflibercept, triamcinolone acetonide, and photodynamic therapy (PDT) in the treatment of avascular pigment epithelium detachments (aPEDs).

Patients And Methods: Patients with treatment-naïve aPEDs ≥1,500 µm in diameter were randomized to treatment or observation. Treatment consisted of 6 monthly intravitreal injections of aflibercept. Read More

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http://dx.doi.org/10.2147/OPTH.S188315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362940PMC
February 2019
3 Reads

Effect of Serous Retinal Detachment on the Measurement of Axial Length in Central Serous Chorioretinopathy.

Korean J Ophthalmol 2019 Feb;33(1):63-69

Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Korea.

Purpose: To evaluate the changes of axial length (AXL) in eyes with unilateral idiopathic central serous chorioretinopathy (CSC) after resolution of serous retinal detachment.

Methods: A total of 31 patients diagnosed with idiopathic unilateral CSC were included in this study. The changes of AXL according to serous retinal detachment were examined. Read More

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http://dx.doi.org/10.3341/kjo.2018.0032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372381PMC
February 2019

Serous Retinal Detachment Causes a Transient Reduction on Spectral Domain OCT Estimates of Ganglion Cell Layer Thickness.

Optom Vis Sci 2019 Mar;96(3):156-163

Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.

Significance: During the acute stage of central serous chorioretinopathy (CSC) with retinal elevation, the spectral domain optical coherence tomography (SD-OCT) estimate of ganglion cell layer complex thickness is reduced. Thickness returns to normal after resolution of the event. Measurement error is at least partially responsible for this effect. Read More

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http://dx.doi.org/10.1097/OPX.0000000000001347DOI Listing

Pharmacotherapy for Choroidal Neovascularization Due to Uncommon Causes.

Curr Pharm Des 2018 ;24(41):4882-4895

Hong Kong Eye Hospital, Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong.

Background: Choroidal neovascularization (CNV) in adults is most commonly associated with neovascular age-related macular degeneration (AMD) and pathologic myopia. Though less common, CNV can also develop from other conditions such as uveitis, central serous chorioretinopathy, angioid streaks, intraocular tumors, hereditary chorioretinal dystrophies, or can be idiopathic in origin. If left untreated, CNV may cause visual loss because of exudation of intraretinal or subretinal fluid, retinal or subretinal hemorrhage, or fibrosis involving the macula. Read More

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http://dx.doi.org/10.2174/1381612825666190206105943DOI Listing
January 2018
3 Reads

Exome sequencing in families with chronic central serous chorioretinopathy.

Mol Genet Genomic Med 2019 04 6;7(4):e00576. Epub 2019 Feb 6.

Department of Ophthalmology, Donders Institute of Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Central serous chorioretinopathy (CSC) is a chorioretinal disease characterized by fluid accumulation between the neuroretina and retinal pigment epithelium with unknown etiology. Family studies have suggested a heritable component for CSC with an autosomal dominant inheritance pattern. Therefore, exome sequencing was performed on familial cCSC to indentify the genetic components contributing to familial cCSC. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mgg3.576
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http://dx.doi.org/10.1002/mgg3.576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465660PMC
April 2019
9 Reads

[Optical coherence tomography in diagnostics and treatment of central serous chorioretinopathy].

Vestn Oftalmol 2018;134(6):15-24

S.M. Kirov Military Medical Academy, Chair of Ophthalmology, 5 Klinicheskaya St., Saint Petersburg, Russian Federation, 194044.

Purpose: To identify the signs of leakage points in central serous chorioretinopathy (CSC) patients using optical coherence tomography (OCT) allowing focal laser photocoagulation (FLP) to be performed without the need for fluorescein angiography (FA) in their treatment; to evaluate the effectiveness and safety of the approach.

Material And Methods: The retrospective part of the study included 54 patients (54 eyes) with distinctive signs of CSC further confirmed by the presence of a leakage point as could be seen with FA. The number of pigment epithelial detachments (PED), the thickness of the photoreceptor outer segments (PROS) layer, maximum horizontal length of the photoreceptor thinning area, and morphological changes in the outer retinal layers were evaluated with OCT. Read More

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http://dx.doi.org/10.17116/oftalma201813406115DOI Listing
January 2018
2 Reads

A pilot prospective study of 577-nm yellow subthreshold micropulse laser treatment with two different power settings for acute central serous chorioretinopathy.

Lasers Med Sci 2019 Feb 2. Epub 2019 Feb 2.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou City, China.

To compare the efficacy of 50% threshold power with 25% threshold power of 577-nm subthreshold micropulse laser (SMPL) for acute central serous chorioretinopathy (CSC). Prospective, interventional, non-randomized, comparative case series. A total of 54 patients (54 eyes) with acute CSC were enrolled. Read More

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http://dx.doi.org/10.1007/s10103-019-02721-8DOI Listing
February 2019
4 Reads

Pharmacotherapy of Central Serous Chorioretinopathy: A Review of the Current Treatments.

Curr Pharm Des 2018 ;24(41):4864-4873

IRCCS Fondazione Bietti, Rome, Italy.

Background: Central serous chorioretinopathy (CSC) is the fourth most frequent retinal disorder in terms of prevalence. It typically occurs in young subjects and affects men more often than women. CSC is characterized by serous retinal detachment (SRD) involving mainly the macular area. Read More

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http://www.eurekaselect.com/169299/article
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http://dx.doi.org/10.2174/1381612825666190123165914DOI Listing
January 2018
5 Reads

Quetiapine associated Central Serous Chorioretinopathy: Implicit role of serotonin and dopamine pathways.

Authors:
Manish Jain

Indian J Ophthalmol 2019 Feb;67(2):292-294

Department of Ophthalmology, NMC Specialty Hospital, Al Ain, Abu Dhabi, UAE.

A 30-year-old insomniac, an off-label user of quetiapine, presented with blurring of central vision, eventually diagnosed as central serous chorioretinopathy. A potential association was suspected based on the drug's actions on the autonomic nervous system. He showed improvement on drug withdrawal; then he unwittingly resumed quetiapine and had a recurrence. Read More

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http://dx.doi.org/10.4103/ijo.IJO_929_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376803PMC
February 2019

Clinical profile of uveitis patients developing central serous chorioretinopathy: An experience at a tertiary eye care center in India.

Indian J Ophthalmol 2019 Feb;67(2):247-251

Department of Uvea and Ocular Pathology, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Purpose: To evaluate clinical profile of patients with uveitis who developed central serous chorioretinopathy (CSC).

Methods: Retrospective case series of consecutive patients of uveitis with CSC managed at a tertiary eye care center in India between 1994 and 2014. The data about clinical features, investigations, treatment, and outcomes were obtained from their medical records. Read More

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http://www.ijo.in/text.asp?2019/67/2/247/250684
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http://dx.doi.org/10.4103/ijo.IJO_831_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376845PMC
February 2019
8 Reads

Long-term Visual Outcomes and Causes of Vision Loss in Chronic Central Serous Chorioretinopathy.

Ophthalmology 2019 Apr 17;126(4):576-588. Epub 2019 Jan 17.

Vitreous, Retina, Macula Consultants of New York, New York; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York; Department of Ophthalmology, New York University School of Medicine, New York, New York.

Purpose: To evaluate the long-term visual outcomes and causes of vision loss in chronic central serous chorioretinopathy (CSC).

Design: Retrospective, longitudinal study.

Participants: A total of 133 participants (217 eyes) with chronic CSC. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01616420173206
Publisher Site
http://dx.doi.org/10.1016/j.ophtha.2018.12.048DOI Listing
April 2019
14 Reads

Optical Coherence Tomography Angiography Findings in Chronic Central Serous Chorioretinopathy After Photodynamic Therapy.

Ophthalmic Surg Lasers Imaging Retina 2019 01;50(1):25-32

Background And Objectives: To report the acute and long-term choroidal findings in patients with chronic central serous chorioretinopathy (CCSC) undergoing half-fluence photodynamic therapy (PDT).

Patients And Methods: This is a prospective, consecutive, interventional, noncomparative case series at a tertiary referral vitreoretinal practice. Twenty-one eyes from 21 patients are included. Read More

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http://dx.doi.org/10.3928/23258160-20181212-04DOI Listing
January 2019
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ELONGATED PHOTORECEPTOR OUTER SEGMENT LENGTH AND PROGNOSIS OF CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

Retina 2019 Jan 10. Epub 2019 Jan 10.

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Purpose: To evaluate the effect of elongated photoreceptor outer segment length on the visual prognosis of patients with chronic central serous chorioretinopathy after treatment using half-dose and half-fluence photodynamic therapy (reduced PDT).

Methods: The study included 36 eyes of 36 patients with chronic central serous chorioretinopathy who underwent reduced PDT and were followed up for at least 1 year. Spectral domain optical coherence tomography measurement was conducted at baseline and 12 months after reduced PDT. Read More

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http://Insights.ovid.com/crossref?an=00006982-900000000-9625
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http://dx.doi.org/10.1097/IAE.0000000000002445DOI Listing
January 2019
10 Reads

[Bilateral multifocal pigment epithelial detachments associated with inhaled corticosteroids].

Ophthalmologe 2019 Jan 9. Epub 2019 Jan 9.

Universitäts-Augenklinik Bonn, Ernst-Abbe-Str. 2, 53127, Bonn, Deutschland.

A 37-year-old male patient presented with metamorphopsia and unilateral visual impairment with the presence of hundreds of bilateral avascular retinal pigment epithelial detachments (PEDs). The patient suffered from allergic bronchial asthma which was treated with inhaled corticosteroids. Cessation of corticosteroid treatment resulted in flattening of larger PEDs and subsequent transition to atrophic areas over time while smaller PEDs persisted and spread peripherally over an observation period of 14½ years. Read More

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http://dx.doi.org/10.1007/s00347-018-0848-0DOI Listing
January 2019
3 Reads

Investigating the Hypothesis of Stress System Dysregulation as a Risk Factor for Central Serous Chorioretinopathy: A Literature Mini-Review.

Curr Eye Res 2019 Jan 9:1-7. Epub 2019 Jan 9.

a IRCCS -Fondazione Bietti , Rome , Italy.

Background: This mini-review addressed the question "what do we know about the association between the dysregulation of stress systems (HPA axis and SAM) and the onset and prognosis of CSC in adult populations?"

Methods: The literature mini-review was conducted through electronic searches using the PubMed, Web of Science, and Scopus databases. All published human and animal studies with both observational and experimental designs from 1966 to October 2018 were included.

Results: Our search identified 229 reports, of which 32 articles were ultimately identified to be reviewed in this paper. Read More

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http://dx.doi.org/10.1080/02713683.2019.1565891DOI Listing
January 2019
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OCT Angiography of the Choriocapillaris in Central Serous Chorioretinopathy: A Quantitative Subgroup Analysis.

Ophthalmol Ther 2019 Mar 7;8(1):75-86. Epub 2019 Jan 7.

Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Introduction: To quantify optical coherence tomography angiography (OCTA) signal changes at the level of the choriocapillaris (CC) in patients with different stages of central serous chorioretinopathy (CSC) and to explore any correlation between subretinal fluid (SRF) and retinal pigment epithelium (RPE) alterations and the OCTA CC signal.

Methods: One hundred one CSC eyes and 42 healthy control eyes were included in this retrospective study. CSC patients were allocated into four groups: acute, non-resolving, chronic atrophic and inactive CSC. Read More

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http://link.springer.com/10.1007/s40123-018-0159-1
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http://dx.doi.org/10.1007/s40123-018-0159-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393260PMC
March 2019
5 Reads

Vascular and structural alterations of the choroid evaluated by optical coherence tomography angiography and optical coherence tomography after half-fluence photodynamic therapy in chronic central serous chorioretinopathy.

Graefes Arch Clin Exp Ophthalmol 2019 May 7;257(5):905-912. Epub 2019 Jan 7.

Department of Ophthalmology, Ankara University Faculty of Medicine Ankara, Mamak Street, Dikimevi, Ankara, Turkey.

Purpose: To concurrently evaluate the effect of half-fluence photodynamic therapy (hf PDT) on choriocapillaris (CC) perfusion and choroidal structure in chronic central serous chorioretinopathy (CSC).

Methods: This prospective study included 48 eyes of 41 patients with chronic CSC. Enhanced depth imaging optical coherence tomography and optical coherence tomography angiography (OCTA) images were analyzed. Read More

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http://link.springer.com/10.1007/s00417-018-04226-6
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http://dx.doi.org/10.1007/s00417-018-04226-6DOI Listing
May 2019
2 Reads

Short-duration multiple-session subthreshold micropulse yellow laser (577 nm) for chronic central serous chorioretinopathy: results at 3 years.

Eye (Lond) 2019 Jan 4. Epub 2019 Jan 4.

Retina Center, Nune Eye Hospital, Daegu, Republic of Korea.

Objectives: To review the 3-year follow-up results of subthreshold micropulse yellow laser (SMYL) delivered by a short-duration multiple-session method for treatment of chronic central serous chorioretinopathy (CSC).

Methods: A total of 27 eyes from 27 patients with chronic CSC available for 3 years of follow-up were enrolled in this retrospective and interventional study. Patients were treated with 577-nm SMYL photocoagulation at a 15% duty cycle over multiple sessions, with low power ranging from 200 to 400 mW that was increased in 100 mW increments according to resolution of subretinal fluid at monthly follow-up. Read More

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http://dx.doi.org/10.1038/s41433-018-0309-7DOI Listing
January 2019
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CLINICAL APPLICATION OF MULTICOLOR IMAGING IN CENTRAL SEROUS CHORIORETINOPATHY.

Retina 2018 Dec 31. Epub 2018 Dec 31.

Eye Center, Renmin Hospital of Wuhan University, Wuhan, China.

Purpose: To characterize features of central serous chorioretinopathy (CSC) using multicolor (MC) imaging and to compare the efficacy of using MC imaging and traditional color fundus photography (CFP) for detecting features of CSC.

Methods: A retrospective review of 75 eyes of 69 participants with CSC from the Eye Center of the Renmin Hospital of Wuhan University. The patients underwent same-day CFP, fundus fluorescein angiography (FFA), spectral domain optical coherence tomography (SD-OCT), and MC imaging (including infrared reflectance (IR), green reflectance (GR), blue reflectance (BR), combined standard MC image, and green-blue-enhanced image). Read More

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http://Insights.ovid.com/crossref?an=00006982-900000000-9625
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http://dx.doi.org/10.1097/IAE.0000000000002441DOI Listing
December 2018
3 Reads

Optical coherence tomography angiography findings in cystoid macular degeneration associated with central serous chorioretinopathy.

Br J Ophthalmol 2019 Jan 2. Epub 2019 Jan 2.

Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, L V Prasad Eye Institute, Hyderabad, India

Aim: To describe the optical coherence tomography (OCT) characteristics and to identify and analyse the incidence of choroidal neovascular (CNV) network seen on optical coherence tomography angiography (OCTA) in eyes with cystoid macular degeneration (CMD) associated with central serous chorioretinopathy (CSCR).

Methods: This was a retrospective, observational study of 29 eyes of 25 patients who were previously diagnosed as CSCR with CMD. Baseline patient characteristics, best-corrected visual acuity (BCVA), evidence of CNV network and its pattern on OCTA, distribution of CMD changes and OCT parameters, such as height of the neurosensory retinal detachment (NSD), presence of double layer sign, central macular thickness, were analysed. Read More

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2018-3130
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http://dx.doi.org/10.1136/bjophthalmol-2018-313048DOI Listing
January 2019
12 Reads

[Does the micropulse laser have an effect on chronic CSC?]

Ophthalmologe 2018 Dec 21. Epub 2018 Dec 21.

Klinik für Augenheilkunde, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Introduction: Central serous chorioretinopathy (CSC) is the fourth most common cause of vision loss without an evidence-based treatment recommendation. A positive effect of micropulse laser (MPL) treatment has been described in the literature in recent years. This study aimed to reappraise these results in a patient population with chronic CSC. Read More

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http://dx.doi.org/10.1007/s00347-018-0839-1DOI Listing
December 2018
3 Reads

Peripheral retinal findings in populations with macular disease are similar to healthy eyes.

Ophthalmic Physiol Opt 2018 11;38(6):584-595

Centre for Eye Health, University of New South Wales, Sydney, Australia.

Purpose: Recent evidence suggests several macular diseases are associated with peripheral retinal changes. This study investigated the number, type and management consequences of peripheral retinal findings detected in patients attending a referral only, eye-care clinic, the Centre for Eye Health(CFEH) with macular disease.

Methods: Records of 537 patients attending CFEH for a macular assessment were included in the study. Read More

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http://doi.wiley.com/10.1111/opo.12589
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http://dx.doi.org/10.1111/opo.12589DOI Listing
November 2018
14 Reads

An unusual case of multifocal central serous chorioretinopathy with low serum cortisol managed using eplerenone.

Indian J Ophthalmol 2019 Jan;67(1):167-170

Advanced Eye Center, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.

In this report, we describe a rare case of a 44-year-old Asian male with acute central serous chorioretinopathy (CSC) with bullous exudative retinal detachment. Endocrinology evaluation revealed hypothalamic-pituitary-adrenal axis suppression with low serum cortisol. Furthermore, neuroimaging revealed the presence of a pituitary microadenoma. Read More

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http://dx.doi.org/10.4103/ijo.IJO_651_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324152PMC
January 2019
3 Reads